Mus musculus

31 known processes

Fah

fumarylacetoacetate hydrolase

Fah biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442553230.145
glycerolipid metabolic processGO:00464861220.132
cellular amino acid metabolic processGO:00065201030.111
cellular amine metabolic processGO:0044106440.093
oxidation reduction processGO:00551143420.085
nucleobase containing small molecule metabolic processGO:00550863520.084
cation transmembrane transportGO:00986552660.079
cation transportGO:00068123990.074
lipid biosynthetic processGO:00086101790.073
regulation of cellular amino acid metabolic processGO:000652150.072
cellular modified amino acid metabolic processGO:0006575630.071
monocarboxylic acid metabolic processGO:00327871910.070
neutral lipid metabolic processGO:0006638570.069
synaptic transmissionGO:00072683290.068
transmembrane transportGO:00550854120.065
nucleoside phosphate metabolic processGO:00067533380.065
negative regulation of phosphorus metabolic processGO:00105631840.064
coenzyme metabolic processGO:0006732520.060
amine metabolic processGO:0009308450.057
organonitrogen compound biosynthetic processGO:19015661920.056
cofactor metabolic processGO:0051186800.052
ion transmembrane transportGO:00342203610.049
small molecule catabolic processGO:0044282710.047
glutathione metabolic processGO:0006749160.045
regulation of cellular amine metabolic processGO:0033238200.045
cholesterol metabolic processGO:0008203560.045
acylglycerol metabolic processGO:0006639550.044
sulfur compound metabolic processGO:00067901000.044
organonitrogen compound catabolic processGO:19015652640.043
positive regulation of protein modification processGO:00314012990.042
positive regulation of cellular amine metabolic processGO:003324050.040
nucleotide metabolic processGO:00091173320.039
inorganic cation transmembrane transportGO:00986622070.039
actin cytoskeleton organizationGO:00300362200.038
alcohol metabolic processGO:00060661160.038
regulation of protein kinase activityGO:00458592320.037
acetate metabolic processGO:000608310.036
regulation of cellular ketone metabolic processGO:0010565660.036
response to organonitrogen compoundGO:00102432460.036
positive regulation of protein phosphorylationGO:00019342420.035
negative regulation of protein metabolic processGO:00512482820.035
membrane organizationGO:00610242450.035
negative regulation of cellular protein metabolic processGO:00322692470.034
fatty acid metabolic processGO:00066311210.034
carbohydrate metabolic processGO:00059752300.034
anion transportGO:00068201770.034
inorganic ion transmembrane transportGO:00986602340.033
response to organic cyclic compoundGO:00140701980.032
purine containing compound metabolic processGO:00725213110.032
purine ribonucleotide metabolic processGO:00091502900.032
carboxylic acid biosynthetic processGO:0046394860.031
regulation of kinase activityGO:00435492490.031
organic hydroxy compound metabolic processGO:19016152030.031
cellular chemical homeostasisGO:00550822150.031
brown fat cell differentiationGO:0050873360.030
lipid catabolic processGO:0016042690.030
organic cyclic compound catabolic processGO:19013612950.029
small molecule biosynthetic processGO:00442831320.029
cell adhesionGO:00071553290.029
negative regulation of cell proliferationGO:00082852960.029
glycosyl compound metabolic processGO:19016572460.028
organic acid biosynthetic processGO:0016053860.028
cellular ketone metabolic processGO:0042180840.028
nitrogen compound transportGO:00717052710.028
organic anion transportGO:00157111370.028
carbohydrate derivative biosynthetic processGO:19011371830.027
sterol metabolic processGO:0016125580.026
regulation of hormone levelsGO:00108172110.026
regulation of transferase activityGO:00513382630.026
alpha amino acid metabolic processGO:1901605590.026
ribonucleoside metabolic processGO:00091192450.026
cellular nitrogen compound catabolic processGO:00442702800.025
cellular response to organonitrogen compoundGO:00714171450.025
regulation of membrane potentialGO:00423911920.025
aromatic compound catabolic processGO:00194392860.025
regulation of lipid metabolic processGO:00192161180.025
negative regulation of cellular amino acid metabolic processGO:004576300.025
reactive nitrogen species metabolic processGO:200105700.025
acylglycerol biosynthetic processGO:0046463180.025
triglyceride metabolic processGO:0006641510.024
ribose phosphate metabolic processGO:00196932910.024
glycerolipid biosynthetic processGO:0045017500.024
negative regulation of molecular functionGO:00440922580.024
carboxylic acid catabolic processGO:0046395510.023
hematopoietic progenitor cell differentiationGO:00022441430.023
cell type specific apoptotic processGO:00972852680.023
innate immune responseGO:00450871570.023
positive regulation of transferase activityGO:00513471670.022
regulation of hydrolase activityGO:00513362460.022
regulation of chloride transportGO:200122520.022
immune effector processGO:00022523210.022
cellular amide metabolic processGO:0043603580.022
fat cell differentiationGO:00454441600.022
ribonucleotide metabolic processGO:00092592910.022
cellular lipid catabolic processGO:0044242520.022
spermatogenesisGO:00072832840.022
purine nucleoside metabolic processGO:00422782410.022
regulation of organelle organizationGO:00330432890.022
isoprenoid metabolic processGO:0006720290.021
metal ion homeostasisGO:00550651890.021
peptidyl amino acid modificationGO:00181933360.021
multicellular organismal homeostasisGO:00488711640.021
nadph regenerationGO:000674020.021
reactive oxygen species metabolic processGO:0072593840.021
g protein coupled receptor signaling pathwayGO:00071862430.021
hexose metabolic processGO:0019318980.021
glycosyl compound catabolic processGO:19016582060.021
cellular ion homeostasisGO:00068731650.020
regulation of cell cycleGO:00517262810.020
negative regulation of protein modification processGO:00314001630.020
regulation of cytokine productionGO:00018172660.020
regulation of cellular catabolic processGO:00313292420.020
organophosphate biosynthetic processGO:00904071220.020
lipid modificationGO:0030258650.020
negative regulation of intracellular signal transductionGO:19025321670.020
positive regulation of cell deathGO:00109422240.020
thioester metabolic processGO:0035383190.020
negative regulation of phosphorylationGO:00423261660.020
purine nucleotide metabolic processGO:00061633020.020
male gamete generationGO:00482322850.020
circulatory system processGO:00030131970.020
cofactor transportGO:005118140.020
bile acid secretionGO:003278220.020
negative regulation of phosphate metabolic processGO:00459361840.020
negative regulation of neuron deathGO:1901215980.020
regulation of apoptotic signaling pathwayGO:20012331970.019
intracellular protein transportGO:00068862040.019
regulation of transmembrane transportGO:00347621280.019
protein maturationGO:00516041760.019
fat soluble vitamin biosynthetic processGO:004236240.019
regulation of mapk cascadeGO:00434082480.019
response to radiationGO:00093141650.019
negative regulation of protein processingGO:0010955790.019
amide transportGO:00428861380.019
cellular response to cytokine stimulusGO:00713451890.019
apoptotic signaling pathwayGO:00971903060.019
polyamine catabolic processGO:000659820.019
positive regulation of cellular amino acid metabolic processGO:004576430.019
cellular homeostasisGO:00197252400.019
ossificationGO:00015032160.019
sensory perceptionGO:00076002450.019
response to acid chemicalGO:00011011110.019
terpenoid metabolic processGO:0006721250.019
fatty acid biosynthetic processGO:0006633410.018
protein processingGO:00164851630.018
lateral inhibitionGO:004633110.018
positive regulation of protein kinase activityGO:00458601440.018
gland developmentGO:00487323300.018
positive regulation of kinase activityGO:00336741550.018
maintenance of locationGO:0051235890.018
purine ribonucleotide catabolic processGO:00091542080.018
steroid metabolic processGO:00082021190.018
chemotaxisGO:00069352470.018
heterocycle catabolic processGO:00467002800.018
cation homeostasisGO:00550802120.018
lipid homeostasisGO:0055088630.018
regulation of homeostatic processGO:00328441820.017
defense response to other organismGO:00985421970.017
regulation of intracellular transportGO:00323861590.017
t cell activationGO:00421102890.017
response to molecule of bacterial originGO:00022371430.017
ribonucleoside bisphosphate metabolic processGO:003387590.017
negative regulation of cellular amine metabolic processGO:003323910.017
neuron deathGO:00709971540.017
cytokine productionGO:00018163190.017
regulation of reactive oxygen species metabolic processGO:2000377400.017
reactive oxygen species biosynthetic processGO:190340980.017
posttranscriptional regulation of gene expressionGO:00106081550.017
muscle system processGO:00030121410.017
organophosphate catabolic processGO:00464342320.017
ribonucleotide catabolic processGO:00092612080.016
peptide metabolic processGO:0006518460.016
lipid localizationGO:00108761260.016
inflammatory responseGO:00069542440.016
dephosphorylationGO:00163111290.016
cellular alcohol metabolic processGO:004410730.016
ribonucleoside catabolic processGO:00424542060.016
positive regulation of hydrolase activityGO:00513451480.016
positive regulation of mapk cascadeGO:00434101700.016
leukocyte migrationGO:00509001240.016
ribonucleoside triphosphate metabolic processGO:00091992200.016
monosaccharide metabolic processGO:00059961060.016
glycerophospholipid metabolic processGO:0006650710.016
response to light stimulusGO:00094161350.016
regulation of defense responseGO:00313472330.015
monocarboxylic acid biosynthetic processGO:0072330610.015
regulation of cell activationGO:00508652890.015
acyl coa metabolic processGO:0006637190.015
tissue homeostasisGO:00018941150.015
neuron neuron synaptic transmissionGO:0007270690.015
carbohydrate derivative catabolic processGO:19011362310.015
camera type eye developmentGO:00430102660.015
purine containing compound catabolic processGO:00725232130.015
nucleoside bisphosphate metabolic processGO:003386590.015
regulation of neuron deathGO:19012141340.015
regulation of reactive oxygen species biosynthetic processGO:190342620.015
ear developmentGO:00435832000.015
purine ribonucleoside catabolic processGO:00461302050.015
triglyceride biosynthetic processGO:0019432170.015
regulation of cytoskeleton organizationGO:00514931220.015
carbohydrate homeostasisGO:00335001280.015
sensory organ morphogenesisGO:00905962420.015
cellular response to organic cyclic compoundGO:0071407870.015
regulation of establishment of protein localizationGO:00702011810.015
organic acid catabolic processGO:0016054510.015
cellular response to hormone stimulusGO:00328701500.015
cytoplasmic transportGO:00164822340.015
protein localization to organelleGO:00333651850.015
purine nucleoside catabolic processGO:00061522050.015
nucleoside phosphate biosynthetic processGO:1901293790.014
negative regulation of neuron apoptotic processGO:0043524920.014
calcium ion transmembrane transportGO:0070588850.014
regulation of proteolysisGO:00301621640.014
endomembrane system organizationGO:00102561470.014
purine nucleotide catabolic processGO:00061952110.014
positive regulation of apoptotic processGO:00430652170.014
nucleoside metabolic processGO:00091162460.014
positive regulation of cellular ph reductionGO:003284920.014
muscle contractionGO:00069361010.014
mapk cascadeGO:00001652810.014
transmission of nerve impulseGO:0019226760.014
multi multicellular organism processGO:00447061090.014
positive regulation of nucleotide metabolic processGO:00459811140.014
cellular alcohol biosynthetic processGO:004410830.014
renal system developmentGO:00720012250.014
macromolecule catabolic processGO:00090572810.014
heart processGO:0003015940.014
regulation of anatomical structure sizeGO:00900661780.014
regulation of protein serine threonine kinase activityGO:00719001570.014
positive regulation of purine nucleotide metabolic processGO:19005441140.014
nucleoside phosphate catabolic processGO:19012922220.014
cell activation involved in immune responseGO:00022631260.014
carboxylic acid transportGO:00469421000.014
urogenital system developmentGO:00016552610.014
positive regulation of nervous system developmentGO:00519622210.014
adiponectin activated signaling pathwayGO:003321140.014
plasma membrane organizationGO:0007009900.014
regulation of cholesterol metabolic processGO:0090181140.014
cognitionGO:00508901490.014
glucose metabolic processGO:0006006920.013
purine containing compound biosynthetic processGO:0072522700.013
response to extracellular stimulusGO:00099911270.013
response to oxygen levelsGO:0070482620.013
response to nutrient levelsGO:00316671090.013
positive regulation of secretionGO:00510471300.013
nucleoside catabolic processGO:00091642060.013
very long chain fatty acid catabolic processGO:004276020.013
leukocyte activation involved in immune responseGO:00023661260.013
kidney developmentGO:00018222130.013
positive regulation of cytokine productionGO:00018191740.013
endocytosisGO:00068971680.013
anion transmembrane transportGO:0098656710.013
retinoid metabolic processGO:0001523240.013
cytokine mediated signaling pathwayGO:00192211150.013
epidermis developmentGO:00085441870.013
negative regulation of protein phosphorylationGO:00019331260.013
cellular metal ion homeostasisGO:00068751510.013
positive regulation of reactive oxygen species metabolic processGO:2000379110.013
nucleocytoplasmic transportGO:00069131390.013
positive regulation of programmed cell deathGO:00430682180.013
midgut developmentGO:000749440.013
methylationGO:00322591340.013
cellular response to peptideGO:1901653920.013
response to insulinGO:00328681000.013
regulation of secretionGO:00510462740.013
striated muscle tissue developmentGO:00147062930.013
substantia nigra developmentGO:002176220.013
positive regulation of protein serine threonine kinase activityGO:00719021060.013
regulation of ion transmembrane transportGO:00347651190.013
c4 dicarboxylate transportGO:001574030.013
nucleoside triphosphate metabolic processGO:00091412300.013
negative regulation of proteolysisGO:0045861740.013
organic acid transportGO:00158491010.013
blood circulationGO:00080151950.013
regulation of protein localizationGO:00328802310.013
divalent inorganic cation homeostasisGO:00725071380.013
cellular amino acid biosynthetic processGO:0008652220.013
regulation of epithelial cell proliferationGO:00506781410.012
cell substrate adhesionGO:00315891300.012
multicellular organismal signalingGO:0035637910.012
negative regulation of cell developmentGO:00107211690.012
skeletal system morphogenesisGO:00487052030.012
regulation of secretion by cellGO:19035302490.012
rhythmic processGO:00485111740.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.012
ras protein signal transductionGO:0007265770.012
nucleotide catabolic processGO:00091662170.012
regulation of system processGO:00440572000.012
axonogenesisGO:00074092740.012
cellular response to acid chemicalGO:0071229680.012
homeostasis of number of cellsGO:00488722100.012
regulation of blood pressureGO:0008217930.012
regulation of neuron projection developmentGO:00109751690.012
neuronal action potentialGO:0019228540.012
regulation of cellular component biogenesisGO:00440871810.012
monosaccharide transportGO:0015749580.012
regulation of adaptive immune responseGO:0002819900.012
muscle tissue developmentGO:00605373080.012
negative regulation of immune system processGO:00026832090.012
coenzyme a metabolic processGO:001593680.012
purine nucleoside triphosphate metabolic processGO:00091442260.012
dna metabolic processGO:00062593030.012
cellular response to lipidGO:00713961450.012
adaptive immune responseGO:00022501550.012
response to peptide hormoneGO:00434341270.012
regulation of protein transportGO:00512231630.012
dendrite developmentGO:00163581150.012
coenzyme biosynthetic processGO:0009108230.012
embryonic organ morphogenesisGO:00485622760.012
leukocyte differentiationGO:00025213420.012
lymphocyte mediated immunityGO:00024491390.012
negative regulation of protein maturationGO:1903318790.012
skeletal system developmentGO:00015013560.012
organelle fissionGO:00482851700.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
negative regulation of transferase activityGO:0051348850.011
divalent inorganic cation transportGO:00725111780.011
negative regulation of growthGO:0045926990.011
epithelial cell proliferationGO:00506731740.011
multicellular organism growthGO:00352641610.011
Worm
epithelial cell developmentGO:00020641590.011
negative regulation of cellular component organizationGO:00511291940.011
bone developmentGO:00603481200.011
regulation of neuron differentiationGO:00456642810.011
regulation of protein maturationGO:1903317960.011
ribonucleoside triphosphate catabolic processGO:00092031990.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
regulation of leukocyte differentiationGO:19021051590.011
sulfur compound biosynthetic processGO:0044272370.011
lymphocyte activation involved in immune responseGO:0002285930.011
diacylglycerol biosynthetic processGO:000665120.011
coenzyme catabolic processGO:000910950.011
regulation of cell projection organizationGO:00313442060.011
regulation of triglyceride biosynthetic processGO:0010866100.011
organ growthGO:00352651170.011
transition metal ion transportGO:0000041380.011
ribose phosphate biosynthetic processGO:0046390590.011
cellular response to cadmium ionGO:007127630.011
organelle localizationGO:00516401790.011
skin developmentGO:00435882200.011
regulation of lymphocyte activationGO:00512492400.011
positive regulation of cellular catabolic processGO:00313311480.011
phosphatidic acid biosynthetic processGO:000665420.011
regulation of cell motilityGO:20001452360.011
pyruvate metabolic processGO:0006090280.011
hexose transportGO:0008645560.011
regulation of cytoplasmic transportGO:19036491120.011
defense response to bacteriumGO:00427421190.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
regulation of nucleotide metabolic processGO:00061401690.011
regulation of endopeptidase activityGO:0052548890.011
positive regulation of nucleoside metabolic processGO:0045979910.011
regulation of voltage gated calcium channel activityGO:190138540.011
divalent metal ion transportGO:00708381720.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
developmental maturationGO:00217001930.011
regulation of bindingGO:00510981110.010
negative regulation of complement activationGO:004591630.010
nuclear transportGO:00511691390.010
heart morphogenesisGO:00030071780.010
t cell differentiationGO:00302171740.010
rho protein signal transductionGO:0007266320.010
embryonic placenta developmentGO:0001892980.010
response to epidermal growth factorGO:007084940.010
small gtpase mediated signal transductionGO:0007264970.010
regulation of t cell activationGO:00508631700.010
negative regulation of neuron differentiationGO:00456651010.010
oxidoreduction coenzyme metabolic processGO:0006733160.010
neutral lipid biosynthetic processGO:0046460180.010
regulation of lymphocyte mediated immunityGO:0002706840.010
locomotory behaviorGO:00076261950.010
regulation of neuron apoptotic processGO:00435231220.010
regulation of lipid biosynthetic processGO:0046890540.010
regulation of ossificationGO:00302781120.010
nucleotide biosynthetic processGO:0009165780.010
exocytosisGO:00068871210.010
regulation of multi organism processGO:00439001110.010
learning or memoryGO:00076111480.010
regulation of ion transportGO:00432692150.010
lymphocyte differentiationGO:00300982420.010
alpha amino acid catabolic processGO:1901606180.010
regulation of synaptic plasticityGO:0048167870.010
membrane lipid biosynthetic processGO:0046467320.010

Fah disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.076
inherited metabolic disorderDOID:65500.059
disease of anatomical entityDOID:700.020
nervous system diseaseDOID:86300.020
immune system diseaseDOID:291400.017
central nervous system diseaseDOID:33100.014
lipid metabolism disorderDOID:314600.014
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012
primary immunodeficiency diseaseDOID:61200.011