Mus musculus

149 known processes

Casp1

caspase 1

(Aliases: Il1bc,ICE)

Casp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of interleukin 1 secretionGO:0050716141.000
i kappab kinase nf kappab signalingGO:0007249850.999
positive regulation of interleukin 1 beta productionGO:0032731160.998
defense response to other organismGO:00985421970.998
Fly
regulation of defense responseGO:00313472330.997
interleukin 1 secretionGO:0050701160.994
cellular response to molecule of bacterial originGO:0071219830.994
cytokine productionGO:00018163190.994
cellular response to interferon betaGO:0035458210.993
regulation of cytokine productionGO:00018172660.993
regulation of interleukin 8 productionGO:003267730.991
interleukin 1 beta productionGO:0032611300.991
positive regulation of defense responseGO:00313491240.991
Fly
negative regulation of necroptotic processGO:006054690.991
Mouse
cellular response to biotic stimulusGO:0071216920.989
defense response to virusGO:0051607680.989
Fly
positive regulation of innate immune responseGO:0045089800.986
Fly
release of cytochrome c from mitochondriaGO:0001836230.984
Mouse
interleukin 1 productionGO:0032612310.984
cellular response to cytokine stimulusGO:00713451890.983
response to molecule of bacterial originGO:00022371430.983
regulation of protein transportGO:00512231630.982
response to lipopolysaccharideGO:00324961280.981
regulation of protein targetingGO:1903533610.981
regulation of response to biotic stimulusGO:0002831380.978
Fly
cellular response to lipidGO:00713961450.978
Mouse
positive regulation of cysteine type endopeptidase activityGO:2001056390.976
Mouse Fly
pyroptosisGO:007026980.975
protein import into nucleusGO:0006606950.968
cellular response to lipopolysaccharideGO:0071222770.965
regulation of establishment of protein localizationGO:00702011810.964
negative regulation of cytokine productionGO:0001818840.963
regulation of chemokine productionGO:0032642300.963
regulation of interleukin 1 productionGO:0032652260.961
activation of immune responseGO:00022531380.961
activation of innate immune responseGO:0002218560.960
positive regulation of interleukin 1 beta secretionGO:0050718140.959
regulation of apoptotic dna fragmentationGO:190251050.957
Mouse
regulation of cytoplasmic transportGO:19036491120.953
regulation of intracellular protein transportGO:0033157820.951
interleukin 1 alpha secretionGO:005070330.951
protein importGO:00170381010.950
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.949
Mouse
defense response to bacteriumGO:00427421190.947
Fly
defense response to gram positive bacteriumGO:0050830500.943
negative regulation of phosphorus metabolic processGO:00105631840.937
Mouse
glial cell apoptotic processGO:003434930.935
Mouse
interleukin 8 productionGO:003263740.935
positive regulation of cytokine productionGO:00018191740.930
establishment of protein localization to organelleGO:00725941180.918
positive regulation of interleukin 1 alpha productionGO:003273040.917
positive regulation of secretionGO:00510471300.916
nuclear transportGO:00511691390.915
interleukin 1 beta secretionGO:0050702160.910
positive regulation of interleukin 1 alpha secretionGO:005071730.909
t cell proliferationGO:00420981200.906
Mouse
cytokine secretionGO:0050663720.902
regulation of protein localizationGO:00328802310.898
regulation of defense response to virus by hostGO:005069180.896
Fly
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.891
regulation of type i interferon productionGO:0032479220.889
regulation of peptidase activityGO:0052547960.886
Mouse Fly
single organism nuclear importGO:1902593950.885
positive regulation of secretion by cellGO:19035321140.885
apoptotic dna fragmentationGO:000630970.884
Mouse
positive regulation of endopeptidase activityGO:0010950430.880
Mouse Fly
protein autoprocessingGO:001654020.880
Worm Fly
regulation of lymphocyte activationGO:00512492400.878
Mouse
positive regulation of interleukin 8 secretionGO:200048410.877
positive regulation of interleukin 6 secretionGO:200077810.873
membrane hyperpolarizationGO:0060081210.872
interspecies interaction between organismsGO:0044419830.872
positive regulation of interleukin 1 productionGO:0032732170.863
negative regulation of transferase activityGO:0051348850.863
Mouse
positive regulation of cytokine secretionGO:0050715410.861
regulation of intracellular transportGO:00323861590.852
regulation of endopeptidase activityGO:0052548890.849
Mouse Fly
positive regulation of protein secretionGO:0050714520.846
regulation of nucleocytoplasmic transportGO:0046822730.842
negative regulation of protein modification processGO:00314001630.832
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.831
Mouse Fly
regulation of interleukin 18 productionGO:003266130.826
cytoplasmic transportGO:00164822340.826
positive regulation of programmed cell deathGO:00430682180.821
Mouse Rat Fly
positive regulation of peptidase activityGO:0010952490.821
Mouse Fly
regulation of interferon alpha productionGO:003264750.817
cytokine biosynthetic processGO:0042089680.813
regulation of execution phase of apoptosisGO:190011790.812
Mouse
leukocyte activation involved in immune responseGO:00023661260.811
regulation of interleukin 1 alpha productionGO:003265040.802
protein secretionGO:00093061110.801
regulation of antibacterial peptide productionGO:000278610.800
Fly
nucleocytoplasmic transportGO:00069131390.796
secondary metabolic processGO:0019748180.792
Fly
regulation of interleukin 6 productionGO:0032675550.789
negative regulation of phosphate metabolic processGO:00459361840.787
Mouse
jnk cascadeGO:0007254720.786
mitochondrion organizationGO:00070051340.784
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.782
Mouse
regulation of interleukin 1 beta productionGO:0032651250.782
antibacterial peptide productionGO:000277820.778
Fly
adaptive immune responseGO:00022501550.777
regulation of lymphocyte proliferationGO:00506701170.773
Mouse
activation of cysteine type endopeptidase activityGO:0097202270.772
Mouse Fly
apoptotic mitochondrial changesGO:0008637480.769
Mouse
positive regulation of jnk cascadeGO:0046330460.767
regulation of cysteine type endopeptidase activityGO:2000116650.766
Mouse Fly
apoptotic signaling pathwayGO:00971903060.765
Mouse Fly
innate immune responseGO:00450871570.763
Fly
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.752
Mouse Fly
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.745
leukocyte proliferationGO:00706611720.744
Mouse
defense response to gram negative bacteriumGO:0050829280.743
Fly
negative regulation of phosphorylationGO:00423261660.740
Mouse
intracellular protein transportGO:00068862040.740
regulation of interleukin 8 secretionGO:200048220.739
inflammatory responseGO:00069542440.736
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.730
Mouse
b cell proliferationGO:0042100530.726
Mouse
toxin transportGO:1901998380.726
response to endoplasmic reticulum stressGO:0034976530.724
Mouse
organic cyclic compound catabolic processGO:19013612950.723
Mouse
positive regulation of proteolysisGO:0045862850.714
Mouse Fly
zymogen activationGO:0031638410.714
Mouse Fly
dna catabolic process endonucleolyticGO:0000737150.705
Mouse
negative regulation of protein transportGO:0051224460.703
b cell activationGO:00421131610.690
Mouse
positive regulation of protein transportGO:0051222930.684
regulation of autophagyGO:0010506300.677
regulation of stress activated mapk cascadeGO:0032872690.673
defense response to protozoanGO:0042832250.670
purine nucleoside metabolic processGO:00422782410.667
protein modification by small protein conjugationGO:00324461870.663
regulation of antimicrobial peptide biosynthetic processGO:000280510.657
Fly
positive regulation of chemokine biosynthetic processGO:004508060.654
negative regulation of protein phosphorylationGO:00019331260.652
Mouse
regulation of proteolysisGO:00301621640.649
Mouse Fly
regulation of secretion by cellGO:19035302490.643
cellular response to interferon gammaGO:0071346250.640
dna metabolic processGO:00062593030.636
Mouse
antimicrobial peptide biosynthetic processGO:000277720.636
Fly
pigment metabolic processGO:0042440320.636
Fly
morphogenesis of embryonic epitheliumGO:00163311590.634
Mouse
regulation of interferon beta productionGO:0032648130.633
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126740.629
Fly
amide transportGO:00428861380.629
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.628
positive regulation of lymphocyte activationGO:00512511400.623
regulation of defense response to bacteriumGO:190042430.621
Fly
rac protein signal transductionGO:0016601130.613
regulation of apoptotic signaling pathwayGO:20012331970.606
Mouse Fly
cellular nitrogen compound catabolic processGO:00442702800.606
Mouse
peptide transportGO:00158331330.600
positive regulation of interleukin 10 secretionGO:200118110.598
type i interferon productionGO:0032606290.595
heterocycle catabolic processGO:00467002800.588
Mouse
membrane depolarizationGO:0051899640.587
mitochondrial depolarizationGO:005188260.587
phagocytosisGO:0006909660.586
Worm
cellular response to peptidoglycanGO:007122440.575
engulfment of apoptotic cellGO:004365230.569
Worm
negative regulation of nik nf kappab signalingGO:190122320.568
regulation of response to woundingGO:19030341890.566
aromatic compound catabolic processGO:00194392860.565
Mouse
tube formationGO:00351481400.564
Mouse
regulation of interleukin 10 secretionGO:200117940.563
cellular response to dna damage stimulusGO:00069742070.562
Mouse
protein maturationGO:00516041760.561
pattern recognition receptor signaling pathwayGO:0002221470.553
regulation of interleukin 1 beta secretionGO:0050706150.550
extrinsic apoptotic signaling pathwayGO:00971911260.547
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126930.545
Fly
sperm individualizationGO:000729110.544
Fly
regulation of protein serine threonine kinase activityGO:00719001570.544
Mouse
regulation of leukocyte proliferationGO:00706631210.539
Mouse
protein localization to nucleusGO:00345041210.535
detection of molecule of bacterial originGO:003249020.532
negative regulation of lymphocyte proliferationGO:0050672450.530
Mouse
regulation of multi organism processGO:00439001110.529
Fly
regulation of sequence specific dna binding transcription factor activityGO:00510901060.518
lymphocyte homeostasisGO:0002260640.517
Mouse
response to atpGO:003319880.517
organonitrogen compound catabolic processGO:19015652640.516
interleukin 18 productionGO:003262140.515
regulation of transferase activityGO:00513382630.514
Mouse
lipopolysaccharide mediated signaling pathwayGO:0031663250.513
regulation of necroptotic processGO:0060544100.510
Mouse
protein localization to organelleGO:00333651850.509
positive regulation of production of molecular mediator of immune responseGO:0002702450.508
Fly
positive regulation of stress activated mapk cascadeGO:0032874480.503
protein processingGO:00164851630.499
positive regulation of apoptotic processGO:00430652170.492
Mouse Rat Fly
myeloid cell differentiationGO:00300992330.488
Mouse
b cell mediated immunityGO:0019724710.486
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.482
autophagyGO:0006914450.481
positive regulation of release of cytochrome c from mitochondriaGO:009020050.480
positive regulation of protein localization to nucleusGO:1900182300.478
natural killer cell activationGO:0030101440.472
actin filament polymerizationGO:0030041440.471
immunoglobulin mediated immune responseGO:0016064690.468
regulation of prostaglandin endoperoxide synthase activityGO:006058420.467
response to organic cyclic compoundGO:00140701980.467
positive regulation of nf kappab transcription factor activityGO:0051092300.463
compound eye developmentGO:004874910.460
Fly
positive regulation of interleukin 8 productionGO:003275720.459
keratinocyte differentiationGO:0030216480.458
Mouse
regulation of cellular catabolic processGO:00313292420.456
regulation of adaptive immune responseGO:0002819900.454
lymphocyte proliferationGO:00466511640.453
Mouse
regulation of kinase activityGO:00435492490.449
Mouse
necroptotic processGO:0070266210.448
Mouse
regulation of interleukin 10 productionGO:0032653210.448
protein modification by small protein conjugation or removalGO:00706472070.445
positive regulation of antibacterial peptide biosynthetic processGO:000696310.444
Fly
positive regulation of interleukin 6 productionGO:0032755370.444
regulation of t cell activationGO:00508631700.443
Mouse
regulation of interleukin 1 secretionGO:0050704150.432
regulation of production of molecular mediator of immune responseGO:0002700650.432
Fly
regulation of protein kinase activityGO:00458592320.431
Mouse
positive regulation of t cell proliferationGO:0042102520.430
hepatocyte apoptotic processGO:0097284110.429
Mouse
regulation of neuron deathGO:19012141340.429
Mouse
interferon beta productionGO:0032608160.426
positive regulation of antimicrobial peptide productionGO:000222510.422
Fly
positive regulation of transcription factor import into nucleusGO:004299380.420
negative regulation of intracellular protein transportGO:0090317270.403
glycosyl compound catabolic processGO:19016582060.402
positive regulation of erk1 and erk2 cascadeGO:0070374470.401
negative regulation of protein serine threonine kinase activityGO:0071901490.395
Mouse
tumor necrosis factor productionGO:0032640500.394
nuclear importGO:0051170950.394
blood vessel morphogenesisGO:00485142850.392
Mouse
positive regulation of hydrolase activityGO:00513451480.390
Mouse Fly
epidermis developmentGO:00085441870.389
Mouse
regulation of protein import into nucleusGO:0042306520.388
rho protein signal transductionGO:0007266320.387
interferon beta biosynthetic processGO:004535040.387
neural tube developmentGO:00219151600.386
Mouse
negative regulation of immune system processGO:00026832090.383
Mouse
positive regulation of interferon gamma productionGO:0032729390.381
interleukin 6 secretionGO:007260430.378
negative regulation of protein localization to nucleusGO:1900181230.372
positive regulation of interleukin 18 productionGO:003274120.370
interferon gamma productionGO:0032609670.367
cellular amino acid metabolic processGO:00065201030.365
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.365
Mouse Fly
negative regulation of t cell proliferationGO:0042130380.364
Mouse
response to interferon betaGO:0035456220.364
response to organophosphorusGO:0046683220.364
negative regulation of cell cycleGO:00457861230.363
Mouse
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.359
positive regulation of leukocyte proliferationGO:0070665730.357
regulation of cell cycleGO:00517262810.357
Mouse
myeloid leukocyte differentiationGO:00025731190.356
Mouse
regulation of mitochondrial membrane potentialGO:0051881170.355
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.352
inflammatory response to woundingGO:009059440.350
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.345
Fly
regulation of transcription factor import into nucleusGO:0042990240.341
regulation of cell activationGO:00508652890.340
Mouse
b cell homeostasisGO:0001782340.337
Mouse
positive regulation of mapk cascadeGO:00434101700.336
regulation of leukocyte apoptotic processGO:2000106560.335
Mouse
regulation of inflammatory response to antigenic stimulusGO:0002861210.330
positive regulation of nitric oxide synthase biosynthetic processGO:005177060.329
positive regulation of neuron deathGO:1901216280.327
Mouse
intrinsic apoptotic signaling pathwayGO:00971931320.326
Mouse
cytokine metabolic processGO:0042107710.324
regulation of hydrolase activityGO:00513362460.318
Mouse Fly
regulation of b cell activationGO:0050864810.314
Mouse
interleukin 10 secretionGO:007260840.307
cell fate commitmentGO:00451652100.304
Mouse
protein complex localizationGO:0031503190.304
macromolecule catabolic processGO:00090572810.295
Mouse Worm
regulation of reactive oxygen species biosynthetic processGO:190342620.291
neuron deathGO:00709971540.289
Mouse
positive regulation by symbiont of defense related host nitric oxide productionGO:005234710.287
regulation of t cell proliferationGO:0042129920.287
Mouse
response to dexamethasoneGO:007154880.286
Mouse
response to dsrnaGO:0043331300.286
regulation of acute inflammatory responseGO:0002673270.282
chemokine productionGO:0032602340.276
positive regulation of cell deathGO:00109422240.274
Mouse Rat Fly
cell type specific apoptotic processGO:00972852680.274
Mouse Fly
regulation of tumor necrosis factor productionGO:0032680490.272
negative regulation of protein import into nucleusGO:0042308210.270
cytokine mediated signaling pathwayGO:00192211150.269
epithelial tube morphogenesisGO:00605623030.268
Mouse
phenol containing compound metabolic processGO:0018958600.268
Fly
regulation of cytokine secretionGO:0050707610.265
negative regulation of interleukin 6 productionGO:0032715170.265
spermatogenesisGO:00072832840.263
Fly
purine containing compound metabolic processGO:00725213110.262
t cell homeostasisGO:0043029350.262
Mouse
er nucleus signaling pathwayGO:0006984270.262
Mouse
ribonucleoside catabolic processGO:00424542060.262
immunoglobulin productionGO:0002377730.259
protein targetingGO:00066051430.259
protein catabolic processGO:00301632210.258
Worm
positive regulation of chemokine productionGO:0032722220.258
cellular response to dexamethasone stimulusGO:007154980.257
Mouse
reactive nitrogen species metabolic processGO:200105700.252
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.249
Mouse
cellular amine metabolic processGO:0044106440.248
cellular response to hormone stimulusGO:00328701500.248
Mouse
antibacterial humoral responseGO:001973180.246
Fly
regulation of necrotic cell deathGO:0010939130.246
Mouse
immune effector processGO:00022523210.245
Fly
cellular response to oxidative stressGO:0034599760.243
Mouse
leukocyte apoptotic processGO:0071887710.243
Mouse
carbohydrate derivative catabolic processGO:19011362310.243
regulation of actin cytoskeleton organizationGO:0032956840.242
antibacterial peptide biosynthetic processGO:000278020.239
Fly
positive regulation of interleukin 10 productionGO:0032733120.239
wound healing involved in inflammatory responseGO:000224640.239
positive regulation of chemokine secretionGO:009019740.239
positive regulation of t cell activationGO:00508701010.235
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.233
regulation of inflammatory responseGO:00507271470.231
positive regulation of intracellular protein transportGO:0090316420.230
negative regulation of cytoplasmic transportGO:1903650290.230
nitrogen compound transportGO:00717052710.228
skin developmentGO:00435882200.226
Mouse
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.225
Mouse
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.225
positive regulation of cytoplasmic transportGO:1903651400.220
activation of mapk activity involved in innate immune responseGO:003541920.220
cellularizationGO:000734910.220
Fly
regulation of cytokine biosynthetic processGO:0042035590.218
t cell activationGO:00421102890.214
Mouse
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.213
Mouse
leukocyte differentiationGO:00025213420.213
Mouse
multicellular organismal homeostasisGO:00488711640.211
negative regulation of activated t cell proliferationGO:004600770.210
Mouse
helper t cell enhancement of adaptive immune responseGO:003539710.207
myeloid dendritic cell activation involved in immune responseGO:000227720.207
innate immune response activating cell surface receptor signaling pathwayGO:000222040.207
negative regulation of molecular functionGO:00440922580.207
Mouse
nucleic acid phosphodiester bond hydrolysisGO:0090305490.207
Mouse
mapk cascadeGO:00001652810.201
positive regulation of apoptotic signaling pathwayGO:2001235950.200
Mouse Fly
positive regulation of cellular amino acid metabolic processGO:004576430.199
developmental maturationGO:00217001930.193
Fly
antigen processing and presentation of peptide antigenGO:0048002290.193
negative regulation of hydrolase activityGO:0051346710.192
negative regulation of erk1 and erk2 cascadeGO:0070373210.192
thymocyte apoptotic processGO:0070242190.191
Mouse
regulation of body fluid levelsGO:00508781620.191
positive regulation of lymphocyte proliferationGO:0050671700.191
protein oligomerizationGO:0051259670.189
Fly
stress activated protein kinase signaling cascadeGO:0031098810.189
purine ribonucleoside triphosphate metabolic processGO:00092052200.188
antimicrobial peptide productionGO:000277520.187
Fly
regulation of release of cytochrome c from mitochondriaGO:0090199110.186
induction by organism of immune response of other organism involved in symbiotic interactionGO:005255810.186
regulation of protein secretionGO:0050708820.182
response to tumor necrosis factorGO:0034612260.182
homeostasis of number of cellsGO:00488722100.180
Mouse
growth of symbiont in hostGO:0044117230.180
positive regulation of immune effector processGO:00026991070.179
Fly
regulation of nucleoside metabolic processGO:00091181300.179
carboxylic acid transportGO:00469421000.179
epithelial tube formationGO:00721751300.179
Mouse
regulation of protein localization to nucleusGO:1900180600.176
regulation of toll like receptor 2 signaling pathwayGO:003413530.175
negative regulation of intracellular signal transductionGO:19025321670.172
organic acid transportGO:00158491010.171
nucleoside triphosphate metabolic processGO:00091412300.169
pinocytosisGO:000690760.168
cell surface pattern recognition receptor signaling pathwayGO:000275220.168
response to defense related host nitric oxide productionGO:005256520.167
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.167
regulation of peptide transportGO:0090087910.167
dna catabolic processGO:0006308190.166
Mouse
toll like receptor signaling pathwayGO:0002224380.166
regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042830.164
myoblast differentiationGO:0045445520.163
interferon alpha productionGO:003260770.163
reactive oxygen species metabolic processGO:0072593840.163
regulation of defense response to virusGO:0050688180.163
Fly
b cell activation involved in immune responseGO:0002312500.162
response to radiationGO:00093141650.160
Mouse
symbiosis encompassing mutualism through parasitismGO:0044403830.159
regulation of antibacterial peptide biosynthetic processGO:000280810.157
Fly
regulation of b cell proliferationGO:0030888390.157
Mouse
t cell migrationGO:0072678190.155
gtp catabolic processGO:00061841430.154
lymphocyte activation involved in immune responseGO:0002285930.154
regulation of antimicrobial humoral responseGO:000275930.153
Fly
actin polymerization or depolymerizationGO:0008154540.153
cellular response to topologically incorrect proteinGO:0035967250.151
Mouse
response to peptideGO:19016521360.149
regulation of thymocyte apoptotic processGO:0070243140.148
Mouse
negative regulation of macrophage apoptotic processGO:200011030.148
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.146
Mouse
regulation of cellular ketone metabolic processGO:0010565660.146
purine containing compound catabolic processGO:00725232130.145
interleukin 1 alpha productionGO:003261050.145
reactive oxygen species biosynthetic processGO:190340980.145
response to defense related nitric oxide production by other organism involved in symbiotic interactionGO:005255120.145
cellular response to organonitrogen compoundGO:00714171450.144
negative regulation of leukocyte proliferationGO:0070664460.144
Mouse
negative regulation of toll like receptor signaling pathwayGO:0034122140.141
transcription factor import into nucleusGO:0042991260.140
regulation of secretionGO:00510462740.138
regulation of cellular response to stressGO:00801351590.138
purine nucleoside catabolic processGO:00061522050.136
positive regulation of kinase activityGO:00336741550.136
regulation of jnk cascadeGO:0046328620.135
positive regulation of defense response to bacteriumGO:190042610.133
Fly
sensory perception of soundGO:0007605970.133
Mouse
amine metabolic processGO:0009308450.132
cellular response to glucocorticoid stimulusGO:0071385130.132
Mouse
cellular response to alcoholGO:0097306230.131
Mouse
cellular response to corticosteroid stimulusGO:0071384130.130
Mouse
regulation of interferon gamma productionGO:0032649570.128
ribonucleotide catabolic processGO:00092612080.128
response to bacterial lipoproteinGO:003249340.127
angiogenesisGO:00015252010.127
Mouse
regulation of mapk cascadeGO:00434082480.126
positive regulation of actin filament polymerizationGO:0030838260.125
regulation of growth of symbiont in hostGO:0044126190.125
negative regulation of t cell activationGO:0050868650.125
Mouse
positive regulation of interferon beta biosynthetic processGO:004535930.125
positive regulation of lymphocyte mediated immunityGO:0002708620.124
interleukin 10 productionGO:0032613230.124
nucleotide metabolic processGO:00091173320.122
regulation of antigen processing and presentationGO:0002577100.121
response to host immune responseGO:005257230.121
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.120
positive regulation of antimicrobial humoral responseGO:000276020.119
Fly
negative regulation of interferon gamma productionGO:0032689180.118
positive regulation of reactive oxygen species metabolic processGO:2000379110.118
nucleoside triphosphate catabolic processGO:00091432050.118
positive regulation of cytoskeleton organizationGO:0051495490.117
production of molecular mediator of immune responseGO:00024401030.115
Fly
regulation of nucleotide metabolic processGO:00061401690.114
connective tissue replacement involved in inflammatory response wound healingGO:000224830.113
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.113
positive regulation of protein kinase activityGO:00458601440.113
cation transportGO:00068123990.113
regulation of ion transportGO:00432692150.111
interleukin 8 secretionGO:007260630.110
cellular component disassembly involved in execution phase of apoptosisGO:000692190.109
Mouse
regulation of ras protein signal transductionGO:00465781140.109
purine nucleoside triphosphate metabolic processGO:00091442260.108
muscle system processGO:00030121410.106
myotube differentiationGO:00149021050.105
Rat
inflammatory cell apoptotic processGO:0006925110.105
modulation by symbiont of host immune responseGO:005255310.104
protein ubiquitinationGO:00165671710.103
nucleobase containing small molecule metabolic processGO:00550863520.103
positive regulation of cellular amine metabolic processGO:003324050.103
negative regulation of protein metabolic processGO:00512482820.103
Mouse
response to organonitrogen compoundGO:00102432460.103
myotube cell developmentGO:0014904600.102
organonitrogen compound biosynthetic processGO:19015661920.101
Fly
acute inflammatory responseGO:0002526410.101
purine ribonucleotide catabolic processGO:00091542080.099
regulation of response to cytokine stimulusGO:0060759230.098
stress activated mapk cascadeGO:0051403800.098
glycosyl compound metabolic processGO:19016572460.097
cellular ketone metabolic processGO:0042180840.097
negative regulation of cell proliferationGO:00082852960.097
Mouse Fly
adhesion of symbiont to hostGO:004440680.095
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.095
regulation of neutrophil chemotaxisGO:0090022140.095
purine ribonucleoside catabolic processGO:00461302050.094
negative regulation of mapk cascadeGO:0043409650.094
interleukin 17 productionGO:0032620110.094
lymphocyte apoptotic processGO:0070227540.093
Mouse
response to peptidoglycanGO:003249490.092
positive regulation of mitotic cell cycleGO:0045931410.092
modulation of growth of symbiont involved in interaction with hostGO:0044144190.091
modulation by organism of defense response of other organism involved in symbiotic interactionGO:005225510.091
cellular chemical homeostasisGO:00550822150.091
body fluid secretionGO:0007589530.091
positive regulation of cellular component biogenesisGO:0044089940.090
anion transportGO:00068201770.090
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.089
organ or tissue specific immune responseGO:0002251130.088
positive regulation of interferon alpha productionGO:003272740.088
endocytosisGO:00068971680.087
Worm
interleukin 6 productionGO:0032635580.087
regulation of protein processingGO:0070613960.087
positive regulation of homeostatic processGO:0032846640.087
regulation of cytoskeleton organizationGO:00514931220.086
actin cytoskeleton organizationGO:00300362200.086
regulation of t cell mediated immunityGO:0002709340.085
macropinocytosisGO:004435140.085
response to interleukin 1GO:0070555110.084
regulation of organelle organizationGO:00330432890.084
negative regulation of growthGO:0045926990.083
myeloid dendritic cell activationGO:0001773250.083
response to alcoholGO:0097305480.083
Mouse

Casp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.164
disease of cellular proliferationDOID:1456600.164
organ system cancerDOID:005068600.139