IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Atp6v0c

ATPase, H+ transporting, lysosomal V0 subunit C

(Aliases: Atp6l,Atp6c,Atpl-rs1,Vma3,Atpl,Atp6c2,PL16,VATL)

Entrez: 11984
Ensembl: ENSMUSG00000024121
UniProtKB: P63082
UniProtKB: A3KML5

Process Predictions
Disease Predictions

Atp6v0c biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
transmembrane transport	GO:0055085	412	0.352	Zebrafish
hydrogen ion transmembrane transport	GO:1902600	25	0.329
inorganic cation transmembrane transport	GO:0098662	207	0.198	Zebrafish
ion transmembrane transport	GO:0034220	361	0.181	Zebrafish
cilium morphogenesis	GO:0060271	102	0.155
endocytosis	GO:0006897	168	0.103	Worm
inorganic ion transmembrane transport	GO:0098660	234	0.095	Zebrafish
purine ribonucleotide metabolic process	GO:0009150	290	0.095
nucleoside monophosphate metabolic process	GO:0009123	85	0.092
ribonucleotide metabolic process	GO:0009259	291	0.090
nucleobase containing small molecule metabolic process	GO:0055086	352	0.090
l ascorbic acid metabolic process	GO:0019852	4	0.088
apoptotic signaling pathway	GO:0097190	306	0.087
purine containing compound catabolic process	GO:0072523	213	0.087
positive regulation of necrotic cell death	GO:0010940	1	0.086	Worm
organonitrogen compound catabolic process	GO:1901565	264	0.080
purine containing compound metabolic process	GO:0072521	311	0.080
pigmentation	GO:0043473	71	0.078
organelle assembly	GO:0070925	177	0.078
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.075
cation transmembrane transport	GO:0098655	266	0.074	Zebrafish
organophosphate catabolic process	GO:0046434	232	0.074
intracellular protein transport	GO:0006886	204	0.074
organelle localization	GO:0051640	179	0.071
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.071
proton transport	GO:0015992	35	0.071
heterocycle catabolic process	GO:0046700	280	0.067
aromatic compound catabolic process	GO:0019439	286	0.065
cation transport	GO:0006812	399	0.061	Zebrafish
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.060
cellular amide metabolic process	GO:0043603	58	0.060
metal ion homeostasis	GO:0055065	189	0.059
ribonucleoside metabolic process	GO:0009119	245	0.058
retina development in camera type eye	GO:0060041	119	0.056	Zebrafish
receptor mediated endocytosis	GO:0006898	51	0.054	Worm
ribonucleoside monophosphate catabolic process	GO:0009158	57	0.053
regulation of secretion	GO:0051046	274	0.053
purine ribonucleoside catabolic process	GO:0046130	205	0.052
purine ribonucleotide catabolic process	GO:0009154	208	0.052
regulation of vesicle mediated transport	GO:0060627	139	0.051
atp metabolic process	GO:0046034	75	0.051
camera type eye development	GO:0043010	266	0.050	Zebrafish
cellular homeostasis	GO:0019725	240	0.050
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.049
nucleoside monophosphate catabolic process	GO:0009125	59	0.049
myeloid cell differentiation	GO:0030099	233	0.048
regulation of leukocyte differentiation	GO:1902105	159	0.046
nucleoside metabolic process	GO:0009116	246	0.046
regulation of secretion by cell	GO:1903530	249	0.046
rho protein signal transduction	GO:0007266	32	0.045
nucleoside phosphate metabolic process	GO:0006753	338	0.044
mapk cascade	GO:0000165	281	0.044
hydrogen transport	GO:0006818	35	0.044
organic cyclic compound catabolic process	GO:1901361	295	0.044
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.043
regulation of exocytosis	GO:0017157	61	0.043
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.043
cation homeostasis	GO:0055080	212	0.043
innate immune response	GO:0045087	157	0.042
kidney development	GO:0001822	213	0.042
molting cycle	GO:0042303	90	0.041	Worm
positive regulation of mapk cascade	GO:0043410	170	0.041
response to organonitrogen compound	GO:0010243	246	0.039
monovalent inorganic cation homeostasis	GO:0055067	33	0.038
hexose catabolic process	GO:0019320	3	0.038
melanosome organization	GO:0032438	8	0.037
renal system development	GO:0072001	225	0.037
glycosyl compound metabolic process	GO:1901657	246	0.037
purine nucleoside catabolic process	GO:0006152	205	0.036
negative regulation of protein metabolic process	GO:0051248	282	0.035
ribose phosphate metabolic process	GO:0019693	291	0.035
urogenital system development	GO:0001655	261	0.035
regulation of cellular amino acid metabolic process	GO:0006521	5	0.034
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.034
granzyme mediated apoptotic signaling pathway	GO:0008626	1	0.034
nucleotide metabolic process	GO:0009117	332	0.034
nucleoside triphosphate catabolic process	GO:0009143	205	0.033
nucleoside phosphate catabolic process	GO:1901292	222	0.033
response to copper ion	GO:0046688	3	0.033
bone remodeling	GO:0046849	53	0.033
regulation of intracellular transport	GO:0032386	159	0.033
embryonic organ morphogenesis	GO:0048562	276	0.032
regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway	GO:1902235	11	0.031
cellular chemical homeostasis	GO:0055082	215	0.031
maintenance of location	GO:0051235	89	0.031
ribonucleotide catabolic process	GO:0009261	208	0.031
positive regulation of cellular amine metabolic process	GO:0033240	5	0.031
regulation of protein transport	GO:0051223	163	0.031
cellular amino acid metabolic process	GO:0006520	103	0.030
neuronal action potential	GO:0019228	54	0.030
heart morphogenesis	GO:0003007	178	0.030
exocytosis	GO:0006887	121	0.030
water soluble vitamin biosynthetic process	GO:0042364	3	0.030
ras protein signal transduction	GO:0007265	77	0.030
kidney epithelium development	GO:0072073	121	0.030
regulation of mapk cascade	GO:0043408	248	0.029
regulation of establishment of protein localization	GO:0070201	181	0.029
atp catabolic process	GO:0006200	55	0.029
skin development	GO:0043588	220	0.029
regulation of transferase activity	GO:0051338	263	0.028
purine nucleotide metabolic process	GO:0006163	302	0.028
blood circulation	GO:0008015	195	0.028
sensory system development	GO:0048880	3	0.028
posttranscriptional regulation of gene expression	GO:0010608	155	0.028	Worm
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.027
natural killer cell activation involved in immune response	GO:0002323	10	0.027
small gtpase mediated signal transduction	GO:0007264	97	0.027
response to organic cyclic compound	GO:0014070	198	0.027
regulated secretory pathway	GO:0045055	32	0.027
epithelial tube morphogenesis	GO:0060562	303	0.026
myeloid leukocyte differentiation	GO:0002573	119	0.026
glycosyl compound catabolic process	GO:1901658	206	0.025
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.025
hormone metabolic process	GO:0042445	86	0.025
negative regulation of cellular protein metabolic process	GO:0032269	247	0.025
central nervous system neuron differentiation	GO:0021953	162	0.025
cellular nitrogen compound catabolic process	GO:0044270	280	0.025
tissue remodeling	GO:0048771	102	0.025
positive regulation of osteoclast differentiation	GO:0045672	15	0.025
dna metabolic process	GO:0006259	303	0.025
nucleoside triphosphate metabolic process	GO:0009141	230	0.025
osteoclast differentiation	GO:0030316	62	0.024
protein localization to organelle	GO:0033365	185	0.024
purine ribonucleoside metabolic process	GO:0046128	241	0.024
second messenger mediated signaling	GO:0019932	73	0.024
carbohydrate derivative catabolic process	GO:1901136	231	0.023
regulation of neuron apoptotic process	GO:0043523	122	0.023
multicellular organismal homeostasis	GO:0048871	164	0.023
ossification	GO:0001503	216	0.023
carbohydrate catabolic process	GO:0016052	32	0.023
natural killer cell degranulation	GO:0043320	3	0.022
regulation of cellular response to stress	GO:0080135	159	0.022
cellular ketone metabolic process	GO:0042180	84	0.022
cellular amine metabolic process	GO:0044106	44	0.022
developmental maturation	GO:0021700	193	0.022
immune effector process	GO:0002252	321	0.021
purine nucleoside monophosphate catabolic process	GO:0009128	58	0.021
positive regulation of cell development	GO:0010720	237	0.021
pigment granule organization	GO:0048753	9	0.021
l ascorbic acid biosynthetic process	GO:0019853	3	0.021
anatomical structure homeostasis	GO:0060249	145	0.021
tissue homeostasis	GO:0001894	115	0.021
regulation of cell activation	GO:0050865	289	0.020
cellular component assembly involved in morphogenesis	GO:0010927	139	0.020
regulation of protein localization	GO:0032880	231	0.020
cellular pigmentation	GO:0033059	20	0.020
anion transport	GO:0006820	177	0.020
regulation of blood pressure	GO:0008217	93	0.020
negative regulation of neuron death	GO:1901215	98	0.020
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.020
calcium ion homeostasis	GO:0055074	127	0.020
epithelial cell development	GO:0002064	159	0.019
cell maturation	GO:0048469	127	0.019
response to amino acid	GO:0043200	37	0.019
cell type specific apoptotic process	GO:0097285	268	0.019
amine metabolic process	GO:0009308	45	0.019
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.019
leukocyte activation involved in immune response	GO:0002366	126	0.019
cell adhesion	GO:0007155	329	0.019
vesicle organization	GO:0016050	60	0.019
regulation of apoptotic signaling pathway	GO:2001233	197	0.019
purine nucleotide catabolic process	GO:0006195	211	0.019
protein localization to plasma membrane	GO:0072659	57	0.019
golgi to endosome transport	GO:0006895	3	0.018
interspecies interaction between organisms	GO:0044419	83	0.018
ribonucleoside catabolic process	GO:0042454	206	0.018
hematopoietic progenitor cell differentiation	GO:0002244	143	0.018
cytoplasmic transport	GO:0016482	234	0.018
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.018
stem cell differentiation	GO:0048863	268	0.018
early endosome to late endosome transport	GO:0045022	2	0.017
ketone catabolic process	GO:0042182	3	0.017
lateral line system development	GO:0048925	1	0.017
positive regulation of secretion	GO:0051047	130	0.017
carboxylic acid biosynthetic process	GO:0046394	86	0.017
erk1 and erk2 cascade	GO:0070371	77	0.017
regulation of angiotensin metabolic process	GO:0060177	4	0.017
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.017
peptide metabolic process	GO:0006518	46	0.016
regulation of osteoclast differentiation	GO:0045670	36	0.016
positive regulation of erk1 and erk2 cascade	GO:0070374	47	0.016
positive regulation of transferase activity	GO:0051347	167	0.016
regulation of ph	GO:0006885	26	0.016
membrane organization	GO:0061024	245	0.016
circulatory system process	GO:0003013	197	0.016
nucleotide catabolic process	GO:0009166	217	0.016
positive regulation of exocytosis	GO:0045921	20	0.016
cellular response to abiotic stimulus	GO:0071214	56	0.016
meiotic cell cycle	GO:0051321	122	0.016
regulation of multi organism process	GO:0043900	111	0.016
divalent metal ion transport	GO:0070838	172	0.016	Zebrafish
leukocyte differentiation	GO:0002521	342	0.016
regulation of erk1 and erk2 cascade	GO:0070372	71	0.016
regulation of hormone levels	GO:0010817	211	0.016
development of primary sexual characteristics	GO:0045137	143	0.016	Worm
regulation of systemic arterial blood pressure	GO:0003073	61	0.015
epidermis development	GO:0008544	187	0.015
extrinsic apoptotic signaling pathway	GO:0097191	126	0.015
spermatogenesis	GO:0007283	284	0.015
sensory perception	GO:0007600	245	0.015
regulation of cellular ketone metabolic process	GO:0010565	66	0.015
cellular response to arsenic containing substance	GO:0071243	4	0.015
gland development	GO:0048732	330	0.015
positive regulation of bone resorption	GO:0045780	13	0.015
regulation of cellular amine metabolic process	GO:0033238	20	0.015
male sex differentiation	GO:0046661	109	0.015
ear development	GO:0043583	200	0.015
establishment of organelle localization	GO:0051656	122	0.015
purine ribonucleoside monophosphate catabolic process	GO:0009169	57	0.014
response to inorganic substance	GO:0010035	96	0.014
negative regulation of intracellular signal transduction	GO:1902532	167	0.014
regulation of proteolysis	GO:0030162	164	0.014
cellular response to organonitrogen compound	GO:0071417	145	0.014
nuclear import	GO:0051170	95	0.014
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.014
cellular ion homeostasis	GO:0006873	165	0.014
regulation of lymphocyte activation	GO:0051249	240	0.014
positive regulation of protein modification process	GO:0031401	299	0.014
sensory organ morphogenesis	GO:0090596	242	0.014	Zebrafish
striated muscle tissue development	GO:0014706	293	0.014
retinal pigment epithelium development	GO:0003406	6	0.014
vacuole organization	GO:0007033	38	0.014	Zebrafish
calcium ion transport	GO:0006816	159	0.014	Zebrafish
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.014
wound healing	GO:0042060	157	0.014
response to peptide	GO:1901652	136	0.014
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	34	0.014
single organism nuclear import	GO:1902593	95	0.014
mesonephros development	GO:0001823	97	0.014
monosaccharide biosynthetic process	GO:0046364	44	0.013
response to transition metal nanoparticle	GO:1990267	11	0.013
regulation of anatomical structure size	GO:0090066	178	0.013
purine nucleoside metabolic process	GO:0042278	241	0.013
macromolecule catabolic process	GO:0009057	281	0.013
cellular metal ion homeostasis	GO:0006875	151	0.013
positive regulation of secretion by cell	GO:1903532	114	0.013
male gonad development	GO:0008584	88	0.013
g protein coupled receptor signaling pathway	GO:0007186	243	0.013
cellular transition metal ion homeostasis	GO:0046916	32	0.013
synapse organization	GO:0050808	125	0.013
substantia nigra development	GO:0021762	2	0.013
regulation of intracellular protein transport	GO:0033157	82	0.013
cellular response to hormone stimulus	GO:0032870	150	0.013
cell fate commitment	GO:0045165	210	0.013
cell activation involved in immune response	GO:0002263	126	0.013
positive regulation of leukocyte differentiation	GO:1902107	86	0.013
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.013
nucleocytoplasmic transport	GO:0006913	139	0.013
negative regulation of cellular amine metabolic process	GO:0033239	1	0.013
negative regulation of multi organism process	GO:0043901	68	0.013
positive regulation of organelle organization	GO:0010638	128	0.013
regulation of myeloid cell differentiation	GO:0045637	96	0.012
regulation of defense response	GO:0031347	233	0.012
cellular protein complex assembly	GO:0043623	116	0.012
regulation of cellular component biogenesis	GO:0044087	181	0.012
localization within membrane	GO:0051668	4	0.012
regulation of regulated secretory pathway	GO:1903305	20	0.012
progesterone metabolic process	GO:0042448	4	0.012
negative regulation of molecular function	GO:0044092	258	0.012
autophagy	GO:0006914	45	0.012
regulation of lamellipodium assembly	GO:0010591	3	0.012
response to peptide hormone	GO:0043434	127	0.012
neuron apoptotic process	GO:0051402	142	0.012
protein processing	GO:0016485	163	0.012
actin cytoskeleton organization	GO:0030036	220	0.012
skeletal muscle organ development	GO:0060538	163	0.012
organonitrogen compound biosynthetic process	GO:1901566	192	0.012
regulation of ion transport	GO:0043269	215	0.012	Zebrafish
necrotic cell death	GO:0070265	30	0.012	Worm
male gamete generation	GO:0048232	285	0.012
developmental growth involved in morphogenesis	GO:0060560	138	0.012
cellular response to dna damage stimulus	GO:0006974	207	0.012
regulation of cellular catabolic process	GO:0031329	242	0.012
establishment of vesicle localization	GO:0051650	81	0.012
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.012
protein localization to membrane	GO:0072657	108	0.011
regulation of cell size	GO:0008361	72	0.011
regulation of ossification	GO:0030278	112	0.011
negative regulation of neuron apoptotic process	GO:0043524	92	0.011
microtubule cytoskeleton organization	GO:0000226	157	0.011
sequestering of metal ion	GO:0051238	19	0.011
organism emergence from protective structure	GO:0071684	4	0.011
regulation of homeostatic process	GO:0032844	182	0.011
regulation of arp2 3 complex mediated actin nucleation	GO:0034315	1	0.011
regulation of membrane potential	GO:0042391	192	0.011
regulation of kinase activity	GO:0043549	249	0.011
regulation of cytoplasmic transport	GO:1903649	112	0.011
reactive oxygen species metabolic process	GO:0072593	84	0.011
regulation of cell cycle	GO:0051726	281	0.011
fat cell differentiation	GO:0045444	160	0.011
divalent inorganic cation transport	GO:0072511	178	0.011	Zebrafish
positive regulation of cellular component biogenesis	GO:0044089	94	0.011
action potential	GO:0001508	78	0.011
regulation of neuron differentiation	GO:0045664	281	0.011
t cell differentiation	GO:0030217	174	0.011
myosin filament organization	GO:0031033	3	0.011
positive regulation of ossification	GO:0045778	47	0.011
protein catabolic process	GO:0030163	221	0.011
divalent inorganic cation homeostasis	GO:0072507	138	0.011
regulation of metal ion transport	GO:0010959	106	0.011
sequestering of calcium ion	GO:0051208	18	0.011
establishment of protein localization to organelle	GO:0072594	118	0.011
transition metal ion homeostasis	GO:0055076	54	0.011
hair cell differentiation	GO:0035315	40	0.011
peptide transport	GO:0015833	133	0.010
lipid localization	GO:0010876	126	0.010
protein import into nucleus	GO:0006606	95	0.010
cellular lipid metabolic process	GO:0044255	323	0.010
intrinsic apoptotic signaling pathway	GO:0097193	132	0.010
placenta development	GO:0001890	140	0.010
regulation of cellular component size	GO:0032535	121	0.010
regulation of binding	GO:0051098	111	0.010
leukocyte mediated immunity	GO:0002443	174	0.010
peptidyl amino acid modification	GO:0018193	336	0.010
snare complex disassembly	GO:0035494	2	0.010
regulation of rho protein signal transduction	GO:0035023	71	0.010
carbohydrate biosynthetic process	GO:0016051	74	0.010
response to acid chemical	GO:0001101	111	0.010
negative regulation of protein modification process	GO:0031400	163	0.010
myosin filament assembly	GO:0031034	2	0.010
positive regulation of defense response	GO:0031349	124	0.010
response to mineralocorticoid	GO:0051385	1	0.010

Atp6v0c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.037
inherited metabolic disorder	DOID:655	0.015
central nervous system disease	DOID:331	0.015
nervous system disease	DOID:863	0.015
disease of anatomical entity	DOID:7	0.015
brain disease	DOID:936	0.015
sphingolipidosis	DOID:1927	0.013
lysosomal storage disease	DOID:3211	0.013
lipid storage disease	DOID:9455	0.013
immune system disease	DOID:2914	0.010

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