Mus musculus

0 known processes

Ctsa

cathepsin A

(Aliases: PPCA,Ppgb,AU019505)

Ctsa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sphingolipid metabolic processGO:0006665450.349
vacuole organizationGO:0007033380.312
proteolysis involved in cellular protein catabolic processGO:00516031470.232
lytic vacuole organizationGO:0080171210.218
ceramide metabolic processGO:0006672310.140
lysosome organizationGO:0007040210.140
membrane lipid biosynthetic processGO:0046467320.135
carbohydrate derivative catabolic processGO:19011362310.112
glycolipid metabolic processGO:0006664250.102
membrane lipid metabolic processGO:0006643530.102
cellular lipid catabolic processGO:0044242520.100
cellular macromolecule catabolic processGO:00442652060.092
maintenance of locationGO:0051235890.090
Worm
skeletal system developmentGO:00015013560.086
angiogenesisGO:00015252010.084
phospholipid transfer to membraneGO:000664920.075
organonitrogen compound catabolic processGO:19015652640.070
sphingolipid catabolic processGO:003014970.068
apoptotic signaling pathwayGO:00971903060.068
cellular lipid metabolic processGO:00442553230.064
glycosphingolipid catabolic processGO:004647950.062
regulation of cellular amino acid metabolic processGO:000652150.062
regulation of peptidase activityGO:0052547960.061
regulation of neuron apoptotic processGO:00435231220.061
vesicle organizationGO:0016050600.060
regulation of membrane potentialGO:00423911920.058
cellular protein catabolic processGO:00442571550.057
oligosaccharide catabolic processGO:000931320.057
lipid catabolic processGO:0016042690.054
neuronal action potentialGO:0019228540.054
wound healingGO:00420601570.053
cell type specific apoptotic processGO:00972852680.052
pigmentationGO:0043473710.051
calcium ion transportGO:00068161590.050
regulation of cellular component biogenesisGO:00440871810.050
amine metabolic processGO:0009308450.050
regulation of hydrolase activityGO:00513362460.050
immune effector processGO:00022523210.050
divalent inorganic cation transportGO:00725111780.049
defense response to other organismGO:00985421970.047
organelle assemblyGO:00709251770.047
oligosaccharide metabolic processGO:0009311110.046
cation homeostasisGO:00550802120.046
multicellular organismal signalingGO:0035637910.045
positive regulation of cellular amino acid metabolic processGO:004576430.043
metal ion homeostasisGO:00550651890.042
transmembrane transportGO:00550854120.042
ceramide biosynthetic processGO:0046513200.041
regulation of cellular ketone metabolic processGO:0010565660.041
purine ribonucleotide catabolic processGO:00091542080.041
male gamete generationGO:00482322850.041
ion transmembrane transportGO:00342203610.040
response to organic cyclic compoundGO:00140701980.040
cellular amino acid metabolic processGO:00065201030.039
regulation of vesicle mediated transportGO:00606271390.039
positive regulation of secretionGO:00510471300.039
protein catabolic processGO:00301632210.038
cellular divalent inorganic cation homeostasisGO:00725031270.038
renal system developmentGO:00720012250.038
regulation of secretionGO:00510462740.038
lateral inhibitionGO:004633110.037
striated muscle tissue developmentGO:00147062930.036
regulation of cellular amine metabolic processGO:0033238200.035
regulation of apoptotic signaling pathwayGO:20012331970.034
positive regulation of cellular amine metabolic processGO:003324050.034
organelle localizationGO:00516401790.034
action potentialGO:0001508780.034
muscle tissue developmentGO:00605373080.033
circulatory system processGO:00030131970.033
inflammatory responseGO:00069542440.032
negative regulation of cellular protein metabolic processGO:00322692470.032
sequestering of metal ionGO:0051238190.032
transmission of nerve impulseGO:0019226760.031
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.031
regulation of anatomical structure sizeGO:00900661780.031
morphogenesis of a branching epitheliumGO:00611381930.031
leukocyte homeostasisGO:0001776790.031
tissue migrationGO:0090130680.031
carbohydrate catabolic processGO:0016052320.031
multi multicellular organism processGO:00447061090.030
reactive oxygen species metabolic processGO:0072593840.030
regulation of protein localizationGO:00328802310.030
cation transmembrane transportGO:00986552660.030
anatomical structure homeostasisGO:00602491450.030
reactive oxygen species biosynthetic processGO:190340980.030
regulation of proteolysisGO:00301621640.030
lysosomal transportGO:0007041100.030
leukocyte mediated immunityGO:00024431740.029
regulation of blood pressureGO:0008217930.029
reactive nitrogen species metabolic processGO:200105700.029
cerebellar granule cell precursor tangential migrationGO:002193510.029
cellular chemical homeostasisGO:00550822150.029
membrane lipid catabolic processGO:004646680.028
cellular amine metabolic processGO:0044106440.028
cation transportGO:00068123990.028
neuron apoptotic processGO:00514021420.028
protein secretionGO:00093061110.028
regulation of cell projection organizationGO:00313442060.027
heterocycle catabolic processGO:00467002800.027
germ cell developmentGO:00072811850.027
positive regulation of secretion by cellGO:19035321140.027
regulation of cellular catabolic processGO:00313292420.027
divalent inorganic cation homeostasisGO:00725071380.027
purine containing compound catabolic processGO:00725232130.027
camera type eye developmentGO:00430102660.027
cellular homeostasisGO:00197252400.027
endomembrane system organizationGO:00102561470.027
anion transportGO:00068201770.026
synapse organizationGO:00508081250.026
endocytosisGO:00068971680.026
lipid localizationGO:00108761260.026
Worm
negative regulation of phosphate metabolic processGO:00459361840.026
t cell activationGO:00421102890.026
regulation of angiotensin metabolic processGO:006017740.025
lipid transportGO:0006869980.025
developmental growth involved in morphogenesisGO:00605601380.025
regulation of cell motilityGO:20001452360.025
regulation of cell migrationGO:00303342190.025
glycerolipid metabolic processGO:00464861220.025
neuron deathGO:00709971540.025
response to organonitrogen compoundGO:00102432460.025
regulation of defense responseGO:00313472330.025
ribonucleotide metabolic processGO:00092592910.025
negative regulation of proteolysisGO:0045861740.024
protein processingGO:00164851630.024
regulation of cell shapeGO:0008360390.024
myelinationGO:0042552740.024
cellular ketone metabolic processGO:0042180840.024
calcium ion homeostasisGO:00550741270.024
glycolipid catabolic processGO:001937750.024
urogenital system developmentGO:00016552610.024
locomotory behaviorGO:00076261950.024
oxidation reduction processGO:00551143420.024
cytokine productionGO:00018163190.024
macroautophagyGO:0016236210.024
negative regulation of phosphorylationGO:00423261660.024
cytoplasmic transportGO:00164822340.023
negative regulation of protein metabolic processGO:00512482820.023
blood vessel morphogenesisGO:00485142850.023
neuromuscular processGO:0050905990.023
leukocyte mediated cytotoxicityGO:0001909620.023
glycosyl compound catabolic processGO:19016582060.023
response to oxidative stressGO:00069791230.022
regulation of transferase activityGO:00513382630.022
membrane fusionGO:0061025380.022
vesicle localizationGO:0051648860.022
purine ribonucleotide metabolic processGO:00091502900.022
innate immune responseGO:00450871570.022
mapk cascadeGO:00001652810.022
nucleoside phosphate metabolic processGO:00067533380.022
peptidyl amino acid modificationGO:00181933360.022
developmental maturationGO:00217001930.021
negative regulation of hydrolase activityGO:0051346710.021
negative regulation of growthGO:0045926990.021
lymphocyte activation involved in immune responseGO:0002285930.021
epithelium migrationGO:0090132630.021
tissue homeostasisGO:00018941150.021
protein maturationGO:00516041760.021
ceramide catabolic processGO:004651470.020
multicellular organismal homeostasisGO:00488711640.020
lymphocyte homeostasisGO:0002260640.020
ameboidal type cell migrationGO:00016671280.020
positive regulation of protein modification processGO:00314012990.020
regulation of hormone levelsGO:00108172110.020
release of sequestered calcium ion into cytosolGO:0051209420.020
g protein coupled receptor signaling pathwayGO:00071862430.020
positive regulation of protein phosphorylationGO:00019342420.020
regulation of secretion by cellGO:19035302490.020
aromatic compound catabolic processGO:00194392860.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
glycosyl compound metabolic processGO:19016572460.020
response to inorganic substanceGO:0010035960.020
liposaccharide metabolic processGO:1903509270.020
regulation of lipid metabolic processGO:00192161180.020
ossificationGO:00015032160.020
skeletal muscle organ developmentGO:00605381630.020
establishment of vesicle localizationGO:0051650810.019
neuromuscular process controlling balanceGO:0050885590.019
regulation of establishment of protein localizationGO:00702011810.019
purine nucleoside metabolic processGO:00422782410.019
regulation of leukocyte mediated immunityGO:00027031040.019
regulation of lymphocyte activationGO:00512492400.019
nucleoside triphosphate metabolic processGO:00091412300.019
lymphocyte mediated immunityGO:00024491390.019
regulation of chemotaxisGO:0050920530.019
response to monosaccharideGO:0034284670.019
regulation of neuron deathGO:19012141340.018
multicellular organismal protein metabolic processGO:004426820.018
negative regulation of cell projection organizationGO:0031345560.018
positive regulation of actin nucleationGO:005112730.018
cellular ion homeostasisGO:00068731650.018
organophosphate catabolic processGO:00464342320.018
negative regulation of nervous system developmentGO:00519611560.018
multicellular organism growthGO:00352641610.018
synaptic vesicle localizationGO:0097479590.018
cellular calcium ion homeostasisGO:00068741190.018
peptide metabolic processGO:0006518460.018
regulation of kinase activityGO:00435492490.018
sequestering of calcium ionGO:0051208180.018
negative regulation of phosphorus metabolic processGO:00105631840.018
negative regulation of cell proliferationGO:00082852960.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.018
heart morphogenesisGO:00030071780.017
positive regulation of cell motilityGO:20001471160.017
neuron projection extensionGO:1990138640.017
positive regulation of cell projection organizationGO:0031346950.017
regulation of calcium ion transportGO:0051924690.017
cell adhesionGO:00071553290.017
adaptive immune responseGO:00022501550.017
divalent metal ion transportGO:00708381720.017
defense response to bacteriumGO:00427421190.017
negative regulation of cellular component organizationGO:00511291940.017
meiotic nuclear divisionGO:00071261150.017
ribonucleotide catabolic processGO:00092612080.017
cell chemotaxisGO:0060326810.017
positive regulation of cell activationGO:00508671580.017
positive regulation of hydrolase activityGO:00513451480.017
positive regulation of mapk cascadeGO:00434101700.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
macromolecule catabolic processGO:00090572810.017
rho protein signal transductionGO:0007266320.017
nucleotide metabolic processGO:00091173320.017
response to extracellular stimulusGO:00099911270.017
positive regulation of t cell activationGO:00508701010.017
regulation of cell activationGO:00508652890.017
axon ensheathmentGO:0008366760.016
positive regulation of lymphocyte activationGO:00512511400.016
membrane protein proteolysisGO:0033619100.016
negative regulation of molecular functionGO:00440922580.016
purine ribonucleoside catabolic processGO:00461302050.016
glycoprotein metabolic processGO:00091001160.016
hindbrain developmentGO:00309021280.016
ribonucleoside metabolic processGO:00091192450.016
sensory perceptionGO:00076002450.016
hematopoietic progenitor cell differentiationGO:00022441430.016
positive regulation of nervous system developmentGO:00519622210.016
cellular metal ion homeostasisGO:00068751510.016
nucleoside catabolic processGO:00091642060.016
single fertilizationGO:0007338820.016
positive regulation of apoptotic processGO:00430652170.016
negative regulation of protein modification processGO:00314001630.016
regulation of cytokine productionGO:00018172660.016
purine ribonucleoside triphosphate catabolic processGO:00092071990.016
synaptic transmissionGO:00072683290.016
response to molecule of bacterial originGO:00022371430.016
homeostasis of number of cells within a tissueGO:0048873250.016
kidney developmentGO:00018222130.016
purine nucleoside catabolic processGO:00061522050.016
chemotaxisGO:00069352470.016
nucleoside triphosphate catabolic processGO:00091432050.016
negative regulation of neuron apoptotic processGO:0043524920.016
exocytosisGO:00068871210.016
membrane organizationGO:00610242450.016
synaptic vesicle transportGO:0048489570.015
regulation of mapk cascadeGO:00434082480.015
regulation of body fluid levelsGO:00508781620.015
vesicle fusionGO:0006906160.015
regulation of epithelial cell proliferationGO:00506781410.015
fertilizationGO:00095661270.015
monocarboxylic acid metabolic processGO:00327871910.015
blood circulationGO:00080151950.015
sphingosine metabolic processGO:000667040.015
nucleoside phosphate catabolic processGO:19012922220.015
regulation of system processGO:00440572000.015
regulation of neuron differentiationGO:00456642810.015
renal system processGO:0003014480.015
regulation of synaptic growth at neuromuscular junctionGO:000858240.015
glycosaminoglycan metabolic processGO:0030203340.015
carbohydrate homeostasisGO:00335001280.015
organic acid transportGO:00158491010.015
nitrogen compound transportGO:00717052710.015
positive regulation of cell deathGO:00109422240.015
cell activation involved in immune responseGO:00022631260.015
purine nucleotide metabolic processGO:00061633020.015
purine ribonucleoside metabolic processGO:00461282410.015
bone developmentGO:00603481200.015
regulation of response to woundingGO:19030341890.015
positive regulation of cytokine productionGO:00018191740.015
positive regulation of cell developmentGO:00107202370.015
cellular nitrogen compound catabolic processGO:00442702800.015
ribonucleoside catabolic processGO:00424542060.015
cellular response to thyroid hormone stimulusGO:009706710.015
cellular response to hormone stimulusGO:00328701500.015
negative regulation of neuron deathGO:1901215980.014
vitamin metabolic processGO:0006766230.014
cellular response to growth factor stimulusGO:00713631970.014
muscle system processGO:00030121410.014
neutral lipid metabolic processGO:0006638570.014
regulation of protein maturationGO:1903317960.014
positive regulation of t cell mediated cytotoxicityGO:0001916150.014
muscle cell differentiationGO:00426922610.014
regulation of angiogenesisGO:0045765810.014
negative regulation of cell developmentGO:00107211690.014
negative regulation of intracellular signal transductionGO:19025321670.014
fat soluble vitamin biosynthetic processGO:004236240.014
ubiquitin dependent protein catabolic processGO:00065111290.014
regulation of homeostatic processGO:00328441820.014
meiotic cell cycleGO:00513211220.014
positive regulation of transferase activityGO:00513471670.014
epithelial cell migrationGO:0010631630.013
ribonucleoside triphosphate catabolic processGO:00092031990.013
response to interleukin 4GO:0070670230.013
regulation of protein kinase activityGO:00458592320.013
positive regulation of programmed cell deathGO:00430682180.013
regulation of cytoplasmic transportGO:19036491120.013
nucleobase containing small molecule metabolic processGO:00550863520.013
cellular response to organonitrogen compoundGO:00714171450.013
embryonic organ morphogenesisGO:00485622760.013
ensheathment of neuronsGO:0007272760.013
modification dependent macromolecule catabolic processGO:00436321330.013
positive regulation of cellular component biogenesisGO:0044089940.013
nucleoside metabolic processGO:00091162460.013
glycosylceramide metabolic processGO:000667740.013
carboxylic acid transportGO:00469421000.013
negative regulation of osteoblast proliferationGO:003368940.013
nucleotide catabolic processGO:00091662170.013
positive regulation of macroautophagyGO:001623930.013
lipid biosynthetic processGO:00086101790.013
aminoglycan metabolic processGO:0006022340.013
male gonad developmentGO:0008584880.013
phosphatidylinositol mediated signalingGO:0048015410.013
leukocyte differentiationGO:00025213420.013
defense response to gram positive bacteriumGO:0050830500.013
purine containing compound metabolic processGO:00725213110.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.013
establishment of synaptic vesicle localizationGO:0097480570.013
muscle cell developmentGO:00550011330.013
regulation of inflammatory responseGO:00507271470.013
positive regulation of immune effector processGO:00026991070.012
glucose homeostasisGO:00425931280.012
organonitrogen compound biosynthetic processGO:19015661920.012
synapse assemblyGO:0007416560.012
spermatogenesisGO:00072832840.012
gliogenesisGO:00420631410.012
positive regulation of innate immune responseGO:0045089800.012
positive regulation of peptidase activityGO:0010952490.012
regulation of systemic arterial blood pressureGO:0003073610.012
cytosolic calcium ion homeostasisGO:0051480700.012
microtubule based processGO:00070172360.012
extracellular matrix organizationGO:00301981470.012
gland developmentGO:00487323300.012
sterol metabolic processGO:0016125580.012
dephosphorylationGO:00163111290.012
posttranscriptional regulation of gene expressionGO:00106081550.012
regulation of neuron projection developmentGO:00109751690.012
sensory organ morphogenesisGO:00905962420.012
central nervous system neuron differentiationGO:00219531620.012
adult walking behaviorGO:0007628410.012
organic cyclic compound catabolic processGO:19013612950.012
lymphocyte proliferationGO:00466511640.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
modification dependent protein catabolic processGO:00199411330.012
response to peptideGO:19016521360.012
blood coagulationGO:0007596760.012
organic anion transportGO:00157111370.012
inorganic cation transmembrane transportGO:00986622070.012
organelle fusionGO:0048284280.012
negative regulation of protein phosphorylationGO:00019331260.012
establishment of organelle localizationGO:00516561220.011
monosaccharide metabolic processGO:00059961060.011
epithelial tube morphogenesisGO:00605623030.011
morphogenesis of a branching structureGO:00017632030.011
ear developmentGO:00435832000.011
carbohydrate metabolic processGO:00059752300.011
ribonucleoside triphosphate metabolic processGO:00091992200.011
regionalizationGO:00030023370.011
protein localization to cell leading edgeGO:190246310.011
homeostasis of number of cellsGO:00488722100.011
microtubule based movementGO:0007018840.011
cellular response to abiotic stimulusGO:0071214560.011
sensory perception of soundGO:0007605970.011
plasma membrane organizationGO:0007009900.011
negative regulation of vesicle fusionGO:003133910.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
interspecies interaction between organismsGO:0044419830.011
regulation of lymphocyte mediated immunityGO:0002706840.011
response to lipopolysaccharideGO:00324961280.011
multicellular organismal metabolic processGO:0044236280.011
glycosphingolipid metabolic processGO:0006687180.011
regulation of metal ion transportGO:00109591060.011
cell killingGO:0001906670.011
negative regulation of neuron differentiationGO:00456651010.011
cell maturationGO:00484691270.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
purine nucleoside triphosphate metabolic processGO:00091442260.011
sulfur compound metabolic processGO:00067901000.011
striated muscle cell developmentGO:00550021250.011
epithelial cell proliferationGO:00506731740.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
regulation of angiotensin levels in bloodGO:000200240.011
negative regulation of neuron projection developmentGO:0010977500.011
response to starvationGO:0042594650.011
positive regulation of cell adhesionGO:0045785800.011
negative regulation of mapk cascadeGO:0043409650.011
regulation of cytoskeleton organizationGO:00514931220.011
regulation of cellular response to stressGO:00801351590.011
regulation of bindingGO:00510981110.011
regulation of exocytosisGO:0017157610.011
organic hydroxy compound transportGO:0015850930.011
skeletal system morphogenesisGO:00487052030.011
telencephalon developmentGO:00215371860.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
lipid modificationGO:0030258650.011
nerve developmentGO:0021675670.011
positive regulation of organelle organizationGO:00106381280.011
fat cell differentiationGO:00454441600.011
endothelial cell migrationGO:0043542440.011
leukocyte proliferationGO:00706611720.010
feeding behaviorGO:0007631620.010
t cell proliferationGO:00420981200.010
organelle fissionGO:00482851700.010
regulation of systemic arterial blood pressure by carotid body chemoreceptor signalingGO:000302710.010
respiratory system developmentGO:00605411900.010
negative regulation of protein maturationGO:1903318790.010
leukocyte migrationGO:00509001240.010
hexose metabolic processGO:0019318980.010
cellular response to external stimulusGO:0071496880.010
leukocyte chemotaxisGO:0030595690.010
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:0001991130.010
phospholipid metabolic processGO:0006644870.010
dendrite developmentGO:00163581150.010
sensory system developmentGO:004888030.010
leukocyte activation involved in immune responseGO:00023661260.010
response to acid chemicalGO:00011011110.010
positive regulation of response to woundingGO:1903036660.010
negative regulation of cellular catabolic processGO:0031330470.010
natural killer cell activation involved in immune responseGO:0002323100.010
positive regulation of leukocyte mediated immunityGO:0002705700.010
neurotransmitter transportGO:0006836760.010
intrinsic apoptotic signaling pathwayGO:00971931320.010
cellular response to extracellular stimulusGO:0031668810.010
peptide transportGO:00158331330.010

Ctsa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.786
lysosomal storage diseaseDOID:321100.786
disease of metabolismDOID:001466700.786
lipid storage diseaseDOID:945500.786
nervous system diseaseDOID:86300.393
disease of anatomical entityDOID:700.393
central nervous system diseaseDOID:33100.393
brain diseaseDOID:93600.319
sphingolipidosisDOID:192700.270
cerebral degenerationDOID:144300.184
immune system diseaseDOID:291400.022
neurodegenerative diseaseDOID:128900.019
cognitive disorderDOID:156100.014
dementiaDOID:130700.014
disease of mental healthDOID:15000.014
lymphatic system diseaseDOID:7500.012