IMP: Integrative Multi-species Prediction

Mus musculus

32 known processes

Hoxb6

homeobox B6

(Aliases: Hox-2.2)

Ensembl: ENSMUSG00000000690
Entrez: 15414
UniProtKB: P09023

Process Predictions
Disease Predictions

Hoxb6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
trachea cartilage morphogenesis	GO:0060535	4	0.999	Mouse
cell cell signaling involved in mammary gland development	GO:0060764	2	0.999	Mouse
intestinal epithelial cell maturation	GO:0060574	2	0.998	Mouse
bone marrow development	GO:0048539	3	0.996	Mouse
spinal cord development	GO:0021510	81	0.995	Mouse
nephron tubule morphogenesis	GO:0072078	68	0.993	Mouse
bronchiole development	GO:0060435	3	0.991	Mouse
columnar cuboidal epithelial cell maturation	GO:0002069	4	0.987	Mouse
regionalization	GO:0003002	337	0.983
skeletal system morphogenesis	GO:0048705	203	0.982
epithelial tube morphogenesis	GO:0060562	303	0.965	Mouse
ureteric bud morphogenesis	GO:0060675	62	0.959	Mouse
mesonephric tubule morphogenesis	GO:0072171	63	0.958	Mouse
urogenital system development	GO:0001655	261	0.951	Mouse
nephron morphogenesis	GO:0072028	69	0.941	Mouse
negative regulation of myeloid cell differentiation	GO:0045638	38	0.939	Mouse
renal system development	GO:0072001	225	0.936	Mouse
nephron epithelium morphogenesis	GO:0072088	68	0.931	Mouse
regulation of mammary gland epithelial cell proliferation	GO:0033599	12	0.928	Mouse
kidney morphogenesis	GO:0060993	83	0.926	Mouse
dorsal spinal cord development	GO:0021516	20	0.926	Mouse
embryonic skeletal system development	GO:0048706	120	0.924
mesonephric tubule development	GO:0072164	94	0.921	Mouse
embryonic organ morphogenesis	GO:0048562	276	0.916
ureteric bud development	GO:0001657	94	0.892	Mouse
lung cell differentiation	GO:0060479	30	0.890	Mouse
notch signaling pathway	GO:0007219	71	0.886
morphogenesis of an epithelial sheet	GO:0002011	27	0.878	Mouse
lobar bronchus epithelium development	GO:0060481	5	0.876	Mouse
positive regulation of branching involved in ureteric bud morphogenesis	GO:0090190	18	0.848	Mouse
regulation of organ morphogenesis	GO:2000027	144	0.845	Mouse
kidney development	GO:0001822	213	0.845	Mouse
regulation of mesonephros development	GO:0061217	24	0.844	Mouse
nephron tubule development	GO:0072080	84	0.843	Mouse
subpallium neuron fate commitment	GO:0060163	2	0.829
cell differentiation in spinal cord	GO:0021515	53	0.826
positive regulation of mesonephros development	GO:0061213	20	0.824	Mouse
lung morphogenesis	GO:0060425	50	0.815	Mouse
respiratory system development	GO:0060541	190	0.804	Mouse
lung development	GO:0030324	164	0.791	Mouse
definitive hemopoiesis	GO:0060216	20	0.782	Mouse
renal tubule morphogenesis	GO:0061333	72	0.778	Mouse
embryonic epithelial tube formation	GO:0001838	130	0.777
paraxial mesodermal cell differentiation	GO:0048342	2	0.768
mammary gland lobule development	GO:0061377	22	0.763	Mouse
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.760	Mouse
columnar cuboidal epithelial cell development	GO:0002066	29	0.736	Mouse
epithelial tube formation	GO:0072175	130	0.732
nephron development	GO:0072006	109	0.726	Mouse
central nervous system neuron differentiation	GO:0021953	162	0.724
morphogenesis of a branching epithelium	GO:0061138	193	0.713	Mouse
mesenchyme development	GO:0060485	152	0.711	Mouse
lung epithelium development	GO:0060428	37	0.707	Mouse
cell fate commitment	GO:0045165	210	0.699
trachea development	GO:0060438	18	0.695	Mouse
grooming behavior	GO:0007625	16	0.694	Mouse
skeletal system development	GO:0001501	356	0.693
mesonephric epithelium development	GO:0072163	94	0.692	Mouse
regulation of epithelial cell proliferation	GO:0050678	141	0.692	Mouse
bronchus development	GO:0060433	10	0.690	Mouse
regulation of kidney development	GO:0090183	40	0.683	Mouse
epithelial tube branching involved in lung morphogenesis	GO:0060441	28	0.683	Mouse
intestinal epithelial cell development	GO:0060576	12	0.665	Mouse
adult locomotory behavior	GO:0008344	91	0.664	Mouse
regulation of branching involved in ureteric bud morphogenesis	GO:0090189	22	0.663	Mouse
mammary gland alveolus development	GO:0060749	22	0.659	Mouse
neural tube formation	GO:0001841	108	0.651
glandular epithelial cell differentiation	GO:0002067	38	0.650	Mouse
nephron epithelium development	GO:0072009	92	0.647	Mouse
stem cell division	GO:0017145	30	0.640	Mouse
endocrine system development	GO:0035270	98	0.636	Mouse
myeloid cell homeostasis	GO:0002262	114	0.635
mesonephros development	GO:0001823	97	0.627	Mouse
positive regulation of cell development	GO:0010720	237	0.623
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.615	Mouse
spleen development	GO:0048536	39	0.611	Mouse
paraxial mesodermal cell fate commitment	GO:0048343	2	0.607
spinal cord association neuron differentiation	GO:0021527	14	0.605
regulation of myeloid cell differentiation	GO:0045637	96	0.605	Mouse
renal tubule development	GO:0061326	87	0.604	Mouse
tube formation	GO:0035148	140	0.604
stem cell differentiation	GO:0048863	268	0.598	Mouse
lung associated mesenchyme development	GO:0060484	10	0.597	Mouse
appendage morphogenesis	GO:0035107	149	0.595
trachea cartilage development	GO:0060534	8	0.595	Mouse
hindbrain development	GO:0030902	128	0.595
lung secretory cell differentiation	GO:0061140	13	0.588	Mouse
mammary gland epithelium development	GO:0061180	65	0.585	Mouse
blood vessel morphogenesis	GO:0048514	285	0.582
cartilage morphogenesis	GO:0060536	11	0.575	Mouse
lung epithelial cell differentiation	GO:0060487	29	0.563	Mouse
neural tube closure	GO:0001843	90	0.561
digestive tract development	GO:0048565	190	0.554	Mouse
connective tissue development	GO:0061448	179	0.554	Mouse
ventral spinal cord development	GO:0021517	48	0.551
respiratory tube development	GO:0030323	167	0.535	Mouse
epidermis development	GO:0008544	187	0.526
morphogenesis of embryonic epithelium	GO:0016331	159	0.524
cellular ketone metabolic process	GO:0042180	84	0.515
regulation of neuron differentiation	GO:0045664	281	0.515
axonogenesis	GO:0007409	274	0.514
establishment of planar polarity involved in neural tube closure	GO:0090177	15	0.511
trachea morphogenesis	GO:0060439	8	0.510	Mouse
intestinal epithelial cell differentiation	GO:0060575	14	0.497	Mouse
mammary gland epithelial cell differentiation	GO:0060644	13	0.496	Mouse
regulation of stem cell differentiation	GO:2000736	50	0.494
gland development	GO:0048732	330	0.492	Mouse
lobar bronchus development	GO:0060482	6	0.485	Mouse
mesenchymal epithelial cell signaling	GO:0060638	9	0.483	Mouse
negative regulation of neuron differentiation	GO:0045665	101	0.482
somitogenesis	GO:0001756	69	0.480
forelimb morphogenesis	GO:0035136	40	0.478
embryonic skeletal system morphogenesis	GO:0048704	91	0.473
locomotory behavior	GO:0007626	195	0.464	Mouse
epithelial cell proliferation	GO:0050673	174	0.464	Mouse
somatic stem cell division	GO:0048103	19	0.461	Mouse
glossopharyngeal nerve morphogenesis	GO:0021615	4	0.459
determination of left right symmetry	GO:0007368	80	0.453
somite development	GO:0061053	81	0.446
positive regulation of stem cell proliferation	GO:2000648	59	0.445
wnt signaling pathway involved in forebrain neuroblast division	GO:0021874	2	0.439
bone development	GO:0060348	120	0.436	Mouse
forebrain development	GO:0030900	302	0.433
forebrain generation of neurons	GO:0021872	63	0.426
positive regulation of kidney development	GO:0090184	28	0.417	Mouse
olfactory lobe development	GO:0021988	32	0.415
respiratory system process	GO:0003016	25	0.414	Mouse
cellular amino acid metabolic process	GO:0006520	103	0.403
mesonephric duct formation	GO:0072181	2	0.396
tube closure	GO:0060606	91	0.384
leukocyte differentiation	GO:0002521	342	0.372
autonomic nervous system development	GO:0048483	43	0.365
segmentation	GO:0035282	93	0.361
epithelial cell maturation	GO:0002070	15	0.357	Mouse
neural tube development	GO:0021915	160	0.356
apoptotic process involved in development	GO:1902742	28	0.354
carbon catabolite repression of transcription from rna polymerase ii promoter	GO:0000437	1	0.353
mesoderm formation	GO:0001707	62	0.344
embryonic limb morphogenesis	GO:0030326	126	0.342
olfactory bulb interneuron differentiation	GO:0021889	12	0.335
t cell differentiation	GO:0030217	174	0.333
paraxial mesoderm morphogenesis	GO:0048340	10	0.333
regulation of neural precursor cell proliferation	GO:2000177	70	0.327
rhombomere 3 morphogenesis	GO:0021658	2	0.323
rhombomere 3 development	GO:0021569	4	0.322
kidney epithelium development	GO:0072073	121	0.322	Mouse
spinal cord motor neuron differentiation	GO:0021522	35	0.321
cell fate specification	GO:0001708	72	0.318
mesenchyme morphogenesis	GO:0072132	32	0.317
positive regulation of nervous system development	GO:0051962	221	0.316
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification	GO:0021913	4	0.314
embryonic appendage morphogenesis	GO:0035113	126	0.312
forebrain regionalization	GO:0021871	25	0.310
development of primary sexual characteristics	GO:0045137	143	0.308
nephric duct formation	GO:0072179	4	0.307
embryonic heart tube morphogenesis	GO:0003143	51	0.305
negative regulation of cell proliferation	GO:0008285	296	0.299
olfactory bulb development	GO:0021772	30	0.297
telencephalon development	GO:0021537	186	0.296
negative regulation of nervous system development	GO:0051961	156	0.296
polarity specification of proximal distal axis	GO:0010085	2	0.295
rhombomere 5 development	GO:0021571	4	0.295
bmp signaling pathway	GO:0030509	93	0.294
establishment of planar polarity	GO:0001736	28	0.292
digestive system development	GO:0055123	200	0.291	Mouse
cartilage development	GO:0051216	140	0.288	Mouse
formation of primary germ layer	GO:0001704	77	0.283
renal vesicle induction	GO:0072034	3	0.281
regulation of bmp signaling pathway	GO:0030510	60	0.281
embryonic nail plate morphogenesis	GO:0035880	3	0.280
developmental maturation	GO:0021700	193	0.279	Mouse
planar cell polarity pathway involved in ventricular septum morphogenesis	GO:0061348	2	0.279
adult behavior	GO:0030534	135	0.275	Mouse
cell division	GO:0051301	120	0.274	Mouse
mammary gland epithelial cell proliferation	GO:0033598	24	0.274	Mouse
syncytiotrophoblast cell differentiation involved in labyrinthine layer development	GO:0060715	2	0.273
outflow tract morphogenesis	GO:0003151	53	0.269
epithelial cell development	GO:0002064	159	0.267	Mouse
respiratory gaseous exchange	GO:0007585	43	0.266	Mouse
appendage development	GO:0048736	166	0.265
carbon catabolite activation of transcription from rna polymerase ii promoter	GO:0000436	4	0.265
planar cell polarity pathway involved in pericardium morphogenesis	GO:0061354	2	0.264
spinal cord motor neuron cell fate specification	GO:0021520	13	0.261
endothelium development	GO:0003158	45	0.261	Mouse
positive regulation of neuron differentiation	GO:0045666	141	0.260
male gamete generation	GO:0048232	285	0.259
limb morphogenesis	GO:0035108	149	0.259
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	GO:0061350	2	0.258
lung alveolus development	GO:0048286	45	0.256	Mouse
hindbrain morphogenesis	GO:0021575	46	0.256
planar cell polarity pathway involved in cardiac right atrium morphogenesis	GO:0061349	2	0.250
oviduct development	GO:0060066	3	0.250
tertiary branching involved in mammary gland duct morphogenesis	GO:0060748	3	0.246
angiogenesis	GO:0001525	201	0.245
cell maturation	GO:0048469	127	0.244	Mouse
negative regulation of cell development	GO:0010721	169	0.243
planar cell polarity pathway involved in outflow tract morphogenesis	GO:0061347	2	0.239
ventral spinal cord interneuron differentiation	GO:0021514	16	0.236
forebrain neuron differentiation	GO:0021879	52	0.236
negative regulation of bmp signaling pathway	GO:0030514	35	0.235
metanephros development	GO:0001656	79	0.232
midbrain hindbrain boundary maturation	GO:0021732	1	0.225
sensory organ morphogenesis	GO:0090596	242	0.225
gonad development	GO:0008406	141	0.224
axon guidance	GO:0007411	141	0.223
lung goblet cell differentiation	GO:0060480	5	0.222	Mouse
branching morphogenesis of an epithelial tube	GO:0048754	159	0.221	Mouse
regulation of cartilage development	GO:0061035	44	0.221
establishment of planar polarity of embryonic epithelium	GO:0042249	16	0.220
negative regulation of phosphate metabolic process	GO:0045936	184	0.217
negative regulation of prostatic bud formation	GO:0060686	4	0.215
morphogenesis of a polarized epithelium	GO:0001738	37	0.215
stem cell development	GO:0048864	219	0.214
lymphocyte differentiation	GO:0030098	242	0.213
brain morphogenesis	GO:0048854	32	0.213
somatic stem cell maintenance	GO:0035019	47	0.212
development of primary female sexual characteristics	GO:0046545	73	0.210
camera type eye development	GO:0043010	266	0.209
neural crest cell differentiation	GO:0014033	54	0.208
multicellular organism growth	GO:0035264	161	0.207	Mouse
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.207
neuron projection guidance	GO:0097485	141	0.206
specification of organ position	GO:0010159	3	0.204
regulation of establishment of planar polarity	GO:0090175	28	0.203
negative regulation of hepatocyte differentiation	GO:0070367	1	0.200
regulation of tube size	GO:0035150	57	0.199
nephrogenic mesenchyme development	GO:0072076	3	0.196
sensory perception	GO:0007600	245	0.194	Mouse
retinal blood vessel morphogenesis	GO:0061304	3	0.193
skin development	GO:0043588	220	0.193
osteoblast development	GO:0002076	17	0.192
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	GO:0014834	3	0.192
metencephalon development	GO:0022037	89	0.191
gastrulation	GO:0007369	116	0.191
organ induction	GO:0001759	21	0.191
segment specification	GO:0007379	15	0.191
hindlimb morphogenesis	GO:0035137	42	0.190
stem cell proliferation	GO:0072089	117	0.188
primary neural tube formation	GO:0014020	95	0.186
pituitary gland development	GO:0021983	38	0.186
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.185
muscular septum morphogenesis	GO:0003150	4	0.183
odontogenesis	GO:0042476	78	0.183
homeostasis of number of cells	GO:0048872	210	0.183
cardiac right atrium morphogenesis	GO:0003213	3	0.182
chemotaxis	GO:0006935	247	0.182
morphogenesis of a branching structure	GO:0001763	203	0.179	Mouse
regulation of stem cell proliferation	GO:0072091	78	0.179
ear morphogenesis	GO:0042471	118	0.178
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.178
progesterone secretion	GO:0042701	1	0.177
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.177
endothelial cell differentiation	GO:0045446	41	0.176	Mouse
fat cell differentiation	GO:0045444	160	0.176
embryonic eye morphogenesis	GO:0048048	29	0.174
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.173
limb development	GO:0060173	166	0.172
epithelial mesenchymal signaling involved in prostate gland development	GO:0060738	2	0.171
neuron fate specification	GO:0048665	30	0.167
renal vesicle development	GO:0072087	17	0.167
positive regulation of epithelial cell proliferation involved in lung morphogenesis	GO:0060501	3	0.165
inner ear morphogenesis	GO:0042472	101	0.163
lateral sprouting involved in mammary gland duct morphogenesis	GO:0060599	2	0.163
regulation of establishment of planar polarity involved in neural tube closure	GO:0090178	15	0.162
negative regulation of phosphorus metabolic process	GO:0010563	184	0.160
pattern specification involved in metanephros development	GO:0072268	4	0.160
regulation of chondrocyte differentiation	GO:0032330	33	0.160
regulation of organ formation	GO:0003156	34	0.160
regulation of cardiac muscle tissue development	GO:0055024	31	0.159
artery development	GO:0060840	53	0.158
endodermal cell fate specification	GO:0001714	4	0.158
wnt signaling pathway planar cell polarity pathway	GO:0060071	27	0.156
mesonephric duct morphogenesis	GO:0072180	4	0.155
response to organic cyclic compound	GO:0014070	198	0.154
spermatogenesis	GO:0007283	284	0.154
positive regulation of neuroblast proliferation	GO:0002052	19	0.152
myeloid cell differentiation	GO:0030099	233	0.152	Mouse
midbrain hindbrain boundary maturation during brain development	GO:0022004	1	0.151
mammary gland morphogenesis	GO:0060443	54	0.151
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.151
regulation of cellular amine metabolic process	GO:0033238	20	0.150
positive regulation of transcription from rna polymerase ii promoter by glucose	GO:0000432	3	0.150
pallium development	GO:0021543	120	0.149
establishment of organ orientation	GO:0048561	1	0.149
mesonephric tubule formation	GO:0072172	11	0.149
pyramidal neuron migration	GO:0021852	1	0.149
response to growth factor	GO:0070848	198	0.149
limbic system development	GO:0021761	72	0.149
erythrocyte differentiation	GO:0030218	88	0.148
central nervous system vasculogenesis	GO:0022009	3	0.148
ear development	GO:0043583	200	0.148
regulation of apoptotic process involved in morphogenesis	GO:1902337	10	0.144
wnt signaling pathway	GO:0016055	188	0.144
rhombomere development	GO:0021546	8	0.143
embryonic heart tube development	GO:0035050	65	0.143
cell adhesion	GO:0007155	329	0.143
positive regulation of secondary heart field cardioblast proliferation	GO:0072513	4	0.141
planar cell polarity pathway involved in neural tube closure	GO:0090179	14	0.140
blastocyst formation	GO:0001825	33	0.139
regulation of excretion	GO:0044062	5	0.139
regulation of anagen	GO:0051884	1	0.138
regulation of leukocyte differentiation	GO:1902105	159	0.138
central nervous system neuron development	GO:0021954	67	0.138
blastocyst development	GO:0001824	80	0.137
regulation of system process	GO:0044057	200	0.135
organelle fission	GO:0048285	170	0.134
mesodermal cell differentiation	GO:0048333	22	0.134
development of primary male sexual characteristics	GO:0046546	88	0.134
metanephric nephron development	GO:0072210	34	0.133
neural precursor cell proliferation	GO:0061351	121	0.133
developmental programmed cell death	GO:0010623	41	0.132
embryonic digit morphogenesis	GO:0042733	56	0.131
regulation of cellular ketone metabolic process	GO:0010565	66	0.131
cell differentiation in hindbrain	GO:0021533	24	0.131
metanephric renal vesicle morphogenesis	GO:0072283	12	0.130
prostate gland morphogenesis	GO:0060512	32	0.130
regulation of kinase activity	GO:0043549	249	0.129
lung induction	GO:0060492	3	0.129
midgut development	GO:0007494	4	0.127
positive regulation of ureteric bud formation	GO:0072107	3	0.127
thymus development	GO:0048538	41	0.124
spinal cord dorsal ventral patterning	GO:0021513	23	0.124
regulation of ossification	GO:0030278	112	0.124
endocrine pancreas development	GO:0031018	29	0.123
regulation of fat cell differentiation	GO:0045598	81	0.123
cardiac chamber morphogenesis	GO:0003206	93	0.122
cell proliferation involved in outflow tract morphogenesis	GO:0061325	4	0.122
mammary gland duct morphogenesis	GO:0060603	38	0.122
negative regulation of apoptotic process involved in outflow tract morphogenesis	GO:1902257	2	0.121
somite rostral caudal axis specification	GO:0032525	13	0.121
embryonic axis specification	GO:0000578	30	0.121
glial cell differentiation	GO:0010001	131	0.120
positive regulation of stem cell differentiation	GO:2000738	23	0.120
brain segmentation	GO:0035284	3	0.119
positive regulation of cardiac muscle cell proliferation	GO:0060045	15	0.118
positive regulation of cell death	GO:0010942	224	0.116
neuron migration	GO:0001764	122	0.116
regulation of cell cycle	GO:0051726	281	0.116
cellular response to growth factor stimulus	GO:0071363	197	0.115
establishment of planar polarity involved in nephron morphogenesis	GO:0072046	1	0.115
maintenance of cell number	GO:0098727	3	0.113
cerebellum vasculature morphogenesis	GO:0061301	1	0.112
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000079	1	0.112
regulation of cell adhesion	GO:0030155	154	0.109
protein modification by small protein conjugation or removal	GO:0070647	207	0.109
positive regulation of apoptotic process involved in morphogenesis	GO:1902339	4	0.109
regulation of cell migration	GO:0030334	219	0.108
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	GO:0072039	4	0.108
cardiac chamber development	GO:0003205	108	0.107
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.107
cellular amine metabolic process	GO:0044106	44	0.107
nephron tubule formation	GO:0072079	20	0.107
hematopoietic progenitor cell differentiation	GO:0002244	143	0.106
kidney rudiment formation	GO:0072003	3	0.106
negative regulation of leukocyte differentiation	GO:1902106	51	0.106
embryonic forelimb morphogenesis	GO:0035115	32	0.105
mesenchymal cell differentiation	GO:0048762	107	0.105
cardiac septum morphogenesis	GO:0060411	46	0.105
negative regulation of execution phase of apoptosis	GO:1900118	4	0.104
neural tube patterning	GO:0021532	43	0.104
negative regulation of immune system process	GO:0002683	209	0.103	Mouse
metanephric loop of henle development	GO:0072236	4	0.103
specification of organ identity	GO:0010092	30	0.103
mesodermal cell fate commitment	GO:0001710	17	0.102
axis elongation involved in somitogenesis	GO:0090245	4	0.101
ventral spinal cord interneuron fate commitment	GO:0060579	14	0.101
hair follicle development	GO:0001942	85	0.100
mesoderm development	GO:0007498	100	0.100
renal capsule morphogenesis	GO:0072128	1	0.100
skin morphogenesis	GO:0043589	38	0.100
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.100
establishment of anatomical structure orientation	GO:0048560	1	0.099
negative regulation of synapse assembly	GO:0051964	3	0.099
post anal tail morphogenesis	GO:0036342	23	0.099
ventral spinal cord interneuron specification	GO:0021521	11	0.098
ventricular septum development	GO:0003281	42	0.097
cerebral cortex development	GO:0021987	86	0.097
ossification	GO:0001503	216	0.097
oligodendrocyte differentiation	GO:0048709	53	0.096
positive regulation of lymphocyte activation	GO:0051251	140	0.095
regulation of renal sodium excretion	GO:0035813	3	0.094
cellular response to acid chemical	GO:0071229	68	0.094
endocardial cushion to mesenchymal transition involved in heart valve formation	GO:0003199	4	0.094
positive regulation of protein secretion	GO:0050714	52	0.094
inner medullary collecting duct development	GO:0072061	2	0.094
regulation of protein transport	GO:0051223	163	0.094
regulation of cellular amino acid metabolic process	GO:0006521	5	0.093
bone morphogenesis	GO:0060349	78	0.093
apoptotic signaling pathway	GO:0097190	306	0.092
cerebellum vasculature development	GO:0061300	1	0.092
striated muscle tissue development	GO:0014706	293	0.092
regulation of ureteric bud formation	GO:0072106	3	0.092
regulation of angiogenesis	GO:0045765	81	0.092
female sex determination	GO:0030237	1	0.092
heart formation	GO:0060914	16	0.092
placenta blood vessel development	GO:0060674	31	0.092
epithelial cell morphogenesis	GO:0003382	41	0.092
positive regulation of transcription initiation from rna polymerase ii promoter	GO:0060261	5	0.091
prostate gland stromal morphogenesis	GO:0060741	2	0.091
cell fate commitment involved in formation of primary germ layer	GO:0060795	26	0.090
regulation of chorionic trophoblast cell proliferation	GO:1901382	1	0.090
regulation of neuroblast proliferation	GO:1902692	27	0.090
cell type specific apoptotic process	GO:0097285	268	0.090
hepaticobiliary system development	GO:0061008	67	0.090
prostate gland epithelium morphogenesis	GO:0060740	31	0.089
embryonic placenta development	GO:0001892	98	0.088
somatic sex determination	GO:0018993	2	0.088
establishment of tissue polarity	GO:0007164	28	0.088
aortic valve morphogenesis	GO:0003180	4	0.088
carbohydrate derivative biosynthetic process	GO:1901137	183	0.087
embryonic viscerocranium morphogenesis	GO:0048703	8	0.087
astrocyte fate commitment	GO:0060018	4	0.086
hippocampus development	GO:0021766	52	0.086
positive regulation of anagen	GO:0051885	1	0.085
sensory perception of pain	GO:0019233	47	0.085	Mouse
female sex differentiation	GO:0046660	84	0.085
neural crest cell development	GO:0014032	48	0.085
cell fate commitment involved in pattern specification	GO:0060581	14	0.085
mitotic cell cycle	GO:0000278	195	0.084
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000081	1	0.084
midbrain development	GO:0030901	35	0.084
rhombomere morphogenesis	GO:0021593	2	0.084
male gonad development	GO:0008584	88	0.083
cellular response to lipid	GO:0071396	145	0.083
regulation of mesenchymal cell proliferation involved in ureter development	GO:0072199	3	0.082
spinal cord oligodendrocyte cell differentiation	GO:0021529	3	0.082
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.082
t cell activation	GO:0042110	289	0.082
protein catabolic process	GO:0030163	221	0.082
apoptotic process involved in morphogenesis	GO:0060561	25	0.081
hindbrain formation	GO:0021576	1	0.081
diencephalon development	GO:0021536	63	0.081
regulation of cardiac muscle cell proliferation	GO:0060043	23	0.081
regulation of homeostatic process	GO:0032844	182	0.080
mesangial cell differentiation	GO:0072007	4	0.080
placenta development	GO:0001890	140	0.079
b cell activation	GO:0042113	161	0.079
regulation of cellular component size	GO:0032535	121	0.079
regulation of mitotic cell cycle	GO:0007346	126	0.079
cell fate specification involved in pattern specification	GO:0060573	11	0.079
regulation of t cell activation	GO:0050863	170	0.079
renal outer medulla development	GO:0072054	2	0.078
cardiac muscle tissue growth	GO:0055017	37	0.078
negative regulation of mesenchymal cell proliferation	GO:0072201	3	0.078
negative regulation of cellular protein metabolic process	GO:0032269	247	0.078
hypophysis morphogenesis	GO:0048850	3	0.077
planar cell polarity pathway involved in heart morphogenesis	GO:0061346	3	0.077
carbon catabolite regulation of transcription from rna polymerase ii promoter	GO:0000429	4	0.077
middle ear morphogenesis	GO:0042474	23	0.076
regulation of lymphocyte proliferation	GO:0050670	117	0.076
parathyroid gland development	GO:0060017	5	0.076
lateral inhibition	GO:0046331	1	0.076
negative regulation of neuron projection development	GO:0010977	50	0.076
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation	GO:0003257	3	0.076
embryonic camera type eye development	GO:0031076	36	0.076
regulation of transcription involved in cell fate commitment	GO:0060850	15	0.076
positive regulation of cellular amine metabolic process	GO:0033240	5	0.076
amine metabolic process	GO:0009308	45	0.075
regulation of anatomical structure size	GO:0090066	178	0.075
regulation of transferase activity	GO:0051338	263	0.074
cell cell signaling involved in cell fate commitment	GO:0045168	35	0.074
facial nucleus development	GO:0021754	2	0.074
trophectodermal cell differentiation	GO:0001829	21	0.074
regulation of morphogenesis of a branching structure	GO:0060688	53	0.074	Mouse
regulation of lymphocyte activation	GO:0051249	240	0.074
cochlea development	GO:0090102	35	0.073
primitive streak formation	GO:0090009	10	0.073
inter male aggressive behavior	GO:0002121	3	0.073
liver development	GO:0001889	66	0.073
mesenchymal stem cell maintenance involved in nephron morphogenesis	GO:0072038	7	0.073
canonical wnt signaling pathway involved in regulation of cell proliferation	GO:0044340	3	0.073
positive regulation of transcription from rna polymerase iii promoter	GO:0045945	1	0.073
negative regulation of transcription from rna polymerase ii promoter by glucose	GO:0000433	1	0.072
regulation of metal ion transport	GO:0010959	106	0.072
regulation of transcription from rna polymerase iii promoter	GO:0006359	2	0.072
canonical wnt signaling pathway	GO:0060070	130	0.071
cardiac muscle cell differentiation	GO:0055007	69	0.071
positive regulation of programmed cell death	GO:0043068	218	0.070
regulation of leukocyte proliferation	GO:0070663	121	0.070
digestive tract morphogenesis	GO:0048546	147	0.070
hematopoietic stem cell proliferation	GO:0071425	13	0.070
steroid metabolic process	GO:0008202	119	0.070
paraxial mesoderm development	GO:0048339	18	0.069
negative regulation of fat cell differentiation	GO:0045599	36	0.069
positive regulation of epithelial cell proliferation	GO:0050679	68	0.068
cellular homeostasis	GO:0019725	240	0.068
sympathetic nervous system development	GO:0048485	22	0.067
mesonephric duct development	GO:0072177	5	0.067
carbon catabolite activation of transcription	GO:0045991	4	0.067
forebrain morphogenesis	GO:0048853	17	0.067
positive regulation of neural precursor cell proliferation	GO:2000179	42	0.067
rhombomere 2 development	GO:0021568	2	0.066
negative regulation of transforming growth factor beta receptor signaling pathway	GO:0030512	26	0.066
peripheral nervous system development	GO:0007422	53	0.066
regulation of testosterone biosynthetic process	GO:2000224	2	0.066
labyrinthine layer blood vessel development	GO:0060716	21	0.065
regulation of mesenchymal cell proliferation	GO:0010464	37	0.065
cell proliferation in hindbrain	GO:0021534	10	0.065
regulation of t cell differentiation	GO:0045580	83	0.065
regulation of vasculature development	GO:1901342	88	0.064

Hoxb6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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