IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Efhc1

EF-hand domain (C-terminal) containing 1

(Aliases: mRib72-1,1700029F22Rik,myoclonin1)

Ensembl: ENSMUSG00000041809
Entrez: 71877
UniProtKB: B2CKC6
UniProtKB: Q9D9T8

Process Predictions
Disease Predictions

Efhc1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cilium morphogenesis	GO:0060271	102	0.257
cilium assembly	GO:0042384	81	0.156
intraciliary retrograde transport	GO:0035721	3	0.104
microtubule based movement	GO:0007018	84	0.066
cellular component assembly involved in morphogenesis	GO:0010927	139	0.064
organelle assembly	GO:0070925	177	0.063
smoothened signaling pathway	GO:0007224	105	0.048
spermatogenesis	GO:0007283	284	0.040
male gamete generation	GO:0048232	285	0.040
cytoskeleton dependent intracellular transport	GO:0030705	50	0.038
nucleotide metabolic process	GO:0009117	332	0.037
ribose phosphate metabolic process	GO:0019693	291	0.036
organonitrogen compound catabolic process	GO:1901565	264	0.032
purine containing compound metabolic process	GO:0072521	311	0.031
ribonucleotide metabolic process	GO:0009259	291	0.030
cellular amino acid metabolic process	GO:0006520	103	0.030
ras protein signal transduction	GO:0007265	77	0.030
nucleoside phosphate metabolic process	GO:0006753	338	0.030
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.029
camera type eye development	GO:0043010	266	0.028
ribonucleoside metabolic process	GO:0009119	245	0.028
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.028
amine metabolic process	GO:0009308	45	0.028
purine containing compound catabolic process	GO:0072523	213	0.027
nucleobase containing small molecule metabolic process	GO:0055086	352	0.027
purine nucleotide catabolic process	GO:0006195	211	0.026
nucleoside metabolic process	GO:0009116	246	0.025
heterocycle catabolic process	GO:0046700	280	0.025
nucleoside phosphate catabolic process	GO:1901292	222	0.025
purine nucleoside catabolic process	GO:0006152	205	0.025
sensory organ morphogenesis	GO:0090596	242	0.025
organophosphate catabolic process	GO:0046434	232	0.024
carbohydrate derivative catabolic process	GO:1901136	231	0.024
purine nucleotide metabolic process	GO:0006163	302	0.024
nucleoside triphosphate metabolic process	GO:0009141	230	0.024
cation transport	GO:0006812	399	0.024
aromatic compound catabolic process	GO:0019439	286	0.023
glycosyl compound metabolic process	GO:1901657	246	0.023
regulation of cellular amine metabolic process	GO:0033238	20	0.023
purine ribonucleotide metabolic process	GO:0009150	290	0.023
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.023
cellular amine metabolic process	GO:0044106	44	0.022
cellular nitrogen compound catabolic process	GO:0044270	280	0.022
microtubule based process	GO:0007017	236	0.022
negative regulation of cell proliferation	GO:0008285	296	0.022
small gtpase mediated signal transduction	GO:0007264	97	0.021
nucleoside triphosphate catabolic process	GO:0009143	205	0.021
fat cell differentiation	GO:0045444	160	0.021
purine nucleoside metabolic process	GO:0042278	241	0.021
nucleoside catabolic process	GO:0009164	206	0.021
organic cyclic compound catabolic process	GO:1901361	295	0.021
glycosyl compound catabolic process	GO:1901658	206	0.021
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.020
membrane organization	GO:0061024	245	0.020
cellular chemical homeostasis	GO:0055082	215	0.020
regulation of cellular amino acid metabolic process	GO:0006521	5	0.020
regulation of cellular ketone metabolic process	GO:0010565	66	0.020
nucleotide catabolic process	GO:0009166	217	0.020
ribonucleoside catabolic process	GO:0042454	206	0.020
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.019
cellular lipid metabolic process	GO:0044255	323	0.019
regulation of organelle organization	GO:0033043	289	0.019
protein localization to organelle	GO:0033365	185	0.019
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.019
organelle localization	GO:0051640	179	0.018
regulation of smoothened signaling pathway	GO:0008589	58	0.018
transmembrane transport	GO:0055085	412	0.018
ribonucleotide catabolic process	GO:0009261	208	0.018
cellular homeostasis	GO:0019725	240	0.018
positive regulation of cellular amine metabolic process	GO:0033240	5	0.017
carbohydrate metabolic process	GO:0005975	230	0.017
regulation of nucleotide metabolic process	GO:0006140	169	0.017
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.017
purine ribonucleotide catabolic process	GO:0009154	208	0.017
purine ribonucleoside metabolic process	GO:0046128	241	0.017
establishment of vesicle localization	GO:0051650	81	0.017
retina development in camera type eye	GO:0060041	119	0.017
vesicle localization	GO:0051648	86	0.017
germ cell development	GO:0007281	185	0.016
oxidation reduction process	GO:0055114	342	0.016
sequestering of metal ion	GO:0051238	19	0.016
organelle fission	GO:0048285	170	0.016
apoptotic signaling pathway	GO:0097190	306	0.016
carbohydrate derivative biosynthetic process	GO:1901137	183	0.015
cation transmembrane transport	GO:0098655	266	0.015
organonitrogen compound biosynthetic process	GO:1901566	192	0.015
macromolecule catabolic process	GO:0009057	281	0.015
guanosine containing compound metabolic process	GO:1901068	144	0.015
microtubule based transport	GO:0010970	50	0.015
forebrain development	GO:0030900	302	0.015
sensory perception	GO:0007600	245	0.015
gtp metabolic process	GO:0046039	144	0.015
epithelial cell proliferation	GO:0050673	174	0.014
regulation of purine nucleotide metabolic process	GO:1900542	169	0.014
regulation of hydrolase activity	GO:0051336	246	0.014
embryonic organ morphogenesis	GO:0048562	276	0.014
cellular ketone metabolic process	GO:0042180	84	0.014
intraciliary transport	GO:0042073	9	0.014
regulation of cellular catabolic process	GO:0031329	242	0.014
ventricular system development	GO:0021591	27	0.014
fertilization	GO:0009566	127	0.014
positive regulation of cell death	GO:0010942	224	0.014
establishment of organelle localization	GO:0051656	122	0.014
sperm motility	GO:0030317	47	0.014
posttranscriptional regulation of gene expression	GO:0010608	155	0.014
regulation of nucleoside metabolic process	GO:0009118	130	0.013
telencephalon development	GO:0021537	186	0.013
cytoplasmic transport	GO:0016482	234	0.013
response to organonitrogen compound	GO:0010243	246	0.013
nuclear division	GO:0000280	158	0.013
reactive oxygen species metabolic process	GO:0072593	84	0.013
ossification	GO:0001503	216	0.013
spermatid development	GO:0007286	108	0.013
cellular response to organonitrogen compound	GO:0071417	145	0.013
regulation of purine nucleotide catabolic process	GO:0033121	122	0.013
guanosine containing compound catabolic process	GO:1901069	144	0.013
anatomical structure homeostasis	GO:0060249	145	0.013
regulation of cell motility	GO:2000145	236	0.013
positive regulation of programmed cell death	GO:0043068	218	0.013
glycoprotein metabolic process	GO:0009100	116	0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.013
carbohydrate homeostasis	GO:0033500	128	0.012
regulation of cell activation	GO:0050865	289	0.012
protein maturation	GO:0051604	176	0.012
positive regulation of protein phosphorylation	GO:0001934	242	0.012
positive regulation of nervous system development	GO:0051962	221	0.012
retrograde transport endosome to golgi	GO:0042147	2	0.012
digestive system development	GO:0055123	200	0.012
regulation of apoptotic signaling pathway	GO:2001233	197	0.012
immune effector process	GO:0002252	321	0.012
digestive tract development	GO:0048565	190	0.012
cellular macromolecule catabolic process	GO:0044265	206	0.012
divalent metal ion transport	GO:0070838	172	0.012
peptidyl amino acid modification	GO:0018193	336	0.012
skeletal system development	GO:0001501	356	0.012
monocarboxylic acid metabolic process	GO:0032787	191	0.012
positive regulation of cell development	GO:0010720	237	0.012
regulation of secretion	GO:0051046	274	0.012
cellularization	GO:0007349	1	0.012
multicellular organismal homeostasis	GO:0048871	164	0.012
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.012
rho protein signal transduction	GO:0007266	32	0.012
protein localization to membrane	GO:0072657	108	0.012
protein catabolic process	GO:0030163	221	0.012
positive regulation of protein modification process	GO:0031401	299	0.012
spermatid differentiation	GO:0048515	115	0.012
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.012
regulation of secretion by cell	GO:1903530	249	0.012
microtubule cytoskeleton organization	GO:0000226	157	0.012
renal system development	GO:0072001	225	0.011
regionalization	GO:0003002	337	0.011
divalent inorganic cation transport	GO:0072511	178	0.011
g protein coupled receptor signaling pathway	GO:0007186	243	0.011
regulation of cell migration	GO:0030334	219	0.011
sequestering of calcium ion	GO:0051208	18	0.011
oocyte axis specification	GO:0007309	2	0.011
inorganic cation transmembrane transport	GO:0098662	207	0.011
regulation of cellular component biogenesis	GO:0044087	181	0.011
mapk cascade	GO:0000165	281	0.011
regulation of nucleotide catabolic process	GO:0030811	122	0.011
hematopoietic progenitor cell differentiation	GO:0002244	143	0.011
dna repair	GO:0006281	107	0.011
reactive nitrogen species metabolic process	GO:2001057	0	0.011
purine ribonucleoside catabolic process	GO:0046130	205	0.011
regulation of cell cycle	GO:0051726	281	0.011
regulation of membrane potential	GO:0042391	192	0.011
nitrogen compound transport	GO:0071705	271	0.011
positive regulation of nucleotide metabolic process	GO:0045981	114	0.011
positive regulation of hydrolase activity	GO:0051345	148	0.011
inflammatory response	GO:0006954	244	0.011
kidney development	GO:0001822	213	0.011
extracellular matrix organization	GO:0030198	147	0.011
ion transmembrane transport	GO:0034220	361	0.011
leukocyte migration	GO:0050900	124	0.011
regulation of mapk cascade	GO:0043408	248	0.011
negative regulation of nervous system development	GO:0051961	156	0.011
sulfur compound metabolic process	GO:0006790	100	0.011
negative regulation of cellular component organization	GO:0051129	194	0.010
meiotic cell cycle	GO:0051321	122	0.010
regulation of cytokine production	GO:0001817	266	0.010
morphogenesis of embryonic epithelium	GO:0016331	159	0.010
endocytosis	GO:0006897	168	0.010
epithelial cell development	GO:0002064	159	0.010
establishment of melanosome localization	GO:0032401	11	0.010
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.010
generation of precursor metabolites and energy	GO:0006091	103	0.010
cilium movement	GO:0003341	28	0.010
intracellular protein transport	GO:0006886	204	0.010
melanosome localization	GO:0032400	12	0.010
extracellular structure organization	GO:0043062	148	0.010
regulation of transferase activity	GO:0051338	263	0.010
rna interference	GO:0016246	2	0.010
regulation of hormone levels	GO:0010817	211	0.010
neural tube development	GO:0021915	160	0.010
leukocyte differentiation	GO:0002521	342	0.010
adult behavior	GO:0030534	135	0.010
epithelial cilium movement	GO:0003351	12	0.010
epithelial tube formation	GO:0072175	130	0.010
cellular response to dna damage stimulus	GO:0006974	207	0.010
positive regulation of apoptotic process	GO:0043065	217	0.010

Efhc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability	Func Analog Org
nervous system disease	DOID:863	0.026	Human
sensory system disease	DOID:0050155	0.026
disease of anatomical entity	DOID:7	0.026	Human
eye and adnexa disease	DOID:1492	0.026
eye disease	DOID:5614	0.016
cancer	DOID:162	0.012
disease of cellular proliferation	DOID:14566	0.012
organ system cancer	DOID:0050686	0.012
immune system disease	DOID:2914	0.011
disease of metabolism	DOID:0014667	0.010
central nervous system disease	DOID:331	0.010	Human
connective tissue disease	DOID:65	0.010
bone disease	DOID:0080001	0.010
musculoskeletal system disease	DOID:17	0.010

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