IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Ddx54

DEAD (Asp-Glu-Ala-Asp) box polypeptide 54

(Aliases: DP97,2410015A15Rik,AI414901)

Entrez: 71990
Ensembl: ENSMUSG00000029599
UniProtKB: Q8K4L0

Process Predictions
Disease Predictions

Ddx54 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular amino acid metabolic process	GO:0006520	103	0.148
maintenance of location	GO:0051235	89	0.103
nucleoside phosphate metabolic process	GO:0006753	338	0.103	Human
nucleotide metabolic process	GO:0009117	332	0.084	Human
translation	GO:0006412	93	0.082
amine metabolic process	GO:0009308	45	0.073
nucleoside metabolic process	GO:0009116	246	0.073	Human
cytoplasmic translational initiation	GO:0002183	3	0.063
t cell differentiation	GO:0030217	174	0.061
cellular amine metabolic process	GO:0044106	44	0.059
purine ribonucleotide metabolic process	GO:0009150	290	0.059	Human
nucleoside triphosphate catabolic process	GO:0009143	205	0.056	Human
translational initiation	GO:0006413	24	0.055
ribonucleoprotein complex subunit organization	GO:0071826	28	0.055	Yeast
peptidyl amino acid modification	GO:0018193	336	0.055
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.053
purine containing compound metabolic process	GO:0072521	311	0.053	Human
purine nucleotide catabolic process	GO:0006195	211	0.048	Human
glycosyl compound metabolic process	GO:1901657	246	0.048	Human
regulation of cellular ketone metabolic process	GO:0010565	66	0.048
leukocyte differentiation	GO:0002521	342	0.048
purine nucleoside catabolic process	GO:0006152	205	0.047	Human
rhythmic process	GO:0048511	174	0.047
purine nucleoside metabolic process	GO:0042278	241	0.046	Human
transmembrane transport	GO:0055085	412	0.045
cellular ketone metabolic process	GO:0042180	84	0.045
negative regulation of cellular amine metabolic process	GO:0033239	1	0.043
negative regulation of intracellular signal transduction	GO:1902532	167	0.042
lymphocyte differentiation	GO:0030098	242	0.041
purine nucleotide metabolic process	GO:0006163	302	0.038	Human
innate immune response	GO:0045087	157	0.038
cellular metal ion homeostasis	GO:0006875	151	0.038
cleavage involved in rrna processing	GO:0000469	1	0.038
nucleoside triphosphate metabolic process	GO:0009141	230	0.037	Human
cellular response to cytokine stimulus	GO:0071345	189	0.037
generation of precursor metabolites and energy	GO:0006091	103	0.037
t cell differentiation in thymus	GO:0033077	77	0.036
negative regulation of molecular function	GO:0044092	258	0.036
ribose phosphate metabolic process	GO:0019693	291	0.036	Human
response to organonitrogen compound	GO:0010243	246	0.035
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.035	Human
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.034	Human
posttranscriptional regulation of gene expression	GO:0010608	155	0.034
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.034
regulation of cellular amine metabolic process	GO:0033238	20	0.031
gonad development	GO:0008406	141	0.031
regulation of t cell differentiation	GO:0045580	83	0.030
endocytosis	GO:0006897	168	0.030
cellular homeostasis	GO:0019725	240	0.030
negative regulation of protein phosphorylation	GO:0001933	126	0.030
development of primary sexual characteristics	GO:0045137	143	0.030
cation homeostasis	GO:0055080	212	0.029
trna metabolic process	GO:0006399	11	0.029
ribonucleoside metabolic process	GO:0009119	245	0.028	Human
dna dealkylation	GO:0035510	11	0.028
t cell activation	GO:0042110	289	0.028
regulation of t cell activation	GO:0050863	170	0.028
carbohydrate derivative catabolic process	GO:1901136	231	0.028	Human
mrna metabolic process	GO:0016071	84	0.027
transcription coupled nucleotide excision repair	GO:0006283	2	0.026
metal ion homeostasis	GO:0055065	189	0.026
maturation of ssu rrna	GO:0030490	1	0.026
ossification	GO:0001503	216	0.026
amino acid activation	GO:0043038	1	0.026
ion transmembrane transport	GO:0034220	361	0.026
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.026	Human
negative regulation of mapk cascade	GO:0043409	65	0.026
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.026	Human
carbohydrate derivative biosynthetic process	GO:1901137	183	0.025
response to oxidative stress	GO:0006979	123	0.025
positive regulation of cellular amine metabolic process	GO:0033240	5	0.025
ribonucleotide catabolic process	GO:0009261	208	0.025	Human
oxidation reduction process	GO:0055114	342	0.024
epithelial tube morphogenesis	GO:0060562	303	0.024
negative regulation of phosphorus metabolic process	GO:0010563	184	0.024
response to acid chemical	GO:0001101	111	0.024
cell adhesion	GO:0007155	329	0.024
dephosphorylation	GO:0016311	129	0.023
regulation of myeloid cell differentiation	GO:0045637	96	0.023
negative regulation of phosphorylation	GO:0042326	166	0.023
immune response activating signal transduction	GO:0002757	116	0.023
negative regulation of protein metabolic process	GO:0051248	282	0.022
regulation of intracellular transport	GO:0032386	159	0.022
regulation of cell activation	GO:0050865	289	0.021
divalent inorganic cation homeostasis	GO:0072507	138	0.021
negative regulation of phosphate metabolic process	GO:0045936	184	0.021
organophosphate biosynthetic process	GO:0090407	122	0.021
aromatic compound catabolic process	GO:0019439	286	0.021	Human
chemotaxis	GO:0006935	247	0.021
regulation of lymphocyte activation	GO:0051249	240	0.021
regulation of lymphocyte differentiation	GO:0045619	107	0.021
purine ribonucleoside metabolic process	GO:0046128	241	0.021	Human
cation transport	GO:0006812	399	0.021
regulation of defense response	GO:0031347	233	0.020
myeloid leukocyte differentiation	GO:0002573	119	0.020
myeloid cell differentiation	GO:0030099	233	0.020
mrna processing	GO:0006397	63	0.020
nucleic acid phosphodiester bond hydrolysis	GO:0090305	49	0.020
peptidyl tyrosine modification	GO:0018212	145	0.019
organic cyclic compound catabolic process	GO:1901361	295	0.019	Human
divalent inorganic cation transport	GO:0072511	178	0.019
regulation of nucleotide metabolic process	GO:0006140	169	0.019
regulation of membrane potential	GO:0042391	192	0.018
regulation of mrna splicing via spliceosome	GO:0048024	32	0.018
small gtpase mediated signal transduction	GO:0007264	97	0.018
embryonic organ morphogenesis	GO:0048562	276	0.018
regulation of t cell differentiation in thymus	GO:0033081	24	0.018
glycosyl compound catabolic process	GO:1901658	206	0.018	Human
cellular response to organonitrogen compound	GO:0071417	145	0.018
purine ribonucleotide catabolic process	GO:0009154	208	0.017	Human
regulation of homeostatic process	GO:0032844	182	0.017
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000463	1	0.017	Yeast
multicellular organismal homeostasis	GO:0048871	164	0.017
regulation of neuron projection development	GO:0010975	169	0.017
myeloid cell homeostasis	GO:0002262	114	0.017
positive regulation of nucleotide metabolic process	GO:0045981	114	0.017
nucleoside monophosphate catabolic process	GO:0009125	59	0.017	Human
reactive oxygen species metabolic process	GO:0072593	84	0.016
sensory perception	GO:0007600	245	0.016
atp metabolic process	GO:0046034	75	0.016	Human
negative regulation of protein modification process	GO:0031400	163	0.016
response to peptide	GO:1901652	136	0.016
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.016
rna phosphodiester bond hydrolysis	GO:0090501	19	0.016
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.016
gland development	GO:0048732	330	0.016
immune response regulating cell surface receptor signaling pathway	GO:0002768	80	0.016
ribonucleotide metabolic process	GO:0009259	291	0.016	Human
positive regulation of growth	GO:0045927	104	0.016
cellular carbohydrate metabolic process	GO:0044262	119	0.016
inflammatory response	GO:0006954	244	0.015
divalent metal ion transport	GO:0070838	172	0.015
mapk cascade	GO:0000165	281	0.015
negative regulation of cellular protein metabolic process	GO:0032269	247	0.015
regulation of cellular amino acid metabolic process	GO:0006521	5	0.015
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.015
regulation of cytoplasmic transport	GO:1903649	112	0.015
regulation of cell cycle	GO:0051726	281	0.015
nucleotide biosynthetic process	GO:0009165	78	0.015
response to starvation	GO:0042594	65	0.015
sequestering of calcium ion	GO:0051208	18	0.015
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.015	Human
neuron death	GO:0070997	154	0.015
ovarian follicle development	GO:0001541	40	0.015
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000466	1	0.015	Yeast
cellular response to dna damage stimulus	GO:0006974	207	0.015
negative regulation of kinase activity	GO:0033673	81	0.014
nucleoside phosphate catabolic process	GO:1901292	222	0.014	Human
calcium ion homeostasis	GO:0055074	127	0.014
cellular response to external stimulus	GO:0071496	88	0.014
actin cytoskeleton organization	GO:0030036	220	0.014
adult behavior	GO:0030534	135	0.014
organonitrogen compound catabolic process	GO:1901565	264	0.014	Human
regulation of ion transport	GO:0043269	215	0.014
negative regulation of transferase activity	GO:0051348	85	0.014
endonucleolytic cleavage involved in rrna processing	GO:0000478	1	0.014
purine nucleotide biosynthetic process	GO:0006164	65	0.014
nucleobase containing small molecule metabolic process	GO:0055086	352	0.014	Human
spermatid development	GO:0007286	108	0.014
retina development in camera type eye	GO:0060041	119	0.014
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.014	Human
protein modification by small protein conjugation or removal	GO:0070647	207	0.014
ncrna processing	GO:0034470	26	0.014	Yeast
nucleoside phosphate biosynthetic process	GO:1901293	79	0.014
germ cell development	GO:0007281	185	0.014
activation of immune response	GO:0002253	138	0.013
cytokine production	GO:0001816	319	0.013
nucleoside monophosphate metabolic process	GO:0009123	85	0.013	Human
tissue homeostasis	GO:0001894	115	0.013
regulation of protein localization	GO:0032880	231	0.013
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.013	Human
t cell selection	GO:0045058	34	0.013
cellular response to extracellular stimulus	GO:0031668	81	0.013
immune effector process	GO:0002252	321	0.013
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.013
peptidyl tyrosine phosphorylation	GO:0018108	143	0.013
maturation of lsu rrna	GO:0000470	1	0.013	Yeast
stem cell differentiation	GO:0048863	268	0.013
spermatid differentiation	GO:0048515	115	0.013
camera type eye development	GO:0043010	266	0.013
positive regulation of protein modification process	GO:0031401	299	0.013
cellular response to lipid	GO:0071396	145	0.013
sequestering of metal ion	GO:0051238	19	0.012
positive regulation of cytokine production	GO:0001819	174	0.012
intracellular protein transport	GO:0006886	204	0.012
mitochondrion organization	GO:0007005	134	0.012
cell activation involved in immune response	GO:0002263	126	0.012
response to nutrient levels	GO:0031667	109	0.012
regulation of purine nucleotide metabolic process	GO:1900542	169	0.012
epidermis development	GO:0008544	187	0.012
response to light stimulus	GO:0009416	135	0.012
positive regulation of protein phosphorylation	GO:0001934	242	0.012
organelle localization	GO:0051640	179	0.012
ribonucleotide biosynthetic process	GO:0009260	59	0.012
negative regulation of neuron apoptotic process	GO:0043524	92	0.012
positive regulation of cell death	GO:0010942	224	0.012
regulation of establishment of protein localization	GO:0070201	181	0.012
mitotic cell cycle	GO:0000278	195	0.012
nuclear transport	GO:0051169	139	0.012
purine ribonucleotide biosynthetic process	GO:0009152	59	0.012
trna aminoacylation for protein translation	GO:0006418	1	0.012
cellular response to acid chemical	GO:0071229	68	0.012
regulation of neuron death	GO:1901214	134	0.012
positive regulation of hydrolase activity	GO:0051345	148	0.012
regulation of feeding behavior	GO:0060259	3	0.012
regulation of cell migration	GO:0030334	219	0.012
dna metabolic process	GO:0006259	303	0.011
rho protein signal transduction	GO:0007266	32	0.011
transmission of nerve impulse	GO:0019226	76	0.011
immune response regulating signaling pathway	GO:0002764	125	0.011
regulation of protein transport	GO:0051223	163	0.011
hexose metabolic process	GO:0019318	98	0.011
protein dna complex subunit organization	GO:0071824	28	0.011
rna interference	GO:0016246	2	0.011
positive regulation of programmed cell death	GO:0043068	218	0.011
b cell activation	GO:0042113	161	0.011
purine ribonucleoside catabolic process	GO:0046130	205	0.011	Human
spermatogenesis	GO:0007283	284	0.011
regulation of rna splicing	GO:0043484	37	0.011
g protein coupled receptor signaling pathway	GO:0007186	243	0.011
regulation of transmembrane transport	GO:0034762	128	0.011
blastocyst development	GO:0001824	80	0.011
tissue remodeling	GO:0048771	102	0.011
embryonic placenta development	GO:0001892	98	0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	43	0.011
cellular protein complex assembly	GO:0043623	116	0.011
multicellular organismal signaling	GO:0035637	91	0.011
anatomical structure homeostasis	GO:0060249	145	0.011
cell type specific apoptotic process	GO:0097285	268	0.011
cellular response to interleukin 15	GO:0071350	2	0.010
response to reactive oxygen species	GO:0000302	56	0.010
leukocyte activation involved in immune response	GO:0002366	126	0.010
regulation of cytokine production	GO:0001817	266	0.010
regulation of ras protein signal transduction	GO:0046578	114	0.010
action potential	GO:0001508	78	0.010
cd4 positive alpha beta t cell activation	GO:0035710	45	0.010
regulation of leukocyte differentiation	GO:1902105	159	0.010
negative regulation of immune system process	GO:0002683	209	0.010
cellular chemical homeostasis	GO:0055082	215	0.010
forebrain development	GO:0030900	302	0.010
negative regulation of cell proliferation	GO:0008285	296	0.010
meiotic nuclear division	GO:0007126	115	0.010
regulation of mapk cascade	GO:0043408	248	0.010
rna processing	GO:0006396	105	0.010	Human Yeast
positive regulation of cellular respiration	GO:1901857	3	0.010
actin filament organization	GO:0007015	113	0.010

Ddx54 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.032
disease of anatomical entity	DOID:7	0.032
sensory system disease	DOID:0050155	0.013
retinal degeneration	DOID:8466	0.013
retinal disease	DOID:5679	0.013
eye disease	DOID:5614	0.013
eye and adnexa disease	DOID:1492	0.013
neuropathy	DOID:870	0.013
neuromuscular disease	DOID:440	0.013
central nervous system disease	DOID:331	0.012
neurodegenerative disease	DOID:1289	0.012
gastrointestinal system cancer	DOID:3119	0.010
organ system cancer	DOID:0050686	0.010
intestinal cancer	DOID:10155	0.010
cancer	DOID:162	0.010
disease of cellular proliferation	DOID:14566	0.010

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