Mus musculus

0 known processes

Eif4a1

eukaryotic translation initiation factor 4A1

(Aliases: BM-010,Ddx2a,Eif4)

Eif4a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
translational initiationGO:0006413240.601
Yeast
oocyte anterior posterior axis specificationGO:000731420.484
oxidation reduction processGO:00551143420.423
translationGO:0006412930.339
Yeast
oocyte constructionGO:000730820.285
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.228
regionalizationGO:00030023370.204
Fly
regulation of translationGO:0006417710.179
posttranscriptional regulation of gene expressionGO:00106081550.177
negative regulation of cellular component organizationGO:00511291940.174
apoptotic signaling pathwayGO:00971903060.174
regulation of mitotic cell cycleGO:00073461260.170
regulation of cytoskeleton organizationGO:00514931220.157
positive regulation of translationGO:0045727190.156
carbohydrate metabolic processGO:00059752300.155
stem cell differentiationGO:00488632680.151
Fly
nucleobase containing compound transportGO:0015931270.133
nucleoside phosphate catabolic processGO:19012922220.131
Yeast
nucleoside triphosphate metabolic processGO:00091412300.130
Yeast
negative regulation of purine nucleotide catabolic processGO:003312290.128
multicellular organismal agingGO:0010259240.126
Worm
oocyte axis specificationGO:000730920.123
spermatogenesisGO:00072832840.123
nucleic acid transportGO:0050657180.121
cellular response to dna damage stimulusGO:00069742070.120
Fly
positive regulation of cell deathGO:00109422240.119
cellular nitrogen compound catabolic processGO:00442702800.119
Yeast
microtubule cytoskeleton organizationGO:00002261570.114
Fly
regulation of translational initiationGO:0006446150.114
pole plasm assemblyGO:000731520.105
regulation of cell cycleGO:00517262810.097
aromatic compound catabolic processGO:00194392860.094
Yeast
development of primary sexual characteristicsGO:00451371430.092
positive regulation of dna templated transcription elongationGO:003278620.092
cytoplasmic transportGO:00164822340.092
positive regulation of programmed cell deathGO:00430682180.091
purine nucleoside metabolic processGO:00422782410.090
Yeast
regulation of nucleotide metabolic processGO:00061401690.089
generation of precursor metabolites and energyGO:00060911030.083
regulation of cellular component biogenesisGO:00440871810.080
establishment or maintenance of cytoskeleton polarityGO:003095220.079
rna localizationGO:0006403230.077
negative regulation of dna templated transcription terminationGO:006056710.075
regulation of rna splicingGO:0043484370.074
Fly
organophosphate catabolic processGO:00464342320.073
Yeast
regulation of organelle organizationGO:00330432890.073
regulation of nucleoside metabolic processGO:00091181300.071
response to oxidative stressGO:00069791230.071
regulation of anatomical structure sizeGO:00900661780.071
actin filament polymerizationGO:0030041440.070
organic cyclic compound catabolic processGO:19013612950.070
Yeast
positive regulation of apoptotic processGO:00430652170.068
small molecule biosynthetic processGO:00442831320.068
nucleobase containing small molecule metabolic processGO:00550863520.067
Yeast
positive regulation of cytoskeleton organizationGO:0051495490.067
regulation of mrna processingGO:0050684410.067
Fly
rna splicing via transesterification reactionsGO:0000375430.065
Fly
ossificationGO:00015032160.065
compound eye developmentGO:004874910.064
cellular response to cytokine stimulusGO:00713451890.064
regulation of actin filament lengthGO:0030832450.064
cellular homeostasisGO:00197252400.063
regulation of cell cycle processGO:00105641600.063
hexose metabolic processGO:0019318980.063
endocytosisGO:00068971680.061
regulation of protein complex assemblyGO:0043254830.060
regulation of cell projection organizationGO:00313442060.059
ribose phosphate metabolic processGO:00196932910.058
Yeast
ribonucleoside metabolic processGO:00091192450.058
Yeast
regulation of cell divisionGO:0051302760.057
regulation of actin filament polymerizationGO:0030833380.057
developmental maturationGO:00217001930.057
establishment or maintenance of cell polarityGO:0007163860.056
actin polymerization or depolymerizationGO:0008154540.056
maintenance of locationGO:0051235890.056
Worm
regulation of atp metabolic processGO:1903578170.055
cellularizationGO:000734910.055
Fly
cell adhesionGO:00071553290.054
purine nucleotide catabolic processGO:00061952110.053
Yeast
organonitrogen compound biosynthetic processGO:19015661920.053
nucleotide metabolic processGO:00091173320.053
Yeast
negative regulation of myeloid cell differentiationGO:0045638380.053
establishment of rna localizationGO:0051236180.052
nuclear transportGO:00511691390.052
meiotic cell cycleGO:00513211220.051
dna metabolic processGO:00062593030.051
negative regulation of atpase activityGO:003278020.050
organonitrogen compound catabolic processGO:19015652640.049
Yeast
monosaccharide metabolic processGO:00059961060.048
male gamete generationGO:00482322850.048
nucleoside triphosphate catabolic processGO:00091432050.048
Yeast
regulation of cellular response to stressGO:00801351590.048
myeloid cell differentiationGO:00300992330.047
regulation of mrna stabilityGO:0043488230.047
transmembrane transportGO:00550854120.045
female gamete generationGO:0007292740.045
Fly
nucleotide catabolic processGO:00091662170.044
Yeast
nucleoside monophosphate metabolic processGO:0009123850.044
Yeast
negative regulation of nucleotide catabolic processGO:003081290.044
regulation of apoptotic signaling pathwayGO:20012331970.043
chromatin organizationGO:00063252060.043
ribonucleotide metabolic processGO:00092592910.043
Yeast
adult locomotory behaviorGO:0008344910.043
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.042
Fly
purine nucleoside monophosphate catabolic processGO:0009128580.042
Yeast
cellular protein complex assemblyGO:00436231160.041
receptor mediated endocytosisGO:0006898510.041
fatty acid metabolic processGO:00066311210.041
ribonucleoside triphosphate metabolic processGO:00091992200.041
Yeast
regulation of mrna splicing via spliceosomeGO:0048024320.041
Fly
purine ribonucleotide metabolic processGO:00091502900.041
Yeast
mrna metabolic processGO:0016071840.040
Fly
poly a mrna export from nucleusGO:001697340.040
microtubule based processGO:00070172360.040
Fly
striated muscle tissue developmentGO:00147062930.040
cellular carbohydrate metabolic processGO:00442621190.040
regulation of carbohydrate metabolic processGO:0006109750.040
purine ribonucleoside monophosphate metabolic processGO:0009167800.040
Yeast
viral processGO:0016032410.039
dephosphorylationGO:00163111290.039
multi multicellular organism processGO:00447061090.039
cation homeostasisGO:00550802120.039
purine ribonucleoside metabolic processGO:00461282410.039
Yeast
negative regulation of protein complex disassemblyGO:0043242220.039
myosin filament assemblyGO:003103420.038
ras protein signal transductionGO:0007265770.038
positive regulation of cell cycle processGO:0090068610.038
stem cell developmentGO:00488642190.037
Fly
regulation of dna templated transcription terminationGO:003155410.037
synaptic transmissionGO:00072683290.036
purine nucleotide metabolic processGO:00061633020.036
Yeast
cell maturationGO:00484691270.035
polysaccharide metabolic processGO:0005976390.035
intracellular protein transportGO:00068862040.035
mrna export from nucleusGO:0006406110.034
macromolecular complex disassemblyGO:0032984430.033
dna repairGO:00062811070.033
establishment of protein localization to organelleGO:00725941180.033
body morphogenesisGO:0010171450.033
chromatin modificationGO:00165681870.033
organic anion transportGO:00157111370.033
striated muscle myosin thick filament assemblyGO:007168810.033
placenta developmentGO:00018901400.033
positive regulation of growthGO:00459271040.032
positive regulation of cell developmentGO:00107202370.032
ribonucleoside triphosphate catabolic processGO:00092031990.032
Yeast
regulation of actin polymerization or depolymerizationGO:0008064450.032
symbiosis encompassing mutualism through parasitismGO:0044403830.031
nitrogen compound transportGO:00717052710.031
morphogenesis of embryonic epitheliumGO:00163311590.031
carbohydrate catabolic processGO:0016052320.031
positive regulation of mrna processingGO:0050685160.031
energy derivation by oxidation of organic compoundsGO:0015980770.031
establishment of organelle localizationGO:00516561220.031
cellular amino acid metabolic processGO:00065201030.031
g1 s transition of mitotic cell cycleGO:0000082570.030
regulation of protein complex disassemblyGO:0043244280.030
positive regulation of organelle organizationGO:00106381280.030
heterocycle catabolic processGO:00467002800.030
Yeast
positive regulation of cell cycleGO:0045787920.030
muscle cell differentiationGO:00426922610.030
sensory perceptionGO:00076002450.030
purine containing compound metabolic processGO:00725213110.030
Yeast
cellular response to lipidGO:00713961450.030
positive regulation of nervous system developmentGO:00519622210.030
mitotic cell cycleGO:00002781950.029
Fly
organic hydroxy compound metabolic processGO:19016152030.029
response to organic cyclic compoundGO:00140701980.029
negative regulation of nucleotide metabolic processGO:0045980160.029
lymphocyte proliferationGO:00466511640.029
mitotic cell cycle processGO:19030471590.029
Fly
mrna transportGO:0051028130.029
negative regulation of cellular protein metabolic processGO:00322692470.029
monocarboxylic acid metabolic processGO:00327871910.029
intracellular mrna localizationGO:000829840.028
cell divisionGO:00513011200.028
Fly
protein import into nucleusGO:0006606950.027
cellular response to organic cyclic compoundGO:0071407870.027
glucose metabolic processGO:0006006920.027
segmentationGO:0035282930.027
carbohydrate derivative biosynthetic processGO:19011371830.027
negative regulation of nucleoside metabolic processGO:0045978110.026
regulation of actin cytoskeleton organizationGO:0032956840.026
striated muscle contractionGO:0006941450.026
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.025
organism emergence from protective structureGO:007168440.025
maternal determination of anterior posterior axis embryoGO:000835820.025
regulation of purine nucleotide catabolic processGO:00331211220.025
regulation of homeostatic processGO:00328441820.025
regulation of endocytosisGO:0030100690.025
cofactor transportGO:005118140.025
dna recombinationGO:0006310920.025
leukocyte proliferationGO:00706611720.025
nucleocytoplasmic transportGO:00069131390.025
very long chain fatty acid metabolic processGO:000003880.024
response to acid chemicalGO:00011011110.024
multicellular organism growthGO:00352641610.024
atp metabolic processGO:0046034750.024
Yeast
lung developmentGO:00303241640.024
locomotory behaviorGO:00076261950.024
protein polymerizationGO:0051258570.023
skeletal system developmentGO:00015013560.023
synaptic vesicle transportGO:0048489570.023
small gtpase mediated signal transductionGO:0007264970.023
organelle localizationGO:00516401790.023
meiotic cell cycle processGO:1903046770.023
cell type specific apoptotic processGO:00972852680.022
response to organonitrogen compoundGO:00102432460.022
glycogen metabolic processGO:0005977320.022
dendritic spine organizationGO:0097061260.022
neural tube formationGO:00018411080.022
positive regulation of homeostatic processGO:0032846640.022
molting cycleGO:0042303900.021
chromosome segregationGO:0007059480.021
nuclear divisionGO:00002801580.021
Fly
ribonucleoside catabolic processGO:00424542060.021
Yeast
muscle system processGO:00030121410.021
nucleoside phosphate metabolic processGO:00067533380.021
Yeast
nucleoside catabolic processGO:00091642060.021
Yeast
heart contractionGO:0060047930.021
regulation of nuclear divisionGO:0051783560.021
muscle tissue developmentGO:00605373080.021
blood vessel morphogenesisGO:00485142850.021
regulation of cell motilityGO:20001452360.021
purine ribonucleoside monophosphate catabolic processGO:0009169570.020
Yeast
digestive tract developmentGO:00485651900.020
positive regulation of mrna metabolic processGO:1903313170.020
positive regulation of cellular catabolic processGO:00313311480.020
purine nucleoside monophosphate metabolic processGO:0009126810.020
Yeast
cellular chemical homeostasisGO:00550822150.020
circulatory system processGO:00030131970.020
dna dependent dna replication maintenance of fidelityGO:004500530.020
regulation of cellular catabolic processGO:00313292420.020
carbohydrate biosynthetic processGO:0016051740.020
epidermis developmentGO:00085441870.020
protein targetingGO:00066051430.019
determination of adult lifespanGO:0008340110.019
Worm
negative regulation of immune system processGO:00026832090.019
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
Yeast
positive regulation of actin filament polymerizationGO:0030838260.019
male sex differentiationGO:00466611090.019
purine ribonucleoside triphosphate catabolic processGO:00092071990.019
Yeast
genitalia developmentGO:0048806370.019
response to inorganic substanceGO:0010035960.019
protein methylationGO:0006479810.019
protein localization to nucleusGO:00345041210.019
positive regulation of apoptotic signaling pathwayGO:2001235950.019
regulation of cell cycle phase transitionGO:1901987770.019
extracellular matrix organizationGO:00301981470.019
ribonucleoside monophosphate metabolic processGO:0009161800.019
Yeast
actin filament depolymerizationGO:0030042150.019
cellular component assembly involved in morphogenesisGO:00109271390.019
regulation of microtubule based processGO:0032886520.018
carboxylic acid biosynthetic processGO:0046394860.018
purine ribonucleoside catabolic processGO:00461302050.018
Yeast
myosin filament organizationGO:003103330.018
b cell activationGO:00421131610.018
glycosyl compound metabolic processGO:19016572460.018
Yeast
protein complex disassemblyGO:0043241400.018
positive regulation of mitotic cell cycleGO:0045931410.018
hatchingGO:003518840.018
mesenchymal cell developmentGO:0014031930.018
rna transportGO:0050658180.018
cellular lipid metabolic processGO:00442553230.018
positive regulation of protein modification processGO:00314012990.018
nucleoside monophosphate catabolic processGO:0009125590.018
Yeast
maternal process involved in female pregnancyGO:0060135320.018
mrna processingGO:0006397630.018
Fly
skeletal myofibril assemblyGO:001486640.017
actin filament organizationGO:00070151130.017
regulation of lymphocyte activationGO:00512492400.017
negative regulation of rna splicingGO:0033119120.017
monocarboxylic acid biosynthetic processGO:0072330610.017
mitochondrion distributionGO:004831140.017
mesenchyme developmentGO:00604851520.017
regulation of cell adhesionGO:00301551540.017
multicellular organismal reproductive behaviorGO:0033057230.017
mitotic centrosome separationGO:000710040.017
oocyte differentiationGO:0009994350.017
glucose homeostasisGO:00425931280.017
muscle cell developmentGO:00550011330.017
negative regulation of apoptotic signaling pathwayGO:20012341040.017
cellular response to oxidative stressGO:0034599760.017
spermatid differentiationGO:00485151150.017
regulation of cell substrate adhesionGO:0010810730.017
neural tube closureGO:0001843900.017
purine nucleoside triphosphate metabolic processGO:00091442260.016
Yeast
regulation of cellular component sizeGO:00325351210.016
atp catabolic processGO:0006200550.016
Yeast
response to nutrient levelsGO:00316671090.016
establishment of vesicle localizationGO:0051650810.016
regulation of protein localizationGO:00328802310.016
regulation of cellular ketone metabolic processGO:0010565660.016
ribonucleotide catabolic processGO:00092612080.016
Yeast
gonad developmentGO:00084061410.016
blood circulationGO:00080151950.016
cation transportGO:00068123990.016
peptidyl amino acid modificationGO:00181933360.016
glycosyl compound catabolic processGO:19016582060.016
Yeast
synaptic vesicle localizationGO:0097479590.016
methylationGO:00322591340.016
organic acid transportGO:00158491010.015
meiotic nuclear divisionGO:00071261150.015
centrosome separationGO:005129940.015
lipid storageGO:0019915360.015
Worm
regulation of ras protein signal transductionGO:00465781140.015
innate immune responseGO:00450871570.015
serine family amino acid metabolic processGO:000906970.015
germ cell developmentGO:00072811850.015
Fly
positive regulation of proteolysisGO:0045862850.015
extracellular structure organizationGO:00430621480.015
maternal placenta developmentGO:0001893200.015
regulation of actin filament depolymerizationGO:0030834130.015
regulation of cell projection assemblyGO:0060491380.015
purine nucleoside catabolic processGO:00061522050.015
Yeast
negative regulation of actin filament depolymerizationGO:003083590.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
respiratory system developmentGO:00605411900.015
regulation of response to dna damage stimulusGO:2001020340.014
rna processingGO:00063961050.014
Fly
cellular amine metabolic processGO:0044106440.014
nucleotide biosynthetic processGO:0009165780.014
epithelial tube morphogenesisGO:00605623030.014
cellular ketone metabolic processGO:0042180840.014
forebrain developmentGO:00309003020.014
cellular metal ion homeostasisGO:00068751510.014
establishment or maintenance of bipolar cell polarityGO:0061245210.014
axonogenesisGO:00074092740.014
ribonucleoside monophosphate catabolic processGO:0009158570.014
Yeast
divalent inorganic cation homeostasisGO:00725071380.014
ribonucleoprotein complex disassemblyGO:003298830.014
cellular ion homeostasisGO:00068731650.014
regulation of vesicle mediated transportGO:00606271390.014
regulation of synaptic growth at neuromuscular junctionGO:000858240.014
negative regulation of organelle organizationGO:0010639900.014
cell cycle g1 s phase transitionGO:0044843570.014
actin cytoskeleton organizationGO:00300362200.014
positive regulation of atp biosynthetic processGO:200117120.014
reactive oxygen species metabolic processGO:0072593840.014
negative regulation of translationGO:0017148220.014
cellular glucan metabolic processGO:0006073320.014
lateral inhibitionGO:004633110.013
mrna splicing via spliceosomeGO:0000398430.013
Fly
male anatomical structure morphogenesisGO:009059840.013
mitochondrial transportGO:0006839360.013
regulation of cell activationGO:00508652890.013
regulation of lamellipodium assemblyGO:001059130.013
oocyte developmentGO:0048599330.013
calcium ion homeostasisGO:00550741270.013
histone modificationGO:00165701590.013
heart morphogenesisGO:00030071780.013
nucleoside metabolic processGO:00091162460.013
Yeast
nuclear exportGO:0051168340.013
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.013
regulation of purine nucleotide metabolic processGO:19005421690.013
cellular response to carbohydrate stimulusGO:0071322500.013
establishment of synaptic vesicle localizationGO:0097480570.013
skin developmentGO:00435882200.013
mitochondrion organizationGO:00070051340.013
organelle fissionGO:00482851700.013
Fly
negative regulation of protein metabolic processGO:00512482820.013
regulation of establishment of protein localizationGO:00702011810.012
membrane organizationGO:00610242450.012
adult behaviorGO:00305341350.012
macromolecule catabolic processGO:00090572810.012
skeletal system morphogenesisGO:00487052030.012
nucleoside phosphate biosynthetic processGO:1901293790.012
regulation of body fluid levelsGO:00508781620.012
macromolecule methylationGO:00434141200.012
mapk cascadeGO:00001652810.012
glycoprotein metabolic processGO:00091001160.012
positive regulation of cell divisionGO:0051781310.012
regulation of proteolysisGO:00301621640.012
neural tube developmentGO:00219151600.012
positive regulation of neuron differentiationGO:00456661410.012
single organism cell adhesionGO:00986021560.012
rna splicingGO:0008380540.012
Fly
muscle contractionGO:00069361010.012
nucleoside biosynthetic processGO:0009163210.012
regulation of meiotic cell cycleGO:0051445340.012
regulation of exit from mitosisGO:000709610.012
barbed end actin filament cappingGO:005101660.012
cell substrate adhesionGO:00315891300.012
regulation of cellular carbohydrate metabolic processGO:0010675750.012
posttranscriptional gene silencing by rnaGO:0035194100.011
cellular response to hexose stimulusGO:0071331470.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
Yeast
positive regulation of cellular amine metabolic processGO:003324050.011
regulation of mitosisGO:0007088290.011
cellular senescenceGO:0090398110.011
regulation of neuron projection developmentGO:00109751690.011
ribonucleoside biosynthetic processGO:0042455210.011
inflammatory responseGO:00069542440.011
regulation of transferase activityGO:00513382630.011
striated muscle cell developmentGO:00550021250.011
embryonic organ morphogenesisGO:00485622760.011
determination of left right symmetryGO:0007368800.011
cellular protein catabolic processGO:00442571550.011
negative regulation of phosphate metabolic processGO:00459361840.011
embryonic skeletal system developmentGO:00487061200.011
regulation of mrna metabolic processGO:1903311430.011
Fly
positive regulation of attachment of spindle microtubules to kinetochoreGO:005198720.011
selenium compound metabolic processGO:000188730.011
negative regulation of phosphorus metabolic processGO:00105631840.011
regulation of neuron differentiationGO:00456642810.011
glycoprotein biosynthetic processGO:0009101890.011
regulation of rna stabilityGO:0043487260.011
skeletal muscle organ developmentGO:00605381630.010
positive regulation of cellular carbohydrate metabolic processGO:0010676290.010
embryonic heart tube developmentGO:0035050650.010
negative regulation of phagocytosisGO:005076540.010
cardiac muscle contractionGO:0060048320.010
anatomical structure homeostasisGO:00602491450.010
sensory organ morphogenesisGO:00905962420.010
regulation of generation of precursor metabolites and energyGO:0043467380.010
myeloid cell homeostasisGO:00022621140.010
binding of sperm to zona pellucidaGO:0007339340.010
regulation of membrane potentialGO:00423911920.010
positive regulation of cell substrate adhesionGO:0010811470.010
ribose phosphate biosynthetic processGO:0046390590.010
carboxylic acid transportGO:00469421000.010
lipid biosynthetic processGO:00086101790.010
carbohydrate derivative catabolic processGO:19011362310.010
Yeast
response to steroid hormoneGO:0048545560.010
cell agingGO:0007569350.010
ion transmembrane transportGO:00342203610.010

Eif4a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.237
central nervous system diseaseDOID:33100.237
nervous system diseaseDOID:86300.237
neurodegenerative diseaseDOID:128900.192
amyotrophic lateral sclerosisDOID:33200.055
motor neuron diseaseDOID:23100.055
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.011