IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Gltscr2

glioma tumor suppressor candidate region gene 2

(Aliases: AU041936,PICT-1,9430097C02Rik,AW536441,R74911,5330430H08Rik)

Entrez: 68077
Ensembl: ENSMUSG00000041560
UniProtKB: Q8BK35

Process Predictions
Disease Predictions

Gltscr2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
translational initiation	GO:0006413	24	0.277
transcription from rna polymerase iii promoter	GO:0006383	3	0.200
endoplasmic reticulum tubular network organization	GO:0071786	1	0.177
translational elongation	GO:0006414	12	0.113
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.110
peptidyl amino acid modification	GO:0018193	336	0.095
nucleoside phosphate metabolic process	GO:0006753	338	0.082
regulation of cellular amine metabolic process	GO:0033238	20	0.078
digestive tract morphogenesis	GO:0048546	147	0.074
regulation of transcription from rna polymerase iii promoter	GO:0006359	2	0.062
cellular amino acid metabolic process	GO:0006520	103	0.062
hematopoietic progenitor cell differentiation	GO:0002244	143	0.062
cellular amine metabolic process	GO:0044106	44	0.061
digestive system development	GO:0055123	200	0.060
macromolecule catabolic process	GO:0009057	281	0.057
gastrulation	GO:0007369	116	0.056
protein tetramerization	GO:0051262	23	0.055
regulation of cellular ketone metabolic process	GO:0010565	66	0.054
cytoplasmic transport	GO:0016482	234	0.052
oxidation reduction process	GO:0055114	342	0.050
cellular carbohydrate metabolic process	GO:0044262	119	0.049
posttranscriptional regulation of gene expression	GO:0010608	155	0.048
nucleotide metabolic process	GO:0009117	332	0.048
germ cell development	GO:0007281	185	0.046
cellular ketone metabolic process	GO:0042180	84	0.045
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000462	1	0.044
regulation of cellular amino acid metabolic process	GO:0006521	5	0.043
cellular homeostasis	GO:0019725	240	0.042
protein catabolic process	GO:0030163	221	0.041
amine metabolic process	GO:0009308	45	0.041
regulation of er to golgi vesicle mediated transport	GO:0060628	4	0.041
negative regulation of cellular amine metabolic process	GO:0033239	1	0.041
translation	GO:0006412	93	0.041
monocarboxylic acid metabolic process	GO:0032787	191	0.040
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.038
negative regulation of protein modification process	GO:0031400	163	0.037
negative regulation of cellular protein metabolic process	GO:0032269	247	0.036
endomembrane system organization	GO:0010256	147	0.035
neuron death	GO:0070997	154	0.035
regulation of vesicle mediated transport	GO:0060627	139	0.034
regulation of cytoplasmic transport	GO:1903649	112	0.033
endocytosis	GO:0006897	168	0.033
digestive tract development	GO:0048565	190	0.032
regulation of neuron death	GO:1901214	134	0.032
nucleobase containing small molecule metabolic process	GO:0055086	352	0.032
generation of precursor metabolites and energy	GO:0006091	103	0.032
neuronal action potential	GO:0019228	54	0.032
regulation of intracellular transport	GO:0032386	159	0.031
nitrogen compound transport	GO:0071705	271	0.029
heterocycle catabolic process	GO:0046700	280	0.029
nucleoside metabolic process	GO:0009116	246	0.028
positive regulation of cellular amine metabolic process	GO:0033240	5	0.028
regulation of membrane potential	GO:0042391	192	0.028
purine nucleotide metabolic process	GO:0006163	302	0.027
glycosyl compound metabolic process	GO:1901657	246	0.027
plasma membrane organization	GO:0007009	90	0.026
rna processing	GO:0006396	105	0.026
mitotic cell cycle	GO:0000278	195	0.026
mitotic cell cycle process	GO:1903047	159	0.026
purine ribonucleotide metabolic process	GO:0009150	290	0.026
purine containing compound catabolic process	GO:0072523	213	0.025
regulation of system process	GO:0044057	200	0.025
transmission of nerve impulse	GO:0019226	76	0.025
cellular response to lipid	GO:0071396	145	0.024
regulation of inflammatory response	GO:0050727	147	0.024
chemotaxis	GO:0006935	247	0.024
placenta development	GO:0001890	140	0.023
glucose homeostasis	GO:0042593	128	0.023
carbohydrate derivative catabolic process	GO:1901136	231	0.022
ribonucleotide metabolic process	GO:0009259	291	0.022
positive regulation of cell adhesion	GO:0045785	80	0.022
gonad development	GO:0008406	141	0.021
purine nucleoside catabolic process	GO:0006152	205	0.021
regulation of hormone levels	GO:0010817	211	0.021
purine ribonucleoside metabolic process	GO:0046128	241	0.021
purine containing compound metabolic process	GO:0072521	311	0.021
organic cyclic compound catabolic process	GO:1901361	295	0.021
mitotic spindle organization	GO:0007052	10	0.021
cell type specific apoptotic process	GO:0097285	268	0.021
oogenesis	GO:0048477	56	0.020
cellular response to cytokine stimulus	GO:0071345	189	0.020
locomotory behavior	GO:0007626	195	0.020
maturation of ssu rrna	GO:0030490	1	0.020
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.020
negative regulation of molecular function	GO:0044092	258	0.019
response to molecule of bacterial origin	GO:0002237	143	0.019
stem cell differentiation	GO:0048863	268	0.019
ensheathment of neurons	GO:0007272	76	0.019
cellular response to dna damage stimulus	GO:0006974	207	0.019
cellular nitrogen compound catabolic process	GO:0044270	280	0.019
nucleoside phosphate catabolic process	GO:1901292	222	0.019
leukocyte differentiation	GO:0002521	342	0.019
ribose phosphate metabolic process	GO:0019693	291	0.018
nucleoside catabolic process	GO:0009164	206	0.018
regulation of translation	GO:0006417	71	0.018
action potential	GO:0001508	78	0.018
response to lipopolysaccharide	GO:0032496	128	0.018
receptor mediated endocytosis	GO:0006898	51	0.018
homeostasis of number of cells	GO:0048872	210	0.018
regulation of cell motility	GO:2000145	236	0.018
protein oligomerization	GO:0051259	67	0.018
energy derivation by oxidation of organic compounds	GO:0015980	77	0.018
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.018
anatomical structure homeostasis	GO:0060249	145	0.017
regulation of cellular protein catabolic process	GO:1903362	61	0.017
multicellular organismal signaling	GO:0035637	91	0.017
regulation of protein catabolic process	GO:0042176	108	0.017
regulation of protein kinase activity	GO:0045859	232	0.017
carbohydrate homeostasis	GO:0033500	128	0.017
axon ensheathment	GO:0008366	76	0.017
intrinsic apoptotic signaling pathway	GO:0097193	132	0.017
myelination	GO:0042552	74	0.017
mapk cascade	GO:0000165	281	0.017
molting cycle	GO:0042303	90	0.016
organonitrogen compound catabolic process	GO:1901565	264	0.016
cell adhesion	GO:0007155	329	0.016
multi multicellular organism process	GO:0044706	109	0.016
regulation of hydrolase activity	GO:0051336	246	0.016
peptidyl tyrosine phosphorylation	GO:0018108	143	0.016
wnt signaling pathway	GO:0016055	188	0.015
nucleoside triphosphate catabolic process	GO:0009143	205	0.015
regulation of response to wounding	GO:1903034	189	0.015
monosaccharide metabolic process	GO:0005996	106	0.015
purine nucleoside metabolic process	GO:0042278	241	0.015
regulation of apoptotic signaling pathway	GO:2001233	197	0.015
negative regulation of defense response	GO:0031348	77	0.015
ribonucleoside metabolic process	GO:0009119	245	0.015
cation transport	GO:0006812	399	0.015
rna transport	GO:0050658	18	0.015
negative regulation of phosphate metabolic process	GO:0045936	184	0.015
striated muscle tissue development	GO:0014706	293	0.015
negative regulation of phosphorylation	GO:0042326	166	0.014
negative regulation of protein phosphorylation	GO:0001933	126	0.014
antimicrobial peptide biosynthetic process	GO:0002777	2	0.014
angiogenesis	GO:0001525	201	0.014
rhythmic process	GO:0048511	174	0.014
ossification	GO:0001503	216	0.014
nucleoside triphosphate metabolic process	GO:0009141	230	0.014
regionalization	GO:0003002	337	0.014
cytokine production	GO:0001816	319	0.014
regulation of homeostatic process	GO:0032844	182	0.013
muscle tissue development	GO:0060537	308	0.013
apoptotic signaling pathway	GO:0097190	306	0.013
response to extracellular stimulus	GO:0009991	127	0.013
cardiac chamber morphogenesis	GO:0003206	93	0.013
negative regulation of neuron apoptotic process	GO:0043524	92	0.013
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.013
g protein coupled receptor signaling pathway	GO:0007186	243	0.013
inflammatory response	GO:0006954	244	0.013
peptidyl tyrosine modification	GO:0018212	145	0.013
positive regulation of protein modification process	GO:0031401	299	0.013
purine ribonucleoside catabolic process	GO:0046130	205	0.013
negative regulation of inflammatory response	GO:0050728	61	0.013
response to monosaccharide	GO:0034284	67	0.013
response to light stimulus	GO:0009416	135	0.013
dephosphorylation	GO:0016311	129	0.013
ribonucleoprotein complex subunit organization	GO:0071826	28	0.012
regulation of kinase activity	GO:0043549	249	0.012
blastocyst development	GO:0001824	80	0.012
somatic stem cell maintenance	GO:0035019	47	0.012
leukocyte proliferation	GO:0070661	172	0.012
vacuolar transport	GO:0007034	11	0.012
response to radiation	GO:0009314	165	0.012
regulation of purine nucleotide metabolic process	GO:1900542	169	0.012
regulation of cell migration	GO:0030334	219	0.012
hexose metabolic process	GO:0019318	98	0.012
ribonucleoside catabolic process	GO:0042454	206	0.011
negative regulation of protein metabolic process	GO:0051248	282	0.011
regulation of cellular response to stress	GO:0080135	159	0.011
positive regulation of cell death	GO:0010942	224	0.011
intracellular receptor signaling pathway	GO:0030522	74	0.011
immune effector process	GO:0002252	321	0.011
muscle cell differentiation	GO:0042692	261	0.011
cellular response to oxidative stress	GO:0034599	76	0.011
protein maturation	GO:0051604	176	0.011
response to oxidative stress	GO:0006979	123	0.011
reactive oxygen species metabolic process	GO:0072593	84	0.011
positive regulation of cytokine production	GO:0001819	174	0.011
lymphocyte differentiation	GO:0030098	242	0.011
negative regulation of neuron death	GO:1901215	98	0.011
regulation of anatomical structure size	GO:0090066	178	0.011
protein localization to plasma membrane	GO:0072659	57	0.011
nuclear division	GO:0000280	158	0.011
positive regulation of protein homooligomerization	GO:0032464	3	0.011
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.011
microtubule based process	GO:0007017	236	0.011
organophosphate biosynthetic process	GO:0090407	122	0.011
alpha amino acid metabolic process	GO:1901605	59	0.010
carbohydrate biosynthetic process	GO:0016051	74	0.010
histone modification	GO:0016570	159	0.010
lymphocyte proliferation	GO:0046651	164	0.010
organelle fission	GO:0048285	170	0.010
negative regulation of proteolysis	GO:0045861	74	0.010
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.010
regulation of cell cycle	GO:0051726	281	0.010
innate immune response	GO:0045087	157	0.010
positive regulation of immune effector process	GO:0002699	107	0.010
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.010
cellular response to biotic stimulus	GO:0071216	92	0.010
polysaccharide metabolic process	GO:0005976	39	0.010
regulation of transferase activity	GO:0051338	263	0.010
ribonucleotide catabolic process	GO:0009261	208	0.010
gtp metabolic process	GO:0046039	144	0.010
blood vessel morphogenesis	GO:0048514	285	0.010
female gamete generation	GO:0007292	74	0.010
t cell activation	GO:0042110	289	0.010

Gltscr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
immune system disease	DOID:2914	0.026
disease of anatomical entity	DOID:7	0.026
hematopoietic system disease	DOID:74	0.026
disease of metabolism	DOID:0014667	0.018
inherited metabolic disorder	DOID:655	0.018
anemia	DOID:2355	0.015

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