IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Srsf6

serine/arginine-rich splicing factor 6

(Aliases: AI314910,Sfrs6,AW146126,1210001E11Rik)

Ensembl: ENSMUSG00000016921
Entrez: 67996
UniProtKB: Q3TWW8

Process Predictions
Disease Predictions

Srsf6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
mrna splicing via spliceosome	GO:0000398	43	0.830	Human Fly
mrna metabolic process	GO:0016071	84	0.751	Human Fly
alternative mrna splicing via spliceosome	GO:0000380	12	0.606	Human Fly
regulation of mrna processing	GO:0050684	41	0.569	Human Fly
regulation of mrna splicing via spliceosome	GO:0048024	32	0.569	Human Fly
mrna processing	GO:0006397	63	0.492	Human Fly
negative regulation of rna splicing	GO:0033119	12	0.473	Human
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	43	0.471	Human Fly
rna splicing via transesterification reactions	GO:0000375	43	0.437	Human Fly
rna splicing	GO:0008380	54	0.408	Human Fly
rna processing	GO:0006396	105	0.390	Human Fly
regulation of rna splicing	GO:0043484	37	0.319	Human Fly
germ cell development	GO:0007281	185	0.258
negative regulation of mrna splicing via spliceosome	GO:0048025	12	0.243	Human
posttranscriptional regulation of gene expression	GO:0010608	155	0.229
negative regulation of mrna processing	GO:0050686	12	0.223	Human
regulation of mrna stability	GO:0043488	23	0.215
pole plasm assembly	GO:0007315	2	0.211
negative regulation of mrna metabolic process	GO:1903312	13	0.198	Human
regulation of alternative mrna splicing via spliceosome	GO:0000381	8	0.194	Human Fly
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	1	0.179
stem cell differentiation	GO:0048863	268	0.174
rna localization	GO:0006403	23	0.171
3 utr mediated mrna stabilization	GO:0070935	2	0.167
positive regulation of mrna metabolic process	GO:1903313	17	0.166
organelle fission	GO:0048285	170	0.163	Fly
regulation of organelle organization	GO:0033043	289	0.153
spermatogenesis	GO:0007283	284	0.146
female gamete generation	GO:0007292	74	0.145
posttranscriptional gene silencing by rna	GO:0035194	10	0.133
mitotic nuclear division	GO:0007067	48	0.132	Fly
gene silencing by rna	GO:0031047	19	0.125
regulation of mrna metabolic process	GO:1903311	43	0.125	Human Fly
heterocycle catabolic process	GO:0046700	280	0.123
development of primary sexual characteristics	GO:0045137	143	0.110
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.106
oogenesis	GO:0048477	56	0.103
cellular nitrogen compound catabolic process	GO:0044270	280	0.101
aromatic compound catabolic process	GO:0019439	286	0.096
spermatid differentiation	GO:0048515	115	0.090
developmental maturation	GO:0021700	193	0.085
intracellular mrna localization	GO:0008298	4	0.085
gonad development	GO:0008406	141	0.081
organic cyclic compound catabolic process	GO:1901361	295	0.080
male gamete generation	GO:0048232	285	0.080
stem cell development	GO:0048864	219	0.080
nuclear division	GO:0000280	158	0.079	Fly
inflammatory response	GO:0006954	244	0.072
rna 3 end processing	GO:0031123	20	0.071
nitrogen compound transport	GO:0071705	271	0.068
regulation of nuclear division	GO:0051783	56	0.068
oocyte anterior posterior axis specification	GO:0007314	2	0.067
rna interference	GO:0016246	2	0.064
nucleobase containing compound transport	GO:0015931	27	0.062
maternal placenta development	GO:0001893	20	0.062
genitalia development	GO:0048806	37	0.062
organonitrogen compound biosynthetic process	GO:1901566	192	0.061
mrna catabolic process	GO:0006402	22	0.061
response to lipopolysaccharide	GO:0032496	128	0.061
mrna stabilization	GO:0048255	9	0.060
regulation of rna stability	GO:0043487	26	0.060
rna stabilization	GO:0043489	9	0.059
positive regulation of cell death	GO:0010942	224	0.058
gene silencing	GO:0016458	38	0.057
response to molecule of bacterial origin	GO:0002237	143	0.054
development of primary female sexual characteristics	GO:0046545	73	0.053
positive regulation of mrna splicing via spliceosome	GO:0048026	11	0.052
oocyte construction	GO:0007308	2	0.051
cellular macromolecule catabolic process	GO:0044265	206	0.051
regulation of cell cycle	GO:0051726	281	0.050
intrinsic apoptotic signaling pathway	GO:0097193	132	0.050
positive regulation of translation	GO:0045727	19	0.049
dna repair	GO:0006281	107	0.048
body morphogenesis	GO:0010171	45	0.047
female sex differentiation	GO:0046660	84	0.046
chromatin modification	GO:0016568	187	0.046
cell substrate junction assembly	GO:0007044	24	0.044
amine metabolic process	GO:0009308	45	0.039
meiotic nuclear division	GO:0007126	115	0.039
microtubule cytoskeleton organization	GO:0000226	157	0.038
male meiosis	GO:0007140	37	0.038
nuclear transcribed mrna catabolic process	GO:0000956	16	0.038
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.037
positive regulation of programmed cell death	GO:0043068	218	0.037
translation	GO:0006412	93	0.037
apoptotic signaling pathway	GO:0097190	306	0.036
humoral immune response	GO:0006959	57	0.036
adult locomotory behavior	GO:0008344	91	0.036
cellular response to dna damage stimulus	GO:0006974	207	0.036
carbohydrate derivative biosynthetic process	GO:1901137	183	0.035
oxidation reduction process	GO:0055114	342	0.035
regulation of antimicrobial peptide biosynthetic process	GO:0002805	1	0.034
mitotic cell cycle	GO:0000278	195	0.033	Fly
positive regulation of intracellular estrogen receptor signaling pathway	GO:0033148	4	0.032
positive regulation of rna splicing	GO:0033120	12	0.031
regulation of cytokine production	GO:0001817	266	0.030
positive regulation of cell development	GO:0010720	237	0.030
meiotic cell cycle	GO:0051321	122	0.030
regionalization	GO:0003002	337	0.030
dna metabolic process	GO:0006259	303	0.029
stem cell maintenance	GO:0019827	130	0.029
regulation of protein complex disassembly	GO:0043244	28	0.029
maternal process involved in female pregnancy	GO:0060135	32	0.028
nucleoside metabolic process	GO:0009116	246	0.028
methylation	GO:0032259	134	0.028
myeloid leukocyte differentiation	GO:0002573	119	0.026
cell maturation	GO:0048469	127	0.026
cellular amino acid metabolic process	GO:0006520	103	0.026
oocyte differentiation	GO:0009994	35	0.025
regulation of cell cycle process	GO:0010564	160	0.025
positive regulation of apoptotic process	GO:0043065	217	0.025
regulation of cellular response to stress	GO:0080135	159	0.025
response to nutrient levels	GO:0031667	109	0.024
skeletal system development	GO:0001501	356	0.024
organic acid biosynthetic process	GO:0016053	86	0.024
mesenchyme development	GO:0060485	152	0.024
positive regulation of proteolysis	GO:0045862	85	0.024
nucleic acid transport	GO:0050657	18	0.024
compound eye development	GO:0048749	1	0.024
positive regulation of mrna processing	GO:0050685	16	0.024
regulation of cell division	GO:0051302	76	0.023
mitotic cell cycle process	GO:1903047	159	0.023	Fly
leukocyte differentiation	GO:0002521	342	0.023
protein complex disassembly	GO:0043241	40	0.023
response to extracellular stimulus	GO:0009991	127	0.023
macromolecule catabolic process	GO:0009057	281	0.022
carboxylic acid biosynthetic process	GO:0046394	86	0.022
negative regulation of cellular component organization	GO:0051129	194	0.022
antimicrobial peptide biosynthetic process	GO:0002777	2	0.021
purine ribonucleoside metabolic process	GO:0046128	241	0.021
transmembrane transport	GO:0055085	412	0.021
skin development	GO:0043588	220	0.020	Human
ribonucleoprotein complex subunit organization	GO:0071826	28	0.020	Human
purine containing compound metabolic process	GO:0072521	311	0.020
regulation of multi organism process	GO:0043900	111	0.020
regulation of cellular component biogenesis	GO:0044087	181	0.020
female gonad development	GO:0008585	71	0.019
locomotory behavior	GO:0007626	195	0.019
response to starvation	GO:0042594	65	0.019
ossification	GO:0001503	216	0.019
interspecies interaction between organisms	GO:0044419	83	0.019
antimicrobial peptide production	GO:0002775	2	0.019
cation transmembrane transport	GO:0098655	266	0.019
small molecule biosynthetic process	GO:0044283	132	0.019
regulation of apoptotic signaling pathway	GO:2001233	197	0.019
sensory perception	GO:0007600	245	0.018
cation transport	GO:0006812	399	0.018
glycosyl compound metabolic process	GO:1901657	246	0.018
regulation of cell activation	GO:0050865	289	0.018
chromatin organization	GO:0006325	206	0.018
nucleobase containing small molecule metabolic process	GO:0055086	352	0.018
regulation of cellular amine metabolic process	GO:0033238	20	0.018
cellular amine metabolic process	GO:0044106	44	0.017
respiratory tube development	GO:0030323	167	0.017	Human
cellular response to cytokine stimulus	GO:0071345	189	0.017
positive regulation of organelle organization	GO:0010638	128	0.017
multicellular organism growth	GO:0035264	161	0.017
mesenchymal cell differentiation	GO:0048762	107	0.017
segmentation	GO:0035282	93	0.017
rho protein signal transduction	GO:0007266	32	0.017
cytokine biosynthetic process	GO:0042089	68	0.016
multi multicellular organism process	GO:0044706	109	0.016
rna transport	GO:0050658	18	0.016
neuron projection extension	GO:1990138	64	0.016
microtubule based process	GO:0007017	236	0.016
positive regulation of nervous system development	GO:0051962	221	0.016
cell junction assembly	GO:0034329	52	0.016
epithelial to mesenchymal transition	GO:0001837	47	0.016
cellular homeostasis	GO:0019725	240	0.015
dna templated transcription termination	GO:0006353	4	0.015
regulation of antimicrobial humoral response	GO:0002759	3	0.015
embryonic skeletal system development	GO:0048706	120	0.015
rna catabolic process	GO:0006401	29	0.015
ion transmembrane transport	GO:0034220	361	0.015
neural retina development	GO:0003407	41	0.014
regulation of cellular amino acid metabolic process	GO:0006521	5	0.014
positive regulation of cell cycle process	GO:0090068	61	0.014
cell junction organization	GO:0034330	77	0.014
regulation of protein kinase activity	GO:0045859	232	0.014
peptidyl amino acid modification	GO:0018193	336	0.014
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.014
small gtpase mediated signal transduction	GO:0007264	97	0.014
purine containing compound biosynthetic process	GO:0072522	70	0.014
hematopoietic progenitor cell differentiation	GO:0002244	143	0.014	Mouse
epidermis development	GO:0008544	187	0.014	Human
regulation of dna templated transcription termination	GO:0031554	1	0.014
circadian rhythm	GO:0007623	114	0.014
cytokine production	GO:0001816	319	0.014
regulation of cytoskeleton organization	GO:0051493	122	0.014
camera type eye development	GO:0043010	266	0.013
macromolecular complex disassembly	GO:0032984	43	0.013
cytokine metabolic process	GO:0042107	71	0.013
exocrine system development	GO:0035272	45	0.013
regulation of ossification	GO:0030278	112	0.013
purine ribonucleotide metabolic process	GO:0009150	290	0.013
negative regulation of cell activation	GO:0050866	111	0.013
positive regulation of protein modification process	GO:0031401	299	0.013
oocyte development	GO:0048599	33	0.013
ribosomal small subunit biogenesis	GO:0042274	4	0.013
mrna 3 end processing	GO:0031124	16	0.013
posttranscriptional gene silencing	GO:0016441	10	0.013
histone methylation	GO:0016571	71	0.013
regulation of meiotic cell cycle	GO:0051445	34	0.013
positive regulation of immune effector process	GO:0002699	107	0.013
covalent chromatin modification	GO:0016569	163	0.013
receptor biosynthetic process	GO:0032800	3	0.012
cellular ketone metabolic process	GO:0042180	84	0.012
developmental growth involved in morphogenesis	GO:0060560	138	0.012
positive regulation of antimicrobial peptide biosynthetic process	GO:0002807	1	0.012
purine nucleotide metabolic process	GO:0006163	302	0.012
establishment of rna localization	GO:0051236	18	0.012
spermatid development	GO:0007286	108	0.012
regulation of cellular catabolic process	GO:0031329	242	0.012
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.012
nucleoside phosphate metabolic process	GO:0006753	338	0.012
production of molecular mediator of immune response	GO:0002440	103	0.012
organic hydroxy compound metabolic process	GO:1901615	203	0.012
negative regulation of cellular protein metabolic process	GO:0032269	247	0.012
multicellular organismal aging	GO:0010259	24	0.012
mrna transport	GO:0051028	13	0.012
protein maturation	GO:0051604	176	0.012
cell type specific apoptotic process	GO:0097285	268	0.012
cellular response to hormone stimulus	GO:0032870	150	0.012
regulation of neuron differentiation	GO:0045664	281	0.012
ribonucleoside metabolic process	GO:0009119	245	0.012
cellular chemical homeostasis	GO:0055082	215	0.011
defense response to bacterium	GO:0042742	119	0.011
cellular amino acid biosynthetic process	GO:0008652	22	0.011
regulation of spindle organization	GO:0090224	2	0.011
developmental cell growth	GO:0048588	84	0.011
regulation of protein localization	GO:0032880	231	0.011
sulfur compound biosynthetic process	GO:0044272	37	0.011
inorganic ion transmembrane transport	GO:0098660	234	0.011
regulation of cellular ketone metabolic process	GO:0010565	66	0.011
negative regulation of protein metabolic process	GO:0051248	282	0.011
b cell activation	GO:0042113	161	0.011
defense response to other organism	GO:0098542	197	0.011
antibacterial peptide production	GO:0002778	2	0.011
immune effector process	GO:0002252	321	0.011
nuclear transport	GO:0051169	139	0.011
axonogenesis	GO:0007409	274	0.011
cell division	GO:0051301	120	0.011
regulation of lymphocyte activation	GO:0051249	240	0.011
wound healing	GO:0042060	157	0.011	Human
canonical wnt signaling pathway	GO:0060070	130	0.011
establishment or maintenance of cell polarity	GO:0007163	86	0.011
sulfur compound metabolic process	GO:0006790	100	0.011
cellular response to oxidative stress	GO:0034599	76	0.011
mesenchymal cell development	GO:0014031	93	0.011
response to organic cyclic compound	GO:0014070	198	0.011
purine nucleoside metabolic process	GO:0042278	241	0.011
response to radiation	GO:0009314	165	0.011
ear development	GO:0043583	200	0.010
ribonucleoside biosynthetic process	GO:0042455	21	0.010
inorganic cation transmembrane transport	GO:0098662	207	0.010
regulation of mitotic cell cycle	GO:0007346	126	0.010
cytoplasmic transport	GO:0016482	234	0.010
circadian regulation of gene expression	GO:0032922	48	0.010
innate immune response	GO:0045087	157	0.010
regulation of transferase activity	GO:0051338	263	0.010
regulation of osteoblast differentiation	GO:0045667	67	0.010

Srsf6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.073
disease of anatomical entity	DOID:7	0.073
muscle tissue disease	DOID:66	0.073
muscular disease	DOID:0080000	0.073
myopathy	DOID:423	0.056
muscular dystrophy	DOID:9884	0.033
limb girdle muscular dystrophy	DOID:11724	0.033
nervous system disease	DOID:863	0.029
central nervous system disease	DOID:331	0.029
neurodegenerative disease	DOID:1289	0.026
motor neuron disease	DOID:231	0.026
amyotrophic lateral sclerosis	DOID:332	0.026

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network