| response to topologically incorrect protein | GO:0035966 | 25 | 0.975 | |
| cellular response to topologically incorrect protein | GO:0035967 | 25 | 0.962 | |
| er nucleus signaling pathway | GO:0006984 | 27 | 0.738 | |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 19 | 0.717 | |
| response to unfolded protein | GO:0006986 | 21 | 0.541 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.509 | |
| protein catabolic process | GO:0030163 | 221 | 0.412 | |
| cellular response to interleukin 4 | GO:0071353 | 21 | 0.401 | |
| glycoprotein biosynthetic process | GO:0009101 | 89 | 0.395 | |
| protein targeting to er | GO:0045047 | 2 | 0.331 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.239 | |
| vascular process in circulatory system | GO:0003018 | 62 | 0.236 | |
| peptidyl asparagine modification | GO:0018196 | 1 | 0.214 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.191 | |
| response to yeast | GO:0001878 | 6 | 0.169 | |
| glycoprotein metabolic process | GO:0009100 | 116 | 0.161 | |
| protein glycosylation | GO:0006486 | 55 | 0.140 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.114 | |
| negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090101 | 61 | 0.103 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.099 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.094 | |
| fertilization | GO:0009566 | 127 | 0.084 | |
| amine metabolic process | GO:0009308 | 45 | 0.081 | |
| protein targeting to membrane | GO:0006612 | 20 | 0.078 | |
| positive regulation of interleukin 6 secretion | GO:2000778 | 1 | 0.077 | |
| negative regulation of transforming growth factor beta receptor signaling pathway | GO:0030512 | 26 | 0.076 | |
| cellular response to toxic substance | GO:0097237 | 7 | 0.073 | |
| substantia nigra development | GO:0021762 | 2 | 0.070 | |
| t cell differentiation | GO:0030217 | 174 | 0.070 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.070 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.068 | |
| chaperone mediated protein folding | GO:0061077 | 10 | 0.067 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.063 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 10 | 0.061 | |
| protein n linked glycosylation | GO:0006487 | 12 | 0.057 | |
| body morphogenesis | GO:0010171 | 45 | 0.057 | |
| protein localization to organelle | GO:0033365 | 185 | 0.056 | |
| response to organophosphorus | GO:0046683 | 22 | 0.055 | |
| cellular response to extracellular stimulus | GO:0031668 | 81 | 0.055 | |
| protein n linked glycosylation via asparagine | GO:0018279 | 1 | 0.053 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.051 | |
| response to antibiotic | GO:0046677 | 11 | 0.050 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.049 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.049 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.049 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.049 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.048 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.047 | |
| response to endoplasmic reticulum stress | GO:0034976 | 53 | 0.047 | |
| regulation of tube size | GO:0035150 | 57 | 0.046 | |
| regulation of mrna metabolic process | GO:1903311 | 43 | 0.044 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.043 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.042 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.042 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.042 | |
| t cell activation | GO:0042110 | 289 | 0.041 | |
| dopaminergic neuron differentiation | GO:0071542 | 14 | 0.041 | |
| regulation of systemic arterial blood pressure | GO:0003073 | 61 | 0.040 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.039 | |
| poly a mrna export from nucleus | GO:0016973 | 4 | 0.038 | |
| transmembrane transport | GO:0055085 | 412 | 0.037 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.037 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.037 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.037 | |
| nuclear division | GO:0000280 | 158 | 0.036 | |
| cotranslational protein targeting to membrane | GO:0006613 | 2 | 0.036 | |
| establishment of protein localization to membrane | GO:0090150 | 54 | 0.035 | |
| regulation of rna splicing | GO:0043484 | 37 | 0.035 | |
| cell recognition | GO:0008037 | 83 | 0.034 | |
| muscle tissue development | GO:0060537 | 308 | 0.034 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.034 | |
| lipid localization | GO:0010876 | 126 | 0.034 | |
| maintenance of protein localization in organelle | GO:0072595 | 2 | 0.034 | |
| glycosylation | GO:0070085 | 62 | 0.033 | |
| male genitalia morphogenesis | GO:0048808 | 4 | 0.033 | |
| pore complex assembly | GO:0046931 | 3 | 0.033 | |
| establishment of protein localization to endoplasmic reticulum | GO:0072599 | 2 | 0.033 | |
| protein folding | GO:0006457 | 28 | 0.032 | |
| negative regulation of cellular response to growth factor stimulus | GO:0090288 | 46 | 0.031 | |
| circulatory system process | GO:0003013 | 197 | 0.031 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.030 | |
| positive regulation of systemic arterial blood pressure | GO:0003084 | 9 | 0.030 | |
| macromolecule glycosylation | GO:0043413 | 55 | 0.029 | |
| response to testosterone | GO:0033574 | 3 | 0.028 | |
| posttranslational protein targeting to membrane | GO:0006620 | 2 | 0.028 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.028 | |
| positive regulation of blood pressure | GO:0045777 | 21 | 0.028 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.028 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.028 | |
| regulation of phosphoprotein phosphatase activity | GO:0043666 | 3 | 0.028 | |
| positive regulation of cell adhesion | GO:0045785 | 80 | 0.027 | |
| regulation of mrna processing | GO:0050684 | 41 | 0.027 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.027 | |
| protein ubiquitination | GO:0016567 | 171 | 0.026 | |
| positive regulation of cardiac muscle contraction | GO:0060452 | 2 | 0.026 | |
| gland development | GO:0048732 | 330 | 0.026 | |
| renal system development | GO:0072001 | 225 | 0.026 | |
| response to growth factor | GO:0070848 | 198 | 0.025 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.025 | |
| interleukin 6 production | GO:0032635 | 58 | 0.025 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.024 | |
| midgut development | GO:0007494 | 4 | 0.024 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.024 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.024 | |
| translation | GO:0006412 | 93 | 0.024 | |
| protein transmembrane transport | GO:0071806 | 8 | 0.023 | |
| positive regulation of cell motility | GO:2000147 | 116 | 0.023 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.022 | |
| mrna splicing via spliceosome | GO:0000398 | 43 | 0.022 | |
| lipid biosynthetic process | GO:0008610 | 179 | 0.022 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.022 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.022 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.022 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.022 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.022 | |
| regulation of translation | GO:0006417 | 71 | 0.022 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.021 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.021 | |
| ear development | GO:0043583 | 200 | 0.021 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.021 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.021 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.021 | |
| kidney development | GO:0001822 | 213 | 0.021 | |
| regulation of phosphatase activity | GO:0010921 | 12 | 0.021 | |
| positive regulation of growth hormone secretion | GO:0060124 | 3 | 0.021 | |
| nuclear transport | GO:0051169 | 139 | 0.021 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.021 | |
| regulation of organ morphogenesis | GO:2000027 | 144 | 0.020 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.020 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.020 | |
| cellular response to glucose starvation | GO:0042149 | 5 | 0.020 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.020 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 4 | 0.020 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.020 | |
| response to interleukin 4 | GO:0070670 | 23 | 0.020 | |
| maintenance of location | GO:0051235 | 89 | 0.020 | |
| cellular response to antibiotic | GO:0071236 | 4 | 0.020 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.020 | |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 34 | 0.019 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.019 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.019 | |
| response to purine containing compound | GO:0014074 | 28 | 0.019 | |
| lateral inhibition | GO:0046331 | 1 | 0.019 | |
| mrna metabolic process | GO:0016071 | 84 | 0.019 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.019 | |
| blood circulation | GO:0008015 | 195 | 0.019 | |
| neurological system process involved in regulation of systemic arterial blood pressure | GO:0001976 | 18 | 0.019 | |
| leukocyte migration | GO:0050900 | 124 | 0.019 | |
| interleukin 6 secretion | GO:0072604 | 3 | 0.019 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.019 | |
| striated muscle cell development | GO:0055002 | 125 | 0.018 | |
| digestive system development | GO:0055123 | 200 | 0.018 | |
| urogenital system development | GO:0001655 | 261 | 0.018 | |
| cerebellum development | GO:0021549 | 77 | 0.018 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 83 | 0.018 | |
| regulation of cell motility | GO:2000145 | 236 | 0.018 | |
| protein targeting | GO:0006605 | 143 | 0.018 | |
| organelle assembly | GO:0070925 | 177 | 0.018 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.018 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.018 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.017 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.017 | |
| cerebellar cortex development | GO:0021695 | 48 | 0.017 | |
| organelle fission | GO:0048285 | 170 | 0.017 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.017 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.017 | |
| cellular response to nutrient levels | GO:0031669 | 64 | 0.017 | |
| lymphocyte activation involved in immune response | GO:0002285 | 93 | 0.017 | |
| gene silencing by mirna | GO:0035195 | 10 | 0.017 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.016 | |
| photoreceptor cell differentiation | GO:0046530 | 52 | 0.016 | |
| spindle assembly involved in mitosis | GO:0090307 | 4 | 0.016 | |
| response to starvation | GO:0042594 | 65 | 0.016 | |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 43 | 0.016 | |
| gpi anchor metabolic process | GO:0006505 | 7 | 0.016 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.016 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.016 | |
| endodermal digestive tract morphogenesis | GO:0061031 | 4 | 0.016 | |
| regulation of blood pressure | GO:0008217 | 93 | 0.016 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.016 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.016 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.016 | |
| membrane organization | GO:0061024 | 245 | 0.016 | |
| hindbrain development | GO:0030902 | 128 | 0.016 | |
| spermatogenesis | GO:0007283 | 284 | 0.016 | |
| regulation of cell migration | GO:0030334 | 219 | 0.015 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.015 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.015 | |
| cytokine production | GO:0001816 | 319 | 0.015 | |
| cation transport | GO:0006812 | 399 | 0.015 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.015 | |
| response to nutrient levels | GO:0031667 | 109 | 0.015 | |
| positive regulation of growth | GO:0045927 | 104 | 0.015 | |
| response to oxygen levels | GO:0070482 | 62 | 0.015 | |
| midbrain development | GO:0030901 | 35 | 0.015 | |
| regulation of blood vessel size | GO:0050880 | 56 | 0.015 | |
| positive regulation of endocytosis | GO:0045807 | 42 | 0.015 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.015 | |
| positive regulation of t cell activation | GO:0050870 | 101 | 0.015 | |
| interspecies interaction between organisms | GO:0044419 | 83 | 0.015 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.015 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.014 | |
| t cell differentiation in thymus | GO:0033077 | 77 | 0.014 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.014 | |
| germ cell development | GO:0007281 | 185 | 0.014 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.014 | |
| response to radiation | GO:0009314 | 165 | 0.014 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.014 | |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.014 | |
| neural nucleus development | GO:0048857 | 22 | 0.014 | |
| single fertilization | GO:0007338 | 82 | 0.014 | |
| regulation of dendritic cell chemotaxis | GO:2000508 | 1 | 0.014 | |
| toxin transport | GO:1901998 | 38 | 0.014 | |
| mrna processing | GO:0006397 | 63 | 0.014 | |
| endocytosis | GO:0006897 | 168 | 0.014 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.014 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.014 | |
| anatomical structure arrangement | GO:0048532 | 20 | 0.014 | |
| protein secretion | GO:0009306 | 111 | 0.014 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.013 | |
| positive regulation of protein secretion | GO:0050714 | 52 | 0.013 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.013 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.013 | |
| vasoconstriction | GO:0042310 | 27 | 0.013 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.013 | |
| immunoglobulin production | GO:0002377 | 73 | 0.013 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.013 | |
| immunoglobulin secretion | GO:0048305 | 17 | 0.013 | |
| dephosphorylation | GO:0016311 | 129 | 0.013 | |
| muscle fiber development | GO:0048747 | 76 | 0.013 | |
| regulation of t cell differentiation | GO:0045580 | 83 | 0.013 | |
| eye photoreceptor cell differentiation | GO:0001754 | 41 | 0.013 | |
| organelle disassembly | GO:1903008 | 2 | 0.013 | |
| connective tissue development | GO:0061448 | 179 | 0.012 | |
| er overload response | GO:0006983 | 6 | 0.012 | |
| sperm egg recognition | GO:0035036 | 37 | 0.012 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.012 | |
| hormone secretion | GO:0046879 | 128 | 0.012 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.012 | |
| glycerophospholipid biosynthetic process | GO:0046474 | 32 | 0.012 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.012 | |
| muscle cell development | GO:0055001 | 133 | 0.012 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.012 | |
| hindbrain morphogenesis | GO:0021575 | 46 | 0.012 | |
| cell activation involved in immune response | GO:0002263 | 126 | 0.012 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.011 | |
| hepaticobiliary system development | GO:0061008 | 67 | 0.011 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.011 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.011 | |
| positive regulation of translation | GO:0045727 | 19 | 0.011 | |
| regulation of cell substrate adhesion | GO:0010810 | 73 | 0.011 | |
| b cell activation | GO:0042113 | 161 | 0.011 | |
| skeletal system development | GO:0001501 | 356 | 0.011 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.011 | |
| peptide transport | GO:0015833 | 133 | 0.011 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.011 | |
| polyamine biosynthetic process | GO:0006596 | 2 | 0.011 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.011 | |
| glucose homeostasis | GO:0042593 | 128 | 0.011 | |
| cell adhesion | GO:0007155 | 329 | 0.011 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.011 | |
| photoreceptor cell development | GO:0042461 | 40 | 0.011 | |
| receptor mediated endocytosis | GO:0006898 | 51 | 0.011 | |
| response to acid chemical | GO:0001101 | 111 | 0.011 | |
| forebrain development | GO:0030900 | 302 | 0.011 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.011 | |
| membrane lipid biosynthetic process | GO:0046467 | 32 | 0.011 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.011 | |
| protein hydroxylation | GO:0018126 | 4 | 0.010 | |
| chemotaxis | GO:0006935 | 247 | 0.010 | |
| protein lipidation | GO:0006497 | 28 | 0.010 | |
| rna processing | GO:0006396 | 105 | 0.010 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.010 | |
| regulation of protein secretion | GO:0050708 | 82 | 0.010 | |
| lipoprotein biosynthetic process | GO:0042158 | 33 | 0.010 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.010 | |
| pharynx development | GO:0060465 | 1 | 0.010 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.010 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.010 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.010 | |
| digestive tract development | GO:0048565 | 190 | 0.010 | |
| male sex differentiation | GO:0046661 | 109 | 0.010 | |
| insulin secretion | GO:0030073 | 89 | 0.010 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.010 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.010 | |
| rna modification | GO:0009451 | 20 | 0.010 | |