Mus musculus

48 known processes

Cul5

cullin 5

(Aliases: C330021I08Rik,VACM-1,VACM1,8430423K24Rik,C030032G03Rik,4921514I20Rik,AI852817)

Cul5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720540.364
negative regulation of t helper 2 cell differentiationGO:004562940.276
regulation of activation of jak2 kinase activityGO:001053410.257
radial glia guided migration of purkinje cellGO:002194260.252
activation of janus kinase activityGO:004297620.242
layer formation in cerebral cortexGO:0021819130.218
regulation of activation of janus kinase activityGO:001053310.190
cellular amino acid metabolic processGO:00065201030.175
cerebral cortex radially oriented cell migrationGO:0021799310.151
negative regulation of tyrosine phosphorylation of stat3 proteinGO:004251810.120
regulation of cellular amino acid metabolic processGO:000652150.107
negative regulation of molecular functionGO:00440922580.103
cellular amine metabolic processGO:0044106440.102
negative regulation of cellular amino acid metabolic processGO:004576300.101
negative regulation of cellular amine metabolic processGO:003323910.099
g protein coupled receptor signaling pathwayGO:00071862430.099
amine metabolic processGO:0009308450.099
regulation of cellular amine metabolic processGO:0033238200.096
cerebral cortex cell migrationGO:0021795440.091
negative regulation of phosphorus metabolic processGO:00105631840.089
pallium developmentGO:00215431200.087
protein ubiquitinationGO:00165671710.082
cellular ketone metabolic processGO:0042180840.081
regulation of cd4 positive alpha beta t cell activationGO:2000514240.080
regulation of cellular ketone metabolic processGO:0010565660.079
hindbrain radial glia guided cell migrationGO:0021932120.078
positive regulation of t helper 1 cell differentiationGO:004562740.076
response to amino acidGO:0043200370.075
cd4 positive alpha beta t cell activationGO:0035710450.075
negative regulation of phosphate metabolic processGO:00459361840.074
protein modification by small protein conjugation or removalGO:00706472070.072
response to peptideGO:19016521360.072
cellular response to amino acid stimulusGO:0071230290.070
protein modification by small protein conjugationGO:00324461870.069
regulation of protein localizationGO:00328802310.066
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.063
cerebral cortex radial glia guided migrationGO:0021801170.062
negative regulation of insulin receptor signaling pathwayGO:0046627140.061
cytokine mediated signaling pathwayGO:00192211150.061
immune effector processGO:00022523210.060
negative regulation of protein modification processGO:00314001630.059
response to peptide hormoneGO:00434341270.057
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.057
regulation of kinase activityGO:00435492490.055
negative regulation of protein phosphorylationGO:00019331260.055
positive regulation of protein modification processGO:00314012990.054
negative regulation of protein metabolic processGO:00512482820.053
negative regulation of intracellular signal transductionGO:19025321670.052
forebrain cell migrationGO:0021885580.052
negative regulation of lymphocyte activationGO:0051250910.051
regulation of cytokine productionGO:00018172660.051
regulation of t helper cell differentiationGO:0045622140.051
leukocyte differentiationGO:00025213420.050
insulin receptor signaling pathwayGO:0008286490.050
negative regulation of tyrosine phosphorylation of stat proteinGO:004253230.050
negative regulation of defense responseGO:0031348770.049
positive regulation of transferase activityGO:00513471670.049
cellular response to acid chemicalGO:0071229680.049
regulation of establishment of protein localizationGO:00702011810.048
negative regulation of phosphorylationGO:00423261660.048
body fluid secretionGO:0007589530.048
regulation of transferase activityGO:00513382630.048
fat cell differentiationGO:00454441600.047
cellular response to insulin stimulusGO:0032869780.047
leukocyte activation involved in immune responseGO:00023661260.047
peptidyl amino acid modificationGO:00181933360.047
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.047
negative regulation of cd4 positive alpha beta t cell activationGO:2000515100.046
cellular response to hormone stimulusGO:00328701500.046
hindbrain developmentGO:00309021280.045
tyrosine phosphorylation of stat1 proteinGO:004250830.045
regulation of defense responseGO:00313472330.045
response to acid chemicalGO:00011011110.045
regulation of body fluid levelsGO:00508781620.045
lymphocyte differentiationGO:00300982420.044
positive regulation of kinase activityGO:00336741550.043
negative regulation of inflammatory responseGO:0050728610.043
regulation of secretionGO:00510462740.043
negative regulation of leukocyte differentiationGO:1902106510.043
regulation of secretion by cellGO:19035302490.043
spongiotrophoblast layer developmentGO:0060712150.042
inflammatory responseGO:00069542440.042
t helper cell differentiationGO:0042093280.041
negative regulation of alpha beta t cell activationGO:0046636180.041
regulation of protein kinase activityGO:00458592320.041
regulation of inflammatory responseGO:00507271470.041
regulation of neuron differentiationGO:00456642810.040
morphogenesis of a branching structureGO:00017632030.040
positive regulation of protein phosphorylationGO:00019342420.040
negative regulation of immune effector processGO:0002698550.040
negative regulation of immune system processGO:00026832090.039
negative regulation of cell activationGO:00508661110.039
response to organonitrogen compoundGO:00102432460.039
regulation of tyrosine phosphorylation of stat1 proteinGO:004251020.039
cellular response to cytokine stimulusGO:00713451890.039
regulation of response to woundingGO:19030341890.039
cerebral cortex developmentGO:0021987860.038
positive regulation of protein kinase activityGO:00458601440.037
cytokine productionGO:00018163190.037
cell activation involved in immune responseGO:00022631260.037
protein secretionGO:00093061110.036
cell differentiation involved in embryonic placenta developmentGO:0060706260.036
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.036
trophoblast giant cell differentiationGO:0060707150.036
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.036
negative regulation of cellular protein metabolic processGO:00322692470.035
male gamete generationGO:00482322850.035
peptidyl tyrosine phosphorylationGO:00181081430.035
regulation of t helper 1 cell differentiationGO:004562570.034
regulation of protein secretionGO:0050708820.034
positive regulation of nervous system developmentGO:00519622210.034
lymphocyte activation involved in immune responseGO:0002285930.034
jak stat cascadeGO:0007259420.034
regulation of alpha beta t cell activationGO:0046634530.034
negative regulation of response to woundingGO:1903035770.033
macromolecule catabolic processGO:00090572810.033
regulation of alpha beta t cell differentiationGO:0046637350.033
regulation of adaptive immune responseGO:0002819900.033
negative regulation of t cell activationGO:0050868650.033
placenta developmentGO:00018901400.033
lactationGO:0007595250.033
negative regulation of alpha beta t cell differentiationGO:0046639120.033
regulation of cell activationGO:00508652890.033
cellular response to peptideGO:1901653920.032
negative regulation of jak stat cascadeGO:004642670.032
cd4 positive alpha beta t cell differentiationGO:0043367410.032
spermatogenesisGO:00072832840.032
negative regulation of cellular response to insulin stimulusGO:1900077160.032
adaptive immune responseGO:00022501550.031
negative regulation of growthGO:0045926990.031
positive regulation of cell developmentGO:00107202370.030
peptidyl tyrosine modificationGO:00182121450.030
organonitrogen compound catabolic processGO:19015652640.030
glycosyl compound metabolic processGO:19016572460.029
mammary gland lobule developmentGO:0061377220.029
response to insulinGO:00328681000.029
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.029
positive regulation of adaptive immune responseGO:0002821610.028
cellular response to organonitrogen compoundGO:00714171450.028
purine nucleotide metabolic processGO:00061633020.028
forebrain developmentGO:00309003020.028
establishment of mitochondrion localizationGO:005165440.028
t cell activationGO:00421102890.028
positive regulation of immune effector processGO:00026991070.028
regulation of cytokine secretionGO:0050707610.028
regulation of peptidyl tyrosine phosphorylationGO:0050730930.028
alpha beta t cell differentiation involved in immune responseGO:0002293300.027
alpha beta t cell activationGO:0046631910.027
cellular response to peptide hormone stimulusGO:0071375920.027
negative regulation of lymphocyte differentiationGO:0045620320.027
purine ribonucleotide metabolic processGO:00091502900.027
t cell differentiation involved in immune responseGO:0002292300.026
cation transportGO:00068123990.026
membrane organizationGO:00610242450.025
regulation of protein transportGO:00512231630.025
organelle assemblyGO:00709251770.025
regulation of mapk cascadeGO:00434082480.025
embryonic placenta developmentGO:0001892980.025
positive regulation of alpha beta t cell differentiationGO:0046638280.025
negative regulation of t cell differentiationGO:0045581230.024
nitrogen compound transportGO:00717052710.024
oxidation reduction processGO:00551143420.024
multicellular organism growthGO:00352641610.024
nucleobase containing small molecule metabolic processGO:00550863520.023
t cell activation involved in immune responseGO:0002286430.023
nucleotide metabolic processGO:00091173320.023
heterocycle catabolic processGO:00467002800.023
positive regulation of lymphocyte activationGO:00512511400.022
striated muscle tissue developmentGO:00147062930.022
regulation of leukocyte differentiationGO:19021051590.022
alpha beta t cell differentiationGO:0046632690.022
gland developmentGO:00487323300.022
organophosphate catabolic processGO:00464342320.022
cellular response to dna damage stimulusGO:00069742070.021
aromatic compound catabolic processGO:00194392860.021
positive regulation of jak stat cascadeGO:0046427220.021
ribose phosphate metabolic processGO:00196932910.021
cytokine secretionGO:0050663720.020
regulation of t cell differentiationGO:0045580830.020
purine containing compound metabolic processGO:00725213110.020
organelle disassemblyGO:190300820.020
epidermal growth factor receptor signaling pathwayGO:0007173280.020
ribonucleoside metabolic processGO:00091192450.020
telencephalon developmentGO:00215371860.020
mammary gland alveolus developmentGO:0060749220.020
cellular nitrogen compound catabolic processGO:00442702800.020
regulation of type 2 immune responseGO:0002828180.020
positive regulation of leukocyte differentiationGO:1902107860.020
positive regulation of cell activationGO:00508671580.020
nucleoside phosphate metabolic processGO:00067533380.020
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.019
morphogenesis of a branching epitheliumGO:00611381930.019
positive regulation of alpha beta t cell activationGO:0046635390.019
lateral inhibitionGO:004633110.019
alpha beta t cell activation involved in immune responseGO:0002287310.019
regulation of jak stat cascadeGO:0046425340.019
erbb signaling pathwayGO:0038127320.019
regulation of lymphocyte activationGO:00512492400.019
posttranscriptional regulation of gene expressionGO:00106081550.019
regulation of t helper 2 cell differentiationGO:004562880.019
organic hydroxy compound metabolic processGO:19016152030.018
microtubule based processGO:00070172360.018
t cell differentiationGO:00302171740.018
nucleoside phosphate catabolic processGO:19012922220.018
purine ribonucleoside triphosphate catabolic processGO:00092071990.018
regulation of lymphocyte differentiationGO:00456191070.018
purine ribonucleotide catabolic processGO:00091542080.018
response to radiationGO:00093141650.018
ribonucleoside catabolic processGO:00424542060.018
intracellular mrna localizationGO:000829840.018
type 2 immune responseGO:0042092230.018
cognitionGO:00508901490.018
positive regulation of cd4 positive alpha beta t cell activationGO:2000516160.017
cellular protein catabolic processGO:00442571550.017
chromatin organizationGO:00063252060.017
response to organic cyclic compoundGO:00140701980.017
cellular macromolecule catabolic processGO:00442652060.017
mitochondrion distributionGO:004831140.017
cytoplasmic transportGO:00164822340.017
purine nucleoside metabolic processGO:00422782410.017
muscle tissue developmentGO:00605373080.017
skeletal muscle organ developmentGO:00605381630.017
methylationGO:00322591340.017
purine ribonucleoside catabolic processGO:00461302050.017
purine containing compound catabolic processGO:00725232130.017
positive regulation of cellular amine metabolic processGO:003324050.017
mitochondrion organizationGO:00070051340.017
ribonucleotide metabolic processGO:00092592910.017
purine ribonucleoside metabolic processGO:00461282410.017
positive regulation of t cell activationGO:00508701010.016
regulation of t helper 1 type immune responseGO:0002825170.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
lateral line system developmentGO:004892510.016
intracellular distribution of mitochondriaGO:004831210.016
nucleoside catabolic processGO:00091642060.016
retina development in camera type eyeGO:00600411190.016
mapk cascadeGO:00001652810.016
positive regulation of homeostatic processGO:0032846640.016
negative regulation of t helper cell differentiationGO:004562390.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
purine nucleoside triphosphate catabolic processGO:00091462030.016
positive regulation of necrotic cell deathGO:001094010.016
stem cell differentiationGO:00488632680.016
protein localization to organelleGO:00333651850.016
camera type eye developmentGO:00430102660.016
regulation of cellular catabolic processGO:00313292420.016
labyrinthine layer developmentGO:0060711490.015
tyrosine phosphorylation of stat proteinGO:0007260230.015
positive regulation of cellular amino acid metabolic processGO:004576430.015
t helper 1 cell differentiationGO:0045063130.015
nucleocytoplasmic transportGO:00069131390.015
regulation of organelle organizationGO:00330432890.015
oocyte axis specificationGO:000730920.015
t helper 1 type immune responseGO:0042088250.015
microtubule cytoskeleton organizationGO:00002261570.015
muscle cell differentiationGO:00426922610.015
learning or memoryGO:00076111480.015
organic cyclic compound catabolic processGO:19013612950.015
embryonic placenta morphogenesisGO:0060669250.015
telencephalon cell migrationGO:0022029550.014
compound eye developmentGO:004874910.014
microtubule slidingGO:005101210.014
mitochondrion transport along microtubuleGO:004749730.014
regulation of system processGO:00440572000.014
epithelial tube morphogenesisGO:00605623030.014
epithelial cell developmentGO:00020641590.014
mrna transportGO:0051028130.014
carbohydrate derivative catabolic processGO:19011362310.014
locomotory behaviorGO:00076261950.014
endomembrane system organizationGO:00102561470.014
ribonucleoside triphosphate metabolic processGO:00091992200.014
cellular homeostasisGO:00197252400.014
Rat
purine nucleoside catabolic processGO:00061522050.014
plasma membrane organizationGO:0007009900.014
regulation of homeostatic processGO:00328441820.014
regulation of membrane potentialGO:00423911920.013
protein catabolic processGO:00301632210.013
skeletal system developmentGO:00015013560.013
glycosyl compound catabolic processGO:19016582060.013
positive regulation of organelle organizationGO:00106381280.013
regulation of cell projection organizationGO:00313442060.013
nucleobase containing compound transportGO:0015931270.013
nucleoside metabolic processGO:00091162460.013
organonitrogen compound biosynthetic processGO:19015661920.013
cation transmembrane transportGO:00986552660.013
regulation of cell cycle processGO:00105641600.013
protein polymerizationGO:0051258570.013
regulation of cell motilityGO:20001452360.013
positive regulation of cd4 positive alpha beta t cell differentiationGO:0043372140.013
male meiosisGO:0007140370.013
striated muscle cell developmentGO:00550021250.013
dephosphorylationGO:00163111290.013
tyrosine phosphorylation of stat3 proteinGO:0042503120.013
regulation of cellular component biogenesisGO:00440871810.013
Fly
cellularizationGO:000734910.013
maintenance of locationGO:0051235890.013
stem cell developmentGO:00488642190.013
regulation of t cell activationGO:00508631700.012
nuclear transportGO:00511691390.012
regulation of mrna metabolic processGO:1903311430.012
positive regulation of t cell differentiationGO:0045582520.012
negative regulation of cell cycleGO:00457861230.012
nucleoside triphosphate metabolic processGO:00091412300.012
negative regulation of cellular component organizationGO:00511291940.012
nucleoside triphosphate catabolic processGO:00091432050.012
regulation of hydrolase activityGO:00513362460.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
sensory perceptionGO:00076002450.012
positive regulation of neuron differentiationGO:00456661410.012
regulation of synaptic growth at neuromuscular junctionGO:000858240.012
Fly
regulation of tyrosine phosphorylation of stat proteinGO:0042509200.012
cell cycle switching mitotic to meiotic cell cycleGO:005172810.012
rna processingGO:00063961050.012
protein localization to membraneGO:00726571080.012
regulation of ion transportGO:00432692150.012
sensory organ morphogenesisGO:00905962420.012
negative regulation of type 2 immune responseGO:000282980.012
atp metabolic processGO:0046034750.012
nuclear divisionGO:00002801580.012
regulation of cell migrationGO:00303342190.012
negative regulation of neuron differentiationGO:00456651010.012
germline cell cycle switching mitotic to meiotic cell cycleGO:005172910.012
oocyte constructionGO:000730820.012
multicellular organismal homeostasisGO:00488711640.012
regulation of anatomical structure sizeGO:00900661780.012
chromosome organization involved in meiosisGO:0070192390.012
branching involved in labyrinthine layer morphogenesisGO:006067090.011
nucleotide catabolic processGO:00091662170.011
ossificationGO:00015032160.011
regulation of cellular response to insulin stimulusGO:1900076300.011
transmission of nerve impulseGO:0019226760.011
multi multicellular organism processGO:00447061090.011
dna repairGO:00062811070.011
sensory system developmentGO:004888030.011
centrosome separationGO:005129940.011
rna localizationGO:0006403230.011
myosin filament assemblyGO:003103420.011
cellular protein complex assemblyGO:00436231160.011
reactive oxygen species metabolic processGO:0072593840.011
cellular chemical homeostasisGO:00550822150.011
Rat
establishment or maintenance of cytoskeleton polarityGO:003095220.011
apoptotic signaling pathwayGO:00971903060.011
regulation of neuron projection developmentGO:00109751690.011
ribonucleoside triphosphate catabolic processGO:00092031990.011
negative regulation of cell developmentGO:00107211690.011
response to alcoholGO:0097305480.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
macromolecule methylationGO:00434141200.011
regulation of cell cycleGO:00517262810.011
Fly
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
cellular component assembly involved in morphogenesisGO:00109271390.011
muscle cell developmentGO:00550011330.011
cellular response to lipidGO:00713961450.011
anion transportGO:00068201770.011
purine nucleoside monophosphate catabolic processGO:0009128580.011
anatomical structure homeostasisGO:00602491450.010
axis elongation involved in somitogenesisGO:009024540.010
inorganic ion transmembrane transportGO:00986602340.010
ribonucleotide catabolic processGO:00092612080.010
establishment of meiotic spindle orientationGO:005129610.010
placenta blood vessel developmentGO:0060674310.010
divalent metal ion transportGO:00708381720.010
ion transmembrane transportGO:00342203610.010
transmembrane transportGO:00550854120.010
limb developmentGO:00601731660.010
neural tube developmentGO:00219151600.010
labyrinthine layer morphogenesisGO:0060713210.010
inorganic cation transmembrane transportGO:00986622070.010
response to extracellular stimulusGO:00099911270.010
regulation of rna export from nucleusGO:004683140.010
protein targetingGO:00066051430.010
positive regulation of cell deathGO:00109422240.010
carbohydrate derivative biosynthetic processGO:19011371830.010
cofactor metabolic processGO:0051186800.010
regulation of proteolysisGO:00301621640.010
positive regulation of lymphocyte differentiationGO:0045621610.010

Cul5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.033
sensory system diseaseDOID:005015500.018
eye diseaseDOID:561400.018
eye and adnexa diseaseDOID:149200.018
immune system diseaseDOID:291400.018
organ system cancerDOID:005068600.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
hematopoietic system diseaseDOID:7400.011
retinal diseaseDOID:567900.011
musculoskeletal system diseaseDOID:1700.010