Mus musculus

207 known processes

Esr1

estrogen receptor 1 (alpha)

(Aliases: AU041214,Nr3a1,AA420328,Estra,ERalpha,ERa,Estr,ER[a],ER-alpha,ESR)

Esr1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuropeptide signaling pathwayGO:0007218191.000
positive regulation of inositol phosphate biosynthetic processGO:006073221.000
wnt signaling pathway involved in kidney developmentGO:006128921.000
cellular response to gonadotropin stimulusGO:007137140.999
creatinine metabolic processGO:004644930.999
development of secondary male sexual characteristicsGO:004654430.999
rhythmic processGO:00485111740.999
female sex differentiationGO:0046660840.998
positive regulation of intracellular estrogen receptor signaling pathwayGO:003314840.998
regulation of steroid hormone biosynthetic processGO:009003040.998
regulation of fatty acid oxidationGO:0046320100.998
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189300.997
cellular amino acid metabolic processGO:00065201030.997
positive regulation of intracellular steroid hormone receptor signaling pathwayGO:003314540.997
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.997
response to extracellular stimulusGO:00099911270.997
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.996
steroid metabolic processGO:00082021190.996
gland developmentGO:00487323300.995
hormone mediated signaling pathwayGO:0009755230.995
Human Zebrafish Mouse Rat
morphogenesis of a branching structureGO:00017632030.995
tertiary branching involved in mammary gland duct morphogenesisGO:006074830.995
development of primary female sexual characteristicsGO:0046545730.994
negative regulation of cell proliferationGO:00082852960.994
Mouse Rat
spermatogenesis exchange of chromosomal proteinsGO:003509340.993
regulation of steroid biosynthetic processGO:0050810260.992
sertoli cell proliferationGO:006001150.991
Rat
glucose homeostasisGO:00425931280.991
carbohydrate metabolic processGO:00059752300.990
regulation of feeding behaviorGO:006025930.990
follicle stimulating hormone secretionGO:004688410.990
luteinizationGO:000155380.990
creatine metabolic processGO:000660040.990
taurine metabolic processGO:001953040.989
steroid hormone mediated signaling pathwayGO:004340160.988
Human Zebrafish Rat
response to peptide hormoneGO:00434341270.988
female gonad developmentGO:0008585710.987
regulation of carbohydrate biosynthetic processGO:0043255400.986
canonical wnt signaling pathway involved in metanephric kidney developmentGO:006129020.986
succinate metabolic processGO:000610540.985
spermatid developmentGO:00072861080.985
cellular water homeostasisGO:000999220.984
response to alcoholGO:0097305480.983
Human Zebrafish Rat
regulation of nitrogen cycle metabolic processGO:190331410.982
cellular response to hormone stimulusGO:00328701500.981
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143180.981
Mouse
cyclic nucleotide biosynthetic processGO:0009190440.981
morphogenesis of a branching epitheliumGO:00611381930.981
alpha amino acid metabolic processGO:1901605590.980
acetate ester metabolic processGO:190061930.980
organ growthGO:00352651170.980
development of primary sexual characteristicsGO:00451371430.979
positive regulation of cyclic nucleotide biosynthetic processGO:0030804240.979
spermatid differentiationGO:00485151150.978
maternal process involved in female pregnancyGO:0060135320.977
regulation of glucose metabolic processGO:0010906600.976
pattern recognition receptor signaling pathwayGO:0002221470.975
monocarboxylic acid metabolic processGO:00327871910.975
acylglycerol homeostasisGO:0055090160.972
muscle tissue developmentGO:00605373080.972
follicle stimulating hormone signaling pathwayGO:004269930.972
development of secondary sexual characteristicsGO:0045136110.971
response to organic cyclic compoundGO:00140701980.970
sertoli cell differentiationGO:0060008180.970
Rat
epithelial tube morphogenesisGO:00605623030.969
mammary gland epithelium developmentGO:0061180650.969
regulation of fatty acid metabolic processGO:0019217280.969
gonad developmentGO:00084061410.967
chromatin modificationGO:00165681870.967
cyclic purine nucleotide metabolic processGO:0052652430.966
regulation of toll like receptor signaling pathwayGO:0034121200.964
placenta developmentGO:00018901400.962
Mouse Rat
negative regulation of epithelial cell proliferationGO:0050680640.962
Mouse
valine metabolic processGO:000657340.960
glucose metabolic processGO:0006006920.959
regulation of blood pressureGO:0008217930.958
multicellular organism growthGO:00352641610.958
spermatogenesisGO:00072832840.957
fatty acid metabolic processGO:00066311210.957
negative regulation of bone resorptionGO:004577960.954
regulation of fatty acid beta oxidationGO:003199810.954
cellular amine metabolic processGO:0044106440.953
development of primary male sexual characteristicsGO:0046546880.953
lipid transportGO:0006869980.952
prostate gland growthGO:0060736130.952
positive regulation of growthGO:00459271040.952
regulation of camp metabolic processGO:0030814300.952
prolactin signaling pathwayGO:003816150.951
ovulation cycleGO:0042698590.951
ovarian follicle developmentGO:0001541400.951
male gamete generationGO:00482322850.949
regulation of hormone levelsGO:00108172110.948
carbohydrate biosynthetic processGO:0016051740.948
platelet derived growth factor receptor signaling pathwayGO:0048008320.948
isoleucine metabolic processGO:000654940.947
positive regulation of nucleotide biosynthetic processGO:0030810260.945
response to organonitrogen compoundGO:00102432460.944
mammary gland branching involved in pregnancyGO:006074560.942
regulation of cellular ketone metabolic processGO:0010565660.940
female genitalia developmentGO:0030540140.940
intracellular receptor signaling pathwayGO:0030522740.940
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.939
circadian rhythmGO:00076231140.939
mapk cascadeGO:00001652810.937
Rat
positive regulation of cholesterol homeostasisGO:200018920.936
regulation of myeloid leukocyte differentiationGO:0002761580.933
regulation of leukocyte differentiationGO:19021051590.931
cell cell signaling involved in kidney developmentGO:006099520.930
mammary gland lobule developmentGO:0061377220.930
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.930
b cell activationGO:00421131610.930
regulation of cellular carbohydrate metabolic processGO:0010675750.929
seminiferous tubule developmentGO:0072520140.929
positive regulation of carbohydrate metabolic processGO:0045913300.928
positive regulation of mammary gland involutionGO:190352140.928
g protein coupled receptor signaling pathwayGO:00071862430.928
Rat
inositol phosphate biosynthetic processGO:003295860.926
peptidyl amino acid modificationGO:00181933360.926
cartilage development involved in endochondral bone morphogenesisGO:0060351240.926
sertoli cell developmentGO:0060009150.925
Rat
extrinsic apoptotic signaling pathwayGO:00971911260.923
tyrosine phosphorylation of stat proteinGO:0007260230.921
negative regulation of bone remodelingGO:004685160.919
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.919
tyrosine phosphorylation of stat5 proteinGO:004250690.918
male sex differentiationGO:00466611090.917
cell growthGO:00160491300.916
response to peptideGO:19016521360.915
regulation of secretion by cellGO:19035302490.913
response to steroid hormoneGO:0048545560.912
regulation of cellular amine metabolic processGO:0033238200.911
cellular lipid metabolic processGO:00442553230.910
Rat
regulation of natural killer cell differentiationGO:0032823110.910
regulation of acetylcholine metabolic processGO:006040810.909
response to corticosteroidGO:0031960200.909
response to nutrient levelsGO:00316671090.909
camp metabolic processGO:0046058400.908
epithelial cell differentiation involved in prostate gland developmentGO:0060742130.905
Mouse
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193200.905
hormone metabolic processGO:0042445860.904
metanephric glomerulus developmentGO:0072224130.904
primary ovarian follicle growthGO:000154520.903
negative regulation of cell growthGO:0030308440.903
myeloid leukocyte activationGO:0002274830.901
regulation of protein serine threonine kinase activityGO:00719001570.899
regulation of lipid biosynthetic processGO:0046890540.897
allantoin metabolic processGO:000025530.896
positive regulation of camp metabolic processGO:0030816190.895
adrenal gland developmentGO:0030325180.889
positive regulation of transferase activityGO:00513471670.887
positive regulation of fatty acid oxidationGO:004632140.886
positive regulation of apoptotic process involved in morphogenesisGO:190233940.884
citrate metabolic processGO:000610130.882
tissue remodelingGO:00487711020.882
cellular response to nutrient levelsGO:0031669640.882
canonical wnt signaling pathwayGO:00600701300.881
regulation of inositol trisphosphate biosynthetic processGO:003296030.877
activation of adenylate cyclase activityGO:000719040.877
regulation of transferase activityGO:00513382630.876
alcohol biosynthetic processGO:0046165430.874
regulation of inositol phosphate biosynthetic processGO:001091930.872
regulation of kinase activityGO:00435492490.870
lipid biosynthetic processGO:00086101790.869
negative regulation of peptide hormone secretionGO:0090278160.868
regulation of carbohydrate metabolic processGO:0006109750.865
regulation of organ morphogenesisGO:20000271440.863
regulation of protein kinase activityGO:00458592320.863
regulation of hormone secretionGO:0046883880.862
regulation of nucleotide biosynthetic processGO:0030808340.862
toll like receptor signaling pathwayGO:0002224380.861
ammonia assimilation cycleGO:001967620.861
metanephric nephron developmentGO:0072210340.860
amine metabolic processGO:0009308450.859
lymphocyte differentiationGO:00300982420.857
positive regulation of apoptotic signaling pathwayGO:2001235950.857
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.856
peptide secretionGO:00027901140.855
positive regulation of cellular amino acid metabolic processGO:004576430.855
cyclic nucleotide metabolic processGO:0009187590.854
amide transportGO:00428861380.852
branching involved in mammary gland duct morphogenesisGO:0060444270.851
regulation of camp biosynthetic processGO:0030817250.848
positive regulation of inositol trisphosphate biosynthetic processGO:003296220.847
regulation of platelet derived growth factor receptor signaling pathwayGO:001064090.846
renal tubule developmentGO:0061326870.846
growth hormone receptor signaling pathwayGO:006039670.845
regulation of morphogenesis of a branching structureGO:0060688530.844
cardiac muscle tissue developmentGO:00487381300.839
female gamete generationGO:0007292740.838
negative regulation of secretionGO:0051048610.837
regulation of jak stat cascadeGO:0046425340.835
ureteric bud developmentGO:0001657940.835
peptide transportGO:00158331330.835
apoptotic process involved in mammary gland involutionGO:006005740.835
cellular response to organic cyclic compoundGO:0071407870.833
cellular ketone metabolic processGO:0042180840.833
platelet derived growth factor receptor alpha signaling pathwayGO:003579030.829
negative regulation of toll like receptor signaling pathwayGO:0034122140.828
dicarboxylic acid metabolic processGO:0043648180.827
epithelial cell proliferationGO:00506731740.826
progesterone metabolic processGO:004244840.822
immune response activating signal transductionGO:00027571160.819
androgen metabolic processGO:0008209110.819
hepatocyte growth factor receptor signaling pathwayGO:004801230.818
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.817
positive regulation of protein kinase activityGO:00458601440.817
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.816
peptidyl tyrosine phosphorylationGO:00181081430.816
cellular ion homeostasisGO:00068731650.815
Rat
nephron tubule developmentGO:0072080840.813
regulation of vitamin d biosynthetic processGO:006055610.811
vitamin d biosynthetic processGO:004236830.811
negative regulation of hormone secretionGO:0046888200.810
inositol trisphosphate metabolic processGO:003295750.808
negative regulation of insulin secretionGO:0046676140.808
positive regulation of protein phosphorylationGO:00019342420.805
negative regulation of secretion by cellGO:1903531540.804
positive regulation of mapk cascadeGO:00434101700.803
Rat
metanephric tubule developmentGO:0072170180.802
regulation of triglyceride metabolic processGO:0090207170.799
Rat
kidney epithelium developmentGO:00720731210.790
maternal placenta developmentGO:0001893200.790
Rat
regulation of innate immune responseGO:0045088910.790
vagina developmentGO:0060068110.789
monosaccharide metabolic processGO:00059961060.785
cell fate commitmentGO:00451652100.784
cellular response to extracellular stimulusGO:0031668810.783
drug catabolic processGO:004273720.781
organic acid transportGO:00158491010.776
carbon catabolite activation of transcriptionGO:004599140.776
inositol trisphosphate biosynthetic processGO:003295950.775
regulation of urea metabolic processGO:003425510.775
cell adhesionGO:00071553290.774
asymmetric neuroblast divisionGO:005505910.774
regulation of cellular amino acid metabolic processGO:000652150.773
muscle system processGO:00030121410.772
multi multicellular organism processGO:00447061090.772
cellular lactam metabolic processGO:007233830.772
positive regulation of protein acetylationGO:190198590.771
cell cell signaling involved in metanephros developmentGO:007220420.769
innate immune response activating signal transductionGO:0002758500.769
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.767
Rat
intracellular steroid hormone receptor signaling pathwayGO:0030518290.767
Human Zebrafish Mouse Rat
metanephric glomerular mesangium developmentGO:007222330.761
skin developmentGO:00435882200.761
cellular carbohydrate metabolic processGO:00442621190.760
glucocorticoid mediated signaling pathwayGO:004340230.758
response to insulinGO:00328681000.756
kidney developmentGO:00018222130.752
regulation of cell cycleGO:00517262810.750
ovulation from ovarian follicleGO:000154290.747
carboxylic acid transportGO:00469421000.746
regulation of peptide secretionGO:0002791770.744
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356880.738
activation of transmembrane receptor protein tyrosine kinase activityGO:000717130.737
cellular response to follicle stimulating hormone stimulusGO:007137210.736
positive regulation of insulin receptor signaling pathwayGO:004662840.733
metanephric nephron morphogenesisGO:0072273190.732
myeloid cell differentiationGO:00300992330.726
nephron developmentGO:00720061090.724
multicellular organismal homeostasisGO:00488711640.723
embryonic placenta developmentGO:0001892980.722
Mouse
small molecule biosynthetic processGO:00442831320.720
response to bile acidGO:190341210.719
negative regulation of cytokine productionGO:0001818840.718
activation of innate immune responseGO:0002218560.715
positive regulation of protein modification processGO:00314012990.714
erythrocyte differentiationGO:0030218880.711
response to cholesterolGO:007072340.710
cellular response to biotic stimulusGO:0071216920.709
regulation of defense responseGO:00313472330.707
regulation of adrenergic receptor signaling pathwayGO:007187740.706
regulation of lipid metabolic processGO:00192161180.705
Rat
regulation of tissue remodelingGO:0034103380.701
skeletal system morphogenesisGO:00487052030.698
regulation of blood vessel sizeGO:0050880560.697
regulation of mapk cascadeGO:00434082480.692
Rat
cellular response to peptideGO:1901653920.692
cellular senescenceGO:0090398110.688
regulation of lipid kinase activityGO:0043550140.687
response to testosteroneGO:003357430.686
peptidyl tyrosine modificationGO:00182121450.684
hormone secretionGO:00468791280.683
jak stat cascadeGO:0007259420.681
water homeostasisGO:0030104270.679
inner ear receptor cell differentiationGO:0060113610.678
regulation of myeloid cell differentiationGO:0045637960.676
cellular response to cytokine stimulusGO:00713451890.676
lateral mesoderm morphogenesisGO:004836930.674
cyclic nucleotide mediated signalingGO:0019935180.672
inner ear receptor stereocilium organizationGO:0060122230.671
prostate glandular acinus developmentGO:0060525120.668
cytokine productionGO:00018163190.667
regulation of cell morphogenesis involved in differentiationGO:00107691510.666
leydig cell differentiationGO:0033327100.665
cellular response to growth factor stimulusGO:00713631970.665
cellular response to organonitrogen compoundGO:00714171450.664
positive regulation of b cell proliferationGO:0030890240.664
muscle cell migrationGO:0014812190.663
nucleoside phosphate biosynthetic processGO:1901293790.663
regulation of cyclic nucleotide metabolic processGO:0030799400.660
regulation of kidney developmentGO:0090183400.653
regulation of camp mediated signalingGO:004394970.652
cell differentiation involved in kidney developmentGO:0061005330.649
positive regulation of neuron differentiationGO:00456661410.647
response to lipopolysaccharideGO:00324961280.645
somatostatin receptor signaling pathwayGO:003816920.643
positive regulation of leukocyte differentiationGO:1902107860.642
metanephros morphogenesisGO:0003338240.641
positive regulation of defense responseGO:00313491240.639
positive regulation of innate immune responseGO:0045089800.637
prostate gland morphogenesisGO:0060512320.636
regulation of tube sizeGO:0035150570.635
dna metabolic processGO:00062593030.633
wnt signaling pathwayGO:00160551880.631
positive regulation of activated t cell proliferationGO:004210480.629
lateral sprouting involved in mammary gland duct morphogenesisGO:006059920.628
carbon catabolite regulation of transcriptionGO:004599040.628
trophectodermal cellular morphogenesisGO:000183130.623
Mouse
metanephric nephron tubule developmentGO:0072234160.623
camp biosynthetic processGO:0006171310.622
epidermis developmentGO:00085441870.617
regulation of cytokine productionGO:00018172660.615
long term synaptic potentiationGO:0060291250.615
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.613
regulation of organelle organizationGO:00330432890.612
ribose phosphate biosynthetic processGO:0046390590.608
cell differentiation involved in metanephros developmentGO:0072202120.608
ureteric bud morphogenesisGO:0060675620.606
regulation of lyase activityGO:0051339130.606
negative regulation of peptide secretionGO:0002792160.604
trophectodermal cell proliferationGO:000183420.604
Mouse
positive regulation of translational initiation by ironGO:004599420.600
leukocyte proliferationGO:00706611720.594
triglyceride homeostasisGO:0070328150.592
regulation of canonical wnt signaling pathwayGO:0060828820.592
insulin secretionGO:0030073890.592
regulation of peptide transportGO:0090087910.590
somatostatin signaling pathwayGO:003817020.587
prostate gland developmentGO:0030850480.582
regulation of synaptic growth at neuromuscular junctionGO:000858240.580
negative regulation of cell motilityGO:2000146610.580
t cell activationGO:00421102890.580
embryonic organ morphogenesisGO:00485622760.577
regulation of glutamate metabolic processGO:200021110.576
connective tissue developmentGO:00614481790.574
positive regulation of map kinase activityGO:0043406840.570
oxidation reduction processGO:00551143420.569
Human
positive regulation of smooth muscle cell migrationGO:001491140.568
carbohydrate derivative biosynthetic processGO:19011371830.566
cellular response to growth hormone stimulusGO:007137870.565
b cell differentiationGO:0030183780.565
regulation of lymphocyte proliferationGO:00506701170.564
regulation of cell growthGO:0001558910.563
organic anion transportGO:00157111370.563
positive regulation of adenylate cyclase activityGO:004576280.563
positive regulation of male gonad developmentGO:200002060.563
nucleotide biosynthetic processGO:0009165780.561
regulation of lymphocyte activationGO:00512492400.561
innate immune responseGO:00450871570.560
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.559
regulation of circadian sleep wake cycleGO:004274930.557
mesonephric tubule developmentGO:0072164940.556
polysaccharide metabolic processGO:0005976390.553
cytoplasmic transportGO:00164822340.552
regulation of gluconeogenesisGO:0006111300.551
protein kinase b signalingGO:0043491740.551
embryonic skeletal system developmentGO:00487061200.548
maintenance of locationGO:0051235890.548
developmental maturationGO:00217001930.547
Mouse
activation of mapk activityGO:0000187590.547
positive regulation of cellular amine metabolic processGO:003324050.544
positive regulation of transcription by galactoseGO:000041110.543
retina development in camera type eyeGO:00600411190.542
nephron morphogenesisGO:0072028690.539
regulation of t cell differentiationGO:0045580830.539
immune response regulating signaling pathwayGO:00027641250.536
response to estrogenGO:0043627240.535
regulation of intracellular estrogen receptor signaling pathwayGO:003314680.534
regulation of secretionGO:00510462740.534
regulation of catecholamine uptake involved in synaptic transmissionGO:005194020.533
b cell proliferationGO:0042100530.531
positive regulation of histone h3 k9 methylationGO:005157440.530
hormone biosynthetic processGO:0042446160.529
regulation of integrin biosynthetic processGO:004511310.528
cytokine mediated signaling pathwayGO:00192211150.527
myeloid leukocyte differentiationGO:00025731190.526
sperm chromatin condensationGO:003509280.526
cell proliferation in hindbrainGO:0021534100.525
anatomical structure homeostasisGO:00602491450.525
camp mediated signalingGO:0019933150.525
regulation of tolerance induction to self antigenGO:000264910.524
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.524
Human
regulation of hormone metabolic processGO:0032350150.524
regulation of osteoclast differentiationGO:0045670360.523
negative regulation of lipid metabolic processGO:0045833300.522
Rat
regulation of leukocyte proliferationGO:00706631210.517
regulation of monooxygenase activityGO:003276870.515
Human
positive regulation of cyclic nucleotide metabolic processGO:0030801240.508
alpha amino acid catabolic processGO:1901606180.507
fat soluble vitamin biosynthetic processGO:004236240.504
regulation of cyclase activityGO:0031279130.504
histone acetylationGO:0016573410.503
negative regulation of homeostatic processGO:0032845710.503
lipid storageGO:0019915360.501
purine nucleotide biosynthetic processGO:0006164650.498
plasma membrane long chain fatty acid transportGO:001591110.497
mesonephric tubule morphogenesisGO:0072171630.493
positive regulation of kinase activityGO:00336741550.493
renal system developmentGO:00720012250.492
biological phaseGO:0044848200.491
metanephric nephron epithelium developmentGO:0072243190.491
positive regulation of lymphocyte differentiationGO:0045621610.491
chromatin organizationGO:00063252060.489
g protein coupled receptor signaling pathway involved in heart processGO:008610340.488
cellular chemical homeostasisGO:00550822150.485
Rat
negative regulation of protein secretionGO:0050709200.484
spermatid nucleus differentiationGO:0007289190.482
negative regulation of cell developmentGO:00107211690.480
regulation of adenylate cyclase activityGO:0045761100.479
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.477
positive regulation of kidney developmentGO:0090184280.475
uterus developmentGO:0060065160.475
negative regulation of molecular functionGO:00440922580.472
Human
cellular response to x rayGO:007148120.468
nephron epithelium morphogenesisGO:0072088680.468
regulation of intracellular transportGO:00323861590.467
prostate glandular acinus morphogenesisGO:006052670.463
kidney morphogenesisGO:0060993830.462
negative regulation of proteolysisGO:0045861740.458
regulation of endopeptidase activityGO:0052548890.457
fatty acid biosynthetic processGO:0006633410.454
protein localization to nucleusGO:00345041210.454
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.453
regulation of neurotransmitter levelsGO:0001505870.451
eating behaviorGO:0042755150.450
reactive oxygen species biosynthetic processGO:190340980.449
positive regulation of transcription from rna polymerase iii promoterGO:004594510.448
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.447
wound healingGO:00420601570.447
muscle cell differentiationGO:00426922610.443
positive regulation of lipid biosynthetic processGO:0046889180.442
protein localization to organelleGO:00333651850.442
myotube differentiationGO:00149021050.441
cellular response to lipopolysaccharideGO:0071222770.440
covalent chromatin modificationGO:00165691630.438
acetylcholine metabolic processGO:000829130.434
synaptic transmissionGO:00072683290.434
regulation of cell migrationGO:00303342190.434
monosaccharide biosynthetic processGO:0046364440.433
urogenital system developmentGO:00016552610.430
negative regulation of epithelial cell proliferation involved in prostate gland developmentGO:006077070.429
regulation of map kinase activityGO:00434051200.429
positive regulation of reactive oxygen species biosynthetic processGO:190342820.428
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.428
mesoderm structural organizationGO:004833810.427
positive regulation of lymphocyte proliferationGO:0050671700.426
positive regulation of cellular carbohydrate metabolic processGO:0010676290.424
regulation of histone acetylationGO:0035065190.419
skeletal muscle satellite cell maintenance involved in skeletal muscle regenerationGO:001483430.417
monocarboxylic acid transportGO:0015718440.417
negative regulation of fatty acid metabolic processGO:0045922100.417
regulation of the force of heart contractionGO:0002026170.410
cellular response to bile acidGO:190341310.409
mast cell proliferationGO:007066240.408
acute inflammatory responseGO:0002526410.407
response to estradiolGO:0032355120.405
Human Zebrafish Rat
positive regulation of protein serine threonine kinase activityGO:00719021060.402
regulation of peptidyl tyrosine phosphorylationGO:0050730930.402
regulation of calcidiol 1 monooxygenase activityGO:006055810.402
positive regulation of programmed cell deathGO:00430682180.401
internal protein amino acid acetylationGO:0006475420.397
cation homeostasisGO:00550802120.397
Rat
leukocyte differentiationGO:00025213420.396
axonogenesisGO:00074092740.392
regulation of cellular response to stressGO:00801351590.389
negative regulation of nervous system developmentGO:00519611560.389
positive regulation of t cell activationGO:00508701010.387
transcytosisGO:004505650.386
establishment of protein localization to organelleGO:00725941180.382
regulation of hormone biosynthetic processGO:004688590.380
hexose metabolic processGO:0019318980.380
transcription from rna polymerase iii promoterGO:000638330.379

Esr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
female reproductive system diseaseDOID:22900.983
disease of anatomical entityDOID:700.983
Human
reproductive system diseaseDOID:1500.983
prostate cancerDOID:1028300.827
male reproductive organ cancerDOID:385600.827
reproductive organ cancerDOID:19300.827
cancerDOID:16200.827
disease of cellular proliferationDOID:1456600.827
organ system cancerDOID:005068600.827
ovarian diseaseDOID:110000.649
bone remodeling diseaseDOID:008000500.412
bone diseaseDOID:008000100.412
musculoskeletal system diseaseDOID:1700.412
connective tissue diseaseDOID:6500.412