IMP: Integrative Multi-species Prediction

Mus musculus

143 known processes

Tead2

TEA domain family member 2

(Aliases: TEF4,TEF-4,ETF,Etdf,TEAD-2)

Ensembl: ENSMUSG00000030796
Entrez: 21677
UniProtKB: P48301
UniProtKB: Q3UPV9
UniProtKB: Q80UL2

Process Predictions
Disease Predictions

Tead2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
neural tube closure	GO:0001843	90	0.887
epithelial tube morphogenesis	GO:0060562	303	0.775
neural tube development	GO:0021915	160	0.739
primary neural tube formation	GO:0014020	95	0.684
stem cell proliferation	GO:0072089	117	0.674	Fly
blood vessel morphogenesis	GO:0048514	285	0.637
positive regulation of stem cell maintenance	GO:1902459	4	0.635	Mouse
morphogenesis of embryonic epithelium	GO:0016331	159	0.630
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.597	Mouse
regulation of wnt signaling pathway	GO:0030111	123	0.555
muscle cell development	GO:0055001	133	0.542	Fly
positive regulation of cell development	GO:0010720	237	0.527	Mouse
stem cell differentiation	GO:0048863	268	0.494
wnt signaling pathway	GO:0016055	188	0.478
regulation of protein serine threonine kinase activity	GO:0071900	157	0.471	Mouse
regulation of transferase activity	GO:0051338	263	0.465	Mouse
somatic stem cell maintenance	GO:0035019	47	0.461
tube formation	GO:0035148	140	0.438
regulation of cellular ketone metabolic process	GO:0010565	66	0.416
gastrulation	GO:0007369	116	0.410
embryonic organ morphogenesis	GO:0048562	276	0.409
digestive tract development	GO:0048565	190	0.409
cell fate commitment	GO:0045165	210	0.404	Mouse
regulation of cellular component biogenesis	GO:0044087	181	0.386
positive regulation of protein kinase activity	GO:0045860	144	0.370	Mouse
regulation of protein localization	GO:0032880	231	0.365
cellular ketone metabolic process	GO:0042180	84	0.355
cellular response to lipid	GO:0071396	145	0.350
regulation of neuron differentiation	GO:0045664	281	0.343
positive regulation of kinase activity	GO:0033674	155	0.333	Mouse
cell adhesion	GO:0007155	329	0.330
regulation of cellular amino acid metabolic process	GO:0006521	5	0.329
regulation of stem cell maintenance	GO:2000036	17	0.325	Mouse
positive regulation of protein phosphorylation	GO:0001934	242	0.321	Mouse
appendage development	GO:0048736	166	0.321	Fly
regulation of cell projection organization	GO:0031344	206	0.314
cellular response to acid chemical	GO:0071229	68	0.309
trachea cartilage morphogenesis	GO:0060535	4	0.308
striated muscle tissue development	GO:0014706	293	0.304	Fly
progesterone secretion	GO:0042701	1	0.300
skeletal system morphogenesis	GO:0048705	203	0.286
regulation of hydrolase activity	GO:0051336	246	0.285
peptidyl amino acid modification	GO:0018193	336	0.285
leukocyte differentiation	GO:0002521	342	0.284
regulation of cellular amine metabolic process	GO:0033238	20	0.284
leukocyte proliferation	GO:0070661	172	0.282
t cell differentiation	GO:0030217	174	0.277
morphogenesis of a branching epithelium	GO:0061138	193	0.274
appendage morphogenesis	GO:0035107	149	0.270	Fly
muscle cell differentiation	GO:0042692	261	0.269	Fly
embryonic appendage morphogenesis	GO:0035113	126	0.265
negative regulation of catenin import into nucleus	GO:0035414	2	0.259
non canonical wnt signaling pathway	GO:0035567	33	0.259
nephron epithelium development	GO:0072009	92	0.255
cellular amino acid metabolic process	GO:0006520	103	0.252
paraxial mesoderm development	GO:0048339	18	0.248
cellular amine metabolic process	GO:0044106	44	0.248
cell junction organization	GO:0034330	77	0.247
retinal blood vessel morphogenesis	GO:0061304	3	0.244
epithelial tube formation	GO:0072175	130	0.237
lymphocyte differentiation	GO:0030098	242	0.235
positive regulation of nervous system development	GO:0051962	221	0.223
regulation of epithelial to mesenchymal transition	GO:0010717	22	0.223
lipid localization	GO:0010876	126	0.222
protein localization to nucleus	GO:0034504	121	0.221
limb development	GO:0060173	166	0.221
establishment of planar polarity involved in neural tube closure	GO:0090177	15	0.220
regulation of bmp signaling pathway	GO:0030510	60	0.215
positive regulation of cell death	GO:0010942	224	0.213
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.212
morphogenesis of a polarized epithelium	GO:0001738	37	0.210
stem cell maintenance	GO:0019827	130	0.208	Mouse
regulation of cell activation	GO:0050865	289	0.206
positive regulation of glial cell proliferation	GO:0060252	4	0.206
t cell activation	GO:0042110	289	0.205
heart morphogenesis	GO:0003007	178	0.205
regulation of rho gtpase activity	GO:0032319	58	0.204
muscular septum morphogenesis	GO:0003150	4	0.202
lung development	GO:0030324	164	0.202
ossification	GO:0001503	216	0.200
gtp catabolic process	GO:0006184	143	0.198
regulation of hippo signaling	GO:0035330	1	0.197	Fly
synapse assembly	GO:0007416	56	0.195
wnt signaling pathway planar cell polarity pathway	GO:0060071	27	0.192
neural tube formation	GO:0001841	108	0.190
amine metabolic process	GO:0009308	45	0.190
mesoderm development	GO:0007498	100	0.189
actin cytoskeleton organization	GO:0030036	220	0.187
negative regulation of bmp signaling pathway	GO:0030514	35	0.187
cerebellum vasculature development	GO:0061300	1	0.187
nephron development	GO:0072006	109	0.184
cartilage development	GO:0051216	140	0.182
cell fate specification	GO:0001708	72	0.181	Mouse
positive regulation of mapk cascade	GO:0043410	170	0.181
regulation of establishment of planar polarity	GO:0090175	28	0.180
establishment of tissue polarity	GO:0007164	28	0.175
embryonic limb morphogenesis	GO:0030326	126	0.174
regulation of establishment of protein localization	GO:0070201	181	0.172
canonical wnt signaling pathway	GO:0060070	130	0.171
negative regulation of execution phase of apoptosis	GO:1900118	4	0.171
neural precursor cell proliferation	GO:0061351	121	0.171
negative regulation of hepatocyte differentiation	GO:0070367	1	0.171
embryonic heart tube development	GO:0035050	65	0.170
gonad development	GO:0008406	141	0.169
ras protein signal transduction	GO:0007265	77	0.169
lymphocyte proliferation	GO:0046651	164	0.167
cilium morphogenesis	GO:0060271	102	0.166
embryonic nail plate morphogenesis	GO:0035880	3	0.165
development of primary sexual characteristics	GO:0045137	143	0.163
positive regulation of programmed cell death	GO:0043068	218	0.161
establishment of planar polarity	GO:0001736	28	0.159
stem cell division	GO:0017145	30	0.159
positive regulation of protein modification process	GO:0031401	299	0.154	Mouse
camera type eye development	GO:0043010	266	0.154
skeletal muscle organ development	GO:0060538	163	0.153
negative regulation of phosphorus metabolic process	GO:0010563	184	0.153
regulation of kinase activity	GO:0043549	249	0.152	Mouse
nucleocytoplasmic transport	GO:0006913	139	0.152
syncytiotrophoblast cell differentiation involved in labyrinthine layer development	GO:0060715	2	0.151
b cell activation	GO:0042113	161	0.150
cytoplasmic transport	GO:0016482	234	0.150
morphogenesis of a branching structure	GO:0001763	203	0.147
negative regulation of wnt signaling pathway	GO:0030178	73	0.146
regulation of chorionic trophoblast cell proliferation	GO:1901382	1	0.146
hippo signaling	GO:0035329	11	0.145	Mouse Fly
renal tubule development	GO:0061326	87	0.144
protein modification by small protein conjugation or removal	GO:0070647	207	0.144
mesoderm formation	GO:0001707	62	0.144
planar cell polarity pathway involved in outflow tract morphogenesis	GO:0061347	2	0.142
regulation of protein transport	GO:0051223	163	0.140
regulation of lymphocyte proliferation	GO:0050670	117	0.140
tube closure	GO:0060606	91	0.136
multi multicellular organism process	GO:0044706	109	0.136	Mouse
embryonic digit morphogenesis	GO:0042733	56	0.135
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	GO:0014834	3	0.134
regulation of protein kinase activity	GO:0045859	232	0.133	Mouse
protein import into nucleus	GO:0006606	95	0.133
limb morphogenesis	GO:0035108	149	0.132
regulation of stem cell differentiation	GO:2000736	50	0.131
negative regulation of immune system process	GO:0002683	209	0.131
non canonical wnt signaling pathway involved in heart development	GO:0061341	3	0.131
regulation of ras gtpase activity	GO:0032318	88	0.130
sensory organ morphogenesis	GO:0090596	242	0.128	Fly
central nervous system neuron differentiation	GO:0021953	162	0.127
regulation of canonical wnt signaling pathway	GO:0060828	82	0.126
ear morphogenesis	GO:0042471	118	0.126
single organism cell adhesion	GO:0098602	156	0.125
gtp metabolic process	GO:0046039	144	0.123
regulation of fat cell differentiation	GO:0045598	81	0.122
mesenchymal cell differentiation	GO:0048762	107	0.122
negative regulation of protein modification process	GO:0031400	163	0.122
regulation of cell migration	GO:0030334	219	0.121
planar cell polarity pathway involved in neural tube closure	GO:0090179	14	0.121
positive regulation of organelle organization	GO:0010638	128	0.121
hematopoietic stem cell proliferation	GO:0071425	13	0.120
regulation of neuron projection development	GO:0010975	169	0.119
cellular response to retinoic acid	GO:0071300	25	0.119
response to acid chemical	GO:0001101	111	0.116
regulation of establishment of planar polarity involved in neural tube closure	GO:0090178	15	0.116
positive regulation of apoptotic process	GO:0043065	217	0.116
regulation of apoptotic signaling pathway	GO:2001233	197	0.116
regulation of cell motility	GO:2000145	236	0.115
regulation of protein targeting	GO:1903533	61	0.114
epithelial cell proliferation	GO:0050673	174	0.114
protein import	GO:0017038	101	0.113
stem cell development	GO:0048864	219	0.113	Mouse
nuclear import	GO:0051170	95	0.113
mesoderm morphogenesis	GO:0048332	64	0.112
regulation of cellular response to stress	GO:0080135	159	0.112
negative regulation of synapse assembly	GO:0051964	3	0.112
renal system development	GO:0072001	225	0.110
positive regulation of cellular amine metabolic process	GO:0033240	5	0.109
negative regulation of mitotic cell cycle embryonic	GO:0045976	2	0.109
positive regulation of cell activation	GO:0050867	158	0.108
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.108
establishment of planar polarity of embryonic epithelium	GO:0042249	16	0.107
cerebellum vasculature morphogenesis	GO:0061301	1	0.106
notochord development	GO:0030903	20	0.106
striated muscle cell development	GO:0055002	125	0.106	Fly
myeloid leukocyte differentiation	GO:0002573	119	0.106
regulation of organ morphogenesis	GO:2000027	144	0.105
embryonic heart tube morphogenesis	GO:0003143	51	0.105
kidney morphogenesis	GO:0060993	83	0.104
regulation of gliogenesis	GO:0014013	50	0.104
negative regulation of fat cell differentiation	GO:0045599	36	0.103
asymmetric neuroblast division	GO:0055059	1	0.103
labyrinthine layer blood vessel development	GO:0060716	21	0.103
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.103
maintenance of location	GO:0051235	89	0.103
cardiac right atrium morphogenesis	GO:0003213	3	0.102
negative regulation of cell development	GO:0010721	169	0.101
steroid metabolic process	GO:0008202	119	0.101
gliogenesis	GO:0042063	141	0.100
bmp signaling pathway	GO:0030509	93	0.099
negative regulation of molecular function	GO:0044092	258	0.099
planar cell polarity pathway involved in ventricular septum morphogenesis	GO:0061348	2	0.099
peptidyl tyrosine modification	GO:0018212	145	0.099
cilium assembly	GO:0042384	81	0.099
lipid biosynthetic process	GO:0008610	179	0.099
renal vesicle induction	GO:0072034	3	0.098
muscle tissue development	GO:0060537	308	0.098	Fly
nephron tubule morphogenesis	GO:0072078	68	0.098
regulation of cytoplasmic transport	GO:1903649	112	0.097
cytokine production	GO:0001816	319	0.097
nucleoside triphosphate metabolic process	GO:0009141	230	0.097
digestive tract morphogenesis	GO:0048546	147	0.097
apoptotic signaling pathway	GO:0097190	306	0.096
cell cell junction organization	GO:0045216	72	0.096
development of primary male sexual characteristics	GO:0046546	88	0.096
nucleoside triphosphate catabolic process	GO:0009143	205	0.095
positive regulation of map kinase activity	GO:0043406	84	0.095
regulation of epithelial cell proliferation	GO:0050678	141	0.095
positive regulation of secretion by cell	GO:1903532	114	0.095
fat cell differentiation	GO:0045444	160	0.095
nucleoside catabolic process	GO:0009164	206	0.095
regulation of t cell activation	GO:0050863	170	0.094
purine ribonucleoside catabolic process	GO:0046130	205	0.094
regulation of map kinase activity	GO:0043405	120	0.094
wnt signaling pathway involved in forebrain neuroblast division	GO:0021874	2	0.093
embryonic epithelial tube formation	GO:0001838	130	0.093
cardiac septum morphogenesis	GO:0060411	46	0.093
respiratory system development	GO:0060541	190	0.092
protein targeting	GO:0006605	143	0.091
maintenance of cell number	GO:0098727	3	0.091
purine nucleoside metabolic process	GO:0042278	241	0.090
mesenchyme development	GO:0060485	152	0.090
positive regulation of stem cell proliferation	GO:2000648	59	0.090
negative regulation of protein metabolic process	GO:0051248	282	0.090
cellular lipid metabolic process	GO:0044255	323	0.089
endocytosis	GO:0006897	168	0.089
regulation of kidney development	GO:0090183	40	0.088
ribonucleotide metabolic process	GO:0009259	291	0.088
neuroblast differentiation	GO:0014016	2	0.088
intracellular protein transport	GO:0006886	204	0.088
lens morphogenesis in camera type eye	GO:0002089	24	0.088
peptidyl tyrosine phosphorylation	GO:0018108	143	0.087
respiratory tube development	GO:0030323	167	0.086
purine ribonucleotide catabolic process	GO:0009154	208	0.086
central nervous system vasculogenesis	GO:0022009	3	0.085
blastocyst development	GO:0001824	80	0.085	Mouse
positive regulation of stem cell differentiation	GO:2000738	23	0.085	Mouse
regulation of nucleocytoplasmic transport	GO:0046822	73	0.085
establishment or maintenance of cell polarity	GO:0007163	86	0.085
organic hydroxy compound metabolic process	GO:1901615	203	0.084
macromolecule catabolic process	GO:0009057	281	0.084
wound healing	GO:0042060	157	0.084
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.084
regulation of cell cycle	GO:0051726	281	0.084
substrate adhesion dependent cell spreading	GO:0034446	30	0.084
somitogenesis	GO:0001756	69	0.084
angiogenesis	GO:0001525	201	0.083
myeloid cell differentiation	GO:0030099	233	0.083
actin filament organization	GO:0007015	113	0.083
regulation of stem cell proliferation	GO:0072091	78	0.082
regulation of intracellular transport	GO:0032386	159	0.082
regulation of leukocyte proliferation	GO:0070663	121	0.081
aromatic compound catabolic process	GO:0019439	286	0.081
regulation of cell projection assembly	GO:0060491	38	0.081
cell substrate adhesion	GO:0031589	130	0.080
chorionic trophoblast cell proliferation	GO:0097360	1	0.080
lipid transport	GO:0006869	98	0.080
regulation of tight junction assembly	GO:2000810	2	0.080
regulation of gtp catabolic process	GO:0033124	113	0.080
regulation of cell adhesion	GO:0030155	154	0.080
single organism nuclear import	GO:1902593	95	0.080
positive regulation of protein transport	GO:0051222	93	0.079
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.079
regulation of neuron apoptotic process	GO:0043523	122	0.079
protein localization to organelle	GO:0033365	185	0.078
oviduct development	GO:0060066	3	0.078
regulation of myeloid cell differentiation	GO:0045637	96	0.078
planar cell polarity pathway involved in pericardium morphogenesis	GO:0061354	2	0.076
regionalization	GO:0003002	337	0.076
organophosphate catabolic process	GO:0046434	232	0.076
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.076
regulation of muscle tissue development	GO:1901861	97	0.076
embryonic placenta development	GO:0001892	98	0.076
biomineral tissue development	GO:0031214	64	0.076
labyrinthine layer development	GO:0060711	49	0.076
establishment of organ orientation	GO:0048561	1	0.075
rac protein signal transduction	GO:0016601	13	0.075
regulation of actin filament bundle assembly	GO:0032231	18	0.074
mammary gland epithelium development	GO:0061180	65	0.074
regulation of protein import into nucleus	GO:0042306	52	0.074
ubiquitin dependent protein catabolic process	GO:0006511	129	0.074
guanosine containing compound metabolic process	GO:1901068	144	0.073
positive regulation of protein secretion	GO:0050714	52	0.073
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.073
regulation of secretion	GO:0051046	274	0.073
response to retinoic acid	GO:0032526	56	0.073
regulation of jun kinase activity	GO:0043506	40	0.072
apical junction assembly	GO:0043297	15	0.072
cardiac septum development	GO:0003279	59	0.071
negative regulation of cell proliferation	GO:0008285	296	0.070
developmental maturation	GO:0021700	193	0.070
cell division	GO:0051301	120	0.070
endocardial cushion to mesenchymal transition involved in heart valve formation	GO:0003199	4	0.069
catenin import into nucleus	GO:0035411	6	0.069
carbohydrate derivative catabolic process	GO:1901136	231	0.068
neuroblast proliferation	GO:0007405	49	0.068
homeostasis of number of cells	GO:0048872	210	0.068
nucleoside metabolic process	GO:0009116	246	0.068
mesonephric duct morphogenesis	GO:0072180	4	0.068
regulation of cell cycle process	GO:0010564	160	0.068
regulation of cell substrate adhesion	GO:0010810	73	0.068
sensory perception of chemical stimulus	GO:0007606	51	0.068
epithelial cell development	GO:0002064	159	0.068
organelle fission	GO:0048285	170	0.067
response to organic cyclic compound	GO:0014070	198	0.067
positive regulation of interleukin 8 secretion	GO:2000484	1	0.067
positive regulation of lymphocyte proliferation	GO:0050671	70	0.067
regulation of nucleoside metabolic process	GO:0009118	130	0.067
regulation of neural precursor cell proliferation	GO:2000177	70	0.067
alpha beta t cell differentiation	GO:0046632	69	0.067
axis elongation involved in somitogenesis	GO:0090245	4	0.066
mitotic cell cycle	GO:0000278	195	0.066
nephron tubule development	GO:0072080	84	0.065
morphogenesis of an epithelial sheet	GO:0002011	27	0.065
bone mineralization	GO:0030282	54	0.065
positive regulation of cellular catabolic process	GO:0031331	148	0.064
ribonucleoside catabolic process	GO:0042454	206	0.064
organ growth	GO:0035265	117	0.064
positive regulation of transferase activity	GO:0051347	167	0.064	Mouse
rho protein signal transduction	GO:0007266	32	0.064
positive regulation of canonical wnt signaling pathway	GO:0090263	29	0.063
lateral mesoderm development	GO:0048368	13	0.063
regulation of b cell proliferation	GO:0030888	39	0.063
gland development	GO:0048732	330	0.063
regulation of actin cytoskeleton organization	GO:0032956	84	0.063
establishment of planar polarity involved in nephron morphogenesis	GO:0072046	1	0.063
epithelial cell morphogenesis	GO:0003382	41	0.063
metanephric nephron epithelium development	GO:0072243	19	0.063
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.063
cell proliferation in forebrain	GO:0021846	30	0.063
tissue regeneration	GO:0042246	22	0.063
cellular chemical homeostasis	GO:0055082	215	0.063
regulation of lymphocyte differentiation	GO:0045619	107	0.062
placenta development	GO:0001890	140	0.062
lens development in camera type eye	GO:0002088	62	0.062
regulation of intracellular protein transport	GO:0033157	82	0.062
ventricular septum morphogenesis	GO:0060412	27	0.062
synapse organization	GO:0050808	125	0.062
actin filament bundle assembly	GO:0051017	40	0.061
positive regulation of neuron differentiation	GO:0045666	141	0.061
metanephric tubule development	GO:0072170	18	0.061
ameboidal type cell migration	GO:0001667	128	0.061
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.061
cellular protein catabolic process	GO:0044257	155	0.061
glycosyl compound catabolic process	GO:1901658	206	0.060
regulation of organelle organization	GO:0033043	289	0.060
branching morphogenesis of an epithelial tube	GO:0048754	159	0.060
negative regulation of neuron differentiation	GO:0045665	101	0.060
blastocyst formation	GO:0001825	33	0.060	Mouse
negative regulation of leukocyte differentiation	GO:1902106	51	0.060
forebrain radial glial cell differentiation	GO:0021861	4	0.060
regulation of hormone levels	GO:0010817	211	0.060
neuron projection guidance	GO:0097485	141	0.059
meiotic nuclear division	GO:0007126	115	0.059
thymus development	GO:0048538	41	0.059
regulation of nucleotide catabolic process	GO:0030811	122	0.058
chemotaxis	GO:0006935	247	0.058
positive regulation of secondary heart field cardioblast proliferation	GO:0072513	4	0.058
lamellipodium organization	GO:0097581	29	0.058
convergent extension	GO:0060026	14	0.058
kidney epithelium development	GO:0072073	121	0.058
synaptic transmission	GO:0007268	329	0.058
glial cell differentiation	GO:0010001	131	0.058
neural tube patterning	GO:0021532	43	0.058
wnt signaling pathway involved in somitogenesis	GO:0090244	4	0.057
regulation of ossification	GO:0030278	112	0.057
protein ubiquitination	GO:0016567	171	0.057
formation of primary germ layer	GO:0001704	77	0.057
t cell differentiation in thymus	GO:0033077	77	0.057
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.057
regulation of protein localization to nucleus	GO:1900180	60	0.057
fasciculation of sensory neuron axon	GO:0097155	3	0.057
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.057
response to fibroblast growth factor	GO:0071774	47	0.056
canonical wnt signaling pathway involved in regulation of cell proliferation	GO:0044340	3	0.056
nitrogen compound transport	GO:0071705	271	0.056
positive regulation of jnk cascade	GO:0046330	46	0.056
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.056
planar cell polarity pathway involved in heart morphogenesis	GO:0061346	3	0.056
urogenital system development	GO:0001655	261	0.055
regulation of t cell differentiation	GO:0045580	83	0.055
adherens junction assembly	GO:0034333	22	0.055
b cell proliferation	GO:0042100	53	0.055
regulation of jnk cascade	GO:0046328	62	0.055
negative regulation of intracellular signal transduction	GO:1902532	167	0.055	Fly
negative regulation of protein phosphorylation	GO:0001933	126	0.055
embryonic camera type eye development	GO:0031076	36	0.054
notochord formation	GO:0014028	5	0.054
production of molecular mediator of immune response	GO:0002440	103	0.054
somite development	GO:0061053	81	0.054
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation	GO:0044343	1	0.054
small gtpase mediated signal transduction	GO:0007264	97	0.054
skeletal muscle tissue regeneration	GO:0043403	20	0.054
cardiocyte differentiation	GO:0035051	87	0.054	Fly
purine ribonucleotide metabolic process	GO:0009150	290	0.053
renal tubule morphogenesis	GO:0061333	72	0.053
endocrine system development	GO:0035270	98	0.053
organic anion transport	GO:0015711	137	0.053
response to organonitrogen compound	GO:0010243	246	0.053
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000079	1	0.053
negative regulation of phosphate metabolic process	GO:0045936	184	0.052
astrocyte differentiation	GO:0048708	43	0.052
bone development	GO:0060348	120	0.052
negative regulation of nervous system development	GO:0051961	156	0.052
protein catabolic process	GO:0030163	221	0.051
fasciculation of motor neuron axon	GO:0097156	2	0.051
germ cell development	GO:0007281	185	0.051	Fly
hippocampus development	GO:0021766	52	0.051
nephron epithelium morphogenesis	GO:0072088	68	0.051
regulation of asymmetric cell division	GO:0009786	4	0.051
nucleobase containing small molecule metabolic process	GO:0055086	352	0.051
glycerolipid metabolic process	GO:0046486	122	0.051
negative regulation of kinase activity	GO:0033673	81	0.050
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.050
skeletal muscle cell differentiation	GO:0035914	66	0.050
ear development	GO:0043583	200	0.050
jnk cascade	GO:0007254	72	0.050
protein modification by small protein conjugation	GO:0032446	187	0.050
negative regulation of neuron projection regeneration	GO:0070571	3	0.050
heart formation	GO:0060914	16	0.050
cell cell signaling involved in cell fate commitment	GO:0045168	35	0.050
kidney rudiment formation	GO:0072003	3	0.050
antimicrobial peptide production	GO:0002775	2	0.049
axon guidance	GO:0007411	141	0.049
cardiac cell development	GO:0055006	41	0.049	Fly
non canonical wnt signaling pathway via jnk cascade	GO:0038031	3	0.049
negative regulation of stem cell differentiation	GO:2000737	14	0.049
ribonucleoside metabolic process	GO:0009119	245	0.049
positive regulation of cell migration	GO:0030335	109	0.049
regulation of mapk cascade	GO:0043408	248	0.049
mesodermal cell migration	GO:0008078	4	0.049
dna metabolic process	GO:0006259	303	0.049
cranial nerve morphogenesis	GO:0021602	26	0.049
cell type specific apoptotic process	GO:0097285	268	0.048
purine nucleotide catabolic process	GO:0006195	211	0.048
positive regulation of t cell activation	GO:0050870	101	0.048
regulation of actin filament based process	GO:0032970	99	0.048
cellular nitrogen compound catabolic process	GO:0044270	280	0.048
guanosine containing compound catabolic process	GO:1901069	144	0.048
positive regulation of muscle tissue development	GO:1901863	32	0.048
placenta blood vessel development	GO:0060674	31	0.047
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.047
epidermis development	GO:0008544	187	0.047
male gonad development	GO:0008584	88	0.047
body morphogenesis	GO:0010171	45	0.047
regulation of muscle system process	GO:0090257	80	0.047	Mouse
skin development	GO:0043588	220	0.047
meiotic cell cycle	GO:0051321	122	0.047
endodermal cell fate specification	GO:0001714	4	0.046
regulation of cellular catabolic process	GO:0031329	242	0.046
cytokine secretion	GO:0050663	72	0.046
positive regulation of gtpase activity	GO:0043547	85	0.046
skeletal system development	GO:0001501	356	0.046
muscle system process	GO:0003012	141	0.046	Mouse
myoblast differentiation involved in skeletal muscle regeneration	GO:0014835	3	0.046
hypophysis morphogenesis	GO:0048850	3	0.046
regulation of osteoblast differentiation	GO:0045667	67	0.046
mitral valve development	GO:0003174	4	0.046
kidney development	GO:0001822	213	0.046
nuclear transport	GO:0051169	139	0.046
endocrine process	GO:0050886	39	0.045
positive regulation of leukocyte differentiation	GO:1902107	86	0.045
actomyosin structure organization	GO:0031032	56	0.045
negative regulation of cellular protein metabolic process	GO:0032269	247	0.045
muscle adaptation	GO:0043500	39	0.045	Mouse
negative regulation of gastrulation	GO:2000542	3	0.045
stress activated mapk cascade	GO:0051403	80	0.045
positive regulation of gliogenesis	GO:0014015	27	0.045
positive regulation of stress activated mapk cascade	GO:0032874	48	0.045
positive regulation of wnt signaling pathway	GO:0030177	45	0.045
axis elongation	GO:0003401	30	0.044
axonogenesis	GO:0007409	274	0.044
metanephric nephron tubule development	GO:0072234	16	0.044
regulation of anagen	GO:0051884	1	0.044
glucose homeostasis	GO:0042593	128	0.044
positive regulation of cell cell adhesion mediated by cadherin	GO:2000049	2	0.044
telencephalon development	GO:0021537	186	0.044
mesenchymal cell development	GO:0014031	93	0.044
regulation of cytoskeleton organization	GO:0051493	122	0.044
extrinsic apoptotic signaling pathway	GO:0097191	126	0.044
regulation of secretion by cell	GO:1903530	249	0.043
nuclear division	GO:0000280	158	0.043
cell cell adhesion	GO:0098609	41	0.043
adaptive immune response	GO:0002250	155	0.043
digestive system development	GO:0055123	200	0.042
mesonephric tubule morphogenesis	GO:0072171	63	0.042
positive regulation of long term neuronal synaptic plasticity	GO:0048170	3	0.042
negative regulation of canonical wnt signaling pathway	GO:0090090	51	0.042
mesonephric tubule development	GO:0072164	94	0.042
positive regulation of mesenchymal cell proliferation	GO:0002053	33	0.042
formation of radial glial scaffolds	GO:0021943	4	0.042
hindbrain formation	GO:0021576	1	0.042
nerve development	GO:0021675	67	0.042
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.042
artery development	GO:0060840	53	0.042
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.042

Tead2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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