Mus musculus

290 known processes

Bak1

BCL2-antagonist/killer 1

(Aliases: N-Bak,N-BAK1,Bak)

Bak1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitochondrial fusionGO:000805391.000
positive regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902110110.994
Mouse
mitochondrial outer membrane permeabilization involved in programmed cell deathGO:1902686110.992
Mouse
positive regulation of mitochondrion organizationGO:0010822170.990
Worm
positive regulation of skeletal muscle fiber developmentGO:004874330.962
Mouse
regulation of pigment cell differentiationGO:005093270.955
Mouse
regulation of mammary gland involutionGO:190351940.917
Mouse
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.891
Mouse
regulation of mitochondrion organizationGO:0010821270.891
Worm
protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:000184440.844
Mouse
mitochondrion organizationGO:00070051340.819
apoptotic process involved in mammary gland involutionGO:006005740.810
Mouse
organelle fusionGO:0048284280.801
t cell homeostatic proliferationGO:000177740.791
Mouse
regulation of mitochondrial fissionGO:009014030.778
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126740.763
Mouse
membrane fusionGO:0061025380.756
positive regulation of melanocyte differentiationGO:004563650.752
Mouse
response to endoplasmic reticulum stressGO:0034976530.751
peptidyl amino acid modificationGO:00181933360.746
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126930.746
Mouse
necrotic cell deathGO:0070265300.746
Mouse
positive regulation of release of cytochrome c from mitochondriaGO:009020050.728
regulation of melanocyte differentiationGO:004563470.721
Mouse
cellular response to gamma radiationGO:007148040.688
Mouse
positive regulation of apoptotic process involved in morphogenesisGO:190233940.686
Mouse
positive regulation of neuron maturationGO:001404220.676
Mouse
cochlear nucleus developmentGO:002174740.667
Mouse
positive regulation of neuroepithelial cell differentiationGO:190291350.663
Mouse
cellular process regulating host cell cycle in response to virusGO:006015430.659
Mouse
positive regulation of cell maturationGO:190343140.625
Mouse
negative regulation of retinal cell programmed cell deathGO:004667120.571
Mouse
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome cGO:000863540.557
cd8 positive alpha beta t cell lineage commitmentGO:004337510.531
Mouse
viral processGO:0016032410.525
Mouse
mitochondrion morphogenesisGO:0070584130.504
Mouse
immune response activating signal transductionGO:00027571160.479
activation of immune responseGO:00022531380.447
response to ischemiaGO:0002931140.445
Mouse
response to uv bGO:001022450.440
Mouse
release of cytochrome c from mitochondriaGO:0001836230.425
positive regulation of b cell apoptotic processGO:000290440.423
Mouse
post embryonic eye morphogenesisGO:004805040.418
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.415
Mouse
regulation of membrane permeabilityGO:0090559180.407
Mouse
alpha beta t cell lineage commitmentGO:000236370.405
Mouse
negative regulation of peptidyl serine phosphorylationGO:0033137100.404
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.400
Mouse
negative regulation of endoplasmic reticulum calcium ion concentrationGO:003247130.398
response to osmotic stressGO:0006970210.388
Mouse
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathwayGO:190337630.378
Mouse
carbohydrate derivative biosynthetic processGO:19011371830.376
Mouse
regulation of release of cytochrome c from mitochondriaGO:0090199110.375
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathwayGO:190337830.370
Mouse
regulation of cell cycleGO:00517262810.360
regulation of cellular ketone metabolic processGO:0010565660.355
regulation of multi organism processGO:00439001110.347
Mouse
cellular lipid metabolic processGO:00442553230.347
Mouse
purine nucleoside metabolic processGO:00422782410.345
Worm
mitochondrial membrane organizationGO:0007006260.345
Mouse
posttranscriptional regulation of gene expressionGO:00106081550.344
Mouse
t cell activationGO:00421102890.338
Mouse
positive regulation of calcium ion transport into cytosolGO:001052490.334
programmed necrotic cell deathGO:0097300280.334
Mouse
calcium ion transportGO:00068161590.332
apoptotic process involved in embryonic digit morphogenesisGO:190226330.330
Mouse
positive regulation of cellular response to oxidative stressGO:190040960.328
Mouse
membrane organizationGO:00610242450.328
regulation of nitrogen utilizationGO:000680820.326
Mouse
response to amino acidGO:0043200370.317
Mouse
regulation of cell cycle processGO:00105641600.316
Mouse
interspecies interaction between organismsGO:0044419830.315
Mouse
leukocyte proliferationGO:00706611720.314
Mouse
regulation of cellular amine metabolic processGO:0033238200.311
regulation of cellular amino acid metabolic processGO:000652150.310
apoptotic signaling pathwayGO:00971903060.308
regulation of organ morphogenesisGO:20000271440.303
Mouse
striated muscle tissue developmentGO:00147062930.299
Mouse
negative regulation of calcium ion transport into cytosolGO:001052320.299
Mouse
positive regulation of mitochondrial membrane permeabilityGO:0035794120.298
Mouse
immune response regulating signaling pathwayGO:00027641250.293
cation transportGO:00068123990.292
cellular ketone metabolic processGO:0042180840.292
spermatid differentiationGO:00485151150.289
Mouse
sensory organ morphogenesisGO:00905962420.286
endoplasmic reticulum calcium ion homeostasisGO:0032469110.284
muscle tissue developmentGO:00605373080.277
Mouse
peptidyl threonine phosphorylationGO:0018107310.273
Mouse
peptidyl serine modificationGO:0018209830.272
heterocycle catabolic processGO:00467002800.272
Worm
cerebral cortex developmentGO:0021987860.270
Mouse
regulation of developmental pigmentationGO:0048070140.266
Mouse
male sex differentiationGO:00466611090.264
Mouse
t cell lineage commitmentGO:0002360130.263
Mouse
peptidyl threonine modificationGO:0018210310.262
Mouse
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.259
Mouse
amine metabolic processGO:0009308450.253
camera type eye developmentGO:00430102660.252
regulation of cellular response to stressGO:00801351590.250
Mouse
positive regulation of developmental pigmentationGO:004808760.249
Mouse
intrinsic apoptotic signaling pathwayGO:00971931320.249
cellular amino acid metabolic processGO:00065201030.249
b cell proliferationGO:0042100530.246
Mouse
skin developmentGO:00435882200.242
Mouse
ion transmembrane transportGO:00342203610.238
positive regulation of cellular amine metabolic processGO:003324050.236
t cell selectionGO:0045058340.235
Mouse
positive regulation of neuron apoptotic processGO:0043525250.234
Mouse
positive regulation of protein phosphorylationGO:00019342420.233
Mouse
stem cell differentiationGO:00488632680.231
Mouse
metencephalon developmentGO:0022037890.231
Mouse
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108140.230
Mouse
regulation of organelle organizationGO:00330432890.229
Worm
negative regulation of phosphate metabolic processGO:00459361840.229
ribonucleoside triphosphate catabolic processGO:00092031990.226
Worm
actin cytoskeleton organizationGO:00300362200.223
Mouse
lymphocyte proliferationGO:00466511640.220
Mouse
positive regulation of smooth muscle cell migrationGO:001491140.218
Mouse
apoptotic mitochondrial changesGO:0008637480.216
ribose phosphate metabolic processGO:00196932910.212
Worm
actin filament organizationGO:00070151130.212
Mouse
telencephalon developmentGO:00215371860.206
Mouse
positive regulation of protein oligomerizationGO:003246140.205
peptidyl serine phosphorylationGO:0018105740.205
mitochondrial fissionGO:0000266120.205
positive regulation of organelle organizationGO:00106381280.200
Worm
muscle cell differentiationGO:00426922610.199
Mouse
skeletal muscle fiber developmentGO:0048741580.198
Mouse
protein insertion into mitochondrial membraneGO:005120440.197
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092071990.196
Worm
negative regulation of protein metabolic processGO:00512482820.193
transmembrane transportGO:00550854120.190
immune response activating cell surface receptor signaling pathwayGO:0002429720.187
guanosine containing compound catabolic processGO:19010691440.186
Worm
multicellular organismal homeostasisGO:00488711640.185
Mouse
muscle cell developmentGO:00550011330.185
Mouse
cell type specific apoptotic processGO:00972852680.184
negative regulation of osteoblast proliferationGO:003368940.180
Mouse
mitochondrial transportGO:0006839360.179
Mouse
antigen receptor mediated signaling pathwayGO:0050851640.178
positive regulation of mammary gland involutionGO:190352140.176
Mouse
apoptotic process in bone marrowGO:007183910.172
Mouse
positive regulation of oxidative stress induced neuron deathGO:190322330.171
Mouse
digestive tract developmentGO:00485651900.170
Mouse
negative regulation of phosphorus metabolic processGO:00105631840.170
protein processingGO:00164851630.169
neuron apoptotic processGO:00514021420.169
Mouse
purine nucleotide catabolic processGO:00061952110.168
Worm
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.168
Mouse
b cell selectionGO:000233930.167
cell agingGO:0007569350.164
Mouse
regulation of protein stabilityGO:0031647520.161
Mouse
regulation of neuron apoptotic processGO:00435231220.160
Mouse
regulation of ion transportGO:00432692150.158
melanin metabolic processGO:0006582120.158
Mouse
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729620.158
Mouse
maintenance of locationGO:0051235890.157
cellular homeostasisGO:00197252400.157
response to radiationGO:00093141650.157
macromolecule catabolic processGO:00090572810.157
nucleotide metabolic processGO:00091173320.156
Worm
embryonic appendage morphogenesisGO:00351131260.151
Mouse
neuron deathGO:00709971540.150
Mouse
apoptotic process involved in patterning of blood vesselsGO:190226260.149
negative regulation of cellular protein metabolic processGO:00322692470.148
cellular response to dna damage stimulusGO:00069742070.148
glycosyl compound metabolic processGO:19016572460.147
Worm
muscle fiber developmentGO:0048747760.146
Mouse
positive regulation of protein modification processGO:00314012990.146
Mouse
myotube differentiationGO:00149021050.146
Mouse
regulation of mitochondrial membrane permeabilityGO:0046902170.144
Mouse
germ cell developmentGO:00072811850.143
Mouse
t cell proliferationGO:00420981200.142
Mouse
forebrain developmentGO:00309003020.141
Mouse
lymphocyte homeostasisGO:0002260640.141
symbiosis encompassing mutualism through parasitismGO:0044403830.140
Mouse
regulation of smooth muscle cell migrationGO:001491060.138
Mouse
response to light stimulusGO:00094161350.137
dna catabolic process endonucleolyticGO:0000737150.137
positive regulation of homeostatic processGO:0032846640.137
guanosine containing compound metabolic processGO:19010681440.133
Worm
b cell homeostasisGO:0001782340.132
t cell differentiation in thymusGO:0033077770.131
Mouse
positive regulation of response to oxidative stressGO:190288460.131
Mouse
appendage developmentGO:00487361660.130
pallium developmentGO:00215431200.130
Mouse
negative regulation of cell cycleGO:00457861230.129
Mouse
response to oxidative stressGO:00069791230.128
Mouse
response to organonitrogen compoundGO:00102432460.128
Mouse
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.128
Mouse
regulation of fibroblast proliferationGO:0048145340.127
Mouse
response to cycloheximideGO:004689810.126
Mouse
positive regulation of cellular component biogenesisGO:0044089940.126
positive regulation of apoptotic signaling pathwayGO:2001235950.125
Mouse
odontogenesis of dentin containing toothGO:0042475660.124
Mouse
release of sequestered calcium ion into cytosolGO:0051209420.124
Mouse
positive regulation of intracellular transportGO:0032388700.123
ear developmentGO:00435832000.122
Mouse
cell adhesionGO:00071553290.122
Mouse
sequestering of metal ionGO:0051238190.122
organelle fissionGO:00482851700.119
regulation of mitochondrial membrane permeability involved in programmed necrotic cell deathGO:190244520.118
Mouse
positive regulation of cell deathGO:00109422240.117
regulation of cell migrationGO:00303342190.117
Mouse
regulation of protein oligomerizationGO:003245940.116
appendage morphogenesisGO:00351071490.115
regulation of peptidyl serine phosphorylationGO:0033135390.115
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.114
Mouse
negative regulation of cell proliferationGO:00082852960.114
Mouse
negative regulation of mitotic cell cycle phase transitionGO:1901991450.113
Mouse
ossificationGO:00015032160.113
Mouse
regulation of cell activationGO:00508652890.112
cellular response to amino acid stimulusGO:0071230290.111
Mouse
sphingolipid metabolic processGO:0006665450.111
Mouse
aromatic compound catabolic processGO:00194392860.110
Worm
positive regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001241100.110
Mouse
morphogenesis of a branching structureGO:00017632030.109
t cell homeostasisGO:0043029350.109
Mouse
gtp metabolic processGO:00460391440.108
Worm
regulation of mitotic cell cycle phase transitionGO:1901990730.106
Mouse
regulation of cell adhesionGO:00301551540.106
Mouse
striated muscle cell developmentGO:00550021250.105
Mouse
epidermis developmentGO:00085441870.104
Mouse
multicellular organism growthGO:00352641610.104
Mouse
cellular response to glucose starvationGO:004214950.103
Mouse
secondary metabolic processGO:0019748180.103
Mouse
myeloid cell apoptotic processGO:0033028220.102
Mouse
glial cell apoptotic processGO:003434930.102
regulation of myotube differentiationGO:0010830620.102
Mouse
cellular macromolecule catabolic processGO:00442652060.100
homeostasis of number of cells within a tissueGO:0048873250.099
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092052200.099
Worm
regulation of cellular response to oxidative stressGO:1900407190.099
Mouse
positive regulation of gtpase activityGO:0043547850.099
Worm
glycolipid metabolic processGO:0006664250.098
Mouse
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.097
regulation of protein complex assemblyGO:0043254830.097
viral life cycleGO:0019058360.097
Mouse
regulation of neuron deathGO:19012141340.096
Mouse
modification by symbiont of host morphology or physiologyGO:004400340.095
microtubule based processGO:00070172360.095
cellular metal ion homeostasisGO:00068751510.095
male gamete generationGO:00482322850.094
Mouse
phenol containing compound metabolic processGO:0018958600.094
Mouse
male gonad developmentGO:0008584880.093
Mouse
negative regulation of growthGO:0045926990.093
Mouse
mesenchymal cell developmentGO:0014031930.093
Mouse
liposaccharide metabolic processGO:1903509270.093
Mouse
lymphocyte differentiationGO:00300982420.092
skeletal muscle organ developmentGO:00605381630.092
Mouse
ovarian follicle developmentGO:0001541400.092
Mouse
response to reactive oxygen speciesGO:0000302560.092
Mouse
covalent chromatin modificationGO:00165691630.091
tissue homeostasisGO:00018941150.091
Mouse
negative regulation of protein modification processGO:00314001630.091
alpha beta t cell activationGO:0046631910.090
Mouse
regulation of protein heterodimerization activityGO:004349720.090
g1 s transition of mitotic cell cycleGO:0000082570.090
Mouse
alpha beta t cell differentiationGO:0046632690.090
Mouse
purine nucleoside triphosphate metabolic processGO:00091442260.090
Worm
negative regulation of lymphocyte apoptotic processGO:0070229240.090
Mouse
nucleoside triphosphate catabolic processGO:00091432050.088
Worm
epithelial tube morphogenesisGO:00605623030.088
positive regulation of cellular amino acid metabolic processGO:004576430.087
pigment metabolic processGO:0042440320.087
Mouse
regulation of ion homeostasisGO:2000021640.087
cellular amine metabolic processGO:0044106440.086
pigmentationGO:0043473710.086
Mouse
regulation of proteolysisGO:00301621640.086
negative regulation of molecular functionGO:00440922580.086
viral genome replicationGO:0019079170.086
Mouse
negative regulation of neuron apoptotic processGO:0043524920.085
Mouse
negative regulation of phosphorylationGO:00423261660.085
pigment cell differentiationGO:0050931270.085
Mouse
purine ribonucleoside catabolic processGO:00461302050.085
Worm
regulation of apoptotic signaling pathwayGO:20012331970.085
Mouse
blood vessel morphogenesisGO:00485142850.084
calcium ion transport into cytosolGO:0060402480.084
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.084
Mouse
establishment of protein localization to organelleGO:00725941180.083
Mouse
leukocyte homeostasisGO:0001776790.083
thymus developmentGO:0048538410.083
Mouse
positive regulation of peptidase activityGO:0010952490.083
mitotic cell cycleGO:00002781950.082
Mouse
regulation of cell motilityGO:20001452360.082
Mouse
organophosphate catabolic processGO:00464342320.081
Worm
regulation of response to oxidative stressGO:1902882190.081
Mouse
positive regulation of cell motilityGO:20001471160.080
Mouse
regulation of g1 s transition of mitotic cell cycleGO:2000045350.080
Mouse
gtp catabolic processGO:00061841430.080
Worm
embryonic digit morphogenesisGO:0042733560.079
Mouse
gland developmentGO:00487323300.079
Mouse
cellular response to light stimulusGO:0071482190.079
cellular nitrogen compound catabolic processGO:00442702800.078
Worm
glycosyl compound catabolic processGO:19016582060.078
Worm
limb developmentGO:00601731660.078
extrinsic apoptotic signaling pathwayGO:00971911260.078
b cell differentiationGO:0030183780.077
regulation of cell substrate adhesionGO:0010810730.076
Mouse
mammary gland epithelial cell proliferationGO:0033598240.075
Mouse
purine ribonucleotide catabolic processGO:00091542080.075
Worm
ribonucleotide catabolic processGO:00092612080.074
Worm
pons developmentGO:0021548130.074
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.074
Mouse
cellular response to abiotic stimulusGO:0071214560.073
positive regulation of ion transportGO:0043270650.073
response to uvGO:0009411440.073
mammary gland morphogenesisGO:0060443540.072
Mouse
cellular response to virusGO:009858670.071
Mouse
response to hypoxiaGO:0001666580.071
Mouse
regulation of metal ion transportGO:00109591060.071
negative regulation of cellular amine metabolic processGO:003323910.071
positive regulation of purine nucleotide metabolic processGO:19005441140.071
Worm
spleen developmentGO:0048536390.071
Mouse
smooth muscle cell migrationGO:0014909100.070
Mouse
regulation of striated muscle cell differentiationGO:0051153810.070
Mouse
developmental programmed cell deathGO:0010623410.070
cell junction organizationGO:0034330770.070
Mouse
response to inorganic substanceGO:0010035960.069
Mouse
cellular response to organonitrogen compoundGO:00714171450.069
Mouse
regulation of cellular catabolic processGO:00313292420.069
Worm
positive regulation of calcium ion transportGO:0051928270.069
purine containing compound metabolic processGO:00725213110.068
Worm
negative regulation of cell developmentGO:00107211690.068
Mouse
chromatin organizationGO:00063252060.068
regulation of muscle tissue developmentGO:1901861970.068
Mouse
regulation of osteoblast proliferationGO:0033688150.068
Mouse
ribonucleoside catabolic processGO:00424542060.067
Worm
regulation of cellular component biogenesisGO:00440871810.067
neuroepithelial cell differentiationGO:0060563370.067
Mouse
regulation of protein homodimerization activityGO:004349640.067
odontogenesisGO:0042476780.066
Mouse
regulation of glycoprotein biosynthetic processGO:0010559120.066
Mouse
regulation of leukocyte proliferationGO:00706631210.066
mitotic cell cycle processGO:19030471590.065
Mouse
columnar cuboidal epithelial cell differentiationGO:0002065820.065
Mouse
retinal cell programmed cell deathGO:004666680.065
Mouse
immune effector processGO:00022523210.065
spermatogenesisGO:00072832840.064
Mouse
stem cell developmentGO:00488642190.064
Mouse
t cell apoptotic processGO:0070231390.064
myeloid cell homeostasisGO:00022621140.064
regulation of purine nucleotide metabolic processGO:19005421690.064
Worm
positive regulation of protein complex assemblyGO:0031334450.064
thymocyte apoptotic processGO:0070242190.064
reactive oxygen species metabolic processGO:0072593840.063
Mouse
hematopoietic progenitor cell differentiationGO:00022441430.063
Mouse
rhythmic processGO:00485111740.063
Mouse
female sex differentiationGO:0046660840.062
negative regulation of b cell apoptotic processGO:000290370.062
Mouse
nitrogen utilizationGO:001974020.062
Mouse
leukocyte differentiationGO:00025213420.062
purine ribonucleotide metabolic processGO:00091502900.062
Worm
positive regulation of tissue remodelingGO:0034105190.062
Mouse
retina development in camera type eyeGO:00600411190.062
Mouse
positive regulation of programmed cell deathGO:00430682180.062
cytosolic calcium ion transportGO:0060401480.062
protein homooligomerizationGO:0051260430.062
Mouse
apoptotic process involved in developmentGO:1902742280.061
cell substrate adhesionGO:00315891300.061
Mouse
purine ribonucleoside metabolic processGO:00461282410.061
Worm
cellular response to ionizing radiationGO:0071479110.061
Mouse
negative regulation of cell cycle g1 s phase transitionGO:1902807180.061
Mouse
myosin filament assemblyGO:003103420.060
negative regulation of fibroblast proliferationGO:0048147140.060
Mouse
regulation of skeletal muscle fiber developmentGO:0048742360.060
Mouse
methylationGO:00322591340.059
developmental pigmentationGO:0048066400.059
Mouse
nucleobase containing small molecule metabolic processGO:00550863520.059
Worm
divalent inorganic cation transportGO:00725111780.058
regulation of membrane potentialGO:00423911920.058
Mouse
blastocyst formationGO:0001825330.058
adherens junction assemblyGO:0034333220.058
Mouse
response to mycotoxinGO:001004610.058
morphogenesis of a branching epitheliumGO:00611381930.058
establishment of organelle localizationGO:00516561220.058
development of primary female sexual characteristicsGO:0046545730.058
Mouse
homeostasis of number of cellsGO:00488722100.058
carbohydrate derivative catabolic processGO:19011362310.057
Worm
t cell differentiationGO:00302171740.057
Mouse
negative regulation of homeostatic processGO:0032845710.056
Mouse
regulation of apoptotic dna fragmentationGO:190251050.056
sequestering of calcium ionGO:0051208180.056
divalent inorganic cation homeostasisGO:00725071380.055
regulation of cysteine type endopeptidase activityGO:2000116650.055
neuron migrationGO:00017641220.055
Mouse
calcium ion homeostasisGO:00550741270.055
nephron developmentGO:00720061090.055
Mouse
protein maturationGO:00516041760.055
small gtpase mediated signal transductionGO:0007264970.054
divalent metal ion transportGO:00708381720.054
positive regulation of nervous system developmentGO:00519622210.053
Mouse
regulation of cell cycle g1 s phase transitionGO:1902806350.053
Mouse
cd8 positive alpha beta t cell activationGO:003603790.053
Mouse
mammary gland epithelium developmentGO:0061180650.053
Mouse
response to organic cyclic compoundGO:00140701980.052
Mouse
ribonucleotide metabolic processGO:00092592910.052
Worm
myeloid cell differentiationGO:00300992330.052
development of primary sexual characteristicsGO:00451371430.052
Mouse
regulation of protein kinase activityGO:00458592320.051
organic cyclic compound catabolic processGO:19013612950.051
Worm
blastocyst developmentGO:0001824800.051
dna metabolic processGO:00062593030.050
nucleoside phosphate metabolic processGO:00067533380.050
Worm
fertilizationGO:00095661270.050
Mouse
positive regulation of neuron deathGO:1901216280.049
Mouse
hindbrain developmentGO:00309021280.049
Mouse
muscle cell migrationGO:0014812190.049
Mouse
defense response to virusGO:0051607680.049
myotube cell developmentGO:0014904600.049
Mouse
nucleoside phosphate catabolic processGO:19012922220.049
Worm
negative regulation of leukocyte apoptotic processGO:2000107310.049
Mouse
regulation of bindingGO:00510981110.048
neural nucleus developmentGO:0048857220.048
Mouse
cd8 positive alpha beta t cell differentiationGO:004337490.048
Mouse
mitochondrial outer membrane permeabilizationGO:0097345100.048
Mouse
signal transduction by p53 class mediatorGO:0072331510.048
Mouse
purine nucleotide metabolic processGO:00061633020.048
Worm
signal transduction in absence of ligandGO:0038034550.048
protein localization to mitochondrionGO:0070585150.048
Mouse
mesonephric tubule developmentGO:0072164940.047
Mouse
er nucleus signaling pathwayGO:0006984270.047
positive regulation of peptidyl serine phosphorylationGO:0033138250.047
Mouse
axon regenerationGO:0031103120.047
Mouse
digestive tract morphogenesisGO:00485461470.047
Mouse
hepatocyte apoptotic processGO:0097284110.047
Mouse
protein methylationGO:0006479810.046
positive regulation of gtp catabolic processGO:0033126850.046
Worm
cell fate commitmentGO:00451652100.046
Mouse
gonad developmentGO:00084061410.046
Mouse
endomembrane system organizationGO:00102561470.046
regulation of intracellular transportGO:00323861590.046
chromatin modificationGO:00165681870.045
ribonucleoside triphosphate metabolic processGO:00091992200.045
Worm
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.045
dephosphorylationGO:00163111290.045
Mouse
cellular calcium ion homeostasisGO:00068741190.045
mesenchymal cell differentiationGO:00487621070.045
Mouse
positive regulation of cell migrationGO:00303351090.045
Mouse
negative regulation of cytoplasmic transportGO:1903650290.045
Mouse
regulation of nucleotide metabolic processGO:00061401690.044
Worm
oocyte differentiationGO:0009994350.044
Mouse
focal adhesion assemblyGO:0048041190.044
Mouse
regulation of transferase activityGO:00513382630.044
positive regulation of striated muscle tissue developmentGO:0045844310.044
Mouse
defense response to other organismGO:00985421970.044
skin morphogenesisGO:0043589380.044
Mouse
regulation of mitotic cell cycleGO:00073461260.044
Mouse
apoptotic nuclear changesGO:003026290.043
genitalia developmentGO:0048806370.043
organonitrogen compound catabolic processGO:19015652640.043
Worm
glycoprotein metabolic processGO:00091001160.043
Mouse
regulation of protein bindingGO:0043393600.042
apoptotic dna fragmentationGO:000630970.042
cell maturationGO:00484691270.042
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.042
ovulation cycleGO:0042698590.042
Mouse
second messenger mediated signalingGO:0019932730.042
vagina developmentGO:0060068110.042
regulation of gtp catabolic processGO:00331241130.042
Worm
organ growthGO:00352651170.042
Mouse
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.041
axonogenesisGO:00074092740.041
Mouse
melanocyte differentiationGO:0030318250.041
Mouse
nucleoside triphosphate metabolic processGO:00091412300.041
Worm
protein oligomerizationGO:0051259670.041
Mouse
translationGO:0006412930.041
hair follicle morphogenesisGO:0031069290.041
Mouse
mapk cascadeGO:00001652810.041
compound eye developmentGO:004874910.041
establishment of protein localization to mitochondrionGO:0072655110.041
Mouse
cell substrate adherens junction assemblyGO:0007045190.041
Mouse
regulation of lymphocyte activationGO:00512492400.040
development of secondary sexual characteristicsGO:0045136110.040
Mouse
cellular response to oxidative stressGO:0034599760.040
Mouse
positive regulation of neuron differentiationGO:00456661410.040
Mouse
regulation of cytoplasmic transportGO:19036491120.039
locomotory behaviorGO:00076261950.039
inflammatory responseGO:00069542440.039
adherens junction organizationGO:0034332280.039
Mouse
purine nucleoside triphosphate catabolic processGO:00091462030.039
Worm
cellular response to radiationGO:0071478280.039
response to unfolded proteinGO:0006986210.039

Bak1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.435
cancerDOID:16200.435
immune system cancerDOID:006008300.315
organ system cancerDOID:005068600.315
hematologic cancerDOID:253100.196
leukemiaDOID:124000.191
gastrointestinal system cancerDOID:311900.150
intestinal cancerDOID:1015500.117
colon cancerDOID:21900.117
large intestine cancerDOID:567200.117
colon carcinomaDOID:152000.117
colorectal cancerDOID:925600.117
disease of anatomical entityDOID:700.073
musculoskeletal system diseaseDOID:1700.073