Mus musculus

182 known processes

Brca2

breast cancer 2

(Aliases: AI256696,AW045498,RAB163,Fancd1)

Brca2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742071.000
dna repairGO:00062811071.000
dna recombinationGO:0006310921.000
double strand break repairGO:0006302480.999
double strand break repair via homologous recombinationGO:0000724210.999
response to ionizing radiationGO:0010212420.996
dna metabolic processGO:00062593030.996
meiosis iGO:0007127600.995
regulation of cell cycle g2 m phase transitionGO:1902749100.994
meiotic cell cycle processGO:1903046770.987
meiotic chromosome segregationGO:0045132190.980
cell cycle checkpointGO:0000075470.979
recombinational repairGO:0000725210.978
negative regulation of cell cycle phase transitionGO:1901988480.965
reciprocal dna recombinationGO:0035825160.956
cellular response to radiationGO:0071478280.954
regulation of cell cycle processGO:00105641600.946
cellular response to ionizing radiationGO:0071479110.937
regulation of cell cycle phase transitionGO:1901987770.937
meiotic cell cycleGO:00513211220.936
negative regulation of cell cycleGO:00457861230.935
response to radiationGO:00093141650.923
reciprocal meiotic recombinationGO:0007131160.917
negative regulation of mitotic cell cycle phase transitionGO:1901991450.917
intrinsic apoptotic signaling pathwayGO:00971931320.913
mitotic cell cycle checkpointGO:0007093310.912
regulation of mitotic cell cycleGO:00073461260.908
dna dependent dna replicationGO:0006261240.901
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.867
mitotic cell cycleGO:00002781950.866
mitotic cell cycle processGO:19030471590.859
cellular response to gamma radiationGO:007148040.857
regulation of mitotic cell cycle phase transitionGO:1901990730.857
chromosome segregationGO:0007059480.856
negative regulation of mitotic cell cycleGO:0045930580.854
signal transduction involved in dna damage checkpointGO:007242230.845
dna integrity checkpointGO:0031570280.832
signal transduction by p53 class mediatorGO:0072331510.829
regulation of cell cycleGO:00517262810.815
dna damage checkpointGO:0000077260.805
regulation of cell divisionGO:0051302760.786
organelle fissionGO:00482851700.777
mitotic g2 dna damage checkpointGO:000709580.764
intra s dna damage checkpointGO:003157340.745
meiotic nuclear divisionGO:00071261150.742
double strand break repair via nonhomologous end joiningGO:0006303100.726
organic cyclic compound catabolic processGO:19013612950.722
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.704
signal transduction involved in dna integrity checkpointGO:007240130.682
regulation of response to dna damage stimulusGO:2001020340.676
signal transduction involved in cell cycle checkpointGO:007239530.674
cellular macromolecule catabolic processGO:00442652060.664
telomere maintenanceGO:0000723190.625
chromosome organization involved in meiosisGO:0070192390.624
non recombinational repairGO:0000726100.600
dna replicationGO:0006260520.597
negative regulation of cell cycle processGO:0010948690.590
chromosome separationGO:0051304140.588
mitotic sister chromatid segregationGO:0000070140.584
positive regulation of histone h3 k9 methylationGO:005157440.579
atp catabolic processGO:0006200550.564
dna dependent dna replication maintenance of fidelityGO:004500530.561
mitotic sister chromatid cohesionGO:000706410.545
regulation of cellular amine metabolic processGO:0033238200.545
regulation of cellular response to stressGO:00801351590.540
regulation of histone h3 k4 methylationGO:0051569120.538
nuclear divisionGO:00002801580.536
anatomical structure homeostasisGO:00602491450.534
dna catabolic processGO:0006308190.534
purine nucleotide catabolic processGO:00061952110.525
purine ribonucleoside triphosphate catabolic processGO:00092071990.502
postreplication repairGO:000630150.501
sister chromatid segregationGO:0000819200.500
ribonucleoside catabolic processGO:00424542060.498
purine ribonucleotide metabolic processGO:00091502900.495
positive regulation of histone h3 k4 methylationGO:005157150.495
purine nucleoside catabolic processGO:00061522050.488
glycosyl compound catabolic processGO:19016582060.479
cell agingGO:0007569350.474
histone lysine methylationGO:0034968500.472
positive regulation of cellular amino acid metabolic processGO:004576430.460
signal transduction involved in mitotic dna damage checkpointGO:190240230.456
cellular amino acid metabolic processGO:00065201030.454
macromolecule methylationGO:00434141200.449
heterocycle catabolic processGO:00467002800.446
blastocyst growthGO:0001832230.445
cellular ketone metabolic processGO:0042180840.442
peptidyl lysine modificationGO:0018205770.442
Human
negative regulation of fatty acid metabolic processGO:0045922100.439
positive regulation of cell cycleGO:0045787920.434
chromatin organizationGO:00063252060.427
Human
regulation of dna recombinationGO:0000018340.426
purine nucleoside monophosphate catabolic processGO:0009128580.423
apoptotic signaling pathwayGO:00971903060.415
cellular response to abiotic stimulusGO:0071214560.413
regulation of cellular amino acid metabolic processGO:000652150.411
covalent chromatin modificationGO:00165691630.402
Human
telomere cappingGO:001623340.402
mitotic spindle checkpointGO:007117490.390
cell divisionGO:00513011200.387
somatic diversification of immune receptorsGO:0002200530.386
g2 m transition of mitotic cell cycleGO:0000086200.386
female meiosis chromosome segregationGO:001632110.385
response to caffeineGO:003100060.375
purine ribonucleotide catabolic processGO:00091542080.374
regulation of g2 m transition of mitotic cell cycleGO:0010389100.371
regulation of cellular catabolic processGO:00313292420.368
mitotic cell cycle arrestGO:007185040.361
translesion synthesisGO:001998510.354
negative regulation of histone h3 k9 methylationGO:005157340.353
regulation of mitosisGO:0007088290.353
nucleoside phosphate catabolic processGO:19012922220.346
chromatin modificationGO:00165681870.340
Human
nucleoside monophosphate metabolic processGO:0009123850.339
somatic diversification of immune receptors via somatic mutationGO:000256680.335
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.334
regulation of histone methylationGO:0031060300.326
positive regulation of cell cycle phase transitionGO:1901989170.323
negative regulation of dna replicationGO:000815640.323
protein catabolic processGO:00301632210.319
regulation of organelle organizationGO:00330432890.318
female gamete generationGO:0007292740.318
nucleoside monophosphate catabolic processGO:0009125590.317
amine metabolic processGO:0009308450.315
purine nucleotide metabolic processGO:00061633020.315
regulation of cellular ketone metabolic processGO:0010565660.311
negative regulation of cellular protein catabolic processGO:1903363220.311
mitotic recombinationGO:000631230.306
nucleoside triphosphate metabolic processGO:00091412300.305
positive regulation of apoptotic processGO:00430652170.305
synapsisGO:0007129340.304
dna duplex unwindingGO:003250870.303
nucleic acid phosphodiester bond hydrolysisGO:0090305490.299
dna geometric changeGO:003239270.296
somatic recombination of immunoglobulin gene segmentsGO:0016447420.293
histone h4 k16 acetylationGO:004398430.292
production of molecular mediator of immune responseGO:00024401030.291
positive regulation of cellular amine metabolic processGO:003324050.291
aromatic compound catabolic processGO:00194392860.287
immunoglobulin mediated immune responseGO:0016064690.287
cellular amine metabolic processGO:0044106440.283
cell cycle g2 m phase transitionGO:0044839200.280
ribonucleotide metabolic processGO:00092592910.279
ribonucleoside metabolic processGO:00091192450.278
glycosyl compound metabolic processGO:19016572460.273
nucleoside triphosphate catabolic processGO:00091432050.272
proteolysis involved in cellular protein catabolic processGO:00516031470.271
histone h4 k20 methylationGO:003477080.266
regulation of histone h3 k9 methylationGO:005157080.262
dna biosynthetic processGO:0071897220.247
metaphase anaphase transition of mitotic cell cycleGO:000709190.240
regulation of chromosome organizationGO:0033044830.237
purine ribonucleoside triphosphate metabolic processGO:00092052200.237
gene silencingGO:0016458380.232
cellular nitrogen compound catabolic processGO:00442702800.230
regulation of fatty acid biosynthetic processGO:0042304120.229
negative regulation of nuclear divisionGO:0051784190.229
histone h3 k9 methylationGO:0051567170.229
heterochromatin organizationGO:007082840.228
cell activation involved in immune responseGO:00022631260.224
protein autophosphorylationGO:0046777610.224
purine nucleoside metabolic processGO:00422782410.222
g2 dna damage checkpointGO:003157280.217
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.216
negative regulation of cell divisionGO:0051782240.216
response to gamma radiationGO:0010332220.214
chromatin silencingGO:0006342150.210
signal transduction involved in mitotic dna integrity checkpointGO:190240330.209
negative regulation of cell proliferationGO:00082852960.207
Human
methylationGO:00322591340.206
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.205
g1 s transition of mitotic cell cycleGO:0000082570.204
histone methylationGO:0016571710.203
mitotic nuclear divisionGO:0007067480.203
centrosome cycleGO:0007098230.203
Human
histone h3 k4 methylationGO:0051568230.202
nucleobase containing small molecule metabolic processGO:00550863520.199
cellular response to organonitrogen compoundGO:00714171450.193
mitotic sister chromatid separationGO:005130690.192
negative regulation of cellular amine metabolic processGO:003323910.190
negative regulation of protein processingGO:0010955790.187
purine nucleoside triphosphate metabolic processGO:00091442260.185
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.182
immunoglobulin productionGO:0002377730.179
negative regulation of cellular protein metabolic processGO:00322692470.179
ribonucleoside triphosphate metabolic processGO:00091992200.177
peptidyl amino acid modificationGO:00181933360.177
Human
cellular protein catabolic processGO:00442571550.177
dna methylationGO:0006306430.176
ribonucleotide catabolic processGO:00092612080.173
dna catabolic process exonucleolyticGO:000073830.172
reactive oxygen species metabolic processGO:0072593840.172
mitotic spindle assembly checkpointGO:000709470.171
response to organic cyclic compoundGO:00140701980.169
ribonucleoside monophosphate metabolic processGO:0009161800.169
dna damage response signal transduction by p53 class mediatorGO:0030330190.167
ubiquitin dependent protein catabolic processGO:00065111290.165
dna modificationGO:0006304500.162
purine ribonucleoside catabolic processGO:00461302050.162
purine nucleoside triphosphate catabolic processGO:00091462030.162
regulation of metaphase anaphase transition of cell cycleGO:190209990.160
b cell mediated immunityGO:0019724710.159
regulation of dna methylationGO:0044030120.158
negative regulation of cellular component organizationGO:00511291940.158
purine containing compound metabolic processGO:00725213110.158
mitochondrial dna repairGO:004350430.153
cell cycle arrestGO:0007050370.152
positive regulation of mitotic cell cycle phase transitionGO:1901992170.152
protein methylationGO:0006479810.152
protein oligomerizationGO:0051259670.150
nucleoside metabolic processGO:00091162460.149
response to x rayGO:0010165110.147
regulation of transferase activityGO:00513382630.146
atp metabolic processGO:0046034750.146
negative regulation of chromosome organizationGO:2001251300.145
centrosome organizationGO:0051297260.144
Human
negative regulation of protein metabolic processGO:00512482820.143
response to purine containing compoundGO:0014074280.143
maintenance of locationGO:0051235890.142
negative regulation of protein modification processGO:00314001630.141
spindle checkpointGO:0031577120.140
b cell activationGO:00421131610.140
nucleotide catabolic processGO:00091662170.140
leukocyte mediated immunityGO:00024431740.140
positive regulation of histone methylationGO:0031062160.139
leukocyte activation involved in immune responseGO:00023661260.138
oocyte developmentGO:0048599330.135
fatty acid biosynthetic processGO:0006633410.135
microtubule cytoskeleton organizationGO:00002261570.135
Human
carbohydrate derivative catabolic processGO:19011362310.134
regulation of reactive oxygen species metabolic processGO:2000377400.133
somatic diversification of immunoglobulinsGO:0016445430.131
organophosphate catabolic processGO:00464342320.131
attachment of spindle microtubules to kinetochoreGO:000860840.131
stem cell differentiationGO:00488632680.130
histone h3 acetylationGO:0043966140.127
Human
macromolecule catabolic processGO:00090572810.126
dna endoreduplicationGO:004202340.125
cell cycle g1 s phase transitionGO:0044843570.125
lipid biosynthetic processGO:00086101790.124
negative regulation of histone methylationGO:0031061100.124
ribonucleoside triphosphate catabolic processGO:00092031990.122
purine containing compound catabolic processGO:00725232130.120
ribose phosphate metabolic processGO:00196932910.118
microtubule organizing center organizationGO:0031023280.117
Human
isotype switchingGO:0045190360.115
germ cell developmentGO:00072811850.113
dosage compensation by inactivation of x chromosomeGO:000904870.112
male meiosisGO:0007140370.111
regulation of attachment of spindle microtubules to kinetochoreGO:005198830.111
regulation of protein processingGO:0070613960.110
negative regulation of cellular catabolic processGO:0031330470.110
protein alkylationGO:0008213810.109
leukocyte proliferationGO:00706611720.107
organonitrogen compound catabolic processGO:19015652640.107
purine nucleoside monophosphate metabolic processGO:0009126810.107
positive regulation of protein modification processGO:00314012990.106
protein maturationGO:00516041760.106
cellular response to organic cyclic compoundGO:0071407870.105
regulation of neuron differentiationGO:00456642810.105
ribonucleoside monophosphate catabolic processGO:0009158570.103
response to organonitrogen compoundGO:00102432460.102
metaphase plate congressionGO:005131020.101
positive regulation of cytokine productionGO:00018191740.101
nucleotide metabolic processGO:00091173320.101
oocyte differentiationGO:0009994350.100
spindle assembly involved in mitosisGO:009030740.100
lymphocyte activation involved in immune responseGO:0002285930.100
nucleoside catabolic processGO:00091642060.099
regulation of mitotic sister chromatid segregationGO:0033047120.099
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.099
regulation of nuclear cell cycle dna replicationGO:003326220.098
protein processingGO:00164851630.097
proteasomal protein catabolic processGO:0010498980.097
cell cycle comprising mitosis without cytokinesisGO:003330110.096
cellular response to light stimulusGO:0071482190.096
regulation of proteasomal protein catabolic processGO:0061136460.095
regulation of kinase activityGO:00435492490.094
dna packagingGO:0006323300.093
regulation of histone modificationGO:0031056560.093
protein modification by small protein conjugation or removalGO:00706472070.092
lymphocyte mediated immunityGO:00024491390.090
regulation of histone acetylationGO:0035065190.089
regulation of proteolysisGO:00301621640.088
histone acetylationGO:0016573410.088
Human
modification dependent protein catabolic processGO:00199411330.088
lymphocyte differentiationGO:00300982420.086
response to alkaloidGO:0043279340.086
cellular response to cytokine stimulusGO:00713451890.086
regulation of chromatin modificationGO:1903308570.084
microtubule based processGO:00070172360.084
Human
regulation of protein maturationGO:1903317960.084
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.083
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.082
regulation of chromatin organizationGO:1902275570.081
negative regulation of organelle organizationGO:0010639900.081
positive regulation of neuron deathGO:1901216280.081
regulation of protein acetylationGO:1901983220.079
organism emergence from protective structureGO:007168440.078
t cell activationGO:00421102890.078
protein acylationGO:0043543640.076
Human
negative regulation of mitotic sister chromatid segregationGO:003304870.075
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697730.075
regulation of protein serine threonine kinase activityGO:00719001570.074
regulation of cellular protein catabolic processGO:1903362610.074
intracellular signal transduction involved in g1 dna damage checkpointGO:190240030.074
internal peptidyl lysine acetylationGO:0018393420.073
Human
microtubule cytoskeleton organization involved in mitosisGO:190285040.073
dna alkylationGO:0006305430.072
protein localization to organelleGO:00333651850.071
nuclear dna replicationGO:003326030.071
phosphatidylinositol 3 phosphate biosynthetic processGO:003609260.071
regulation of fatty acid metabolic processGO:0019217280.071
positive regulation of mitotic cell cycleGO:0045931410.070
female meiotic divisionGO:0007143210.068
histone modificationGO:00165701590.068
Human
purine ribonucleoside metabolic processGO:00461282410.066
regulation of protein kinase activityGO:00458592320.066
positive regulation of histone modificationGO:0031058280.065
regulation of cell morphogenesis involved in differentiationGO:00107691510.065
negative regulation of gene expression epigeneticGO:0045814150.065
peptidyl serine modificationGO:0018209830.065
negative regulation of protein maturationGO:1903318790.064
gland developmentGO:00487323300.064
Human
protein modification by small protein conjugationGO:00324461870.064
intracellular mrna localizationGO:000829840.063
spindle assembly checkpointGO:007117390.063
positive regulation of kinase activityGO:00336741550.062
positive regulation of response to dna damage stimulusGO:2001022140.061
adaptive immune responseGO:00022501550.060
dna conformation changeGO:0071103370.060
positive regulation of chromatin modificationGO:1903310280.060
negative regulation of proteolysisGO:0045861740.060
lymphocyte proliferationGO:00466511640.059
regulation of cytoskeleton organizationGO:00514931220.059
regulation of lymphocyte activationGO:00512492400.059
somatic cell dna recombinationGO:0016444510.059
protein ubiquitinationGO:00165671710.059
positive regulation of g2 m transition of mitotic cell cycleGO:001097150.058
negative regulation of protein serine threonine kinase activityGO:0071901490.057
regulation of double strand break repair via homologous recombinationGO:001056920.057
negative regulation of lipid metabolic processGO:0045833300.057
cellular response to antibioticGO:007123640.056
organic acid biosynthetic processGO:0016053860.053
cohesin localization to chromatinGO:007192110.053
regulation of protein ubiquitinationGO:0031396520.053
carboxylic acid biosynthetic processGO:0046394860.053
regulation of sister chromatid cohesionGO:000706350.053
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.053
negative regulation of mammary gland epithelial cell proliferationGO:003360030.052
Human
response to light stimulusGO:00094161350.052
multicellular organism growthGO:00352641610.052
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.052
positive regulation of dna repairGO:004573930.052
positive regulation of protein acetylationGO:190198590.051
regulation of cell activationGO:00508652890.051
purine ribonucleoside monophosphate catabolic processGO:0009169570.051
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.050
immune effector processGO:00022523210.050
sister chromatid cohesionGO:0007062120.050
regulation of sister chromatid segregationGO:0033045130.050
regulation of chromosome segregationGO:0051983210.050
b cell differentiationGO:0030183780.049
rna catabolic processGO:0006401290.049
regulation of t cell apoptotic processGO:0070232280.048
genetic imprintingGO:0071514270.048
negative regulation of protein catabolic processGO:0042177360.048
neuron apoptotic processGO:00514021420.047
nucleoside phosphate metabolic processGO:00067533380.047
regulation of histone h4 acetylationGO:009023930.047
development of primary sexual characteristicsGO:00451371430.047
mitotic g1 dna damage checkpointGO:003157140.047
regulation of protein localizationGO:00328802310.047
nucleocytoplasmic transportGO:00069131390.046
protein polyubiquitinationGO:0000209330.046
angiogenesisGO:00015252010.046
small molecule biosynthetic processGO:00442831320.046
regulation of protein stabilityGO:0031647520.046
spindle organizationGO:0007051280.045
blastocyst developmentGO:0001824800.045
b cell activation involved in immune responseGO:0002312500.045
regulation of peptidyl lysine acetylationGO:2000756220.045
cytokine productionGO:00018163190.044
positive regulation of cell deathGO:00109422240.043
base excision repairGO:000628490.043
regulation of cellular component biogenesisGO:00440871810.043
regulation of mitotic sister chromatid separationGO:0010965120.043
regulation of b cell activationGO:0050864810.042
positive regulation of transferase activityGO:00513471670.042
histone h3 k9 acetylationGO:004397050.041
regulation of leukocyte proliferationGO:00706631210.041
female genitalia morphogenesisGO:004880730.041
negative regulation of protein phosphorylationGO:00019331260.041
monocarboxylic acid biosynthetic processGO:0072330610.041
mitotic chromosome condensationGO:000707610.041
somite developmentGO:0061053810.040
dna ligationGO:000626630.040
somatic hypermutation of immunoglobulin genesGO:001644670.040
regulation of cohesin localization to chromatinGO:007192210.039
response to nutrient levelsGO:00316671090.039
negative regulation of fatty acid biosynthetic processGO:004571770.039
meiotic chromosome separationGO:005130750.038
spermatid differentiationGO:00485151150.038
negative regulation of mitotic sister chromatid separationGO:200081670.038
negative regulation of phosphorylationGO:00423261660.037
positive regulation of organelle organizationGO:00106381280.037
negative regulation of phosphate metabolic processGO:00459361840.037
regulation of transcription by chromatin organizationGO:003440100.037
negative regulation of mitotic metaphase anaphase transitionGO:004584170.036
regulation of dna replicationGO:0006275170.036
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:003114590.036
positive regulation of protein autophosphorylationGO:003195440.035
cell fate commitmentGO:00451652100.035
intracellular protein transportGO:00068862040.035
negative regulation of dna recombinationGO:0045910130.035
homeostasis of number of cellsGO:00488722100.035
cell type specific apoptotic processGO:00972852680.035
negative regulation of cellular amino acid metabolic processGO:004576300.035
negative regulation of reactive oxygen species metabolic processGO:2000378100.035
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.035
positive regulation of programmed cell deathGO:00430682180.034
positive regulation of protein ubiquitinationGO:0031398270.034
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042110.034
negative regulation of metaphase anaphase transition of cell cycleGO:190210080.033
phosphatidylinositol metabolic processGO:0046488450.033
actin filament organizationGO:00070151130.033
hatchingGO:003518840.032
regulation of protein modification by small protein conjugation or removalGO:1903320570.032
regulation of anatomical structure sizeGO:00900661780.032
positive regulation of cell cycle processGO:0090068610.032
replicative senescenceGO:009039920.032
regulation of lipid metabolic processGO:00192161180.032
regulation of lipid biosynthetic processGO:0046890540.031
positive regulation of angiogenesisGO:0045766460.031
protein import into nucleusGO:0006606950.031
regulation of dna repairGO:000628290.031
protein targetingGO:00066051430.031
negative regulation of sister chromatid segregationGO:003304670.031
positive regulation of hydrolase activityGO:00513451480.031
regulation of bindingGO:00510981110.030
positive regulation of chromosome organizationGO:2001252330.030
multicellular organismal homeostasisGO:00488711640.030
purine ribonucleoside monophosphate metabolic processGO:0009167800.030
monocarboxylic acid metabolic processGO:00327871910.030
dendrite developmentGO:00163581150.030
regulation of hydrolase activityGO:00513362460.030
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.029
regulation of cell cycle g1 s phase transitionGO:1902806350.029
chemotaxisGO:00069352470.029
positive regulation of histone acetylationGO:003506680.029
extrinsic apoptotic signaling pathwayGO:00971911260.029
blood vessel morphogenesisGO:00485142850.028
cellular response to growth factor stimulusGO:00713631970.028
regulation of neuron apoptotic processGO:00435231220.028
regulation of lymphocyte proliferationGO:00506701170.028
negative regulation of transferase activityGO:0051348850.028
spindle assemblyGO:0051225130.028
cellular lipid metabolic processGO:00442553230.028
digestive system developmentGO:00551232000.027
negative regulation of chromosome segregationGO:005198590.027
regulation of cellular component sizeGO:00325351210.027
regulation of apoptotic signaling pathwayGO:20012331970.027
regulation of cell cycle arrestGO:0071156120.027
embryonic organ morphogenesisGO:00485622760.027
negative regulation of kinase activityGO:0033673810.027
regulation of cell projection organizationGO:00313442060.026
regulation of protein catabolic processGO:00421761080.026
histone mrna metabolic processGO:000833430.026
immature b cell differentiationGO:0002327100.026
response to extracellular stimulusGO:00099911270.026
response to inorganic substanceGO:0010035960.026

Brca2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.998
Human
cancerDOID:16200.995
Human
organ system cancerDOID:005068600.995
Human
thoracic cancerDOID:509300.923
Human
hematopoietic system diseaseDOID:7400.889
Human
immune system diseaseDOID:291400.889
Human
disease of anatomical entityDOID:700.889
Human
anemiaDOID:235500.769
Human
breast cancerDOID:161200.763
Human
bone marrow diseaseDOID:496100.552
Human
aplastic anemiaDOID:1244900.552
Human
endocrine gland cancerDOID:17000.275
Human
pancreatic cancerDOID:179300.174
Human
immune system cancerDOID:006008300.159
hematologic cancerDOID:253100.159
large intestine cancerDOID:567200.055
intestinal cancerDOID:1015500.055
gastrointestinal system cancerDOID:311900.055
colorectal cancerDOID:925600.042
colon cancerDOID:21900.042
congenital hypoplastic anemiaDOID:134200.032
Human
fanconi s anemiaDOID:1363600.032
Human
physical disorderDOID:008001500.026