IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Trap1

TNF receptor-associated protein 1

(Aliases: 2410002K23Rik,HSP75)

Ensembl: ENSMUSG00000005981
Entrez: 68015
UniProtKB: Q9CQN1

Process Predictions
Disease Predictions

Trap1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
nadh metabolic process	GO:0006734	1	0.511
coenzyme metabolic process	GO:0006732	52	0.444
citrate metabolic process	GO:0006101	3	0.166
oxidation reduction process	GO:0055114	342	0.119
nucleobase containing small molecule metabolic process	GO:0055086	352	0.109
mitochondrion organization	GO:0007005	134	0.100
generation of precursor metabolites and energy	GO:0006091	103	0.095
nucleoside monophosphate metabolic process	GO:0009123	85	0.091
organic cyclic compound catabolic process	GO:1901361	295	0.090
glycosyl compound metabolic process	GO:1901657	246	0.083
cellular nitrogen compound catabolic process	GO:0044270	280	0.082
cellular amino acid metabolic process	GO:0006520	103	0.081
protein processing	GO:0016485	163	0.074
purine containing compound metabolic process	GO:0072521	311	0.068
nucleoside phosphate metabolic process	GO:0006753	338	0.065
energy derivation by oxidation of organic compounds	GO:0015980	77	0.060
cellular respiration	GO:0045333	38	0.060
ribose phosphate metabolic process	GO:0019693	291	0.059
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.050
purine ribonucleotide metabolic process	GO:0009150	290	0.049
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.048
ribonucleotide metabolic process	GO:0009259	291	0.048
nucleoside metabolic process	GO:0009116	246	0.047
ribonucleoside metabolic process	GO:0009119	245	0.047
translation	GO:0006412	93	0.045
cellular ketone metabolic process	GO:0042180	84	0.044
protein maturation	GO:0051604	176	0.043
purine ribonucleoside metabolic process	GO:0046128	241	0.041
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.041
heterocycle catabolic process	GO:0046700	280	0.041
nucleotide metabolic process	GO:0009117	332	0.041
regulation of cellular amino acid metabolic process	GO:0006521	5	0.040
nad metabolic process	GO:0019674	7	0.039
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.038
nucleoside triphosphate metabolic process	GO:0009141	230	0.038
regulation of cellular ketone metabolic process	GO:0010565	66	0.037
tricarboxylic acid metabolic process	GO:0072350	5	0.036
dicarboxylic acid metabolic process	GO:0043648	18	0.034
purine nucleotide metabolic process	GO:0006163	302	0.033
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.033
atp metabolic process	GO:0046034	75	0.032
carboxylic acid biosynthetic process	GO:0046394	86	0.032
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.032
action potential	GO:0001508	78	0.031
organonitrogen compound biosynthetic process	GO:1901566	192	0.031
muscle fiber development	GO:0048747	76	0.031
cellular amine metabolic process	GO:0044106	44	0.031
positive regulation of interleukin 8 production	GO:0032757	2	0.031
alpha amino acid biosynthetic process	GO:1901607	15	0.030
purine nucleoside metabolic process	GO:0042278	241	0.029
nuclear transport	GO:0051169	139	0.029
aromatic compound catabolic process	GO:0019439	286	0.029
protein localization to organelle	GO:0033365	185	0.027
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.027
organonitrogen compound catabolic process	GO:1901565	264	0.027
ribonucleoside monophosphate catabolic process	GO:0009158	57	0.027
cellular lipid metabolic process	GO:0044255	323	0.027
regulation of cellular amine metabolic process	GO:0033238	20	0.026
posttranscriptional regulation of gene expression	GO:0010608	155	0.026
cofactor biosynthetic process	GO:0051188	41	0.026
transmembrane transport	GO:0055085	412	0.025
oxidoreduction coenzyme metabolic process	GO:0006733	16	0.025
cofactor metabolic process	GO:0051186	80	0.025
extrinsic apoptotic signaling pathway	GO:0097191	126	0.024
multicellular organismal signaling	GO:0035637	91	0.024
positive regulation of cellular amine metabolic process	GO:0033240	5	0.024
dna metabolic process	GO:0006259	303	0.023
trna wobble base modification	GO:0002097	2	0.023
intracellular protein transport	GO:0006886	204	0.023
iron sulfur cluster assembly	GO:0016226	3	0.022
organophosphate catabolic process	GO:0046434	232	0.022
mitochondrial protein processing	GO:0034982	5	0.021
hydrogen transport	GO:0006818	35	0.021
cytokine production	GO:0001816	319	0.021
amine metabolic process	GO:0009308	45	0.021
cation transport	GO:0006812	399	0.020
response to oxidative stress	GO:0006979	123	0.020	Rat Fly
cellular aldehyde metabolic process	GO:0006081	12	0.020
regulation of cytokine production	GO:0001817	266	0.019
monocarboxylic acid metabolic process	GO:0032787	191	0.019
carbohydrate derivative catabolic process	GO:1901136	231	0.019
macromolecule catabolic process	GO:0009057	281	0.019
renal system development	GO:0072001	225	0.019
transmission of nerve impulse	GO:0019226	76	0.019
ribonucleoside catabolic process	GO:0042454	206	0.019
cellular amino acid biosynthetic process	GO:0008652	22	0.018
carboxylic acid catabolic process	GO:0046395	51	0.018
nicotinamide nucleotide metabolic process	GO:0046496	12	0.018
defecation	GO:0030421	1	0.018
positive regulation of cell death	GO:0010942	224	0.018
intrinsic apoptotic signaling pathway	GO:0097193	132	0.018	Rat
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.018
germ cell development	GO:0007281	185	0.018
neuron apoptotic process	GO:0051402	142	0.018
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.017
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.017
regulation of lymphocyte activation	GO:0051249	240	0.017
cytoplasmic transport	GO:0016482	234	0.017
nucleoside phosphate catabolic process	GO:1901292	222	0.017
organic hydroxy compound metabolic process	GO:1901615	203	0.016
regulation of establishment of protein localization	GO:0070201	181	0.016
purine nucleoside monophosphate catabolic process	GO:0009128	58	0.016
nucleotide catabolic process	GO:0009166	217	0.016
skin development	GO:0043588	220	0.015
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.015	Rat
rna processing	GO:0006396	105	0.015
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.015
cellular modified amino acid metabolic process	GO:0006575	63	0.015
reactive oxygen species metabolic process	GO:0072593	84	0.015
locomotory behavior	GO:0007626	195	0.015
regulation of defense response	GO:0031347	233	0.015
microtubule cytoskeleton organization	GO:0000226	157	0.015
ensheathment of neurons	GO:0007272	76	0.014
reactive oxygen species biosynthetic process	GO:1903409	8	0.014
multicellular organismal homeostasis	GO:0048871	164	0.014
t cell activation	GO:0042110	289	0.014
purine nucleoside catabolic process	GO:0006152	205	0.014
positive regulation of protein phosphorylation	GO:0001934	242	0.014
nucleoside phosphate biosynthetic process	GO:1901293	79	0.014
nitrogen compound transport	GO:0071705	271	0.014
immune effector process	GO:0002252	321	0.014
spermatogenesis	GO:0007283	284	0.014
regulation of proteolysis	GO:0030162	164	0.014
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.014
neuron death	GO:0070997	154	0.014
cellular macromolecule catabolic process	GO:0044265	206	0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	62	0.013
carbohydrate derivative biosynthetic process	GO:1901137	183	0.013
regulation of cell activation	GO:0050865	289	0.013
aldehyde catabolic process	GO:0046185	4	0.013
urogenital system development	GO:0001655	261	0.013
neuronal action potential	GO:0019228	54	0.013
regulation of interleukin 8 production	GO:0032677	3	0.013
nucleoside monophosphate catabolic process	GO:0009125	59	0.013
regulation of organelle organization	GO:0033043	289	0.013
myeloid cell differentiation	GO:0030099	233	0.013
cellular response to cytokine stimulus	GO:0071345	189	0.013
cation transmembrane transport	GO:0098655	266	0.013
cellular protein complex assembly	GO:0043623	116	0.013
purine containing compound catabolic process	GO:0072523	213	0.013
cellular homeostasis	GO:0019725	240	0.013
regulation of neuron death	GO:1901214	134	0.013
microtubule based process	GO:0007017	236	0.013
epithelial cell development	GO:0002064	159	0.012
muscle tissue development	GO:0060537	308	0.012
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.012
regulation of protein localization	GO:0032880	231	0.012
ribonucleotide catabolic process	GO:0009261	208	0.012
regulation of membrane potential	GO:0042391	192	0.012
chemotaxis	GO:0006935	247	0.012
establishment of protein localization to organelle	GO:0072594	118	0.012
positive regulation of cytokine production	GO:0001819	174	0.012
gland development	GO:0048732	330	0.012
peptidyl amino acid modification	GO:0018193	336	0.012
cellular response to dna damage stimulus	GO:0006974	207	0.012
negative regulation of transferase activity	GO:0051348	85	0.012
negative regulation of organelle organization	GO:0010639	90	0.012
regulation of feeding behavior	GO:0060259	3	0.012
mitochondrial translation	GO:0032543	4	0.012
leukocyte differentiation	GO:0002521	342	0.012
leukocyte apoptotic process	GO:0071887	71	0.012
regulation of protein localization to nucleus	GO:1900180	60	0.012
homeostasis of number of cells	GO:0048872	210	0.011
regulation of protein transport	GO:0051223	163	0.011
pyridine nucleotide metabolic process	GO:0019362	12	0.011
negative regulation of cellular component organization	GO:0051129	194	0.011
negative regulation of protein phosphorylation	GO:0001933	126	0.011
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.011
positive regulation of cell development	GO:0010720	237	0.011
kidney development	GO:0001822	213	0.011
cellular response to oxidative stress	GO:0034599	76	0.011	Rat
myelination	GO:0042552	74	0.011
organic acid biosynthetic process	GO:0016053	86	0.011
response to organonitrogen compound	GO:0010243	246	0.011
regulation of intracellular transport	GO:0032386	159	0.011
regulation of ion transport	GO:0043269	215	0.011
cell type specific apoptotic process	GO:0097285	268	0.011
response to organic cyclic compound	GO:0014070	198	0.011
lymphocyte proliferation	GO:0046651	164	0.011
positive regulation of protein modification process	GO:0031401	299	0.011
regulation of inflammatory response	GO:0050727	147	0.011
muscle cell differentiation	GO:0042692	261	0.011
proton transport	GO:0015992	35	0.010
cellular modified amino acid biosynthetic process	GO:0042398	12	0.010
inorganic cation transmembrane transport	GO:0098662	207	0.010
sulfur compound metabolic process	GO:0006790	100	0.010
cation homeostasis	GO:0055080	212	0.010
ion transmembrane transport	GO:0034220	361	0.010
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway	GO:1902176	4	0.010	Rat
organic acid catabolic process	GO:0016054	51	0.010
nucleotide biosynthetic process	GO:0009165	78	0.010

Trap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.317
disease of anatomical entity	DOID:7	0.317
eye disease	DOID:5614	0.077
eye and adnexa disease	DOID:1492	0.077
sensory system disease	DOID:0050155	0.077
central nervous system disease	DOID:331	0.061
neurodegenerative disease	DOID:1289	0.045
retinal disease	DOID:5679	0.024
disease of metabolism	DOID:0014667	0.023
inherited metabolic disorder	DOID:655	0.023
retinitis pigmentosa	DOID:10584	0.019
retinal degeneration	DOID:8466	0.019

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