IMP: Integrative Multi-species Prediction

Mus musculus

30 known processes

Dad1

defender against cell death 1

(Aliases: AI323713)

Ensembl: ENSMUSG00000022174
Entrez: 13135
UniProtKB: P61804

Process Predictions
Disease Predictions

Dad1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
male gamete generation	GO:0048232	285	0.131
cation transport	GO:0006812	399	0.074
spermatogenesis	GO:0007283	284	0.064
cellular amino acid metabolic process	GO:0006520	103	0.061
inorganic ion transmembrane transport	GO:0098660	234	0.055
cation transmembrane transport	GO:0098655	266	0.053
localization within membrane	GO:0051668	4	0.052
membrane organization	GO:0061024	245	0.049
amine metabolic process	GO:0009308	45	0.044
cellular chemical homeostasis	GO:0055082	215	0.040
cellular amine metabolic process	GO:0044106	44	0.037
membrane lipid biosynthetic process	GO:0046467	32	0.037
skeletal system development	GO:0001501	356	0.036
ion transmembrane transport	GO:0034220	361	0.035
regulation of cellular amino acid metabolic process	GO:0006521	5	0.035
peptidyl amino acid modification	GO:0018193	336	0.034
regulation of cellular amine metabolic process	GO:0033238	20	0.033
cytoplasmic transport	GO:0016482	234	0.032
regulation of leukocyte differentiation	GO:1902105	159	0.030
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.028
cellular response to lipid	GO:0071396	145	0.027
regionalization	GO:0003002	337	0.026
response to acid chemical	GO:0001101	111	0.026
inorganic cation transmembrane transport	GO:0098662	207	0.025
organic hydroxy compound metabolic process	GO:1901615	203	0.024
adiponectin activated signaling pathway	GO:0033211	4	0.024
regulation of cell activation	GO:0050865	289	0.024
endomembrane system organization	GO:0010256	147	0.023
regulation of protein stability	GO:0031647	52	0.023
regulation of cell motility	GO:2000145	236	0.022
regulation of ion transport	GO:0043269	215	0.022
apoptotic signaling pathway	GO:0097190	306	0.022
myosin filament assembly	GO:0031034	2	0.022
metal ion homeostasis	GO:0055065	189	0.021
positive regulation of cellular amine metabolic process	GO:0033240	5	0.021
oxidation reduction process	GO:0055114	342	0.021
regulation of cellular ketone metabolic process	GO:0010565	66	0.021
nucleocytoplasmic transport	GO:0006913	139	0.021
bone development	GO:0060348	120	0.020
second messenger mediated signaling	GO:0019932	73	0.020
organonitrogen compound biosynthetic process	GO:1901566	192	0.020
monocarboxylic acid metabolic process	GO:0032787	191	0.020
posttranscriptional regulation of gene expression	GO:0010608	155	0.019
muscle cell differentiation	GO:0042692	261	0.019
mitotic cytokinesis	GO:0000281	4	0.019
regulation of lymphocyte activation	GO:0051249	240	0.019
organic acid biosynthetic process	GO:0016053	86	0.019
water soluble vitamin biosynthetic process	GO:0042364	3	0.018
response to organic cyclic compound	GO:0014070	198	0.018
phagocytosis	GO:0006909	66	0.018
single organism cell adhesion	GO:0098602	156	0.018
leukocyte differentiation	GO:0002521	342	0.018
regulation of ion transmembrane transport	GO:0034765	119	0.018
t cell activation	GO:0042110	289	0.018
sensory organ morphogenesis	GO:0090596	242	0.018
lymphocyte differentiation	GO:0030098	242	0.017
striated muscle myosin thick filament assembly	GO:0071688	1	0.017
citrulline metabolic process	GO:0000052	3	0.017
negative regulation of protein metabolic process	GO:0051248	282	0.017
t cell differentiation	GO:0030217	174	0.017
mapk cascade	GO:0000165	281	0.017
regulation of transmembrane transport	GO:0034762	128	0.017
protein localization to nucleus	GO:0034504	121	0.017
wnt signaling pathway	GO:0016055	188	0.016
golgi vesicle transport	GO:0048193	30	0.016
copii coated vesicle budding	GO:0090114	2	0.016
actin cytoskeleton organization	GO:0030036	220	0.016
regulation of transferase activity	GO:0051338	263	0.016
engulfment of apoptotic cell	GO:0043652	3	0.016
carboxylic acid biosynthetic process	GO:0046394	86	0.016
regulation of kinase activity	GO:0043549	249	0.016
nuclear import	GO:0051170	95	0.016
regulation of t cell activation	GO:0050863	170	0.015
regulation of lymphocyte differentiation	GO:0045619	107	0.015
spermatid differentiation	GO:0048515	115	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.015
regulation of wnt signaling pathway	GO:0030111	123	0.015
protein localization to organelle	GO:0033365	185	0.014
regulation of protein kinase activity	GO:0045859	232	0.014
peptidyl proline hydroxylation	GO:0019511	3	0.014
connective tissue development	GO:0061448	179	0.014
negative regulation of cellular protein metabolic process	GO:0032269	247	0.014
response to organonitrogen compound	GO:0010243	246	0.014
transmembrane transport	GO:0055085	412	0.014
er to golgi vesicle mediated transport	GO:0006888	11	0.014
regulation of hormone levels	GO:0010817	211	0.014
embryonic organ morphogenesis	GO:0048562	276	0.014
regulation of organelle organization	GO:0033043	289	0.014
cellular homeostasis	GO:0019725	240	0.014
spermatid development	GO:0007286	108	0.013
l ascorbic acid metabolic process	GO:0019852	4	0.013
regulation of secretion	GO:0051046	274	0.013
cellular modified amino acid metabolic process	GO:0006575	63	0.013
regulation of canonical wnt signaling pathway	GO:0060828	82	0.013
nuclear transport	GO:0051169	139	0.013
small molecule biosynthetic process	GO:0044283	132	0.013
gland development	GO:0048732	330	0.013
peptide transport	GO:0015833	133	0.013
cartilage development	GO:0051216	140	0.013
epithelial cell proliferation	GO:0050673	174	0.013
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.012
cellular component assembly involved in morphogenesis	GO:0010927	139	0.012
divalent inorganic cation transport	GO:0072511	178	0.012
response to steroid hormone	GO:0048545	56	0.012
regulation of protein localization	GO:0032880	231	0.012
regulation of t cell differentiation	GO:0045580	83	0.012
peptidyl proline modification	GO:0018208	6	0.012
regulation of hydrolase activity	GO:0051336	246	0.012
ameboidal type cell migration	GO:0001667	128	0.012
canonical wnt signaling pathway	GO:0060070	130	0.012
cognition	GO:0050890	149	0.012
regulation of multi organism process	GO:0043900	111	0.012
protein import into nucleus	GO:0006606	95	0.012
cellular protein complex assembly	GO:0043623	116	0.012
cellular glucose homeostasis	GO:0001678	52	0.012
sensory system development	GO:0048880	3	0.012
cytokine production	GO:0001816	319	0.012
leukocyte migration	GO:0050900	124	0.012
cytokine mediated signaling pathway	GO:0019221	115	0.012
response to retinoic acid	GO:0032526	56	0.012
renal system development	GO:0072001	225	0.012
regulation of cellular response to stress	GO:0080135	159	0.011
response to inorganic substance	GO:0010035	96	0.011
response to light stimulus	GO:0009416	135	0.011
extracellular structure organization	GO:0043062	148	0.011
regulation of cell projection organization	GO:0031344	206	0.011
learning	GO:0007612	98	0.011
positive regulation of cell death	GO:0010942	224	0.011
organic cyclic compound catabolic process	GO:1901361	295	0.011
steroid metabolic process	GO:0008202	119	0.011
glycoprotein biosynthetic process	GO:0009101	89	0.011
regulation of secretion by cell	GO:1903530	249	0.011
regulation of t cell differentiation in thymus	GO:0033081	24	0.011
cellular response to molecule of bacterial origin	GO:0071219	83	0.011
glucose homeostasis	GO:0042593	128	0.011
cellular response to lipopolysaccharide	GO:0071222	77	0.011
cellular lipid metabolic process	GO:0044255	323	0.011
leukocyte proliferation	GO:0070661	172	0.011
regulation of leukocyte proliferation	GO:0070663	121	0.011
transition metal ion transport	GO:0000041	38	0.011
cardiocyte differentiation	GO:0035051	87	0.011
single organism nuclear import	GO:1902593	95	0.011
positive regulation of cell motility	GO:2000147	116	0.011
positive regulation of necrotic cell death	GO:0010940	1	0.011
regulation of cell migration	GO:0030334	219	0.011
camera type eye development	GO:0043010	266	0.011
negative regulation of neuron differentiation	GO:0045665	101	0.011
positive regulation of cell development	GO:0010720	237	0.011
alcohol metabolic process	GO:0006066	116	0.011
retrograde vesicle mediated transport golgi to er	GO:0006890	1	0.010
hematopoietic progenitor cell differentiation	GO:0002244	143	0.010
learning or memory	GO:0007611	148	0.010
mitotic cell cycle process	GO:1903047	159	0.010
purine containing compound metabolic process	GO:0072521	311	0.010
stem cell differentiation	GO:0048863	268	0.010
lipid biosynthetic process	GO:0008610	179	0.010
regulation of phagocytosis	GO:0050764	33	0.010
myosin filament organization	GO:0031033	3	0.010
cell growth	GO:0016049	130	0.010
multicellular organism growth	GO:0035264	161	0.010
organic hydroxy compound biosynthetic process	GO:1901617	77	0.010

Dad1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.092
connective tissue disease	DOID:65	0.092
disease of anatomical entity	DOID:7	0.092
bone disease	DOID:0080001	0.092
bone development disease	DOID:0080006	0.092
osteochondrodysplasia	DOID:2256	0.033
nervous system disease	DOID:863	0.033
central nervous system disease	DOID:331	0.017
neurodegenerative disease	DOID:1289	0.012

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