Mus musculus

33 known processes

Col1a2

collagen, type I, alpha 2

(Aliases: Cola-2,oim,AA960264,Cola2,AI325291,Col1a-2)

Col1a2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
extracellular structure organizationGO:00430621480.997
Human Mouse
extracellular matrix organizationGO:00301981470.994
Human Mouse
cellular response to amino acid stimulusGO:0071230290.994
proteoglycan metabolic processGO:0006029380.941
Mouse
response to amino acidGO:0043200370.917
chondrocyte differentiationGO:0002062720.910
Mouse
skeletal system developmentGO:00015013560.901
Human Mouse
ossificationGO:00015032160.888
Mouse
protein heterotrimerizationGO:007020880.873
connective tissue developmentGO:00614481790.811
Mouse
endochondral bone morphogenesisGO:0060350500.810
Mouse
bone developmentGO:00603481200.804
Mouse
fibril organizationGO:009743520.802
positive regulation of cell substrate adhesionGO:0010811470.782
cartilage development involved in endochondral bone morphogenesisGO:0060351240.752
Mouse
cellular response to acid chemicalGO:0071229680.733
replacement ossificationGO:0036075260.725
Mouse
bone trabecula formationGO:006034690.718
Mouse
response to organonitrogen compoundGO:00102432460.662
aorta morphogenesisGO:0035909220.632
Mouse
extrinsic apoptotic signaling pathwayGO:00971911260.629
Mouse
sensory organ morphogenesisGO:00905962420.625
Mouse
cellular response to growth factor stimulusGO:00713631970.623
Human Mouse
extracellular fibril organizationGO:004320620.621
cellular response to organonitrogen compoundGO:00714171450.616
protein trimerizationGO:0070206130.595
muscle tissue developmentGO:00605373080.583
Mouse
collagen fibril organizationGO:0030199320.533
Human Mouse
cellular response to transforming growth factor beta stimulusGO:0071560880.514
Human
embryonic skeletal system developmentGO:00487061200.514
Mouse
regulation of cell substrate adhesionGO:0010810730.503
Mouse
cell matrix adhesionGO:0007160680.501
Mouse
head morphogenesisGO:0060323340.496
Mouse
negative regulation of tooth mineralizationGO:007017110.478
regulation of apoptotic signaling pathwayGO:20012331970.476
Mouse
response to growth factorGO:00708481980.455
Human Mouse
skeletal system morphogenesisGO:00487052030.454
Mouse
cerebral cortex developmentGO:0021987860.453
Mouse
negative regulation of apoptotic signaling pathwayGO:20012341040.448
Mouse
cellular response to bmp stimulusGO:0071773140.441
Mouse
response to oxidative stressGO:00069791230.430
trabecula formationGO:0060343240.416
Mouse
lung developmentGO:00303241640.409
anatomical structure homeostasisGO:00602491450.404
Mouse
response to bmpGO:0071772140.401
Mouse
negative regulation of neuron migrationGO:200122360.396
Mouse
cardiac chamber morphogenesisGO:0003206930.392
Mouse
cartilage developmentGO:00512161400.391
Mouse
striated muscle tissue developmentGO:00147062930.374
Mouse
negative regulation of cell substrate adhesionGO:0010812160.361
Mouse
embryonic organ morphogenesisGO:00485622760.361
Mouse
smooth muscle tissue developmentGO:0048745220.358
Mouse
palate developmentGO:0060021760.326
Mouse
tendon developmentGO:003598960.326
Mouse
aorta developmentGO:0035904230.321
Mouse
transforming growth factor beta receptor signaling pathwayGO:0007179710.314
Human
rho protein signal transductionGO:0007266320.295
Human Mouse
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.291
Mouse
cartilage condensationGO:0001502180.286
Mouse
aorta smooth muscle tissue morphogenesisGO:006041420.283
Mouse
limb developmentGO:00601731660.280
Mouse
glycoprotein metabolic processGO:00091001160.278
Mouse
regulation of tooth mineralizationGO:007017020.276
cardiac ventricle morphogenesisGO:0003208500.271
Mouse
sensory perception of soundGO:0007605970.258
Mouse
regulation of chondrocyte differentiationGO:0032330330.256
protein heterooligomerizationGO:0051291140.251
face morphogenesisGO:0060325290.247
Mouse
ventricular cardiac muscle tissue morphogenesisGO:0055010320.246
Mouse
regulation of removal of superoxide radicalsGO:200012140.241
response to acid chemicalGO:00011011110.239
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.237
Mouse
bone morphogenesisGO:0060349780.236
Mouse
notochord developmentGO:0030903200.235
Mouse
regulation of biomineral tissue developmentGO:0070167330.226
negative regulation of cell developmentGO:00107211690.221
Mouse
peptide cross linking via chondroitin 4 sulfate glycosaminoglycanGO:001980080.211
biomineral tissue developmentGO:0031214640.202
wound healingGO:00420601570.202
cell substrate adhesionGO:00315891300.201
Mouse
response to transforming growth factor betaGO:0071559880.195
Human
elastic fiber assemblyGO:004825140.194
endoderm formationGO:0001706200.192
trabecula morphogenesisGO:0061383400.191
Mouse
retinal blood vessel morphogenesisGO:006130430.190
negative regulation of gastrulationGO:200054230.189
response to inorganic substanceGO:0010035960.187
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.187
Mouse
blood vessel morphogenesisGO:00485142850.187
Mouse
limb bud formationGO:0060174100.182
Mouse
muscle tissue morphogenesisGO:0060415530.179
Mouse
positive regulation of rho protein signal transductionGO:003502570.174
Mouse
ear developmentGO:00435832000.173
Mouse
regulation of cell migrationGO:00303342190.172
Mouse
regulation of cell adhesionGO:00301551540.170
Mouse
cardiac muscle tissue morphogenesisGO:0055008440.162
Mouse
sensory perception of mechanical stimulusGO:00509541070.156
Mouse
face developmentGO:0060324380.155
Mouse
respiratory tube developmentGO:00303231670.155
peripheral nervous system axon regenerationGO:001401220.149
artery developmentGO:0060840530.145
Mouse
ear morphogenesisGO:00424711180.145
Mouse
signal transduction in absence of ligandGO:0038034550.141
Mouse
tissue homeostasisGO:00018941150.141
Mouse
positive regulation of ras protein signal transductionGO:0046579130.130
Mouse
cell adhesionGO:00071553290.126
Mouse
multicellular organismal homeostasisGO:00488711640.124
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.123
Human
inner ear morphogenesisGO:00424721010.123
Mouse
ras protein signal transductionGO:0007265770.122
Human Mouse
regulation of ceramide biosynthetic processGO:200030310.121
growth plate cartilage developmentGO:0003417140.119
negative regulation of cell adhesionGO:0007162450.118
Mouse
regulation of proteolysisGO:00301621640.118
negative regulation of ossificationGO:0030279490.115
response to organic cyclic compoundGO:00140701980.114
Rat
direct ossificationGO:003607250.111
Mouse
cellular response to abiotic stimulusGO:0071214560.110
Mouse
neuron migrationGO:00017641220.105
Mouse
digestive tract morphogenesisGO:00485461470.104
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.104
ventricular cardiac muscle tissue developmentGO:0003229380.103
Mouse
protein oligomerizationGO:0051259670.101
appendage morphogenesisGO:00351071490.100
Mouse
digestive system developmentGO:00551232000.099
Mouse
negative regulation of signal transduction in absence of ligandGO:1901099160.099
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.098
negative regulation of cell proliferationGO:00082852960.095
bone trabecula morphogenesisGO:0061430120.094
Mouse
embryonic skeletal system morphogenesisGO:0048704910.092
Mouse
protein hydroxylationGO:001812640.092
digestive tract developmentGO:00485651900.091
Mouse
respiratory system developmentGO:00605411900.090
endothelial cell apoptotic processGO:007257790.087
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.084
negative regulation of blood vessel morphogenesisGO:2000181250.082
otic vesicle developmentGO:0071599140.077
Mouse
physiological cardiac muscle hypertrophyGO:000330130.076
regulation of ossificationGO:00302781120.074
negative regulation of macrophage chemotaxisGO:001076010.074
negative regulation of cell migrationGO:0030336590.073
Mouse
heart morphogenesisGO:00030071780.073
Mouse
chondroitin sulfate metabolic processGO:0030204170.071
cellular response to superoxideGO:0071451140.071
regulation of cell motilityGO:20001452360.070
Mouse
nephron developmentGO:00720061090.068
cardiac chamber developmentGO:00032051080.067
Mouse
collagen metabolic processGO:0032963170.064
multicellular organismal catabolic processGO:004424370.064
cellular response to mechanical stimulusGO:007126070.063
Mouse
regulation of endodermal cell differentiationGO:190322420.062
response to oxygen radicalGO:0000305160.062
regulation of transmission of nerve impulseGO:005196910.062
regulation of neuron migrationGO:2001222220.062
Mouse
spermatogenesisGO:00072832840.062
regulation of angiogenesisGO:0045765810.062
positive regulation of nervous system developmentGO:00519622210.061
regulation of toll signaling pathwayGO:000859210.060
antibacterial peptide secretionGO:000277910.059
negative regulation of cellular response to growth factor stimulusGO:0090288460.058
small gtpase mediated signal transductionGO:0007264970.057
Human Mouse
formation of primary germ layerGO:0001704770.056
pallium developmentGO:00215431200.055
Mouse
negative regulation of intracellular signal transductionGO:19025321670.055
regulation of peptidase activityGO:0052547960.055
skeletal muscle satellite cell maintenance involved in skeletal muscle regenerationGO:001483430.053
regulation of cartilage developmentGO:0061035440.052
antimicrobial peptide secretionGO:000277610.052
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.051
Mouse
cardiac muscle tissue developmentGO:00487381300.049
Mouse
forebrain developmentGO:00309003020.049
Mouse
protein maturationGO:00516041760.049
endoderm developmentGO:0007492450.048
sensory perceptionGO:00076002450.047
Mouse
glycosaminoglycan metabolic processGO:0030203340.047
negative regulation of biomineral tissue developmentGO:0070168110.046
chondroitin sulfate proteoglycan metabolic processGO:0050654200.046
negative regulation of embryonic developmentGO:0045992220.046
positive regulation of cell developmentGO:00107202370.046
astrocyte fate commitmentGO:006001840.045
acylglycerol metabolic processGO:0006639550.045
chondrocyte developmentGO:0002063240.044
Mouse
negative regulation of epithelial cell proliferationGO:0050680640.044
neuromuscular process controlling balanceGO:0050885590.044
cardiac ventricle developmentGO:0003231830.044
Mouse
cell growth involved in cardiac muscle cell developmentGO:006104930.043
positive regulation of hydrolase activityGO:00513451480.043
sequestering of bmp in extracellular matrixGO:003558230.042
regulation of cellular response to oxidative stressGO:1900407190.042
peptide cross linkingGO:0018149100.040
positive regulation of metanephric mesenchymal cell migrationGO:200059110.040
limb morphogenesisGO:00351081490.040
Mouse
protein processingGO:00164851630.038
metal ion homeostasisGO:00550651890.038
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.038
endodermal cell differentiationGO:0035987140.038
response to monosaccharideGO:0034284670.038
mucopolysaccharide metabolic processGO:1903510250.038
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.037
renal system developmentGO:00720012250.036
type b pancreatic cell proliferationGO:0044342100.036
aminoglycan metabolic processGO:0006022340.035
regulation of cell growth involved in cardiac muscle cell developmentGO:006105030.035
negative regulation of phospholipase activityGO:001051940.035
positive regulation of bone remodelingGO:0046852130.035
response to hyperoxiaGO:005509320.034
regulation of hydrolase activityGO:00513362460.034
eye photoreceptor cell differentiationGO:0001754410.031
regulation of cellular response to stressGO:00801351590.030
neuromuscular processGO:0050905990.030
negative regulation of angiogenesisGO:0016525250.030
sequestering of extracellular ligand from receptorGO:003558160.030
negative regulation of endodermal cell differentiationGO:190322510.030
negative regulation of nervous system developmentGO:00519611560.029
Mouse
removal of superoxide radicalsGO:0019430120.029
oxidation reduction processGO:00551143420.029
regulation of schwann cell proliferationGO:001062420.029
multicellular organismal metabolic processGO:0044236280.028
regulation of hormone levelsGO:00108172110.026
innate immune responseGO:00450871570.026
negative regulation of odontogenesisGO:004248330.026
organ growthGO:00352651170.026
regulation of cellular ketone metabolic processGO:0010565660.026
bone mineralizationGO:0030282540.025
urogenital system developmentGO:00016552610.025
camera type eye developmentGO:00430102660.025
regulation of ras protein signal transductionGO:00465781140.025
Mouse
single organism cell adhesionGO:00986021560.025
regulation of epithelial cell proliferationGO:00506781410.025
positive regulation of cell projection organizationGO:0031346950.025
appendage developmentGO:00487361660.025
Mouse
response to metal ionGO:0010038470.025
collagen biosynthetic processGO:003296470.024
monocarboxylic acid metabolic processGO:00327871910.024
bone resorptionGO:0045453380.024
positive regulation of neuron differentiationGO:00456661410.024
regulation of system processGO:00440572000.024
response to extracellular stimulusGO:00099911270.023
negative regulation of cartilage developmentGO:0061037170.023
peptide metabolic processGO:0006518460.023
response to steroid hormoneGO:0048545560.023
regulation of cellular response to growth factor stimulusGO:0090287820.023
regulation of body fluid levelsGO:00508781620.023
monosaccharide transportGO:0015749580.023
response to radiationGO:00093141650.023
cellular response to oxygen radicalGO:0071450140.023
negative regulation of immune system processGO:00026832090.023
gastrulationGO:00073691160.023
sulfur compound metabolic processGO:00067901000.023
fat cell differentiationGO:00454441600.022
positive regulation of cell growthGO:0030307330.022
cardiac cell developmentGO:0055006410.022
angiogenesisGO:00015252010.022
regulation of bone mineralizationGO:0030500310.022
microtubule based processGO:00070172360.022
regulation of cardiac muscle tissue growthGO:0055021260.022
negative regulation of cell motilityGO:2000146610.021
Mouse
carbohydrate homeostasisGO:00335001280.021
skeletal muscle organ developmentGO:00605381630.021
regulation of neuron projection developmentGO:00109751690.021
multicellular organismal macromolecule metabolic processGO:0044259190.021
negative regulation of molecular functionGO:00440922580.021
positive regulation of insulin secretionGO:0032024260.020
telencephalon developmentGO:00215371860.020
Mouse
regulation of cellular component biogenesisGO:00440871810.019
cell type specific apoptotic processGO:00972852680.018
regionalizationGO:00030023370.018
odontogenesisGO:0042476780.018
positive regulation of neuron projection developmentGO:0010976790.018
insulin processingGO:003007020.018
regulation of translationGO:0006417710.018
cardiac muscle cell developmentGO:0055013390.018
neural precursor cell proliferationGO:00613511210.018
organelle fissionGO:00482851700.017
oviduct developmentGO:006006630.017
pancreatic pp cell fate commitmentGO:000332920.017
regulation of map kinase activityGO:00434051200.017
peptidyl amino acid modificationGO:00181933360.017
negative regulation of hydrolase activityGO:0051346710.017
epidermis developmentGO:00085441870.017
regulation of synaptic growth at neuromuscular junctionGO:000858240.017
epithelial to mesenchymal transitionGO:0001837470.017
response to reactive oxygen speciesGO:0000302560.017
synaptic transmissionGO:00072683290.017
macromolecule catabolic processGO:00090572810.016
negative regulation of lipoprotein lipase activityGO:005100510.016
antimicrobial peptide biosynthetic processGO:000277720.016
regulation of rho protein signal transductionGO:0035023710.016
Mouse
positive regulation of bone resorptionGO:0045780130.016
cellular modified amino acid metabolic processGO:0006575630.016
molting cycleGO:0042303900.016
physiological muscle hypertrophyGO:000329830.015
apoptotic signaling pathwayGO:00971903060.015
Mouse
cellular response to cytokine stimulusGO:00713451890.015
negative regulation of vasculature developmentGO:1901343260.015
prostate gland stromal morphogenesisGO:006074120.015
response to peptideGO:19016521360.015
positive regulation of cell deathGO:00109422240.014
positive regulation of semaphorin plexin signaling pathwayGO:200126210.014
reactive oxygen species metabolic processGO:0072593840.014
stem cell differentiationGO:00488632680.014
regulation of sphingolipid biosynthetic processGO:009015310.014
long term synaptic potentiationGO:0060291250.014
female gonad developmentGO:0008585710.014
regulation of anatomical structure sizeGO:00900661780.014
intestinal epithelial structure maintenanceGO:006072940.014
early endosome to late endosome transportGO:004502220.014
cell recognitionGO:0008037830.014
positive regulation of response to woundingGO:1903036660.014
response to nitric oxideGO:007173140.014
peptidyl serine modificationGO:0018209830.014
negative regulation of cell proliferation involved in contact inhibitionGO:006024430.014
positive regulation of peptidase activityGO:0010952490.014
peptide secretionGO:00027901140.014
developmental maturationGO:00217001930.014
development of primary female sexual characteristicsGO:0046545730.014
cell growthGO:00160491300.014
hormone secretionGO:00468791280.013
cardiac muscle cell differentiationGO:0055007690.013
cardiocyte differentiationGO:0035051870.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
cellular response to organic cyclic compoundGO:0071407870.013
cellular response to vitaminGO:007129520.013
covalent chromatin modificationGO:00165691630.013
negative regulation of protein activation cascadeGO:200025830.013
positive regulation of proteolysisGO:0045862850.013
antibacterial peptide biosynthetic processGO:000278020.013
superoxide metabolic processGO:0006801270.013
tissue remodelingGO:00487711020.012
kidney developmentGO:00018222130.012
cellular response to fluid shear stressGO:007149840.012
response to epidermal growth factorGO:007084940.012
protein localization to nucleusGO:00345041210.012
response to molecule of bacterial originGO:00022371430.012
regulation of cell sizeGO:0008361720.012
regulation of homeostatic processGO:00328441820.012
peripheral nervous system neuron axonogenesisGO:004893630.012
cellular response to oxidative stressGO:0034599760.012
humoral immune responseGO:0006959570.012
integrin biosynthetic processGO:004511210.012
basement membrane organizationGO:007171180.011
negative regulation of growthGO:0045926990.011
organonitrogen compound biosynthetic processGO:19015661920.011
epithelial cell proliferationGO:00506731740.011
female sex differentiationGO:0046660840.011
cellular ketone metabolic processGO:0042180840.011
response to superoxideGO:0000303160.011
integrin mediated signaling pathwayGO:0007229270.011
response to endoplasmic reticulum stressGO:0034976530.011
regulation of response to reactive oxygen speciesGO:190103190.011
regulation of wnt signaling pathwayGO:00301111230.011
macrophage chemotaxisGO:0048246140.011
negative regulation of fat cell differentiationGO:0045599360.011
cardiac septum morphogenesisGO:0060411460.011
regulation of gastrulationGO:0010470160.011
notochord cell differentiationGO:006003410.011
negative regulation of dna replicationGO:000815640.011
transforming growth factor beta2 productionGO:003290620.011
bmp signaling pathwayGO:0030509930.011
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathwayGO:003579310.011
phagolysosome assemblyGO:000184530.011
development of primary sexual characteristicsGO:00451371430.011
negative regulation of protein maturationGO:1903318790.011
skeletal myofibril assemblyGO:001486640.010
transmembrane transportGO:00550854120.010
regulation of vasculogenesisGO:200121290.010
antimicrobial peptide productionGO:000277520.010
regulation of macrophage migration inhibitory factor signaling pathwayGO:200044610.010
response to decreased oxygen levelsGO:0036293590.010
regulation of tissue remodelingGO:0034103380.010
antibacterial humoral responseGO:001973180.010

Col1a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.993
Human
disease of anatomical entityDOID:700.993
Human
muscular diseaseDOID:008000000.969
myopathyDOID:42300.969
muscle tissue diseaseDOID:6600.969
connective tissue diseaseDOID:6500.931
Human
collagen diseaseDOID:85400.721
congenital muscular dystrophyDOID:005055700.674
muscular dystrophyDOID:988400.674
ehlers danlos syndromeDOID:1335900.534
osteochondrodysplasiaDOID:225600.157
Human
bone diseaseDOID:008000100.157
Human
bone development diseaseDOID:008000600.157
Human
osteogenesis imperfectaDOID:1234700.157
Human
heart diseaseDOID:11400.061
cardiomyopathyDOID:005070000.061
cardiovascular system diseaseDOID:128700.061
nervous system diseaseDOID:86300.036
glaucomaDOID:168600.036
retinal diseaseDOID:567900.036
retinal degenerationDOID:846600.036
sensory system diseaseDOID:005015500.036
eye and adnexa diseaseDOID:149200.036
eye diseaseDOID:561400.036
osteoporosisDOID:1147600.020
Human
bone resorption diseaseDOID:008001100.020
Human
bone remodeling diseaseDOID:008000500.020
Human
intrinsic cardiomyopathyDOID:006003600.018