Mus musculus

89 known processes

Zfp423

zinc finger protein 423

(Aliases: Roaz,nur12,ataxia1,mKIAA0760,Zfp104,Znf423,Ebfaz)

Zfp423 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuroblast fate determinationGO:000740010.259
neuroblast differentiationGO:001401620.251
stem cell fate determinationGO:004886720.226
compartment pattern specificationGO:000738640.189
transmission of nerve impulseGO:0019226760.179
peripheral nervous system neuron axonogenesisGO:004893630.152
positive regulation of neuron differentiationGO:00456661410.147
regulation of cellular ketone metabolic processGO:0010565660.144
regionalizationGO:00030023370.133
anterior commissure morphogenesisGO:002196060.128
regulation of cellular amine metabolic processGO:0033238200.103
multicellular organismal signalingGO:0035637910.102
regulation of cell cycleGO:00517262810.096
neuroblast fate commitmentGO:001401710.094
forebrain developmentGO:00309003020.094
regulation of neuron differentiationGO:00456642810.092
compound eye developmentGO:004874910.087
chemotaxisGO:00069352470.085
neuronal action potentialGO:0019228540.082
kidney developmentGO:00018222130.081
embryonic epithelial tube formationGO:00018381300.081
ureteric bud developmentGO:0001657940.076
cell fate commitmentGO:00451652100.076
organ growthGO:00352651170.074
dendrite developmentGO:00163581150.073
axonogenesisGO:00074092740.069
regulation of membrane potentialGO:00423911920.067
kidney epithelium developmentGO:00720731210.066
positive regulation of cell developmentGO:00107202370.066
regulation of cellular amino acid metabolic processGO:000652150.065
amine metabolic processGO:0009308450.064
midbrain hindbrain boundary morphogenesisGO:002155540.063
limb developmentGO:00601731660.061
lymphocyte differentiationGO:00300982420.061
cellular amino acid metabolic processGO:00065201030.060
membrane organizationGO:00610242450.060
telencephalon developmentGO:00215371860.059
positive regulation of cellular amino acid metabolic processGO:004576430.058
positive regulation of cell projection organizationGO:0031346950.056
digestive tract developmentGO:00485651900.055
regulation of epithelial cell proliferationGO:00506781410.055
ensheathment of neuronsGO:0007272760.055
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.054
neuron projection guidanceGO:00974851410.053
nucleotide metabolic processGO:00091173320.052
positive regulation of cellular amine metabolic processGO:003324050.051
lateral line system developmentGO:004892510.051
defense response to other organismGO:00985421970.050
camera type eye developmentGO:00430102660.050
regulation of system processGO:00440572000.049
transmembrane transportGO:00550854120.048
morphogenesis of embryonic epitheliumGO:00163311590.046
neural tube formationGO:00018411080.045
myelinationGO:0042552740.045
muscle tissue developmentGO:00605373080.045
negative regulation of cellular amine metabolic processGO:003323910.045
oxidation reduction processGO:00551143420.044
urogenital system developmentGO:00016552610.044
mesonephros developmentGO:0001823970.044
muscle cell fate specificationGO:004269410.043
gland developmentGO:00487323300.043
synapse organizationGO:00508081250.042
positive regulation of neuron projection developmentGO:0010976790.042
digestive tract morphogenesisGO:00485461470.042
negative regulation of immune system processGO:00026832090.041
regulation of jak stat cascadeGO:0046425340.040
renal system developmentGO:00720012250.040
development of primary sexual characteristicsGO:00451371430.039
regulation of cell migrationGO:00303342190.039
ventral midline developmentGO:000741840.039
muscle cell differentiationGO:00426922610.039
primary neural tube formationGO:0014020950.038
neural tube developmentGO:00219151600.038
regulation of neuron projection developmentGO:00109751690.038
extracellular matrix organizationGO:00301981470.038
central nervous system neuron differentiationGO:00219531620.037
negative regulation of molecular functionGO:00440922580.037
pigmentationGO:0043473710.037
regulation of protein kinase activityGO:00458592320.037
neural tube closureGO:0001843900.036
striated muscle tissue developmentGO:00147062930.036
locomotory behaviorGO:00076261950.035
embryonic limb morphogenesisGO:00303261260.035
defecationGO:003042110.034
jak stat cascadeGO:0007259420.034
germ cell developmentGO:00072811850.034
organelle fissionGO:00482851700.033
cardiocyte differentiationGO:0035051870.033
actin filament organizationGO:00070151130.033
regulation of anatomical structure sizeGO:00900661780.032
appendage developmentGO:00487361660.032
positive regulation of nervous system developmentGO:00519622210.032
regulation of cellular component biogenesisGO:00440871810.031
sensory organ morphogenesisGO:00905962420.031
stem cell fate commitmentGO:004886550.031
cellular ketone metabolic processGO:0042180840.031
gliogenesisGO:00420631410.030
organic cyclic compound catabolic processGO:19013612950.030
sensory system developmentGO:004888030.030
glial cell differentiationGO:00100011310.030
mapk cascadeGO:00001652810.030
regulation of protein transportGO:00512231630.029
hindbrain developmentGO:00309021280.029
columnar cuboidal epithelial cell differentiationGO:0002065820.029
regulation of protein localizationGO:00328802310.028
axon guidanceGO:00074111410.028
action potentialGO:0001508780.028
spermatogenesisGO:00072832840.028
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742400.028
cell fate specificationGO:0001708720.028
nucleoside phosphate catabolic processGO:19012922220.028
protein polymerizationGO:0051258570.028
digestive system developmentGO:00551232000.028
ribonucleoside triphosphate metabolic processGO:00091992200.028
epithelial cell proliferationGO:00506731740.028
fat cell differentiationGO:00454441600.028
gastrulationGO:00073691160.028
macromolecule catabolic processGO:00090572810.027
positive regulation of organelle organizationGO:00106381280.027
multicellular organism growthGO:00352641610.027
fourth ventricle developmentGO:002159220.027
midgut developmentGO:000749440.027
branching morphogenesis of an epithelial tubeGO:00487541590.027
posttranscriptional regulation of gene expressionGO:00106081550.027
cell adhesionGO:00071553290.027
cytokine productionGO:00018163190.027
dorsal ventral axon guidanceGO:003356330.026
axon ensheathmentGO:0008366760.026
carbohydrate derivative catabolic processGO:19011362310.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.026
negative regulation of phosphorus metabolic processGO:00105631840.026
epithelial tube formationGO:00721751300.026
positive regulation of protein transportGO:0051222930.025
regulation of leukocyte differentiationGO:19021051590.025
stem cell differentiationGO:00488632680.025
heart trabecula morphogenesisGO:0061384260.025
adult behaviorGO:00305341350.025
heterocycle catabolic processGO:00467002800.025
maintenance of presynaptic active zone structureGO:004879010.025
establishment or maintenance of cell polarityGO:0007163860.024
cellular protein complex assemblyGO:00436231160.024
negative regulation of cell activationGO:00508661110.024
cholesterol homeostasisGO:0042632440.024
purine containing compound catabolic processGO:00725232130.024
neural tube patterningGO:0021532430.024
embryonic appendage morphogenesisGO:00351131260.024
cell type specific apoptotic processGO:00972852680.024
ion transmembrane transportGO:00342203610.024
cell cell adhesionGO:0098609410.023
regulation of mapk cascadeGO:00434082480.023
negative regulation of neuron differentiationGO:00456651010.023
purine ribonucleotide metabolic processGO:00091502900.023
protein import into nucleusGO:0006606950.023
regulation of fatty acid metabolic processGO:0019217280.023
appendage morphogenesisGO:00351071490.023
glial cell developmentGO:0021782540.023
developmental growth involved in morphogenesisGO:00605601380.023
regulation of secretionGO:00510462740.023
cardiac muscle cell differentiationGO:0055007690.022
protein catabolic processGO:00301632210.022
bone developmentGO:00603481200.022
ameboidal type cell migrationGO:00016671280.022
hematopoietic progenitor cell differentiationGO:00022441430.022
central nervous system projection neuron axonogenesisGO:0021952210.022
cellular lipid metabolic processGO:00442553230.022
lateral inhibitionGO:004633110.021
purine nucleoside catabolic processGO:00061522050.021
visceral serous pericardium developmentGO:006103220.021
homeostasis of number of cellsGO:00488722100.021
netrin activated signaling pathwayGO:003800710.021
motor neuron migrationGO:009747540.021
embryonic organ morphogenesisGO:00485622760.021
regulation of transporter activityGO:0032409570.021
muscle cell proliferationGO:0033002520.021
cardiac muscle cell proliferationGO:0060038310.021
skin developmentGO:00435882200.021
regulation of actin filament lengthGO:0030832450.021
kidney morphogenesisGO:0060993830.021
lung developmentGO:00303241640.021
formation of organ boundaryGO:001016010.020
gonad developmentGO:00084061410.020
striatal medium spiny neuron differentiationGO:002177320.020
positive regulation of protein kinase activityGO:00458601440.020
negative regulation of apoptotic signaling pathwayGO:20012341040.020
oviduct developmentGO:006006630.020
morphogenesis of a branching epitheliumGO:00611381930.020
regulation of cell projection organizationGO:00313442060.020
regulation of protein targetingGO:1903533610.019
oocyte constructionGO:000730820.019
epithelial tube morphogenesisGO:00605623030.019
male sex differentiationGO:00466611090.019
smoothened signaling pathwayGO:00072241050.019
embryonic heart tube developmentGO:0035050650.019
mitotic cell cycle processGO:19030471590.019
cell fate determinationGO:0001709320.019
regulation of secretion by cellGO:19035302490.019
mesodermal cell migrationGO:000807840.019
endocardial cushion to mesenchymal transition involved in heart valve formationGO:000319940.019
cell recognitionGO:0008037830.019
epidermal cell fate specificationGO:000995710.019
hindbrain morphogenesisGO:0021575460.019
regulation of neural retina developmentGO:006107430.019
odontogenesisGO:0042476780.019
circulatory system processGO:00030131970.019
positive regulation of purine nucleotide metabolic processGO:19005441140.019
microtubule cytoskeleton organizationGO:00002261570.019
photoreceptor cell differentiationGO:0046530520.019
negative regulation of cellular amino acid metabolic processGO:004576300.018
mesonephric epithelium developmentGO:0072163940.018
oocyte axis specificationGO:000730920.018
mesendoderm developmentGO:004838230.018
gonad morphogenesisGO:003526210.018
actin filament polymerizationGO:0030041440.018
axonal fasciculationGO:0007413150.018
purine nucleoside metabolic processGO:00422782410.018
intracellular receptor signaling pathwayGO:0030522740.018
regulation of intracellular protein transportGO:0033157820.018
nucleobase containing small molecule metabolic processGO:00550863520.018
cellular response to cytokine stimulusGO:00713451890.018
protein oligomerizationGO:0051259670.018
epithelial cell developmentGO:00020641590.018
nucleocytoplasmic transportGO:00069131390.017
cell divisionGO:00513011200.017
male gamete generationGO:00482322850.017
cell proliferation in forebrainGO:0021846300.017
neurotransmitter transportGO:0006836760.017
ribonucleoside catabolic processGO:00424542060.017
regulation of organelle organizationGO:00330432890.017
monocarboxylic acid metabolic processGO:00327871910.017
bmp signaling pathwayGO:0030509930.017
negative regulation of synapse maturationGO:200029720.017
negative regulation of cell proliferationGO:00082852960.017
single organism cell adhesionGO:00986021560.017
blood vessel morphogenesisGO:00485142850.017
regulation of mitotic cell cycleGO:00073461260.017
protein homooligomerizationGO:0051260430.017
negative regulation of phosphate metabolic processGO:00459361840.017
regulation of retina development in camera type eyeGO:190286630.017
female sex differentiationGO:0046660840.017
microtubule based processGO:00070172360.017
organelle localizationGO:00516401790.016
positive regulation of programmed cell deathGO:00430682180.016
defense response to fungusGO:0050832120.016
regulation of transcription from rna polymerase iii promoterGO:000635920.016
regulation of defense responseGO:00313472330.016
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesisGO:200076410.016
myeloid cell homeostasisGO:00022621140.016
apoptotic signaling pathwayGO:00971903060.016
purine ribonucleoside triphosphate catabolic processGO:00092071990.016
organonitrogen compound biosynthetic processGO:19015661920.016
inflammatory responseGO:00069542440.016
regulation of bmp signaling pathwayGO:0030510600.016
cellular response to dna damage stimulusGO:00069742070.016
blastocyst developmentGO:0001824800.016
peptidyl serine phosphorylationGO:0018105740.016
histone modificationGO:00165701590.016
meiotic cell cycleGO:00513211220.016
connective tissue developmentGO:00614481790.016
nuclear divisionGO:00002801580.016
cellular nitrogen compound catabolic processGO:00442702800.016
regulation of translationGO:0006417710.016
cellular response to insulin stimulusGO:0032869780.016
regulation of myelinationGO:0031641200.016
pharynx developmentGO:006046510.016
aromatic compound catabolic processGO:00194392860.016
midbrain hindbrain boundary developmentGO:003091790.016
protein modification by small protein conjugation or removalGO:00706472070.016
modification dependent protein catabolic processGO:00199411330.015
regulation of cell cycle processGO:00105641600.015
regulation of organ morphogenesisGO:20000271440.015
negative regulation of intracellular signal transductionGO:19025321670.015
regulation of intracellular transportGO:00323861590.015
neuron apoptotic processGO:00514021420.015
cellular response to peptide hormone stimulusGO:0071375920.015
negative regulation of leukocyte differentiationGO:1902106510.015
protein ubiquitinationGO:00165671710.015
negative regulation of lymphocyte activationGO:0051250910.015
establishment of protein localization to organelleGO:00725941180.015
organonitrogen compound catabolic processGO:19015652640.015
regulation of cellular catabolic processGO:00313292420.015
extracellular structure organizationGO:00430621480.015
cellular response to growth factor stimulusGO:00713631970.015
protein secretionGO:00093061110.015
response to peptideGO:19016521360.015
single organismal cell cell adhesionGO:00163371310.015
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.015
organophosphate catabolic processGO:00464342320.015
regulation of cytoskeleton organizationGO:00514931220.015
rhythmic processGO:00485111740.015
muscle system processGO:00030121410.015
renal vesicle developmentGO:0072087170.015
placenta developmentGO:00018901400.015
motor neuron axon guidanceGO:0008045260.015
formation of anatomical boundaryGO:004885960.015
nucleoside catabolic processGO:00091642060.015
pallium developmentGO:00215431200.015
neural precursor cell proliferationGO:00613511210.015
heart growthGO:0060419450.015
regulation of exit from mitosisGO:000709610.015
cardiac ventricle developmentGO:0003231830.015
actin polymerization or depolymerizationGO:0008154540.015
protein localization to organelleGO:00333651850.014
cardiac ventricle morphogenesisGO:0003208500.014
innate immune responseGO:00450871570.014
actin cytoskeleton organizationGO:00300362200.014
forelimb morphogenesisGO:0035136400.014
enucleate erythrocyte differentiationGO:004335380.014
purine ribonucleotide catabolic processGO:00091542080.014
maintenance of locationGO:0051235890.014
membrane depolarizationGO:0051899640.014
endochondral bone morphogenesisGO:0060350500.014
synaptic transmissionGO:00072683290.014
negative regulation of cell cycleGO:00457861230.014
embryonic hindlimb morphogenesisGO:0035116320.014
nucleoside phosphate metabolic processGO:00067533380.014
regulation of myeloid leukocyte differentiationGO:0002761580.014
t cell activationGO:00421102890.014
cardiac cell fate specificationGO:006091220.014
cerebellar cortex developmentGO:0021695480.014
regulation of cell activationGO:00508652890.014
circadian rhythmGO:00076231140.014
nephron epithelium developmentGO:0072009920.014
limb morphogenesisGO:00351081490.014
auditory receptor cell fate determinationGO:004266830.014
positive regulation of mapk cascadeGO:00434101700.014
carbohydrate biosynthetic processGO:0016051740.014
negative regulation of protein phosphorylationGO:00019331260.014
sterol homeostasisGO:0055092450.014
leukocyte proliferationGO:00706611720.014
mitotic cell cycleGO:00002781950.014
protein maturationGO:00516041760.014
negative regulation of t cell activationGO:0050868650.014
carbohydrate metabolic processGO:00059752300.014
cellular macromolecule catabolic processGO:00442652060.014
positive regulation of secretionGO:00510471300.014
regulation of ras protein signal transductionGO:00465781140.013
leukocyte differentiationGO:00025213420.013
regulation of cytokine productionGO:00018172660.013
ribonucleotide metabolic processGO:00092592910.013
cardiac chamber morphogenesisGO:0003206930.013
epidermis developmentGO:00085441870.013
zygotic determination of anterior posterior axis embryoGO:000735430.013
neuron migrationGO:00017641220.013
neuron fate specificationGO:0048665300.013
regulation of bindingGO:00510981110.013
negative regulation of phosphorylationGO:00423261660.013
negative regulation of gastrulationGO:200054230.013
terminal button organizationGO:007255330.013
embryonic placenta developmentGO:0001892980.013
regulation of ion transmembrane transportGO:00347651190.013
cardiac right ventricle formationGO:000321930.013
ureteric bud morphogenesisGO:0060675620.013
regulation of sequence specific dna binding transcription factor activityGO:00510901060.013
cerebellum developmentGO:0021549770.013
dna repairGO:00062811070.013
inner cell mass cell proliferationGO:0001833150.013
positive regulation of nucleotide metabolic processGO:00459811140.013
positive regulation of epithelial cell proliferationGO:0050679680.013
ventricular cardiac muscle tissue developmentGO:0003229380.013
response to organonitrogen compoundGO:00102432460.013
positive regulation of gliogenesisGO:0014015270.013
regulation of establishment of protein localizationGO:00702011810.013
regulation of circadian rhythmGO:0042752580.013
cellular response to transforming growth factor beta stimulusGO:0071560880.013
respiratory system developmentGO:00605411900.013
tube closureGO:0060606910.012
response to transforming growth factor betaGO:0071559880.012
central nervous system neuron developmentGO:0021954670.012
purine nucleoside triphosphate catabolic processGO:00091462030.012
cellular response to lipidGO:00713961450.012
multi multicellular organism processGO:00447061090.012
positive regulation of fatty acid oxidationGO:004632140.012
regulation of transferase activityGO:00513382630.012
regulation of t cell activationGO:00508631700.012
positive regulation of myeloid cell differentiationGO:0045639430.012
mrna metabolic processGO:0016071840.012
regulation of lymphocyte activationGO:00512492400.012
nephron tubule developmentGO:0072080840.012
trabecula morphogenesisGO:0061383400.012
regulation of actin polymerization or depolymerizationGO:0008064450.012
t cell differentiationGO:00302171740.012
regulation of hormone levelsGO:00108172110.012
rna processingGO:00063961050.012
dephosphorylationGO:00163111290.012
cellular response to molecule of bacterial originGO:0071219830.012
regulation of nuclear divisionGO:0051783560.012
endocardial cushion developmentGO:0003197260.012
tube formationGO:00351481400.012
telencephalon cell migrationGO:0022029550.012
cardiac muscle tissue developmentGO:00487381300.012
midbrain developmentGO:0030901350.012
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus developmentGO:006052840.012
purine containing compound metabolic processGO:00725213110.012
regulation of stem cell differentiationGO:2000736500.012
regulation of auditory receptor cell differentiationGO:004560740.012
protein modification by small protein conjugationGO:00324461870.012
central nervous system neuron axonogenesisGO:0021955280.012
regulation of cell adhesionGO:00301551540.012
positive regulation of apoptotic processGO:00430652170.012
cardiac neural crest cell migration involved in outflow tract morphogenesisGO:000325330.012
positive regulation of bindingGO:0051099490.012
organic hydroxy compound metabolic processGO:19016152030.012
morphogenesis of a branching structureGO:00017632030.012
chondrocyte developmentGO:0002063240.012
chromatin organizationGO:00063252060.011
cellular homeostasisGO:00197252400.011
cellular response to peptideGO:1901653920.011
embryonic body morphogenesisGO:0010172100.011
regulation of ossificationGO:00302781120.011
histone methylationGO:0016571710.011
negative regulation of protein metabolic processGO:00512482820.011
myeloid leukocyte migrationGO:0097529570.011
positive regulation of chromatin bindingGO:003556330.011
cellular response to hormone stimulusGO:00328701500.011
regulation of kinase activityGO:00435492490.011
developmental cell growthGO:0048588840.011
intestinal epithelial structure maintenanceGO:006072940.011
segmentationGO:0035282930.011
positive regulation of cell deathGO:00109422240.011
embryonic heart tube morphogenesisGO:0003143510.011
ribose phosphate metabolic processGO:00196932910.011
cardiac muscle tissue growthGO:0055017370.011
response to radiationGO:00093141650.011
neuromuscular processGO:0050905990.011
negative regulation of cellular protein metabolic processGO:00322692470.011
ventral spinal cord developmentGO:0021517480.011
triglyceride biosynthetic processGO:0019432170.011
regulation of fat cell differentiationGO:0045598810.011
cellular carbohydrate metabolic processGO:00442621190.011
ras protein signal transductionGO:0007265770.011
response to symbiontGO:000960820.011
glycosyl compound catabolic processGO:19016582060.011
synapse assemblyGO:0007416560.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
regulation of cytoplasmic transportGO:19036491120.011
asymmetric neuroblast divisionGO:005505910.011
regulation of g1 s transition of mitotic cell cycleGO:2000045350.011
olfactory bulb axon guidanceGO:007167810.011
response to oxidative stressGO:00069791230.011
synaptic vesicle membrane organizationGO:004849910.011
stem cell fate specificationGO:004886630.011
nuclear transportGO:00511691390.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
negative regulation of mapk cascadeGO:0043409650.011
plasma membrane fusionGO:004502690.011
retina morphogenesis in camera type eyeGO:0060042450.011
regulation of fibroblast proliferationGO:0048145340.011
spermatid developmentGO:00072861080.011
negative regulation of photoreceptor cell differentiationGO:004653340.011
metal ion homeostasisGO:00550651890.011
myelination in peripheral nervous systemGO:0022011190.010
regulation of cell motilityGO:20001452360.010
endomembrane system organizationGO:00102561470.010
translationGO:0006412930.010
prostate gland developmentGO:0030850480.010
stem cell proliferationGO:00720891170.010
mesoderm formationGO:0001707620.010
notch signaling pathwayGO:0007219710.010
skeletal system developmentGO:00015013560.010
corpus callosum morphogenesisGO:002154030.010
ribonucleoside metabolic processGO:00091192450.010
positive regulation of cell adhesionGO:0045785800.010
engulfment of apoptotic cellGO:004365230.010
regulation of cell cycle phase transitionGO:1901987770.010
regulation of ion transportGO:00432692150.010
regulation of myeloid cell differentiationGO:0045637960.010
regulation of response to woundingGO:19030341890.010
production of molecular mediator of immune responseGO:00024401030.010
spinal cord developmentGO:0021510810.010
modification dependent macromolecule catabolic processGO:00436321330.010
pancreatic pp cell differentiationGO:000331220.010
negative regulation of epithelial cell proliferationGO:0050680640.010
lymphocyte mediated immunityGO:00024491390.010
g1 s transition of mitotic cell cycleGO:0000082570.010
small gtpase mediated signal transductionGO:0007264970.010
mrna processingGO:0006397630.010
regulation of transmembrane transportGO:00347621280.010
developmental programmed cell deathGO:0010623410.010
positive regulation of extracellular matrix organizationGO:190305540.010

Zfp423 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.023
disease of anatomical entityDOID:700.023
eye and adnexa diseaseDOID:149200.023
retinal diseaseDOID:567900.023
retinal degenerationDOID:846600.023
sensory system diseaseDOID:005015500.023
eye diseaseDOID:561400.023
cancerDOID:16200.018
disease of cellular proliferationDOID:1456600.018
organ system cancerDOID:005068600.016
connective tissue diseaseDOID:6500.014
musculoskeletal system diseaseDOID:1700.014
bone diseaseDOID:008000100.014
physical disorderDOID:008001500.011