IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Cirh1a

cirrhosis, autosomal recessive 1A (human)

(Aliases: Cirhin,Teg-292,Tex292,Naic)

Entrez: 21771
Ensembl: ENSMUSG00000041438
UniProtKB: Q8R2N2

Process Predictions
Disease Predictions

Cirh1a biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
maturation of ssu rrna	GO:0030490	1	0.883	Human Yeast
ribosome biogenesis	GO:0042254	20	0.703	Human Yeast
ncrna processing	GO:0034470	26	0.425	Human Yeast
rrna processing	GO:0006364	10	0.418	Human Yeast
regulation of exit from mitosis	GO:0007096	1	0.399
ribosomal small subunit biogenesis	GO:0042274	4	0.379	Human Yeast
rna processing	GO:0006396	105	0.237	Human Yeast
positive regulation of cellular respiration	GO:1901857	3	0.114
gonad development	GO:0008406	141	0.088
maturation of lsu rrna	GO:0000470	1	0.081
macromolecule methylation	GO:0043414	120	0.079
t cell activation	GO:0042110	289	0.077
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000466	1	0.067
endonucleolytic cleavage involved in rrna processing	GO:0000478	1	0.063
myeloid cell differentiation	GO:0030099	233	0.063
ossification	GO:0001503	216	0.062
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000462	1	0.056	Yeast
posttranscriptional regulation of gene expression	GO:0010608	155	0.055
negative regulation of cell proliferation	GO:0008285	296	0.055
embryonic skeletal system morphogenesis	GO:0048704	91	0.047
maturation of 5 8s rrna	GO:0000460	1	0.045
lymphocyte proliferation	GO:0046651	164	0.045
protein import into nucleus	GO:0006606	95	0.042
development of primary sexual characteristics	GO:0045137	143	0.042
establishment of protein localization to organelle	GO:0072594	118	0.041
camera type eye development	GO:0043010	266	0.041
regulation of cell cycle process	GO:0010564	160	0.040
nuclear transport	GO:0051169	139	0.039
cytoplasmic transport	GO:0016482	234	0.039
pore complex assembly	GO:0046931	3	0.038
protein targeting	GO:0006605	143	0.034
methylation	GO:0032259	134	0.034
respiratory system development	GO:0060541	190	0.034
positive regulation of transcription from rna polymerase i promoter	GO:0045943	3	0.033	Yeast
negative regulation of protein metabolic process	GO:0051248	282	0.032
nls bearing protein import into nucleus	GO:0006607	2	0.032
nucleolus organization	GO:0007000	5	0.032
negative regulation of protein modification process	GO:0031400	163	0.031
regulation of protein localization	GO:0032880	231	0.030
blastocyst formation	GO:0001825	33	0.029
dna dealkylation	GO:0035510	11	0.029
organelle assembly	GO:0070925	177	0.028
protein import	GO:0017038	101	0.028
regulation of establishment of protein localization	GO:0070201	181	0.028
mitotic cell cycle	GO:0000278	195	0.027
dephosphorylation	GO:0016311	129	0.027
amine metabolic process	GO:0009308	45	0.027
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.026
regulation of mitotic cell cycle	GO:0007346	126	0.025
dna templated transcription initiation	GO:0006352	13	0.025
ribose phosphate biosynthetic process	GO:0046390	59	0.024
nucleic acid phosphodiester bond hydrolysis	GO:0090305	49	0.024
negative regulation of molecular function	GO:0044092	258	0.023
t cell differentiation in thymus	GO:0033077	77	0.023
negative regulation of cellular protein metabolic process	GO:0032269	247	0.023
urogenital system development	GO:0001655	261	0.023
mapk cascade	GO:0000165	281	0.023
protein localization to nucleus	GO:0034504	121	0.021
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000463	1	0.021
mitotic nuclear division	GO:0007067	48	0.021
rrna metabolic process	GO:0016072	10	0.020	Human Yeast
cleavage involved in rrna processing	GO:0000469	1	0.020
regulation of protein targeting	GO:1903533	61	0.020
intracellular protein transport	GO:0006886	204	0.019
regulation of cellular respiration	GO:0043457	10	0.019
skeletal system morphogenesis	GO:0048705	203	0.019
purine nucleotide biosynthetic process	GO:0006164	65	0.019
multicellular organismal signaling	GO:0035637	91	0.019
cellular protein complex assembly	GO:0043623	116	0.019
multicellular organismal homeostasis	GO:0048871	164	0.018
leukocyte differentiation	GO:0002521	342	0.018
cellular amine metabolic process	GO:0044106	44	0.018
positive regulation of nucleocytoplasmic transport	GO:0046824	30	0.018
protein modification by small protein conjugation	GO:0032446	187	0.018
neuronal action potential	GO:0019228	54	0.018
mitochondrion organization	GO:0007005	134	0.017
positive regulation of protein transport	GO:0051222	93	0.017
regulation of nuclear division	GO:0051783	56	0.017
gland development	GO:0048732	330	0.017
transcription from rna polymerase i promoter	GO:0006360	13	0.017	Yeast
regulation of kinase activity	GO:0043549	249	0.017
single organismal cell cell adhesion	GO:0016337	131	0.017
tissue homeostasis	GO:0001894	115	0.017
single fertilization	GO:0007338	82	0.016
nucleoside metabolic process	GO:0009116	246	0.016
dna metabolic process	GO:0006259	303	0.016
single organism cell adhesion	GO:0098602	156	0.016
glycosyl compound metabolic process	GO:1901657	246	0.016
t cell differentiation	GO:0030217	174	0.016
mitochondrial membrane organization	GO:0007006	26	0.015
atp metabolic process	GO:0046034	75	0.015
dna templated transcriptional preinitiation complex assembly	GO:0070897	4	0.015
ribose phosphate metabolic process	GO:0019693	291	0.015
cell type specific apoptotic process	GO:0097285	268	0.015
protein dna complex subunit organization	GO:0071824	28	0.015
receptor mediated endocytosis	GO:0006898	51	0.015
female gamete generation	GO:0007292	74	0.015
positive regulation of programmed cell death	GO:0043068	218	0.015
organophosphate biosynthetic process	GO:0090407	122	0.015
chromatin modification	GO:0016568	187	0.015
single organism nuclear import	GO:1902593	95	0.015
purine ribonucleotide biosynthetic process	GO:0009152	59	0.015
retina development in camera type eye	GO:0060041	119	0.014
regulation of cell division	GO:0051302	76	0.014
purine containing compound biosynthetic process	GO:0072522	70	0.014
skeletal system development	GO:0001501	356	0.014
nuclear import	GO:0051170	95	0.014
nucleoside triphosphate metabolic process	GO:0009141	230	0.014
translation	GO:0006412	93	0.014
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.014
renal system development	GO:0072001	225	0.014
nucleobase containing small molecule metabolic process	GO:0055086	352	0.014
regulation of intracellular transport	GO:0032386	159	0.014
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.014
molting cycle	GO:0042303	90	0.014
negative regulation of phosphorus metabolic process	GO:0010563	184	0.014
embryonic organ morphogenesis	GO:0048562	276	0.013
regulation of epithelial cell proliferation	GO:0050678	141	0.013
organelle fission	GO:0048285	170	0.013
cellular response to cytokine stimulus	GO:0071345	189	0.013
action potential	GO:0001508	78	0.013
regulation of protein kinase activity	GO:0045859	232	0.013
cellular amino acid metabolic process	GO:0006520	103	0.013
positive regulation of phosphatase activity	GO:0010922	4	0.012
canonical wnt signaling pathway	GO:0060070	130	0.012
transcription initiation from rna polymerase i promoter	GO:0006361	4	0.012
positive regulation of apoptotic process	GO:0043065	217	0.012
nucleotide biosynthetic process	GO:0009165	78	0.012
regulation of mitosis	GO:0007088	29	0.012
nucleoside biosynthetic process	GO:0009163	21	0.012
regulation of protein transport	GO:0051223	163	0.012
forebrain development	GO:0030900	302	0.012
regulation of cell growth	GO:0001558	91	0.012
nucleocytoplasmic transport	GO:0006913	139	0.012
purine nucleotide metabolic process	GO:0006163	302	0.012
ribonucleotide metabolic process	GO:0009259	291	0.012
regulation of protein modification by small protein conjugation or removal	GO:1903320	57	0.012
negative regulation of dna replication	GO:0008156	4	0.012
ribonucleotide biosynthetic process	GO:0009260	59	0.012
cell division	GO:0051301	120	0.012
fertilization	GO:0009566	127	0.011
leukocyte proliferation	GO:0070661	172	0.011
regulation of protein ubiquitination	GO:0031396	52	0.011
cell recognition	GO:0008037	83	0.011
regulation of protein stability	GO:0031647	52	0.011
nucleoside phosphate metabolic process	GO:0006753	338	0.011
metaphase plate congression	GO:0051310	2	0.011
rna phosphodiester bond hydrolysis endonucleolytic	GO:0090502	10	0.011
cell adhesion	GO:0007155	329	0.011
trna wobble base modification	GO:0002097	2	0.011
cellular ketone metabolic process	GO:0042180	84	0.011
branching morphogenesis of an epithelial tube	GO:0048754	159	0.011
endocytosis	GO:0006897	168	0.010
regulation of organ morphogenesis	GO:2000027	144	0.010
canonical wnt signaling pathway involved in negative regulation of apoptotic process	GO:0044336	4	0.010
regulation of protein catabolic process	GO:0042176	108	0.010
regulation of nucleocytoplasmic transport	GO:0046822	73	0.010
regulation of protein localization to nucleus	GO:1900180	60	0.010
regulation of cell cycle	GO:0051726	281	0.010

Cirh1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
eye disease	DOID:5614	0.025
nervous system disease	DOID:863	0.025
eye and adnexa disease	DOID:1492	0.025
disease of anatomical entity	DOID:7	0.025
sensory system disease	DOID:0050155	0.025
retinal disease	DOID:5679	0.025
retinal degeneration	DOID:8466	0.015

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network