Mus musculus

375 known processes

Axin1

axin 1

(Aliases: Kb,Axin,fused,Fu,kinky,knobbly,Ki,AI316800,MGC132911)

Axin1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pigment accumulationGO:004347611.000
proteolysis involved in cellular protein catabolic processGO:00516031471.000
positive regulation of cellular protein catabolic processGO:1903364340.999
negative regulation of peptidyl serine phosphorylationGO:0033137100.999
positive regulation of cell proliferation involved in heart valve morphogenesisGO:000325110.997
cellular protein catabolic processGO:00442571550.997
modification dependent macromolecule catabolic processGO:00436321330.996
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.995
ubiquitin dependent protein catabolic processGO:00065111290.994
regulation of cellular protein catabolic processGO:1903362610.994
negative regulation of cell growth involved in cardiac muscle cell developmentGO:006105220.994
protein catabolic processGO:00301632210.992
protein modification by small protein conjugation or removalGO:00706472070.992
metanephric mesenchyme morphogenesisGO:007213340.991
positive regulation of proteolysisGO:0045862850.991
peptidyl threonine phosphorylationGO:0018107310.990
negative regulation of phosphorylationGO:00423261660.989
modification dependent protein catabolic processGO:00199411330.989
wnt signaling pathwayGO:00160551880.988
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.987
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.987
regulation of protein serine threonine kinase activityGO:00719001570.984
cell proliferation involved in heart valve morphogenesisGO:000324910.983
regulation of mapk cascadeGO:00434082480.983
negative regulation of cellular amine metabolic processGO:003323910.982
nephrogenic mesenchyme morphogenesisGO:007213420.979
regulation of cellular amine metabolic processGO:0033238200.978
negative regulation of synapse assemblyGO:005196430.977
regulation of proteasomal protein catabolic processGO:0061136460.975
negative regulation of protein phosphorylationGO:00019331260.975
negative regulation of cellular amino acid metabolic processGO:004576300.973
negative regulation of osteoblast proliferationGO:003368940.973
cellular ketone metabolic processGO:0042180840.973
negative regulation of phosphate metabolic processGO:00459361840.972
cellular macromolecule catabolic processGO:00442652060.971
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayGO:190103060.969
macromolecule catabolic processGO:00090572810.969
osteoblast developmentGO:0002076170.967
negative regulation of phosphorus metabolic processGO:00105631840.966
regulation of jnk cascadeGO:0046328620.964
regulation of protein import into nucleusGO:0042306520.961
cellular amino acid metabolic processGO:00065201030.961
regulation of neuron differentiationGO:00456642810.961
regulation of jun kinase activityGO:0043506400.960
regulation of transferase activityGO:00513382630.957
establishment of tissue polarityGO:0007164280.956
digestive tract morphogenesisGO:00485461470.954
physiological cardiac muscle hypertrophyGO:000330130.953
positive regulation of protein serine threonine kinase activityGO:00719021060.953
nuclear transportGO:00511691390.952
negative regulation of cellular protein metabolic processGO:00322692470.951
regulation of cellular ketone metabolic processGO:0010565660.947
negative regulation of peptidyl threonine phosphorylationGO:001080160.946
kidney mesenchyme morphogenesisGO:007213140.945
peptidyl threonine modificationGO:0018210310.945
synaptic growth at neuromuscular junctionGO:005112460.944
mapk cascadeGO:00001652810.943
regulation of smad protein import into nucleusGO:006039030.941
establishment of protein localization to organelleGO:00725941180.941
protein targetingGO:00066051430.939
response to endoplasmic reticulum stressGO:0034976530.939
regulation of protein catabolic processGO:00421761080.939
regulation of bindingGO:00510981110.938
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.933
canonical wnt signaling pathway involved in heart developmentGO:006131630.932
cytoplasmic transportGO:00164822340.932
peptidyl amino acid modificationGO:00181933360.931
digestive tract developmentGO:00485651900.930
regulation of cellular amino acid metabolic processGO:000652150.928
jnk cascadeGO:0007254720.927
endothelial cell activationGO:004211810.926
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.925
regulation of protein kinase activityGO:00458592320.925
positive regulation of protein modification processGO:00314012990.921
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.920
cardiac chamber morphogenesisGO:0003206930.915
hypermethylation of cpg islandGO:004402730.914
positive regulation of nucleocytoplasmic transportGO:0046824300.912
digestive system developmentGO:00551232000.910
amine metabolic processGO:0009308450.907
positive regulation of stem cell differentiationGO:2000738230.906
cellular amine metabolic processGO:0044106440.905
regulation of cell growth involved in cardiac muscle cell developmentGO:006105030.902
canonical wnt signaling pathway involved in regulation of cell proliferationGO:004434030.901
canonical wnt signaling pathwayGO:00600701300.897
cell proliferation involved in heart valve developmentGO:200079320.897
negative regulation of protein modification processGO:00314001630.893
positive regulation of programmed cell deathGO:00430682180.892
regulation of cellular catabolic processGO:00313292420.891
protein localization to nucleusGO:00345041210.889
non canonical wnt signaling pathwayGO:0035567330.887
regulation of neuron projection developmentGO:00109751690.883
positive regulation of jun kinase activityGO:0043507300.881
positive regulation of protein phosphorylationGO:00019342420.878
epithelial to mesenchymal transition involved in endocardial cushion formationGO:0003198100.878
stress activated protein kinase signaling cascadeGO:0031098810.876
developmental growth involved in morphogenesisGO:00605601380.875
regulation of planar cell polarity pathway involved in outflow tract morphogenesisGO:200016310.874
cardiac muscle tissue developmentGO:00487381300.871
response to transforming growth factor betaGO:0071559880.871
positive regulation of apoptotic signaling pathwayGO:2001235950.868
positive regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902110110.868
negative regulation of ossificationGO:0030279490.867
Mouse
regulation of peptidyl threonine phosphorylationGO:0010799120.865
positive regulation of mapk cascadeGO:00434101700.864
regulation of establishment of planar polarityGO:0090175280.862
negative regulation of nfat protein import into nucleusGO:005153430.857
cell growth involved in cardiac muscle cell developmentGO:006104930.855
protein import into nucleusGO:0006606950.852
nephrogenic mesenchyme developmentGO:007207630.851
negative regulation of protein metabolic processGO:00512482820.850
regulation of synaptic growth at neuromuscular junctionGO:000858240.848
heart morphogenesisGO:00030071780.846
Mouse
single organism nuclear importGO:1902593950.844
regulation of chromosome organizationGO:0033044830.841
Mouse
positive regulation of kinase activityGO:00336741550.840
activation of mapkk activityGO:0000186150.839
nucleocytoplasmic transportGO:00069131390.839
regulation of map kinase activityGO:00434051200.839
positive regulation of protein ubiquitinationGO:0031398270.836
intracellular protein transportGO:00068862040.835
wnt signaling pathway planar cell polarity pathwayGO:0060071270.831
regulation of nucleocytoplasmic transportGO:0046822730.831
positive regulation of cell deathGO:00109422240.829
negative regulation of transferase activityGO:0051348850.828
formation of radial glial scaffoldsGO:002194340.827
mesenchymal cell developmentGO:0014031930.827
negative regulation of cholesterol transportGO:003237540.826
regulation of cell proliferation involved in heart valve morphogenesisGO:000325010.826
cell adhesionGO:00071553290.823
proteasomal protein catabolic processGO:0010498980.822
negative regulation of pathway restricted smad protein phosphorylationGO:006039410.819
peptidyl tyrosine phosphorylationGO:00181081430.819
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152270.818
regulation of peptidyl serine phosphorylationGO:0033135390.818
negative regulation of kinase activityGO:0033673810.817
regionalizationGO:00030023370.808
negative regulation of molecular functionGO:00440922580.808
regulation of stress activated mapk cascadeGO:0032872690.808
ventricular septum developmentGO:0003281420.808
insulin secretionGO:0030073890.805
positive regulation of cellular catabolic processGO:00313311480.800
inositol phosphate mediated signalingGO:0048016130.798
regulation of calcineurin nfat signaling cascadeGO:007088450.795
morphogenesis of a polarized epitheliumGO:0001738370.794
regulation of muscle tissue developmentGO:1901861970.793
metencephalon developmentGO:0022037890.790
cellular response to growth factor stimulusGO:00713631970.790
establishment of planar polarityGO:0001736280.790
cardiac endothelial cell differentiationGO:000334840.789
negative regulation of cardiac muscle tissue developmentGO:005502680.789
regulation of non canonical wnt signaling pathwayGO:2000050120.781
negative regulation of cell proliferationGO:00082852960.780
Mouse
regulation of peptidyl tyrosine phosphorylationGO:0050730930.776
negative regulation of jun kinase activityGO:004350890.772
positive regulation of cytoplasmic transportGO:1903651400.768
transforming growth factor beta receptor signaling pathwayGO:0007179710.767
regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014810.764
negative regulation of planar cell polarity pathway involved in pericardium morphogenesisGO:200016610.764
mesenchyme developmentGO:00604851520.759
negative regulation of platelet derived growth factor receptor beta signaling pathwayGO:200058720.755
segmentationGO:0035282930.754
Zebrafish Mouse
axonogenesisGO:00074092740.754
Worm
regulation of protein transportGO:00512231630.752
regulation of intracellular transportGO:00323861590.750
regulation of mitochondrion organizationGO:0010821270.749
epidermis developmentGO:00085441870.748
establishment of planar polarity involved in neural tube closureGO:0090177150.747
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.746
regulation of protein targetingGO:1903533610.739
cardiocyte differentiationGO:0035051870.738
angiogenesisGO:00015252010.736
positive regulation of smad protein import into nucleusGO:006039120.734
small gtpase mediated signal transductionGO:0007264970.732
protein ubiquitinationGO:00165671710.730
hair follicle developmentGO:0001942850.730
regulation of proteolysisGO:00301621640.725
regulation of phospholipase a2 activityGO:003242930.721
regulation of heart contractionGO:0008016770.718
dna metabolic processGO:00062593030.717
myeloid cell homeostasisGO:00022621140.706
regulation of protein localization to nucleusGO:1900180600.706
neural tube formationGO:00018411080.703
embryonic epithelial tube formationGO:00018381300.702
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:200016210.698
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.697
hormone secretionGO:00468791280.693
negative regulation of planar cell polarity pathway involved in heart morphogenesisGO:200016010.693
cellular protein complex assemblyGO:00436231160.692
Human
stem cell differentiationGO:00488632680.689
Fly
ventricular septum morphogenesisGO:0060412270.689
regulation of actin cytoskeleton organizationGO:0032956840.684
regulation of cytoplasmic transportGO:19036491120.683
protein localization to organelleGO:00333651850.679
striated muscle tissue developmentGO:00147062930.674
regulation of organ morphogenesisGO:20000271440.670
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014910.670
peptide hormone secretionGO:00300721090.668
chemotaxisGO:00069352470.662
Worm
nuclear importGO:0051170950.662
regulation of sequence specific dna binding transcription factor activityGO:00510901060.660
branching morphogenesis of an epithelial tubeGO:00487541590.657
regulation of ossificationGO:00302781120.655
Mouse
regulation of cell morphogenesis involved in differentiationGO:00107691510.654
cardiac muscle tissue morphogenesisGO:0055008440.654
pigmentationGO:0043473710.653
regulation of intracellular protein transportGO:0033157820.652
positive regulation of protein catabolic processGO:0045732600.652
social behaviorGO:0035176210.649
skeletal system morphogenesisGO:00487052030.649
regulation of protein modification by small protein conjugation or removalGO:1903320570.648
epithelial tube formationGO:00721751300.646
regulation of protein stabilityGO:0031647520.645
skeletal system developmentGO:00015013560.641
regulation of protein localizationGO:00328802310.634
regulation of cellular response to stressGO:00801351590.631
protein polyubiquitinationGO:0000209330.629
engulfment of apoptotic cellGO:004365230.629
epithelial tube morphogenesisGO:00605623030.627
mammary gland duct morphogenesisGO:0060603380.626
inflammatory responseGO:00069542440.625
positive regulation of epithelial to mesenchymal transitionGO:0010718130.624
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.622
positive regulation of protein kinase activityGO:00458601440.622
brainstem developmentGO:000336030.618
physiological muscle hypertrophyGO:000329830.617
response to organic cyclic compoundGO:00140701980.616
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.616
microtubule based processGO:00070172360.609
neuron projection guidanceGO:00974851410.608
Worm
habituationGO:004695930.606
developmental cell growthGO:0048588840.605
negative regulation of protein serine threonine kinase activityGO:0071901490.602
regulation of cell growthGO:0001558910.598
regulation of protein bindingGO:0043393600.596
protein modification by small protein conjugationGO:00324461870.593
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.586
positive regulation of apoptotic processGO:00430652170.585
synapse organizationGO:00508081250.578
cardiac chamber developmentGO:00032051080.577
embryonic organ morphogenesisGO:00485622760.576
regulation of kinase activityGO:00435492490.576
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferationGO:006132420.574
ras protein signal transductionGO:0007265770.574
negative regulation of nervous system developmentGO:00519611560.571
cardiac ventricle developmentGO:0003231830.569
epithelial cell proliferationGO:00506731740.564
axon guidanceGO:00074111410.554
Worm
macromolecule methylationGO:00434141200.554
receptor mediated endocytosis of low density lipoprotein particle involved in cholesterol transportGO:009011810.554
mitochondrial outer membrane permeabilizationGO:0097345100.549
peptidyl serine modificationGO:0018209830.544
cardiac septum morphogenesisGO:0060411460.541
negative regulation of neuron differentiationGO:00456651010.539
positive regulation of cell developmentGO:00107202370.538
negative regulation of cellular component organizationGO:00511291940.538
regulation of osteoblast proliferationGO:0033688150.537
stem cell maintenanceGO:00198271300.536
Fly
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.535
mitochondrion organizationGO:00070051340.533
epithelial to mesenchymal transitionGO:0001837470.533
palate developmentGO:0060021760.533
ubiquitin dependent smad protein catabolic processGO:003057920.531
stem cell proliferationGO:00720891170.528
regulation of adrenergic receptor signaling pathwayGO:007187740.527
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesisGO:200016410.526
negative regulation of mapk cascadeGO:0043409650.526
neural tube developmentGO:00219151600.524
axis elongation involved in somitogenesisGO:009024540.524
positive regulation of intracellular protein transportGO:0090316420.522
camera type eye developmentGO:00430102660.520
myeloid leukocyte differentiationGO:00025731190.518
negative regulation of wnt signaling pathwayGO:0030178730.515
neural crest cell differentiationGO:0014033540.514
protein localization to microtubule cytoskeletonGO:007269880.514
positive regulation of mitochondrion organizationGO:0010822170.513
negative regulation of bmp signaling pathwayGO:0030514350.509
regulation of protein ubiquitinationGO:0031396520.506
positive regulation of protein localization to nucleusGO:1900182300.505
regulation of muscle system processGO:0090257800.500
calcineurin nfat signaling cascadeGO:003317380.496
regulation of cell cycle processGO:00105641600.493
Mouse
peptidyl serine phosphorylationGO:0018105740.492
cardiac septum developmentGO:0003279590.492
forebrain cell migrationGO:0021885580.489
wnt signaling pathway involved in somitogenesisGO:009024440.486
Zebrafish
muscle tissue morphogenesisGO:0060415530.483
negative regulation of wound healingGO:0061045140.483
regulation of epithelial cell proliferationGO:00506781410.482
anatomical structure homeostasisGO:00602491450.482
gastrulationGO:00073691160.481
endocardial cell differentiationGO:006095640.479
embryonic axis specificationGO:0000578300.479
protein export from nucleusGO:0006611200.478
telencephalon cell migrationGO:0022029550.477
negative regulation of growthGO:0045926990.475
muscle tissue developmentGO:00605373080.475
ossificationGO:00015032160.472
Mouse
positive regulation of cell adhesionGO:0045785800.471
stem cell developmentGO:00488642190.469
Fly
blood vessel morphogenesisGO:00485142850.468
regulation of wnt signaling pathway planar cell polarity pathwayGO:2000095100.467
circulatory system processGO:00030131970.465
primary neural tube formationGO:0014020950.462
positive regulation of wnt signaling pathwayGO:0030177450.462
bmp signaling pathwayGO:0030509930.458
covalent chromatin modificationGO:00165691630.457
hindbrain developmentGO:00309021280.455
regulation of bmp signaling pathwayGO:0030510600.455
positive regulation of map kinase activityGO:0043406840.454
regulation of stem cell differentiationGO:2000736500.453
mitochondrial outer membrane permeabilization involved in programmed cell deathGO:1902686110.449
hindbrain radial glia guided cell migrationGO:0021932120.443
mitotic cell cycle processGO:19030471590.441
Worm
negative regulation of planar cell polarity pathway involved in neural tube closureGO:200016810.440
cardiac ventricle morphogenesisGO:0003208500.439
hindbrain morphogenesisGO:0021575460.436
regulation of planar cell polarity pathway involved in heart morphogenesisGO:200015910.435
positive regulation of transferase activityGO:00513471670.435
embryonic skeletal system morphogenesisGO:0048704910.431
circadian rhythmGO:00076231140.430
regulation of ligase activityGO:0051340100.427
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.425
striated muscle contractionGO:0006941450.423
positive regulation of dna templated transcription elongationGO:003278620.420
regulation of fat cell differentiationGO:0045598810.419
forebrain developmentGO:00309003020.419
Zebrafish
erythrocyte differentiationGO:0030218880.418
regulation of establishment of protein localizationGO:00702011810.418
positive regulation of protein transportGO:0051222930.414
positive regulation of nervous system developmentGO:00519622210.414
regulation of epithelial to mesenchymal transitionGO:0010717220.414
regulation of blood circulationGO:1903522930.412
cardiac muscle contractionGO:0060048320.409
negative regulation of osteoblast differentiationGO:0045668300.409
Mouse
peptide secretionGO:00027901140.408
nuclear divisionGO:00002801580.408
positive regulation of ossificationGO:0045778470.406
signal transduction in absence of ligandGO:0038034550.403
positive regulation of transforming growth factor beta receptor signaling pathwayGO:0030511120.402
mesoderm developmentGO:00074981000.400
genetic imprintingGO:0071514270.399
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.399
morphogenesis of a branching structureGO:00017632030.398
regulation of defense responseGO:00313472330.397
negative regulation of sterol transportGO:003237240.396
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:200016110.394
apoptotic signaling pathwayGO:00971903060.394
myeloid cell differentiationGO:00300992330.393
negative regulation of fat cell differentiationGO:0045599360.393
regulation of apoptotic signaling pathwayGO:20012331970.392
lens development in camera type eyeGO:0002088620.390
regulation of cardiac muscle contractionGO:0055117210.385
bone developmentGO:00603481200.385
Mouse
regulation of nuclear divisionGO:0051783560.385
regulation of hormone levelsGO:00108172110.383
extrinsic apoptotic signaling pathwayGO:00971911260.379
renal system developmentGO:00720012250.378
positive regulation of protein import into nucleusGO:0042307260.375
positive regulation of stress activated mapk cascadeGO:0032874480.375
protein localization to microtubuleGO:003537230.375
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:200015110.374
planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:006135020.374
endoderm formationGO:0001706200.374
regulation of cell cycleGO:00517262810.373
Mouse
regulation of planar cell polarity pathway involved in neural tube closureGO:200016710.373
regulation of hydrolase activityGO:00513362460.372
regulation of presynaptic membrane organizationGO:190162930.368
positive regulation of cellular amino acid metabolic processGO:004576430.367
rho protein signal transductionGO:0007266320.367
response to growth factorGO:00708481980.366
ureteric bud morphogenesisGO:0060675620.366
somitogenesisGO:0001756690.361
Zebrafish Mouse
regulation of circadian rhythmGO:0042752580.361
cell junction assemblyGO:0034329520.361
regulation of mitotic cell cycleGO:00073461260.359
regulation of cardiac muscle tissue developmentGO:0055024310.355
tube formationGO:00351481400.354
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.354
mammary gland morphogenesisGO:0060443540.354
membrane organizationGO:00610242450.353
hexose metabolic processGO:0019318980.351
regulation of membrane permeabilityGO:0090559180.351
germline cell cycle switching mitotic to meiotic cell cycleGO:005172910.351
morphogenesis of embryonic epitheliumGO:00163311590.350
branching involved in ureteric bud morphogenesisGO:0001658560.349
cerebellum morphogenesisGO:0021587420.348
negative regulation of inflammatory responseGO:0050728610.346
regulation of platelet derived growth factor receptor beta signaling pathwayGO:200058620.341
regulation of cell divisionGO:0051302760.341
artery developmentGO:0060840530.340
presynaptic membrane assemblyGO:009710570.336
organ growthGO:00352651170.334
planar cell polarity pathway involved in pericardium morphogenesisGO:006135420.333
non canonical wnt signaling pathway involved in heart developmentGO:006134130.332
cellular response to organic cyclic compoundGO:0071407870.332
intracellular cholesterol transportGO:003236730.332
single organismal cell cell adhesionGO:00163371310.330
regulation of muscle contractionGO:0006937490.328
response to osmotic stressGO:0006970210.327
regulation of cell projection organizationGO:00313442060.327
positive regulation of intracellular transportGO:0032388700.326
positive regulation of cellular amine metabolic processGO:003324050.325
bone morphogenesisGO:0060349780.324
Mouse
heart contractionGO:0060047930.323
cell growthGO:00160491300.323
dna hypermethylationGO:004402630.322
response to organonitrogen compoundGO:00102432460.318
pathway restricted smad protein phosphorylationGO:0060389100.317
cellular homeostasisGO:00197252400.315
planar cell polarity pathway involved in heart morphogenesisGO:006134630.315
regulation of microtubule based processGO:0032886520.313
leukocyte differentiationGO:00025213420.313
positive regulation of bindingGO:0051099490.312
fat cell differentiationGO:00454441600.312
negative regulation of cardiac muscle cell differentiationGO:200072620.311
stress activated mapk cascadeGO:0051403800.308
adherens junction assemblyGO:0034333220.308
regulation of cell migrationGO:00303342190.307
gonad developmentGO:00084061410.307
Worm
neural tube closureGO:0001843900.305
negative regulation of cell cycleGO:00457861230.300
dephosphorylationGO:00163111290.300
regulation of metal ion transportGO:00109591060.298
gastrulation with mouth forming secondGO:0001702290.297
lung developmentGO:00303241640.296
regulation of cell adhesionGO:00301551540.296
endocardial cushion formationGO:0003272130.296
regulation of canonical wnt signaling pathwayGO:0060828820.295
regulation of heart morphogenesisGO:2000826220.293
endocytosisGO:00068971680.290
Fly
cellular response to dna damage stimulusGO:00069742070.288
regulation of cellular component biogenesisGO:00440871810.287
cardiac cell fate specificationGO:006091220.283
odontogenesisGO:0042476780.280
lipid localizationGO:00108761260.279
negative regulation of intracellular signal transductionGO:19025321670.279
kidney morphogenesisGO:0060993830.278
blood circulationGO:00080151950.278
positive regulation of chromosome segregationGO:005198440.275
positive regulation of mitotic sister chromatid separationGO:190197020.274
apoptotic mitochondrial changesGO:0008637480.273
urogenital system developmentGO:00016552610.271
regulation of protein maturationGO:1903317960.270
neural precursor cell proliferationGO:00613511210.270
midbrain developmentGO:0030901350.269
regulation of planar cell polarity pathway involved in pericardium morphogenesisGO:200016510.269
regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:200015010.269
wnt signaling pathway involved in forebrain neuroblast divisionGO:002187420.268
skeletal muscle acetylcholine gated channel clusteringGO:007134070.267
organic hydroxy compound transportGO:0015850930.267
platelet derived growth factor receptor signaling pathwayGO:0048008320.264
canonical wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart developmentGO:006131010.263
cardiac muscle tissue growthGO:0055017370.261
sebaceous gland developmentGO:004873370.258
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.258
dna repairGO:00062811070.257
planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:006134920.256
canonical wnt signaling pathway involved in neural crest cell differentiationGO:004433510.253
establishment of planar polarity of embryonic epitheliumGO:0042249160.253
regulation of mitochondrial membrane permeabilityGO:0046902170.252
negative regulation of bindingGO:0051100390.251
neural tube patterningGO:0021532430.250
microtubule cytoskeleton organizationGO:00002261570.247
negative regulation of platelet derived growth factor receptor signaling pathwayGO:001064270.246
organic hydroxy compound metabolic processGO:19016152030.246
protein autophosphorylationGO:0046777610.246
germ cell developmentGO:00072811850.244
Fly
smad protein signal transductionGO:0060395210.243
regulation of chromosome segregationGO:0051983210.242
Mouse
regulation of mitosisGO:0007088290.241
regulation of anatomical structure sizeGO:00900661780.239
cell proliferation involved in outflow tract morphogenesisGO:006132540.239
positive regulation of organelle organizationGO:00106381280.237
guanosine containing compound catabolic processGO:19010691440.237
methylationGO:00322591340.237
mitotic spindle organizationGO:0007052100.235
Worm
cell fate commitment involved in formation of primary germ layerGO:0060795260.232
tube closureGO:0060606910.231
cellular response to inorganic substanceGO:0071241370.230
negative regulation of intracellular protein transportGO:0090317270.230
negative regulation of cardiac chamber morphogenesisGO:190122020.229
pallium developmentGO:00215431200.228
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.227
outflow tract morphogenesisGO:0003151530.226
negative regulation of protein localization to nucleusGO:1900181230.226
cerebral cortex developmentGO:0021987860.225
negative regulation of cytoplasmic transportGO:1903650290.225
peptide transportGO:00158331330.222
endocardium developmentGO:0003157100.222
establishment of mitotic spindle localizationGO:0040001120.221
planar cell polarity pathway involved in outflow tract morphogenesisGO:006134720.221
regulation of cardiac cell fate specificationGO:200004310.220

Axin1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
gastrointestinal system cancerDOID:311900.788
Human
intestinal cancerDOID:1015500.788
cancerDOID:16200.788
Human
disease of cellular proliferationDOID:1456600.788
Human
organ system cancerDOID:005068600.788
Human
large intestine cancerDOID:567200.781