IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Cep78

centrosomal protein 78

(Aliases: D030027P05,5730599I05Rik)

Entrez: 208518
Ensembl: ENSMUSG00000041491
UniProtKB: Q6IRU7

Process Predictions
Disease Predictions

Cep78 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cellular response to dna damage stimulus	GO:0006974	207	0.147
dna metabolic process	GO:0006259	303	0.122
dna repair	GO:0006281	107	0.099
cellular amino acid metabolic process	GO:0006520	103	0.073
dna recombination	GO:0006310	92	0.066
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.054
microtubule based process	GO:0007017	236	0.053
cellular amine metabolic process	GO:0044106	44	0.052
regulation of cellular amino acid metabolic process	GO:0006521	5	0.052
regulation of cellular ketone metabolic process	GO:0010565	66	0.050
regulation of cellular amine metabolic process	GO:0033238	20	0.048
double strand break repair	GO:0006302	48	0.047
amine metabolic process	GO:0009308	45	0.041
cellular ketone metabolic process	GO:0042180	84	0.041
cellular nitrogen compound catabolic process	GO:0044270	280	0.038
nuclear division	GO:0000280	158	0.037
organelle fission	GO:0048285	170	0.036
microtubule cytoskeleton organization	GO:0000226	157	0.034
positive regulation of cellular amine metabolic process	GO:0033240	5	0.034
peptidyl amino acid modification	GO:0018193	336	0.033
regulation of histone h3 k36 methylation	GO:0000414	1	0.031
nucleobase containing small molecule metabolic process	GO:0055086	352	0.031
organic cyclic compound catabolic process	GO:1901361	295	0.029
ribonucleoside metabolic process	GO:0009119	245	0.029
heterocycle catabolic process	GO:0046700	280	0.028
glycosyl compound metabolic process	GO:1901657	246	0.028
regulation of organelle organization	GO:0033043	289	0.028
macromolecule methylation	GO:0043414	120	0.027
nucleoside phosphate metabolic process	GO:0006753	338	0.026
aromatic compound catabolic process	GO:0019439	286	0.026
nucleoside triphosphate catabolic process	GO:0009143	205	0.025
methylation	GO:0032259	134	0.025
purine nucleotide catabolic process	GO:0006195	211	0.024
ribonucleotide metabolic process	GO:0009259	291	0.024
nucleotide metabolic process	GO:0009117	332	0.024
meiotic nuclear division	GO:0007126	115	0.024
purine nucleotide metabolic process	GO:0006163	302	0.023
immune effector process	GO:0002252	321	0.023
apoptotic signaling pathway	GO:0097190	306	0.023
purine nucleoside metabolic process	GO:0042278	241	0.023
purine containing compound metabolic process	GO:0072521	311	0.023
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.023
cilium morphogenesis	GO:0060271	102	0.023
organelle assembly	GO:0070925	177	0.023
chromatin organization	GO:0006325	206	0.022
organonitrogen compound biosynthetic process	GO:1901566	192	0.022
purine nucleoside catabolic process	GO:0006152	205	0.022
purine ribonucleotide catabolic process	GO:0009154	208	0.022
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.022
nucleoside metabolic process	GO:0009116	246	0.021
cilium assembly	GO:0042384	81	0.021
nucleoside phosphate catabolic process	GO:1901292	222	0.020
organophosphate catabolic process	GO:0046434	232	0.020
chromatin modification	GO:0016568	187	0.020
nucleoside triphosphate metabolic process	GO:0009141	230	0.020
b cell activation	GO:0042113	161	0.020
meiotic cell cycle	GO:0051321	122	0.020
organonitrogen compound catabolic process	GO:1901565	264	0.020
male gamete generation	GO:0048232	285	0.020
purine ribonucleoside metabolic process	GO:0046128	241	0.020
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.020
purine ribonucleotide metabolic process	GO:0009150	290	0.020
organelle localization	GO:0051640	179	0.019
cellular component assembly involved in morphogenesis	GO:0010927	139	0.019
ribonucleotide catabolic process	GO:0009261	208	0.019
peptidyl lysine modification	GO:0018205	77	0.019
purine containing compound catabolic process	GO:0072523	213	0.019
somatic cell dna recombination	GO:0016444	51	0.019
glycosyl compound catabolic process	GO:1901658	206	0.019
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.019
leukocyte activation involved in immune response	GO:0002366	126	0.018
nucleotide catabolic process	GO:0009166	217	0.018
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.018
regulation of cell activation	GO:0050865	289	0.018
anatomical structure homeostasis	GO:0060249	145	0.018
skeletal system development	GO:0001501	356	0.018
production of molecular mediator of immune response	GO:0002440	103	0.018
somatic diversification of immune receptors	GO:0002200	53	0.018
meiotic cell cycle process	GO:1903046	77	0.018
carbohydrate derivative catabolic process	GO:1901136	231	0.017
meiosis i	GO:0007127	60	0.017
ribonucleoside catabolic process	GO:0042454	206	0.017
positive regulation of protein modification process	GO:0031401	299	0.017
ribose phosphate metabolic process	GO:0019693	291	0.017
carbohydrate derivative biosynthetic process	GO:1901137	183	0.016
purine ribonucleoside catabolic process	GO:0046130	205	0.016
cell activation involved in immune response	GO:0002263	126	0.016
somatic diversification of immune receptors via germline recombination within a single locus	GO:0002562	51	0.016
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.016
response to radiation	GO:0009314	165	0.016
regulation of membrane potential	GO:0042391	192	0.016
immunoglobulin production	GO:0002377	73	0.016
leukocyte mediated immunity	GO:0002443	174	0.016
regulation of antimicrobial humoral response	GO:0002759	3	0.016
regulation of cell cycle	GO:0051726	281	0.016
small gtpase mediated signal transduction	GO:0007264	97	0.016
negative regulation of cellular component organization	GO:0051129	194	0.016
somatic recombination of immunoglobulin gene segments	GO:0016447	42	0.016
regulation of lymphocyte activation	GO:0051249	240	0.016
regulation of cellular response to stress	GO:0080135	159	0.015
protein modification by small protein conjugation or removal	GO:0070647	207	0.015
spermatogenesis	GO:0007283	284	0.015
positive regulation of programmed cell death	GO:0043068	218	0.015
protein alkylation	GO:0008213	81	0.015
covalent chromatin modification	GO:0016569	163	0.015
oxidation reduction process	GO:0055114	342	0.015
histone modification	GO:0016570	159	0.014
germ cell development	GO:0007281	185	0.014
regulation of cellular component biogenesis	GO:0044087	181	0.014
mitotic cell cycle	GO:0000278	195	0.014
cellular lipid metabolic process	GO:0044255	323	0.014
positive regulation of organelle organization	GO:0010638	128	0.014
ras protein signal transduction	GO:0007265	77	0.014
synapsis	GO:0007129	34	0.014
cation transport	GO:0006812	399	0.014
establishment of organelle localization	GO:0051656	122	0.014
macromolecule catabolic process	GO:0009057	281	0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.013
regulation of dna recombination	GO:0000018	34	0.013
positive regulation of lymphocyte activation	GO:0051251	140	0.013
cytoplasmic transport	GO:0016482	234	0.013
membrane organization	GO:0061024	245	0.013
protein methylation	GO:0006479	81	0.013
positive regulation of cell activation	GO:0050867	158	0.013
protein modification by small protein conjugation	GO:0032446	187	0.013
nitrogen compound transport	GO:0071705	271	0.013
lymphocyte activation involved in immune response	GO:0002285	93	0.013
response to light stimulus	GO:0009416	135	0.013
male meiosis	GO:0007140	37	0.012
lymphocyte mediated immunity	GO:0002449	139	0.012
posttranscriptional regulation of gene expression	GO:0010608	155	0.012
maintenance of location	GO:0051235	89	0.012
spermatid development	GO:0007286	108	0.012
regulation of antimicrobial peptide biosynthetic process	GO:0002805	1	0.012
positive regulation of cell death	GO:0010942	224	0.012
b cell mediated immunity	GO:0019724	71	0.012
negative regulation of protein metabolic process	GO:0051248	282	0.012
multicellular organismal signaling	GO:0035637	91	0.012
protein ubiquitination	GO:0016567	171	0.012
nucleoside monophosphate metabolic process	GO:0009123	85	0.012
skin development	GO:0043588	220	0.012
somatic diversification of immunoglobulins	GO:0016445	43	0.012
nucleoside catabolic process	GO:0009164	206	0.012
cellular macromolecule catabolic process	GO:0044265	206	0.012
immunoglobulin mediated immune response	GO:0016064	69	0.012
intrinsic apoptotic signaling pathway	GO:0097193	132	0.012
protein maturation	GO:0051604	176	0.012
action potential	GO:0001508	78	0.012
cell type specific apoptotic process	GO:0097285	268	0.012
transmembrane transport	GO:0055085	412	0.011
adaptive immune response	GO:0002250	155	0.011
reactive nitrogen species metabolic process	GO:2001057	0	0.011
camera type eye development	GO:0043010	266	0.011
transmission of nerve impulse	GO:0019226	76	0.011
positive regulation of immune effector process	GO:0002699	107	0.011
regulation of apoptotic signaling pathway	GO:2001233	197	0.011
sensory perception	GO:0007600	245	0.011
leukocyte differentiation	GO:0002521	342	0.011
connective tissue development	GO:0061448	179	0.011
immunoglobulin production involved in immunoglobulin mediated immune response	GO:0002381	43	0.011
regulation of chromosome organization	GO:0033044	83	0.011
intracellular protein transport	GO:0006886	204	0.011
regulation of multi organism process	GO:0043900	111	0.011
positive regulation of apoptotic process	GO:0043065	217	0.011
response to organonitrogen compound	GO:0010243	246	0.011
reactive oxygen species metabolic process	GO:0072593	84	0.011
protein acylation	GO:0043543	64	0.011
stem cell differentiation	GO:0048863	268	0.011
regulation of chromatin silencing	GO:0031935	2	0.011
cation transmembrane transport	GO:0098655	266	0.010
regulation of purine nucleotide metabolic process	GO:1900542	169	0.010
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.010
sensory organ morphogenesis	GO:0090596	242	0.010
forebrain development	GO:0030900	302	0.010
histone lysine methylation	GO:0034968	50	0.010
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.010
regulation of b cell activation	GO:0050864	81	0.010
t cell activation	GO:0042110	289	0.010
carbohydrate metabolic process	GO:0005975	230	0.010
regulation of mapk cascade	GO:0043408	248	0.010
dna replication	GO:0006260	52	0.010
lateral inhibition	GO:0046331	1	0.010
mitotic cell cycle process	GO:1903047	159	0.010
isotype switching	GO:0045190	36	0.010
regionalization	GO:0003002	337	0.010
negative regulation of dna replication	GO:0008156	4	0.010
negative regulation of cell proliferation	GO:0008285	296	0.010
atp catabolic process	GO:0006200	55	0.010
nuclear transport	GO:0051169	139	0.010

Cep78 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.029
disease of anatomical entity	DOID:7	0.029
immune system disease	DOID:2914	0.026
hematopoietic system disease	DOID:74	0.026
organ system cancer	DOID:0050686	0.018
disease of cellular proliferation	DOID:14566	0.018
cancer	DOID:162	0.018
congenital hypoplastic anemia	DOID:1342	0.014
aplastic anemia	DOID:12449	0.014
anemia	DOID:2355	0.014
bone marrow disease	DOID:4961	0.014
musculoskeletal system disease	DOID:17	0.013
neurodegenerative disease	DOID:1289	0.011
central nervous system disease	DOID:331	0.011
sensory system disease	DOID:0050155	0.010

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