Mus musculus

12 known processes

Fh1

fumarate hydratase 1

(Aliases: Fh,Fh-1)

Fh1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular respirationGO:0045333380.917
Yeast
oxidation reduction processGO:00551143420.900
Yeast
generation of precursor metabolites and energyGO:00060911030.886
Yeast
citrate metabolic processGO:000610130.797
energy derivation by oxidation of organic compoundsGO:0015980770.769
Yeast
nucleoside phosphate metabolic processGO:00067533380.636
nucleoside triphosphate metabolic processGO:00091412300.607
coenzyme metabolic processGO:0006732520.589
purine ribonucleotide metabolic processGO:00091502900.454
purine ribonucleoside triphosphate metabolic processGO:00092052200.428
nucleobase containing small molecule metabolic processGO:00550863520.427
purine nucleoside metabolic processGO:00422782410.401
ribose phosphate metabolic processGO:00196932910.386
nucleoside monophosphate metabolic processGO:0009123850.368
atp metabolic processGO:0046034750.360
coenzyme biosynthetic processGO:0009108230.352
nadh metabolic processGO:000673410.346
ribonucleoside metabolic processGO:00091192450.284
purine ribonucleoside monophosphate metabolic processGO:0009167800.273
ribonucleotide metabolic processGO:00092592910.271
cofactor transportGO:005118140.269
nucleoside metabolic processGO:00091162460.264
purine nucleotide metabolic processGO:00061633020.263
acyl coa metabolic processGO:0006637190.259
ribonucleoside monophosphate metabolic processGO:0009161800.257
purine ribonucleoside metabolic processGO:00461282410.254
glycosyl compound metabolic processGO:19016572460.243
purine nucleoside monophosphate metabolic processGO:0009126810.227
thioester metabolic processGO:0035383190.220
purine nucleoside triphosphate metabolic processGO:00091442260.215
nucleotide metabolic processGO:00091173320.213
succinyl coa metabolic processGO:000610410.204
oxidative phosphorylationGO:0006119140.184
cellular ketone metabolic processGO:0042180840.181
ribonucleoside triphosphate metabolic processGO:00091992200.160
purine containing compound metabolic processGO:00725213110.137
organonitrogen compound catabolic processGO:19015652640.125
ribonucleotide catabolic processGO:00092612080.115
transmembrane transportGO:00550854120.111
intrinsic apoptotic signaling pathwayGO:00971931320.101
mitochondrial atp synthesis coupled electron transportGO:004277580.093
cell type specific apoptotic processGO:00972852680.086
purine nucleotide catabolic processGO:00061952110.085
regulation of membrane potentialGO:00423911920.082
acetyl coa biosynthetic process from pyruvateGO:000608630.081
positive regulation of apoptotic processGO:00430652170.080
mitochondrial electron transport nadh to ubiquinoneGO:000612040.075
mitochondrion organizationGO:00070051340.075
4 hydroxyproline metabolic processGO:001947150.074
neuron apoptotic processGO:00514021420.073
positive regulation of cell deathGO:00109422240.073
aromatic compound catabolic processGO:00194392860.072
cellular amino acid metabolic processGO:00065201030.070
amine metabolic processGO:0009308450.070
regulation of cellular catabolic processGO:00313292420.066
cofactor metabolic processGO:0051186800.064
protein maturationGO:00516041760.063
cellular nitrogen compound catabolic processGO:00442702800.061
protein oxidationGO:001815820.061
mitochondrial transportGO:0006839360.059
tricarboxylic acid metabolic processGO:007235050.053
cofactor biosynthetic processGO:0051188410.053
regulation of cellular amino acid metabolic processGO:000652150.052
regulation of nucleotide metabolic processGO:00061401690.051
nitrogen compound transportGO:00717052710.050
acetyl coa biosynthetic processGO:000608550.049
regulation of cellular ketone metabolic processGO:0010565660.048
small molecule catabolic processGO:0044282710.048
mitochondrial calcium ion homeostasisGO:005156070.047
organic cyclic compound catabolic processGO:19013612950.047
peptidyl amino acid modificationGO:00181933360.047
synaptic transmissionGO:00072683290.046
cellular amine metabolic processGO:0044106440.045
gonad developmentGO:00084061410.045
alcohol metabolic processGO:00060661160.043
heterocycle catabolic processGO:00467002800.043
action potentialGO:0001508780.042
regulation of purine nucleotide metabolic processGO:19005421690.042
anion transportGO:00068201770.042
sulfur compound metabolic processGO:00067901000.042
cation transportGO:00068123990.041
monocarboxylic acid metabolic processGO:00327871910.039
purine containing compound catabolic processGO:00725232130.039
cellular divalent inorganic cation homeostasisGO:00725031270.039
atp synthesis coupled electron transportGO:004277380.038
positive regulation of cellular amino acid metabolic processGO:004576430.037
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.037
negative regulation of phosphorylationGO:00423261660.036
acyl coa biosynthetic processGO:007161670.036
organic hydroxy compound metabolic processGO:19016152030.035
locomotory behaviorGO:00076261950.035
regulation of atp metabolic processGO:1903578170.034
proton transportGO:0015992350.033
adult behaviorGO:00305341350.032
response to molecule of bacterial originGO:00022371430.032
neural tube formationGO:00018411080.032
apoptotic signaling pathwayGO:00971903060.032
small molecule biosynthetic processGO:00442831320.032
regulation of nucleoside metabolic processGO:00091181300.031
cellular ion homeostasisGO:00068731650.031
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.030
dicarboxylic acid metabolic processGO:0043648180.030
Yeast
regulation of reactive oxygen species metabolic processGO:2000377400.030
positive regulation of programmed cell deathGO:00430682180.029
purine ribonucleotide catabolic processGO:00091542080.029
purine nucleoside triphosphate catabolic processGO:00091462030.029
purine nucleoside catabolic processGO:00061522050.029
positive regulation of protein modification processGO:00314012990.028
carbohydrate derivative catabolic processGO:19011362310.028
nicotinamide nucleotide metabolic processGO:0046496120.028
substantia nigra developmentGO:002176220.028
negative regulation of cell proliferationGO:00082852960.028
lipid localizationGO:00108761260.027
organic anion transportGO:00157111370.027
gland developmentGO:00487323300.027
development of primary sexual characteristicsGO:00451371430.027
organophosphate catabolic processGO:00464342320.027
myeloid cell differentiationGO:00300992330.026
regulation of organelle organizationGO:00330432890.026
metal ion homeostasisGO:00550651890.026
lipid oxidationGO:0034440290.026
positive regulation of interleukin 8 productionGO:003275720.026
positive regulation of cellular amine metabolic processGO:003324050.026
cytoplasmic transportGO:00164822340.026
negative regulation of phosphate metabolic processGO:00459361840.026
regulation of cellular amine metabolic processGO:0033238200.026
neuron deathGO:00709971540.025
carbohydrate derivative biosynthetic processGO:19011371830.025
nucleoside triphosphate catabolic processGO:00091432050.025
inorganic cation transmembrane transportGO:00986622070.025
alpha amino acid metabolic processGO:1901605590.025
response to oxygen levelsGO:0070482620.025
divalent inorganic cation homeostasisGO:00725071380.025
cation homeostasisGO:00550802120.024
quinone metabolic processGO:190166170.024
nucleoside phosphate catabolic processGO:19012922220.024
cellular lipid metabolic processGO:00442553230.024
succinate metabolic processGO:000610540.024
aldehyde catabolic processGO:004618540.023
dna metabolic processGO:00062593030.023
response to lipopolysaccharideGO:00324961280.023
heme transportGO:001588620.023
ribonucleotide biosynthetic processGO:0009260590.023
homeostasis of number of cellsGO:00488722100.023
cellular metal ion homeostasisGO:00068751510.023
striated muscle tissue developmentGO:00147062930.023
extrinsic apoptotic signaling pathwayGO:00971911260.023
ion transmembrane transportGO:00342203610.023
age dependent response to oxidative stressGO:000130630.022
regulation of endopeptidase activityGO:0052548890.022
regulation of ion transportGO:00432692150.022
lymphocyte mediated immunityGO:00024491390.022
positive regulation of purine nucleotide metabolic processGO:19005441140.022
ribonucleoside catabolic processGO:00424542060.022
regulation of defense responseGO:00313472330.022
regulation of neuron apoptotic processGO:00435231220.021
regulation of secretionGO:00510462740.021
ribose phosphate biosynthetic processGO:0046390590.021
quinone biosynthetic processGO:190166340.021
cellular modified amino acid metabolic processGO:0006575630.021
regulation of transmembrane transportGO:00347621280.021
regulation of hormone levelsGO:00108172110.021
organonitrogen compound biosynthetic processGO:19015661920.021
regulation of hydrolase activityGO:00513362460.021
protein oligomerizationGO:0051259670.021
natural killer cell mediated cytotoxicityGO:0042267290.021
calcium ion homeostasisGO:00550741270.021
nucleoside catabolic processGO:00091642060.020
regulation of cysteine type endopeptidase activityGO:2000116650.020
negative regulation of transferase activityGO:0051348850.020
microtubule cytoskeleton organizationGO:00002261570.020
spermatogenesisGO:00072832840.020
inflammatory responseGO:00069542440.020
peptidyl cysteine modificationGO:001819880.019
age dependent general metabolic declineGO:000757130.019
steroid metabolic processGO:00082021190.019
mitochondrial protein processingGO:003498250.019
reactive oxygen species biosynthetic processGO:190340980.019
male gamete generationGO:00482322850.019
determination of adult lifespanGO:0008340110.019
cellular response to oxidative stressGO:0034599760.019
cellular homeostasisGO:00197252400.019
negative regulation of cellular amine metabolic processGO:003323910.019
hydrogen ion transmembrane transportGO:1902600250.019
porphyrin containing compound metabolic processGO:0006778220.019
purine ribonucleoside triphosphate catabolic processGO:00092071990.019
protein processingGO:00164851630.019
negative regulation of neuron apoptotic processGO:0043524920.018
oxidoreduction coenzyme metabolic processGO:0006733160.018
neural precursor cell proliferationGO:00613511210.018
membrane organizationGO:00610242450.018
multicellular organism growthGO:00352641610.018
negative regulation of intracellular signal transductionGO:19025321670.018
cytokine productionGO:00018163190.018
aerobic respirationGO:000906070.018
Yeast
reactive oxygen species metabolic processGO:0072593840.018
regulation of cell activationGO:00508652890.018
hormone metabolic processGO:0042445860.018
cardiac muscle tissue developmentGO:00487381300.018
cation transmembrane transportGO:00986552660.018
response to organonitrogen compoundGO:00102432460.018
positive regulation of proteolysisGO:0045862850.018
removal of superoxide radicalsGO:0019430120.017
blood circulationGO:00080151950.017
positive regulation of protein kinase activityGO:00458601440.017
cellular macromolecule catabolic processGO:00442652060.017
response to oxidative stressGO:00069791230.017
regulation of neurotransmitter levelsGO:0001505870.017
dna catabolic process endonucleolyticGO:0000737150.017
muscle tissue developmentGO:00605373080.017
regulation of apoptotic signaling pathwayGO:20012331970.016
maintenance of locationGO:0051235890.016
regulation of lymphocyte activationGO:00512492400.016
epithelial tube morphogenesisGO:00605623030.016
positive regulation of hydrolase activityGO:00513451480.016
leukocyte differentiationGO:00025213420.016
purine nucleotide biosynthetic processGO:0006164650.016
regulation of neuron deathGO:19012141340.016
monoamine transportGO:0015844330.016
cellular response to biotic stimulusGO:0071216920.016
development of primary male sexual characteristicsGO:0046546880.016
regulation of transferase activityGO:00513382630.016
positive regulation of reactive oxygen species metabolic processGO:2000379110.016
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.015
positive regulation of growthGO:00459271040.015
protein localization to organelleGO:00333651850.015
positive regulation of endopeptidase activityGO:0010950430.015
epithelial cell proliferationGO:00506731740.015
embryonic epithelial tube formationGO:00018381300.015
cellular chemical homeostasisGO:00550822150.015
heart morphogenesisGO:00030071780.015
connective tissue developmentGO:00614481790.015
cellular response to lipopolysaccharideGO:0071222770.015
adult locomotory behaviorGO:0008344910.015
male sex differentiationGO:00466611090.015
regulation of atp biosynthetic processGO:200116930.015
acetyl coa metabolic processGO:000608480.015
pyridine nucleotide metabolic processGO:0019362120.015
regulation of kinase activityGO:00435492490.015
t cell activationGO:00421102890.015
cellular amino acid catabolic processGO:0009063250.014
negative regulation of neuron deathGO:1901215980.014
negative regulation of phosphorus metabolic processGO:00105631840.014
positive regulation of protein phosphorylationGO:00019342420.014
multicellular organismal homeostasisGO:00488711640.014
macromolecule catabolic processGO:00090572810.014
mitochondrial electron transport ubiquinol to cytochrome cGO:000612220.014
lipid catabolic processGO:0016042690.014
immune effector processGO:00022523210.014
organophosphate biosynthetic processGO:00904071220.014
regulation of peptidase activityGO:0052547960.014
regulation of blood pressureGO:0008217930.014
positive regulation of atp biosynthetic processGO:200117120.013
divalent metal ion transportGO:00708381720.013
multicellular organismal agingGO:0010259240.013
response to oxygen radicalGO:0000305160.013
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.013
morphogenesis of embryonic epitheliumGO:00163311590.013
lateral inhibitionGO:004633110.013
cellular response to superoxideGO:0071451140.013
regulation of mitochondrial membrane potentialGO:0051881170.013
regulation of response to woundingGO:19030341890.013
response to superoxideGO:0000303160.013
negative regulation of molecular functionGO:00440922580.013
regulation of secretion by cellGO:19035302490.012
protein acylationGO:0043543640.012
regulation of wound healingGO:0061041400.012
cellular response to molecule of bacterial originGO:0071219830.012
regulation of cytokine productionGO:00018172660.012
hepaticobiliary system developmentGO:0061008670.012
interleukin 8 productionGO:003263740.012
inorganic ion transmembrane transportGO:00986602340.012
negative regulation of protein metabolic processGO:00512482820.012
synaptic vesicle transportGO:0048489570.012
atp catabolic processGO:0006200550.012
negative regulation of eosinophil degranulationGO:004331010.012
regulation of transporter activityGO:0032409570.012
cellular response to oxygen radicalGO:0071450140.012
organic hydroxy compound transportGO:0015850930.012
anatomical structure homeostasisGO:00602491450.012
covalent chromatin modificationGO:00165691630.012
vesicle localizationGO:0051648860.012
cellular response to lipidGO:00713961450.012
microtubule based processGO:00070172360.011
organic hydroxy compound biosynthetic processGO:1901617770.011
regulation of cellular response to stressGO:00801351590.011
nucleotide biosynthetic processGO:0009165780.011
neural tube developmentGO:00219151600.011
innate immune responseGO:00450871570.011
positive regulation of nervous system developmentGO:00519622210.011
pigment biosynthetic processGO:0046148260.011
regulation of oxidative phosphorylation uncoupler activityGO:200027530.011
regulation of proteolysisGO:00301621640.011
apoptotic nuclear changesGO:003026290.011
divalent inorganic cation transportGO:00725111780.011
regulation of removal of superoxide radicalsGO:200012140.011
purine ribonucleoside biosynthetic processGO:0046129190.011
sulfur compound biosynthetic processGO:0044272370.011
diterpenoid metabolic processGO:0016101240.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
establishment of vesicle localizationGO:0051650810.011
myeloid cell homeostasisGO:00022621140.011
regulation of interleukin 8 productionGO:003267730.011
response to organic cyclic compoundGO:00140701980.011
endocytosisGO:00068971680.011
purine containing compound biosynthetic processGO:0072522700.011
fatty acid metabolic processGO:00066311210.011
ketone catabolic processGO:004218230.011
male gonad developmentGO:0008584880.011
pyridine containing compound metabolic processGO:0072524140.010
nucleoside phosphate biosynthetic processGO:1901293790.010
negative regulation of cellular protein metabolic processGO:00322692470.010
glycosyl compound catabolic processGO:19016582060.010
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.010
regulation of establishment of protein localizationGO:00702011810.010
nucleotide catabolic processGO:00091662170.010
positive regulation of organelle organizationGO:00106381280.010
positive regulation of nucleotide metabolic processGO:00459811140.010

Fh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.131
inherited metabolic disorderDOID:65500.131
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.036
disease of cellular proliferationDOID:1456600.034
cancerDOID:16200.021
central nervous system diseaseDOID:33100.021
organ system cancerDOID:005068600.015
neurodegenerative diseaseDOID:128900.013
eye and adnexa diseaseDOID:149200.013
eye diseaseDOID:561400.013
sensory system diseaseDOID:005015500.013