Mus musculus

44 known processes

Leo1

Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

(Aliases: Gm185,MGC100232,MGC102277)

Leo1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amine metabolic processGO:0009308450.107
protein alkylationGO:0008213810.098
chromatin organizationGO:00063252060.095
regulation of cellular amine metabolic processGO:0033238200.091
cellular amino acid metabolic processGO:00065201030.077
dna metabolic processGO:00062593030.076
regulation of cellular amino acid metabolic processGO:000652150.075
cellular ketone metabolic processGO:0042180840.070
regulation of histone h3 k4 methylationGO:0051569120.070
peptidyl amino acid modificationGO:00181933360.068
regulation of chromosome organizationGO:0033044830.066
protein methylationGO:0006479810.062
regulation of cellular ketone metabolic processGO:0010565660.062
positive regulation of cellular amine metabolic processGO:003324050.061
methylationGO:00322591340.057
regulation of chromatin modificationGO:1903308570.056
histone lysine methylationGO:0034968500.055
positive regulation of organelle organizationGO:00106381280.052
positive regulation of chromatin modificationGO:1903310280.051
positive regulation of protein modification processGO:00314012990.050
cellular response to dna damage stimulusGO:00069742070.049
stem cell differentiationGO:00488632680.049
myeloid cell differentiationGO:00300992330.044
cellular response to biotic stimulusGO:0071216920.044
stem cell developmentGO:00488642190.044
regulation of histone methylationGO:0031060300.043
negative regulation of immune system processGO:00026832090.041
positive regulation of cellular amino acid metabolic processGO:004576430.041
covalent chromatin modificationGO:00165691630.039
histone modificationGO:00165701590.039
regulation of organelle organizationGO:00330432890.038
positive regulation of histone modificationGO:0031058280.038
digestive tract developmentGO:00485651900.038
cellular amine metabolic processGO:0044106440.037
cellular response to lipidGO:00713961450.036
positive regulation of dna templated transcription elongationGO:003278620.034
regulation of chromatin organizationGO:1902275570.034
response to lipopolysaccharideGO:00324961280.034
cellular response to molecule of bacterial originGO:0071219830.033
regulation of histone modificationGO:0031056560.033
regulation of myeloid cell differentiationGO:0045637960.032
negative regulation of myeloid cell differentiationGO:0045638380.030
blastocyst developmentGO:0001824800.030
digestive tract morphogenesisGO:00485461470.029
macromolecule methylationGO:00434141200.028
histone h3 k4 methylationGO:0051568230.028
cellular response to cytokine stimulusGO:00713451890.027
digestive system developmentGO:00551232000.027
chromatin modificationGO:00165681870.025
mrna metabolic processGO:0016071840.024
histone methylationGO:0016571710.024
peptidyl lysine modificationGO:0018205770.024
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.024
glycosyl compound catabolic processGO:19016582060.024
cellular response to lipopolysaccharideGO:0071222770.023
purine nucleotide metabolic processGO:00061633020.023
regulation of cell cycleGO:00517262810.023
microtubule based processGO:00070172360.023
negative regulation of cell cycleGO:00457861230.023
positive regulation of histone h3 k4 methylationGO:005157150.023
nucleoside triphosphate catabolic processGO:00091432050.022
response to molecule of bacterial originGO:00022371430.022
male gamete generationGO:00482322850.022
muscle tissue developmentGO:00605373080.022
positive regulation of histone methylationGO:0031062160.021
organonitrogen compound catabolic processGO:19015652640.021
cell adhesionGO:00071553290.021
carbohydrate derivative catabolic processGO:19011362310.021
negative regulation of molecular functionGO:00440922580.021
cell activation involved in immune responseGO:00022631260.020
apoptotic signaling pathwayGO:00971903060.020
negative regulation of cell proliferationGO:00082852960.020
g1 s transition of mitotic cell cycleGO:0000082570.020
nucleoside phosphate metabolic processGO:00067533380.020
lymphocyte activation involved in immune responseGO:0002285930.019
glycosyl compound metabolic processGO:19016572460.019
ribose phosphate metabolic processGO:00196932910.019
immune effector processGO:00022523210.019
nucleoside phosphate catabolic processGO:19012922220.019
regulation of cellular component biogenesisGO:00440871810.019
regulation of bindingGO:00510981110.019
positive regulation of nervous system developmentGO:00519622210.019
nucleobase containing small molecule metabolic processGO:00550863520.019
transmembrane transportGO:00550854120.019
organelle fissionGO:00482851700.018
nucleotide metabolic processGO:00091173320.018
purine containing compound metabolic processGO:00725213110.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.018
cytokine mediated signaling pathwayGO:00192211150.018
purine nucleoside triphosphate metabolic processGO:00091442260.018
purine ribonucleoside catabolic processGO:00461302050.018
positive regulation of protein phosphorylationGO:00019342420.018
ribonucleotide catabolic processGO:00092612080.018
regulation of cell cycle processGO:00105641600.018
purine ribonucleotide catabolic processGO:00091542080.017
nucleoside triphosphate metabolic processGO:00091412300.017
mrna processingGO:0006397630.017
ribonucleoside triphosphate catabolic processGO:00092031990.017
ribonucleoside metabolic processGO:00091192450.017
purine nucleoside triphosphate catabolic processGO:00091462030.017
cell fate commitmentGO:00451652100.017
germ cell developmentGO:00072811850.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
negative regulation of cell cycle processGO:0010948690.017
ribonucleoside catabolic processGO:00424542060.016
nuclear divisionGO:00002801580.016
purine nucleoside catabolic processGO:00061522050.016
dna repairGO:00062811070.016
peptidyl lysine methylationGO:0018022290.016
nucleoside metabolic processGO:00091162460.016
nucleotide catabolic processGO:00091662170.016
posttranscriptional regulation of gene expressionGO:00106081550.016
leukocyte mediated immunityGO:00024431740.016
negative regulation of intracellular signal transductionGO:19025321670.016
stem cell maintenanceGO:00198271300.016
small gtpase mediated signal transductionGO:0007264970.016
regulation of cell activationGO:00508652890.016
purine nucleotide catabolic processGO:00061952110.016
negative regulation of dna replicationGO:000815640.016
cellular nitrogen compound catabolic processGO:00442702800.015
mitotic cell cycle processGO:19030471590.015
leukocyte differentiationGO:00025213420.015
intracellular protein transportGO:00068862040.015
striated muscle tissue developmentGO:00147062930.015
homeostasis of number of cellsGO:00488722100.015
purine ribonucleoside metabolic processGO:00461282410.015
cell type specific apoptotic processGO:00972852680.015
ribonucleotide metabolic processGO:00092592910.015
organophosphate catabolic processGO:00464342320.015
mitotic cell cycleGO:00002781950.015
purine ribonucleoside triphosphate catabolic processGO:00092071990.015
ribonucleoside triphosphate metabolic processGO:00091992200.015
purine ribonucleotide metabolic processGO:00091502900.015
macromolecule catabolic processGO:00090572810.015
cytoplasmic transportGO:00164822340.015
regulation of synaptic growth at neuromuscular junctionGO:000858240.015
nitrogen compound transportGO:00717052710.014
formation of primary germ layerGO:0001704770.014
purine nucleoside metabolic processGO:00422782410.014
protein modification by small protein conjugation or removalGO:00706472070.014
protein localization to organelleGO:00333651850.014
cation transportGO:00068123990.014
regulation of histone h3 k36 methylationGO:000041410.014
protein ubiquitinationGO:00165671710.014
skeletal system developmentGO:00015013560.014
muscle cell differentiationGO:00426922610.014
hematopoietic progenitor cell differentiationGO:00022441430.014
adaptive immune responseGO:00022501550.014
regulation of cellular response to stressGO:00801351590.014
heterocycle catabolic processGO:00467002800.014
regulation of mitotic cell cycleGO:00073461260.013
atp metabolic processGO:0046034750.013
rna processingGO:00063961050.013
regulation of apoptotic signaling pathwayGO:20012331970.013
lymphocyte differentiationGO:00300982420.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
aromatic compound catabolic processGO:00194392860.013
gliogenesisGO:00420631410.013
spermatogenesisGO:00072832840.013
protein catabolic processGO:00301632210.013
negative regulation of cellular amine metabolic processGO:003323910.013
regulation of lymphocyte activationGO:00512492400.013
gonad developmentGO:00084061410.013
membrane organizationGO:00610242450.013
production of molecular mediator of immune responseGO:00024401030.012
cellular response to hormone stimulusGO:00328701500.012
purine containing compound catabolic processGO:00725232130.012
positive regulation of cell deathGO:00109422240.012
lymphocyte mediated immunityGO:00024491390.012
negative regulation of phosphorylationGO:00423261660.012
regulation of neuron differentiationGO:00456642810.012
transmission of nerve impulseGO:0019226760.012
regulation of protein complex assemblyGO:0043254830.012
dna replicationGO:0006260520.012
skeletal muscle organ developmentGO:00605381630.012
positive regulation of cell developmentGO:00107202370.012
regulation of cell projection organizationGO:00313442060.012
wnt signaling pathwayGO:00160551880.012
epithelial cell proliferationGO:00506731740.012
positive regulation of chromosome organizationGO:2001252330.012
positive regulation of programmed cell deathGO:00430682180.012
positive regulation of cell activationGO:00508671580.012
response to radiationGO:00093141650.012
endodermal cell fate commitmentGO:0001711120.012
nucleoside catabolic processGO:00091642060.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
cytokine productionGO:00018163190.011
blastocyst growthGO:0001832230.011
regulation of defense responseGO:00313472330.011
renal system developmentGO:00720012250.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
ion transmembrane transportGO:00342203610.011
organic cyclic compound catabolic processGO:19013612950.011
gastrulationGO:00073691160.011
regulation of cell migrationGO:00303342190.011
b cell activationGO:00421131610.011
inorganic cation transmembrane transportGO:00986622070.011
neuronal action potentialGO:0019228540.011
negative regulation of cellular protein metabolic processGO:00322692470.011
peptidyl lysine trimethylationGO:0018023120.011
negative regulation of cellular component organizationGO:00511291940.011
response to light stimulusGO:00094161350.011
negative regulation of protein modification processGO:00314001630.011
cation transmembrane transportGO:00986552660.011
multicellular organismal homeostasisGO:00488711640.011
ras protein signal transductionGO:0007265770.011
protein modification by small protein conjugationGO:00324461870.011
blood vessel morphogenesisGO:00485142850.011
skeletal system morphogenesisGO:00487052030.011
regulation of protein localizationGO:00328802310.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
multicellular organismal signalingGO:0035637910.011
maintenance of locationGO:0051235890.011
meiotic cell cycleGO:00513211220.011
t cell activationGO:00421102890.011
immunoglobulin mediated immune responseGO:0016064690.010
cell cycle g1 s phase transitionGO:0044843570.010
negative regulation of cellular amino acid metabolic processGO:004576300.010
dna templated transcription elongationGO:0006354130.010
regulation of cell motilityGO:20001452360.010
establishment of protein localization to organelleGO:00725941180.010
mapk cascadeGO:00001652810.010
fertilizationGO:00095661270.010
forebrain developmentGO:00309003020.010
spermatid developmentGO:00072861080.010
protein targetingGO:00066051430.010
nucleoside monophosphate metabolic processGO:0009123850.010
carbohydrate metabolic processGO:00059752300.010
regulation of anatomical structure sizeGO:00900661780.010
nucleocytoplasmic transportGO:00069131390.010

Leo1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.043
cancerDOID:16200.043
organ system cancerDOID:005068600.036
disease of anatomical entityDOID:700.020
nervous system diseaseDOID:86300.020
immune system diseaseDOID:291400.011
musculoskeletal system diseaseDOID:1700.011