IMP: Integrative Multi-species Prediction

Mus musculus

18 known processes

Eif3e

eukaryotic translation initiation factor 3, subunit E

(Aliases: Eif3s6,Int6,eIF3-p48,eIF3-p46,48kDa)

Ensembl: ENSMUSG00000022336
Entrez: 16341
UniProtKB: Q3UIG0
UniProtKB: P60229

Process Predictions
Disease Predictions

Eif3e biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
nuclear division	GO:0000280	158	0.130
translational initiation	GO:0006413	24	0.125
cytoplasmic translational initiation	GO:0002183	3	0.073
mitotic cell cycle	GO:0000278	195	0.061
organelle fission	GO:0048285	170	0.061
development of primary sexual characteristics	GO:0045137	143	0.057
nucleotide metabolic process	GO:0009117	332	0.056
microtubule cytoskeleton organization involved in mitosis	GO:1902850	4	0.050
microtubule cytoskeleton organization	GO:0000226	157	0.049
multicellular organism growth	GO:0035264	161	0.049
cell cell recognition	GO:0009988	44	0.049
spindle assembly involved in mitosis	GO:0090307	4	0.048
small gtpase mediated signal transduction	GO:0007264	97	0.047
positive regulation of apoptotic process	GO:0043065	217	0.046
positive regulation of cell death	GO:0010942	224	0.045
striated muscle tissue development	GO:0014706	293	0.043
meiotic nuclear division	GO:0007126	115	0.040
meiotic cell cycle	GO:0051321	122	0.040
skeletal muscle organ development	GO:0060538	163	0.039
cell division	GO:0051301	120	0.038
nucleoside phosphate metabolic process	GO:0006753	338	0.037
mitotic cell cycle process	GO:1903047	159	0.037
apoptotic signaling pathway	GO:0097190	306	0.036
nucleoside phosphate catabolic process	GO:1901292	222	0.035
organonitrogen compound catabolic process	GO:1901565	264	0.033
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.033
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.033
male gamete generation	GO:0048232	285	0.032
cell type specific apoptotic process	GO:0097285	268	0.032
genitalia development	GO:0048806	37	0.031
regulation of cell cycle	GO:0051726	281	0.031
rna interference	GO:0016246	2	0.030
positive regulation of growth	GO:0045927	104	0.030
microtubule based process	GO:0007017	236	0.029
organophosphate catabolic process	GO:0046434	232	0.029
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.028
striated muscle cell development	GO:0055002	125	0.028
ras protein signal transduction	GO:0007265	77	0.027
maintenance of location	GO:0051235	89	0.027
muscle tissue development	GO:0060537	308	0.027
regulation of cellular component biogenesis	GO:0044087	181	0.026
single fertilization	GO:0007338	82	0.025
ribosomal small subunit biogenesis	GO:0042274	4	0.024
regulation of apoptotic signaling pathway	GO:2001233	197	0.024
rab protein signal transduction	GO:0032482	1	0.023
regulation of organelle organization	GO:0033043	289	0.022
positive regulation of hydrolase activity	GO:0051345	148	0.022
female gamete generation	GO:0007292	74	0.022
binding of sperm to zona pellucida	GO:0007339	34	0.022
purine nucleoside catabolic process	GO:0006152	205	0.021
organic cyclic compound catabolic process	GO:1901361	295	0.021	Human
nucleoside triphosphate catabolic process	GO:0009143	205	0.021
rna processing	GO:0006396	105	0.021
posttranscriptional regulation of gene expression	GO:0010608	155	0.020
purine ribonucleoside catabolic process	GO:0046130	205	0.020
regulation of cellular amino acid metabolic process	GO:0006521	5	0.020
t cell activation	GO:0042110	289	0.019
purine ribonucleotide metabolic process	GO:0009150	290	0.019
heterocycle catabolic process	GO:0046700	280	0.019	Human
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.018
regulation of mapk cascade	GO:0043408	248	0.018
myotube differentiation	GO:0014902	105	0.018
regulation of meiotic cell cycle	GO:0051445	34	0.018
spermatogenesis	GO:0007283	284	0.018
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.018
rna splicing	GO:0008380	54	0.017
purine containing compound metabolic process	GO:0072521	311	0.017
nucleotide catabolic process	GO:0009166	217	0.017
oocyte axis specification	GO:0007309	2	0.017
purine ribonucleoside metabolic process	GO:0046128	241	0.016
ribonucleoside catabolic process	GO:0042454	206	0.016
ribonucleoside metabolic process	GO:0009119	245	0.016
endocytosis	GO:0006897	168	0.016
cellular amino acid metabolic process	GO:0006520	103	0.016
protein processing	GO:0016485	163	0.016
positive regulation of programmed cell death	GO:0043068	218	0.016
translation	GO:0006412	93	0.016
sperm egg recognition	GO:0035036	37	0.016
regulation of cellular amine metabolic process	GO:0033238	20	0.016
regulation of cellular response to stress	GO:0080135	159	0.015
purine ribonucleotide catabolic process	GO:0009154	208	0.015
organelle assembly	GO:0070925	177	0.015
ribonucleotide catabolic process	GO:0009261	208	0.015
germ cell development	GO:0007281	185	0.015
regulation of cellular ketone metabolic process	GO:0010565	66	0.015
regulation of translation	GO:0006417	71	0.015
lymphocyte differentiation	GO:0030098	242	0.015
purine containing compound catabolic process	GO:0072523	213	0.015
regulation of nucleoside metabolic process	GO:0009118	130	0.015
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.015
regulation of muscle tissue development	GO:1901861	97	0.015
regulation of mrna splicing via spliceosome	GO:0048024	32	0.014
actomyosin structure organization	GO:0031032	56	0.014
leukocyte differentiation	GO:0002521	342	0.014
dendrite development	GO:0016358	115	0.014
tube closure	GO:0060606	91	0.014
glycosyl compound metabolic process	GO:1901657	246	0.014
regulation of system process	GO:0044057	200	0.014
purine nucleotide catabolic process	GO:0006195	211	0.014
regulation of cell adhesion	GO:0030155	154	0.014
regulation of protein localization	GO:0032880	231	0.013
regulation of hydrolase activity	GO:0051336	246	0.013
cellular ketone metabolic process	GO:0042180	84	0.013
regulation of transferase activity	GO:0051338	263	0.013
muscle cell development	GO:0055001	133	0.013
mitotic nuclear division	GO:0007067	48	0.013
heart morphogenesis	GO:0003007	178	0.013
carbohydrate derivative catabolic process	GO:1901136	231	0.013
nucleoside catabolic process	GO:0009164	206	0.013
camera type eye development	GO:0043010	266	0.013
regulation of purine nucleotide catabolic process	GO:0033121	122	0.013
regulation of ras protein signal transduction	GO:0046578	114	0.012
cellular protein catabolic process	GO:0044257	155	0.012
nucleoside metabolic process	GO:0009116	246	0.012
nucleobase containing small molecule metabolic process	GO:0055086	352	0.012
organelle localization	GO:0051640	179	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.012
positive regulation of cellular amine metabolic process	GO:0033240	5	0.012
epithelial cell proliferation	GO:0050673	174	0.012
transmembrane transport	GO:0055085	412	0.012
macromolecule catabolic process	GO:0009057	281	0.012	Human
fertilization	GO:0009566	127	0.012
cellular amine metabolic process	GO:0044106	44	0.012
rna 5 end processing	GO:0000966	1	0.012
negative regulation of intracellular signal transduction	GO:1902532	167	0.012
cellular response to lipid	GO:0071396	145	0.012
modification dependent macromolecule catabolic process	GO:0043632	133	0.011
ribose phosphate metabolic process	GO:0019693	291	0.011
regulation of protein stability	GO:0031647	52	0.011
purine nucleotide metabolic process	GO:0006163	302	0.011
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.011
cation transmembrane transport	GO:0098655	266	0.011
ion transmembrane transport	GO:0034220	361	0.011
muscle fiber development	GO:0048747	76	0.011
regulation of ras gtpase activity	GO:0032318	88	0.011
regulation of mrna processing	GO:0050684	41	0.011
gonad development	GO:0008406	141	0.011
aromatic compound catabolic process	GO:0019439	286	0.011	Human
regulation of binding	GO:0051098	111	0.011
cellular response to organic cyclic compound	GO:0071407	87	0.011
transmission of nerve impulse	GO:0019226	76	0.011
glycosyl compound catabolic process	GO:1901658	206	0.011
cognition	GO:0050890	149	0.011
lipid localization	GO:0010876	126	0.011
spindle organization	GO:0007051	28	0.011
amine metabolic process	GO:0009308	45	0.010
positive regulation of nucleotide catabolic process	GO:0030813	88	0.010
muscle cell differentiation	GO:0042692	261	0.010
regulation of peptidase activity	GO:0052547	96	0.010
mapk cascade	GO:0000165	281	0.010
regulation of translational initiation	GO:0006446	15	0.010
regulation of cell migration	GO:0030334	219	0.010
blood vessel morphogenesis	GO:0048514	285	0.010
cellularization	GO:0007349	1	0.010

Eif3e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.041
nervous system disease	DOID:863	0.041
central nervous system disease	DOID:331	0.013
neurodegenerative disease	DOID:1289	0.013

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