Mus musculus

38 known processes

Alpl

alkaline phosphatase, liver/bone/kidney

(Aliases: APTNAP,Akp-2,TNSALP,Akp2,TNAP)

Alpl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory organ morphogenesisGO:00905962420.273
cell adhesionGO:00071553290.186
urogenital system developmentGO:00016552610.174
cellular amino acid metabolic processGO:00065201030.168
epithelial tube morphogenesisGO:00605623030.153
gland developmentGO:00487323300.150
regulation of cellular amine metabolic processGO:0033238200.141
skin developmentGO:00435882200.140
positive regulation of cellular amine metabolic processGO:003324050.139
ion transmembrane transportGO:00342203610.136
apoptotic signaling pathwayGO:00971903060.134
cellular response to growth factor stimulusGO:00713631970.132
regulation of cellular ketone metabolic processGO:0010565660.129
regulation of cellular amino acid metabolic processGO:000652150.128
cellular ion homeostasisGO:00068731650.124
camera type eye developmentGO:00430102660.121
negative regulation of molecular functionGO:00440922580.119
cellular amine metabolic processGO:0044106440.118
renal system developmentGO:00720012250.118
cell substrate adhesionGO:00315891300.116
amine metabolic processGO:0009308450.115
positive regulation of cellular amino acid metabolic processGO:004576430.115
forebrain developmentGO:00309003020.113
cation transportGO:00068123990.111
cellular ketone metabolic processGO:0042180840.111
transmembrane transportGO:00550854120.108
skeletal system developmentGO:00015013560.107
cell type specific apoptotic processGO:00972852680.107
appendage developmentGO:00487361660.101
anion transportGO:00068201770.101
myeloid cell differentiationGO:00300992330.100
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.100
kidney developmentGO:00018222130.099
positive regulation of cell developmentGO:00107202370.098
spermatogenesisGO:00072832840.095
retina development in camera type eyeGO:00600411190.090
branching morphogenesis of an epithelial tubeGO:00487541590.088
neuron deathGO:00709971540.088
heart morphogenesisGO:00030071780.084
fat cell differentiationGO:00454441600.080
stem cell differentiationGO:00488632680.080
muscle cell differentiationGO:00426922610.080
ossificationGO:00015032160.080
divalent metal ion transportGO:00708381720.078
regulation of establishment of protein localizationGO:00702011810.077
cellular chemical homeostasisGO:00550822150.077
embryonic organ morphogenesisGO:00485622760.075
cation homeostasisGO:00550802120.075
limb developmentGO:00601731660.073
extrinsic apoptotic signaling pathwayGO:00971911260.071
peptidyl amino acid modificationGO:00181933360.070
connective tissue developmentGO:00614481790.067
regulation of protein localizationGO:00328802310.067
protein import into nucleusGO:0006606950.065
embryonic skeletal system developmentGO:00487061200.064
renal system processGO:0003014480.064
embryonic epithelial tube formationGO:00018381300.063
regulation of cell motilityGO:20001452360.063
intracellular protein transportGO:00068862040.061
morphogenesis of a branching structureGO:00017632030.061
placenta developmentGO:00018901400.061
male gamete generationGO:00482322850.060
positive regulation of protein modification processGO:00314012990.060
regulation of membrane potentialGO:00423911920.060
synaptic transmissionGO:00072683290.059
mapk cascadeGO:00001652810.059
organic anion transportGO:00157111370.059
calcium ion homeostasisGO:00550741270.059
protein targetingGO:00066051430.059
cellular homeostasisGO:00197252400.058
cellular lipid metabolic processGO:00442553230.058
eye photoreceptor cell differentiationGO:0001754410.058
regulation of ion transmembrane transportGO:00347651190.058
multicellular organismal homeostasisGO:00488711640.057
ras protein signal transductionGO:0007265770.057
protein localization to nucleusGO:00345041210.057
regulation of body fluid levelsGO:00508781620.057
regulation of neuron deathGO:19012141340.056
odontogenesisGO:0042476780.054
cation transmembrane transportGO:00986552660.054
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.053
striated muscle tissue developmentGO:00147062930.052
cellular response to organonitrogen compoundGO:00714171450.052
regulation of cell adhesionGO:00301551540.051
negative regulation of cell developmentGO:00107211690.051
regulation of hormone levelsGO:00108172110.051
extracellular matrix organizationGO:00301981470.051
regulation of cell substrate adhesionGO:0010810730.051
oxidation reduction processGO:00551143420.051
hematopoietic progenitor cell differentiationGO:00022441430.050
organic hydroxy compound transportGO:0015850930.050
transmission of nerve impulseGO:0019226760.050
regulation of protein kinase activityGO:00458592320.049
single organism cell adhesionGO:00986021560.049
sensory perceptionGO:00076002450.049
carbohydrate metabolic processGO:00059752300.049
development of primary sexual characteristicsGO:00451371430.049
regulation of intracellular transportGO:00323861590.048
cellular response to lipidGO:00713961450.048
negative regulation of intracellular signal transductionGO:19025321670.048
lipid biosynthetic processGO:00086101790.048
morphogenesis of a branching epitheliumGO:00611381930.047
regulation of ossificationGO:00302781120.047
establishment of protein localization to organelleGO:00725941180.047
cellular divalent inorganic cation homeostasisGO:00725031270.046
locomotory behaviorGO:00076261950.046
regulation of cell migrationGO:00303342190.046
positive regulation of protein phosphorylationGO:00019342420.046
organic acid transportGO:00158491010.046
stem cell developmentGO:00488642190.046
embryonic placenta developmentGO:0001892980.045
neuronal action potentialGO:0019228540.044
cellular metal ion homeostasisGO:00068751510.044
regulation of epithelial cell proliferationGO:00506781410.044
gonad developmentGO:00084061410.044
cell matrix adhesionGO:0007160680.044
regulation of apoptotic signaling pathwayGO:20012331970.043
regulation of system processGO:00440572000.043
morphogenesis of embryonic epitheliumGO:00163311590.043
nitrogen compound transportGO:00717052710.043
metal ion homeostasisGO:00550651890.042
muscle tissue developmentGO:00605373080.042
appendage morphogenesisGO:00351071490.042
regionalizationGO:00030023370.042
cellular carbohydrate metabolic processGO:00442621190.042
protein localization to organelleGO:00333651850.042
neural tube developmentGO:00219151600.041
Mouse
regulation of anatomical structure sizeGO:00900661780.041
chemotaxisGO:00069352470.041
energy derivation by oxidation of organic compoundsGO:0015980770.041
cellular modified amino acid metabolic processGO:0006575630.041
pallium developmentGO:00215431200.040
angiogenesisGO:00015252010.040
regulation of cellular carbohydrate metabolic processGO:0010675750.040
axonogenesisGO:00074092740.039
regulation of endopeptidase activityGO:0052548890.039
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.039
divalent inorganic cation homeostasisGO:00725071380.038
ear morphogenesisGO:00424711180.038
negative regulation of cellular protein metabolic processGO:00322692470.037
tissue homeostasisGO:00018941150.037
exocytosisGO:00068871210.037
axon ensheathmentGO:0008366760.037
regulation of secretionGO:00510462740.037
developmental maturationGO:00217001930.036
generation of precursor metabolites and energyGO:00060911030.036
positive regulation of protein serine threonine kinase activityGO:00719021060.036
protein maturationGO:00516041760.036
epidermis developmentGO:00085441870.036
small gtpase mediated signal transductionGO:0007264970.036
blood vessel morphogenesisGO:00485142850.036
negative regulation of neuron apoptotic processGO:0043524920.035
amide transportGO:00428861380.035
positive regulation of cell migrationGO:00303351090.035
regulation of metal ion transportGO:00109591060.035
negative regulation of cell proliferationGO:00082852960.035
divalent inorganic cation transportGO:00725111780.035
regulation of protein transportGO:00512231630.035
cellular calcium ion homeostasisGO:00068741190.034
hexose metabolic processGO:0019318980.034
regulation of bmp signaling pathwayGO:0030510600.034
peptide transportGO:00158331330.034
skeletal system morphogenesisGO:00487052030.033
response to radiationGO:00093141650.033
extracellular structure organizationGO:00430621480.033
regulation of circadian rhythmGO:0042752580.033
bone developmentGO:00603481200.033
glucan metabolic processGO:0044042320.033
molting cycleGO:0042303900.033
inner ear morphogenesisGO:00424721010.033
positive regulation of growthGO:00459271040.032
immune effector processGO:00022523210.032
response to organic cyclic compoundGO:00140701980.032
epithelial cell proliferationGO:00506731740.032
positive regulation of mapk cascadeGO:00434101700.032
cell fate commitmentGO:00451652100.032
glucose homeostasisGO:00425931280.032
hormone metabolic processGO:0042445860.032
lung developmentGO:00303241640.031
ear developmentGO:00435832000.031
positive regulation of protein kinase activityGO:00458601440.031
trunk neural crest cell migrationGO:003648440.031
epithelial cell developmentGO:00020641590.031
nephron developmentGO:00720061090.031
glycerolipid metabolic processGO:00464861220.031
cognitionGO:00508901490.031
acetate ester transportGO:190137420.031
regulation of protein targetingGO:1903533610.031
cellular response to peptide hormone stimulusGO:0071375920.031
regulation of neuron apoptotic processGO:00435231220.031
regulation of homeostatic processGO:00328441820.030
regulation of kinase activityGO:00435492490.030
cell chemotaxisGO:0060326810.030
activation of adenylate cyclase activityGO:000719040.030
tissue remodelingGO:00487711020.030
mitotic cell cycleGO:00002781950.030
diencephalon developmentGO:0021536630.030
muscle cell developmentGO:00550011330.030
sodium ion transportGO:0006814730.030
regulation of proteolysisGO:00301621640.029
embryonic skeletal system morphogenesisGO:0048704910.029
organ growthGO:00352651170.029
inflammatory responseGO:00069542440.029
action potentialGO:0001508780.029
negative regulation of neuron deathGO:1901215980.029
lipid transportGO:0006869980.029
limb morphogenesisGO:00351081490.029
regulation of glucose metabolic processGO:0010906600.029
carboxylic acid transportGO:00469421000.029
positive regulation of cell adhesionGO:0045785800.029
glycoprotein metabolic processGO:00091001160.029
hair cycleGO:0042633900.029
stem cell maintenanceGO:00198271300.029
negative regulation of cellular component organizationGO:00511291940.028
neural tube formationGO:00018411080.028
regulation of cell growthGO:0001558910.028
retina morphogenesis in camera type eyeGO:0060042450.028
metanephros developmentGO:0001656790.028
organelle localizationGO:00516401790.028
cell junction organizationGO:0034330770.028
regulation of organelle organizationGO:00330432890.028
mesonephric tubule developmentGO:0072164940.028
cerebral cortex developmentGO:0021987860.027
telencephalon developmentGO:00215371860.027
monocarboxylic acid metabolic processGO:00327871910.027
developmental cell growthGO:0048588840.027
cytokine productionGO:00018163190.027
regulation of cell projection organizationGO:00313442060.027
regulation of transmembrane transportGO:00347621280.027
regulation of ion transportGO:00432692150.027
kidney epithelium developmentGO:00720731210.027
nephron epithelium developmentGO:0072009920.027
protein importGO:00170381010.027
response to temperature stimulusGO:0009266550.026
meiotic cell cycleGO:00513211220.026
negative regulation of protein metabolic processGO:00512482820.026
cellular amide metabolic processGO:0043603580.026
cytoplasmic transportGO:00164822340.026
protein processingGO:00164851630.026
negative regulation of phosphate metabolic processGO:00459361840.026
inorganic anion transportGO:0015698430.026
negative regulation of cellular amine metabolic processGO:003323910.026
positive regulation of nervous system developmentGO:00519622210.026
lens development in camera type eyeGO:0002088620.026
axon guidanceGO:00074111410.026
lipid localizationGO:00108761260.026
regulation of lipid metabolic processGO:00192161180.026
embryonic limb morphogenesisGO:00303261260.026
response to inorganic substanceGO:0010035960.026
endomembrane system organizationGO:00102561470.025
renal tubule developmentGO:0061326870.025
epithelial cell migrationGO:0010631630.025
regulation of cellular response to stressGO:00801351590.025
nucleocytoplasmic transportGO:00069131390.025
organophosphate biosynthetic processGO:00904071220.025
monocarboxylic acid transportGO:0015718440.025
organelle fissionGO:00482851700.025
negative regulation of cell motilityGO:2000146610.025
t cell activationGO:00421102890.025
cardiac chamber morphogenesisGO:0003206930.025
organonitrogen compound biosynthetic processGO:19015661920.025
myeloid leukocyte differentiationGO:00025731190.025
regulation of cell activationGO:00508652890.024
monosaccharide metabolic processGO:00059961060.024
central nervous system neuron differentiationGO:00219531620.024
cellular glucan metabolic processGO:0006073320.024
skeletal muscle organ developmentGO:00605381630.024
t cell differentiationGO:00302171740.024
membrane organizationGO:00610242450.024
regulation of cytoplasmic transportGO:19036491120.024
cellular response to insulin stimulusGO:0032869780.024
cellular response to cytokine stimulusGO:00713451890.024
peptidyl tyrosine modificationGO:00182121450.024
purine containing compound metabolic processGO:00725213110.024
cell growthGO:00160491300.024
vascular process in circulatory systemGO:0003018620.024
regulation of cysteine type endopeptidase activityGO:2000116650.024
limbic system developmentGO:0021761720.024
regulation of mapk cascadeGO:00434082480.024
synapse organizationGO:00508081250.024
response to light stimulusGO:00094161350.024
regulation of cellular component biogenesisGO:00440871810.023
plasma membrane organizationGO:0007009900.023
renal sodium ion transportGO:000309620.023
respiratory tube developmentGO:00303231670.023
nephron tubule developmentGO:0072080840.023
circulatory system processGO:00030131970.023
regulation of transferase activityGO:00513382630.023
cartilage developmentGO:00512161400.023
response to acid chemicalGO:00011011110.023
carbohydrate derivative biosynthetic processGO:19011371830.023
nuclear transportGO:00511691390.023
nuclear importGO:0051170950.023
regulation of intracellular protein transportGO:0033157820.023
regulation of carbohydrate metabolic processGO:0006109750.023
nucleobase containing small molecule metabolic processGO:00550863520.023
positive regulation of cell deathGO:00109422240.023
response to growth factorGO:00708481980.023
regulation of protein import into nucleusGO:0042306520.023
negative regulation of neuron differentiationGO:00456651010.023
regulation of secretion by cellGO:19035302490.023
phosphatidylinositol mediated signalingGO:0048015410.023
developmental growth involved in morphogenesisGO:00605601380.023
actin filament organizationGO:00070151130.023
negative regulation of protein modification processGO:00314001630.023
neuron apoptotic processGO:00514021420.023
epithelium migrationGO:0090132630.023
brown fat cell differentiationGO:0050873360.023
negative regulation of phosphorus metabolic processGO:00105631840.022
carboxylic acid biosynthetic processGO:0046394860.022
nuclear divisionGO:00002801580.022
leukocyte differentiationGO:00025213420.022
epithelial tube formationGO:00721751300.022
maintenance of locationGO:0051235890.022
nucleoside phosphate metabolic processGO:00067533380.022
developmental programmed cell deathGO:0010623410.022
neural crest cell developmentGO:0014032480.022
sympathetic neuron projection guidanceGO:009749140.022
ureteric bud developmentGO:0001657940.022
mesonephric epithelium developmentGO:0072163940.022
regulation of peptidase activityGO:0052547960.022
respiratory system developmentGO:00605411900.022
regulation of ras protein signal transductionGO:00465781140.022
regulation of cytokine productionGO:00018172660.022
posttranscriptional regulation of gene expressionGO:00106081550.022
lymphocyte differentiationGO:00300982420.022
regulation of chloride transportGO:200122520.022
sensory perception of mechanical stimulusGO:00509541070.021
photoreceptor cell differentiationGO:0046530520.021
trunk segmentationGO:003529040.021
regulation of peptide hormone secretionGO:0090276750.021
inorganic ion transmembrane transportGO:00986602340.021
anatomical structure homeostasisGO:00602491450.021
phosphatidylinositol 3 kinase signalingGO:0014065360.021
response to insulinGO:00328681000.021
response to organonitrogen compoundGO:00102432460.021
mesenchyme developmentGO:00604851520.021
regulation of hippo signalingGO:003533010.021
cell maturationGO:00484691270.021
erk1 and erk2 cascadeGO:0070371770.021
lipid modificationGO:0030258650.021
response to peptide hormoneGO:00434341270.021
cellular response to peptideGO:1901653920.021
regulation of synaptic plasticityGO:0048167870.021
heart contractionGO:0060047930.021
organic hydroxy compound metabolic processGO:19016152030.021
mitotic cell cycle processGO:19030471590.021
regulation of circadian sleep wake cycle sleepGO:004518730.021
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.021
regulation of cellular catabolic processGO:00313292420.021
tube formationGO:00351481400.020
regulation of sequence specific dna binding transcription factor activityGO:00510901060.020
actin cytoskeleton organizationGO:00300362200.020
development of primary male sexual characteristicsGO:0046546880.020
regulation of circadian sleep wake cycleGO:004274930.020
carbohydrate homeostasisGO:00335001280.020
regulation of synaptic growth at neuromuscular junctionGO:000858240.020
establishment of endothelial blood brain barrierGO:001404530.020
alpha amino acid metabolic processGO:1901605590.020
leukocyte migrationGO:00509001240.020
regulation of cell cycleGO:00517262810.020
response to epidermal growth factorGO:007084940.020
hormone secretionGO:00468791280.020
positive regulation of cell motilityGO:20001471160.020
nucleoside phosphate biosynthetic processGO:1901293790.020
positive regulation of intracellular transportGO:0032388700.020
osteoclast differentiationGO:0030316620.020
regulation of map kinase activityGO:00434051200.020
neuron projection guidanceGO:00974851410.020
septum primum developmentGO:000328440.019
ameboidal type cell migrationGO:00016671280.019
phosphatidylinositol metabolic processGO:0046488450.019
digestive system developmentGO:00551232000.019
blood circulationGO:00080151950.019
single organism nuclear importGO:1902593950.019
regulation of vitamin metabolic processGO:003065630.019
small molecule biosynthetic processGO:00442831320.019
negative regulation of phosphorylationGO:00423261660.019
multicellular organismal signalingGO:0035637910.019
regulation of hormone secretionGO:0046883880.019
cellular response to acid chemicalGO:0071229680.019
iron ion homeostasisGO:0055072360.019
compound eye developmentGO:004874910.019
neurotransmitter secretionGO:0007269620.019
cellular polysaccharide metabolic processGO:0044264380.019
endocytosisGO:00068971680.019
positive regulation of programmed cell deathGO:00430682180.019
primary neural tube formationGO:0014020950.019
regulation of urine volumeGO:003580960.019
spermatid developmentGO:00072861080.019
regulation of response to woundingGO:19030341890.019
midgut developmentGO:000749440.018
negative regulation of immune system processGO:00026832090.018
glucose metabolic processGO:0006006920.018
cellular response to hormone stimulusGO:00328701500.018
mesenchymal cell differentiationGO:00487621070.018
sympathetic neuron projection extensionGO:009749040.018
retrograde transport endosome to golgiGO:004214720.018
regulation of protein serine threonine kinase activityGO:00719001570.018
glycoprotein biosynthetic processGO:0009101890.018
gonadotrophin releasing hormone neuronal migration to the hypothalamusGO:002182830.018
embryonic appendage morphogenesisGO:00351131260.018
positive regulation of transferase activityGO:00513471670.018
calcium ion transportGO:00068161590.018
neuron migrationGO:00017641220.018
peptidyl tyrosine phosphorylationGO:00181081430.018
phospholipid metabolic processGO:0006644870.018
bone mineralizationGO:0030282540.018
cardiac septum developmentGO:0003279590.018
protein kinase b signalingGO:0043491740.018
potassium ion homeostasisGO:005507540.018
sulfur compound metabolic processGO:00067901000.018
organic acid biosynthetic processGO:0016053860.018
hair follicle developmentGO:0001942850.018
mesonephros developmentGO:0001823970.018
male sex differentiationGO:00466611090.018
negative regulation of apoptotic signaling pathwayGO:20012341040.018
regulation of defense responseGO:00313472330.017
negative regulation of secretionGO:0051048610.017
heterocycle catabolic processGO:00467002800.017
sequestering of calcium ionGO:0051208180.017
inorganic cation transmembrane transportGO:00986622070.017
negative regulation of hydrolase activityGO:0051346710.017
sensory perception of light stimulusGO:0050953540.017
response to oxidative stressGO:00069791230.017
neural precursor cell proliferationGO:00613511210.017
muscle system processGO:00030121410.017
amino acid transportGO:0006865610.017
fatty acid metabolic processGO:00066311210.017
lipid homeostasisGO:0055088630.017
regulation of organ morphogenesisGO:20000271440.017
response to molecule of bacterial originGO:00022371430.017
germ cell developmentGO:00072811850.017
positive regulation of apoptotic processGO:00430652170.017
sympathetic nervous system developmentGO:0048485220.017
regulation of angiogenesisGO:0045765810.017
regulation of peptidyl tyrosine phosphorylationGO:0050730930.017
glycosyl compound metabolic processGO:19016572460.017
muscle fiber developmentGO:0048747760.017
dna metabolic processGO:00062593030.017
regulation of blood pressureGO:0008217930.017
spermatid differentiationGO:00485151150.017
cofactor metabolic processGO:0051186800.017
retinal blood vessel morphogenesisGO:006130430.016
establishment of organelle localizationGO:00516561220.016
cellular response to oxidative stressGO:0034599760.016
regulation of osteoblast differentiationGO:0045667670.016
detection of external stimulusGO:0009581610.016
peptide secretionGO:00027901140.016
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574330.016
positive regulation of cytokine productionGO:00018191740.016
regulation of neuron differentiationGO:00456642810.016
cellular response to epidermal growth factor stimulusGO:007136440.016
positive regulation of smooth muscle cell migrationGO:001491140.016
sodium ion transmembrane transportGO:0035725490.016
t cell differentiation in thymusGO:0033077770.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
ribonucleoside triphosphate metabolic processGO:00091992200.016
reactive oxygen species metabolic processGO:0072593840.016
rhodopsin mediated signaling pathwayGO:001605640.016
methylationGO:00322591340.016
steroid metabolic processGO:00082021190.016
visual perceptionGO:0007601520.016
microtubule based processGO:00070172360.016
renal sodium excretionGO:003581230.016
negative regulation of ossificationGO:0030279490.016
polysaccharide metabolic processGO:0005976390.016
regulation of leukocyte differentiationGO:19021051590.016
positive regulation of neuron differentiationGO:00456661410.016
histone modificationGO:00165701590.016
response to peptideGO:19016521360.016
neurotransmitter transportGO:0006836760.015
cardiocyte differentiationGO:0035051870.015
face developmentGO:0060324380.015
peptide hormone secretionGO:00300721090.015
negative regulation of nervous system developmentGO:00519611560.015
rap protein signal transductionGO:003248630.015
one carbon metabolic processGO:000673010.015
coenzyme metabolic processGO:0006732520.015
gliogenesisGO:00420631410.015
regulation of nucleotide biosynthetic processGO:0030808340.015
facioacoustic ganglion developmentGO:190337530.015
detection of stimulusGO:0051606840.015
blastocyst developmentGO:0001824800.015
cell cell junction organizationGO:0045216720.015
cerebral cortex tangential migration using cell axon interactionsGO:002182430.015
adult behaviorGO:00305341350.015

Alpl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.052
disease of anatomical entityDOID:700.052
disease of metabolismDOID:001466700.029
inherited metabolic disorderDOID:65500.029
sensory system diseaseDOID:005015500.019
muscle tissue diseaseDOID:6600.016
muscular diseaseDOID:008000000.016
musculoskeletal system diseaseDOID:1700.016