Mus musculus

167 known processes

Irf8

interferon regulatory factor 8

(Aliases: Icsbp1,IRF-8,ICSBP,AI893568,Myls)

Irf8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
adaptive immune responseGO:00022501550.938
Mouse
immune response activating signal transductionGO:00027571160.926
Mouse
lymphocyte differentiationGO:00300982420.926
Mouse
regulation of myd88 independent toll like receptor signaling pathwayGO:003412710.789
Mouse
lymphocyte mediated immunityGO:00024491390.781
Mouse
negative regulation of protein metabolic processGO:00512482820.737
Mouse
t cell activationGO:00421102890.736
Mouse
leukocyte proliferationGO:00706611720.729
Mouse
b cell activationGO:00421131610.710
lymphocyte proliferationGO:00466511640.642
Mouse
negative regulation of phosphorus metabolic processGO:00105631840.621
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.621
Mouse
cd8 positive alpha beta t cell proliferationGO:003574010.617
Mouse
t cell differentiationGO:00302171740.603
Mouse
activation of immune responseGO:00022531380.588
Mouse
regulation of leukocyte proliferationGO:00706631210.564
Mouse
alpha beta t cell differentiationGO:0046632690.562
Mouse
leukocyte mediated immunityGO:00024431740.560
Mouse
negative regulation of cellular amine metabolic processGO:003323910.557
regulation of t cell differentiationGO:0045580830.555
Mouse
response to interferon gammaGO:0034341340.548
Mouse
leukocyte differentiationGO:00025213420.524
Mouse
negative regulation of leukocyte differentiationGO:1902106510.519
Mouse
negative regulation of immune system processGO:00026832090.513
Mouse
t cell proliferationGO:00420981200.510
Mouse
positive regulation of lymphocyte activationGO:00512511400.503
regulation of b cell activationGO:0050864810.502
amine metabolic processGO:0009308450.499
cellular response to interferon gammaGO:0071346250.487
Mouse
actin cytoskeleton organizationGO:00300362200.484
regulation of cell activationGO:00508652890.456
Mouse
regulation of cellular ketone metabolic processGO:0010565660.455
negative regulation of protein modification processGO:00314001630.446
alpha beta t cell activationGO:0046631910.440
Mouse
regulation of b cell differentiationGO:0045577230.404
immune response regulating signaling pathwayGO:00027641250.396
Mouse
gland developmentGO:00487323300.393
Mouse
metal ion homeostasisGO:00550651890.385
positive regulation of lymphocyte differentiationGO:0045621610.381
antigen receptor mediated signaling pathwayGO:0050851640.378
b cell differentiationGO:0030183780.377
cation transportGO:00068123990.373
homeostasis of number of cellsGO:00488722100.365
cellular ketone metabolic processGO:0042180840.357
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.353
positive regulation of leukocyte proliferationGO:0070665730.337
leukocyte activation involved in immune responseGO:00023661260.334
Mouse
positive regulation of leukocyte differentiationGO:1902107860.323
regulation of lymphocyte proliferationGO:00506701170.320
Mouse
covalent chromatin modificationGO:00165691630.316
Mouse
immune effector processGO:00022523210.311
Mouse
positive regulation of adaptive immune responseGO:0002821610.310
regulation of lymphocyte activationGO:00512492400.307
Mouse
cellular metal ion homeostasisGO:00068751510.302
t cell selectionGO:0045058340.302
Mouse
negative regulation of protein serine threonine kinase activityGO:0071901490.298
response to lipopolysaccharideGO:00324961280.292
organonitrogen compound catabolic processGO:19015652640.280
regulation of protein kinase activityGO:00458592320.275
skin developmentGO:00435882200.274
Mouse
negative regulation of phosphorylationGO:00423261660.273
cellular ion homeostasisGO:00068731650.267
regulation of leukocyte differentiationGO:19021051590.258
Mouse
regulation of cell cycleGO:00517262810.257
immune response activating cell surface receptor signaling pathwayGO:0002429720.252
negative regulation of protein phosphorylationGO:00019331260.252
hematopoietic progenitor cell differentiationGO:00022441430.249
negative regulation of phosphate metabolic processGO:00459361840.247
regulation of t cell activationGO:00508631700.244
Mouse
cell adhesionGO:00071553290.243
cytokine mediated signaling pathwayGO:00192211150.242
Mouse
negative regulation of lymphocyte activationGO:0051250910.242
Mouse
positive regulation of cell developmentGO:00107202370.241
regulation of lymphocyte differentiationGO:00456191070.239
Mouse
positive regulation of protein modification processGO:00314012990.238
myeloid cell homeostasisGO:00022621140.238
positive regulation of t cell differentiationGO:0045582520.237
regulation of cell adhesionGO:00301551540.235
defense response to protozoanGO:0042832250.230
cellular chemical homeostasisGO:00550822150.230
negative regulation of cell proliferationGO:00082852960.229
Mouse
nucleobase containing small molecule metabolic processGO:00550863520.227
cellular amine metabolic processGO:0044106440.218
negative regulation of cellular amino acid metabolic processGO:004576300.216
actin filament organizationGO:00070151130.215
positive regulation of programmed cell deathGO:00430682180.213
regulation of cellular amino acid metabolic processGO:000652150.213
purine ribonucleoside triphosphate catabolic processGO:00092071990.213
calcium ion transportGO:00068161590.212
positive regulation of kinase activityGO:00336741550.211
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.210
negative regulation of toll like receptor signaling pathwayGO:0034122140.209
Mouse
positive regulation of cell deathGO:00109422240.208
negative regulation of defense response to virus by hostGO:005068910.207
Mouse
proteolysis involved in cellular protein catabolic processGO:00516031470.200
epidermis developmentGO:00085441870.199
Mouse
cellular amino acid metabolic processGO:00065201030.197
b cell homeostasisGO:0001782340.196
extrinsic apoptotic signaling pathwayGO:00971911260.192
organelle assemblyGO:00709251770.191
negative regulation of cellular protein metabolic processGO:00322692470.188
innate immune responseGO:00450871570.185
Mouse
regulation of cellular amine metabolic processGO:0033238200.180
cellular homeostasisGO:00197252400.177
antigen processing and presentation of exogenous peptide antigenGO:0002478210.176
negative regulation of t cell differentiationGO:0045581230.173
Mouse
antigen processing and presentationGO:0019882470.168
t cell differentiation in thymusGO:0033077770.167
cellular response to molecule of bacterial originGO:0071219830.167
purine ribonucleoside triphosphate metabolic processGO:00092052200.166
lymphocyte homeostasisGO:0002260640.162
positive regulation of organelle organizationGO:00106381280.160
positive regulation of interferon alpha productionGO:003272740.160
Mouse
regulation of organelle organizationGO:00330432890.159
positive regulation of t cell activationGO:00508701010.155
positive regulation of cellular amine metabolic processGO:003324050.154
peptidyl amino acid modificationGO:00181933360.154
Mouse
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.153
glycosyl compound catabolic processGO:19016582060.152
b cell receptor signaling pathwayGO:0050853200.152
regulation of response to biotic stimulusGO:0002831380.152
Mouse
cell chemotaxisGO:0060326810.151
nucleoside triphosphate catabolic processGO:00091432050.150
response to organic cyclic compoundGO:00140701980.149
Mouse
regulation of myd88 dependent toll like receptor signaling pathwayGO:003412420.149
Mouse
purine nucleoside metabolic processGO:00422782410.145
cell substrate adhesionGO:00315891300.144
leukocyte mediated cytotoxicityGO:0001909620.143
chromatin organizationGO:00063252060.142
Mouse
multicellular organism growthGO:00352641610.142
release of sequestered calcium ion into cytosolGO:0051209420.142
positive regulation of type i interferon mediated signaling pathwayGO:006034040.141
Mouse
negative regulation of kinase activityGO:0033673810.140
b cell proliferationGO:0042100530.140
stem cell differentiationGO:00488632680.140
organic cyclic compound catabolic processGO:19013612950.140
negative regulation of lymphocyte differentiationGO:0045620320.139
Mouse
lipopolysaccharide mediated signaling pathwayGO:0031663250.139
Mouse
ribonucleoside catabolic processGO:00424542060.137
regulation of transferase activityGO:00513382630.137
epithelial tube morphogenesisGO:00605623030.137
regulation of adaptive immune responseGO:0002819900.136
myeloid leukocyte activationGO:0002274830.134
Mouse
positive regulation of cell activationGO:00508671580.133
positive t cell selectionGO:0043368230.132
Mouse
b cell mediated immunityGO:0019724710.132
Mouse
regulation of neutrophil differentiationGO:004565820.132
protein localization to organelleGO:00333651850.130
negative regulation of cell activationGO:00508661110.129
Mouse
columnar cuboidal epithelial cell differentiationGO:0002065820.128
programmed necrotic cell deathGO:0097300280.128
Mouse
morphogenesis of a branching structureGO:00017632030.128
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.127
Mouse
central nervous system neuron differentiationGO:00219531620.126
glycosyl compound metabolic processGO:19016572460.126
antigen processing and presentation of peptide antigenGO:0048002290.126
purine ribonucleotide metabolic processGO:00091502900.125
ribonucleoside triphosphate metabolic processGO:00091992200.125
response to organonitrogen compoundGO:00102432460.124
cellular calcium ion homeostasisGO:00068741190.123
purine nucleoside triphosphate metabolic processGO:00091442260.122
regulation of kinase activityGO:00435492490.121
positive regulation of hydrolase activityGO:00513451480.120
aromatic compound catabolic processGO:00194392860.119
dephosphorylationGO:00163111290.118
muscle cell differentiationGO:00426922610.118
apoptotic signaling pathwayGO:00971903060.116
purine nucleoside triphosphate catabolic processGO:00091462030.115
carbohydrate derivative catabolic processGO:19011362310.115
regulation of cellular component sizeGO:00325351210.114
positive regulation of cellular amino acid metabolic processGO:004576430.113
posttranscriptional regulation of gene expressionGO:00106081550.112
cellular response to growth factor stimulusGO:00713631970.112
defense response to bacteriumGO:00427421190.111
cd4 positive alpha beta t cell activationGO:0035710450.110
Mouse
ribose phosphate metabolic processGO:00196932910.109
t helper cell differentiationGO:0042093280.109
Mouse
divalent inorganic cation homeostasisGO:00725071380.109
developmental maturationGO:00217001930.108
regulation of metal ion transportGO:00109591060.107
interspecies interaction between organismsGO:0044419830.106
axonogenesisGO:00074092740.106
macromolecule methylationGO:00434141200.106
Mouse
symbiosis encompassing mutualism through parasitismGO:0044403830.105
regulation of t cell proliferationGO:0042129920.104
Mouse
cytoplasmic transportGO:00164822340.104
divalent metal ion transportGO:00708381720.104
nucleoside catabolic processGO:00091642060.103
glycoprotein metabolic processGO:00091001160.102
reactive oxygen species metabolic processGO:0072593840.102
maintenance of locationGO:0051235890.101
erythrocyte differentiationGO:0030218880.101
regulation of actin filament based processGO:0032970990.100
purine ribonucleotide catabolic processGO:00091542080.100
molting cycleGO:0042303900.100
positive regulation of apoptotic processGO:00430652170.098
regulation of neuron apoptotic processGO:00435231220.098
t cell receptor signaling pathwayGO:0050852460.098
regulation of apoptotic signaling pathwayGO:20012331970.098
sequestering of metal ionGO:0051238190.095
cytokine biosynthetic processGO:0042089680.095
Mouse
regulation of protein complex assemblyGO:0043254830.094
purine containing compound metabolic processGO:00725213110.094
single organism cell adhesionGO:00986021560.094
lymphocyte apoptotic processGO:0070227540.093
ribonucleoside metabolic processGO:00091192450.093
cytosolic calcium ion transportGO:0060401480.092
defense response to virusGO:0051607680.091
Mouse
positive regulation of protein kinase activityGO:00458601440.089
regulation of innate immune responseGO:0045088910.089
Mouse
cellular lipid metabolic processGO:00442553230.089
angiogenesisGO:00015252010.089
necrotic cell deathGO:0070265300.088
Mouse
phagocytosisGO:0006909660.088
b cell apoptotic processGO:0001783190.088
leukocyte homeostasisGO:0001776790.087
regulation of homeostatic processGO:00328441820.087
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.086
cellular response to organonitrogen compoundGO:00714171450.086
forebrain developmentGO:00309003020.085
purine ribonucleoside metabolic processGO:00461282410.085
keratinocyte differentiationGO:0030216480.084
Mouse
ras protein signal transductionGO:0007265770.084
ribonucleoside triphosphate catabolic processGO:00092031990.084
cellular response to hormone stimulusGO:00328701500.084
female sex differentiationGO:0046660840.084
nucleotide catabolic processGO:00091662170.083
calcium ion homeostasisGO:00550741270.083
negative regulation of cellular component organizationGO:00511291940.083
regulation of purine nucleotide metabolic processGO:19005421690.082
cellular macromolecule catabolic processGO:00442652060.082
regulation of membrane potentialGO:00423911920.082
positive regulation of gtp catabolic processGO:0033126850.082
immune response regulating cell surface receptor signaling pathwayGO:0002768800.082
immunoglobulin mediated immune responseGO:0016064690.081
Mouse
morphogenesis of a branching epitheliumGO:00611381930.081
response to hypoxiaGO:0001666580.081
positive regulation of cellular component biogenesisGO:0044089940.080
pyrimidine containing compound catabolic processGO:007252930.080
response to ionizing radiationGO:0010212420.080
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.080
Mouse
regulation of interleukin 4 biosynthetic processGO:004540230.080
negative regulation of b cell activationGO:0050869270.079
cell activation involved in immune responseGO:00022631260.079
Mouse
rho protein signal transductionGO:0007266320.079
regulation of leukocyte apoptotic processGO:2000106560.079
purine nucleotide catabolic processGO:00061952110.078
myeloid dendritic cell differentiationGO:0043011160.077
Mouse
cytosolic calcium ion homeostasisGO:0051480700.077
sensory organ morphogenesisGO:00905962420.076
protein methylationGO:0006479810.076
Mouse
cellular response to biotic stimulusGO:0071216920.076
nucleoside triphosphate metabolic processGO:00091412300.076
negative regulation of cytokine productionGO:0001818840.074
Mouse
positive regulation of apoptotic signaling pathwayGO:2001235950.074
regulation of b cell apoptotic processGO:0002902130.074
guanosine containing compound metabolic processGO:19010681440.074
cell fate commitmentGO:00451652100.073
Mouse
germ cell developmentGO:00072811850.073
camera type eye developmentGO:00430102660.073
organic hydroxy compound metabolic processGO:19016152030.073
renal system developmentGO:00720012250.072
erk1 and erk2 cascadeGO:0070371770.072
cellular response to extracellular stimulusGO:0031668810.072
negative regulation of homeostatic processGO:0032845710.072
positive regulation of cell motilityGO:20001471160.071
tissue homeostasisGO:00018941150.071
regulation of defense responseGO:00313472330.071
Mouse
small gtpase mediated signal transductionGO:0007264970.071
dna metabolic processGO:00062593030.071
regulation of lymphocyte apoptotic processGO:0070228410.070
response to oxygen levelsGO:0070482620.070
negative regulation of myeloid cell differentiationGO:0045638380.070
regulation of striated muscle cell differentiationGO:0051153810.070
negative regulation of lymphocyte proliferationGO:0050672450.070
cation homeostasisGO:00550802120.069
calcium ion transport into cytosolGO:0060402480.069
organophosphate catabolic processGO:00464342320.069
regulation of ion transportGO:00432692150.068
regulation of cell growthGO:0001558910.068
positive regulation of smooth muscle cell migrationGO:001491140.068
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.068
cytokine secretionGO:0050663720.068
peptidyl lysine modificationGO:0018205770.068
Mouse
tissue remodelingGO:00487711020.067
regulation of cell shapeGO:0008360390.067
t cell mediated immunityGO:0002456500.067
cell type specific apoptotic processGO:00972852680.067
myd88 independent toll like receptor signaling pathwayGO:000275630.066
Mouse
rhythmic processGO:00485111740.066
negative regulation of regulatory t cell differentiationGO:004559020.066
Mouse
muscle cell migrationGO:0014812190.065
regulation of ras protein signal transductionGO:00465781140.065
positive regulation of purine nucleotide catabolic processGO:0033123880.065
regulation of myeloid cell differentiationGO:0045637960.065
regulation of bindingGO:00510981110.065
Mouse
b cell activation involved in immune responseGO:0002312500.065
male gamete generationGO:00482322850.064
regulation of erythrocyte differentiationGO:0045646230.064
positive regulation of defense responseGO:00313491240.064
Mouse
ear developmentGO:00435832000.064
branching involved in mammary gland duct morphogenesisGO:0060444270.064
heterocycle catabolic processGO:00467002800.063
germinal center formationGO:0002467160.063
t cell activation involved in immune responseGO:0002286430.063
Mouse
axon guidanceGO:00074111410.063
internal protein amino acid acetylationGO:0006475420.063
Mouse
regulation of hormone levelsGO:00108172110.063
nucleotide metabolic processGO:00091173320.062
response to molecule of bacterial originGO:00022371430.062
response to amino acidGO:0043200370.062
regulation of b cell proliferationGO:0030888390.062
nk t cell differentiationGO:000186580.062
anatomical structure homeostasisGO:00602491450.061
lymphocyte activation involved in immune responseGO:0002285930.061
Mouse
positive regulation of cytokine productionGO:00018191740.061
cellular response to cytokine stimulusGO:00713451890.061
Mouse
myeloid cell differentiationGO:00300992330.061
sequestering of calcium ionGO:0051208180.061
glomerulus developmentGO:0032835400.060
positive regulation of b cell proliferationGO:0030890240.060
regulation of epithelial cell proliferationGO:00506781410.060
positive regulation of erk1 and erk2 cascadeGO:0070374470.059
gtp metabolic processGO:00460391440.059
alpha beta t cell lineage commitmentGO:000236370.059
Mouse
regulation of actin cytoskeleton organizationGO:0032956840.059
regulation of anatomical structure sizeGO:00900661780.059
cell maturationGO:00484691270.059
positive regulation of protein phosphorylationGO:00019342420.059
regulation of alpha beta t cell differentiationGO:0046637350.058
positive regulation of innate immune responseGO:0045089800.058
Mouse
regulation of gtp catabolic processGO:00331241130.058
regulation of alpha beta t cell proliferationGO:0046640180.057
Mouse
negative regulation of organelle organizationGO:0010639900.057
neuron apoptotic processGO:00514021420.057
response to transforming growth factor betaGO:0071559880.057
leukocyte migrationGO:00509001240.057
response to peptideGO:19016521360.057
ribonucleotide metabolic processGO:00092592910.057
thymus developmentGO:0048538410.057
cellular response to lipopolysaccharideGO:0071222770.056
purine nucleoside catabolic processGO:00061522050.056
positive regulation of leukocyte apoptotic processGO:2000108210.056
branching morphogenesis of an epithelial tubeGO:00487541590.056
negative regulation of intracellular signal transductionGO:19025321670.056
production of molecular mediator of immune responseGO:00024401030.056
purine nucleotide metabolic processGO:00061633020.056
negative regulation of molecular functionGO:00440922580.056
positive regulation of mapk cascadeGO:00434101700.055
regulation of reactive oxygen species metabolic processGO:2000377400.055
ovulation cycleGO:0042698590.055
regulation of protein serine threonine kinase activityGO:00719001570.055
regulation of synaptic growth at neuromuscular junctionGO:000858240.055
membrane organizationGO:00610242450.055
regulation of myotube differentiationGO:0010830620.054
myotube differentiationGO:00149021050.054
protein autophosphorylationGO:0046777610.054
kidney developmentGO:00018222130.054
thymic t cell selectionGO:0045061220.053
pyrimidine nucleoside catabolic processGO:004613510.053
response to ethanolGO:0045471180.053
hormone metabolic processGO:0042445860.052
divalent inorganic cation transportGO:00725111780.051
muscle tissue developmentGO:00605373080.051
dendritic cell differentiationGO:0097028260.050
Mouse
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.050
Mouse
positive regulation of nervous system developmentGO:00519622210.050
regulation of intracellular transportGO:00323861590.050
viral life cycleGO:0019058360.050
developmental programmed cell deathGO:0010623410.050
alpha beta t cell differentiation involved in immune responseGO:0002293300.049
Mouse
chromatin modificationGO:00165681870.049
Mouse
regulation of nucleotide catabolic processGO:00308111220.049
histone acetylationGO:0016573410.049
Mouse
negative regulation of synapse assemblyGO:005196430.049
positive regulation of purine nucleotide metabolic processGO:19005441140.049
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026150.049
guanosine containing compound catabolic processGO:19010691440.049
response to acid chemicalGO:00011011110.049
regulation of cellular catabolic processGO:00313292420.048
regulation of mitotic cell cycle phase transitionGO:1901990730.048
regulation of interferon alpha productionGO:003264750.048
Mouse
positive thymic t cell selectionGO:0045059130.048
response to platelet derived growth factorGO:003611960.047
response to alcoholGO:0097305480.047
homotypic cell cell adhesionGO:0034109280.047
protein alkylationGO:0008213810.047
Mouse
regulation of neuron differentiationGO:00456642810.047
blood vessel morphogenesisGO:00485142850.047
positive regulation of map kinase activityGO:0043406840.047
viral processGO:0016032410.046
response to extracellular stimulusGO:00099911270.046
protein localization to nucleusGO:00345041210.046
regulation of purine nucleotide catabolic processGO:00331211220.045
cellular protein catabolic processGO:00442571550.045
t cell apoptotic processGO:0070231390.045
endocytosisGO:00068971680.045
positive regulation of protein complex assemblyGO:0031334450.045
cellular divalent inorganic cation homeostasisGO:00725031270.045
dna modificationGO:0006304500.045
response to peptide hormoneGO:00434341270.045
myeloid leukocyte differentiationGO:00025731190.044
Mouse
positive regulation of neuron differentiationGO:00456661410.044
regulation of germinal center formationGO:0002634100.044
positive regulation of protein serine threonine kinase activityGO:00719021060.044
nucleoside phosphate metabolic processGO:00067533380.044
multicellular organismal homeostasisGO:00488711640.043
positive regulation of phospholipase activityGO:001051830.043
glucose homeostasisGO:00425931280.043
cellular protein complex assemblyGO:00436231160.042
phosphatidylinositol 3 kinase signalingGO:0014065360.042
neuron projection guidanceGO:00974851410.042
response to drugGO:0042493750.042
positive regulation of alpha beta t cell differentiationGO:0046638280.042
response to oxidative stressGO:00069791230.042
digestive system developmentGO:00551232000.042
positive regulation of cell migrationGO:00303351090.042
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.042
metanephros developmentGO:0001656790.042
antigen processing and presentation of exogenous antigenGO:0019884260.042
ribonucleotide catabolic processGO:00092612080.042
carbohydrate metabolic processGO:00059752300.042
cd8 positive alpha beta t cell differentiationGO:004337490.041
Mouse
nucleoside phosphate catabolic processGO:19012922220.041
positive regulation of b cell activationGO:0050871490.041
regulation of chromatin modificationGO:1903308570.041
defense response to other organismGO:00985421970.041
regulation of cytoskeleton organizationGO:00514931220.041
positive regulation of mammary gland involutionGO:190352140.041
actin filament bundle assemblyGO:0051017400.041
positive regulation of myeloid cell differentiationGO:0045639430.041
g protein coupled receptor signaling pathwayGO:00071862430.041
gtp catabolic processGO:00061841430.041
nucleoside metabolic processGO:00091162460.041
protein modification by small protein conjugation or removalGO:00706472070.041
positive regulation of bindingGO:0051099490.040
Mouse
protein modification by small protein conjugationGO:00324461870.039
macromolecule catabolic processGO:00090572810.039
regulation of cellular component biogenesisGO:00440871810.039
development of primary male sexual characteristicsGO:0046546880.039
response to inorganic substanceGO:0010035960.039
mammary gland epithelium developmentGO:0061180650.039
Mouse
cellular response to external stimulusGO:0071496880.038
negative regulation of transferase activityGO:0051348850.038
cd4 positive alpha beta t cell differentiationGO:0043367410.038
Mouse
intracellular protein transportGO:00068862040.038
adherens junction organizationGO:0034332280.038
mammary gland duct morphogenesisGO:0060603380.038
microtubule cytoskeleton organizationGO:00002261570.038
carbohydrate derivative biosynthetic processGO:19011371830.038
cellular response to dna damage stimulusGO:00069742070.038
histone h3 acetylationGO:0043966140.038
Mouse
t helper cell lineage commitmentGO:000229560.038
Mouse
regulation of mitotic cell cycleGO:00073461260.038
mapk cascadeGO:00001652810.037
dendrite developmentGO:00163581150.037
response to type i interferonGO:0034340120.037
Mouse
development of primary sexual characteristicsGO:00451371430.037
cerebral cortex developmentGO:0021987860.037
neutrophil differentiationGO:003022330.037
mitotic cell cycleGO:00002781950.037
regulation of mapk cascadeGO:00434082480.037
g1 s transition of mitotic cell cycleGO:0000082570.036
regulation of homotypic cell cell adhesionGO:0034110130.036
cellular component assembly involved in morphogenesisGO:00109271390.036
antigen processing and presentation of exogenous peptide antigen via mhc class iiGO:0019886140.036
transmembrane transportGO:00550854120.036
regulation of alpha beta t cell activationGO:0046634530.036
Mouse
regulation of cell projection organizationGO:00313442060.036
positive regulation of response to cytokine stimulusGO:0060760110.036
Mouse
granulocyte chemotaxisGO:0071621390.036
purine ribonucleoside catabolic processGO:00461302050.036
spermatogenesisGO:00072832840.035
cd4 positive alpha beta t cell lineage commitmentGO:004337360.035
Mouse
regulation of neuron projection developmentGO:00109751690.035
positive regulation of gtpase activityGO:0043547850.035
carbohydrate homeostasisGO:00335001280.035
extracellular matrix organizationGO:00301981470.035
ovarian follicle developmentGO:0001541400.035
regulation of actin polymerization or depolymerizationGO:0008064450.035
positive regulation of cytokine biosynthetic processGO:0042108400.035
Mouse
positive regulation of alpha beta t cell activationGO:0046635390.035
morphogenesis of embryonic epitheliumGO:00163311590.035
histone modificationGO:00165701590.034
Mouse
protein catabolic processGO:00301632210.034
nephron developmentGO:00720061090.034
regulation of organ morphogenesisGO:20000271440.034
regulation of leukocyte mediated immunityGO:00027031040.034
positive regulation of behaviorGO:0048520400.034
regulation of myeloid leukocyte differentiationGO:0002761580.034
dendritic cell apoptotic processGO:009704830.034

Irf8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.396
disease of anatomical entityDOID:700.396
primary immunodeficiency diseaseDOID:61200.157
b cell deficiencyDOID:211500.040
hematopoietic system diseaseDOID:7400.037