IMP: Integrative Multi-species Prediction

Mus musculus

75 known processes

Catsper1

cation channel, sperm associated 1

(Aliases: KSper,Catsper)

Ensembl: ENSMUSG00000038498
Entrez: 225865
UniProtKB: Q91ZR5

Process Predictions
Disease Predictions

Catsper1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
spermatid differentiation	GO:0048515	115	0.451
spermatid development	GO:0007286	108	0.392
transmembrane transport	GO:0055085	412	0.239
spermatogenesis	GO:0007283	284	0.230
calcium ion transport	GO:0006816	159	0.210
inorganic ion transmembrane transport	GO:0098660	234	0.205
male gamete generation	GO:0048232	285	0.201
cell cell recognition	GO:0009988	44	0.199
germ cell development	GO:0007281	185	0.183
activation of immune response	GO:0002253	138	0.170
ion transmembrane transport	GO:0034220	361	0.165
regulation of ion transport	GO:0043269	215	0.152
inorganic cation transmembrane transport	GO:0098662	207	0.127
divalent metal ion transport	GO:0070838	172	0.122
sperm capacitation	GO:0048240	17	0.121
cell recognition	GO:0008037	83	0.119
regulation of ion transmembrane transport	GO:0034765	119	0.119
cation transmembrane transport	GO:0098655	266	0.113
regulation of transmembrane transport	GO:0034762	128	0.102
binding of sperm to zona pellucida	GO:0007339	34	0.101
locomotory behavior	GO:0007626	195	0.098
immune response activating signal transduction	GO:0002757	116	0.083
immune response regulating signaling pathway	GO:0002764	125	0.081
microtubule based process	GO:0007017	236	0.080
sperm motility	GO:0030317	47	0.079
lymphocyte differentiation	GO:0030098	242	0.070
leukocyte differentiation	GO:0002521	342	0.063
cytokine production	GO:0001816	319	0.054
hematopoietic progenitor cell differentiation	GO:0002244	143	0.050
positive regulation of innate immune response	GO:0045089	80	0.049
regionalization	GO:0003002	337	0.048
asymmetric neuroblast division	GO:0055059	1	0.048
cation transport	GO:0006812	399	0.047
homeostasis of number of cells	GO:0048872	210	0.046
regulation of secretion	GO:0051046	274	0.045
single fertilization	GO:0007338	82	0.043
sperm egg recognition	GO:0035036	37	0.042
positive regulation of leukocyte differentiation	GO:1902107	86	0.041
regulation of system process	GO:0044057	200	0.039
forebrain development	GO:0030900	302	0.034
positive regulation of ion transport	GO:0043270	65	0.034
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.034
negative regulation of immune system process	GO:0002683	209	0.033
epithelial cell proliferation	GO:0050673	174	0.032
wound healing	GO:0042060	157	0.031
cellular response to hormone stimulus	GO:0032870	150	0.031
regulation of cell motility	GO:2000145	236	0.031
regulation of transferase activity	GO:0051338	263	0.031
spleen development	GO:0048536	39	0.030
regulation of leukocyte differentiation	GO:1902105	159	0.030
developmental maturation	GO:0021700	193	0.030
spinal cord oligodendrocyte cell fate specification	GO:0021530	3	0.029
multicellular organismal signaling	GO:0035637	91	0.029
regulation of metal ion transport	GO:0010959	106	0.028
inflammatory response	GO:0006954	244	0.028
t cell activation	GO:0042110	289	0.028
b cell activation	GO:0042113	161	0.028
regulation of white fat cell proliferation	GO:0070350	2	0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.027
male genitalia morphogenesis	GO:0048808	4	0.027
action potential	GO:0001508	78	0.027
adult locomotory behavior	GO:0008344	91	0.026
myeloid cell differentiation	GO:0030099	233	0.026
regulation of cytokine production	GO:0001817	266	0.026
fertilization	GO:0009566	127	0.026
t cell differentiation in thymus	GO:0033077	77	0.026
phospholipid metabolic process	GO:0006644	87	0.026
protein catabolic process	GO:0030163	221	0.025
positive regulation of cell activation	GO:0050867	158	0.024
blood circulation	GO:0008015	195	0.024
dephosphorylation	GO:0016311	129	0.024
regulation of cell activation	GO:0050865	289	0.023
skin development	GO:0043588	220	0.023
cellular response to lipid	GO:0071396	145	0.023
organelle localization	GO:0051640	179	0.023
t cell differentiation	GO:0030217	174	0.023
divalent inorganic cation transport	GO:0072511	178	0.023
cognition	GO:0050890	149	0.023
positive regulation of vasoconstriction	GO:0045907	4	0.023
response to steroid hormone	GO:0048545	56	0.022
regulation of neuron differentiation	GO:0045664	281	0.022
regulation of innate immune response	GO:0045088	91	0.022
macromolecule catabolic process	GO:0009057	281	0.022
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090100	43	0.022
calcium ion homeostasis	GO:0055074	127	0.022
mitotic cell cycle	GO:0000278	195	0.022
protein localization to organelle	GO:0033365	185	0.022
regulation of lymphocyte activation	GO:0051249	240	0.022
regulation of erk1 and erk2 cascade	GO:0070372	71	0.022
regulation of cell migration	GO:0030334	219	0.022
myeloid leukocyte differentiation	GO:0002573	119	0.021
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.021
endomembrane system organization	GO:0010256	147	0.021
regulation of cell adhesion	GO:0030155	154	0.021
mapk cascade	GO:0000165	281	0.021
blood vessel morphogenesis	GO:0048514	285	0.021
positive regulation of lymphocyte activation	GO:0051251	140	0.021
ensheathment of neurons	GO:0007272	76	0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.020
regulation of lipid metabolic process	GO:0019216	118	0.020
negative regulation of cellular component organization	GO:0051129	194	0.020
cellular response to growth factor stimulus	GO:0071363	197	0.020
positive regulation of cytokine production	GO:0001819	174	0.020
cell maturation	GO:0048469	127	0.020
positive regulation of defense response	GO:0031349	124	0.020
leukocyte activation involved in immune response	GO:0002366	126	0.020
regulation of response to wounding	GO:1903034	189	0.020
wnt signaling pathway	GO:0016055	188	0.020
lung cell differentiation	GO:0060479	30	0.020
circulatory system process	GO:0003013	197	0.020
regulation of mitotic cell cycle	GO:0007346	126	0.019
regulation of voltage gated calcium channel activity	GO:1901385	4	0.019
regulation of cellular ketone metabolic process	GO:0010565	66	0.019
heart morphogenesis	GO:0003007	178	0.019
somatic sex determination	GO:0018993	2	0.019
meiotic cell cycle	GO:0051321	122	0.019
regulation of cellular component biogenesis	GO:0044087	181	0.019
regulation of kinase activity	GO:0043549	249	0.019
regulation of protein complex assembly	GO:0043254	83	0.019
prevention of polyspermy	GO:0060468	4	0.019
positive regulation of kinase activity	GO:0033674	155	0.018
immune response activating cell surface receptor signaling pathway	GO:0002429	72	0.018
negative regulation of phosphorylation	GO:0042326	166	0.018
cytoplasmic transport	GO:0016482	234	0.018
heart contraction	GO:0060047	93	0.018
membrane organization	GO:0061024	245	0.018
mitotic cell cycle process	GO:1903047	159	0.018
chromatin organization	GO:0006325	206	0.017
cell cell signaling involved in lung development	GO:0060495	1	0.017
negative regulation of cell development	GO:0010721	169	0.017
pallium development	GO:0021543	120	0.017
regulation of cell cycle	GO:0051726	281	0.017
regulation of intracellular transport	GO:0032386	159	0.017
regulation of cell projection organization	GO:0031344	206	0.017
cellular protein complex assembly	GO:0043623	116	0.017
protein targeting	GO:0006605	143	0.017
positive regulation of voltage gated calcium channel activity	GO:1901387	2	0.017
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.017
establishment or maintenance of neuroblast polarity	GO:0045196	1	0.017
regulation of epithelial cell proliferation	GO:0050678	141	0.017
negative regulation of nervous system development	GO:0051961	156	0.016
transmission of nerve impulse	GO:0019226	76	0.016
cellular amino acid metabolic process	GO:0006520	103	0.016
microtubule cytoskeleton organization	GO:0000226	157	0.016
regulation of mapk cascade	GO:0043408	248	0.016
microtubule based movement	GO:0007018	84	0.016
regulation of inflammatory response	GO:0050727	147	0.016
digestive system development	GO:0055123	200	0.016
positive regulation of thymocyte migration	GO:2000412	2	0.016
striated muscle contraction	GO:0006941	45	0.016
protein polymerization	GO:0051258	57	0.016
stem cell differentiation	GO:0048863	268	0.015
ameboidal type cell migration	GO:0001667	128	0.015
respiratory tube development	GO:0030323	167	0.015
notch signaling pathway	GO:0007219	71	0.015
lung development	GO:0030324	164	0.015
maintenance of location	GO:0051235	89	0.015
positive regulation of protein kinase b signaling	GO:0051897	32	0.015
neural precursor cell proliferation	GO:0061351	121	0.015
cellular chemical homeostasis	GO:0055082	215	0.015
myeloid cell homeostasis	GO:0002262	114	0.015
camera type eye development	GO:0043010	266	0.015
cell adhesion mediated by integrin	GO:0033627	18	0.014
single organism nuclear import	GO:1902593	95	0.014
cellular lipid metabolic process	GO:0044255	323	0.014
dna metabolic process	GO:0006259	303	0.014
oocyte axis specification	GO:0007309	2	0.014
hindbrain development	GO:0030902	128	0.014
cell adhesion	GO:0007155	329	0.014
single organismal cell cell adhesion	GO:0016337	131	0.014
positive regulation of mapk cascade	GO:0043410	170	0.014
cellular protein catabolic process	GO:0044257	155	0.014
nuclear transport	GO:0051169	139	0.014
regulation of protein localization	GO:0032880	231	0.014
positive regulation of cell cycle	GO:0045787	92	0.014
cellular calcium ion homeostasis	GO:0006874	119	0.014
thymocyte migration	GO:0072679	2	0.014
cellular ketone metabolic process	GO:0042180	84	0.014
cell activation involved in immune response	GO:0002263	126	0.013
ventral spinal cord interneuron fate commitment	GO:0060579	14	0.013
acute inflammatory response	GO:0002526	41	0.013
epidermis development	GO:0008544	187	0.013
regulation of homeostatic process	GO:0032844	182	0.013
lung pattern specification process	GO:0060432	1	0.013
b cell differentiation	GO:0030183	78	0.013
positive regulation of cell motility	GO:2000147	116	0.013
innate immune response	GO:0045087	157	0.013
glycerolipid metabolic process	GO:0046486	122	0.013
negative regulation of molecular function	GO:0044092	258	0.013
cellular response to biotic stimulus	GO:0071216	92	0.013
positive regulation of protein catabolic process	GO:0045732	60	0.013
carbohydrate metabolic process	GO:0005975	230	0.013
response to growth factor	GO:0070848	198	0.013
regulation of microtubule based process	GO:0032886	52	0.013
memory	GO:0007613	58	0.013
regulation of ion homeostasis	GO:2000021	64	0.013
divalent inorganic cation homeostasis	GO:0072507	138	0.013
negative regulation of immune effector process	GO:0002698	55	0.013
asymmetric stem cell division	GO:0098722	3	0.013
male anatomical structure morphogenesis	GO:0090598	4	0.012
eosinophil migration	GO:0072677	3	0.012
regulation of t cell costimulation	GO:2000523	2	0.012
regulation of cellular component size	GO:0032535	121	0.012
heterocycle catabolic process	GO:0046700	280	0.012
regulation of protein catabolic process	GO:0042176	108	0.012
regulation of ph	GO:0006885	26	0.012
regulation of lymphocyte differentiation	GO:0045619	107	0.012
establishment of organelle localization	GO:0051656	122	0.012
regulation of t cell activation	GO:0050863	170	0.012
regulation of defense response	GO:0031347	233	0.012
endodermal cell fate specification	GO:0001714	4	0.012
protein processing	GO:0016485	163	0.012
positive regulation of t cell differentiation	GO:0045582	52	0.012
regulation of anatomical structure size	GO:0090066	178	0.012
regulation of protein transport	GO:0051223	163	0.012
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.012
learning or memory	GO:0007611	148	0.012
cellular amine metabolic process	GO:0044106	44	0.012
gonad development	GO:0008406	141	0.012
neuromuscular process	GO:0050905	99	0.012
spinal cord oligodendrocyte cell differentiation	GO:0021529	3	0.011
aromatic compound catabolic process	GO:0019439	286	0.011
cardiac muscle tissue development	GO:0048738	130	0.011
regulation of secretion by cell	GO:1903530	249	0.011
positive regulation of calcium ion transport	GO:0051928	27	0.011
regulation of antigen receptor mediated signaling pathway	GO:0050854	29	0.011
anion transport	GO:0006820	177	0.011
regulation of wnt signaling pathway	GO:0030111	123	0.011
t cell receptor signaling pathway	GO:0050852	46	0.011
plasma membrane organization	GO:0007009	90	0.011
cytokine metabolic process	GO:0042107	71	0.011
development of primary sexual characteristics	GO:0045137	143	0.011
negative regulation of t cell activation	GO:0050868	65	0.011
regulation of lymphocyte mediated immunity	GO:0002706	84	0.011
positive regulation of eosinophil migration	GO:2000418	2	0.011
regulation of protein depolymerization	GO:1901879	26	0.011
ventral spinal cord development	GO:0021517	48	0.011
positive regulation of t cell activation	GO:0050870	101	0.011
coagulation	GO:0050817	78	0.011
gene silencing	GO:0016458	38	0.011
cellular response to peptide hormone stimulus	GO:0071375	92	0.011
cell fate specification	GO:0001708	72	0.011
regulation of calcium ion transport	GO:0051924	69	0.011
positive regulation of transferase activity	GO:0051347	167	0.011
oogenesis	GO:0048477	56	0.011
skeletal system development	GO:0001501	356	0.010
cell substrate adhesion	GO:0031589	130	0.010
regulation of t cell differentiation	GO:0045580	83	0.010
telencephalon development	GO:0021537	186	0.010
organelle fission	GO:0048285	170	0.010
chromatin modification	GO:0016568	187	0.010
intracellular protein transport	GO:0006886	204	0.010
protein maturation	GO:0051604	176	0.010
cerebral cortex cell migration	GO:0021795	44	0.010
regulation of organelle organization	GO:0033043	289	0.010
globus pallidus development	GO:0021759	2	0.010
macromolecular complex disassembly	GO:0032984	43	0.010
organonitrogen compound catabolic process	GO:1901565	264	0.010
digestive tract development	GO:0048565	190	0.010
respiratory system development	GO:0060541	190	0.010
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.010

Catsper1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.021
	nervous system disease	DOID:863	0	0.021

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network