Mus musculus

0 known processes

Ctla4

cytotoxic T-lymphocyte-associated protein 4

(Aliases: Cd152,Ly-56,Ctla-4)

Ctla4 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of defense responseGO:00313472330.814
Mouse
immune response activating cell surface receptor signaling pathwayGO:0002429720.743
Human Mouse
immune effector processGO:00022523210.694
Mouse
lymphocyte mediated immunityGO:00024491390.638
Mouse
regulation of interleukin 2 productionGO:0032663280.636
Mouse
interleukin 2 productionGO:0032623330.587
Mouse
regulation of cell activationGO:00508652890.563
Human Mouse
t cell differentiationGO:00302171740.557
Human Mouse
cytokine productionGO:00018163190.526
Mouse
negative regulation of immune system processGO:00026832090.496
Human
cellular response to cytokine stimulusGO:00713451890.496
interleukin 12 secretionGO:007261030.478
positive regulation of cytokine productionGO:00018191740.476
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.471
Mouse
leukocyte proliferationGO:00706611720.443
Human Mouse
regulation of monocyte chemotaxisGO:009002530.424
regulation of leukocyte proliferationGO:00706631210.410
Human Mouse
leukocyte differentiationGO:00025213420.410
Human Mouse
lymphocyte differentiationGO:00300982420.400
Human Mouse
regulation of cytokine productionGO:00018172660.382
Mouse
positive regulation of defense responseGO:00313491240.375
Mouse
positive regulation of t cell activationGO:00508701010.373
Mouse
t cell activationGO:00421102890.361
Human Mouse
immune response activating signal transductionGO:00027571160.349
Human Mouse
regulation of t cell activationGO:00508631700.343
Human Mouse
adaptive immune responseGO:00022501550.338
Mouse
leukocyte mediated immunityGO:00024431740.328
Mouse
regulation of protein transportGO:00512231630.323
positive regulation of lymphocyte proliferationGO:0050671700.320
Mouse
cytokine secretionGO:0050663720.318
cellular amino acid metabolic processGO:00065201030.316
positive regulation of t cell proliferationGO:0042102520.315
Mouse
inflammatory responseGO:00069542440.314
Mouse
regulation of lymphocyte mediated immunityGO:0002706840.309
Mouse
regulation of t cell anergyGO:000266740.298
regulation of cellular amine metabolic processGO:0033238200.287
antigen receptor mediated signaling pathwayGO:0050851640.283
Human Mouse
positive regulation of leukocyte proliferationGO:0070665730.275
Mouse
regulation of alpha beta t cell activationGO:0046634530.275
Mouse
activation of immune responseGO:00022531380.262
Human Mouse
regulation of secretion by cellGO:19035302490.261
positive regulation of lymphocyte activationGO:00512511400.256
Mouse
t cell proliferationGO:00420981200.248
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.245
Mouse
regulation of lymphocyte proliferationGO:00506701170.244
Human Mouse
mature dendritic cell differentiationGO:009702930.242
positive regulation of t cell costimulationGO:200052520.237
response to molecule of bacterial originGO:00022371430.235
alpha beta t cell proliferationGO:0046633210.233
Mouse
t cell differentiation in thymusGO:0033077770.227
Mouse
defense response to other organismGO:00985421970.226
positive regulation of cellular amine metabolic processGO:003324050.225
gliogenesisGO:00420631410.221
t cell anergyGO:000287040.220
granzyme mediated apoptotic signaling pathwayGO:000862610.217
regulation of innate immune responseGO:0045088910.215
cd8 positive alpha beta t cell extravasationGO:003569730.213
regulation of interferon gamma productionGO:0032649570.210
regulation of cytokine biosynthetic processGO:0042035590.207
Mouse
regulation of inflammatory responseGO:00507271470.207
Mouse
negative regulation of protein metabolic processGO:00512482820.204
alpha beta t cell activationGO:0046631910.203
Mouse
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.200
positive regulation of immune effector processGO:00026991070.197
Mouse
positive regulation of cell activationGO:00508671580.195
Mouse
regulation of lymphocyte anergyGO:000291140.195
regulation of protein localizationGO:00328802310.193
cell type specific apoptotic processGO:00972852680.192
eosinophil mediated immunityGO:000244710.191
immunoglobulin productionGO:0002377730.189
Mouse
regulation of alpha beta t cell proliferationGO:0046640180.184
Mouse
t cell costimulationGO:0031295140.180
Mouse
myeloid cell differentiationGO:00300992330.179
positive regulation of innate immune responseGO:0045089800.178
protein processingGO:00164851630.178
amine metabolic processGO:0009308450.172
lymphocyte proliferationGO:00466511640.170
Human Mouse
protein secretionGO:00093061110.168
response to lipopolysaccharideGO:00324961280.167
positive regulation of alpha beta t cell activationGO:0046635390.166
Mouse
immune response regulating cell surface receptor signaling pathwayGO:0002768800.164
Human Mouse
leukocyte activation involved in immune responseGO:00023661260.161
Mouse
positive regulation of cell deathGO:00109422240.159
Human
regulation of b cell mediated immunityGO:0002712370.158
Mouse
dna recombinationGO:0006310920.154
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.153
positive regulation of monocyte chemotaxisGO:009002620.153
regulation of leukocyte mediated immunityGO:00027031040.152
Mouse
chemotaxisGO:00069352470.151
negative regulation of macrophage apoptotic processGO:200011030.146
regulation of lymphocyte activationGO:00512492400.146
Human Mouse
immune response regulating signaling pathwayGO:00027641250.146
Human Mouse
positive regulation of programmed cell deathGO:00430682180.145
Human
positive regulation of inflammatory responseGO:0050729470.145
Mouse
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.144
regulation of establishment of protein localizationGO:00702011810.143
apoptotic signaling pathwayGO:00971903060.141
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.140
b cell activationGO:00421131610.139
Human Mouse
positive regulation of protein transportGO:0051222930.139
cellular ketone metabolic processGO:0042180840.138
protein maturationGO:00516041760.138
regulation of lymphocyte differentiationGO:00456191070.138
Human
negative regulation of hydrolase activityGO:0051346710.138
sequestering of calcium ionGO:0051208180.137
negative thymic t cell selectionGO:0045060120.135
Mouse
negative regulation of interleukin 2 biosynthetic processGO:004508530.133
regulation of cytokine secretionGO:0050707610.130
g protein coupled receptor signaling pathwayGO:00071862430.130
regulation of vesicle mediated transportGO:00606271390.128
immunoglobulin mediated immune responseGO:0016064690.126
Mouse
regulation of cellular ketone metabolic processGO:0010565660.125
interleukin 2 biosynthetic processGO:0042094150.125
Mouse
regulation of cellular amino acid metabolic processGO:000652150.123
negative regulation of cell activationGO:00508661110.122
Human
cellular response to lipopolysaccharideGO:0071222770.118
natural killer cell activationGO:0030101440.118
cation transportGO:00068123990.117
eosinophil activation involved in immune responseGO:000227810.116
regulation of immunoglobulin productionGO:0002637420.115
Mouse
lymphocyte costimulationGO:0031294150.115
Mouse
positive regulation of t cell anergyGO:000266940.114
somatic recombination of immunoglobulin gene segmentsGO:0016447420.112
Mouse
positive regulation of apoptotic processGO:00430652170.112
Human
interferon gamma productionGO:0032609670.112
regulation of t cell costimulationGO:200052320.110
morphogenesis of a branching epitheliumGO:00611381930.109
interleukin 1 beta secretionGO:0050702160.109
negative regulation of defense responseGO:0031348770.109
glycoprotein biosynthetic processGO:0009101890.108
divalent metal ion transportGO:00708381720.106
innate immune responseGO:00450871570.106
myeloid leukocyte differentiationGO:00025731190.105
positive regulation of alpha beta t cell differentiationGO:0046638280.103
regulation of chemotaxisGO:0050920530.102
regulation of kinase activityGO:00435492490.102
negative regulation of t cell activationGO:0050868650.102
Human
production of molecular mediator of immune responseGO:00024401030.100
Mouse
positive regulation of cell killingGO:0031343330.100
regulation of t cell extravasationGO:200040730.100
helper t cell chemotaxisGO:003570410.099
regulation of cell killingGO:0031341400.098
regulation of interleukin 2 biosynthetic processGO:0045076130.098
Mouse
negative regulation of leukocyte mediated immunityGO:0002704290.098
branching morphogenesis of an epithelial tubeGO:00487541590.098
natural killer cell inhibitory signaling pathwayGO:000276920.098
negative regulation of secretion by cellGO:1903531540.097
regulation of angiogenesisGO:0045765810.097
cellular amine metabolic processGO:0044106440.095
positive regulation of interferon gamma productionGO:0032729390.095
sequestering of metal ionGO:0051238190.095
cell killingGO:0001906670.094
immune complex clearanceGO:000243420.094
regulation of dendritic cell chemotaxisGO:200050810.093
regulation of adaptive immune responseGO:0002819900.093
Mouse
epithelial tube morphogenesisGO:00605623030.093
calcium ion transportGO:00068161590.093
regulation of antigen receptor mediated signaling pathwayGO:0050854290.092
eosinophil activationGO:004330710.092
striated muscle tissue developmentGO:00147062930.091
regulation of eosinophil migrationGO:200041620.090
regulation of membrane potentialGO:00423911920.089
cdc42 protein signal transductionGO:003248800.089
peptidyl tyrosine modificationGO:00182121450.089
cellular response to interleukin 15GO:007135020.088
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.088
regulation of intracellular transportGO:00323861590.088
regulation of protein secretionGO:0050708820.086
regulation of secretionGO:00510462740.085
cytokine biosynthetic processGO:0042089680.085
Mouse
positive regulation of protein phosphorylationGO:00019342420.085
regulation of hydrolase activityGO:00513362460.085
positive regulation of alpha beta t cell proliferationGO:0046641120.085
Mouse
regulation of muscle tissue developmentGO:1901861970.084
negative regulation of cellular amino acid metabolic processGO:004576300.083
purine nucleoside metabolic processGO:00422782410.082
leukocyte mediated cytotoxicityGO:0001909620.082
positive regulation of lymphocyte anergyGO:000291340.082
regulation of leukocyte differentiationGO:19021051590.081
Human
negative regulation of immune effector processGO:0002698550.081
cytokine mediated signaling pathwayGO:00192211150.079
negative regulation of cellular amine metabolic processGO:003323910.079
regulation of epithelial cell proliferationGO:00506781410.078
positive regulation of t helper 1 cell differentiationGO:004562740.078
t cell receptor signaling pathwayGO:0050852460.078
Mouse
regulation of protein kinase activityGO:00458592320.077
muscle tissue developmentGO:00605373080.077
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.077
peptidyl tyrosine phosphorylationGO:00181081430.076
regulation of t cell proliferationGO:0042129920.076
Mouse
negative regulation of secretionGO:0051048610.076
lymphocyte anergyGO:000224940.076
negative regulation of cell proliferationGO:00082852960.075
Human
regulation of leukocyte mediated cytotoxicityGO:0001910380.074
negative regulation of interleukin 2 productionGO:003270380.073
second messenger mediated signalingGO:0019932730.073
myeloid cell apoptotic processGO:0033028220.073
negative regulation of eosinophil degranulationGO:004331010.072
leukocyte apoptotic processGO:0071887710.071
regulation of inflammatory response to antigenic stimulusGO:0002861210.071
Mouse
regulation of protein maturationGO:1903317960.071
positive regulation of epithelial cell proliferationGO:0050679680.070
regulation of b cell activationGO:0050864810.070
Human Mouse
cd4 positive alpha beta t cell differentiationGO:0043367410.069
maintenance of locationGO:0051235890.069
cellular response to biotic stimulusGO:0071216920.069
regulation of ion homeostasisGO:2000021640.068
positive regulation of t cell receptor signaling pathwayGO:005086240.068
regulation of vasculature developmentGO:1901342880.068
positive regulation of natural killer cell mediated cytotoxicityGO:0045954160.067
interleukin 2 mediated signaling pathwayGO:003811020.067
negative regulation of molecular functionGO:00440922580.067
cytoplasmic transportGO:00164822340.067
b cell chemotaxisGO:003575430.066
positive regulation of leukocyte mediated immunityGO:0002705700.066
Mouse
mitotic cell cycle processGO:19030471590.066
stimulatory c type lectin receptor signaling pathwayGO:000222320.066
actin cytoskeleton organizationGO:00300362200.065
hematopoietic stem cell migrationGO:003570110.065
cellular response to hormone stimulusGO:00328701500.065
microglial cell activation involved in immune responseGO:000228210.064
regulation of immunoglobulin mediated immune responseGO:0002889370.063
Mouse
t helper 1 type immune responseGO:0042088250.063
stem cell developmentGO:00488642190.062
regulation of response to woundingGO:19030341890.062
Mouse
neuron deathGO:00709971540.061
camera type eye developmentGO:00430102660.061
regulation of proteolysisGO:00301621640.061
cell fate commitmentGO:00451652100.061
peptidyl amino acid modificationGO:00181933360.061
endomembrane system organizationGO:00102561470.061
negative regulation of cellular component organizationGO:00511291940.060
multicellular organismal signalingGO:0035637910.060
interleukin 10 secretionGO:007260840.059
positive regulation of b cell mediated immunityGO:0002714260.059
Mouse
endocytosisGO:00068971680.059
regulation of peptidase activityGO:0052547960.058
positive regulation of interleukin 2 biosynthetic processGO:004508680.058
Mouse
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.057
positive regulation of t cell extravasationGO:200040920.057
extrinsic apoptotic signaling pathwayGO:00971911260.057
regulation of cell projection organizationGO:00313442060.056
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.056
Mouse
positive regulation of dendritic cell chemotaxisGO:200051010.056
positive regulation of protein modification processGO:00314012990.056
positive regulation of lymphocyte mediated immunityGO:0002708620.056
Mouse
positive regulation of lymphocyte differentiationGO:0045621610.056
t cell selectionGO:0045058340.056
Mouse
t helper cell differentiationGO:0042093280.055
negative t cell selectionGO:0043383130.055
Mouse
epithelial cell proliferationGO:00506731740.055
regulation of monocyte extravasationGO:200043720.055
cellular response to lipidGO:00713961450.055
cell activation involved in immune responseGO:00022631260.055
Mouse
eosinophil degranulationGO:004330810.055
t cell differentiation involved in immune responseGO:0002292300.055
regulation of immunological synapse formationGO:200052020.054
positive regulation of thymocyte migrationGO:200041220.054
divalent inorganic cation homeostasisGO:00725071380.054
regulation of transferase activityGO:00513382630.054
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.054
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formationGO:200052610.053
dendritic cell chemotaxisGO:000240770.053
positive regulation of immunological synapse formationGO:200052210.053
cell chemotaxisGO:0060326810.053
positive regulation of protein kinase b signalingGO:0051897320.053
Mouse
cytokine metabolic processGO:0042107710.052
Mouse
inflammatory response to antigenic stimulusGO:0002437300.052
Mouse
positive regulation of cd4 positive alpha beta t cell proliferationGO:200056310.052
negative regulation of growthGO:0045926990.052
positive regulation of protein kinase activityGO:00458601440.052
regulation of hypersensitivityGO:0002883100.052
skeletal muscle organ developmentGO:00605381630.051
protein kinase b signalingGO:0043491740.051
Mouse
ensheathment of neuronsGO:0007272760.051
positive regulation of hydrolase activityGO:00513451480.051
t helper 17 cell chemotaxisGO:003570510.050
regulation of angiotensin levels in bloodGO:000200240.050
b cell mediated immunityGO:0019724710.050
Mouse
response to growth factorGO:00708481980.050
positive regulation of monocyte extravasationGO:200043910.050
alpha beta t cell activation involved in immune responseGO:0002287310.049
negative regulation of homeostatic processGO:0032845710.049
eosinophil migrationGO:007267730.049
positive regulation of cytokine secretionGO:0050715410.049
regulation of t cell mediated immunityGO:0002709340.049
stem cell differentiationGO:00488632680.049
metal ion homeostasisGO:00550651890.048
neuron migrationGO:00017641220.048
blood vessel morphogenesisGO:00485142850.048
myeloid leukocyte mediated immunityGO:0002444420.048
angiogenesisGO:00015252010.047
cellular response to organonitrogen compoundGO:00714171450.047
myeloid leukocyte activationGO:0002274830.047
positive regulation of hematopoietic stem cell migrationGO:200047310.047
axon ensheathmentGO:0008366760.047
skin developmentGO:00435882200.047
cellular response to dna damage stimulusGO:00069742070.047
Human
negative regulation of multi organism processGO:0043901680.046
regulation of b cell proliferationGO:0030888390.046
Human
t helper 2 cell cytokine productionGO:003574540.046
urogenital system developmentGO:00016552610.046
interleukin 8 secretionGO:007260630.046
axonogenesisGO:00074092740.046
regulation of apoptotic signaling pathwayGO:20012331970.046
carbohydrate metabolic processGO:00059752300.046
gland developmentGO:00487323300.046
positive regulation of protein secretionGO:0050714520.046
negative regulation of apoptotic signaling pathwayGO:20012341040.045
membrane organizationGO:00610242450.045
regulation of eosinophil degranulationGO:004330910.045
homeostasis of number of cellsGO:00488722100.045
t cell mediated immunityGO:0002456500.045
neuronal action potentialGO:0019228540.044
cellular response to growth factor stimulusGO:00713631970.044
ameboidal type cell migrationGO:00016671280.044
organic cyclic compound catabolic processGO:19013612950.044
purine ribonucleoside metabolic processGO:00461282410.044
regulation of organelle organizationGO:00330432890.044
interleukin 1 secretionGO:0050701160.044
positive regulation of leukocyte differentiationGO:1902107860.044
regulation of angiotensin metabolic processGO:006017740.043
glycoprotein metabolic processGO:00091001160.043
forebrain developmentGO:00309003020.043
negative regulation of lymphocyte activationGO:0051250910.043
Human
negative regulation of leukocyte proliferationGO:0070664460.043
Human
inflammatory cell apoptotic processGO:0006925110.043
organonitrogen compound catabolic processGO:19015652640.042
regulation of production of molecular mediator of immune responseGO:0002700650.042
Mouse
response to acid chemicalGO:00011011110.042
t helper 1 cell cytokine productionGO:003574410.040
negative regulation of proteolysisGO:0045861740.040
response to interferon gammaGO:0034341340.040
regulation of interleukin 4 biosynthetic processGO:004540230.040
positive regulation of angiogenesisGO:0045766460.040
plasma membrane organizationGO:0007009900.040
natural killer cell mediated immunityGO:0002228290.040
regulation of neuron apoptotic processGO:00435231220.040
positive regulation of t cell differentiationGO:0045582520.040
regulation of cysteine type endopeptidase activityGO:2000116650.039
dna metabolic processGO:00062593030.039
Mouse
neutrophil mediated killing of gram positive bacteriumGO:007094620.039
tumor necrosis factor productionGO:0032640500.039
positive regulation of muscle cell differentiationGO:0051149390.039
fertilizationGO:00095661270.038
positive regulation of b cell chemotaxisGO:200053820.038
neuron apoptotic processGO:00514021420.038
myeloid leukocyte migrationGO:0097529570.038
negative regulation of protein processingGO:0010955790.038
regulation of t helper 1 type immune responseGO:0002825170.038
regulation of homeostatic processGO:00328441820.038
positive regulation of response to woundingGO:1903036660.037
Mouse
somatic cell dna recombinationGO:0016444510.037
Mouse
regulation of cd4 positive alpha beta t cell activationGO:2000514240.037
negative regulation of intracellular signal transductionGO:19025321670.037
t helper 1 cell differentiationGO:0045063130.037
sensory perceptionGO:00076002450.037
purine nucleoside triphosphate catabolic processGO:00091462030.037
positive regulation of immunoglobulin production in mucosal tissueGO:200055810.036
response to interleukin 4GO:0070670230.036
positive regulation of mapk cascadeGO:00434101700.036
regulation of t helper 2 cell cytokine productionGO:200055130.036
mitotic cell cycleGO:00002781950.036
positive regulation of tumor necrosis factor productionGO:0032760300.036
rho protein signal transductionGO:0007266320.036
nucleocytoplasmic transportGO:00069131390.036
negative regulation of vasculature developmentGO:1901343260.035
interleukin 4 productionGO:0032633240.035
humoral immune responseGO:0006959570.035
monocyte chemotaxisGO:000254850.035
positive regulation of eosinophil migrationGO:200041820.035
stress activated protein kinase signaling cascadeGO:0031098810.035
protein localization to nucleusGO:00345041210.034
type 2 immune responseGO:0042092230.034
cellular metal ion homeostasisGO:00068751510.034
myoblast differentiationGO:0045445520.034
antibacterial peptide productionGO:000277820.034
nucleoside phosphate metabolic processGO:00067533380.034
telencephalon developmentGO:00215371860.034
cellular homeostasisGO:00197252400.034
positive regulation of nucleotide metabolic processGO:00459811140.034
small gtpase mediated signal transductionGO:0007264970.034
regulation of cellular response to stressGO:00801351590.034
regulation of cell cycleGO:00517262810.034
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.034
Mouse
positive regulation of cell projection organizationGO:0031346950.034
developmental growth involved in morphogenesisGO:00605601380.033
myotube differentiationGO:00149021050.033
skeletal muscle fiber developmentGO:0048741580.033
defense response to bacteriumGO:00427421190.033
monocyte extravasationGO:003569620.033
positive regulation of striated muscle cell differentiationGO:0051155350.033
defense response to gram positive bacteriumGO:0050830500.033
action potentialGO:0001508780.033
regulation of cellular component biogenesisGO:00440871810.033
positive regulation of behaviorGO:0048520400.033
nuclear transportGO:00511691390.033
regulation of regulated secretory pathwayGO:1903305200.033
regulation of neuron deathGO:19012141340.033
cell recognitionGO:0008037830.032
lymphocyte activation involved in immune responseGO:0002285930.032
Mouse
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.032
Mouse
regulation of cd4 positive alpha beta t cell proliferationGO:200056120.032
leukocyte degranulationGO:0043299270.032
intracellular protein transportGO:00068862040.032
exocytosisGO:00068871210.032
tumor necrosis factor superfamily cytokine productionGO:0071706510.032
regulation of exocytosisGO:0017157610.032
nuclear divisionGO:00002801580.032
cd4 positive alpha beta t cell activationGO:0035710450.032
negative regulation of myeloid cell apoptotic processGO:0033033110.031
divalent inorganic cation transportGO:00725111780.031
regulation of interleukin 8 productionGO:003267730.031
interleukin 18 mediated signaling pathwayGO:003565520.031
syncytium formation by plasma membrane fusionGO:0000768420.031
somatic diversification of immunoglobulinsGO:0016445430.031
Mouse
carbohydrate derivative biosynthetic processGO:19011371830.031
positive regulation of t helper 2 cell cytokine productionGO:200055330.031
alpha beta t cell differentiationGO:0046632690.031
purine containing compound metabolic processGO:00725213110.031
thymic t cell selectionGO:0045061220.031
Mouse
cell cell recognitionGO:0009988440.031
protein catabolic processGO:00301632210.031
signal transduction in absence of ligandGO:0038034550.030
regulation of peptide transportGO:0090087910.030
positive regulation of type 2 immune responseGO:000283090.030
peptide transportGO:00158331330.030
positive regulation of immune complex clearance by monocytes and macrophagesGO:009026520.030
cellular response to molecule of bacterial originGO:0071219830.030
negative regulation of peptidase activityGO:0010466460.030
organelle fissionGO:00482851700.030
notch signaling pathwayGO:0007219710.030
antimicrobial peptide productionGO:000277520.030
response to interleukin 15GO:007067230.030
positive regulation of immunoglobulin productionGO:0002639280.029
Mouse
nucleoside metabolic processGO:00091162460.029
cell divisionGO:00513011200.029
astrocyte cell migrationGO:004361530.029
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.029
cellular calcium ion homeostasisGO:00068741190.029
regulation of interleukin 8 secretionGO:200048220.029
positive regulation of transferase activityGO:00513471670.029
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.029
regulation of cellular catabolic processGO:00313292420.029
negative regulation of adaptive immune responseGO:0002820250.029
positive regulation of cell migrationGO:00303351090.029
purine ribonucleoside catabolic processGO:00461302050.028
positive regulation of dendritic cell dendrite assemblyGO:200054910.028
response to peptideGO:19016521360.028
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.028
morphogenesis of a branching structureGO:00017632030.028
regulation of leukocyte apoptotic processGO:2000106560.028
regulation of hematopoietic stem cell migrationGO:200047110.028
positive regulation of cell developmentGO:00107202370.028
regulation of tumor necrosis factor productionGO:0032680490.028
proteolysis involved in cellular protein catabolic processGO:00516031470.028
positive regulation of endothelial cell proliferationGO:0001938170.027
positive regulation of natural killer cell mediated immunityGO:0002717160.027
immune complex clearance by monocytes and macrophagesGO:000243620.027
immune response inhibiting signal transductionGO:000276540.027
positive regulation of cytoplasmic transportGO:1903651400.027
developmental maturationGO:00217001930.027
isotype switching to igg isotypesGO:0048291100.027
Mouse
cation homeostasisGO:00550802120.027
mammary gland morphogenesisGO:0060443540.027
nucleotide catabolic processGO:00091662170.027
positive regulation of kinase activityGO:00336741550.027
tolerance inductionGO:0002507140.027
muscle fiber developmentGO:0048747760.027
cellular nitrogen compound catabolic processGO:00442702800.027
regulation of striated muscle cell differentiationGO:0051153810.026
muscle cell differentiationGO:00426922610.026
ribose phosphate metabolic processGO:00196932910.026
positive regulation of nervous system developmentGO:00519622210.026
cytosolic calcium ion transportGO:0060401480.026
negative regulation of interferon gamma productionGO:0032689180.026
response to organonitrogen compoundGO:00102432460.026
negative regulation of cell cycleGO:00457861230.026
nucleoside triphosphate catabolic processGO:00091432050.026
purine ribonucleoside triphosphate metabolic processGO:00092052200.026
negative regulation of t cell proliferationGO:0042130380.026
regulation of myotube differentiationGO:0010830620.026
regulation of vascular endothelial growth factor productionGO:0010574130.026
negative regulation of leukocyte apoptotic processGO:2000107310.026
regulation of acute inflammatory responseGO:0002673270.026
regulation of ion transportGO:00432692150.026
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.026
Mouse
single organismal cell cell adhesionGO:00163371310.026
mapk cascadeGO:00001652810.026
protein localization to organelleGO:00333651850.026
detection of stimulusGO:0051606840.025
positive regulation of apoptotic signaling pathwayGO:2001235950.025
regulation of natural killer cell mediated cytotoxicityGO:0042269190.025
leukocyte homeostasisGO:0001776790.025

Ctla4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.065
Human
immune system diseaseDOID:291400.065
Human
disease of cellular proliferationDOID:1456600.028
organ system cancerDOID:005068600.028
cancerDOID:16200.028