| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.594 | |
| dna metabolic process | GO:0006259 | 303 | 0.520 | |
| dna repair | GO:0006281 | 107 | 0.363 | |
| recombinational repair | GO:0000725 | 21 | 0.334 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.326 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.226 | Fly |
| mrna metabolic process | GO:0016071 | 84 | 0.191 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.176 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.171 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.171 | |
| female meiosis i | GO:0007144 | 7 | 0.171 | Fly |
| nuclear division | GO:0000280 | 158 | 0.168 | Mouse Worm Fly |
| mitotic cell cycle | GO:0000278 | 195 | 0.164 | Worm Fly |
| heterocycle catabolic process | GO:0046700 | 280 | 0.148 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.147 | |
| chromatin modification | GO:0016568 | 187 | 0.130 | |
| mrna processing | GO:0006397 | 63 | 0.119 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.115 | |
| deoxyribonucleotide biosynthetic process | GO:0009263 | 6 | 0.112 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.111 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.111 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.110 | |
| dna dependent dna replication | GO:0006261 | 24 | 0.107 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.102 | |
| meiosis i | GO:0007127 | 60 | 0.100 | Mouse Fly |
| g1 s transition of mitotic cell cycle | GO:0000082 | 57 | 0.099 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.097 | |
| organelle fission | GO:0048285 | 170 | 0.094 | Mouse Worm Fly |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.086 | |
| chromatin organization | GO:0006325 | 206 | 0.085 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.083 | Fly |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 43 | 0.082 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.077 | |
| regulation of spindle organization | GO:0090224 | 2 | 0.076 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.072 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.071 | |
| cell division | GO:0051301 | 120 | 0.069 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.069 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.067 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.066 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.065 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.064 | Mouse Worm Fly |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.063 | |
| rna processing | GO:0006396 | 105 | 0.060 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.060 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.058 | |
| deoxyribonucleotide metabolic process | GO:0009262 | 14 | 0.057 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.055 | Worm |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.055 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.055 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.055 | |
| double strand break repair | GO:0006302 | 48 | 0.053 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.053 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.051 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.051 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.051 | |
| microtubule based process | GO:0007017 | 236 | 0.049 | Fly |
| nuclear dna replication | GO:0033260 | 3 | 0.048 | |
| regulation of protein complex disassembly | GO:0043244 | 28 | 0.047 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.046 | |
| dna recombination | GO:0006310 | 92 | 0.044 | |
| gonad development | GO:0008406 | 141 | 0.044 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.044 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.044 | |
| regulation of protein localization | GO:0032880 | 231 | 0.043 | |
| protein ubiquitination | GO:0016567 | 171 | 0.043 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.043 | Fly |
| protein import | GO:0017038 | 101 | 0.041 | |
| gene silencing | GO:0016458 | 38 | 0.041 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.040 | |
| intracellular protein transport | GO:0006886 | 204 | 0.040 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 79 | 0.038 | |
| positive regulation of intracellular transport | GO:0032388 | 70 | 0.037 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.037 | Worm |
| negative regulation of molecular function | GO:0044092 | 258 | 0.037 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.037 | |
| regulation of mrna metabolic process | GO:1903311 | 43 | 0.037 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.036 | Fly |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.036 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.036 | |
| nuclear transport | GO:0051169 | 139 | 0.035 | |
| base excision repair | GO:0006284 | 9 | 0.035 | |
| cellular response to lipid | GO:0071396 | 145 | 0.035 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.034 | |
| negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator | GO:1902254 | 8 | 0.033 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.033 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.032 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.032 | Fly |
| forebrain development | GO:0030900 | 302 | 0.032 | |
| negative regulation of purine nucleotide metabolic process | GO:1900543 | 16 | 0.032 | |
| genitalia development | GO:0048806 | 37 | 0.032 | |
| interspecies interaction between organisms | GO:0044419 | 83 | 0.031 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.031 | Fly |
| response to oxidative stress | GO:0006979 | 123 | 0.031 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.030 | |
| histone modification | GO:0016570 | 159 | 0.030 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.030 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.029 | |
| regulation of protein import into nucleus | GO:0042306 | 52 | 0.029 | |
| protein complex disassembly | GO:0043241 | 40 | 0.029 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.029 | |
| negative regulation of hydrolase activity | GO:0051346 | 71 | 0.029 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.028 | Fly |
| response to acid chemical | GO:0001101 | 111 | 0.028 | |
| cell cycle checkpoint | GO:0000075 | 47 | 0.028 | |
| dna replication | GO:0006260 | 52 | 0.028 | |
| leukocyte homeostasis | GO:0001776 | 79 | 0.028 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.027 | |
| receptor mediated endocytosis | GO:0006898 | 51 | 0.027 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.027 | |
| gene silencing by rna | GO:0031047 | 19 | 0.027 | |
| dna packaging | GO:0006323 | 30 | 0.027 | |
| regulation of dna damage checkpoint | GO:2000001 | 3 | 0.027 | |
| response to alcohol | GO:0097305 | 48 | 0.027 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.026 | |
| response to iron ion | GO:0010039 | 4 | 0.026 | |
| protein targeting | GO:0006605 | 143 | 0.026 | |
| body morphogenesis | GO:0010171 | 45 | 0.025 | |
| rna catabolic process | GO:0006401 | 29 | 0.025 | |
| dna conformation change | GO:0071103 | 37 | 0.025 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.024 | Fly |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.024 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.024 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.024 | |
| deoxyribose phosphate metabolic process | GO:0019692 | 9 | 0.024 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.023 | |
| cellular glucose homeostasis | GO:0001678 | 52 | 0.023 | |
| camera type eye development | GO:0043010 | 266 | 0.023 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.023 | |
| transcription coupled nucleotide excision repair | GO:0006283 | 2 | 0.023 | |
| positive regulation of gtp catabolic process | GO:0033126 | 85 | 0.022 | |
| amine metabolic process | GO:0009308 | 45 | 0.022 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.022 | |
| mrna splicing via spliceosome | GO:0000398 | 43 | 0.022 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.022 | |
| insulin secretion | GO:0030073 | 89 | 0.022 | |
| regulation of exit from mitosis | GO:0007096 | 1 | 0.022 | |
| neural tube closure | GO:0001843 | 90 | 0.021 | |
| neuron migration | GO:0001764 | 122 | 0.021 | |
| endocytosis | GO:0006897 | 168 | 0.021 | |
| gland development | GO:0048732 | 330 | 0.021 | |
| regulation of protein transport | GO:0051223 | 163 | 0.021 | |
| mitotic centrosome separation | GO:0007100 | 4 | 0.021 | |
| organ growth | GO:0035265 | 117 | 0.021 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.020 | Worm |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.020 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.020 | |
| asymmetric stem cell division | GO:0098722 | 3 | 0.020 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.020 | |
| circulatory system process | GO:0003013 | 197 | 0.020 | |
| oocyte differentiation | GO:0009994 | 35 | 0.020 | |
| regulation of embryonic development | GO:0045995 | 71 | 0.020 | Worm |
| neural precursor cell proliferation | GO:0061351 | 121 | 0.020 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.020 | |
| synaptonemal complex assembly | GO:0007130 | 13 | 0.020 | |
| negative regulation of purine nucleotide catabolic process | GO:0033122 | 9 | 0.020 | |
| dephosphorylation | GO:0016311 | 129 | 0.020 | |
| spermatogenesis | GO:0007283 | 284 | 0.020 | |
| protein localization to organelle | GO:0033365 | 185 | 0.019 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.019 | |
| negative regulation of cytoskeleton organization | GO:0051494 | 36 | 0.019 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.019 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.019 | |
| cytokinesis | GO:0000910 | 17 | 0.019 | |
| developmental maturation | GO:0021700 | 193 | 0.019 | |
| nuclear import | GO:0051170 | 95 | 0.019 | |
| neural tube development | GO:0021915 | 160 | 0.019 | |
| protein maturation | GO:0051604 | 176 | 0.018 | |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.018 | |
| regulation of rho gtpase activity | GO:0032319 | 58 | 0.018 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.018 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.018 | |
| female gamete generation | GO:0007292 | 74 | 0.018 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.018 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.018 | |
| response to inorganic substance | GO:0010035 | 96 | 0.018 | |
| cellular homeostasis | GO:0019725 | 240 | 0.018 | |
| negative regulation of atpase activity | GO:0032780 | 2 | 0.017 | |
| protein import into nucleus | GO:0006606 | 95 | 0.017 | |
| histone acetylation | GO:0016573 | 41 | 0.017 | |
| positive regulation of intracellular protein transport | GO:0090316 | 42 | 0.017 | |
| dendrite development | GO:0016358 | 115 | 0.017 | |
| single organism nuclear import | GO:1902593 | 95 | 0.017 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.017 | |
| amide transport | GO:0042886 | 138 | 0.016 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.016 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.016 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.016 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.016 | |
| blood circulation | GO:0008015 | 195 | 0.016 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.016 | |
| viral life cycle | GO:0019058 | 36 | 0.016 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.016 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.016 | |
| peptide transport | GO:0015833 | 133 | 0.016 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.016 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.015 | |
| regulation of cytokinesis | GO:0032465 | 5 | 0.015 | |
| g2 m transition of mitotic cell cycle | GO:0000086 | 20 | 0.015 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.015 | |
| rna splicing | GO:0008380 | 54 | 0.015 | |
| positive regulation of cell division | GO:0051781 | 31 | 0.015 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.015 | |
| protein homooligomerization | GO:0051260 | 43 | 0.015 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.015 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.015 | |
| positive regulation of fibroblast proliferation | GO:0048146 | 20 | 0.015 | |
| organelle localization | GO:0051640 | 179 | 0.015 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.015 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.015 | Mouse Fly |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.015 | |
| cell cycle g2 m phase transition | GO:0044839 | 20 | 0.014 | |
| negative regulation of nucleoside metabolic process | GO:0045978 | 11 | 0.014 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.014 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.014 | |
| regulation of cardiac muscle cell proliferation | GO:0060043 | 23 | 0.014 | |
| cardiac muscle tissue growth | GO:0055017 | 37 | 0.014 | |
| oxidation reduction process | GO:0055114 | 342 | 0.014 | |
| rna localization | GO:0006403 | 23 | 0.014 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.014 | |
| spindle assembly involved in female meiosis | GO:0007056 | 3 | 0.014 | Fly |
| regulation of peptide transport | GO:0090087 | 91 | 0.014 | |
| fertilization | GO:0009566 | 127 | 0.014 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 88 | 0.014 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.014 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.014 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.014 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.013 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.013 | |
| cation transport | GO:0006812 | 399 | 0.013 | |
| striated muscle cell proliferation | GO:0014855 | 39 | 0.013 | |
| dna ligation | GO:0006266 | 3 | 0.013 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.013 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.013 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.013 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.013 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.013 | |
| membrane organization | GO:0061024 | 245 | 0.013 | |
| cardiac muscle cell differentiation | GO:0055007 | 69 | 0.013 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.013 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.013 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.013 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.013 | |
| spindle assembly involved in meiosis | GO:0090306 | 4 | 0.013 | Fly |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 2 | 0.013 | |
| response to activity | GO:0014823 | 13 | 0.013 | |
| negative regulation of wnt signaling pathway | GO:0030178 | 73 | 0.013 | |
| response to oxygen levels | GO:0070482 | 62 | 0.013 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.013 | |
| regulation of organ growth | GO:0046620 | 61 | 0.013 | |
| muscle tissue development | GO:0060537 | 308 | 0.013 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 88 | 0.013 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.013 | Worm |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.013 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.012 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.012 | |
| negative regulation of cellular catabolic process | GO:0031330 | 47 | 0.012 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.012 | |
| phagocytosis | GO:0006909 | 66 | 0.012 | |
| oogenesis | GO:0048477 | 56 | 0.012 | |
| regulation of carbohydrate metabolic process | GO:0006109 | 75 | 0.012 | |
| monosaccharide metabolic process | GO:0005996 | 106 | 0.012 | |
| skin development | GO:0043588 | 220 | 0.012 | |
| establishment of rna localization | GO:0051236 | 18 | 0.012 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.012 | |
| positive regulation of map kinase activity | GO:0043406 | 84 | 0.012 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.012 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.012 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.012 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.012 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.012 | |
| cell maturation | GO:0048469 | 127 | 0.012 | |
| heart process | GO:0003015 | 94 | 0.012 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.011 | |
| oocyte maturation | GO:0001556 | 18 | 0.011 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.011 | |
| protein complex localization | GO:0031503 | 19 | 0.011 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.011 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.011 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.011 | |
| digestive system development | GO:0055123 | 200 | 0.011 | |
| cellular protein complex disassembly | GO:0043624 | 36 | 0.011 | |
| cell chemotaxis | GO:0060326 | 81 | 0.011 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.011 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.011 | |
| regulation of cell division | GO:0051302 | 76 | 0.011 | |
| regulation of mrna processing | GO:0050684 | 41 | 0.011 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.011 | |
| cellular response to organic cyclic compound | GO:0071407 | 87 | 0.011 | |
| anion transport | GO:0006820 | 177 | 0.011 | |
| regulation of dna dependent dna replication initiation | GO:0030174 | 3 | 0.011 | |
| neural tube formation | GO:0001841 | 108 | 0.011 | |
| chromosome segregation | GO:0007059 | 48 | 0.011 | |
| chemotaxis | GO:0006935 | 247 | 0.011 | |
| negative regulation of lymphocyte differentiation | GO:0045620 | 32 | 0.010 | |
| gtp metabolic process | GO:0046039 | 144 | 0.010 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.010 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.010 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.010 | |
| microtubule depolymerization | GO:0007019 | 15 | 0.010 | |
| posttranscriptional gene silencing by rna | GO:0035194 | 10 | 0.010 | |
| regulation of transcription factor import into nucleus | GO:0042990 | 24 | 0.010 | |
| cellular response to hexose stimulus | GO:0071331 | 47 | 0.010 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.010 | |
| male gonad development | GO:0008584 | 88 | 0.010 | |
| wound healing | GO:0042060 | 157 | 0.010 | |
| regulation of reproductive process | GO:2000241 | 66 | 0.010 | |
| double strand break repair via homologous recombination | GO:0000724 | 21 | 0.010 | |
| regulation of cell activation | GO:0050865 | 289 | 0.010 | |
| double strand break repair via nonhomologous end joining | GO:0006303 | 10 | 0.010 | |
