IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Ech1

enoyl coenzyme A hydratase 1, peroxisomal

(Aliases: MGC107274,AA617331)

Entrez: 51798
Ensembl: ENSMUSG00000053898
UniProtKB: O35459

Process Predictions
Disease Predictions

Ech1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cellular lipid catabolic process	GO:0044242	52	1.000
small molecule catabolic process	GO:0044282	71	0.997
fatty acid oxidation	GO:0019395	28	0.994
lipid catabolic process	GO:0016042	69	0.992
monocarboxylic acid catabolic process	GO:0072329	27	0.990
lipid oxidation	GO:0034440	29	0.990
fatty acid catabolic process	GO:0009062	25	0.973
carboxylic acid catabolic process	GO:0046395	51	0.965
fatty acid beta oxidation	GO:0006635	16	0.955
oxidation reduction process	GO:0055114	342	0.950
monocarboxylic acid metabolic process	GO:0032787	191	0.945
sulfur compound metabolic process	GO:0006790	100	0.932
lipid modification	GO:0030258	65	0.930
cellular lipid metabolic process	GO:0044255	323	0.876
fatty acid metabolic process	GO:0006631	121	0.866
organic acid catabolic process	GO:0016054	51	0.639
thioester metabolic process	GO:0035383	19	0.607
protein tetramerization	GO:0051262	23	0.496
acyl coa metabolic process	GO:0006637	19	0.364
cellular ketone metabolic process	GO:0042180	84	0.332
cofactor metabolic process	GO:0051186	80	0.286
very long chain fatty acid catabolic process	GO:0042760	2	0.284
protein oligomerization	GO:0051259	67	0.161
organic hydroxy compound metabolic process	GO:1901615	203	0.129
regulation of hormone levels	GO:0010817	211	0.129
steroid metabolic process	GO:0008202	119	0.124
response to organic cyclic compound	GO:0014070	198	0.117
modification dependent protein catabolic process	GO:0019941	133	0.109
protein homooligomerization	GO:0051260	43	0.106
regulation of cellular catabolic process	GO:0031329	242	0.105
negative regulation of cellular protein metabolic process	GO:0032269	247	0.104
regulation of cellular ketone metabolic process	GO:0010565	66	0.102
cellular macromolecule catabolic process	GO:0044265	206	0.098
hormone metabolic process	GO:0042445	86	0.097
small molecule biosynthetic process	GO:0044283	132	0.097
fatty acid alpha oxidation	GO:0001561	2	0.096
hydrogen ion transmembrane transport	GO:1902600	25	0.090
cellular amino acid metabolic process	GO:0006520	103	0.080
maintenance of location	GO:0051235	89	0.075
retinoid metabolic process	GO:0001523	24	0.068
ubiquitin dependent protein catabolic process	GO:0006511	129	0.065
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.065
cellular amine metabolic process	GO:0044106	44	0.062
regulation of cellular amino acid metabolic process	GO:0006521	5	0.059
glutathione metabolic process	GO:0006749	16	0.058
macromolecule catabolic process	GO:0009057	281	0.057
microtubule based process	GO:0007017	236	0.056
cation transport	GO:0006812	399	0.056
defense response to bacterium	GO:0042742	119	0.052
response to starvation	GO:0042594	65	0.051
negative regulation of protein metabolic process	GO:0051248	282	0.050
negative regulation of cell proliferation	GO:0008285	296	0.048
negative regulation of fatty acid oxidation	GO:0046322	5	0.048
protein catabolic process	GO:0030163	221	0.047
reactive nitrogen species metabolic process	GO:2001057	0	0.047
cellular modified amino acid metabolic process	GO:0006575	63	0.045
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.044
modification dependent macromolecule catabolic process	GO:0043632	133	0.044
defense response to other organism	GO:0098542	197	0.043
positive regulation of mitochondrial membrane permeability involved in apoptotic process	GO:1902110	11	0.043
regulation of attachment of spindle microtubules to kinetochore	GO:0051988	3	0.042
regulation of lipid metabolic process	GO:0019216	118	0.041
epithelial cell development	GO:0002064	159	0.040
response to oxidative stress	GO:0006979	123	0.040
reactive oxygen species metabolic process	GO:0072593	84	0.039
regulation of intracellular transport	GO:0032386	159	0.038
neuronal action potential	GO:0019228	54	0.038
protein processing	GO:0016485	163	0.037
proteasomal protein catabolic process	GO:0010498	98	0.037
protein maturation	GO:0051604	176	0.037
nucleobase containing small molecule metabolic process	GO:0055086	352	0.037
membrane organization	GO:0061024	245	0.036
carnitine metabolic process	GO:0009437	7	0.035
cellular protein catabolic process	GO:0044257	155	0.035
terpenoid metabolic process	GO:0006721	25	0.035
lipid biosynthetic process	GO:0008610	179	0.035
coenzyme catabolic process	GO:0009109	5	0.035
response to extracellular stimulus	GO:0009991	127	0.034
response to steroid hormone	GO:0048545	56	0.033
very long chain fatty acid metabolic process	GO:0000038	8	0.032
positive regulation of cell development	GO:0010720	237	0.031
regulation of organelle organization	GO:0033043	289	0.031
cellular amide metabolic process	GO:0043603	58	0.031
regulation of proteasomal protein catabolic process	GO:0061136	46	0.030
response to nutrient levels	GO:0031667	109	0.030
cellular response to hypoxia	GO:0071456	17	0.029
negative regulation of protein modification process	GO:0031400	163	0.029
ossification	GO:0001503	216	0.029
negative regulation of proteolysis	GO:0045861	74	0.028
amine metabolic process	GO:0009308	45	0.027
nucleoside phosphate metabolic process	GO:0006753	338	0.027
positive regulation of cellular amine metabolic process	GO:0033240	5	0.026
lipid localization	GO:0010876	126	0.026
cellular response to oxygen levels	GO:0071453	20	0.026
cellular response to extracellular stimulus	GO:0031668	81	0.025
regulation of proteolysis	GO:0030162	164	0.025
organic hydroxy compound biosynthetic process	GO:1901617	77	0.025
regulation of apoptotic signaling pathway	GO:2001233	197	0.025
endomembrane system organization	GO:0010256	147	0.024
transmission of nerve impulse	GO:0019226	76	0.024
negative regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032435	15	0.024
multicellular organismal signaling	GO:0035637	91	0.024
peptidyl amino acid modification	GO:0018193	336	0.023
regulation of cytoskeleton organization	GO:0051493	122	0.023
negative regulation of cellular component organization	GO:0051129	194	0.023
isoprenoid metabolic process	GO:0006720	29	0.023
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.023
negative regulation of protein processing	GO:0010955	79	0.023
regulation of hydrolase activity	GO:0051336	246	0.023
positive regulation of secretion by cell	GO:1903532	114	0.022
carboxylic acid biosynthetic process	GO:0046394	86	0.022
positive regulation of mitochondrial membrane permeability	GO:0035794	12	0.022
microtubule cytoskeleton organization	GO:0000226	157	0.021
negative regulation of protein maturation	GO:1903318	79	0.021
protein homotetramerization	GO:0051289	12	0.021
cellular response to oxidative stress	GO:0034599	76	0.020
cellular response to external stimulus	GO:0071496	88	0.020
negative regulation of mitochondrion organization	GO:0010823	9	0.020
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.019
regulation of chromosome segregation	GO:0051983	21	0.019
regulation of protein maturation	GO:1903317	96	0.019
liver development	GO:0001889	66	0.019
response to catecholamine	GO:0071869	4	0.019
organic acid biosynthetic process	GO:0016053	86	0.018
lipid storage	GO:0019915	36	0.018
regulation of fatty acid beta oxidation	GO:0031998	1	0.018
response to organonitrogen compound	GO:0010243	246	0.018
regulation of cellular amine metabolic process	GO:0033238	20	0.017
renal system development	GO:0072001	225	0.017
regulation of fibroblast growth factor production	GO:0090270	4	0.017
negative regulation of molecular function	GO:0044092	258	0.017
androgen metabolic process	GO:0008209	11	0.017
histone h3 deacetylation	GO:0070932	8	0.016
regulation of defense response	GO:0031347	233	0.016
regulation of protein processing	GO:0070613	96	0.016
negative regulation of hydrolase activity	GO:0051346	71	0.016
negative regulation of organelle organization	GO:0010639	90	0.016
mitochondrial transport	GO:0006839	36	0.016
transmembrane transport	GO:0055085	412	0.016
mitochondrion organization	GO:0007005	134	0.016
ion transmembrane transport	GO:0034220	361	0.016
divalent metal ion transport	GO:0070838	172	0.016
regulation of protein catabolic process	GO:0042176	108	0.016
regulation of cellular protein catabolic process	GO:1903362	61	0.016
positive regulation of chromosome segregation	GO:0051984	4	0.016
nucleotide metabolic process	GO:0009117	332	0.016
schwann cell differentiation	GO:0014037	26	0.015
succinyl coa metabolic process	GO:0006104	1	0.015
substantia nigra development	GO:0021762	2	0.015
regulation of secretion by cell	GO:1903530	249	0.015
action potential	GO:0001508	78	0.015
positive regulation of oocyte development	GO:0060282	4	0.015
water soluble vitamin biosynthetic process	GO:0042364	3	0.015
innate immune response	GO:0045087	157	0.014
myelination in peripheral nervous system	GO:0022011	19	0.014
negative regulation of fatty acid metabolic process	GO:0045922	10	0.014
alcohol metabolic process	GO:0006066	116	0.014
ensheathment of neurons	GO:0007272	76	0.014
cellular response to organonitrogen compound	GO:0071417	145	0.014
glycogen metabolic process	GO:0005977	32	0.014
inorganic ion transmembrane transport	GO:0098660	234	0.014
negative regulation of proteolysis involved in cellular protein catabolic process	GO:1903051	22	0.014
development of primary sexual characteristics	GO:0045137	143	0.014
hematopoietic progenitor cell differentiation	GO:0002244	143	0.013
attachment of spindle microtubules to kinetochore	GO:0008608	4	0.013
apoptotic mitochondrial changes	GO:0008637	48	0.013
connective tissue development	GO:0061448	179	0.013
positive regulation of secretion	GO:0051047	130	0.013
gonad development	GO:0008406	141	0.013
response to molecule of bacterial origin	GO:0002237	143	0.013
male gonad development	GO:0008584	88	0.013
negative regulation of cellular amine metabolic process	GO:0033239	1	0.012
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	56	0.012
negative regulation of nlrp3 inflammasome complex assembly	GO:1900226	2	0.012
quinone metabolic process	GO:1901661	7	0.012
negative regulation of phosphorylation	GO:0042326	166	0.012
regulation of secretion	GO:0051046	274	0.012
positive regulation of meiosis	GO:0045836	14	0.012
cellular protein complex assembly	GO:0043623	116	0.012
cellular response to catecholamine stimulus	GO:0071870	3	0.011
regulation of defense response to bacterium	GO:1900424	3	0.011
carbohydrate biosynthetic process	GO:0016051	74	0.011
response to hypoxia	GO:0001666	58	0.011
nitrogen compound transport	GO:0071705	271	0.011
response to decreased oxygen levels	GO:0036293	59	0.011
nephron development	GO:0072006	109	0.011
regulation of cholesterol metabolic process	GO:0090181	14	0.011
inorganic cation transmembrane transport	GO:0098662	207	0.011
acetyl coa metabolic process	GO:0006084	8	0.011
myelination	GO:0042552	74	0.011
regulation of membrane potential	GO:0042391	192	0.011
regulation of ossification	GO:0030278	112	0.011
male gamete generation	GO:0048232	285	0.011
organophosphate biosynthetic process	GO:0090407	122	0.011
chemotaxis	GO:0006935	247	0.011
hormone secretion	GO:0046879	128	0.011
plasma membrane organization	GO:0007009	90	0.011
positive regulation of organelle organization	GO:0010638	128	0.011
glial cell development	GO:0021782	54	0.010
regulation of nlrp3 inflammasome complex assembly	GO:1900225	4	0.010
regulation of osteoblast differentiation	GO:0045667	67	0.010
carbohydrate metabolic process	GO:0005975	230	0.010
organonitrogen compound biosynthetic process	GO:1901566	192	0.010
diterpenoid metabolic process	GO:0016101	24	0.010
negative regulation of protein catabolic process	GO:0042177	36	0.010
negative regulation of phosphorus metabolic process	GO:0010563	184	0.010
regulation of binding	GO:0051098	111	0.010
skeletal system development	GO:0001501	356	0.010
female gamete generation	GO:0007292	74	0.010

Ech1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
inherited metabolic disorder	DOID:655	0.637
carbohydrate metabolic disorder	DOID:2978	0.637
hyperinsulinemic hypoglycemia	DOID:13317	0.637
disease of metabolism	DOID:0014667	0.637
sensory system disease	DOID:0050155	0.012
disease of anatomical entity	DOID:7	0.012
nervous system disease	DOID:863	0.012

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