Mus musculus

0 known processes

Topbp1

topoisomerase (DNA) II binding protein 1

(Aliases: 2810429C13Rik,1110031N14Rik,D430026L04Rik,mKIAA0259,AI256758)

Topbp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna conformation changeGO:0071103370.661
meiosis iGO:0007127600.602
dna repairGO:00062811070.497
synapsisGO:0007129340.477
dna metabolic processGO:00062593030.463
Worm
cellular response to dna damage stimulusGO:00069742070.453
Human Worm Fly
nuclear transportGO:00511691390.321
meiotic cell cycleGO:00513211220.318
meiotic cell cycle processGO:1903046770.271
chromosome organization involved in meiosisGO:0070192390.266
negative regulation of cell cycleGO:00457861230.246
Fly
microtubule based processGO:00070172360.242
recombinational repairGO:0000725210.234
nucleic acid transportGO:0050657180.208
gene silencingGO:0016458380.205
mitotic cell cycle processGO:19030471590.204
Fly
cytoplasmic transportGO:00164822340.201
chromatin organizationGO:00063252060.176
mrna transportGO:0051028130.171
regulation of hydrolase activityGO:00513362460.169
rna transportGO:0050658180.153
double strand break repairGO:0006302480.152
nucleocytoplasmic transportGO:00069131390.143
intracellular protein transportGO:00068862040.137
protein import into nucleusGO:0006606950.133
regulation of cell cycleGO:00517262810.133
Fly
dna packagingGO:0006323300.123
protein localization to nucleusGO:00345041210.119
posttranscriptional gene silencingGO:0016441100.118
organelle fissionGO:00482851700.115
protein targetingGO:00066051430.110
cell cycle checkpointGO:0000075470.109
Fly
establishment of rna localizationGO:0051236180.099
gonad developmentGO:00084061410.099
dna recombinationGO:0006310920.096
nitrogen compound transportGO:00717052710.094
regulation of cell cycle processGO:00105641600.094
Fly
single organism nuclear importGO:1902593950.094
nuclear exportGO:0051168340.088
base excision repairGO:000628490.084
mitotic cell cycleGO:00002781950.078
Fly
nucleobase containing compound transportGO:0015931270.077
mitotic chromosome condensationGO:000707610.076
chromatin modificationGO:00165681870.074
macromolecule methylationGO:00434141200.069
mitotic cell cycle checkpointGO:0007093310.066
Fly
nuclear divisionGO:00002801580.066
macromolecule catabolic processGO:00090572810.065
positive regulation of nfat protein import into nucleusGO:005153310.064
rna localizationGO:0006403230.064
negative regulation of mitotic cell cycle phase transitionGO:1901991450.063
Fly
chromatin assemblyGO:0031497130.062
mitotic nuclear divisionGO:0007067480.061
gene silencing by rnaGO:0031047190.060
protein localization to organelleGO:00333651850.058
peptidyl amino acid modificationGO:00181933360.058
regulation of organelle organizationGO:00330432890.054
methylationGO:00322591340.054
nuclear importGO:0051170950.052
protein importGO:00170381010.052
cellular nitrogen compound catabolic processGO:00442702800.050
protein complex disassemblyGO:0043241400.049
forebrain developmentGO:00309003020.049
mitotic sister chromatid segregationGO:0000070140.047
cellular macromolecule catabolic processGO:00442652060.047
chromatin assembly or disassemblyGO:0006333160.047
establishment of protein localization to organelleGO:00725941180.046
double strand break repair via homologous recombinationGO:0000724210.046
positive regulation of hydrolase activityGO:00513451480.046
regulation of nucleocytoplasmic transportGO:0046822730.046
male gamete generationGO:00482322850.045
positive regulation of nucleocytoplasmic transportGO:0046824300.045
negative regulation of cellular component organizationGO:00511291940.044
regulation of protein transportGO:00512231630.044
regulation of cell cycle phase transitionGO:1901987770.043
Fly
negative regulation of cellular protein metabolic processGO:00322692470.043
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.042
female meiotic divisionGO:0007143210.041
development of primary sexual characteristicsGO:00451371430.041
regulation of multi organism processGO:00439001110.040
rna interferenceGO:001624620.040
regulation of mitotic cell cycleGO:00073461260.040
Fly
small gtpase mediated signal transductionGO:0007264970.038
regulation of mitotic cell cycle phase transitionGO:1901990730.036
Fly
negative regulation of cell cycle processGO:0010948690.036
Fly
spermatogenesisGO:00072832840.036
posttranscriptional regulation of gene expressionGO:00106081550.034
protein modification by small protein conjugation or removalGO:00706472070.034
dna endoreduplicationGO:004202340.034
kinetochore organizationGO:005138320.034
regulation of cytoplasmic transportGO:19036491120.033
spermatid differentiationGO:00485151150.033
heterocycle catabolic processGO:00467002800.033
meiotic nuclear divisionGO:00071261150.032
positive regulation of programmed cell deathGO:00430682180.032
cell type specific apoptotic processGO:00972852680.030
organelle assemblyGO:00709251770.029
mitotic recombinationGO:000631230.029
ribonucleoside metabolic processGO:00091192450.029
regulation of centriole replicationGO:004659910.029
mrna export from nucleusGO:0006406110.028
maintenance of locationGO:0051235890.028
cellular response to hormone stimulusGO:00328701500.027
positive regulation of intracellular transportGO:0032388700.027
cellular amine metabolic processGO:0044106440.027
nucleus organizationGO:0006997450.027
centromere complex assemblyGO:003450830.027
cellular amino acid metabolic processGO:00065201030.027
dendrite developmentGO:00163581150.027
sister chromatid segregationGO:0000819200.026
spindle organizationGO:0007051280.026
response to organic cyclic compoundGO:00140701980.025
histone modificationGO:00165701590.025
response to growth factorGO:00708481980.025
negative regulation of mitotic cell cycleGO:0045930580.025
Fly
mitotic g2 dna damage checkpointGO:000709580.025
Fly
dna methylationGO:0006306430.024
regulation of intracellular protein transportGO:0033157820.024
interspecies interaction between organismsGO:0044419830.024
reciprocal dna recombinationGO:0035825160.024
negative regulation of multi organism processGO:0043901680.024
protein maturationGO:00516041760.023
nucleobase containing small molecule metabolic processGO:00550863520.023
regulation of neuron deathGO:19012141340.023
intra s dna damage checkpointGO:003157340.023
double strand break repair via nonhomologous end joiningGO:0006303100.023
positive regulation of protein transportGO:0051222930.023
regulation of purine nucleotide catabolic processGO:00331211220.023
endocytosisGO:00068971680.023
regulation of establishment of protein localizationGO:00702011810.022
compound eye developmentGO:004874910.022
regulation of cellular amine metabolic processGO:0033238200.021
protein modification by small protein removalGO:0070646210.021
cell fate commitmentGO:00451652100.021
regulation of meiosis iGO:006063170.021
negative regulation of synapse assemblyGO:005196430.021
cellular response to growth factor stimulusGO:00713631970.021
chromosome segregationGO:0007059480.021
heterochromatin organizationGO:007082840.020
posttranscriptional gene silencing by rnaGO:0035194100.020
anatomical structure homeostasisGO:00602491450.020
dna replicationGO:0006260520.020
Worm
developmental cell growthGO:0048588840.020
regulation of protein targetingGO:1903533610.020
axonogenesisGO:00074092740.019
chromatin remodeling at centromereGO:003105520.019
microtubule organizing center organizationGO:0031023280.019
negative regulation of phagocytosisGO:005076540.019
regulation of cellular catabolic processGO:00313292420.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.019
dna alkylationGO:0006305430.019
germ cell developmentGO:00072811850.019
digestive system developmentGO:00551232000.019
cellular protein catabolic processGO:00442571550.019
dna dependent dna replicationGO:0006261240.018
neuron projection extensionGO:1990138640.018
ribonucleoprotein complex localizationGO:007116610.018
histone mrna metabolic processGO:000833430.018
homeostasis of number of cellsGO:00488722100.018
positive regulation of protein modification processGO:00314012990.018
regulation of microtubule based processGO:0032886520.018
viral processGO:0016032410.018
positive regulation of cell deathGO:00109422240.017
hematopoietic progenitor cell differentiationGO:00022441430.017
cellular ketone metabolic processGO:0042180840.017
receptor mediated endocytosisGO:0006898510.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
ras protein signal transductionGO:0007265770.016
microtubule cytoskeleton organizationGO:00002261570.016
cellular response to transforming growth factor beta stimulusGO:0071560880.016
camera type eye developmentGO:00430102660.016
lung developmentGO:00303241640.016
male gonad developmentGO:0008584880.015
neuron migrationGO:00017641220.015
nuclear transcribed mrna catabolic processGO:0000956160.015
regulation of cellular amino acid metabolic processGO:000652150.015
dna damage checkpointGO:0000077260.015
Fly
nucleoside metabolic processGO:00091162460.015
organophosphate catabolic processGO:00464342320.015
establishment of organelle localizationGO:00516561220.015
transcription factor import into nucleusGO:0042991260.015
aromatic compound catabolic processGO:00194392860.015
negative regulation of b cell differentiationGO:004557840.015
regulation of protein localizationGO:00328802310.015
rna export from nucleusGO:0006405150.015
chromatin remodelingGO:0006338320.014
positive regulation of peptidase activityGO:0010952490.014
amine metabolic processGO:0009308450.014
purine nucleoside metabolic processGO:00422782410.014
regulation of endopeptidase activityGO:0052548890.014
protein processingGO:00164851630.014
dna replication checkpointGO:000007620.014
Fly
cell divisionGO:00513011200.014
regulation of cellular ketone metabolic processGO:0010565660.014
ribonucleotide metabolic processGO:00092592910.014
centrosome organizationGO:0051297260.014
regulation of ras protein signal transductionGO:00465781140.014
regulation of protein import into nucleusGO:0042306520.014
regulation of nuclear divisionGO:0051783560.014
positive regulation of nucleoside metabolic processGO:0045979910.014
synaptonemal complex organizationGO:0070193150.014
organonitrogen compound biosynthetic processGO:19015661920.014
negative regulation of neuron deathGO:1901215980.013
synaptonemal complex assemblyGO:0007130130.013
non recombinational repairGO:0000726100.013
regulation of apoptotic signaling pathwayGO:20012331970.013
g1 s transition of mitotic cell cycleGO:0000082570.013
negative regulation of organelle organizationGO:0010639900.013
regulation of neuron apoptotic processGO:00435231220.013
engulfment of apoptotic cellGO:004365230.013
neural precursor cell proliferationGO:00613511210.013
dna modificationGO:0006304500.013
humoral immune responseGO:0006959570.013
chemotaxisGO:00069352470.013
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.013
purine ribonucleoside metabolic processGO:00461282410.013
cellular response to organonitrogen compoundGO:00714171450.013
regulation of cell cycle g1 s phase transitionGO:1902806350.013
respiratory tube developmentGO:00303231670.013
negative regulation of protein metabolic processGO:00512482820.013
cellular protein complex disassemblyGO:0043624360.013
regulation of chromatin modificationGO:1903308570.012
spermatid developmentGO:00072861080.012
response to oxidative stressGO:00069791230.012
positive regulation of cell developmentGO:00107202370.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
respiratory system developmentGO:00605411900.012
definitive hemopoiesisGO:0060216200.012
response to inorganic substanceGO:0010035960.012
innate immune responseGO:00450871570.012
neuron apoptotic processGO:00514021420.012
regulation of dna endoreduplicationGO:003287530.012
regulation of protein complex disassemblyGO:0043244280.012
positive regulation of gtp catabolic processGO:0033126850.012
nucleoside phosphate metabolic processGO:00067533380.012
antimicrobial peptide productionGO:000277520.012
regulation of exit from mitosisGO:000709610.012
purine containing compound metabolic processGO:00725213110.012
ear developmentGO:00435832000.012
heterochromatin assemblyGO:003150720.012
proteasomal protein catabolic processGO:0010498980.012
regulation of cell activationGO:00508652890.011
viral life cycleGO:0019058360.011
regulation of meiotic cell cycleGO:0051445340.011
neuron deathGO:00709971540.011
negative regulation of cell cycle phase transitionGO:1901988480.011
Fly
striated muscle contractionGO:0006941450.011
protein modification by small protein conjugationGO:00324461870.011
ribose phosphate metabolic processGO:00196932910.011
epidermis developmentGO:00085441870.011
positive regulation of nucleotide metabolic processGO:00459811140.011
regulation of peptidase activityGO:0052547960.011
regulation of protein localization to nucleusGO:1900180600.011
positive regulation of apoptotic processGO:00430652170.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
organic hydroxy compound metabolic processGO:19016152030.011
telencephalon developmentGO:00215371860.011
negative regulation of chromatin silencingGO:003193610.011
regulation of neuron projection developmentGO:00109751690.011
developmental growth involved in morphogenesisGO:00605601380.011
symbiosis encompassing mutualism through parasitismGO:0044403830.011
positive regulation of nucleotide catabolic processGO:0030813880.011
reciprocal meiotic recombinationGO:0007131160.010
positive regulation of intracellular protein transportGO:0090316420.010
fertilizationGO:00095661270.010
regulation of cellular response to growth factor stimulusGO:0090287820.010
axon guidanceGO:00074111410.010
regulation of kinase activityGO:00435492490.010
regulation of cytoskeleton organizationGO:00514931220.010
organonitrogen compound catabolic processGO:19015652640.010
apoptotic signaling pathwayGO:00971903060.010
regulation of nucleotide metabolic processGO:00061401690.010

Topbp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org