Mus musculus

206 known processes

Irf4

interferon regulatory factor 4

(Aliases: LSIRF,AI385587,Spip,IRF-4)

Irf4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cytokine biosynthetic processGO:0042035590.914
Human Mouse
lymphocyte differentiationGO:00300982420.913
adaptive immune responseGO:00022501550.909
leukocyte proliferationGO:00706611720.878
Mouse
cytokine biosynthetic processGO:0042089680.860
Human Mouse
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.858
regulation of alpha beta t cell activationGO:0046634530.809
Mouse
myeloid dendritic cell differentiationGO:0043011160.804
t cell activationGO:00421102890.780
regulation of lymphocyte proliferationGO:00506701170.762
Mouse
positive regulation of leukocyte proliferationGO:0070665730.735
t cell differentiationGO:00302171740.712
leukocyte differentiationGO:00025213420.693
alpha beta t cell activationGO:0046631910.691
dendritic cell differentiationGO:0097028260.658
cd4 positive alpha beta t cell differentiationGO:0043367410.655
cellular response to biotic stimulusGO:0071216920.639
Mouse
lymphocyte proliferationGO:00466511640.629
Mouse
positive regulation of interleukin 12 productionGO:0032735210.621
Mouse
positive regulation of cytokine biosynthetic processGO:0042108400.618
Human Mouse
interleukin 12 productionGO:0032615320.603
Mouse
t helper 17 cell lineage commitmentGO:007254040.586
cytokine metabolic processGO:0042107710.573
Human Mouse
myeloid leukocyte differentiationGO:00025731190.571
positive regulation of cytokine productionGO:00018191740.566
Human Mouse
immune effector processGO:00022523210.561
regulation of cell activationGO:00508652890.561
Mouse
lymphocyte activation involved in immune responseGO:0002285930.558
t cell differentiation involved in immune responseGO:0002292300.533
response to lipopolysaccharideGO:00324961280.528
Mouse
negative regulation of cell activationGO:00508661110.512
Mouse
inflammatory responseGO:00069542440.492
myeloid dendritic cell activationGO:0001773250.478
defense response to protozoanGO:0042832250.467
positive regulation of defense responseGO:00313491240.465
positive regulation of t cell activationGO:00508701010.462
immunoglobulin mediated immune responseGO:0016064690.459
Mouse
cell activation involved in immune responseGO:00022631260.452
b cell activation involved in immune responseGO:0002312500.448
regulation of interleukin 12 productionGO:0032655300.443
Mouse
regulation of alpha beta t cell proliferationGO:0046640180.439
Mouse
t cell activation involved in immune responseGO:0002286430.437
regulation of cellular amine metabolic processGO:0033238200.434
b cell activationGO:00421131610.428
regulation of lymphocyte activationGO:00512492400.410
Mouse
t cell selectionGO:0045058340.380
alpha beta t cell differentiationGO:0046632690.364
leukocyte activation involved in immune responseGO:00023661260.355
cellular amino acid metabolic processGO:00065201030.354
negative regulation of protein metabolic processGO:00512482820.353
Mouse
regulation of cellular ketone metabolic processGO:0010565660.349
regulation of b cell proliferationGO:0030888390.348
defense response to other organismGO:00985421970.344
leukocyte mediated immunityGO:00024431740.340
Mouse
t helper cell differentiationGO:0042093280.330
negative regulation of t cell activationGO:0050868650.330
Mouse
cd4 positive alpha beta t cell activationGO:0035710450.328
positive regulation of interferon alpha productionGO:003272740.326
Mouse
extrinsic apoptotic signaling pathwayGO:00971911260.320
interleukin 10 secretionGO:007260840.317
dna metabolic processGO:00062593030.315
negative regulation of regulatory t cell differentiationGO:004559020.311
Mouse
regulation of interferon gamma productionGO:0032649570.310
Mouse
cellular response to lipopolysaccharideGO:0071222770.294
Mouse
positive regulation of lymphocyte activationGO:00512511400.292
peptidyl amino acid modificationGO:00181933360.279
t helper 17 cell differentiationGO:007253970.277
alpha beta t cell activation involved in immune responseGO:0002287310.276
t cell receptor signaling pathwayGO:0050852460.272
regulation of b cell activationGO:0050864810.269
apoptotic signaling pathwayGO:00971903060.268
lymphocyte mediated immunityGO:00024491390.266
Mouse
regulation of leukocyte differentiationGO:19021051590.264
Mouse
cellular ketone metabolic processGO:0042180840.263
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.260
regulation of leukocyte proliferationGO:00706631210.260
Mouse
t cell proliferationGO:00420981200.258
Mouse
negative regulation of immune system processGO:00026832090.256
dna recombinationGO:0006310920.256
alpha beta t cell differentiation involved in immune responseGO:0002293300.255
production of molecular mediator of immune responseGO:00024401030.254
regulation of establishment of protein localizationGO:00702011810.250
cellular response to molecule of bacterial originGO:0071219830.249
Mouse
myeloid cell differentiationGO:00300992330.249
cytokine secretionGO:0050663720.247
immune response activating cell surface receptor signaling pathwayGO:0002429720.237
metal ion homeostasisGO:00550651890.237
positive regulation of cellular amino acid metabolic processGO:004576430.233
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.229
amine metabolic processGO:0009308450.227
cytokine productionGO:00018163190.225
Human Mouse
immune response activating signal transductionGO:00027571160.222
cellular metal ion homeostasisGO:00068751510.217
cellular response to cytokine stimulusGO:00713451890.214
Mouse
regulation of innate immune responseGO:0045088910.212
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.209
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.208
skin developmentGO:00435882200.207
Mouse
positive regulation of cell activationGO:00508671580.206
humoral immune responseGO:0006959570.203
positive regulation of cell deathGO:00109422240.201
regulation of membrane potentialGO:00423911920.200
somatic diversification of immunoglobulinsGO:0016445430.197
b cell mediated immunityGO:0019724710.191
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.191
cellular response to lipidGO:00713961450.187
Mouse
homeostasis of number of cellsGO:00488722100.187
positive t cell selectionGO:0043368230.186
b cell proliferationGO:0042100530.185
somatic recombination of immunoglobulin gene segmentsGO:0016447420.185
positive regulation of cellular amine metabolic processGO:003324050.184
macromolecule methylationGO:00434141200.176
regulation of protein secretionGO:0050708820.176
maintenance of locationGO:0051235890.175
cellular amine metabolic processGO:0044106440.175
regulation of defense responseGO:00313472330.174
somatic cell dna recombinationGO:0016444510.172
t helper 17 type immune responseGO:007253890.171
innate immune responseGO:00450871570.167
Mouse
regulation of monocyte extravasationGO:200043720.166
immunoglobulin productionGO:0002377730.164
lymphocyte homeostasisGO:0002260640.162
negative regulation of lymphocyte activationGO:0051250910.162
Mouse
defense response to virusGO:0051607680.161
Mouse
positive regulation of lymphocyte proliferationGO:0050671700.160
germinal center formationGO:0002467160.158
regulation of cellular amino acid metabolic processGO:000652150.156
regulation of cytokine secretionGO:0050707610.154
regulation of type 2 immune responseGO:0002828180.150
regulation of response to woundingGO:19030341890.149
regulation of cytokine productionGO:00018172660.147
Human Mouse
regulation of t cell activationGO:00508631700.146
Mouse
alpha beta t cell lineage commitmentGO:000236370.144
positive regulation of b cell activationGO:0050871490.142
phagocytosisGO:0006909660.142
Mouse
cation transportGO:00068123990.141
regulation of t cell proliferationGO:0042129920.139
Mouse
regulation of lymphocyte differentiationGO:00456191070.138
Mouse
positive regulation of inflammatory responseGO:0050729470.133
lymphocyte apoptotic processGO:0070227540.131
positive regulation of t cell differentiationGO:0045582520.131
regulation of adaptive immune responseGO:0002819900.126
regulation of apoptotic signaling pathwayGO:20012331970.126
regulation of map kinase activityGO:00434051200.125
cell type specific apoptotic processGO:00972852680.124
response to molecule of bacterial originGO:00022371430.124
Mouse
neuronal action potentialGO:0019228540.123
covalent chromatin modificationGO:00165691630.123
negative regulation of cellular protein metabolic processGO:00322692470.122
regulation of kinase activityGO:00435492490.121
helper t cell chemotaxisGO:003570410.121
immune complex clearanceGO:000243420.120
calcium ion transportGO:00068161590.119
cellular homeostasisGO:00197252400.119
interferon gamma productionGO:0032609670.119
Mouse
negative regulation of response to woundingGO:1903035770.119
histone h4 acetylationGO:0043967100.118
response to extracellular stimulusGO:00099911270.118
interleukin 2 productionGO:0032623330.117
Human
response to protozoanGO:0001562280.117
chromatin organizationGO:00063252060.116
chromatin modificationGO:00165681870.115
release of sequestered calcium ion into cytosolGO:0051209420.114
myd88 independent toll like receptor signaling pathwayGO:000275630.113
Mouse
antigen processing and presentationGO:0019882470.113
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.112
positive regulation of t cell proliferationGO:0042102520.111
positive regulation of cell developmentGO:00107202370.111
negative regulation of t cell differentiationGO:0045581230.111
Mouse
regulation of neutrophil differentiationGO:004565820.109
epidermis developmentGO:00085441870.108
Mouse
positive regulation of protein serine threonine kinase activityGO:00719021060.108
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.107
isotype switchingGO:0045190360.106
positive regulation of alpha beta t cell activationGO:0046635390.106
striated muscle tissue developmentGO:00147062930.104
regulation of secretion by cellGO:19035302490.102
response to peptideGO:19016521360.101
negative regulation of immune effector processGO:0002698550.101
Mouse
protein methylationGO:0006479810.101
negative regulation of defense responseGO:0031348770.101
Mouse
sequestering of metal ionGO:0051238190.100
lipopolysaccharide mediated signaling pathwayGO:0031663250.100
Mouse
cytokine mediated signaling pathwayGO:00192211150.099
Mouse
myeloid leukocyte activationGO:0002274830.098
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.097
regulation of bindingGO:00510981110.096
cation homeostasisGO:00550802120.096
regulation of interleukin 6 productionGO:0032675550.094
alpha beta t cell proliferationGO:0046633210.093
Mouse
t helper 2 cell differentiationGO:0045064120.093
regulation of mapk cascadeGO:00434082480.092
tissue remodelingGO:00487711020.092
negative regulation of phosphorus metabolic processGO:00105631840.091
t cell differentiation in thymusGO:0033077770.091
cytokine production involved in immune responseGO:0002367340.090
interleukin 12 secretionGO:007261030.089
cellular chemical homeostasisGO:00550822150.089
mature dendritic cell differentiationGO:009702930.088
divalent inorganic cation homeostasisGO:00725071380.087
positive regulation of innate immune responseGO:0045089800.085
protein alkylationGO:0008213810.084
cellular response to external stimulusGO:0071496880.084
b cell differentiationGO:0030183780.083
epithelial tube morphogenesisGO:00605623030.082
positive regulation of kinase activityGO:00336741550.082
regulation of epithelial cell proliferationGO:00506781410.081
cellular response to extracellular stimulusGO:0031668810.080
t helper cell lineage commitmentGO:000229560.080
cellular lipid metabolic processGO:00442553230.079
histone acetylationGO:0016573410.078
negative regulation of growth of symbiont in hostGO:0044130190.077
Mouse
leukocyte apoptotic processGO:0071887710.076
gliogenesisGO:00420631410.076
regulation of protein kinase activityGO:00458592320.076
regulation of interleukin 2 productionGO:0032663280.076
Human
protein secretionGO:00093061110.075
regulation of response to biotic stimulusGO:0002831380.075
Mouse
positive regulation of hydrolase activityGO:00513451480.075
cellular calcium ion homeostasisGO:00068741190.074
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.074
monocyte extravasationGO:003569620.074
wound healingGO:00420601570.074
positive regulation of cytokine secretionGO:0050715410.073
sensory perceptionGO:00076002450.073
positive regulation of b cell proliferationGO:0030890240.073
positive regulation of adaptive immune responseGO:0002821610.073
divalent inorganic cation transportGO:00725111780.072
positive regulation of t cell receptor signaling pathwayGO:005086240.072
defense response to bacteriumGO:00427421190.072
Mouse
regulation of tumor necrosis factor biosynthetic processGO:0042534100.072
positive regulation of map kinase activityGO:0043406840.071
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.071
interleukin 5 secretionGO:007260320.070
regulation of stress activated mapk cascadeGO:0032872690.070
neuron apoptotic processGO:00514021420.069
regulation of t cell differentiationGO:0045580830.069
Mouse
regulation of cellular response to stressGO:00801351590.069
reactive oxygen species metabolic processGO:0072593840.069
type 2 immune responseGO:0042092230.069
toll like receptor signaling pathwayGO:0002224380.068
neutrophil differentiationGO:003022330.068
pattern recognition receptor signaling pathwayGO:0002221470.068
interferon beta biosynthetic processGO:004535040.068
Mouse
positive regulation of leukocyte apoptotic processGO:2000108210.068
extracellular matrix organizationGO:00301981470.068
somatic diversification of immune receptorsGO:0002200530.067
regulation of inflammatory responseGO:00507271470.067
sensory organ morphogenesisGO:00905962420.066
immunoglobulin secretionGO:0048305170.065
regulation of myeloid cell differentiationGO:0045637960.065
regulation of transferase activityGO:00513382630.065
cellular divalent inorganic cation homeostasisGO:00725031270.065
negative regulation of lymphocyte proliferationGO:0050672450.064
synaptic transmissionGO:00072683290.064
negative regulation of protein modification processGO:00314001630.063
regulation of leukocyte apoptotic processGO:2000106560.063
neuron deathGO:00709971540.063
purine nucleoside metabolic processGO:00422782410.062
divalent metal ion transportGO:00708381720.062
negative regulation of molecular functionGO:00440922580.062
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.062
monosaccharide metabolic processGO:00059961060.062
positive regulation of protein modification processGO:00314012990.062
glycosyl compound catabolic processGO:19016582060.062
glycoprotein biosynthetic processGO:0009101890.062
regulation of interleukin 1 productionGO:0032652260.062
regulation of gtp catabolic processGO:00331241130.061
transmission of nerve impulseGO:0019226760.061
regulation of b cell mediated immunityGO:0002712370.060
negative regulation of apoptotic signaling pathwayGO:20012341040.060
nucleoside catabolic processGO:00091642060.059
antigen receptor mediated signaling pathwayGO:0050851640.059
carbohydrate metabolic processGO:00059752300.059
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.059
positive regulation of programmed cell deathGO:00430682180.058
positive regulation of dendritic cell chemotaxisGO:200051010.058
organic acid transportGO:00158491010.058
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026150.057
Mouse
cerebral cortex developmentGO:0021987860.057
regulation of homeostatic processGO:00328441820.057
positive regulation of gtp catabolic processGO:0033126850.057
gland developmentGO:00487323300.056
Mouse
positive regulation of secretion by cellGO:19035321140.056
regulation of myd88 independent toll like receptor signaling pathwayGO:003412710.056
Mouse
regulation of vesicle mediated transportGO:00606271390.056
positive regulation of immunological synapse formationGO:200052210.055
regulation of interleukin 8 productionGO:003267730.054
calcium ion homeostasisGO:00550741270.054
t helper 2 cell cytokine productionGO:003574540.053
symbiosis encompassing mutualism through parasitismGO:0044403830.053
Mouse
membrane organizationGO:00610242450.053
programmed necrotic cell deathGO:0097300280.053
Mouse
interspecies interaction between organismsGO:0044419830.053
Mouse
mapk cascadeGO:00001652810.053
growth involved in symbiotic interactionGO:0044110230.053
Mouse
organic cyclic compound catabolic processGO:19013612950.052
multicellular organismal signalingGO:0035637910.052
organophosphate catabolic processGO:00464342320.052
guanosine containing compound metabolic processGO:19010681440.052
skeletal muscle fiber developmentGO:0048741580.052
positive regulation of apoptotic signaling pathwayGO:2001235950.051
regulation of secretionGO:00510462740.051
purine nucleoside triphosphate metabolic processGO:00091442260.051
purine nucleotide metabolic processGO:00061633020.051
carbohydrate derivative catabolic processGO:19011362310.050
g protein coupled receptor signaling pathwayGO:00071862430.050
heterocycle catabolic processGO:00467002800.050
response to organic cyclic compoundGO:00140701980.050
Mouse
gtp metabolic processGO:00460391440.050
developmental programmed cell deathGO:0010623410.050
regulation of cell motilityGO:20001452360.049
regulation of protein transportGO:00512231630.049
glycosyl compound metabolic processGO:19016572460.049
nucleoside triphosphate metabolic processGO:00091412300.049
regulation of cd4 positive alpha beta t cell activationGO:2000514240.048
positive regulation of neuron differentiationGO:00456661410.048
regulation of cytokine production involved in immune responseGO:0002718260.048
small gtpase mediated signal transductionGO:0007264970.048
positive regulation of bindingGO:0051099490.048
positive regulation of immune effector processGO:00026991070.048
dna damage response signal transduction by p53 class mediatorGO:0030330190.047
negative regulation of cytokine productionGO:0001818840.047
Mouse
positive regulation of transferase activityGO:00513471670.047
negative thymic t cell selectionGO:0045060120.047
leukocyte homeostasisGO:0001776790.047
negative regulation of cellular amine metabolic processGO:003323910.047
regulation of lymphocyte mediated immunityGO:0002706840.047
cellular response to dna damage stimulusGO:00069742070.047
bone resorptionGO:0045453380.047
carboxylic acid transportGO:00469421000.047
peptidyl lysine modificationGO:0018205770.047
anion transportGO:00068201770.047
negative regulation of synapse assemblyGO:005196430.046
negative regulation of homeostatic processGO:0032845710.046
action potentialGO:0001508780.046
nucleoside triphosphate catabolic processGO:00091432050.046
positive regulation of secretionGO:00510471300.046
nucleotide metabolic processGO:00091173320.046
ensheathment of neuronsGO:0007272760.046
posttranscriptional regulation of gene expressionGO:00106081550.046
aromatic compound catabolic processGO:00194392860.045
thymic t cell selectionGO:0045061220.045
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.045
cytosolic calcium ion transportGO:0060401480.045
positive regulation of t cell costimulationGO:200052520.045
ribonucleoside catabolic processGO:00424542060.044
cellular nitrogen compound catabolic processGO:00442702800.044
multicellular organismal homeostasisGO:00488711640.044
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.044
lipid transportGO:0006869980.044
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.043
stem cell differentiationGO:00488632680.043
alcohol metabolic processGO:00060661160.043
skeletal muscle organ developmentGO:00605381630.043
plasma membrane organizationGO:0007009900.043
positive regulation of production of molecular mediator of immune responseGO:0002702450.042
negative regulation of interferon beta productionGO:003268830.042
Mouse
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.042
Mouse
ras protein signal transductionGO:0007265770.042
positive regulation of ion transportGO:0043270650.042
internal peptidyl lysine acetylationGO:0018393420.042
regulation of peptidase activityGO:0052547960.042
negative regulation of toll like receptor signaling pathwayGO:0034122140.042
immune response regulating cell surface receptor signaling pathwayGO:0002768800.041
sequestering of calcium ionGO:0051208180.041
positive regulation of response to woundingGO:1903036660.041
positive regulation of lymphocyte differentiationGO:0045621610.041
microglia differentiationGO:001400420.040
regulation of interleukin 10 secretionGO:200117940.040
purine ribonucleoside metabolic processGO:00461282410.040
stress activated mapk cascadeGO:0051403800.040
negative regulation of cellular amino acid metabolic processGO:004576300.040
regulation of interleukin 12 biosynthetic processGO:004507580.040
Mouse
regulation of antigen receptor mediated signaling pathwayGO:0050854290.040
regulation of ion homeostasisGO:2000021640.040
regulation of leukocyte mediated immunityGO:00027031040.040
purine containing compound metabolic processGO:00725213110.039
morphogenesis of a branching epitheliumGO:00611381930.039
macrophage activationGO:0042116270.039
protein processingGO:00164851630.039
nucleoside phosphate metabolic processGO:00067533380.039
fatty acid metabolic processGO:00066311210.039
positive regulation of t cell extravasationGO:200040920.039
positive regulation of apoptotic processGO:00430652170.039
cellular protein catabolic processGO:00442571550.039
regulation of ion transportGO:00432692150.038
negative regulation of interleukin 13 productionGO:003269620.038
purine ribonucleotide catabolic processGO:00091542080.038
organic hydroxy compound metabolic processGO:19016152030.038
negative regulation of growthGO:0045926990.038
Mouse
positive regulation of lymphocyte mediated immunityGO:0002708620.038
regulation of anatomical structure sizeGO:00900661780.038
brown fat cell differentiationGO:0050873360.037
branching morphogenesis of an epithelial tubeGO:00487541590.037
phosphatidylinositol 3 kinase signalingGO:0014065360.037
eosinophil activationGO:004330710.037
protein maturationGO:00516041760.037
negative regulation of t helper 2 cell differentiationGO:004562940.037
extracellular structure organizationGO:00430621480.037
regulation of regulatory t cell differentiationGO:004558970.037
Mouse
activation of immune responseGO:00022531380.037
molting cycleGO:0042303900.036
regulation of multi organism processGO:00439001110.036
Mouse
regulation of eosinophil degranulationGO:004330910.036
negative regulation of lymphocyte differentiationGO:0045620320.036
Mouse
regulation of metal ion transportGO:00109591060.036
dephosphorylationGO:00163111290.036
response to organonitrogen compoundGO:00102432460.036
jnk cascadeGO:0007254720.036
macromolecule catabolic processGO:00090572810.036
membrane lipid biosynthetic processGO:0046467320.036
positive regulation of cell migrationGO:00303351090.036
natural killer cell activationGO:0030101440.036
negative regulation of multi organism processGO:0043901680.036
Mouse
positive regulation of interleukin 2 productionGO:0032743190.035
Human
regulation of defense response to virusGO:0050688180.035
Mouse
cellular response to organonitrogen compoundGO:00714171450.035
regulation of cellular catabolic processGO:00313292420.035
positive regulation of interferon gamma productionGO:0032729390.035
Mouse
fat cell differentiationGO:00454441600.034
positive regulation of mapk cascadeGO:00434101700.034
germ cell developmentGO:00072811850.034
myelinationGO:0042552740.034
eosinophil mediated immunityGO:000244710.034
regulation of hydrolase activityGO:00513362460.033
cellular ion homeostasisGO:00068731650.033
b cell apoptotic processGO:0001783190.033
regulation of body fluid levelsGO:00508781620.033
dna modificationGO:0006304500.033
regulation of interleukin 13 secretionGO:200066520.033
regulation of interleukin 2 biosynthetic processGO:0045076130.033
Human
immune response regulating signaling pathwayGO:00027641250.033
regulation of reactive oxygen species metabolic processGO:2000377400.032
positive regulation of interleukin 8 secretionGO:200048410.032
regulation of protein localizationGO:00328802310.032
muscle tissue developmentGO:00605373080.032
negative regulation of phosphorylationGO:00423261660.032
negative regulation of eosinophil degranulationGO:004331010.032
cytoplasmic transportGO:00164822340.032
eosinophil activation involved in immune responseGO:000227810.032
response to type i interferonGO:0034340120.032
Mouse
response to nutrient levelsGO:00316671090.032
ribose phosphate metabolic processGO:00196932910.032
peptidyl serine modificationGO:0018209830.032
blood vessel morphogenesisGO:00485142850.032
hair follicle developmentGO:0001942850.032
cellular macromolecule catabolic processGO:00442652060.032
ameboidal type cell migrationGO:00016671280.032
positive regulation of jnk cascadeGO:0046330460.031
regulation of hormone levelsGO:00108172110.031
cell adhesionGO:00071553290.031
signal transduction by p53 class mediatorGO:0072331510.031
innate immune response activating signal transductionGO:0002758500.031
cellular response to hormone stimulusGO:00328701500.031
organic anion transportGO:00157111370.031
negative regulation of interleukin 10 secretionGO:200118020.031
nucleoside metabolic processGO:00091162460.031
regulation of purine nucleotide catabolic processGO:00331211220.031
ion transmembrane transportGO:00342203610.031
nephron developmentGO:00720061090.031
epithelial cell proliferationGO:00506731740.031
Mouse
apoptotic process involved in developmentGO:1902742280.031
stem cell developmentGO:00488642190.030
exocytosisGO:00068871210.030
circadian rhythmGO:00076231140.030
camera type eye developmentGO:00430102660.030
monocarboxylic acid metabolic processGO:00327871910.030
glial cell apoptotic processGO:003434930.030
regulation of neuron differentiationGO:00456642810.030
female gamete generationGO:0007292740.030
positive regulation of protein phosphorylationGO:00019342420.030
sphingolipid biosynthetic processGO:0030148260.030
myotube differentiationGO:00149021050.030
regulation of interleukin 1 beta secretionGO:0050706150.030
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.030
intracellular protein transportGO:00068862040.030
regulation of protein maturationGO:1903317960.030
steroid metabolic processGO:00082021190.030
cell growthGO:00160491300.030
b cell receptor signaling pathwayGO:0050853200.030
histone modificationGO:00165701590.029
interleukin 12 biosynthetic processGO:004209080.029
Mouse
regulation of cd8 positive alpha beta t cell activationGO:200118530.029
Mouse
rho protein signal transductionGO:0007266320.029
oxidation reduction processGO:00551143420.029
positive regulation of leukocyte differentiationGO:1902107860.029
regulation of interleukin 5 secretionGO:200066220.029
negative regulation of myeloid leukocyte differentiationGO:0002762200.029

Irf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.171
disease of anatomical entityDOID:700.171
musculoskeletal system diseaseDOID:1700.049
connective tissue diseaseDOID:6500.047
hematopoietic system diseaseDOID:7400.045
primary immunodeficiency diseaseDOID:61200.043
blood protein diseaseDOID:62000.038
agammaglobulinemiaDOID:258300.038
common variable immunodeficiencyDOID:1217700.038
b cell deficiencyDOID:211500.038