IMP: Integrative Multi-species Prediction

Mus musculus

61 known processes

Gnb2l1

guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1

(Aliases: Gnb2-rs1,p205,GB-like,AL033335,Rack1)

Ensembl: ENSMUSG00000020372
Entrez: 14694
UniProtKB: P68040

Process Predictions
Disease Predictions

Gnb2l1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
translation	GO:0006412	93	0.875	Yeast Rat
translational initiation	GO:0006413	24	0.814
translational elongation	GO:0006414	12	0.789
nucleobase containing compound transport	GO:0015931	27	0.688
cellular response to interleukin 4	GO:0071353	21	0.641
ribonucleoprotein complex subunit organization	GO:0071826	28	0.449
cellular response to cytokine stimulus	GO:0071345	189	0.350
regulation of translational elongation	GO:0006448	4	0.315
microtubule based process	GO:0007017	236	0.287
nucleoside triphosphate metabolic process	GO:0009141	230	0.212	Human Yeast
ribosome biogenesis	GO:0042254	20	0.211
rna localization	GO:0006403	23	0.188
nucleocytoplasmic transport	GO:0006913	139	0.117
regulation of transferase activity	GO:0051338	263	0.110	Human
nuclear transport	GO:0051169	139	0.090
nucleobase containing small molecule metabolic process	GO:0055086	352	0.088	Human Yeast
cytoplasmic translation	GO:0002181	7	0.088
cellular protein catabolic process	GO:0044257	155	0.083	Human
purine containing compound catabolic process	GO:0072523	213	0.082	Human Yeast
ribosomal small subunit biogenesis	GO:0042274	4	0.082
cytoplasmic transport	GO:0016482	234	0.080
gonad development	GO:0008406	141	0.080
organophosphate catabolic process	GO:0046434	232	0.071	Human Yeast
nuclear export	GO:0051168	34	0.070
glycosyl compound metabolic process	GO:1901657	246	0.070	Human Yeast
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.066	Human Yeast
posttranscriptional regulation of gene expression	GO:0010608	155	0.064	Yeast Rat
ribonucleotide metabolic process	GO:0009259	291	0.064	Human Yeast
regulation of protein kinase activity	GO:0045859	232	0.059	Human
apoptotic signaling pathway	GO:0097190	306	0.058	Human
positive regulation of intrinsic apoptotic signaling pathway	GO:2001244	25	0.057	Human
purine nucleotide metabolic process	GO:0006163	302	0.055	Human Yeast
establishment of rna localization	GO:0051236	18	0.055
nucleic acid transport	GO:0050657	18	0.054
nitrogen compound transport	GO:0071705	271	0.052
centrosome duplication	GO:0051298	16	0.051
negative regulation of cellular protein metabolic process	GO:0032269	247	0.050	Human Yeast Rat
mitotic cell cycle	GO:0000278	195	0.048
regulation of kinase activity	GO:0043549	249	0.045	Human
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.044	Human
positive regulation of protein modification process	GO:0031401	299	0.043	Human
leukocyte differentiation	GO:0002521	342	0.041
centrosome cycle	GO:0007098	23	0.040
heterocycle catabolic process	GO:0046700	280	0.037	Human Yeast
nucleoside triphosphate catabolic process	GO:0009143	205	0.036	Human Yeast
organic cyclic compound catabolic process	GO:1901361	295	0.036	Human Yeast
glycosyl compound catabolic process	GO:1901658	206	0.035	Human Yeast
organelle assembly	GO:0070925	177	0.035
development of primary sexual characteristics	GO:0045137	143	0.034
rna export from nucleus	GO:0006405	15	0.033
ribonucleotide catabolic process	GO:0009261	208	0.033	Human Yeast
microtubule cytoskeleton organization	GO:0000226	157	0.033
rna processing	GO:0006396	105	0.032
neural tube formation	GO:0001841	108	0.032
regulation of defense response	GO:0031347	233	0.032
cell chemotaxis	GO:0060326	81	0.031
cellular nitrogen compound catabolic process	GO:0044270	280	0.031	Human Yeast
response to interleukin 4	GO:0070670	23	0.030
purine ribonucleotide catabolic process	GO:0009154	208	0.030	Human Yeast
nucleoside phosphate metabolic process	GO:0006753	338	0.029	Human Yeast
rna transport	GO:0050658	18	0.027
positive regulation of innate immune response	GO:0045089	80	0.027
cytoplasmic translational initiation	GO:0002183	3	0.027
innate immune response	GO:0045087	157	0.027
positive regulation of defense response	GO:0031349	124	0.026
nucleotide catabolic process	GO:0009166	217	0.026	Human Yeast
reactive oxygen species biosynthetic process	GO:1903409	8	0.026
pharynx development	GO:0060465	1	0.026
purine ribonucleotide metabolic process	GO:0009150	290	0.026	Human Yeast
organonitrogen compound biosynthetic process	GO:1901566	192	0.026
mitotic cell cycle process	GO:1903047	159	0.026
regulation of cellular catabolic process	GO:0031329	242	0.026	Human
protein modification by small protein conjugation	GO:0032446	187	0.025
regulation of translational fidelity	GO:0006450	2	0.025
pancreas development	GO:0031016	57	0.024
ribonucleoside metabolic process	GO:0009119	245	0.024	Human Yeast
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.024	Human Yeast
regulation of natural killer cell differentiation	GO:0032823	11	0.023
carbohydrate derivative catabolic process	GO:1901136	231	0.023	Human Yeast
positive regulation of protein phosphorylation	GO:0001934	242	0.022	Human
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.022	Human Yeast
positive regulation of cell activation	GO:0050867	158	0.022
cation homeostasis	GO:0055080	212	0.021
multicellular organism growth	GO:0035264	161	0.021
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.020	Human Yeast
multicellular organismal aging	GO:0010259	24	0.020
chromatin organization	GO:0006325	206	0.020
negative regulation of cell proliferation	GO:0008285	296	0.020
cell type specific apoptotic process	GO:0097285	268	0.020
positive regulation of cellular amine metabolic process	GO:0033240	5	0.020
regulation of intracellular transport	GO:0032386	159	0.019
regulation of translational initiation	GO:0006446	15	0.018
response to oxidative stress	GO:0006979	123	0.018
cellular response to epidermal growth factor stimulus	GO:0071364	4	0.018
regulation of response to wounding	GO:1903034	189	0.017
regulation of nuclear transcribed mrna poly a tail shortening	GO:0060211	4	0.017
regulation of membrane potential	GO:0042391	192	0.017	Human
reactive oxygen species metabolic process	GO:0072593	84	0.017
regulation of establishment of protein localization	GO:0070201	181	0.017	Rat
regulation of inflammatory response	GO:0050727	147	0.016
regulation of cell cycle	GO:0051726	281	0.016	Human
leukocyte proliferation	GO:0070661	172	0.016
response to epidermal growth factor	GO:0070849	4	0.016
purine ribonucleoside metabolic process	GO:0046128	241	0.016	Human Yeast
cellular homeostasis	GO:0019725	240	0.016	Yeast Fly
cellular ketone metabolic process	GO:0042180	84	0.016
protein oligomerization	GO:0051259	67	0.016	Human
gtp metabolic process	GO:0046039	144	0.016	Human Yeast
homeostasis of number of cells	GO:0048872	210	0.016
inflammatory response	GO:0006954	244	0.016
regulation of anatomical structure size	GO:0090066	178	0.016	Fly
nucleoside metabolic process	GO:0009116	246	0.015	Human Yeast
chromatin modification	GO:0016568	187	0.015
lymphocyte differentiation	GO:0030098	242	0.015
response to radiation	GO:0009314	165	0.015
cellular amine metabolic process	GO:0044106	44	0.015
endocytosis	GO:0006897	168	0.014	Human
transmembrane transport	GO:0055085	412	0.014
ribose phosphate metabolic process	GO:0019693	291	0.014	Human Yeast
macromolecule catabolic process	GO:0009057	281	0.014	Human
regulation of cell activation	GO:0050865	289	0.014
positive regulation of protein kinase activity	GO:0045860	144	0.014
cellular response to growth factor stimulus	GO:0071363	197	0.014
neural tube development	GO:0021915	160	0.014
cell adhesion	GO:0007155	329	0.014
epithelial cell proliferation	GO:0050673	174	0.014
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.014	Human
guanosine containing compound catabolic process	GO:1901069	144	0.014	Human Yeast
tube formation	GO:0035148	140	0.014
regulation of innate immune response	GO:0045088	91	0.014
interleukin 8 production	GO:0032637	4	0.014
hematopoietic progenitor cell differentiation	GO:0002244	143	0.014
nucleotide metabolic process	GO:0009117	332	0.013	Human Yeast
regulation of cellular amino acid metabolic process	GO:0006521	5	0.013
striated muscle cell development	GO:0055002	125	0.013
immune effector process	GO:0002252	321	0.013
myeloid dendritic cell activation	GO:0001773	25	0.013
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.013	Human Yeast
positive regulation of growth	GO:0045927	104	0.013
regulation of striated muscle cell differentiation	GO:0051153	81	0.013
cellular modified amino acid metabolic process	GO:0006575	63	0.013
regulation of protein stability	GO:0031647	52	0.013
carboxylic acid biosynthetic process	GO:0046394	86	0.013
neuron death	GO:0070997	154	0.012
ribonucleoside catabolic process	GO:0042454	206	0.012	Human Yeast
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.012
purine nucleotide catabolic process	GO:0006195	211	0.012	Human Yeast
regulation of ossification	GO:0030278	112	0.012
response to lipopolysaccharide	GO:0032496	128	0.012
regulation of interleukin 8 production	GO:0032677	3	0.012
cellular alcohol metabolic process	GO:0044107	3	0.012
regulation of myoblast differentiation	GO:0045661	29	0.012
cellular metal ion homeostasis	GO:0006875	151	0.012
alcohol metabolic process	GO:0006066	116	0.012
intrinsic apoptotic signaling pathway	GO:0097193	132	0.012	Human
epithelial tube morphogenesis	GO:0060562	303	0.012
epithelial tube formation	GO:0072175	130	0.012
stem cell differentiation	GO:0048863	268	0.012
chemotaxis	GO:0006935	247	0.012
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.011
positive regulation of cellular catabolic process	GO:0031331	148	0.011	Human
organic hydroxy compound biosynthetic process	GO:1901617	77	0.011
purine nucleoside catabolic process	GO:0006152	205	0.011	Human Yeast
morphogenesis of a branching structure	GO:0001763	203	0.011
lymphocyte proliferation	GO:0046651	164	0.011
regulation of translation	GO:0006417	71	0.011	Yeast Rat
cellular response to dna damage stimulus	GO:0006974	207	0.011
striated muscle tissue development	GO:0014706	293	0.011
calcium ion homeostasis	GO:0055074	127	0.011
i kappab kinase nf kappab signaling	GO:0007249	85	0.011
aromatic compound catabolic process	GO:0019439	286	0.011	Human Yeast
positive regulation of immune effector process	GO:0002699	107	0.011
negative regulation of immune effector process	GO:0002698	55	0.011
cation transport	GO:0006812	399	0.011
nucleoside phosphate catabolic process	GO:1901292	222	0.010	Human Yeast
regulation of vesicle mediated transport	GO:0060627	139	0.010	Human
embryonic epithelial tube formation	GO:0001838	130	0.010
purine nucleoside metabolic process	GO:0042278	241	0.010	Human Yeast
protein secretion	GO:0009306	111	0.010
respiratory system development	GO:0060541	190	0.010
regulation of ion transport	GO:0043269	215	0.010

Gnb2l1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.063
immune system disease	DOID:2914	0.063
nervous system disease	DOID:863	0.014

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