IMP: Integrative Multi-species Prediction

Mus musculus

132 known processes

Foxl2

forkhead box L2

(Aliases: BPES,PINTO,AU045128,Pfrk)

Ensembl: ENSMUSG00000050397
Entrez: 26927
UniProtKB: Q2TVT7
UniProtKB: O88470

Process Predictions
Disease Predictions

Foxl2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
skeletal system development	GO:0001501	356	0.578	Mouse
spinal cord development	GO:0021510	81	0.540
bmp signaling pathway	GO:0030509	93	0.525	Mouse
regionalization	GO:0003002	337	0.499	Mouse
central nervous system neuron differentiation	GO:0021953	162	0.453	Mouse
ureteric bud development	GO:0001657	94	0.448	Mouse
forebrain development	GO:0030900	302	0.381	Mouse
cell differentiation in spinal cord	GO:0021515	53	0.363
connective tissue development	GO:0061448	179	0.356	Mouse
embryonic organ morphogenesis	GO:0048562	276	0.333
paraxial mesodermal cell fate commitment	GO:0048343	2	0.327	Mouse
stem cell differentiation	GO:0048863	268	0.323	Mouse
developmental maturation	GO:0021700	193	0.301	Mouse
paraxial mesodermal cell differentiation	GO:0048342	2	0.296	Mouse
striated muscle tissue development	GO:0014706	293	0.284	Human Mouse
negative regulation of cell proliferation	GO:0008285	296	0.271
muscle tissue development	GO:0060537	308	0.246	Human Mouse
nephron development	GO:0072006	109	0.236	Mouse
mesonephros development	GO:0001823	97	0.235	Mouse
cell fate commitment	GO:0045165	210	0.227	Mouse
regulation of bmp signaling pathway	GO:0030510	60	0.217	Mouse
development of primary female sexual characteristics	GO:0046545	73	0.213
skeletal muscle cell differentiation	GO:0035914	66	0.210
somatotropin secreting cell differentiation	GO:0060126	4	0.198
kidney development	GO:0001822	213	0.197	Mouse
respiratory system development	GO:0060541	190	0.196	Mouse
epithelial tube morphogenesis	GO:0060562	303	0.190	Mouse
placenta development	GO:0001890	140	0.186	Mouse
cellular amino acid metabolic process	GO:0006520	103	0.185	Mouse
regulation of canonical wnt signaling pathway	GO:0060828	82	0.185
kidney epithelium development	GO:0072073	121	0.182	Mouse
carbon catabolite repression of transcription from rna polymerase ii promoter	GO:0000437	1	0.182	Mouse
heart morphogenesis	GO:0003007	178	0.180	Mouse
skeletal system morphogenesis	GO:0048705	203	0.172	Mouse
cartilage development	GO:0051216	140	0.171
wnt signaling pathway	GO:0016055	188	0.164
ectoderm formation	GO:0001705	3	0.160	Mouse
stem cell maintenance	GO:0019827	130	0.153
blood vessel morphogenesis	GO:0048514	285	0.145	Mouse
negative regulation of wnt signaling pathway	GO:0030178	73	0.145
ureteric bud morphogenesis	GO:0060675	62	0.144	Mouse
carbon catabolite activation of transcription	GO:0045991	4	0.143	Mouse
canonical wnt signaling pathway	GO:0060070	130	0.142
sensory system development	GO:0048880	3	0.140
regulation of neuron death	GO:1901214	134	0.139
gonad development	GO:0008406	141	0.130
appendage development	GO:0048736	166	0.129
ventral spinal cord interneuron differentiation	GO:0021514	16	0.128
regulation of wnt signaling pathway	GO:0030111	123	0.126
cell fate specification	GO:0001708	72	0.125	Mouse
female sex differentiation	GO:0046660	84	0.123
appendage morphogenesis	GO:0035107	149	0.120
regulation of organ morphogenesis	GO:2000027	144	0.119	Mouse
organ growth	GO:0035265	117	0.117	Mouse
stem cell proliferation	GO:0072089	117	0.116	Mouse
renal system development	GO:0072001	225	0.115	Mouse
nephron tubule morphogenesis	GO:0072078	68	0.115	Mouse
gland development	GO:0048732	330	0.113	Mouse
cerebral cortex development	GO:0021987	86	0.113	Mouse
chondrocyte differentiation	GO:0002062	72	0.112
nephron epithelium development	GO:0072009	92	0.112	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	5	0.112
neural precursor cell proliferation	GO:0061351	121	0.111	Mouse
cell adhesion	GO:0007155	329	0.111	Mouse
hindbrain development	GO:0030902	128	0.109	Mouse
pyramidal neuron migration	GO:0021852	1	0.107	Mouse
cervix development	GO:0060067	2	0.106
development of primary male sexual characteristics	GO:0046546	88	0.105
extracellular structure organization	GO:0043062	148	0.102	Mouse
cell type specific apoptotic process	GO:0097285	268	0.101
segmentation	GO:0035282	93	0.101	Mouse
female gonad development	GO:0008585	71	0.100
neuron projection guidance	GO:0097485	141	0.099	Mouse
ossification	GO:0001503	216	0.099	Mouse
hindbrain formation	GO:0021576	1	0.099
amine metabolic process	GO:0009308	45	0.099
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.098	Mouse
endocrine system development	GO:0035270	98	0.098	Mouse
camera type eye development	GO:0043010	266	0.097	Human Mouse
cerebellum development	GO:0021549	77	0.096
regulation of secretion	GO:0051046	274	0.095	Mouse
developmental growth involved in morphogenesis	GO:0060560	138	0.095
branching morphogenesis of an epithelial tube	GO:0048754	159	0.094	Mouse
embryonic skeletal system development	GO:0048706	120	0.094	Mouse
sensory organ morphogenesis	GO:0090596	242	0.094
epithelial cell development	GO:0002064	159	0.093	Mouse
development of primary sexual characteristics	GO:0045137	143	0.091
cerebellum formation	GO:0021588	1	0.091
ventral spinal cord development	GO:0021517	48	0.089
interleukin 8 production	GO:0032637	4	0.089
forebrain regionalization	GO:0021871	25	0.088
cellular response to growth factor stimulus	GO:0071363	197	0.088
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.086
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000079	1	0.086
neurohypophysis development	GO:0021985	2	0.085
respiratory tube development	GO:0030323	167	0.084	Mouse
negative regulation of cell development	GO:0010721	169	0.084	Mouse
metanephros development	GO:0001656	79	0.083	Mouse
cell proliferation in forebrain	GO:0021846	30	0.082
regulation of vasculature development	GO:1901342	88	0.081	Mouse
epithelial mesenchymal signaling involved in prostate gland development	GO:0060738	2	0.080	Mouse
wound healing	GO:0042060	157	0.080	Mouse
neuron death	GO:0070997	154	0.080
morphogenesis of a branching structure	GO:0001763	203	0.080	Mouse
metanephric loop of henle development	GO:0072236	4	0.079
male gonad development	GO:0008584	88	0.079
digestive tract morphogenesis	GO:0048546	147	0.078	Mouse
kidney morphogenesis	GO:0060993	83	0.078	Mouse
axonogenesis	GO:0007409	274	0.078	Mouse
spinal cord dorsal ventral patterning	GO:0021513	23	0.077
germ cell development	GO:0007281	185	0.077
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.077	Mouse
synapse organization	GO:0050808	125	0.076
regulation of lymphocyte activation	GO:0051249	240	0.076
positive regulation of nervous system development	GO:0051962	221	0.076	Mouse
pancreatic pp cell differentiation	GO:0003312	2	0.075
metencephalon development	GO:0022037	89	0.074
globus pallidus development	GO:0021759	2	0.074
negative regulation of canonical wnt signaling pathway	GO:0090090	51	0.074
hair follicle development	GO:0001942	85	0.073	Mouse
male sex differentiation	GO:0046661	109	0.072
lung development	GO:0030324	164	0.072	Mouse
regulation of cell activation	GO:0050865	289	0.072
neuron migration	GO:0001764	122	0.072	Mouse
ovarian follicle development	GO:0001541	40	0.072
forebrain morphogenesis	GO:0048853	17	0.071
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.071	Mouse
limbic system development	GO:0021761	72	0.071
granulosa cell differentiation	GO:0060014	1	0.071
regulation of cellular amine metabolic process	GO:0033238	20	0.071
regulation of anagen	GO:0051884	1	0.070
cell differentiation in hindbrain	GO:0021533	24	0.070	Mouse
axon guidance	GO:0007411	141	0.069	Mouse
leukocyte differentiation	GO:0002521	342	0.069
neural tube formation	GO:0001841	108	0.069
positive regulation of transcription from rna polymerase ii promoter by glucose	GO:0000432	3	0.068	Mouse
digestive tract development	GO:0048565	190	0.068	Mouse
outer medullary collecting duct development	GO:0072060	1	0.068
male gamete generation	GO:0048232	285	0.067	Mouse
nephron morphogenesis	GO:0072028	69	0.067	Mouse
lateral line system development	GO:0048925	1	0.067
sulfur compound metabolic process	GO:0006790	100	0.067
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation	GO:0044343	1	0.067
dorsal ventral neural tube patterning	GO:0021904	28	0.066	Mouse
negative regulation of bmp signaling pathway	GO:0030514	35	0.066
paramesonephric duct development	GO:0061205	3	0.066
embryonic epithelial tube formation	GO:0001838	130	0.065
neural tube development	GO:0021915	160	0.065	Mouse
cell maturation	GO:0048469	127	0.064	Mouse
b cell activation	GO:0042113	161	0.064
pallium development	GO:0021543	120	0.064	Mouse
regulation of cytokine production	GO:0001817	266	0.064
regulation of neuron apoptotic process	GO:0043523	122	0.064
somatic stem cell maintenance	GO:0035019	47	0.063
regulation of cell adhesion	GO:0030155	154	0.063	Mouse
cardiac chamber morphogenesis	GO:0003206	93	0.063	Mouse
polarity specification of proximal distal axis	GO:0010085	2	0.063
oviduct development	GO:0060066	3	0.063
epidermis development	GO:0008544	187	0.063	Mouse
modification dependent protein catabolic process	GO:0019941	133	0.063
spinal cord motor neuron differentiation	GO:0021522	35	0.063
limb development	GO:0060173	166	0.062
olfactory lobe development	GO:0021988	32	0.062
cardiac chamber development	GO:0003205	108	0.062	Mouse
ear development	GO:0043583	200	0.062	Mouse
blood circulation	GO:0008015	195	0.062	Mouse
regulation of cell substrate adhesion	GO:0010810	73	0.062
renal outer medulla development	GO:0072054	2	0.062
mesonephric epithelium development	GO:0072163	94	0.061	Mouse
cellular amine metabolic process	GO:0044106	44	0.061
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.061	Mouse
cellular ketone metabolic process	GO:0042180	84	0.061
meiotic cell cycle	GO:0051321	122	0.061
regulation of interleukin 8 production	GO:0032677	3	0.061
positive regulation of apoptotic process	GO:0043065	217	0.061	Human
telencephalon development	GO:0021537	186	0.060	Mouse
regulation of cell migration	GO:0030334	219	0.060	Mouse
spinal cord association neuron differentiation	GO:0021527	14	0.060
tube closure	GO:0060606	91	0.060
morphogenesis of embryonic epithelium	GO:0016331	159	0.060
somitogenesis	GO:0001756	69	0.059	Mouse
pancreatic a cell fate commitment	GO:0003326	2	0.059
muscle tissue morphogenesis	GO:0060415	53	0.059	Mouse
muscle cell differentiation	GO:0042692	261	0.059
regulation of neuron differentiation	GO:0045664	281	0.059	Mouse
renal tubule development	GO:0061326	87	0.058	Mouse
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.058
cerebellar cortex development	GO:0021695	48	0.058
chemotaxis	GO:0006935	247	0.058	Mouse
somite development	GO:0061053	81	0.057	Mouse
regulation of interleukin 8 secretion	GO:2000482	2	0.056
response to growth factor	GO:0070848	198	0.056
skin development	GO:0043588	220	0.056	Mouse
mesangial cell differentiation	GO:0072007	4	0.056	Mouse
nephric duct formation	GO:0072179	4	0.056
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.056
negative regulation of immune system process	GO:0002683	209	0.055
metanephric capsule formation	GO:0072266	1	0.055	Mouse
neuroblast differentiation	GO:0014016	2	0.055
uterus morphogenesis	GO:0061038	2	0.055
midbrain hindbrain boundary maturation	GO:0021732	1	0.055
positive regulation of cell cycle	GO:0045787	92	0.055	Mouse
cardiac muscle tissue development	GO:0048738	130	0.055	Mouse
lymphocyte differentiation	GO:0030098	242	0.054
regulation of cardiac muscle cell proliferation	GO:0060043	23	0.054
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.054	Mouse
spemann organizer formation	GO:0060061	2	0.053
regulation of response to wounding	GO:1903034	189	0.053	Mouse
epithelial tube formation	GO:0072175	130	0.053
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.053
carbohydrate metabolic process	GO:0005975	230	0.053	Mouse
histone modification	GO:0016570	159	0.052
positive regulation of cell death	GO:0010942	224	0.052	Human
regulation of neuron projection development	GO:0010975	169	0.052
wnt signaling pathway involved in forebrain neuroblast division	GO:0021874	2	0.052
stem cell development	GO:0048864	219	0.052	Mouse
mesodermal cell fate commitment	GO:0001710	17	0.052	Mouse
negative regulation of transcription from rna polymerase ii promoter by glucose	GO:0000433	1	0.052	Mouse
positive regulation of programmed cell death	GO:0043068	218	0.052	Human
formation of primary germ layer	GO:0001704	77	0.052	Mouse
carbon catabolite activation of transcription from rna polymerase ii promoter	GO:0000436	4	0.052	Mouse
t cell differentiation	GO:0030217	174	0.052
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000081	1	0.052
metanephric capsule morphogenesis	GO:0072265	1	0.052	Mouse
epithelial cell proliferation	GO:0050673	174	0.052	Mouse
mesoderm formation	GO:0001707	62	0.052	Mouse
regulation of testosterone biosynthetic process	GO:2000224	2	0.052
aromatic compound catabolic process	GO:0019439	286	0.051	Human
spinal cord patterning	GO:0021511	25	0.051
regulation of kidney development	GO:0090183	40	0.051	Mouse
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	GO:0060528	4	0.051	Mouse
multicellular organism growth	GO:0035264	161	0.051	Mouse
nucleobase containing small molecule metabolic process	GO:0055086	352	0.051
outflow tract morphogenesis	GO:0003151	53	0.051	Mouse
neural tube patterning	GO:0021532	43	0.051	Mouse
regulation of osteoblast differentiation	GO:0045667	67	0.051
endothelial cell differentiation	GO:0045446	41	0.051
nuclear division	GO:0000280	158	0.051
somatic sex determination	GO:0018993	2	0.051
purine containing compound metabolic process	GO:0072521	311	0.051
protein maturation	GO:0051604	176	0.050
positive regulation of mesonephros development	GO:0061213	20	0.050
negative regulation of molecular function	GO:0044092	258	0.049	Mouse
spemann organizer formation at the anterior end of the primitive streak	GO:0060064	1	0.049
mesenchymal cell differentiation	GO:0048762	107	0.049	Mouse
positive regulation of interleukin 8 secretion	GO:2000484	1	0.049
glomerular mesangial cell differentiation	GO:0072008	3	0.049	Mouse
skeletal muscle organ development	GO:0060538	163	0.049	Human
regulation of voltage gated calcium channel activity	GO:1901385	4	0.049
retina development in camera type eye	GO:0060041	119	0.049
cardiac cell fate determination	GO:0060913	2	0.049
ribose phosphate metabolic process	GO:0019693	291	0.049
alpha beta t cell differentiation	GO:0046632	69	0.049
cytokine production	GO:0001816	319	0.049
hypophysis morphogenesis	GO:0048850	3	0.048
ventricular septum development	GO:0003281	42	0.048
urogenital system development	GO:0001655	261	0.048	Mouse
cerebral cortex cell migration	GO:0021795	44	0.048	Mouse
positive regulation of stem cell proliferation	GO:2000648	59	0.048	Mouse
ovulation cycle	GO:0042698	59	0.048
ventral spinal cord interneuron fate commitment	GO:0060579	14	0.048
negative regulation of apoptotic process involved in outflow tract morphogenesis	GO:1902257	2	0.048	Mouse
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.047
paraxial mesoderm morphogenesis	GO:0048340	10	0.047	Mouse
regulation of cell cycle	GO:0051726	281	0.047	Mouse
regulation of organ growth	GO:0046620	61	0.047	Mouse
embryonic limb morphogenesis	GO:0030326	126	0.047
mesenchyme morphogenesis	GO:0072132	32	0.046	Mouse
prostate gland epithelium morphogenesis	GO:0060740	31	0.046	Mouse
primary neural tube formation	GO:0014020	95	0.046
steroid metabolic process	GO:0008202	119	0.046	Mouse
morphogenesis of a branching epithelium	GO:0061138	193	0.046	Mouse
meiotic nuclear division	GO:0007126	115	0.046
embryonic digit morphogenesis	GO:0042733	56	0.046
embryonic heart tube development	GO:0035050	65	0.046	Mouse
extracellular matrix organization	GO:0030198	147	0.046	Mouse
midgut development	GO:0007494	4	0.046
prostate gland stromal morphogenesis	GO:0060741	2	0.046	Mouse
odontogenesis	GO:0042476	78	0.046
alpha amino acid metabolic process	GO:1901605	59	0.045
nephron epithelium morphogenesis	GO:0072088	68	0.045	Mouse
nucleoside phosphate metabolic process	GO:0006753	338	0.045
neural tube closure	GO:0001843	90	0.045
positive regulation of protein modification process	GO:0031401	299	0.045
forebrain generation of neurons	GO:0021872	63	0.045	Mouse
regulation of cell motility	GO:2000145	236	0.045	Mouse
pattern specification involved in metanephros development	GO:0072268	4	0.045	Mouse
regulation of protein localization	GO:0032880	231	0.045
interleukin 8 secretion	GO:0072606	3	0.045
muscle fiber development	GO:0048747	76	0.045
glycoprotein metabolic process	GO:0009100	116	0.044
inner medullary collecting duct development	GO:0072061	2	0.044
mapk cascade	GO:0000165	281	0.044
morphogenesis of a polarized epithelium	GO:0001738	37	0.044
neuroblast proliferation	GO:0007405	49	0.044	Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.044
membrane organization	GO:0061024	245	0.044
central nervous system neuron development	GO:0021954	67	0.043	Mouse
negative regulation of mesenchymal cell proliferation	GO:0072201	3	0.043
positive regulation of cell activation	GO:0050867	158	0.043
cardiac septum morphogenesis	GO:0060411	46	0.043
endothelium development	GO:0003158	45	0.043	Mouse
neuron projection extension	GO:1990138	64	0.042
negative regulation of prostatic bud formation	GO:0060686	4	0.042
angiogenesis	GO:0001525	201	0.042	Mouse
t cell activation	GO:0042110	289	0.042
cerebellum morphogenesis	GO:0021587	42	0.042
negative regulation of protein metabolic process	GO:0051248	282	0.042
regulation of muscle tissue development	GO:1901861	97	0.042
regulation of mesenchymal cell proliferation	GO:0010464	37	0.042
kidney rudiment formation	GO:0072003	3	0.042
regulation of cartilage development	GO:0061035	44	0.042
regulation of organelle organization	GO:0033043	289	0.042
organic hydroxy compound metabolic process	GO:1901615	203	0.041	Mouse
gastrulation with mouth forming second	GO:0001702	29	0.041	Mouse
dopaminergic neuron differentiation	GO:0071542	14	0.041	Mouse
uterus development	GO:0060065	16	0.041
peptidyl amino acid modification	GO:0018193	336	0.041
regulation of chemotaxis	GO:0050920	53	0.041
fat cell differentiation	GO:0045444	160	0.041
regulation of chondrocyte differentiation	GO:0032330	33	0.041
hindbrain morphogenesis	GO:0021575	46	0.040
response to radiation	GO:0009314	165	0.040
tube formation	GO:0035148	140	0.040
embryonic skeletal system morphogenesis	GO:0048704	91	0.040	Mouse
retina morphogenesis in camera type eye	GO:0060042	45	0.040
positive regulation of cell adhesion	GO:0045785	80	0.040	Mouse
spermatogenesis	GO:0007283	284	0.040	Mouse
ear morphogenesis	GO:0042471	118	0.040	Mouse
cardiocyte differentiation	GO:0035051	87	0.040
renal tubule morphogenesis	GO:0061333	72	0.040	Mouse
pancreatic pp cell fate commitment	GO:0003329	2	0.040
nephrogenic mesenchyme development	GO:0072076	3	0.039	Mouse
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.039
lateral motor column neuron migration	GO:0097477	3	0.039
nephron tubule development	GO:0072080	84	0.039	Mouse
protein modification by small protein conjugation	GO:0032446	187	0.039
androgen biosynthetic process	GO:0006702	4	0.039
regulation of stem cell proliferation	GO:0072091	78	0.039	Mouse
neural crest cell differentiation	GO:0014033	54	0.038	Mouse
diencephalon development	GO:0021536	63	0.038
notch signaling pathway	GO:0007219	71	0.038	Mouse
regulation of ketone biosynthetic process	GO:0010566	2	0.038
sperm motility	GO:0030317	47	0.038
positive regulation of mesenchymal cell proliferation	GO:0002053	33	0.038
epithalamus development	GO:0021538	2	0.038
response to transforming growth factor beta	GO:0071559	88	0.038
mesenchyme development	GO:0060485	152	0.038	Mouse
regulation of morphogenesis of a branching structure	GO:0060688	53	0.038
protein catabolic process	GO:0030163	221	0.038
lung epithelium development	GO:0060428	37	0.038	Mouse
mesoderm development	GO:0007498	100	0.037	Mouse
negative regulation of cell cycle	GO:0045786	123	0.037
positive regulation of transcription from rna polymerase iii promoter	GO:0045945	1	0.037	Mouse
plasma cell differentiation	GO:0002317	3	0.037
regulation of transforming growth factor beta2 production	GO:0032909	2	0.037
mammary gland morphogenesis	GO:0060443	54	0.037
negative regulation of testosterone biosynthetic process	GO:2000225	1	0.037
neural retina development	GO:0003407	41	0.037
testosterone biosynthetic process	GO:0061370	2	0.037
regulation of neural precursor cell proliferation	GO:2000177	70	0.037	Mouse
organelle fission	GO:0048285	170	0.037
cerebral cortex radially oriented cell migration	GO:0021799	31	0.036	Mouse
regulation of organ formation	GO:0003156	34	0.036
odontogenesis of dentin containing tooth	GO:0042475	66	0.036
epithelial cell maturation involved in prostate gland development	GO:0060743	4	0.036	Mouse
granulocyte colony stimulating factor production	GO:0071611	1	0.036
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.036
maintenance of cell number	GO:0098727	3	0.036
renal vesicle development	GO:0072087	17	0.036
mitotic cell cycle	GO:0000278	195	0.036	Mouse
positive regulation of cellular catabolic process	GO:0031331	148	0.036
establishment of organ orientation	GO:0048561	1	0.036
axis elongation involved in somitogenesis	GO:0090245	4	0.036
mammary gland duct morphogenesis	GO:0060603	38	0.036
regulation of chromosome organization	GO:0033044	83	0.036
protein ubiquitination	GO:0016567	171	0.036
negative regulation of neuron death	GO:1901215	98	0.036
visceral serous pericardium development	GO:0061032	2	0.036
epithelial to mesenchymal transition	GO:0001837	47	0.036
positive regulation of anagen	GO:0051885	1	0.036
metanephric s shaped body morphogenesis	GO:0072284	2	0.035
cardiac septum development	GO:0003279	59	0.035
modification dependent macromolecule catabolic process	GO:0043632	133	0.035
endodermal cell fate specification	GO:0001714	4	0.035
regulation of cardioblast differentiation	GO:0051890	3	0.035
olfactory bulb development	GO:0021772	30	0.035
nucleotide catabolic process	GO:0009166	217	0.035
regulation of interleukin 6 production	GO:0032675	55	0.035
positive regulation of interleukin 8 production	GO:0032757	2	0.035
carbon catabolite regulation of transcription from rna polymerase ii promoter	GO:0000429	4	0.035	Mouse
clara cell differentiation	GO:0060486	4	0.035
metanephros morphogenesis	GO:0003338	24	0.035
negative regulation of cell growth	GO:0030308	44	0.035
renal vesicle induction	GO:0072034	3	0.035
trachea cartilage morphogenesis	GO:0060535	4	0.035
regulation of secretion by cell	GO:1903530	249	0.035	Mouse
cellular response to biotic stimulus	GO:0071216	92	0.034
determination of left right symmetry	GO:0007368	80	0.034
production of molecular mediator of immune response	GO:0002440	103	0.034
somatotropin secreting cell development	GO:0060133	2	0.034
positive regulation of neural precursor cell proliferation	GO:2000179	42	0.034	Mouse
central nervous system vasculogenesis	GO:0022009	3	0.034
cellular nitrogen compound catabolic process	GO:0044270	280	0.034	Human
renal inner medulla development	GO:0072053	3	0.034
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.034
regulation of establishment of protein localization	GO:0070201	181	0.034
molting cycle	GO:0042303	90	0.034	Mouse
dna metabolic process	GO:0006259	303	0.034	Human
spinal cord oligodendrocyte cell fate specification	GO:0021530	3	0.034
regulation of mesonephros development	GO:0061217	24	0.033
bone development	GO:0060348	120	0.033
negative regulation of cellular component organization	GO:0051129	194	0.033
embryonic heart tube morphogenesis	GO:0003143	51	0.033
regulation of meiotic cell cycle	GO:0051445	34	0.033
lung morphogenesis	GO:0060425	50	0.033	Mouse
lung field specification	GO:0060424	3	0.033
positive regulation of cell development	GO:0010720	237	0.033	Mouse
regulation of cellular ketone metabolic process	GO:0010565	66	0.033
positive regulation of cellular amine metabolic process	GO:0033240	5	0.033
epithelium migration	GO:0090132	63	0.033	Mouse
midbrain hindbrain boundary maturation during brain development	GO:0022004	1	0.033
cellular response to parathyroid hormone stimulus	GO:0071374	2	0.033
dorsal spinal cord development	GO:0021516	20	0.033
chromatin modification	GO:0016568	187	0.033	Mouse
eye photoreceptor cell differentiation	GO:0001754	41	0.033
regulation of protein modification by small protein conjugation or removal	GO:1903320	57	0.033
regulation of embryonic development	GO:0045995	71	0.032	Mouse
limb morphogenesis	GO:0035108	149	0.032
regulation of cell cycle process	GO:0010564	160	0.032
cellular macromolecule catabolic process	GO:0044265	206	0.032	Human
embryonic appendage morphogenesis	GO:0035113	126	0.032
skeletal muscle fiber development	GO:0048741	58	0.032
planar cell polarity pathway involved in pericardium morphogenesis	GO:0061354	2	0.032
female somatic sex determination	GO:0019101	1	0.032
sertoli cell differentiation	GO:0060008	18	0.032
positive regulation of mesenchymal cell proliferation involved in ureter development	GO:2000729	3	0.032
gonad morphogenesis	GO:0035262	1	0.032
gastrulation	GO:0007369	116	0.032	Mouse
cellular lipid metabolic process	GO:0044255	323	0.031
neuron apoptotic process	GO:0051402	142	0.031
cation transmembrane transport	GO:0098655	266	0.031
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.031
circulatory system process	GO:0003013	197	0.031	Mouse
negative regulation of response to wounding	GO:1903035	77	0.031
cell substrate adhesion	GO:0031589	130	0.031
heart growth	GO:0060419	45	0.031	Mouse
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.031
sclerotome development	GO:0061056	4	0.031
spinal cord oligodendrocyte cell differentiation	GO:0021529	3	0.031
carbon catabolite repression of transcription	GO:0045013	1	0.030	Mouse
small molecule biosynthetic process	GO:0044283	132	0.030
mesodermal cell differentiation	GO:0048333	22	0.030	Mouse
cranial nerve development	GO:0021545	41	0.030
adenohypophysis development	GO:0021984	14	0.030
purine ribonucleotide metabolic process	GO:0009150	290	0.030
peptidyl tyrosine phosphorylation	GO:0018108	143	0.030
epithelial cell morphogenesis	GO:0003382	41	0.030
negative regulation of transforming growth factor beta receptor signaling pathway	GO:0030512	26	0.030
prostate gland morphogenesis	GO:0060512	32	0.030	Mouse
visceral motor neuron differentiation	GO:0021524	3	0.030
regulation of leukocyte differentiation	GO:1902105	159	0.030
positive regulation of angiogenesis	GO:0045766	46	0.030	Mouse
regulation of cell projection organization	GO:0031344	206	0.030
positive regulation of bmp signaling pathway	GO:0030513	23	0.030	Mouse
establishment of tissue polarity	GO:0007164	28	0.030
mesoderm morphogenesis	GO:0048332	64	0.030	Mouse
regulation of b cell activation	GO:0050864	81	0.030
brain segmentation	GO:0035284	3	0.030
lateral sprouting involved in mammary gland duct morphogenesis	GO:0060599	2	0.029
ventral spinal cord interneuron specification	GO:0021521	11	0.029
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process	GO:2000763	1	0.029
cardiac pacemaker cell fate commitment	GO:0060927	1	0.029
tongue development	GO:0043586	18	0.029
metanephric capsule development	GO:0072213	1	0.029	Mouse
pituitary gland development	GO:0021983	38	0.029
macromolecule catabolic process	GO:0009057	281	0.029	Human
palate development	GO:0060021	76	0.029
negative regulation of cellular protein metabolic process	GO:0032269	247	0.029
determination of heart left right asymmetry	GO:0061371	48	0.029
establishment or maintenance of polarity of embryonic epithelium	GO:0016332	1	0.029
oocyte differentiation	GO:0009994	35	0.029
negative regulation of neuron differentiation	GO:0045665	101	0.029	Mouse
establishment of anatomical structure orientation	GO:0048560	1	0.029
blastocyst formation	GO:0001825	33	0.029	Mouse
leukocyte apoptotic process	GO:0071887	71	0.029
forebrain neuron development	GO:0021884	30	0.029	Mouse
cellular response to external stimulus	GO:0071496	88	0.029	Mouse
prostate gland development	GO:0030850	48	0.028	Mouse
neuron fate determination	GO:0048664	9	0.028	Mouse
regulation of mitotic cell cycle	GO:0007346	126	0.028	Mouse
positive regulation of inositol phosphate biosynthetic process	GO:0060732	2	0.028
his purkinje system development	GO:0003164	4	0.028
cardiac atrium morphogenesis	GO:0003209	23	0.028

Foxl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability	Func Analog Org
sensory system disease	DOID:0050155	0.055
disease of anatomical entity	DOID:7	0.055	Human
eye and adnexa disease	DOID:1492	0.055
nervous system disease	DOID:863	0.055
eye disease	DOID:5614	0.055

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