| microtubule polymerization or depolymerization | GO:0031109 | 26 | 0.241 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.239 | Yeast |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.211 | Yeast |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.173 | |
| regulation of microtubule based process | GO:0032886 | 52 | 0.172 | |
| cellular response to misfolded protein | GO:0071218 | 5 | 0.171 | |
| microtubule based process | GO:0007017 | 236 | 0.157 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.155 | Yeast |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.149 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.122 | |
| protein complex disassembly | GO:0043241 | 40 | 0.121 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.118 | |
| cellular response to starvation | GO:0009267 | 57 | 0.116 | |
| chromatin modification | GO:0016568 | 187 | 0.115 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.114 | Yeast |
| regulation of receptor activity | GO:0010469 | 41 | 0.113 | |
| chromatin organization | GO:0006325 | 206 | 0.108 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.105 | Yeast |
| protein processing | GO:0016485 | 163 | 0.098 | |
| regulation of protein localization | GO:0032880 | 231 | 0.098 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.095 | Yeast |
| regulation of protein maturation | GO:1903317 | 96 | 0.095 | |
| cellular response to nutrient levels | GO:0031669 | 64 | 0.095 | |
| protein ubiquitination | GO:0016567 | 171 | 0.092 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.083 | |
| protein catabolic process | GO:0030163 | 221 | 0.081 | Yeast |
| cellular protein complex assembly | GO:0043623 | 116 | 0.081 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.077 | Yeast |
| regulation of proteolysis | GO:0030162 | 164 | 0.073 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.071 | |
| protein maturation | GO:0051604 | 176 | 0.071 | |
| histone modification | GO:0016570 | 159 | 0.071 | |
| protein depolymerization | GO:0051261 | 34 | 0.069 | |
| response to misfolded protein | GO:0051788 | 5 | 0.067 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.067 | |
| intracellular protein transport | GO:0006886 | 204 | 0.067 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.066 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.064 | |
| regulation of microtubule polymerization or depolymerization | GO:0031110 | 20 | 0.064 | |
| regulation of cell migration | GO:0030334 | 219 | 0.062 | |
| regulation of protein processing | GO:0070613 | 96 | 0.059 | |
| macroautophagy | GO:0016236 | 21 | 0.058 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.057 | |
| epithelium migration | GO:0090132 | 63 | 0.056 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.056 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.055 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.053 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.053 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.053 | |
| macromolecular complex disassembly | GO:0032984 | 43 | 0.052 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.051 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.050 | |
| microtubule depolymerization | GO:0007019 | 15 | 0.049 | |
| macromolecule deacylation | GO:0098732 | 37 | 0.049 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.049 | |
| response to inorganic substance | GO:0010035 | 96 | 0.048 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.047 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.046 | |
| regulation of cell motility | GO:2000145 | 236 | 0.046 | |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.046 | |
| negative regulation of microtubule polymerization or depolymerization | GO:0031111 | 15 | 0.046 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.045 | |
| cellular response to extracellular stimulus | GO:0031668 | 81 | 0.045 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.045 | |
| organelle localization | GO:0051640 | 179 | 0.044 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.044 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.042 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.040 | |
| response to reactive oxygen species | GO:0000302 | 56 | 0.040 | |
| inclusion body assembly | GO:0070841 | 3 | 0.040 | |
| cellular response to topologically incorrect protein | GO:0035967 | 25 | 0.040 | |
| ameboidal type cell migration | GO:0001667 | 128 | 0.040 | |
| negative regulation of protein depolymerization | GO:1901880 | 21 | 0.040 | |
| response to starvation | GO:0042594 | 65 | 0.038 | |
| fat cell differentiation | GO:0045444 | 160 | 0.037 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.037 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.037 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.036 | |
| protein deacetylation | GO:0006476 | 32 | 0.036 | |
| protein modification by small protein removal | GO:0070646 | 21 | 0.036 | |
| response to oxidative stress | GO:0006979 | 123 | 0.036 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.035 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.035 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.035 | |
| tubulin deacetylation | GO:0090042 | 4 | 0.035 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.035 | |
| tissue migration | GO:0090130 | 68 | 0.034 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.034 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.034 | |
| regulation of microtubule cytoskeleton organization | GO:0070507 | 37 | 0.034 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.033 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.032 | |
| regulation of response to oxidative stress | GO:1902882 | 19 | 0.032 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.032 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.031 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.031 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.031 | |
| ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway | GO:0043162 | 3 | 0.031 | |
| aggresome assembly | GO:0070842 | 2 | 0.031 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.031 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.031 | |
| response to growth factor | GO:0070848 | 198 | 0.031 | |
| amine metabolic process | GO:0009308 | 45 | 0.030 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.030 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.030 | |
| chromosome segregation | GO:0007059 | 48 | 0.030 | |
| autophagy | GO:0006914 | 45 | 0.030 | |
| negative regulation of microtubule depolymerization | GO:0007026 | 13 | 0.030 | |
| regulation of protein depolymerization | GO:1901879 | 26 | 0.030 | |
| regulation of microtubule depolymerization | GO:0031114 | 13 | 0.029 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.029 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.028 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.028 | |
| nuclear division | GO:0000280 | 158 | 0.028 | |
| organelle fission | GO:0048285 | 170 | 0.028 | |
| regulation of protein complex disassembly | GO:0043244 | 28 | 0.028 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.027 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.027 | |
| cellular protein complex disassembly | GO:0043624 | 36 | 0.027 | |
| response to hydrogen peroxide | GO:0042542 | 32 | 0.027 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.027 | |
| positive regulation of cell motility | GO:2000147 | 116 | 0.027 | |
| receptor biosynthetic process | GO:0032800 | 3 | 0.026 | |
| histone deacetylation | GO:0016575 | 26 | 0.026 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.026 | |
| regulation of cellular response to oxidative stress | GO:1900407 | 19 | 0.026 | |
| negative regulation of cytoskeleton organization | GO:0051494 | 36 | 0.025 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.025 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.025 | |
| protein deacylation | GO:0035601 | 36 | 0.025 | |
| negative regulation of protein complex disassembly | GO:0043242 | 22 | 0.025 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.024 | |
| regulation of fat cell differentiation | GO:0045598 | 81 | 0.024 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.024 | |
| maintenance of location | GO:0051235 | 89 | 0.023 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.023 | |
| epithelial cell migration | GO:0010631 | 63 | 0.023 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.023 | |
| organelle assembly | GO:0070925 | 177 | 0.023 | |
| dna metabolic process | GO:0006259 | 303 | 0.023 | Yeast |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.022 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.022 | |
| peptidyl lysine deacetylation | GO:0034983 | 1 | 0.021 | |
| male gamete generation | GO:0048232 | 285 | 0.021 | |
| cation transport | GO:0006812 | 399 | 0.021 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.020 | |
| rna processing | GO:0006396 | 105 | 0.020 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.020 | |
| misfolded or incompletely synthesized protein catabolic process | GO:0006515 | 4 | 0.020 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.019 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.019 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.019 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.019 | |
| protein targeting | GO:0006605 | 143 | 0.018 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.018 | |
| cellular homeostasis | GO:0019725 | 240 | 0.018 | Yeast |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.018 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.018 | |
| compound eye development | GO:0048749 | 1 | 0.018 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.018 | |
| developmental maturation | GO:0021700 | 193 | 0.018 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.018 | |
| transmembrane transport | GO:0055085 | 412 | 0.017 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.017 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.017 | |
| regulation of epithelial cell migration | GO:0010632 | 35 | 0.017 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.017 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.017 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.017 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.017 | |
| regionalization | GO:0003002 | 337 | 0.017 | |
| membrane organization | GO:0061024 | 245 | 0.016 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.016 | |
| rna interference | GO:0016246 | 2 | 0.016 | |
| cell division | GO:0051301 | 120 | 0.016 | |
| immune effector process | GO:0002252 | 321 | 0.016 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.016 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.016 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.016 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.016 | |
| dephosphorylation | GO:0016311 | 129 | 0.016 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.016 | |
| regulation of secretion | GO:0051046 | 274 | 0.016 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.015 | |
| maturation of 5 8s rrna | GO:0000460 | 1 | 0.015 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.015 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.015 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.015 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.015 | |
| action potential | GO:0001508 | 78 | 0.015 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 80 | 0.015 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.015 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.015 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.015 | |
| response to topologically incorrect protein | GO:0035966 | 25 | 0.014 | |
| sensory perception | GO:0007600 | 245 | 0.014 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.014 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.014 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.014 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.014 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.014 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.014 | |
| regulation of cell activation | GO:0050865 | 289 | 0.014 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.014 | |
| myosin filament organization | GO:0031033 | 3 | 0.014 | |
| regulation of receptor biosynthetic process | GO:0010869 | 2 | 0.014 | |
| germ cell development | GO:0007281 | 185 | 0.014 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.013 | |
| neuronal action potential | GO:0019228 | 54 | 0.013 | |
| stem cell differentiation | GO:0048863 | 268 | 0.013 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.013 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.013 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.013 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.013 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.013 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.013 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.013 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.013 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.013 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.013 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.013 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.013 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.013 | |
| cytokine production | GO:0001816 | 319 | 0.013 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.013 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.013 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.013 | |
| skeletal muscle organ development | GO:0060538 | 163 | 0.013 | |
| oxidation reduction process | GO:0055114 | 342 | 0.013 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.013 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.013 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.013 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.013 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.013 | |
| lipid localization | GO:0010876 | 126 | 0.012 | |
| regulation of oxidative stress induced cell death | GO:1903201 | 14 | 0.012 | |
| forebrain development | GO:0030900 | 302 | 0.012 | |
| muscle tissue development | GO:0060537 | 308 | 0.012 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.012 | |
| synapse organization | GO:0050808 | 125 | 0.012 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.012 | |
| response to radiation | GO:0009314 | 165 | 0.012 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.012 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.012 | |
| innate immune response | GO:0045087 | 157 | 0.012 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.012 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.012 | |
| skeletal system development | GO:0001501 | 356 | 0.012 | |
| gene silencing by rna | GO:0031047 | 19 | 0.012 | |
| multicellular organism growth | GO:0035264 | 161 | 0.012 | |
| gonad development | GO:0008406 | 141 | 0.012 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.012 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.012 | |
| nuclear import | GO:0051170 | 95 | 0.012 | |
| organic anion transport | GO:0015711 | 137 | 0.011 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.011 | |
| anion transport | GO:0006820 | 177 | 0.011 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.011 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.011 | |
| cellular response to lipid | GO:0071396 | 145 | 0.011 | |
| methylation | GO:0032259 | 134 | 0.011 | |
| response to light stimulus | GO:0009416 | 135 | 0.011 | |
| camera type eye development | GO:0043010 | 266 | 0.011 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.011 | |
| oocyte construction | GO:0007308 | 2 | 0.011 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.011 | |
| t cell activation | GO:0042110 | 289 | 0.011 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.011 | |
| ossification | GO:0001503 | 216 | 0.011 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.011 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.011 | |
| striated muscle myosin thick filament assembly | GO:0071688 | 1 | 0.011 | |
| locomotory behavior | GO:0007626 | 195 | 0.011 | |
| lateral inhibition | GO:0046331 | 1 | 0.011 | |
| neural tube development | GO:0021915 | 160 | 0.011 | |
| mapk cascade | GO:0000165 | 281 | 0.011 | |
| mitochondrion organization | GO:0007005 | 134 | 0.010 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 57 | 0.010 | |
| endocytosis | GO:0006897 | 168 | 0.010 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.010 | |
| positive regulation of cellular response to oxidative stress | GO:1900409 | 6 | 0.010 | |
| angiogenesis | GO:0001525 | 201 | 0.010 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.010 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.010 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.010 | |
| regulation of engulfment of apoptotic cell | GO:1901074 | 2 | 0.010 | |
| protein import into nucleus | GO:0006606 | 95 | 0.010 | |
