Mus musculus

309 known processes

Il6

interleukin 6

(Aliases: Il-6)

Il6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
interleukin 18 mediated signaling pathwayGO:003565520.999
cellular response to interleukin 18GO:007135130.997
regulation of inflammatory responseGO:00507271470.996
Human
regulation of reactive oxygen species biosynthetic processGO:190342620.979
interleukin 5 secretionGO:007260320.975
response to interleukin 1GO:0070555110.973
positive regulation of lymphocyte proliferationGO:0050671700.971
Human
positive regulation of defense responseGO:00313491240.966
Human
antibacterial peptide secretionGO:000277910.964
peptidyl tyrosine modificationGO:00182121450.963
Human
defense response to other organismGO:00985421970.961
regulation of cell activationGO:00508652890.955
positive regulation of b cell mediated immunityGO:0002714260.945
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.942
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.942
negative regulation of reactive oxygen species biosynthetic processGO:190342700.938
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.931
cellular response to cytokine stimulusGO:00713451890.930
cell killingGO:0001906670.928
positive regulation of leukocyte mediated immunityGO:0002705700.927
amine metabolic processGO:0009308450.920
cytokine productionGO:00018163190.918
immune effector processGO:00022523210.916
antibacterial peptide biosynthetic processGO:000278020.913
response to lipopolysaccharideGO:00324961280.910
regulation of cellular ketone metabolic processGO:0010565660.906
somatic diversification of immune receptorsGO:0002200530.897
adaptive immune responseGO:00022501550.891
antibacterial peptide productionGO:000277820.883
regulation of immunoglobulin productionGO:0002637420.882
Human
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.875
lymphocyte mediated immunityGO:00024491390.873
tyrosine phosphorylation of stat1 proteinGO:004250830.867
cellular amino acid metabolic processGO:00065201030.864
t cell differentiation involved in immune responseGO:0002292300.863
immunoglobulin mediated immune responseGO:0016064690.858
fever generationGO:000166070.857
positive regulation of reactive oxygen species biosynthetic processGO:190342820.855
inflammatory response to woundingGO:009059440.855
positive regulation of t helper 1 cell differentiationGO:004562740.845
leukocyte mediated immunityGO:00024431740.844
neutrophil mediated killing of gram negative bacteriumGO:007094540.843
production of molecular mediator of immune responseGO:00024401030.836
Human
innate immune responseGO:00450871570.833
lipopolysaccharide mediated signaling pathwayGO:0031663250.830
regulation of leukocyte mediated immunityGO:00027031040.824
regulation of cellular amino acid metabolic processGO:000652150.824
cellular response to lipopolysaccharideGO:0071222770.809
regulation of b cell mediated immunityGO:0002712370.789
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.778
defense response to gram positive bacteriumGO:0050830500.768
Human
positive regulation of reactive oxygen species metabolic processGO:2000379110.767
positive regulation of cellular amino acid metabolic processGO:004576430.765
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.758
b cell mediated immunityGO:0019724710.758
regulation of dna recombinationGO:0000018340.754
positive regulation of inflammatory responseGO:0050729470.750
Human
regulation of neutrophil mediated killing of gram negative bacteriumGO:007095110.747
positive regulation of cell activationGO:00508671580.741
cellular metal ion homeostasisGO:00068751510.741
cellular response to amino acid stimulusGO:0071230290.739
somatic recombination of immunoglobulin gene segmentsGO:0016447420.735
cellular amine metabolic processGO:0044106440.735
regulation of adaptive immune responseGO:0002819900.731
natural killer cell activationGO:0030101440.728
regulation of peptidyl tyrosine phosphorylationGO:0050730930.725
Human
cellular response to biotic stimulusGO:0071216920.724
regulation of response to woundingGO:19030341890.724
Human
negative regulation of cell proliferationGO:00082852960.719
negative regulation of chemokine biosynthetic processGO:004507920.717
defense response to gram negative bacteriumGO:0050829280.709
Human
inflammatory responseGO:00069542440.701
Human
cellular response to interferon gammaGO:0071346250.684
t cell activationGO:00421102890.683
defense response to bacteriumGO:00427421190.683
Human
positive regulation of isotype switching to igg isotypesGO:004830470.682
regulation of lymphocyte mediated immunityGO:0002706840.679
regulation of chemokine biosynthetic processGO:004507380.677
response to interferon gammaGO:0034341340.677
positive regulation of mapk cascadeGO:00434101700.675
Human
cd4 positive alpha beta t cell cytokine productionGO:003574340.666
reactive oxygen species biosynthetic processGO:190340980.666
regulation of chemokine productionGO:0032642300.666
regulation of mapk cascadeGO:00434082480.662
Human
regulation of chronic inflammatory response to antigenic stimulusGO:000287430.655
response to molecule of bacterial originGO:00022371430.649
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.641
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.634
myeloid leukocyte migrationGO:0097529570.633
positive regulation of cellular amine metabolic processGO:003324050.620
divalent inorganic cation homeostasisGO:00725071380.615
positive regulation of immunoglobulin mediated immune responseGO:0002891260.615
regulation of growth of symbiont in hostGO:0044126190.609
cellular calcium ion homeostasisGO:00068741190.602
regulation of cell migrationGO:00303342190.601
regulation of leukocyte proliferationGO:00706631210.600
Human
positive regulation of response to woundingGO:1903036660.600
Human
positive regulation of lymphocyte activationGO:00512511400.599
regulation of lymphocyte proliferationGO:00506701170.599
Human
negative regulation of inflammatory responseGO:0050728610.599
regulation of ion transportGO:00432692150.595
regulation of innate immune responseGO:0045088910.592
organ or tissue specific immune responseGO:0002251130.589
Human
interleukin 33 mediated signaling pathwayGO:003817210.589
chemokine productionGO:0032602340.587
regulation of cytokine productionGO:00018172660.586
regulation of chemokine secretionGO:009019640.586
natural killer cell mediated cytotoxicityGO:0042267290.583
positive regulation of macrophage activationGO:0043032100.583
wound healing involved in inflammatory responseGO:000224640.575
positive regulation of cytokine biosynthetic processGO:0042108400.574
regulation of defense responseGO:00313472330.574
Human
positive regulation by symbiont of defense related host nitric oxide productionGO:005234710.572
positive regulation of immune effector processGO:00026991070.571
circadian rhythmGO:00076231140.571
chemokine biosynthetic processGO:004203380.567
mapk cascadeGO:00001652810.564
Human
regulation of map kinase activityGO:00434051200.556
chemotaxisGO:00069352470.548
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.544
interleukin 2 biosynthetic processGO:0042094150.541
regulation of nitric oxide biosynthetic processGO:0045428180.540
positive regulation of adaptive immune responseGO:0002821610.536
protein secretionGO:00093061110.534
Human
positive regulation of neutrophil mediated cytotoxicityGO:007096010.533
alpha beta t cell activation involved in immune responseGO:0002287310.532
cellular response to organonitrogen compoundGO:00714171450.527
positive regulation of neutrophil mediated killing of symbiont cellGO:007096110.520
reactive oxygen species metabolic processGO:0072593840.517
cytokine biosynthetic processGO:0042089680.514
acute phase responseGO:0006953100.513
interleukin 10 secretionGO:007260840.512
reactive nitrogen species metabolic processGO:200105700.511
positive regulation of lymphocyte mediated immunityGO:0002708620.505
regulation of peptidase activityGO:0052547960.505
dna recombinationGO:0006310920.503
negative regulation of protein metabolic processGO:00512482820.499
regulation of lymphocyte activationGO:00512492400.494
detection of molecule of bacterial originGO:003249020.493
thymocyte migrationGO:007267920.492
positive regulation of cytokine productionGO:00018191740.491
Human
leukocyte homeostasisGO:0001776790.484
i kappab kinase nf kappab signalingGO:0007249850.484
cellular ketone metabolic processGO:0042180840.480
positive regulation of t cell proliferationGO:0042102520.468
Human
response to interleukin 4GO:0070670230.467
interleukin 11 mediated signaling pathwayGO:003815420.462
response to organic cyclic compoundGO:00140701980.461
Human
tyrosine phosphorylation of stat proteinGO:0007260230.457
Human
granulocyte chemotaxisGO:0071621390.457
cytokine mediated signaling pathwayGO:00192211150.455
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.451
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.450
Human
cell activation involved in immune responseGO:00022631260.441
regulation of protein transportGO:00512231630.441
Human
positive regulation by symbiont of host immune responseGO:005255610.440
gland developmentGO:00487323300.438
positive regulation of glial cell proliferationGO:006025240.438
regulation of establishment of protein localizationGO:00702011810.435
Human
lymphocyte proliferationGO:00466511640.433
Human
negative regulation of cell activationGO:00508661110.431
negative regulation of myoblast differentiationGO:0045662180.424
regulation of adrenergic receptor signaling pathwayGO:007187740.422
regulation of leukocyte mediated cytotoxicityGO:0001910380.421
t helper 2 cell cytokine productionGO:003574540.417
regulation of cellular amine metabolic processGO:0033238200.416
isotype switching to ige isotypesGO:004828970.415
regulation of neutrophil mediated killing of fungusGO:007095310.413
regulation of isotype switchingGO:0045191220.410
cellular chemical homeostasisGO:00550822150.410
myeloid leukocyte activationGO:0002274830.409
regulation of acute inflammatory responseGO:0002673270.407
Human
regulation of t cell proliferationGO:0042129920.406
Human
positive regulation of natural killer cell activationGO:0032816150.401
placenta developmentGO:00018901400.397
calcium ion transportGO:00068161590.397
negative regulation of interleukin 5 secretionGO:200066310.396
regulation of insulin receptor signaling pathwayGO:0046626210.385
alpha beta t cell proliferationGO:0046633210.376
alpha beta t cell differentiation involved in immune responseGO:0002293300.373
necroptotic signaling pathwayGO:009752730.372
regulation of t helper 1 cell differentiationGO:004562570.370
antimicrobial peptide secretionGO:000277610.367
alpha beta t cell activationGO:0046631910.365
response to glucocorticoidGO:0051384200.361
Human
cellular response to interleukin 4GO:0071353210.361
regulation of reactive oxygen species metabolic processGO:2000377400.360
response to lithium ionGO:0010226100.359
negative regulation of molecular functionGO:00440922580.358
positive regulation of interferon gamma productionGO:0032729390.358
response to tumor necrosis factorGO:0034612260.358
regulation of fever generationGO:003162060.356
regulation of cell motilityGO:20001452360.356
isotype switchingGO:0045190360.355
regulation of immunoglobulin mediated immune responseGO:0002889370.353
regulation of protein oligomerizationGO:003245940.351
modification of morphology or physiology of other organism involved in symbiotic interactionGO:0051817160.349
positive regulation of natural killer cell mediated immunityGO:0002717160.349
t helper 1 cell differentiationGO:0045063130.344
regulation of cytokine production involved in immune responseGO:0002718260.341
interleukin 6 biosynthetic processGO:0042226120.341
interleukin 27 mediated signaling pathwayGO:007010610.340
chemokine secretionGO:009019550.333
regulation of cytokine biosynthetic processGO:0042035590.330
leukocyte differentiationGO:00025213420.330
cellular response to lipidGO:00713961450.328
positive regulation of leukocyte proliferationGO:0070665730.326
Human
rhythmic processGO:00485111740.326
regulation of interleukin 6 biosynthetic processGO:0045408110.325
regulation of syncytium formation by plasma membrane fusionGO:0060142230.324
myotube differentiationGO:00149021050.322
alpha amino acid catabolic processGO:1901606180.322
peptidyl amino acid modificationGO:00181933360.314
Human
peptide transportGO:00158331330.311
regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042430.310
cellular response to molecule of bacterial originGO:0071219830.310
response to oxygen levelsGO:0070482620.308
leukocyte activation involved in immune responseGO:00023661260.308
regulation of inflammatory response to antigenic stimulusGO:0002861210.307
positive regulation of apoptotic cell clearanceGO:200042730.307
b cell activation involved in immune responseGO:0002312500.304
metal ion homeostasisGO:00550651890.304
drug catabolic processGO:004273720.300
positive regulation of fever generationGO:003162260.299
regulation of heat generationGO:003165080.299
positive regulation of t cell activationGO:00508701010.299
cellular response to organic cyclic compoundGO:0071407870.298
pattern recognition receptor signaling pathwayGO:0002221470.297
positive regulation of protein localization to nucleusGO:1900182300.295
cellular response to peptideGO:1901653920.294
regulation of kinase activityGO:00435492490.294
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.293
regulation of protein localizationGO:00328802310.292
Human
cell chemotaxisGO:0060326810.289
regulation of natural killer cell mediated cytotoxicityGO:0042269190.288
positive regulation of cytosolic calcium ion concentrationGO:0007204650.287
icosanoid metabolic processGO:0006690330.287
negative regulation of interleukin 5 productionGO:003271440.286
leukocyte migrationGO:00509001240.285
lateral line system developmentGO:004892510.285
response to molecule of fungal originGO:000223840.283
positive regulation of map kinase activityGO:0043406840.282
response to amino acidGO:0043200370.278
interleukin 13 secretionGO:007261120.276
modulation by symbiont of defense related host nitric oxide productionGO:005216310.275
isotype switching to igg isotypesGO:0048291100.274
immunoglobulin productionGO:0002377730.274
Human
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.271
Human
leukocyte proliferationGO:00706611720.271
Human
hepatocyte growth factor receptor signaling pathwayGO:004801230.270
regulation of t helper cell differentiationGO:0045622140.270
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.269
positive regulation of protein phosphorylationGO:00019342420.268
Human
positive regulation of chemokine biosynthetic processGO:004508060.267
calcium ion homeostasisGO:00550741270.267
regulation of interleukin 6 productionGO:0032675550.267
Human
production of molecular mediator involved in inflammatory responseGO:0002532210.267
dna metabolic processGO:00062593030.263
leukocyte apoptotic processGO:0071887710.263
sterol metabolic processGO:0016125580.261
positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181220.260
negative regulation of muscle contractionGO:0045932120.260
temperature homeostasisGO:0001659260.259
regulation of tyrosine phosphorylation of stat1 proteinGO:004251020.257
heat generationGO:0031649130.255
chemokine metabolic processGO:0050755100.254
cellular homeostasisGO:00197252400.254
response to organonitrogen compoundGO:00102432460.254
Human
negative regulation of hydrolase activityGO:0051346710.253
b cell proliferationGO:0042100530.252
somatic cell dna recombinationGO:0016444510.252
positive regulation of t helper 1 cell cytokine productionGO:200055610.249
immune response regulating cell surface receptor signaling pathwayGO:0002768800.247
neuron deathGO:00709971540.247
response to interleukin 18GO:007067340.243
blood vessel morphogenesisGO:00485142850.240
regulation of neutrophil mediated killing of symbiont cellGO:007094920.240
cellular divalent inorganic cation homeostasisGO:00725031270.239
regulation of membrane potentialGO:00423911920.238
lymphocyte homeostasisGO:0002260640.238
t helper 1 type immune responseGO:0042088250.238
positive regulation of tyrosine phosphorylation of stat1 proteinGO:004251110.238
positive regulation of intracellular transportGO:0032388700.236
lymphocyte differentiationGO:00300982420.236
somatic diversification of immunoglobulinsGO:0016445430.235
negative regulation of immune system processGO:00026832090.234
lymphocyte activation involved in immune responseGO:0002285930.233
dendritic cell dendrite assemblyGO:009702620.231
apoptotic signaling pathwayGO:00971903060.231
nitrogen compound transportGO:00717052710.229
negative regulation of odontogenesis of dentin containing toothGO:004248910.227
neutrophil mediated killing of bacteriumGO:007094460.223
leukocyte mediated cytotoxicityGO:0001909620.223
positive regulation of cell killingGO:0031343330.222
t cell proliferationGO:00420981200.220
Human
positive regulation of natural killer cell chemotaxisGO:200050310.219
t cell differentiationGO:00302171740.219
modification of morphology or physiology of other organismGO:0035821180.219
negative regulation of t helper 1 type immune responseGO:000282650.219
positive regulation of cell deathGO:00109422240.219
Human
negative regulation of leukocyte proliferationGO:0070664460.217
regulation of defense response to bacteriumGO:190042430.216
positive regulation of brown fat cell differentiationGO:009033640.214
acute inflammatory responseGO:0002526410.213
Human
negative regulation of alpha beta t cell activationGO:0046636180.211
positive regulation of neutrophil mediated killing of fungusGO:007096510.209
negative regulation of lymphocyte activationGO:0051250910.207
response to interleukin 15GO:007067230.206
positive regulation of protein modification processGO:00314012990.206
Human
positive regulation of membrane protein ectodomain proteolysisGO:005104430.205
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007043010.204
negative regulation of intracellular signal transductionGO:19025321670.203
positive regulation of synaptic plasticityGO:003191540.203
regulation of interferon gamma productionGO:0032649570.202
regulation of t cell activationGO:00508631700.202
positive regulation of hematopoietic stem cell proliferationGO:190203520.201
chronic inflammatory responseGO:000254490.200
neutrophil migrationGO:1990266370.198
positive regulation of innate immune responseGO:0045089800.197
response to inorganic substanceGO:0010035960.194
Human
positive regulation of activated t cell proliferationGO:004210480.194
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.192
regulation of chronic inflammatory responseGO:000267670.192
regulation of myotube differentiationGO:0010830620.192
type i interferon signaling pathwayGO:0060337100.191
protein kinase b signalingGO:0043491740.191
regulation of peptide transportGO:0090087910.189
muscle cell differentiationGO:00426922610.186
positive regulation of cytokine secretionGO:0050715410.186
fatty acid metabolic processGO:00066311210.186
regulation of alpha beta t cell proliferationGO:0046640180.185
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.183
response to corticosteroidGO:0031960200.183
Human
negative regulation of t cell proliferationGO:0042130380.182
cation homeostasisGO:00550802120.182
anion transportGO:00068201770.180
positive regulation of programmed cell deathGO:00430682180.179
Human
divalent metal ion transportGO:00708381720.178
response to steroid hormoneGO:0048545560.178
Human
regulation of fatty acid transportGO:2000191100.178
negative regulation of b cell proliferationGO:0030889130.175
regulation of t helper 1 cell cytokine productionGO:200055410.175
cellular response to tumor necrosis factorGO:0071356210.175
natural killer cell mediated immunityGO:0002228290.174
defense response to virusGO:0051607680.174
Human
positive regulation of neuron differentiationGO:00456661410.174
interleukin 6 productionGO:0032635580.174
Human
regulation of membrane protein ectodomain proteolysisGO:005104330.173
positive regulation of chemotaxisGO:0050921380.173
positive regulation of production of molecular mediator of immune responseGO:0002702450.172
Human
positive regulation of chronic inflammatory responseGO:000267840.171
regulation of interleukin 5 secretionGO:200066220.171
transmembrane transportGO:00550854120.171
regulation of neuron apoptotic processGO:00435231220.169
icosanoid secretionGO:0032309120.168
positive regulation of isotype switchingGO:0045830150.168
humoral immune responseGO:0006959570.167
prostaglandin transportGO:001573270.166
negative regulation of t cell activationGO:0050868650.166
positive regulation of b cell activationGO:0050871490.166
Human
positive regulation of leukocyte differentiationGO:1902107860.165
cd4 positive alpha beta t cell differentiationGO:0043367410.164
keratinocyte migrationGO:005154630.163
positive regulation of immunoglobulin productionGO:0002639280.162
Human
organ regenerationGO:003110020.161
interferon beta biosynthetic processGO:004535040.161
positive regulation of transcription factor import into nucleusGO:004299380.160
positive regulation of dna recombinationGO:0045911170.159
negative regulation of syncytium formation by plasma membrane fusionGO:003424250.159
positive regulation of interleukin 6 productionGO:0032755370.157
Human
cytokine secretionGO:0050663720.157
protein import into nucleusGO:0006606950.156
type 2 immune responseGO:0042092230.156
positive regulation of cell developmentGO:00107202370.155
cholesterol metabolic processGO:0008203560.154
positive regulation of isotype switching to ige isotypesGO:004829540.154
drug metabolic processGO:001714440.153
positive regulation of monocyte chemotaxisGO:009002620.152
positive regulation of muscle cell differentiationGO:0051149390.152
regulation of protein kinase activityGO:00458592320.151
synaptic transmissionGO:00072683290.151
positive regulation of b cell proliferationGO:0030890240.151
neutrophil chemotaxisGO:0030593360.150
response to peptide hormoneGO:00434341270.150
fibroblast growth factor productionGO:009026940.150
cdc42 protein signal transductionGO:003248800.149
response to drugGO:0042493750.149
positive regulation of jak stat cascadeGO:0046427220.149
Human
positive regulation of syncytium formation by plasma membrane fusionGO:0060143170.148
interleukin 2 productionGO:0032623330.147
regulation of hematopoietic stem cell proliferationGO:190203330.146
muscle tissue developmentGO:00605373080.146
regulation of natural killer cell differentiationGO:0032823110.146
positive regulation of acute inflammatory responseGO:0002675160.145
Human
positive regulation of b cell chemotaxisGO:200053820.145
cytokine production involved in immune responseGO:0002367340.143
t helper cell differentiationGO:0042093280.143
positive regulation of type 2 immune responseGO:000283090.141
response to peptideGO:19016521360.140
leukocyte chemotaxisGO:0030595690.139
mammary gland lobule developmentGO:0061377220.138
positive regulation of neuron apoptotic processGO:0043525250.138
regulation of neuron deathGO:19012141340.138
activation of mapk activityGO:0000187590.137
modulation by symbiont of host immune responseGO:005255310.137
prostaglandin metabolic processGO:0006693110.136
amino acid transportGO:0006865610.135
innate immune response activating cell surface receptor signaling pathwayGO:000222040.135
transcription factor import into nucleusGO:0042991260.135
regulation of secretion by cellGO:19035302490.135
negative regulation of cellular protein metabolic processGO:00322692470.134
nitric oxide biosynthetic processGO:0006809250.134
cellular response to interleukin 1GO:007134780.133
regulation of eosinophil migrationGO:200041620.132
regulation of fibroblast growth factor productionGO:009027040.131
positive regulation of protein transportGO:0051222930.131
Human
positive regulation of immune complex clearance by monocytes and macrophagesGO:009026520.130
positive regulation of cytoplasmic transportGO:1903651400.130
regulation of isotype switching to igg isotypesGO:0048302100.130
muscle system processGO:00030121410.129
positive regulation of nitric oxide biosynthetic processGO:0045429140.128
regulation of skeletal muscle fiber developmentGO:0048742360.128
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.127
morphogenesis of a branching structureGO:00017632030.127
protein targetingGO:00066051430.126
cytokine secretion involved in immune responseGO:000237460.126
tyrosine phosphorylation of stat3 proteinGO:0042503120.126
Human
angiogenesisGO:00015252010.125
positive regulation of interleukin 1 secretionGO:0050716140.125
regulation of intracellular transportGO:00323861590.124
negative regulation of defense responseGO:0031348770.123
antibiotic transportGO:004289110.123
regulation of cellular catabolic processGO:00313292420.122
cellular response to inorganic substanceGO:0071241370.120
macromolecule catabolic processGO:00090572810.120
regulation of sequence specific dna binding transcription factor activityGO:00510901060.119
Human
t cell activation involved in immune responseGO:0002286430.119
muscle cell developmentGO:00550011330.119
mast cell proliferationGO:007066240.119
regulation of cytoplasmic transportGO:19036491120.118
organic acid transportGO:00158491010.118
negative regulation of protein processingGO:0010955790.118
tumor necrosis factor mediated signaling pathwayGO:0033209130.117
cellular ion homeostasisGO:00068731650.116
positive regulation of interleukin 18 productionGO:003274120.116
regulation of muscle tissue developmentGO:1901861970.115
interleukin 1 mediated signaling pathwayGO:007049840.115
regulation of production of molecular mediator of immune responseGO:0002700650.114
Human
syncytium formation by plasma membrane fusionGO:0000768420.114
granulocyte migrationGO:0097530430.113
carbohydrate homeostasisGO:00335001280.113
regulation of interleukin 13 secretionGO:200066520.113
positive regulation of mitotic cell cycleGO:0045931410.112
cellular response to arsenic containing substanceGO:007124340.112
organic hydroxy compound metabolic processGO:19016152030.111
cation transportGO:00068123990.111
jak stat cascade involved in growth hormone signaling pathwayGO:006039740.110
protein localization to nucleusGO:00345041210.109
negative regulation of cellular amine metabolic processGO:003323910.108
negative regulation of adaptive immune responseGO:0002820250.108
glucose homeostasisGO:00425931280.108
t helper 1 cell cytokine productionGO:003574410.108
regulation of natural killer cell proliferationGO:003281720.108
negative regulation of response to woundingGO:1903035770.107
positive regulation of myoblast differentiationGO:004566380.106
negative regulation of chronic inflammatory responseGO:000267730.106
striated muscle tissue developmentGO:00147062930.105
positive regulation of dendritic cell dendrite assemblyGO:200054910.105
regulation of t helper 1 type immune responseGO:0002825170.105
negative regulation of t helper 2 cell differentiationGO:004562940.105
cell surface pattern recognition receptor signaling pathwayGO:000275220.104
regulation of organic acid transportGO:0032890160.104
nuclear transportGO:00511691390.104
protein importGO:00170381010.104
g protein coupled receptor signaling pathway coupled to cgmp nucleotide second messengerGO:000719910.104
response to interleukin 6GO:0070741100.103
positive regulation of cytokine secretion involved in immune responseGO:000274120.103
negative regulation of macrophage apoptotic processGO:200011030.103
regulation of lipopolysaccharide mediated signaling pathwayGO:003166490.102
negative regulation of cellular amino acid metabolic processGO:004576300.102
positive regulation of organic acid transportGO:0032892110.102
negative regulation of homeostatic processGO:0032845710.102
positive regulation of chemokine secretionGO:009019740.102
response to low density lipoprotein particleGO:005509820.102
regulation of fever generation by regulation of prostaglandin secretionGO:007181020.101
l amino acid transportGO:0015807320.101
cytoplasmic transportGO:00164822340.101
regulation of response to cytokine stimulusGO:0060759230.100
positive regulation of cell migrationGO:00303351090.100
cytosolic calcium ion homeostasisGO:0051480700.100
positive regulation of protein catabolic processGO:0045732600.099
epidermis developmentGO:00085441870.099
regulation of immunoglobulin secretionGO:0051023120.099
Human
regulation of vasculature developmentGO:1901342880.099
regulation of neutrophil mediated killing of bacteriumGO:007095010.099
antimicrobial peptide biosynthetic processGO:000277720.099

Il6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.279
Human
disease of cellular proliferationDOID:1456600.279
Human
organ system cancerDOID:005068600.279
Human