IMP: Integrative Multi-species Prediction

Mus musculus

120 known processes

Wnt2b

wingless related MMTV integration site 2b

(Aliases: Wnt13)

Entrez: 22414
Ensembl: ENSMUSG00000027840
UniProtKB: O70283

Process Predictions
Disease Predictions

Wnt2b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cardiac muscle tissue development	GO:0048738	130	0.784	Mouse
negative regulation of prostatic bud formation	GO:0060686	4	0.781	Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.725
ureteric bud development	GO:0001657	94	0.706
positive regulation of cell development	GO:0010720	237	0.693	Mouse
mesonephric tubule development	GO:0072164	94	0.693
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.640	Mouse
axon guidance	GO:0007411	141	0.629	Mouse
urogenital system development	GO:0001655	261	0.626
g protein coupled receptor signaling pathway	GO:0007186	243	0.574
regulation of purine nucleotide metabolic process	GO:1900542	169	0.559	Mouse
amine metabolic process	GO:0009308	45	0.541
somatotropin secreting cell differentiation	GO:0060126	4	0.534	Mouse
nephron epithelium morphogenesis	GO:0072088	68	0.525
embryonic organ morphogenesis	GO:0048562	276	0.520	Mouse
leukocyte differentiation	GO:0002521	342	0.517	Mouse
kidney development	GO:0001822	213	0.517
skeletal system morphogenesis	GO:0048705	203	0.502	Mouse
ureteric bud morphogenesis	GO:0060675	62	0.501
regulation of muscle tissue development	GO:1901861	97	0.494	Mouse
tube formation	GO:0035148	140	0.482	Mouse
paraxial mesodermal cell differentiation	GO:0048342	2	0.472	Mouse
renal tubule morphogenesis	GO:0061333	72	0.471
skeletal system development	GO:0001501	356	0.466	Human Mouse
axonogenesis	GO:0007409	274	0.463	Mouse
neuron projection guidance	GO:0097485	141	0.460	Mouse
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.454	Mouse
bmp signaling pathway	GO:0030509	93	0.450	Mouse
metanephros development	GO:0001656	79	0.448	Mouse
central nervous system neuron differentiation	GO:0021953	162	0.447	Mouse
nephron tubule morphogenesis	GO:0072078	68	0.445
muscle cell proliferation	GO:0033002	52	0.443	Mouse
polarity specification of proximal distal axis	GO:0010085	2	0.439	Mouse
angiogenesis	GO:0001525	201	0.430	Zebrafish Mouse
glandular epithelial cell differentiation	GO:0002067	38	0.422	Mouse
positive regulation of cell death	GO:0010942	224	0.418	Mouse
maintenance of cell number	GO:0098727	3	0.406	Mouse
muscle tissue development	GO:0060537	308	0.401	Mouse
cardiac muscle cell differentiation	GO:0055007	69	0.395	Mouse
spinal cord development	GO:0021510	81	0.395	Mouse
epithelial tube morphogenesis	GO:0060562	303	0.391
adult behavior	GO:0030534	135	0.390
stem cell proliferation	GO:0072089	117	0.383	Human Mouse
cellular homeostasis	GO:0019725	240	0.380
negative regulation of synapse assembly	GO:0051964	3	0.380	Mouse
extracellular structure organization	GO:0043062	148	0.380	Mouse
organic cyclic compound catabolic process	GO:1901361	295	0.372	Mouse
nephron development	GO:0072006	109	0.368
regulation of cardiac muscle cell proliferation	GO:0060043	23	0.368	Mouse
mesonephric epithelium development	GO:0072163	94	0.368
circulatory system process	GO:0003013	197	0.368
nephric duct formation	GO:0072179	4	0.367	Mouse
connective tissue development	GO:0061448	179	0.366	Human Mouse
developmental maturation	GO:0021700	193	0.366	Mouse
embryonic epithelial tube formation	GO:0001838	130	0.363	Mouse
cardiac chamber morphogenesis	GO:0003206	93	0.358	Mouse
renal tubule development	GO:0061326	87	0.357
striated muscle cell development	GO:0055002	125	0.354	Mouse
mesenchyme development	GO:0060485	152	0.351	Mouse
ossification	GO:0001503	216	0.347	Mouse
nucleobase containing small molecule metabolic process	GO:0055086	352	0.344	Mouse
positive regulation of branching involved in ureteric bud morphogenesis	GO:0090190	18	0.339
regulation of axon guidance	GO:1902667	13	0.336	Mouse
canonical wnt signaling pathway involved in regulation of cell proliferation	GO:0044340	3	0.336	Mouse
muscle cell differentiation	GO:0042692	261	0.336	Mouse
negative regulation of cell development	GO:0010721	169	0.334	Mouse
tertiary branching involved in mammary gland duct morphogenesis	GO:0060748	3	0.333	Mouse
mesonephric tubule morphogenesis	GO:0072171	63	0.332
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.331
regulation of secretion by cell	GO:1903530	249	0.330	Mouse
mesonephros development	GO:0001823	97	0.326
regulation of cardiac muscle tissue development	GO:0055024	31	0.325	Mouse
regulation of neuron differentiation	GO:0045664	281	0.322	Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.320
mesonephric duct formation	GO:0072181	2	0.316	Mouse
rho protein signal transduction	GO:0007266	32	0.314
rhythmic process	GO:0048511	174	0.312
cellular response to hormone stimulus	GO:0032870	150	0.311	Mouse
digestive system development	GO:0055123	200	0.311	Zebrafish Mouse
cellular amine metabolic process	GO:0044106	44	0.311
inner ear morphogenesis	GO:0042472	101	0.310	Mouse
chondrocyte differentiation	GO:0002062	72	0.306	Human Mouse
adenylate cyclase activating g protein coupled receptor signaling pathway	GO:0007189	30	0.304
t cell activation	GO:0042110	289	0.301	Mouse
paraxial mesodermal cell fate commitment	GO:0048343	2	0.301	Mouse
renal system development	GO:0072001	225	0.299
negative regulation of nervous system development	GO:0051961	156	0.298	Mouse
regulation of chondrocyte differentiation	GO:0032330	33	0.296	Mouse
nucleoside phosphate metabolic process	GO:0006753	338	0.290	Mouse
calcium ion homeostasis	GO:0055074	127	0.288
negative regulation of growth	GO:0045926	99	0.287	Mouse
purine containing compound metabolic process	GO:0072521	311	0.286	Mouse
morphogenesis of a branching structure	GO:0001763	203	0.278
female sex differentiation	GO:0046660	84	0.277	Mouse
organ induction	GO:0001759	21	0.276
regulation of secretion	GO:0051046	274	0.273	Mouse
central nervous system vasculogenesis	GO:0022009	3	0.270	Mouse
positive regulation of nervous system development	GO:0051962	221	0.270	Mouse
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.268	Mouse
phospholipase c activating g protein coupled receptor signaling pathway	GO:0007200	26	0.268
positive regulation of interleukin 8 secretion	GO:2000484	1	0.268	Mouse
myeloid cell differentiation	GO:0030099	233	0.268
regulation of mesonephros development	GO:0061217	24	0.264
regulation of cellular component biogenesis	GO:0044087	181	0.264	Mouse
midbrain hindbrain boundary maturation during brain development	GO:0022004	1	0.262	Mouse
mesoderm formation	GO:0001707	62	0.262	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	5	0.258
camp biosynthetic process	GO:0006171	31	0.257
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.255	Mouse
mesonephric tubule formation	GO:0072172	11	0.254	Mouse
positive regulation of cellular amine metabolic process	GO:0033240	5	0.253
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.253
respiratory system development	GO:0060541	190	0.252
neural tube development	GO:0021915	160	0.252	Mouse
establishment of organ orientation	GO:0048561	1	0.245	Mouse
regulation of kidney development	GO:0090183	40	0.245
regulation of testosterone biosynthetic process	GO:2000224	2	0.245	Mouse
purine nucleotide metabolic process	GO:0006163	302	0.244	Mouse
cytokine production	GO:0001816	319	0.244	Mouse
purine ribonucleotide metabolic process	GO:0009150	290	0.242	Mouse
striated muscle tissue development	GO:0014706	293	0.242	Mouse
regulation of blood circulation	GO:1903522	93	0.241
cyclic purine nucleotide metabolic process	GO:0052652	43	0.239
hormone secretion	GO:0046879	128	0.239
spemann organizer formation	GO:0060061	2	0.238	Mouse
hindbrain development	GO:0030902	128	0.236	Mouse
mapk cascade	GO:0000165	281	0.235	Mouse
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway	GO:0010579	3	0.234
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000079	1	0.232	Mouse
negative regulation of testosterone biosynthetic process	GO:2000225	1	0.227	Mouse
wnt signaling pathway calcium modulating pathway	GO:0007223	2	0.226	Mouse
stem cell maintenance	GO:0019827	130	0.226	Mouse
blood vessel morphogenesis	GO:0048514	285	0.225	Zebrafish Mouse
negative regulation of axon guidance	GO:1902668	8	0.224	Mouse
cell adhesion	GO:0007155	329	0.224	Mouse
regulation of cell activation	GO:0050865	289	0.224	Mouse
branching morphogenesis of an epithelial tube	GO:0048754	159	0.224
myoblast differentiation	GO:0045445	52	0.223	Mouse
locomotory behavior	GO:0007626	195	0.223
diencephalon development	GO:0021536	63	0.222	Mouse
negative regulation of cell proliferation	GO:0008285	296	0.221	Mouse
purine nucleotide biosynthetic process	GO:0006164	65	0.220
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	GO:0061350	2	0.219	Mouse
forebrain development	GO:0030900	302	0.219
regulation of cartilage development	GO:0061035	44	0.219	Mouse
telencephalon development	GO:0021537	186	0.219	Mouse
prostate gland development	GO:0030850	48	0.218	Mouse
lateral sprouting involved in mammary gland duct morphogenesis	GO:0060599	2	0.218	Mouse
cardiocyte differentiation	GO:0035051	87	0.216	Mouse
planar cell polarity pathway involved in ventricular septum morphogenesis	GO:0061348	2	0.214	Mouse
regulation of cell motility	GO:2000145	236	0.214	Mouse
t cell differentiation	GO:0030217	174	0.212	Mouse
lymphocyte differentiation	GO:0030098	242	0.210	Mouse
oxygen homeostasis	GO:0032364	2	0.208	Mouse
cellular carbohydrate metabolic process	GO:0044262	119	0.208
regulation of asymmetric cell division	GO:0009786	4	0.207	Mouse
endocrine system development	GO:0035270	98	0.207	Mouse
positive regulation of protein phosphorylation	GO:0001934	242	0.207	Mouse
trachea cartilage morphogenesis	GO:0060535	4	0.205	Mouse
regionalization	GO:0003002	337	0.205
forebrain neuron differentiation	GO:0021879	52	0.205	Mouse
hindlimb morphogenesis	GO:0035137	42	0.204	Mouse
endocrine pancreas development	GO:0031018	29	0.203	Mouse
determination of heart left right asymmetry	GO:0061371	48	0.202	Mouse
purine ribonucleotide biosynthetic process	GO:0009152	59	0.201
nephron epithelium development	GO:0072009	92	0.201
learning or memory	GO:0007611	148	0.200
cell differentiation in spinal cord	GO:0021515	53	0.200	Mouse
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000081	1	0.200	Mouse
regulation of body fluid levels	GO:0050878	162	0.199	Mouse
smoothened signaling pathway	GO:0007224	105	0.199	Mouse
renal outer medulla development	GO:0072054	2	0.198	Mouse
insulin secretion	GO:0030073	89	0.197
regulation of morphogenesis of a branching structure	GO:0060688	53	0.196
somatotropin secreting cell development	GO:0060133	2	0.196
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.196	Mouse
regulation of mesenchymal cell proliferation	GO:0010464	37	0.196	Mouse
somatic stem cell maintenance	GO:0035019	47	0.194	Mouse
lung development	GO:0030324	164	0.193
positive regulation of b cell proliferation	GO:0030890	24	0.193	Mouse
establishment of endothelial blood brain barrier	GO:0014045	3	0.193	Mouse
outflow tract morphogenesis	GO:0003151	53	0.192	Mouse
cellular ketone metabolic process	GO:0042180	84	0.191	Mouse
regulation of canonical wnt signaling pathway	GO:0060828	82	0.190	Human Mouse
regulation of cellular catabolic process	GO:0031329	242	0.186	Mouse
positive regulation of cyclic nucleotide biosynthetic process	GO:0030804	24	0.186
ribonucleotide biosynthetic process	GO:0009260	59	0.184
positive regulation of cell activation	GO:0050867	158	0.184	Mouse
ear morphogenesis	GO:0042471	118	0.183	Mouse
hindbrain formation	GO:0021576	1	0.182	Mouse
carbohydrate derivative biosynthetic process	GO:1901137	183	0.182
hypophysis morphogenesis	GO:0048850	3	0.181	Mouse
positive regulation of lymphocyte proliferation	GO:0050671	70	0.181	Mouse
embryonic skeletal system development	GO:0048706	120	0.180	Mouse
canonical wnt signaling pathway	GO:0060070	130	0.180
positive regulation of apoptotic process	GO:0043065	217	0.180	Mouse
cartilage development	GO:0051216	140	0.179	Human Mouse
neuron death	GO:0070997	154	0.178
positive regulation of protein modification process	GO:0031401	299	0.178	Mouse
regulation of striated muscle cell differentiation	GO:0051153	81	0.177
nephron morphogenesis	GO:0072028	69	0.176
ribose phosphate biosynthetic process	GO:0046390	59	0.175
nephron tubule development	GO:0072080	84	0.175
positive regulation of programmed cell death	GO:0043068	218	0.174	Mouse
epithelial cell proliferation	GO:0050673	174	0.173	Zebrafish Mouse
pituitary gland development	GO:0021983	38	0.173	Mouse
epithelial cell development	GO:0002064	159	0.171	Mouse
carbohydrate metabolic process	GO:0005975	230	0.171
regulation of epithelial cell migration	GO:0010632	35	0.171	Mouse
wnt signaling pathway involved in forebrain neuroblast division	GO:0021874	2	0.171	Mouse
central nervous system neuron development	GO:0021954	67	0.170	Mouse
ribonucleotide metabolic process	GO:0009259	291	0.170	Mouse
regulation of anagen	GO:0051884	1	0.170	Mouse
sensory organ morphogenesis	GO:0090596	242	0.170	Mouse
paraxial mesoderm morphogenesis	GO:0048340	10	0.169	Mouse
regulation of cell adhesion	GO:0030155	154	0.168	Mouse
metanephric nephron morphogenesis	GO:0072273	19	0.168	Mouse
cellular calcium ion homeostasis	GO:0006874	119	0.167
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.167	Mouse
cellular response to monosaccharide stimulus	GO:0071326	47	0.167
establishment of planar polarity involved in neural tube closure	GO:0090177	15	0.166	Mouse
myeloid leukocyte differentiation	GO:0002573	119	0.166
muscle contraction	GO:0006936	101	0.166
kidney epithelium development	GO:0072073	121	0.166
circadian rhythm	GO:0007623	114	0.165
male sex differentiation	GO:0046661	109	0.165	Human Mouse
positive regulation of nucleotide metabolic process	GO:0045981	114	0.164	Mouse
positive regulation of secretion by cell	GO:1903532	114	0.163	Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis	GO:0060501	3	0.161	Mouse
tube closure	GO:0060606	91	0.161	Mouse
negative regulation of androgen biosynthetic process	GO:2000180	1	0.160	Mouse
lung induction	GO:0060492	3	0.158
cell fate commitment	GO:0045165	210	0.158
regulation of gtp catabolic process	GO:0033124	113	0.157	Mouse
hematopoietic stem cell proliferation	GO:0071425	13	0.156	Human Mouse
peptide secretion	GO:0002790	114	0.156
forebrain neuron development	GO:0021884	30	0.155	Mouse
alcohol metabolic process	GO:0006066	116	0.154	Mouse
metanephric loop of henle development	GO:0072236	4	0.154	Mouse
extracellular matrix organization	GO:0030198	147	0.154	Mouse
development of primary sexual characteristics	GO:0045137	143	0.153	Human Mouse
positive regulation of cardiac muscle tissue growth	GO:0055023	15	0.152	Mouse
negative regulation of cell morphogenesis involved in differentiation	GO:0010771	48	0.152	Mouse
skeletal muscle organ development	GO:0060538	163	0.152	Mouse
transforming growth factor beta2 production	GO:0032906	2	0.152	Mouse
cerebellum formation	GO:0021588	1	0.151	Mouse
regulation of neural precursor cell proliferation	GO:2000177	70	0.151	Mouse
organ growth	GO:0035265	117	0.151	Mouse
cyclic nucleotide biosynthetic process	GO:0009190	44	0.151
cardiac chamber development	GO:0003205	108	0.151	Mouse
glucose homeostasis	GO:0042593	128	0.150
small gtpase mediated signal transduction	GO:0007264	97	0.150
regulation of angiogenesis	GO:0045765	81	0.149
mesenchymal cell differentiation	GO:0048762	107	0.149	Mouse
regulation of axon diameter	GO:0031133	6	0.149	Mouse
positive regulation of wnt signaling pathway	GO:0030177	45	0.148	Human Mouse
nucleotide biosynthetic process	GO:0009165	78	0.147
limb development	GO:0060173	166	0.147	Mouse
positive regulation of camp mediated signaling	GO:0043950	3	0.146
regulation of hormone secretion	GO:0046883	88	0.146
negative regulation of mesenchymal cell proliferation	GO:0072201	3	0.144	Mouse
spinal cord association neuron differentiation	GO:0021527	14	0.144	Mouse
regulation of neuron projection development	GO:0010975	169	0.143	Mouse
neural tube formation	GO:0001841	108	0.143	Mouse
coagulation	GO:0050817	78	0.142	Mouse
regulation of homeostatic process	GO:0032844	182	0.142
regulation of heart growth	GO:0060420	31	0.142	Mouse
positive regulation of transcription initiation from rna polymerase ii promoter	GO:0060261	5	0.140	Mouse
mesenchyme morphogenesis	GO:0072132	32	0.140	Mouse
digestive tract development	GO:0048565	190	0.140	Zebrafish Mouse
planar cell polarity pathway involved in pericardium morphogenesis	GO:0061354	2	0.140	Mouse
neuron projection extension involved in neuron projection guidance	GO:1902284	14	0.139	Mouse
metanephros morphogenesis	GO:0003338	24	0.139	Mouse
positive regulation of interleukin 8 production	GO:0032757	2	0.139	Mouse
mesenchymal cell development	GO:0014031	93	0.139	Mouse
negative regulation of neuron projection development	GO:0010977	50	0.139	Mouse
regulation of cellular amine metabolic process	GO:0033238	20	0.139
regulation of nucleotide biosynthetic process	GO:0030808	34	0.138
epithelial cell migration	GO:0010631	63	0.138	Mouse
guanosine containing compound metabolic process	GO:1901068	144	0.137	Mouse
neuroepithelial cell differentiation	GO:0060563	37	0.136	Mouse
negative regulation of wnt signaling pathway	GO:0030178	73	0.136	Mouse
regulation of lymphocyte proliferation	GO:0050670	117	0.136	Mouse
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.135	Mouse
cation homeostasis	GO:0055080	212	0.135
positive regulation of muscle tissue development	GO:1901863	32	0.134	Mouse
camp metabolic process	GO:0046058	40	0.134
establishment of anatomical structure orientation	GO:0048560	1	0.133	Mouse
b cell activation	GO:0042113	161	0.132	Mouse
negative regulation of neuron death	GO:1901215	98	0.131
heart morphogenesis	GO:0003007	178	0.130	Mouse
stem cell differentiation	GO:0048863	268	0.130	Mouse
respiratory tube development	GO:0030323	167	0.130
olfactory bulb development	GO:0021772	30	0.129	Mouse
neural tube patterning	GO:0021532	43	0.128	Mouse
positive regulation of neuron differentiation	GO:0045666	141	0.128	Mouse
regulation of cell projection organization	GO:0031344	206	0.128	Mouse
artery development	GO:0060840	53	0.128	Mouse
ribose phosphate metabolic process	GO:0019693	291	0.128	Mouse
positive regulation of mesenchymal cell proliferation	GO:0002053	33	0.128	Mouse
mesoderm morphogenesis	GO:0048332	64	0.127	Mouse
pallium development	GO:0021543	120	0.127	Mouse
cerebellum development	GO:0021549	77	0.126	Mouse
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.126	Mouse
stem cell development	GO:0048864	219	0.125	Mouse
single organism cell adhesion	GO:0098602	156	0.124	Mouse
kidney morphogenesis	GO:0060993	83	0.124
positive regulation of cardiac muscle tissue development	GO:0055025	19	0.124	Mouse
regulation of cell cycle	GO:0051726	281	0.124	Mouse
gliogenesis	GO:0042063	141	0.124
negative regulation of neuron differentiation	GO:0045665	101	0.123	Mouse
regulation of cyclic nucleotide metabolic process	GO:0030799	40	0.122
lung epithelium development	GO:0060428	37	0.122	Mouse
regulation of nucleotide metabolic process	GO:0006140	169	0.121	Mouse
carbohydrate homeostasis	GO:0033500	128	0.121
wound healing	GO:0042060	157	0.121	Zebrafish Mouse
neural precursor cell proliferation	GO:0061351	121	0.121	Mouse
cellular chemical homeostasis	GO:0055082	215	0.120
regulation of embryonic development	GO:0045995	71	0.119
divalent inorganic cation homeostasis	GO:0072507	138	0.119
positive regulation of kidney development	GO:0090184	28	0.119
regulation of bmp signaling pathway	GO:0030510	60	0.118	Mouse
bone mineralization	GO:0030282	54	0.118	Mouse
regulation of cytoskeleton organization	GO:0051493	122	0.118	Mouse
midbrain hindbrain boundary maturation	GO:0021732	1	0.117	Mouse
outer medullary collecting duct development	GO:0072060	1	0.117	Mouse
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.116	Mouse
kidney rudiment formation	GO:0072003	3	0.116	Mouse
muscle fiber development	GO:0048747	76	0.115	Mouse
lung field specification	GO:0060424	3	0.115
regulation of stem cell proliferation	GO:0072091	78	0.115	Mouse
regulation of neuron death	GO:1901214	134	0.114
regulation of heart contraction	GO:0008016	77	0.114
chemotaxis	GO:0006935	247	0.114	Mouse
positive regulation of mesonephros development	GO:0061213	20	0.114
ameboidal type cell migration	GO:0001667	128	0.113	Mouse
fibroblast growth factor production	GO:0090269	4	0.112	Mouse
regulation of anatomical structure size	GO:0090066	178	0.112	Mouse
leukocyte activation involved in immune response	GO:0002366	126	0.112
regulation of vasculature development	GO:1901342	88	0.111
forebrain generation of neurons	GO:0021872	63	0.111	Mouse
establishment or maintenance of polarity of embryonic epithelium	GO:0016332	1	0.110	Mouse
paramesonephric duct development	GO:0061205	3	0.110	Mouse
regulation of organ growth	GO:0046620	61	0.109	Mouse
cellular metal ion homeostasis	GO:0006875	151	0.109
axon extension involved in axon guidance	GO:0048846	14	0.109	Mouse
autonomic nervous system development	GO:0048483	43	0.109
dna templated transcriptional preinitiation complex assembly	GO:0070897	4	0.108	Mouse
establishment of planar polarity involved in nephron morphogenesis	GO:0072046	1	0.108	Mouse
somitogenesis	GO:0001756	69	0.108	Mouse
actin filament bundle assembly	GO:0051017	40	0.108	Mouse
neuroendocrine cell differentiation	GO:0061101	7	0.108	Mouse
muscle tissue morphogenesis	GO:0060415	53	0.108	Mouse
amide transport	GO:0042886	138	0.108
axis elongation involved in somitogenesis	GO:0090245	4	0.107	Mouse
biomineral tissue development	GO:0031214	64	0.106	Mouse
myotube differentiation	GO:0014902	105	0.106	Mouse
cell type specific apoptotic process	GO:0097285	268	0.105	Mouse
nucleotide metabolic process	GO:0009117	332	0.105	Mouse
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.105	Mouse
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation	GO:0044343	1	0.104	Mouse
purine containing compound biosynthetic process	GO:0072522	70	0.104
regulation of jnk cascade	GO:0046328	62	0.104	Mouse
leukocyte proliferation	GO:0070661	172	0.104	Mouse
ectoderm formation	GO:0001705	3	0.103
positive regulation of kinase activity	GO:0033674	155	0.103	Mouse
striated muscle cell proliferation	GO:0014855	39	0.102	Mouse
cognition	GO:0050890	149	0.102
anatomical structure regression	GO:0060033	9	0.102	Mouse
adenohypophysis development	GO:0021984	14	0.102	Mouse
organophosphate biosynthetic process	GO:0090407	122	0.102
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	GO:0014834	3	0.102	Mouse
regulation of interleukin 8 secretion	GO:2000482	2	0.101	Mouse
pancreatic pp cell fate commitment	GO:0003329	2	0.101
regulation of system process	GO:0044057	200	0.101
organic hydroxy compound biosynthetic process	GO:1901617	77	0.100	Mouse
peptide transport	GO:0015833	133	0.100
spermatogenesis	GO:0007283	284	0.100
uterus morphogenesis	GO:0061038	2	0.099	Mouse
limb morphogenesis	GO:0035108	149	0.099	Mouse
positive regulation of lymphocyte activation	GO:0051251	140	0.099	Mouse
dorsal spinal cord development	GO:0021516	20	0.098	Mouse
epithelial tube formation	GO:0072175	130	0.098	Mouse
cop9 signalosome assembly	GO:0010387	2	0.098	Mouse
regulation of wound healing	GO:0061041	40	0.098	Mouse
positive regulation of cartilage development	GO:0061036	18	0.097	Mouse
regulation of cardiac muscle tissue growth	GO:0055021	26	0.096	Mouse
negative regulation of cell growth	GO:0030308	44	0.096	Mouse
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.096
regulation of muscle system process	GO:0090257	80	0.096
regulation of branching involved in ureteric bud morphogenesis	GO:0090189	22	0.095
blood circulation	GO:0008015	195	0.095
planar cell polarity pathway involved in cardiac right atrium morphogenesis	GO:0061349	2	0.095	Mouse
gland development	GO:0048732	330	0.094	Zebrafish Mouse
regulation of insulin secretion involved in cellular response to glucose stimulus	GO:0061178	31	0.094
cardiac muscle cell proliferation	GO:0060038	31	0.094	Mouse
segmentation	GO:0035282	93	0.093	Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.093	Mouse
spemann organizer formation at the anterior end of the primitive streak	GO:0060064	1	0.093	Mouse
apoptotic process involved in morphogenesis	GO:0060561	25	0.093	Mouse
oxidation reduction process	GO:0055114	342	0.093
mammary gland epithelium development	GO:0061180	65	0.092	Mouse
regulation of organ morphogenesis	GO:2000027	144	0.092
regulation of myeloid cell differentiation	GO:0045637	96	0.092
odontogenesis	GO:0042476	78	0.092	Mouse
regulation of cell migration	GO:0030334	219	0.092	Mouse
purine ribonucleoside metabolic process	GO:0046128	241	0.091	Mouse
male genitalia development	GO:0030539	20	0.091	Mouse
response to nutrient levels	GO:0031667	109	0.091
regulation of carbohydrate metabolic process	GO:0006109	75	0.091
lung morphogenesis	GO:0060425	50	0.090
cellular response to organic cyclic compound	GO:0071407	87	0.090	Mouse
regulation of camp metabolic process	GO:0030814	30	0.090
regulation of peptide secretion	GO:0002791	77	0.089
regulation of stress fiber assembly	GO:0051492	15	0.089	Mouse
peptide hormone secretion	GO:0030072	109	0.087
cellular response to glucose stimulus	GO:0071333	45	0.087
ion transmembrane transport	GO:0034220	361	0.087
heart contraction	GO:0060047	93	0.087
positive regulation of anagen	GO:0051885	1	0.086	Mouse
purine containing compound catabolic process	GO:0072523	213	0.086	Mouse
regulation of tube size	GO:0035150	57	0.086	Mouse
cardiac muscle tissue growth	GO:0055017	37	0.086	Mouse
hindbrain morphogenesis	GO:0021575	46	0.086	Mouse
atrial cardiac muscle tissue development	GO:0003228	5	0.086	Mouse
somite development	GO:0061053	81	0.085	Mouse
metal ion homeostasis	GO:0055065	189	0.085
regulation of stem cell differentiation	GO:2000736	50	0.085
morphogenesis of embryonic epithelium	GO:0016331	159	0.085
placenta development	GO:0001890	140	0.084	Mouse
renal inner medulla development	GO:0072053	3	0.084	Mouse
body morphogenesis	GO:0010171	45	0.084	Mouse
bone development	GO:0060348	120	0.084
hippocampus development	GO:0021766	52	0.084	Mouse
regulation of apoptotic signaling pathway	GO:2001233	197	0.083	Mouse
response to organonitrogen compound	GO:0010243	246	0.083	Mouse
labyrinthine layer blood vessel development	GO:0060716	21	0.083	Mouse
gastrulation	GO:0007369	116	0.083	Mouse
neural fold elevation formation	GO:0021502	1	0.083
type b pancreatic cell differentiation	GO:0003309	13	0.083	Mouse
regulation of gliogenesis	GO:0014013	50	0.083
metanephric nephron development	GO:0072210	34	0.083	Mouse
male gamete generation	GO:0048232	285	0.083
type b pancreatic cell proliferation	GO:0044342	10	0.082
skeletal muscle cell differentiation	GO:0035914	66	0.082	Mouse
positive regulation of camp biosynthetic process	GO:0030819	19	0.082
digestive tract morphogenesis	GO:0048546	147	0.082	Zebrafish Mouse
positive regulation of cell cycle	GO:0045787	92	0.082	Mouse
developmental induction	GO:0031128	34	0.081
regulation of response to wounding	GO:1903034	189	0.081	Mouse
sensory perception of chemical stimulus	GO:0007606	51	0.081	Mouse
lung epithelial cell differentiation	GO:0060487	29	0.081
regulation of hormone levels	GO:0010817	211	0.080	Mouse
positive regulation of meiosis	GO:0045836	14	0.080	Mouse
ribonucleoside catabolic process	GO:0042454	206	0.080	Mouse
cellular response to carbohydrate stimulus	GO:0071322	50	0.080
regulation of actin filament bundle assembly	GO:0032231	18	0.079	Mouse
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.079	Mouse
positive regulation of heart growth	GO:0060421	18	0.078	Mouse
germ cell development	GO:0007281	185	0.078	Mouse
negative regulation of bmp signaling pathway	GO:0030514	35	0.078	Mouse
cerebellum morphogenesis	GO:0021587	42	0.078	Mouse
endochondral bone morphogenesis	GO:0060350	50	0.078
positive regulation of the force of heart contraction by chemical signal	GO:0003099	3	0.077
bone morphogenesis	GO:0060349	78	0.077
non canonical wnt signaling pathway involved in heart development	GO:0061341	3	0.077	Mouse
muscle cell development	GO:0055001	133	0.077	Mouse
general adaptation syndrome	GO:0051866	2	0.077
regulation of binding	GO:0051098	111	0.077
actomyosin structure organization	GO:0031032	56	0.077	Mouse
positive regulation of b cell activation	GO:0050871	49	0.077	Mouse
t cell proliferation	GO:0042098	120	0.076	Mouse
immune effector process	GO:0002252	321	0.076
cardiac ventricle development	GO:0003231	83	0.076	Mouse
cell maturation	GO:0048469	127	0.075
gonad development	GO:0008406	141	0.075	Human Mouse
positive regulation of striated muscle tissue development	GO:0045844	31	0.075	Mouse
mesoderm development	GO:0007498	100	0.074	Mouse
regulation of actin cytoskeleton organization	GO:0032956	84	0.074	Mouse
camera type eye development	GO:0043010	266	0.074
specification of organ identity	GO:0010092	30	0.074
energy derivation by oxidation of organic compounds	GO:0015980	77	0.074
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.073	Mouse
mitral valve development	GO:0003174	4	0.073
cyclic nucleotide metabolic process	GO:0009187	59	0.073
neuron apoptotic process	GO:0051402	142	0.073
nitrogen compound transport	GO:0071705	271	0.073
metencephalon development	GO:0022037	89	0.072	Mouse
regulation of synapse assembly	GO:0051963	29	0.072	Mouse
regulation of camp biosynthetic process	GO:0030817	25	0.072
renal vesicle induction	GO:0072034	3	0.072	Mouse
embryonic placenta development	GO:0001892	98	0.072	Mouse
metanephric epithelium development	GO:0072207	21	0.072	Mouse
b cell activation involved in immune response	GO:0002312	50	0.072
aromatic compound catabolic process	GO:0019439	286	0.071	Mouse
ubiquitin dependent smad protein catabolic process	GO:0030579	2	0.071	Mouse
embryonic heart tube development	GO:0035050	65	0.071	Mouse

Wnt2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.143
	musculoskeletal system disease	DOID:17	0	0.143

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