Mus musculus

0 known processes

Cldn18

claudin 18

Cldn18 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550854120.295
inorganic ion transmembrane transportGO:00986602340.275
cation transportGO:00068123990.273
ion transmembrane transportGO:00342203610.144
cation transmembrane transportGO:00986552660.118
immune effector processGO:00022523210.099
inflammatory responseGO:00069542440.078
defense response to bacteriumGO:00427421190.070
inorganic cation transmembrane transportGO:00986622070.066
regulation of secretionGO:00510462740.066
respiratory system developmentGO:00605411900.064
positive regulation of cellular amino acid metabolic processGO:004576430.062
anion transportGO:00068201770.057
anion transmembrane transportGO:0098656710.056
leukocyte activation involved in immune responseGO:00023661260.055
sodium ion transportGO:0006814730.052
negative regulation of growthGO:0045926990.052
regulation of vesicle mediated transportGO:00606271390.051
defense response to other organismGO:00985421970.050
interspecies interaction between organismsGO:0044419830.048
leukocyte migrationGO:00509001240.047
nitrogen compound transportGO:00717052710.047
renal system developmentGO:00720012250.046
regulation of defense responseGO:00313472330.045
regulation of adaptive immune responseGO:0002819900.044
cellular amine metabolic processGO:0044106440.044
cellular amino acid metabolic processGO:00065201030.043
cellular ketone metabolic processGO:0042180840.043
regulation of cellular catabolic processGO:00313292420.042
macromolecule catabolic processGO:00090572810.042
regulation of cellular amine metabolic processGO:0033238200.041
negative regulation of multi organism processGO:0043901680.040
regulation of cellular amino acid metabolic processGO:000652150.040
regulation of ion transportGO:00432692150.040
t cell differentiationGO:00302171740.040
response to amino acidGO:0043200370.039
positive regulation of cellular catabolic processGO:00313311480.038
cell type specific apoptotic processGO:00972852680.038
negative regulation of cell proliferationGO:00082852960.038
developmental growth involved in morphogenesisGO:00605601380.038
symbiosis encompassing mutualism through parasitismGO:0044403830.037
cell killingGO:0001906670.036
cellular response to lipidGO:00713961450.035
leukocyte mediated immunityGO:00024431740.035
regulation of cellular ketone metabolic processGO:0010565660.035
male gamete generationGO:00482322850.034
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.034
cellular response to biotic stimulusGO:0071216920.034
regulation of leukocyte mediated immunityGO:00027031040.034
positive regulation of defense responseGO:00313491240.033
protein catabolic processGO:00301632210.033
b cell activationGO:00421131610.033
chemotaxisGO:00069352470.033
positive regulation of secretionGO:00510471300.033
response to lipopolysaccharideGO:00324961280.032
leukocyte differentiationGO:00025213420.032
membrane organizationGO:00610242450.032
positive regulation of hydrolase activityGO:00513451480.031
positive regulation of protein phosphorylationGO:00019342420.031
positive regulation of cytokine productionGO:00018191740.031
lymphocyte differentiationGO:00300982420.030
response to molecule of bacterial originGO:00022371430.030
regulation of striated muscle cell differentiationGO:0051153810.029
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.029
positive regulation of leukocyte mediated immunityGO:0002705700.029
cellular response to molecule of bacterial originGO:0071219830.029
divalent metal ion transportGO:00708381720.028
cation homeostasisGO:00550802120.028
neuron projection guidanceGO:00974851410.028
positive regulation of protein modification processGO:00314012990.028
regulation of muscle tissue developmentGO:1901861970.028
response to organic cyclic compoundGO:00140701980.028
single organism cell adhesionGO:00986021560.027
regulation of neuron projection developmentGO:00109751690.027
regulation of establishment of protein localizationGO:00702011810.027
connective tissue developmentGO:00614481790.027
skeletal system morphogenesisGO:00487052030.027
positive regulation of cell motilityGO:20001471160.027
cytokine productionGO:00018163190.026
regulation of phospholipase a2 activityGO:003242930.026
sequestering of metal ionGO:0051238190.026
regulation of cardiac muscle tissue growthGO:0055021260.026
ribonucleotide metabolic processGO:00092592910.026
stem cell differentiationGO:00488632680.026
regulation of cell migrationGO:00303342190.026
action potentialGO:0001508780.026
homeostasis of number of cellsGO:00488722100.026
innate immune responseGO:00450871570.026
regulation of neuron differentiationGO:00456642810.026
t cell activationGO:00421102890.025
peptide transportGO:00158331330.025
g protein coupled receptor signaling pathwayGO:00071862430.025
ras protein signal transductionGO:0007265770.025
regulation of mitotic cell cycleGO:00073461260.025
alpha beta t cell activationGO:0046631910.025
lymphocyte activation involved in immune responseGO:0002285930.025
cell activation involved in immune responseGO:00022631260.025
regulation of protein maturationGO:1903317960.025
positive regulation of immune effector processGO:00026991070.025
interferon gamma productionGO:0032609670.024
ossificationGO:00015032160.024
regulation of extent of cell growthGO:0061387520.024
leukocyte homeostasisGO:0001776790.024
oviduct developmentGO:006006630.024
organ growthGO:00352651170.024
adaptive immune responseGO:00022501550.024
urogenital system developmentGO:00016552610.024
positive regulation of protein transportGO:0051222930.023
regulation of transmembrane transportGO:00347621280.023
cellular ion homeostasisGO:00068731650.023
response to acid chemicalGO:00011011110.023
regulation of neuron apoptotic processGO:00435231220.023
regulation of lymphocyte mediated immunityGO:0002706840.023
positive regulation of reactive oxygen species metabolic processGO:2000379110.023
regulation of lymphocyte activationGO:00512492400.023
peptidyl amino acid modificationGO:00181933360.023
sodium ion transmembrane transportGO:0035725490.023
posttranscriptional regulation of gene expressionGO:00106081550.023
positive regulation of cellular amine metabolic processGO:003324050.022
lung developmentGO:00303241640.022
regulation of protein localizationGO:00328802310.022
morphogenesis of a branching epitheliumGO:00611381930.022
regulation of ion transmembrane transporter activityGO:0032412540.022
transmission of nerve impulseGO:0019226760.022
cellular response to acid chemicalGO:0071229680.022
activation of immune responseGO:00022531380.022
negative regulation of molecular functionGO:00440922580.022
regulation of cell cycleGO:00517262810.022
neuron deathGO:00709971540.021
lymphocyte mediated immunityGO:00024491390.021
alpha beta t cell differentiationGO:0046632690.021
positive regulation of apoptotic processGO:00430652170.021
calcium ion transportGO:00068161590.021
response to extracellular stimulusGO:00099911270.021
ribonucleoside catabolic processGO:00424542060.021
nucleoside metabolic processGO:00091162460.021
peptide hormone secretionGO:00300721090.021
b cell differentiationGO:0030183780.021
regulation of cell motilityGO:20001452360.021
regulation of intracellular transportGO:00323861590.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.021
sequestering of calcium ionGO:0051208180.020
regulation of multi organism processGO:00439001110.020
regulation of protein catabolic processGO:00421761080.020
negative regulation of cell fate specificationGO:000999640.020
myotube differentiationGO:00149021050.020
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.020
response to organonitrogen compoundGO:00102432460.020
regulation of bindingGO:00510981110.020
glucosamine containing compound metabolic processGO:190107130.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.020
killing of cells of other organismGO:0031640130.020
negative regulation of cellular component organizationGO:00511291940.020
regulation of cell sizeGO:0008361720.020
somatotropin secreting cell differentiationGO:006012640.020
myeloid leukocyte mediated immunityGO:0002444420.020
wnt signaling pathwayGO:00160551880.019
apoptotic signaling pathwayGO:00971903060.019
endodermal cell fate specificationGO:000171440.019
ribose phosphate metabolic processGO:00196932910.019
regulation of innate immune responseGO:0045088910.019
single organismal cell cell adhesionGO:00163371310.019
cellular metal ion homeostasisGO:00068751510.019
regulation of t cell activationGO:00508631700.019
reactive oxygen species metabolic processGO:0072593840.019
divalent inorganic cation transportGO:00725111780.019
positive regulation of innate immune responseGO:0045089800.019
maintenance of locationGO:0051235890.019
positive regulation of interleukin 8 productionGO:003275720.018
male genitalia morphogenesisGO:004880840.018
mapk cascadeGO:00001652810.018
cd4 positive alpha beta t cell differentiationGO:0043367410.018
amide transportGO:00428861380.018
positive regulation of cell migrationGO:00303351090.018
regulation of ras protein signal transductionGO:00465781140.018
leukocyte mediated cytotoxicityGO:0001909620.018
small gtpase mediated signal transductionGO:0007264970.018
multicellular organismal signalingGO:0035637910.018
potassium ion transmembrane transportGO:0071805430.018
lipid localizationGO:00108761260.018
epithelial cell proliferationGO:00506731740.018
positive regulation of neuron differentiationGO:00456661410.018
amine metabolic processGO:0009308450.018
protein modification by small protein conjugationGO:00324461870.018
cell growthGO:00160491300.018
organic anion transportGO:00157111370.018
telencephalon developmentGO:00215371860.018
aromatic compound catabolic processGO:00194392860.017
cellular response to external stimulusGO:0071496880.017
myeloid leukocyte differentiationGO:00025731190.017
lateral inhibitionGO:004633110.017
nucleoside phosphate metabolic processGO:00067533380.017
regulation of reactive oxygen species metabolic processGO:2000377400.017
cellular response to cytokine stimulusGO:00713451890.017
nucleotide metabolic processGO:00091173320.017
exocytosisGO:00068871210.017
positive regulation of plasminogen activationGO:001075620.017
planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:006134920.017
epithelial tube formationGO:00721751300.017
protein modification by small protein conjugation or removalGO:00706472070.017
mesodermal cell migrationGO:000807840.017
negative regulation of cell developmentGO:00107211690.017
regulation of inflammatory responseGO:00507271470.017
regulation of t cell differentiationGO:0045580830.017
positive regulation of protein kinase activityGO:00458601440.017
regulation of cell morphogenesis involved in differentiationGO:00107691510.017
peptidyl tyrosine modificationGO:00182121450.017
gonad developmentGO:00084061410.017
myeloid cell differentiationGO:00300992330.017
t cell mediated immunityGO:0002456500.017
lung alveolus developmentGO:0048286450.016
positive regulation of proteolysisGO:0045862850.016
regulation of body fluid levelsGO:00508781620.016
signal transduction in absence of ligandGO:0038034550.016
nerve developmentGO:0021675670.016
carnitine transportGO:001587930.016
appendage morphogenesisGO:00351071490.016
wound healingGO:00420601570.016
ear developmentGO:00435832000.016
sterol homeostasisGO:0055092450.016
positive regulation of cell deathGO:00109422240.016
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.016
non canonical wnt signaling pathway involved in heart developmentGO:006134130.016
striated muscle tissue developmentGO:00147062930.016
positive regulation of cell developmentGO:00107202370.016
potassium ion transportGO:0006813520.016
stem cell maintenanceGO:00198271300.016
regulation of ion transmembrane transportGO:00347651190.016
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.016
regulation of peptide transportGO:0090087910.016
muscle cell differentiationGO:00426922610.016
neuromuscular processGO:0050905990.016
axonogenesisGO:00074092740.016
amino acid transmembrane transportGO:0003333370.016
regulation of protein processingGO:0070613960.016
cellular response to growth factor stimulusGO:00713631970.016
regulation of organ growthGO:0046620610.016
t cell activation involved in immune responseGO:0002286430.015
regulation of secretion by cellGO:19035302490.015
gland developmentGO:00487323300.015
smoothened signaling pathwayGO:00072241050.015
neuron projection extensionGO:1990138640.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
protein ubiquitinationGO:00165671710.015
purine nucleoside metabolic processGO:00422782410.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.015
regulation of neuron deathGO:19012141340.015
cd4 positive alpha beta t cell activationGO:0035710450.015
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.015
neuron apoptotic processGO:00514021420.015
calcium ion transmembrane transportGO:0070588850.015
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.015
regulation of reactive oxygen species biosynthetic processGO:190342620.015
tube formationGO:00351481400.015
inorganic anion transmembrane transportGO:0098661290.015
mesonephric duct formationGO:007218120.015
regulation of cell activationGO:00508652890.015
positive regulation of neuron projection developmentGO:0010976790.015
muscle fiber developmentGO:0048747760.015
regulation of response to woundingGO:19030341890.015
regulation of protein kinase activityGO:00458592320.015
organic hydroxy compound transportGO:0015850930.015
negative regulation of cellular protein metabolic processGO:00322692470.015
lipid transportGO:0006869980.014
organic cyclic compound catabolic processGO:19013612950.014
production of molecular mediator of immune responseGO:00024401030.014
skeletal system developmentGO:00015013560.014
regulation of syncytium formation by plasma membrane fusionGO:0060142230.014
limb morphogenesisGO:00351081490.014
carbohydrate metabolic processGO:00059752300.014
bundle of his developmentGO:000316640.014
negative regulation of cell cycleGO:00457861230.014
positive regulation of secretion by cellGO:19035321140.014
respiratory tube developmentGO:00303231670.014
purine ribonucleotide metabolic processGO:00091502900.014
response to nutrient levelsGO:00316671090.014
skeletal muscle organ developmentGO:00605381630.014
organelle localizationGO:00516401790.014
chloride transmembrane transportGO:1902476240.014
cytokine secretionGO:0050663720.014
cardiocyte differentiationGO:0035051870.014
nucleobase containing small molecule metabolic processGO:00550863520.014
positive regulation of stem cell proliferationGO:2000648590.014
positive regulation of phospholipase activityGO:001051830.014
striated muscle cell developmentGO:00550021250.014
circulatory system processGO:00030131970.014
protein maturationGO:00516041760.014
negative regulation of intracellular signal transductionGO:19025321670.014
negative regulation of immune system processGO:00026832090.014
defense response to virusGO:0051607680.014
microtubule based processGO:00070172360.014
cellular potassium ion transportGO:0071804430.014
regulation of cardioblast differentiationGO:005189030.014
regulation of cell growthGO:0001558910.014
negative regulation of hormone metabolic processGO:003235140.014
protein localization to membraneGO:00726571080.014
regulation of myotube differentiationGO:0010830620.014
response to vitamin aGO:003318910.014
regulation of cellular response to stressGO:00801351590.013
cell maturationGO:00484691270.013
cellular response to lipopolysaccharideGO:0071222770.013
cytokine metabolic processGO:0042107710.013
tissue homeostasisGO:00018941150.013
positive regulation of organelle organizationGO:00106381280.013
regulation of purine nucleotide metabolic processGO:19005421690.013
ribonucleoside metabolic processGO:00091192450.013
negative regulation of synapse assemblyGO:005196430.013
bronchiole developmentGO:006043530.013
syncytium formationGO:0006949430.013
mesenchyme developmentGO:00604851520.013
purine containing compound metabolic processGO:00725213110.013
regulation of lymphocyte differentiationGO:00456191070.013
body fluid secretionGO:0007589530.013
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.013
reactive nitrogen species metabolic processGO:200105700.013
positive regulation of purine nucleotide catabolic processGO:0033123880.013
multicellular organismal homeostasisGO:00488711640.013
sensory perceptionGO:00076002450.013
regulation of cytokine productionGO:00018172660.013
regulation of leukocyte differentiationGO:19021051590.013
kidney developmentGO:00018222130.013
positive regulation of protein secretionGO:0050714520.013
tissue remodelingGO:00487711020.013
spermatogenesisGO:00072832840.013
positive regulation of t cell activationGO:00508701010.013
regulation of interferon gamma productionGO:0032649570.013
response to epidermal growth factorGO:007084940.013
engulfment of apoptotic cellGO:004365230.013
monocarboxylic acid transportGO:0015718440.013
regulation of skeletal muscle fiber developmentGO:0048742360.013
synaptic transmissionGO:00072683290.012
cellular response to dna damage stimulusGO:00069742070.012
cellular response to organonitrogen compoundGO:00714171450.012
cellular homeostasisGO:00197252400.012
positive regulation of cell activationGO:00508671580.012
dna recombinationGO:0006310920.012
metanephric loop of henle developmentGO:007223640.012
endocytosisGO:00068971680.012
metal ion homeostasisGO:00550651890.012
purine ribonucleoside metabolic processGO:00461282410.012
myeloid leukocyte activationGO:0002274830.012
cellular chemical homeostasisGO:00550822150.012
regulation of system processGO:00440572000.012
cellular response to amino acid stimulusGO:0071230290.012
purine nucleoside triphosphate metabolic processGO:00091442260.012
regulation of axon extensionGO:0030516430.012
peptidyl tyrosine phosphorylationGO:00181081430.012
glycosyl compound catabolic processGO:19016582060.012
midbrain hindbrain boundary maturation during brain developmentGO:002200410.012
development of primary sexual characteristicsGO:00451371430.012
glycosyl compound metabolic processGO:19016572460.012
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.012
purine nucleotide catabolic processGO:00061952110.012
his purkinje system developmentGO:000316440.012
trabecula morphogenesisGO:0061383400.012
regulation of metal ion transportGO:00109591060.012
oxygen homeostasisGO:003236420.012
locomotory behaviorGO:00076261950.012
positive regulation of voltage gated calcium channel activityGO:190138720.012
response to starvationGO:0042594650.012
regulation of apoptotic signaling pathwayGO:20012331970.012
regulation of hydrolase activityGO:00513362460.012
regulation of cell cycle processGO:00105641600.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
branch elongation involved in salivary gland morphogenesisGO:006066720.012
ventral spinal cord developmentGO:0021517480.012
positive regulation of wnt signaling pathwayGO:0030177450.012
positive regulation of muscle cell differentiationGO:0051149390.012
microtubule cytoskeleton organizationGO:00002261570.012
mitotic cell cycleGO:00002781950.012
foregut regionalizationGO:006042330.012
regulation of wnt signaling pathwayGO:00301111230.012
hematopoietic progenitor cell differentiationGO:00022441430.012
stem cell proliferationGO:00720891170.012
muscle cell proliferationGO:0033002520.012
negative regulation of neuron projection developmentGO:0010977500.012
morphogenesis of embryonic epitheliumGO:00163311590.012
otic placode formationGO:004304910.012
cellular protein catabolic processGO:00442571550.012
muscle cell developmentGO:00550011330.012
positive regulation of protein catabolic processGO:0045732600.012
protein processingGO:00164851630.011
protein localization to nucleusGO:00345041210.011
forebrain developmentGO:00309003020.011
positive regulation of lymphocyte mediated immunityGO:0002708620.011
skin developmentGO:00435882200.011
nucleotide catabolic processGO:00091662170.011
positive regulation of epithelial cell proliferation involved in lung morphogenesisGO:006050130.011
purine containing compound biosynthetic processGO:0072522700.011
nucleoside catabolic processGO:00091642060.011
positive regulation of response to woundingGO:1903036660.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
lung epithelium developmentGO:0060428370.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
ribonucleotide catabolic processGO:00092612080.011
negative regulation of cell migrationGO:0030336590.011
positive regulation of rho gtpase activityGO:0032321410.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
negative regulation of neuron differentiationGO:00456651010.011
lung pattern specification processGO:006043210.011
epithelial cell developmentGO:00020641590.011
purine ribonucleoside catabolic processGO:00461302050.011
regulation of peptidyl tyrosine phosphorylationGO:0050730930.011
negative regulation of protein metabolic processGO:00512482820.011
intracellular protein transportGO:00068862040.011
phospholipid metabolic processGO:0006644870.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
regulation of cellular component sizeGO:00325351210.011
regulation of reproductive processGO:2000241660.011
regulation of protein ubiquitinationGO:0031396520.011
carbohydrate derivative biosynthetic processGO:19011371830.011
positive regulation of phagocytosis engulfmentGO:006010030.011
regulation of organelle organizationGO:00330432890.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
regulation of wound healingGO:0061041400.011
ribonucleoside triphosphate metabolic processGO:00091992200.011
epithelial tube morphogenesisGO:00605623030.011
bone developmentGO:00603481200.011
cellular nitrogen compound catabolic processGO:00442702800.011
negative regulation of muscle cell differentiationGO:0051148330.011
toxin transportGO:1901998380.011
response to oxygen levelsGO:0070482620.011
regulation of ion homeostasisGO:2000021640.011
regulation of cardiac muscle cell proliferationGO:0060043230.011
fertilizationGO:00095661270.011
morphogenesis of an epithelial sheetGO:0002011270.011
regulation of kinase activityGO:00435492490.011
extracellular structure organizationGO:00430621480.011
negative regulation of cellular amine metabolic processGO:003323910.011
blood vessel remodelingGO:0001974330.011
blood circulationGO:00080151950.011
skeletal muscle fiber developmentGO:0048741580.011
multicellular organism growthGO:00352641610.011
cellular protein complex assemblyGO:00436231160.010
myoblast differentiationGO:0045445520.010
negative regulation of cell activationGO:00508661110.010
regulation of cell divisionGO:0051302760.010
lipid homeostasisGO:0055088630.010
sensory neuron axon guidanceGO:009737430.010
anatomical structure homeostasisGO:00602491450.010
regulation of anatomical structure sizeGO:00900661780.010
notch signaling pathwayGO:0007219710.010
mammary gland morphogenesisGO:0060443540.010
endochondral bone morphogenesisGO:0060350500.010
developmental cell growthGO:0048588840.010
angiogenesisGO:00015252010.010
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferationGO:200008110.010
mitochondrion organizationGO:00070051340.010
viral gene expressionGO:001908030.010
positive regulation of branching involved in lung morphogenesisGO:006104740.010
production of molecular mediator involved in inflammatory responseGO:0002532210.010
stem cell developmentGO:00488642190.010
defense response to gram positive bacteriumGO:0050830500.010
negative regulation of phosphorus metabolic processGO:00105631840.010
regulation of protein modification by small protein conjugation or removalGO:1903320570.010
regulation of cardiac chamber morphogenesisGO:190121920.010
organonitrogen compound biosynthetic processGO:19015661920.010

Cldn18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
respiratory system diseaseDOID:157900.030
disease of anatomical entityDOID:700.030
disease of metabolismDOID:001466700.018