Mus musculus

82 known processes

Lims2

LIM and senescent cell antigen like domains 2

(Aliases: PINCH2)

Lims2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleobase containing small molecule metabolic processGO:00550863520.114
nucleoside phosphate metabolic processGO:00067533380.113
negative regulation of phosphorus metabolic processGO:00105631840.099
Fly
cellular ketone metabolic processGO:0042180840.092
nucleotide metabolic processGO:00091173320.087
negative regulation of cellular protein metabolic processGO:00322692470.083
oxidation reduction processGO:00551143420.080
regulation of cellular ketone metabolic processGO:0010565660.077
organic cyclic compound catabolic processGO:19013612950.077
purine nucleotide metabolic processGO:00061633020.071
negative regulation of phosphorylationGO:00423261660.070
Fly
regulation of cellular amino acid metabolic processGO:000652150.070
fat cell differentiationGO:00454441600.062
Mouse
purine containing compound metabolic processGO:00725213110.061
ribonucleotide metabolic processGO:00092592910.060
cellular amino acid metabolic processGO:00065201030.058
negative regulation of protein metabolic processGO:00512482820.058
regulation of hydrolase activityGO:00513362460.054
aromatic compound catabolic processGO:00194392860.054
organonitrogen compound catabolic processGO:19015652640.053
carbohydrate metabolic processGO:00059752300.052
ion transmembrane transportGO:00342203610.051
lipid biosynthetic processGO:00086101790.049
cellular response to organonitrogen compoundGO:00714171450.049
amine metabolic processGO:0009308450.048
regulation of cellular amine metabolic processGO:0033238200.048
heterocycle catabolic processGO:00467002800.048
purine ribonucleotide metabolic processGO:00091502900.048
cellular amine metabolic processGO:0044106440.047
macromolecule catabolic processGO:00090572810.046
Worm
regulation of kinase activityGO:00435492490.046
Mouse
negative regulation of cellular amine metabolic processGO:003323910.045
negative regulation of molecular functionGO:00440922580.045
ribonucleotide catabolic processGO:00092612080.044
nucleoside triphosphate metabolic processGO:00091412300.043
purine nucleoside catabolic processGO:00061522050.043
ribose phosphate metabolic processGO:00196932910.043
small gtpase mediated signal transductionGO:0007264970.043
epithelial cell developmentGO:00020641590.042
cell adhesionGO:00071553290.042
lipid localizationGO:00108761260.041
Worm
nucleoside metabolic processGO:00091162460.041
gland developmentGO:00487323300.041
ribonucleoside metabolic processGO:00091192450.041
negative regulation of phosphate metabolic processGO:00459361840.040
Fly
purine ribonucleoside metabolic processGO:00461282410.039
transmembrane transportGO:00550854120.039
response to organonitrogen compoundGO:00102432460.039
purine containing compound catabolic processGO:00725232130.039
purine nucleotide catabolic processGO:00061952110.039
maintenance of locationGO:0051235890.038
Worm
anion transportGO:00068201770.038
organic anion transportGO:00157111370.038
cellular nitrogen compound catabolic processGO:00442702800.038
negative regulation of cell proliferationGO:00082852960.037
ribonucleoside triphosphate metabolic processGO:00091992200.036
negative regulation of protein modification processGO:00314001630.035
regulation of transferase activityGO:00513382630.035
Mouse
purine ribonucleoside catabolic processGO:00461302050.035
nucleoside catabolic processGO:00091642060.035
negative regulation of cellular amino acid metabolic processGO:004576300.034
purine nucleoside triphosphate catabolic processGO:00091462030.034
regulation of protein kinase activityGO:00458592320.034
Mouse
nitrogen compound transportGO:00717052710.034
regulation of proteolysisGO:00301621640.034
cellular homeostasisGO:00197252400.034
glycosyl compound catabolic processGO:19016582060.034
sensory perceptionGO:00076002450.034
Worm
purine nucleoside metabolic processGO:00422782410.033
protein catabolic processGO:00301632210.033
Worm
negative regulation of protein phosphorylationGO:00019331260.033
nucleotide catabolic processGO:00091662170.032
organophosphate catabolic processGO:00464342320.032
regulation of membrane potentialGO:00423911920.032
glycosyl compound metabolic processGO:19016572460.032
regulation of anatomical structure sizeGO:00900661780.031
generation of precursor metabolites and energyGO:00060911030.031
purine nucleoside triphosphate metabolic processGO:00091442260.031
regulation of protein serine threonine kinase activityGO:00719001570.031
Mouse
cation transportGO:00068123990.030
camera type eye developmentGO:00430102660.030
regulation of organelle organizationGO:00330432890.030
regulation of cellular component biogenesisGO:00440871810.030
organic hydroxy compound metabolic processGO:19016152030.030
ribonucleoside catabolic processGO:00424542060.029
negative regulation of cellular component organizationGO:00511291940.029
developmental growth involved in morphogenesisGO:00605601380.029
endocytosisGO:00068971680.028
Worm
regulation of lipid metabolic processGO:00192161180.028
peptidyl amino acid modificationGO:00181933360.028
Mouse
organonitrogen compound biosynthetic processGO:19015661920.027
purine ribonucleoside triphosphate metabolic processGO:00092052200.027
response to growth factorGO:00708481980.027
Mouse
positive regulation of mapk cascadeGO:00434101700.027
Mouse
chemotaxisGO:00069352470.026
regulation of cellular catabolic processGO:00313292420.026
energy derivation by oxidation of organic compoundsGO:0015980770.026
cellular carbohydrate metabolic processGO:00442621190.026
membrane organizationGO:00610242450.026
nucleoside phosphate catabolic processGO:19012922220.026
cellular lipid metabolic processGO:00442553230.025
cofactor metabolic processGO:0051186800.025
transmission of nerve impulseGO:0019226760.025
response to organic cyclic compoundGO:00140701980.025
regulation of purine nucleotide metabolic processGO:19005421690.025
regulation of cell morphogenesis involved in differentiationGO:00107691510.025
positive regulation of hydrolase activityGO:00513451480.024
microtubule based processGO:00070172360.024
male gamete generationGO:00482322850.024
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.024
purine ribonucleotide catabolic processGO:00091542080.024
action potentialGO:0001508780.024
positive regulation of protein kinase activityGO:00458601440.024
Mouse
inflammatory responseGO:00069542440.023
monocarboxylic acid metabolic processGO:00327871910.023
actin filament organizationGO:00070151130.023
blood circulationGO:00080151950.023
Zebrafish
immune effector processGO:00022523210.023
circulatory system processGO:00030131970.023
Zebrafish
purine ribonucleoside triphosphate catabolic processGO:00092071990.023
inorganic ion transmembrane transportGO:00986602340.023
gtp metabolic processGO:00460391440.023
neuronal action potentialGO:0019228540.022
cellular response to hormone stimulusGO:00328701500.022
positive regulation of apoptotic processGO:00430652170.022
positive regulation of programmed cell deathGO:00430682180.022
regulation of hormone levelsGO:00108172110.022
small molecule biosynthetic processGO:00442831320.022
regulation of fat cell differentiationGO:0045598810.022
Mouse
sensory organ morphogenesisGO:00905962420.022
regulation of system processGO:00440572000.022
cation transmembrane transportGO:00986552660.022
skeletal system developmentGO:00015013560.022
response to peptide hormoneGO:00434341270.022
cellular response to peptideGO:1901653920.022
positive regulation of protein modification processGO:00314012990.022
Mouse
positive regulation of cellular component biogenesisGO:0044089940.022
cell junction assemblyGO:0034329520.022
Mouse
regulation of secretion by cellGO:19035302490.022
cell junction organizationGO:0034330770.021
protein localization to membraneGO:00726571080.021
respiratory tube developmentGO:00303231670.021
regulation of mapk cascadeGO:00434082480.021
Mouse Fly
inorganic cation transmembrane transportGO:00986622070.021
ribonucleoside triphosphate catabolic processGO:00092031990.021
glucose metabolic processGO:0006006920.021
regulation of nucleotide metabolic processGO:00061401690.021
positive regulation of protein phosphorylationGO:00019342420.021
Mouse
regulation of cell activationGO:00508652890.021
amide transportGO:00428861380.020
regulation of map kinase activityGO:00434051200.020
Mouse
multicellular organismal signalingGO:0035637910.020
cell cell junction organizationGO:0045216720.020
mapk cascadeGO:00001652810.020
Mouse Fly
g protein coupled receptor signaling pathwayGO:00071862430.020
carbohydrate derivative biosynthetic processGO:19011371830.020
monosaccharide metabolic processGO:00059961060.020
cell matrix adhesionGO:0007160680.020
Mouse
monosaccharide transportGO:0015749580.020
organophosphate biosynthetic processGO:00904071220.020
renal system developmentGO:00720012250.019
glycerolipid metabolic processGO:00464861220.019
epithelial tube morphogenesisGO:00605623030.019
Mouse
spermatogenesisGO:00072832840.019
regulation of actin filament based processGO:0032970990.019
protein maturationGO:00516041760.019
regulation of cell adhesionGO:00301551540.019
positive regulation of transferase activityGO:00513471670.019
Mouse
cell growthGO:00160491300.019
carbohydrate derivative catabolic processGO:19011362310.019
plasma membrane organizationGO:0007009900.019
actin cytoskeleton organizationGO:00300362200.019
Mouse
hexose metabolic processGO:0019318980.019
regulation of secretionGO:00510462740.019
cellular protein complex assemblyGO:00436231160.019
regulation of nucleoside metabolic processGO:00091181300.019
regulation of cell projection organizationGO:00313442060.018
regulation of inflammatory responseGO:00507271470.018
regulation of defense responseGO:00313472330.018
protein processingGO:00164851630.018
response to transforming growth factor betaGO:0071559880.018
Mouse
embryonic organ morphogenesisGO:00485622760.018
organic acid transportGO:00158491010.018
reactive oxygen species metabolic processGO:0072593840.018
actin filament based movementGO:0030048230.018
positive regulation of cellular amine metabolic processGO:003324050.018
regulation of cytoskeleton organizationGO:00514931220.018
positive regulation of purine nucleotide metabolic processGO:19005441140.018
regulation of neuron differentiationGO:00456642810.018
cellular response to peptide hormone stimulusGO:0071375920.018
regulation of nucleotide catabolic processGO:00308111220.018
positive regulation of cell deathGO:00109422240.018
regulation of cell motilityGO:20001452360.018
negative regulation of kinase activityGO:0033673810.018
positive regulation of cellular catabolic processGO:00313311480.018
hormone secretionGO:00468791280.017
response to molecule of bacterial originGO:00022371430.017
multicellular organism growthGO:00352641610.017
regulation of apoptotic signaling pathwayGO:20012331970.017
endomembrane system organizationGO:00102561470.017
cell substrate adhesionGO:00315891300.017
Mouse
fatty acid metabolic processGO:00066311210.017
regulation of lipid biosynthetic processGO:0046890540.017
cellular response to insulin stimulusGO:0032869780.017
positive regulation of cell developmentGO:00107202370.017
regulation of glucose metabolic processGO:0010906600.017
cellular macromolecule catabolic processGO:00442652060.017
alcohol metabolic processGO:00060661160.017
rho protein signal transductionGO:0007266320.017
nucleoside triphosphate catabolic processGO:00091432050.017
carbohydrate homeostasisGO:00335001280.017
cell fate commitmentGO:00451652100.016
Mouse
reactive nitrogen species metabolic processGO:200105700.016
liver developmentGO:0001889660.016
coenzyme metabolic processGO:0006732520.016
microtubule cytoskeleton organizationGO:00002261570.016
blood vessel morphogenesisGO:00485142850.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.016
Mouse
regulation of cell growthGO:0001558910.016
neutral lipid metabolic processGO:0006638570.016
lung developmentGO:00303241640.016
axonogenesisGO:00074092740.016
regulation of endopeptidase activityGO:0052548890.016
insulin receptor signaling pathwayGO:0008286490.015
response to radiationGO:00093141650.015
hepaticobiliary system developmentGO:0061008670.015
muscle tissue developmentGO:00605373080.015
regulation of cell migrationGO:00303342190.015
ribonucleoside monophosphate metabolic processGO:0009161800.015
regulation of response to woundingGO:19030341890.015
multicellular organismal homeostasisGO:00488711640.015
morphogenesis of a branching structureGO:00017632030.015
Mouse
carboxylic acid transportGO:00469421000.015
mitochondrion organizationGO:00070051340.015
regulation of actin cytoskeleton organizationGO:0032956840.015
cognitionGO:00508901490.015
skeletal system morphogenesisGO:00487052030.015
nucleoside phosphate biosynthetic processGO:1901293790.015
t cell activationGO:00421102890.015
muscle contractionGO:00069361010.015
Worm
kidney developmentGO:00018222130.015
muscle system processGO:00030121410.015
Worm
epithelial cell proliferationGO:00506731740.015
protein kinase b signalingGO:0043491740.015
Zebrafish
glucose homeostasisGO:00425931280.015
intracellular protein transportGO:00068862040.015
cell type specific apoptotic processGO:00972852680.015
heart processGO:0003015940.015
Zebrafish
negative regulation of transferase activityGO:0051348850.015
regulation of cellular carbohydrate metabolic processGO:0010675750.015
innate immune responseGO:00450871570.015
forebrain developmentGO:00309003020.015
kidney epithelium developmentGO:00720731210.015
mitotic cell cycleGO:00002781950.015
negative regulation of proteolysisGO:0045861740.015
positive regulation of cellular amino acid metabolic processGO:004576430.014
positive regulation of steroid biosynthetic processGO:001089340.014
regulation of establishment of protein localizationGO:00702011810.014
response to peptideGO:19016521360.014
synaptic transmissionGO:00072683290.014
gliogenesisGO:00420631410.014
positive regulation of nucleotide metabolic processGO:00459811140.014
atp metabolic processGO:0046034750.014
homeostasis of number of cellsGO:00488722100.014
organic acid biosynthetic processGO:0016053860.014
peptide transportGO:00158331330.014
posttranscriptional regulation of gene expressionGO:00106081550.014
regulation of carbohydrate metabolic processGO:0006109750.014
response to acid chemicalGO:00011011110.014
ensheathment of neuronsGO:0007272760.014
carbohydrate transportGO:0008643620.014
response to oxygen levelsGO:0070482620.014
regulation of cellular response to stressGO:00801351590.014
Fly
establishment of organelle localizationGO:00516561220.014
protein localization to organelleGO:00333651850.014
response to insulinGO:00328681000.014
peptide hormone secretionGO:00300721090.014
cellular response to lipidGO:00713961450.014
negative regulation of intracellular signal transductionGO:19025321670.014
Fly
myeloid cell differentiationGO:00300992330.014
ras protein signal transductionGO:0007265770.014
positive regulation of nervous system developmentGO:00519622210.013
negative regulation of hydrolase activityGO:0051346710.013
negative regulation of protein processingGO:0010955790.013
myelinationGO:0042552740.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
sensory perception of mechanical stimulusGO:00509541070.013
Worm
retina development in camera type eyeGO:00600411190.013
cation homeostasisGO:00550802120.013
cellular chemical homeostasisGO:00550822150.013
fat soluble vitamin biosynthetic processGO:004236240.013
methylationGO:00322591340.013
nuclear divisionGO:00002801580.013
carbohydrate biosynthetic processGO:0016051740.013
glucose transportGO:0015758560.013
polysaccharide metabolic processGO:0005976390.013
negative regulation of mapk cascadeGO:0043409650.013
Fly
digestive system developmentGO:00551232000.013
hexose transportGO:0008645560.013
peptide secretionGO:00027901140.013
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.013
positive regulation of lipid biosynthetic processGO:0046889180.013
carboxylic acid biosynthetic processGO:0046394860.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
modification dependent macromolecule catabolic processGO:00436321330.013
tissue homeostasisGO:00018941150.013
guanosine containing compound metabolic processGO:19010681440.013
regulation of protein maturationGO:1903317960.013
myosin filament assemblyGO:003103420.013
heart morphogenesisGO:00030071780.013
proteolysis involved in cellular protein catabolic processGO:00516031470.013
regulation of protein processingGO:0070613960.013
respiratory system developmentGO:00605411900.013
gtp catabolic processGO:00061841430.013
protein localization to plasma membraneGO:0072659570.013
angiogenesisGO:00015252010.013
regulation of protein localizationGO:00328802310.013
response to extracellular stimulusGO:00099911270.013
regulation of ion transmembrane transportGO:00347651190.013
nucleoside monophosphate metabolic processGO:0009123850.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.013
skin developmentGO:00435882200.012
peptidyl tyrosine modificationGO:00182121450.012
Mouse
actin mediated cell contractionGO:0070252150.012
germ cell developmentGO:00072811850.012
axon ensheathmentGO:0008366760.012
wound healingGO:00420601570.012
nucleotide biosynthetic processGO:0009165780.012
positive regulation of lipid metabolic processGO:0045834400.012
morphogenesis of embryonic epitheliumGO:00163311590.012
Mouse Fly
regulation of homeostatic processGO:00328441820.012
regulation of cellular response to growth factor stimulusGO:0090287820.012
stem cell developmentGO:00488642190.012
chromatin modificationGO:00165681870.012
energy reserve metabolic processGO:0006112390.012
engulfment of apoptotic cellGO:004365230.012
branching morphogenesis of an epithelial tubeGO:00487541590.012
Mouse
single organismal cell cell adhesionGO:00163371310.012
regulation of blood pressureGO:0008217930.012
activation of immune responseGO:00022531380.012
urogenital system developmentGO:00016552610.012
cyclic nucleotide metabolic processGO:0009187590.012
cholesterol metabolic processGO:0008203560.012
chromatin organizationGO:00063252060.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
regulation of ras protein signal transductionGO:00465781140.012
myeloid cell homeostasisGO:00022621140.012
metal ion homeostasisGO:00550651890.012
single organism cell adhesionGO:00986021560.012
guanosine containing compound catabolic processGO:19010691440.012
myosin filament organizationGO:003103330.012
meiotic cell cycle processGO:1903046770.012
regulation of lymphocyte activationGO:00512492400.012
regulation of cell substrate adhesionGO:0010810730.012
regulation of purine nucleotide catabolic processGO:00331211220.012
regulation of organ morphogenesisGO:20000271440.012
extracellular structure organizationGO:00430621480.012
defense response to other organismGO:00985421970.012
ubiquitin dependent protein catabolic processGO:00065111290.012
striated muscle myosin thick filament assemblyGO:007168810.011
multi multicellular organism processGO:00447061090.011
cell substrate junction assemblyGO:0007044240.011
Mouse
mitotic cell cycle processGO:19030471590.011
regulation of cytokine productionGO:00018172660.011
positive regulation of nucleoside metabolic processGO:0045979910.011
response to amino acidGO:0043200370.011
regulation of cell cycle processGO:00105641600.011
lipid transportGO:0006869980.011
actomyosin structure organizationGO:0031032560.011
regulation of blood vessel sizeGO:0050880560.011
skeletal muscle organ developmentGO:00605381630.011
cellular response to molecule of bacterial originGO:0071219830.011
nucleoside monophosphate catabolic processGO:0009125590.011
divalent inorganic cation transportGO:00725111780.011
glial cell differentiationGO:00100011310.011
protein ubiquitinationGO:00165671710.011
epidermis developmentGO:00085441870.011
dna metabolic processGO:00062593030.011
cardiac muscle tissue developmentGO:00487381300.011
cholesterol homeostasisGO:0042632440.011
positive regulation of proteolysisGO:0045862850.011
response to light stimulusGO:00094161350.011
organ growthGO:00352651170.011
cellular component assembly involved in morphogenesisGO:00109271390.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
activation of mapk activityGO:0000187590.011
Mouse
organelle fissionGO:00482851700.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
regulation of gtp catabolic processGO:00331241130.011
focal adhesion assemblyGO:0048041190.011
Mouse
cellular response to organic cyclic compoundGO:0071407870.011
leukocyte differentiationGO:00025213420.011
leukocyte migrationGO:00509001240.011
positive regulation of response to woundingGO:1903036660.011
positive regulation of organelle organizationGO:00106381280.011
negative regulation of fat cell differentiationGO:0045599360.011
Mouse
cellular alcohol metabolic processGO:004410730.011
stem cell differentiationGO:00488632680.011
response to nutrient levelsGO:00316671090.011
defense response to virusGO:0051607680.011
protein modification by small protein conjugation or removalGO:00706472070.011
response to drugGO:0042493750.010
regulation of transmembrane transportGO:00347621280.010
monocarboxylic acid biosynthetic processGO:0072330610.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.010
long chain fatty acid importGO:004453920.010
apoptotic signaling pathwayGO:00971903060.010
regulation of metal ion transportGO:00109591060.010
spermatid developmentGO:00072861080.010
drug catabolic processGO:004273720.010
ventricular cardiac muscle cell action potentialGO:008600540.010
intrinsic apoptotic signaling pathwayGO:00971931320.010
cellular alcohol biosynthetic processGO:004410830.010
reactive oxygen species biosynthetic processGO:190340980.010
learning or memoryGO:00076111480.010
regulation of reactive oxygen species biosynthetic processGO:190342620.010
purine nucleotide biosynthetic processGO:0006164650.010
adult behaviorGO:00305341350.010
organelle localizationGO:00516401790.010
organic hydroxy compound transportGO:0015850930.010
meiotic nuclear divisionGO:00071261150.010
glucan metabolic processGO:0044042320.010
lipid storageGO:0019915360.010
Worm
heart contractionGO:0060047930.010
Zebrafish
hematopoietic progenitor cell differentiationGO:00022441430.010

Lims2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.025
disease of anatomical entityDOID:700.025
musculoskeletal system diseaseDOID:1700.022
immune system diseaseDOID:291400.021
disease of metabolismDOID:001466700.020
central nervous system diseaseDOID:33100.018
cardiovascular system diseaseDOID:128700.015
neuropathyDOID:87000.014
neuromuscular diseaseDOID:44000.014
charcot marie tooth diseaseDOID:1059500.012
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011
neurodegenerative diseaseDOID:128900.011
vascular diseaseDOID:17800.011
inherited metabolic disorderDOID:65500.011
hematopoietic system diseaseDOID:7400.010