IMP: Integrative Multi-species Prediction

Mus musculus

20 known processes

Cct5

chaperonin containing Tcp1, subunit 5 (epsilon)

(Aliases: mKIAA0098,TCPE,Ccte)

Ensembl: ENSMUSG00000022234
Entrez: 12465
UniProtKB: P80316

Process Predictions
Disease Predictions

Cct5 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
spindle assembly involved in mitosis	GO:0090307	4	1.000	Fly
binding of sperm to zona pellucida	GO:0007339	34	0.999
sperm egg recognition	GO:0035036	37	0.992
microtubule cytoskeleton organization involved in mitosis	GO:1902850	4	0.985	Fly
cell cell recognition	GO:0009988	44	0.973
toxin transport	GO:1901998	38	0.944
microtubule cytoskeleton organization	GO:0000226	157	0.660	Fly
cytoplasmic microtubule organization	GO:0031122	14	0.648
cell recognition	GO:0008037	83	0.633
fertilization	GO:0009566	127	0.621
organelle assembly	GO:0070925	177	0.618	Fly
protein folding	GO:0006457	28	0.611	Yeast
mitotic nuclear division	GO:0007067	48	0.570	Fly
single fertilization	GO:0007338	82	0.514
microtubule based process	GO:0007017	236	0.476	Fly
translational initiation	GO:0006413	24	0.402
cytoplasmic translational initiation	GO:0002183	3	0.372
translation	GO:0006412	93	0.363
nucleobase containing small molecule metabolic process	GO:0055086	352	0.314
protein refolding	GO:0042026	1	0.309
genitalia development	GO:0048806	37	0.303	Worm
nuclear division	GO:0000280	158	0.299	Fly
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.280
gonad development	GO:0008406	141	0.251	Worm
mitotic cell cycle process	GO:1903047	159	0.232	Fly
mitotic cell cycle	GO:0000278	195	0.194	Fly
mitotic spindle organization	GO:0007052	10	0.179	Fly
ribonucleoside catabolic process	GO:0042454	206	0.161
nucleoside phosphate metabolic process	GO:0006753	338	0.159
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.155
cellular nitrogen compound catabolic process	GO:0044270	280	0.153
phagocytosis	GO:0006909	66	0.153
development of primary sexual characteristics	GO:0045137	143	0.148	Worm
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.148
organelle fission	GO:0048285	170	0.128	Fly
cell type specific apoptotic process	GO:0097285	268	0.126
purine nucleoside catabolic process	GO:0006152	205	0.122
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.118
negative regulation of cellular protein metabolic process	GO:0032269	247	0.117
trna metabolic process	GO:0006399	11	0.117
positive regulation of cell death	GO:0010942	224	0.116
oocyte anterior posterior axis specification	GO:0007314	2	0.115
spindle assembly	GO:0051225	13	0.114	Fly
nucleotide catabolic process	GO:0009166	217	0.114
endocytosis	GO:0006897	168	0.112	Worm
nucleotide metabolic process	GO:0009117	332	0.106
spindle organization	GO:0007051	28	0.101	Fly
ribonucleotide catabolic process	GO:0009261	208	0.100
oocyte construction	GO:0007308	2	0.099
trna aminoacylation for protein translation	GO:0006418	1	0.099
ribose phosphate metabolic process	GO:0019693	291	0.096
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.094
respiratory system development	GO:0060541	190	0.093
dna templated transcriptional preinitiation complex assembly	GO:0070897	4	0.091
pore complex assembly	GO:0046931	3	0.089
ribonucleotide metabolic process	GO:0009259	291	0.086
regulation of cell cycle	GO:0051726	281	0.082
proteasome assembly	GO:0043248	1	0.082
organic cyclic compound catabolic process	GO:1901361	295	0.076
germ cell development	GO:0007281	185	0.074
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.074
organophosphate catabolic process	GO:0046434	232	0.072
purine ribonucleoside catabolic process	GO:0046130	205	0.068
interaction with host	GO:0051701	22	0.064
negative regulation of phosphorus metabolic process	GO:0010563	184	0.060
nucleoside phosphate catabolic process	GO:1901292	222	0.059
aromatic compound catabolic process	GO:0019439	286	0.058
leukocyte migration	GO:0050900	124	0.056
ribonucleoside metabolic process	GO:0009119	245	0.053
protein localization to nucleus	GO:0034504	121	0.052
purine containing compound metabolic process	GO:0072521	311	0.049
female gamete generation	GO:0007292	74	0.047
nucleoside triphosphate metabolic process	GO:0009141	230	0.047
regulation of establishment of protein localization	GO:0070201	181	0.046
receptor mediated endocytosis	GO:0006898	51	0.045	Worm
oogenesis	GO:0048477	56	0.043
glycosyl compound metabolic process	GO:1901657	246	0.043
carbohydrate derivative catabolic process	GO:1901136	231	0.043
purine nucleotide metabolic process	GO:0006163	302	0.043
purine nucleotide biosynthetic process	GO:0006164	65	0.041
regulation of protein localization	GO:0032880	231	0.039
epithelial cell proliferation	GO:0050673	174	0.038
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.038
regulation of cellular component biogenesis	GO:0044087	181	0.036
maturation of ssu rrna	GO:0030490	1	0.036
interspecies interaction between organisms	GO:0044419	83	0.035
myeloid cell apoptotic process	GO:0033028	22	0.035
leukocyte apoptotic process	GO:0071887	71	0.035
purine containing compound catabolic process	GO:0072523	213	0.033
nucleoside triphosphate catabolic process	GO:0009143	205	0.033
regulation of rna splicing	GO:0043484	37	0.032
regulation of leukocyte apoptotic process	GO:2000106	56	0.029
dna templated transcription initiation	GO:0006352	13	0.029
regulation of translation	GO:0006417	71	0.029
positive regulation of hydrolase activity	GO:0051345	148	0.029
regulation of ion transmembrane transport	GO:0034765	119	0.028
regulation of myeloid cell apoptotic process	GO:0033032	19	0.028
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.028
chemotaxis	GO:0006935	247	0.027
nucleoside metabolic process	GO:0009116	246	0.027
purine ribonucleoside metabolic process	GO:0046128	241	0.026
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.026
positive regulation of cellular component biogenesis	GO:0044089	94	0.026
oocyte differentiation	GO:0009994	35	0.026
amine metabolic process	GO:0009308	45	0.025
oocyte axis specification	GO:0007309	2	0.025
cellular amino acid metabolic process	GO:0006520	103	0.025
regulation of cell cycle process	GO:0010564	160	0.025
regulation of organ morphogenesis	GO:2000027	144	0.024
cellular amine metabolic process	GO:0044106	44	0.023
negative regulation of retinal cell programmed cell death	GO:0046671	2	0.022
regulation of ion transport	GO:0043269	215	0.022
purine ribonucleotide metabolic process	GO:0009150	290	0.022
rna splicing	GO:0008380	54	0.022
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.021
cell division	GO:0051301	120	0.021
regulation of cellular response to stress	GO:0080135	159	0.021
nuclear transport	GO:0051169	139	0.021
negative regulation of protein metabolic process	GO:0051248	282	0.020
chromatin organization	GO:0006325	206	0.020
regulation of cell division	GO:0051302	76	0.020
cellular response to cytokine stimulus	GO:0071345	189	0.020
cation transmembrane transport	GO:0098655	266	0.020
embryonic organ morphogenesis	GO:0048562	276	0.020
pole plasm assembly	GO:0007315	2	0.020
negative regulation of cell proliferation	GO:0008285	296	0.019
nucleoside catabolic process	GO:0009164	206	0.019
regulation of kinase activity	GO:0043549	249	0.019
purine ribonucleotide catabolic process	GO:0009154	208	0.019
regulation of stem cell division	GO:2000035	4	0.019
positive regulation of transcription initiation from rna polymerase ii promoter	GO:0060261	5	0.018
axon guidance	GO:0007411	141	0.018
purine nucleotide catabolic process	GO:0006195	211	0.018
purine nucleoside metabolic process	GO:0042278	241	0.018
negative regulation of molecular function	GO:0044092	258	0.018
nuclear import	GO:0051170	95	0.017
centrosome cycle	GO:0007098	23	0.017
glycosyl compound catabolic process	GO:1901658	206	0.017
organonitrogen compound catabolic process	GO:1901565	264	0.017
striated muscle tissue development	GO:0014706	293	0.017
muscle tissue development	GO:0060537	308	0.017
heterocycle catabolic process	GO:0046700	280	0.017
oocyte development	GO:0048599	33	0.016
regulation of purine nucleotide catabolic process	GO:0033121	122	0.016
centrosome organization	GO:0051297	26	0.016
negative regulation of protein phosphorylation	GO:0001933	126	0.016
regulation of hydrolase activity	GO:0051336	246	0.015
inflammatory cell apoptotic process	GO:0006925	11	0.015
positive regulation of protein localization to nucleus	GO:1900182	30	0.015
rna processing	GO:0006396	105	0.015
protein import into nucleus	GO:0006606	95	0.015
regulation of organelle organization	GO:0033043	289	0.015
ion transmembrane transport	GO:0034220	361	0.015
transmembrane transport	GO:0055085	412	0.015
macrophage apoptotic process	GO:0071888	7	0.014
regulation of intracellular transport	GO:0032386	159	0.014
regulation of cellular component size	GO:0032535	121	0.014
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.014
regulation of transmembrane transport	GO:0034762	128	0.014
protein maturation	GO:0051604	176	0.014
regulation of multi organism process	GO:0043900	111	0.014
positive regulation of apoptotic process	GO:0043065	217	0.014
cell maturation	GO:0048469	127	0.014
amino acid activation	GO:0043038	1	0.014
blastocyst development	GO:0001824	80	0.014
regulation of cellular ketone metabolic process	GO:0010565	66	0.014
nucleoside phosphate biosynthetic process	GO:1901293	79	0.013
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.013
carbohydrate derivative biosynthetic process	GO:1901137	183	0.013
atp catabolic process	GO:0006200	55	0.013
regulation of epithelial cell proliferation	GO:0050678	141	0.013
atp metabolic process	GO:0046034	75	0.013
cellular protein complex assembly	GO:0043623	116	0.013
regulation of protein complex assembly	GO:0043254	83	0.013
organophosphate biosynthetic process	GO:0090407	122	0.013
regulation of mitotic cell cycle	GO:0007346	126	0.013
negative regulation of phosphate metabolic process	GO:0045936	184	0.013
developmental maturation	GO:0021700	193	0.013
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.013
regulation of cell motility	GO:2000145	236	0.012
lymphocyte proliferation	GO:0046651	164	0.012
regulation of cytoskeleton organization	GO:0051493	122	0.012
response to acid chemical	GO:0001101	111	0.012
regulation of cellular amino acid metabolic process	GO:0006521	5	0.012
regulation of dna templated transcription initiation	GO:2000142	7	0.012
regulation of intracellular protein transport	GO:0033157	82	0.012
protein import	GO:0017038	101	0.012
positive regulation of protein complex assembly	GO:0031334	45	0.012
hematopoietic progenitor cell differentiation	GO:0002244	143	0.012
regulation of gtp catabolic process	GO:0033124	113	0.012
positive regulation of gtp catabolic process	GO:0033126	85	0.011
regulation of protein transport	GO:0051223	163	0.011
neuron death	GO:0070997	154	0.011
detection of stimulus	GO:0051606	84	0.011
macromolecule catabolic process	GO:0009057	281	0.011
negative regulation of dephosphorylation	GO:0035305	9	0.011
organelle disassembly	GO:1903008	2	0.011
response to hypoxia	GO:0001666	58	0.011
response to inorganic substance	GO:0010035	96	0.011
blood circulation	GO:0008015	195	0.011
peptidyl amino acid modification	GO:0018193	336	0.011
paraxial mesodermal cell fate commitment	GO:0048343	2	0.011
reactive oxygen species biosynthetic process	GO:1903409	8	0.011
negative regulation of epithelial cell proliferation	GO:0050680	64	0.011
positive regulation of cellular amine metabolic process	GO:0033240	5	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.010
positive regulation of programmed cell death	GO:0043068	218	0.010
purine ribonucleoside monophosphate catabolic process	GO:0009169	57	0.010
regulation of cell growth	GO:0001558	91	0.010
trna aminoacylation	GO:0043039	1	0.010
macromolecule methylation	GO:0043414	120	0.010
negative regulation of intracellular signal transduction	GO:1902532	167	0.010
extracellular matrix organization	GO:0030198	147	0.010

Cct5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.070
disease of anatomical entity	DOID:7	0.070
neuropathy	DOID:870	0.017
central nervous system disease	DOID:331	0.012
motor neuritis	DOID:683	0.011
distal hereditary motor neuropathy	DOID:0050582	0.011
neurodegenerative disease	DOID:1289	0.011
motor neuron disease	DOID:231	0.011

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