IMP: Integrative Multi-species Prediction

Mus musculus

17 known processes

Hoxc6

homeobox C6

(Aliases: Hox-6.1,Hox-3.3)

Entrez: 15425
Ensembl: ENSMUSG00000001661
UniProtKB: Q543H4
UniProtKB: P10629
UniProtKB: B2RUB8

Process Predictions
Disease Predictions

Hoxc6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
trachea cartilage morphogenesis	GO:0060535	4	0.993	Mouse
intestinal epithelial cell maturation	GO:0060574	2	0.960	Mouse
spinal cord development	GO:0021510	81	0.943	Mouse
cell cell signaling involved in mammary gland development	GO:0060764	2	0.936	Mouse
spleen development	GO:0048536	39	0.928	Mouse
columnar cuboidal epithelial cell maturation	GO:0002069	4	0.916	Mouse
mesonephric tubule morphogenesis	GO:0072171	63	0.879	Mouse
blood vessel morphogenesis	GO:0048514	285	0.871
nephron tubule development	GO:0072080	84	0.863	Mouse
skeletal system morphogenesis	GO:0048705	203	0.859	Mouse
nephron tubule morphogenesis	GO:0072078	68	0.857	Mouse
bronchiole development	GO:0060435	3	0.841	Mouse
embryonic organ morphogenesis	GO:0048562	276	0.819	Mouse
embryonic skeletal system morphogenesis	GO:0048704	91	0.817	Mouse
lung development	GO:0030324	164	0.798	Mouse
embryonic skeletal system development	GO:0048706	120	0.791
skeletal system development	GO:0001501	356	0.785
urogenital system development	GO:0001655	261	0.765	Mouse
myeloid cell differentiation	GO:0030099	233	0.760	Mouse
respiratory system process	GO:0003016	25	0.749	Mouse
cell differentiation in spinal cord	GO:0021515	53	0.746
mesenchyme development	GO:0060485	152	0.740	Mouse
negative regulation of myeloid cell differentiation	GO:0045638	38	0.716	Mouse
nephron development	GO:0072006	109	0.712	Mouse
endocrine system development	GO:0035270	98	0.706	Mouse
branching morphogenesis of an epithelial tube	GO:0048754	159	0.690	Mouse
bmp signaling pathway	GO:0030509	93	0.678
lung epithelium development	GO:0060428	37	0.672	Mouse
ventral spinal cord development	GO:0021517	48	0.663
regionalization	GO:0003002	337	0.660
lung epithelial cell differentiation	GO:0060487	29	0.659	Mouse
lobar bronchus epithelium development	GO:0060481	5	0.630	Mouse
limb development	GO:0060173	166	0.628
neuron fate specification	GO:0048665	30	0.621
central nervous system neuron differentiation	GO:0021953	162	0.617
bone marrow development	GO:0048539	3	0.611	Mouse
kidney epithelium development	GO:0072073	121	0.610	Mouse
endothelium development	GO:0003158	45	0.606	Mouse
morphogenesis of an epithelial sheet	GO:0002011	27	0.584	Mouse
epidermis development	GO:0008544	187	0.578
regulation of mammary gland epithelial cell proliferation	GO:0033599	12	0.571	Mouse
endothelial cell differentiation	GO:0045446	41	0.564	Mouse
cartilage morphogenesis	GO:0060536	11	0.560	Mouse
axonogenesis	GO:0007409	274	0.558
mesonephric tubule development	GO:0072164	94	0.557	Mouse
renal tubule development	GO:0061326	87	0.556	Mouse
regulation of epithelial cell proliferation	GO:0050678	141	0.546	Mouse
ureteric bud development	GO:0001657	94	0.543	Mouse
embryonic appendage morphogenesis	GO:0035113	126	0.541
digestive tract development	GO:0048565	190	0.539	Mouse
cartilage development	GO:0051216	140	0.536	Mouse
gland development	GO:0048732	330	0.530	Mouse
lobar bronchus development	GO:0060482	6	0.527	Mouse
grooming behavior	GO:0007625	16	0.524	Mouse
digestive system development	GO:0055123	200	0.519	Mouse
positive regulation of programmed cell death	GO:0043068	218	0.517
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.514	Mouse
glandular epithelial cell differentiation	GO:0002067	38	0.505	Mouse
mammary gland lobule development	GO:0061377	22	0.471	Mouse
epithelial cell proliferation	GO:0050673	174	0.464	Mouse
epithelial tube branching involved in lung morphogenesis	GO:0060441	28	0.462	Mouse
positive regulation of nervous system development	GO:0051962	221	0.461
locomotory behavior	GO:0007626	195	0.457	Mouse
paraxial mesodermal cell fate commitment	GO:0048343	2	0.455
transmembrane transport	GO:0055085	412	0.452
spinal cord motor neuron cell fate specification	GO:0021520	13	0.451
nephron morphogenesis	GO:0072028	69	0.446	Mouse
muscle tissue development	GO:0060537	308	0.440
definitive hemopoiesis	GO:0060216	20	0.440	Mouse
stem cell differentiation	GO:0048863	268	0.438	Mouse
dorsal spinal cord development	GO:0021516	20	0.430	Mouse
developmental programmed cell death	GO:0010623	41	0.429
negative regulation of immune system process	GO:0002683	209	0.421	Mouse
nephron epithelium morphogenesis	GO:0072088	68	0.420	Mouse
cell fate specification	GO:0001708	72	0.410
mammary gland epithelial cell differentiation	GO:0060644	13	0.397	Mouse
appendage development	GO:0048736	166	0.393
positive regulation of cell death	GO:0010942	224	0.392
central nervous system neuron development	GO:0021954	67	0.392
renal tubule morphogenesis	GO:0061333	72	0.391	Mouse
regulation of cellular amine metabolic process	GO:0033238	20	0.381
embryonic limb morphogenesis	GO:0030326	126	0.381
spinal cord motor neuron differentiation	GO:0021522	35	0.375
regulation of organ morphogenesis	GO:2000027	144	0.373	Mouse
ureteric bud morphogenesis	GO:0060675	62	0.372	Mouse
cellular amino acid metabolic process	GO:0006520	103	0.370
somite development	GO:0061053	81	0.366
epithelial tube morphogenesis	GO:0060562	303	0.366	Mouse
formation of primary germ layer	GO:0001704	77	0.359
regulation of auditory receptor cell differentiation	GO:0045607	4	0.358
lung alveolus development	GO:0048286	45	0.357	Mouse
cell division	GO:0051301	120	0.357	Mouse
neuron projection guidance	GO:0097485	141	0.348
mesenchymal cell differentiation	GO:0048762	107	0.346
forebrain development	GO:0030900	302	0.344
respiratory gaseous exchange	GO:0007585	43	0.342	Mouse
regulation of branching involved in ureteric bud morphogenesis	GO:0090189	22	0.338	Mouse
renal system development	GO:0072001	225	0.337	Mouse
lung morphogenesis	GO:0060425	50	0.333	Mouse
cardiac epithelial to mesenchymal transition	GO:0060317	18	0.331
mammary gland epithelium development	GO:0061180	65	0.324	Mouse
digestive tract morphogenesis	GO:0048546	147	0.323
mammary gland epithelial cell proliferation	GO:0033598	24	0.319	Mouse
multicellular organism growth	GO:0035264	161	0.318	Mouse
striated muscle tissue development	GO:0014706	293	0.316
lung cell differentiation	GO:0060479	30	0.315	Mouse
skeletal muscle organ development	GO:0060538	163	0.314
mesenchyme morphogenesis	GO:0072132	32	0.308
olfactory bulb development	GO:0021772	30	0.304
stem cell development	GO:0048864	219	0.302
regulation of cellular amino acid metabolic process	GO:0006521	5	0.302
kidney morphogenesis	GO:0060993	83	0.302	Mouse
regulation of bmp signaling pathway	GO:0030510	60	0.301
mesonephric epithelium development	GO:0072163	94	0.299	Mouse
paraxial mesodermal cell differentiation	GO:0048342	2	0.299
cell fate commitment	GO:0045165	210	0.295
cell type specific apoptotic process	GO:0097285	268	0.294
somitogenesis	GO:0001756	69	0.294
respiratory system development	GO:0060541	190	0.291	Mouse
angiogenesis	GO:0001525	201	0.291
outflow tract morphogenesis	GO:0003151	53	0.286
morphogenesis of a branching structure	GO:0001763	203	0.285	Mouse
positive regulation of apoptotic process	GO:0043065	217	0.283
development of primary female sexual characteristics	GO:0046545	73	0.282
bone development	GO:0060348	120	0.281	Mouse
segmentation	GO:0035282	93	0.281
gastrulation	GO:0007369	116	0.280
intestinal epithelial cell development	GO:0060576	12	0.279	Mouse
cytokine production	GO:0001816	319	0.279
regulation of neuron differentiation	GO:0045664	281	0.278
peripheral nervous system neuron development	GO:0048935	9	0.276
respiratory tube development	GO:0030323	167	0.274	Mouse
limb morphogenesis	GO:0035108	149	0.272
sensory organ morphogenesis	GO:0090596	242	0.272
adult locomotory behavior	GO:0008344	91	0.266	Mouse
embryonic digit morphogenesis	GO:0042733	56	0.266
regulation of cytokine production	GO:0001817	266	0.262
ear morphogenesis	GO:0042471	118	0.262
appendage morphogenesis	GO:0035107	149	0.261
neural crest cell development	GO:0014032	48	0.252
stem cell proliferation	GO:0072089	117	0.251
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	GO:2000802	1	0.250
brain morphogenesis	GO:0048854	32	0.249
forebrain neuron development	GO:0021884	30	0.246
mesonephric duct morphogenesis	GO:0072180	4	0.243
spinal cord association neuron differentiation	GO:0021527	14	0.242
homeostasis of number of cells	GO:0048872	210	0.241	Mouse
cellular response to growth factor stimulus	GO:0071363	197	0.240
heart morphogenesis	GO:0003007	178	0.239
diencephalon development	GO:0021536	63	0.237
myeloid cell homeostasis	GO:0002262	114	0.235	Mouse
axon guidance	GO:0007411	141	0.235
positive regulation of neuron differentiation	GO:0045666	141	0.234
mesenchymal cell development	GO:0014031	93	0.232
sensory perception	GO:0007600	245	0.229	Mouse
mesenchymal epithelial cell signaling	GO:0060638	9	0.227	Mouse
morphogenesis of a branching epithelium	GO:0061138	193	0.227	Mouse
nephron epithelium development	GO:0072009	92	0.222	Mouse
epithelial cell development	GO:0002064	159	0.218	Mouse
positive regulation of kidney development	GO:0090184	28	0.218	Mouse
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process	GO:2000763	1	0.211
regulation of myeloid cell differentiation	GO:0045637	96	0.210	Mouse
cell proliferation involved in outflow tract morphogenesis	GO:0061325	4	0.208
pyramidal neuron migration	GO:0021852	1	0.208
lung associated mesenchyme development	GO:0060484	10	0.208	Mouse
hypophysis morphogenesis	GO:0048850	3	0.207
telencephalon development	GO:0021537	186	0.206
positive regulation of mesonephros development	GO:0061213	20	0.200	Mouse
gonad development	GO:0008406	141	0.200
ion transmembrane transport	GO:0034220	361	0.197
positive regulation of peptidase activity	GO:0010952	49	0.196
positive regulation of cellular amine metabolic process	GO:0033240	5	0.195
cell proliferation in hindbrain	GO:0021534	10	0.195
inner ear morphogenesis	GO:0042472	101	0.191
mitotic cell cycle process	GO:1903047	159	0.191
amine metabolic process	GO:0009308	45	0.189
leukocyte differentiation	GO:0002521	342	0.188
mesangial cell differentiation	GO:0072007	4	0.181
epithelial cell morphogenesis	GO:0003382	41	0.180
regulation of angiogenesis	GO:0045765	81	0.178
lung secretory cell differentiation	GO:0061140	13	0.177	Mouse
regulation of secretion	GO:0051046	274	0.176
chemotaxis	GO:0006935	247	0.176
negative regulation of nervous system development	GO:0051961	156	0.175
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	GO:2000800	1	0.173
negative regulation of growth	GO:0045926	99	0.172
neural tube closure	GO:0001843	90	0.172
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.171
skin development	GO:0043588	220	0.171
bronchus development	GO:0060433	10	0.170	Mouse
connective tissue development	GO:0061448	179	0.169	Mouse
embryonic forelimb morphogenesis	GO:0035115	32	0.168
neural precursor cell proliferation	GO:0061351	121	0.165
pituitary gland development	GO:0021983	38	0.165
artery development	GO:0060840	53	0.163
neural crest cell differentiation	GO:0014033	54	0.163
peripheral nervous system development	GO:0007422	53	0.162
intestinal epithelial cell differentiation	GO:0060575	14	0.161	Mouse
positive regulation of keratinocyte proliferation	GO:0010838	4	0.159
developmental maturation	GO:0021700	193	0.157	Mouse
apoptotic process involved in morphogenesis	GO:0060561	25	0.157
positive regulation of stem cell proliferation	GO:2000648	59	0.156
chondrocyte differentiation	GO:0002062	72	0.155
neural tube formation	GO:0001841	108	0.153
regulation of vasculature development	GO:1901342	88	0.153
carbon catabolite repression of transcription from rna polymerase ii promoter	GO:0000437	1	0.152
negative regulation of wnt signaling pathway	GO:0030178	73	0.152
pancreatic a cell fate commitment	GO:0003326	2	0.151
columnar cuboidal epithelial cell development	GO:0002066	29	0.151	Mouse
cellular calcium ion homeostasis	GO:0006874	119	0.151
hindbrain development	GO:0030902	128	0.150
cardiac neural crest cell migration involved in outflow tract morphogenesis	GO:0003253	3	0.149
endochondral bone morphogenesis	GO:0060350	50	0.149
embryonic epithelial tube formation	GO:0001838	130	0.147
mesoderm development	GO:0007498	100	0.147
forebrain generation of neurons	GO:0021872	63	0.144
positive regulation of epithelial cell proliferation	GO:0050679	68	0.143
auditory receptor cell differentiation	GO:0042491	37	0.142
female sex differentiation	GO:0046660	84	0.142
mesonephros development	GO:0001823	97	0.142	Mouse
cellular homeostasis	GO:0019725	240	0.141
forelimb morphogenesis	GO:0035136	40	0.139
cofactor transport	GO:0051181	4	0.139
negative regulation of endothelial cell migration	GO:0010596	4	0.138
fat cell differentiation	GO:0045444	160	0.138
regulation of kidney development	GO:0090183	40	0.137	Mouse
placenta development	GO:0001890	140	0.136
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.135	Mouse
sclerotome development	GO:0061056	4	0.135
axis elongation involved in somitogenesis	GO:0090245	4	0.135
endocardial cushion to mesenchymal transition involved in heart valve formation	GO:0003199	4	0.135
ameboidal type cell migration	GO:0001667	128	0.132
ear development	GO:0043583	200	0.132
regulation of secretion by cell	GO:1903530	249	0.132
regulation of retina development in camera type eye	GO:1902866	3	0.130
limbic system development	GO:0021761	72	0.130
neural crest cell migration	GO:0001755	32	0.130
astrocyte fate commitment	GO:0060018	4	0.129
blood circulation	GO:0008015	195	0.129
forebrain neuron differentiation	GO:0021879	52	0.129
somatic stem cell division	GO:0048103	19	0.127	Mouse
regulation of cartilage development	GO:0061035	44	0.126
lymphocyte differentiation	GO:0030098	242	0.125
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.124
autonomic nervous system development	GO:0048483	43	0.124
adult behavior	GO:0030534	135	0.124	Mouse
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	GO:0060528	4	0.123
divalent metal ion transport	GO:0070838	172	0.123
glomerular mesangial cell differentiation	GO:0072008	3	0.123
tube formation	GO:0035148	140	0.123
regulation of neural precursor cell proliferation	GO:2000177	70	0.123
morphogenesis of embryonic epithelium	GO:0016331	159	0.122
regulation of neural retina development	GO:0061074	3	0.118
skeletal muscle cell differentiation	GO:0035914	66	0.118
regulation of hydrolase activity	GO:0051336	246	0.116
aortic valve morphogenesis	GO:0003180	4	0.116
development of primary sexual characteristics	GO:0045137	143	0.114
hindlimb morphogenesis	GO:0035137	42	0.112
regulation of stem cell proliferation	GO:0072091	78	0.111
canonical wnt signaling pathway	GO:0060070	130	0.111
cellular ketone metabolic process	GO:0042180	84	0.111
development of primary male sexual characteristics	GO:0046546	88	0.109
kidney development	GO:0001822	213	0.108	Mouse
camera type eye development	GO:0043010	266	0.108
multicellular organismal signaling	GO:0035637	91	0.108
ovulation cycle	GO:0042698	59	0.108
cell proliferation in forebrain	GO:0021846	30	0.107
pattern specification involved in metanephros development	GO:0072268	4	0.107
negative regulation of molecular function	GO:0044092	258	0.107
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.107
semaphorin plexin signaling pathway involved in outflow tract morphogenesis	GO:0071527	1	0.105
positive regulation of endopeptidase activity	GO:0010950	43	0.105
regulation of cell size	GO:0008361	72	0.104
regulation of membrane potential	GO:0042391	192	0.104
organic hydroxy compound transport	GO:0015850	93	0.103
positive regulation of fat cell differentiation	GO:0045600	32	0.102
cation homeostasis	GO:0055080	212	0.100
cardiac muscle tissue morphogenesis	GO:0055008	44	0.099
neuroblast proliferation	GO:0007405	49	0.098
odontogenesis	GO:0042476	78	0.097
metal ion homeostasis	GO:0055065	189	0.097
regulation of fat cell differentiation	GO:0045598	81	0.096
endocrine pancreas development	GO:0031018	29	0.096
membrane organization	GO:0061024	245	0.096
cellular lipid metabolic process	GO:0044255	323	0.095
cellular amine metabolic process	GO:0044106	44	0.094
negative regulation of protein processing	GO:0010955	79	0.094
positive regulation of secretion by cell	GO:1903532	114	0.094
auditory receptor cell fate specification	GO:0042667	1	0.094
positive regulation of inner ear receptor cell differentiation	GO:2000982	1	0.093
female gonad development	GO:0008585	71	0.092
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.091
wnt signaling pathway	GO:0016055	188	0.091
male gamete generation	GO:0048232	285	0.091
hippocampus development	GO:0021766	52	0.090
regulation of cellular ketone metabolic process	GO:0010565	66	0.089
positive regulation of auditory receptor cell differentiation	GO:0045609	1	0.089
cell adhesion	GO:0007155	329	0.089
spermatogenesis	GO:0007283	284	0.088
planar cell polarity pathway involved in outflow tract morphogenesis	GO:0061347	2	0.087
regulation of neuron projection development	GO:0010975	169	0.087
endocardial cushion to mesenchymal transition	GO:0090500	5	0.086
cardiac chamber development	GO:0003205	108	0.086
cardiac ventricle development	GO:0003231	83	0.086
thymus development	GO:0048538	41	0.086
pericardium development	GO:0060039	16	0.085
mammary gland alveolus development	GO:0060749	22	0.085	Mouse
negative regulation of apoptotic process involved in outflow tract morphogenesis	GO:1902257	2	0.085
glomerular mesangial cell development	GO:0072144	3	0.085
divalent inorganic cation homeostasis	GO:0072507	138	0.085
organic hydroxy compound metabolic process	GO:1901615	203	0.085
cell maturation	GO:0048469	127	0.085	Mouse
cardiac right ventricle formation	GO:0003219	3	0.084
male gonad development	GO:0008584	88	0.084
feeding behavior	GO:0007631	62	0.084
cardiac atrium development	GO:0003230	24	0.084
regulation of canonical wnt signaling pathway	GO:0060828	82	0.084
apoptotic process involved in development	GO:1902742	28	0.084
regulation of cell projection organization	GO:0031344	206	0.083
extracellular matrix organization	GO:0030198	147	0.083
neural tube development	GO:0021915	160	0.083
epithelial tube formation	GO:0072175	130	0.083
neuron fate determination	GO:0048664	9	0.083
phenol containing compound metabolic process	GO:0018958	60	0.083
regulation of oxidative phosphorylation uncoupler activity	GO:2000275	3	0.083
primitive streak formation	GO:0090009	10	0.082
cardiac right atrium morphogenesis	GO:0003213	3	0.082
visceral serous pericardium development	GO:0061032	2	0.082
oviduct development	GO:0060066	3	0.081
carbon catabolite activation of transcription from rna polymerase ii promoter	GO:0000436	4	0.081
peptide hormone secretion	GO:0030072	109	0.080
positive regulation of cell development	GO:0010720	237	0.080
cation transport	GO:0006812	399	0.080
bone morphogenesis	GO:0060349	78	0.080
midbrain hindbrain boundary maturation	GO:0021732	1	0.079
regulation of leukocyte differentiation	GO:1902105	159	0.079
paramesonephric duct development	GO:0061205	3	0.079
regulation of interleukin 1 alpha production	GO:0032650	4	0.079
negative regulation of cell proliferation	GO:0008285	296	0.079
planar cell polarity pathway involved in pericardium morphogenesis	GO:0061354	2	0.079
mitochondrion organization	GO:0007005	134	0.079
collagen fibril organization	GO:0030199	32	0.078
intracellular protein transport	GO:0006886	204	0.078
hormone secretion	GO:0046879	128	0.078
ventral spinal cord interneuron fate commitment	GO:0060579	14	0.078
heart formation	GO:0060914	16	0.077
establishment of organ orientation	GO:0048561	1	0.077
subpallium neuron fate commitment	GO:0060163	2	0.076
positive regulation of secondary heart field cardioblast proliferation	GO:0072513	4	0.075
cardiac chamber morphogenesis	GO:0003206	93	0.075
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis	GO:2000764	1	0.075
cellular ion homeostasis	GO:0006873	165	0.075
cellular response to extracellular stimulus	GO:0031668	81	0.075
compound eye development	GO:0048749	1	0.074
positive regulation of cytokine production	GO:0001819	174	0.073
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification	GO:0021913	4	0.073
positive regulation of angiogenesis	GO:0045766	46	0.072
sprouting angiogenesis	GO:0002040	26	0.072
muscle contraction	GO:0006936	101	0.072
regulation of homeostatic process	GO:0032844	182	0.072
forebrain cell migration	GO:0021885	58	0.072
positive regulation of transcription by glucose	GO:0046016	3	0.071
steroid metabolic process	GO:0008202	119	0.071
regulation of wnt signaling pathway	GO:0030111	123	0.071
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000079	1	0.071
tissue remodeling	GO:0048771	102	0.071
stem cell division	GO:0017145	30	0.071	Mouse
pallium development	GO:0021543	120	0.071
negative regulation of blood vessel endothelial cell migration	GO:0043537	3	0.070
muscle cell differentiation	GO:0042692	261	0.070
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.070
embryonic heart tube development	GO:0035050	65	0.070
olfactory lobe development	GO:0021988	32	0.070
positive regulation of transcription from rna polymerase ii promoter by glucose	GO:0000432	3	0.070
small molecule biosynthetic process	GO:0044283	132	0.070
response to growth factor	GO:0070848	198	0.070
chromatin modification	GO:0016568	187	0.069
rhythmic process	GO:0048511	174	0.069
cellular response to lipid	GO:0071396	145	0.069
cervix development	GO:0060067	2	0.069
protein ubiquitination	GO:0016567	171	0.068
regulation of organ formation	GO:0003156	34	0.068
t cell activation	GO:0042110	289	0.068
negative regulation of cellular protein metabolic process	GO:0032269	247	0.067
ossification	GO:0001503	216	0.067
ventricular septum development	GO:0003281	42	0.067
positive regulation of branching involved in ureteric bud morphogenesis	GO:0090190	18	0.067	Mouse
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.066
metanephric nephron morphogenesis	GO:0072273	19	0.066
negative regulation of synapse maturation	GO:2000297	2	0.066
organonitrogen compound biosynthetic process	GO:1901566	192	0.066
nephron tubule formation	GO:0072079	20	0.066
forebrain morphogenesis	GO:0048853	17	0.066
synaptic transmission	GO:0007268	329	0.066
cardiac septum development	GO:0003279	59	0.066
lung goblet cell differentiation	GO:0060480	5	0.065	Mouse
interleukin 1 production	GO:0032612	31	0.065
regulation of ion transport	GO:0043269	215	0.064
neuromuscular process	GO:0050905	99	0.063
regulation of hormone levels	GO:0010817	211	0.063
hair cycle	GO:0042633	90	0.063
regulation of lipid biosynthetic process	GO:0046890	54	0.063
multi multicellular organism process	GO:0044706	109	0.063
endocardial cushion morphogenesis	GO:0003203	18	0.063
cell proliferation involved in heart valve development	GO:2000793	2	0.062
negative regulation of bmp signaling pathway	GO:0030514	35	0.062
mesoderm formation	GO:0001707	62	0.062
cerebral cortex development	GO:0021987	86	0.062
endocytosis	GO:0006897	168	0.062
ventricular trabecula myocardium morphogenesis	GO:0003222	11	0.062
peripheral nervous system neuron differentiation	GO:0048934	9	0.062
kidney rudiment formation	GO:0072003	3	0.061
response to organonitrogen compound	GO:0010243	246	0.061
epithelial mesenchymal signaling involved in prostate gland development	GO:0060738	2	0.061
molting cycle	GO:0042303	90	0.061
cellular response to organonitrogen compound	GO:0071417	145	0.061
epithelial cell maturation	GO:0002070	15	0.061	Mouse
head morphogenesis	GO:0060323	34	0.060
carbohydrate transport	GO:0008643	62	0.060
organonitrogen compound catabolic process	GO:1901565	264	0.060
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.059
cardiac muscle tissue development	GO:0048738	130	0.059
action potential	GO:0001508	78	0.059
regulation of lymphocyte activation	GO:0051249	240	0.059
regulation of system process	GO:0044057	200	0.059
cardiac septum morphogenesis	GO:0060411	46	0.059
neural tube patterning	GO:0021532	43	0.058
positive regulation of transcription from rna polymerase iii promoter	GO:0045945	1	0.058
cell differentiation in hindbrain	GO:0021533	24	0.058
prostate gland stromal morphogenesis	GO:0060741	2	0.058
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation	GO:0003257	3	0.058
cellular metal ion homeostasis	GO:0006875	151	0.058
central nervous system vasculogenesis	GO:0022009	3	0.058
regulation of proteolysis	GO:0030162	164	0.058
cerebellar granule cell precursor proliferation	GO:0021930	10	0.057
multicellular organismal response to stress	GO:0033555	62	0.057
lipid biosynthetic process	GO:0008610	179	0.057
mesenchymal to epithelial transition	GO:0060231	12	0.057
positive regulation of epithelial cell proliferation involved in lung morphogenesis	GO:0060501	3	0.057
middle ear morphogenesis	GO:0042474	23	0.057
regulation of androgen receptor signaling pathway	GO:0060765	3	0.057
glial cell differentiation	GO:0010001	131	0.056
regulation of morphogenesis of a branching structure	GO:0060688	53	0.056	Mouse
regulation of neuroblast proliferation	GO:1902692	27	0.056
regulation of kinase activity	GO:0043549	249	0.055
endodermal cell fate specification	GO:0001714	4	0.055
negative regulation of transcription from rna polymerase ii promoter by glucose	GO:0000433	1	0.055
response to extracellular stimulus	GO:0009991	127	0.055
auditory receptor cell fate determination	GO:0042668	3	0.055
heart valve morphogenesis	GO:0003179	21	0.055
pancreatic pp cell fate commitment	GO:0003329	2	0.055
stem cell maintenance	GO:0019827	130	0.054
glucose transport	GO:0015758	56	0.054
hair cell differentiation	GO:0035315	40	0.054
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.054
trachea morphogenesis	GO:0060439	8	0.054	Mouse
cell surface receptor signaling pathway involved in heart development	GO:0061311	15	0.054
muscle tissue morphogenesis	GO:0060415	53	0.054
lateral sprouting involved in mammary gland duct morphogenesis	GO:0060599	2	0.054
embryonic heart tube morphogenesis	GO:0003143	51	0.054
cell chemotaxis	GO:0060326	81	0.053
anion transport	GO:0006820	177	0.053
mesangial cell development	GO:0072143	4	0.053
regulation of mesenchymal cell proliferation	GO:0010464	37	0.053
rhombomere 3 morphogenesis	GO:0021658	2	0.053
regulation of cell cycle	GO:0051726	281	0.052
cellular macromolecule catabolic process	GO:0044265	206	0.052
cellular response to inorganic substance	GO:0071241	37	0.052
mitral valve morphogenesis	GO:0003183	4	0.052
embryonic heart tube formation	GO:0003144	1	0.052
hemangioblast cell differentiation	GO:0060217	1	0.052
positive regulation of mechanoreceptor differentiation	GO:0045633	1	0.052
t cell differentiation	GO:0030217	174	0.052
response to organic cyclic compound	GO:0014070	198	0.052
renal capsule morphogenesis	GO:0072128	1	0.051
purine containing compound metabolic process	GO:0072521	311	0.050
positive regulation of apoptotic process involved in morphogenesis	GO:1902339	4	0.050
somatotropin secreting cell differentiation	GO:0060126	4	0.050
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.050
forebrain neuron fate commitment	GO:0021877	13	0.050
positive regulation of transcription from rna polymerase ii promoter involved in heart development	GO:1901228	4	0.050
inner medullary collecting duct development	GO:0072061	2	0.050
uterus development	GO:0060065	16	0.049
tendon formation	GO:0035992	4	0.049
positive regulation of proteolysis	GO:0045862	85	0.049
regulation of lymphocyte proliferation	GO:0050670	117	0.049
positive regulation of cell projection organization	GO:0031346	95	0.049
ovarian follicle development	GO:0001541	40	0.049
gliogenesis	GO:0042063	141	0.049
protein secretion	GO:0009306	111	0.049
protein localization to organelle	GO:0033365	185	0.049
negative regulation of neuron differentiation	GO:0045665	101	0.049
monocarboxylic acid metabolic process	GO:0032787	191	0.048
cellular response to external stimulus	GO:0071496	88	0.048
glossopharyngeal nerve morphogenesis	GO:0021615	4	0.048
renal capsule specification	GO:0072130	1	0.048
positive regulation of protein phosphorylation	GO:0001934	242	0.048

Hoxc6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.056
	nervous system disease	DOID:863	0	0.056

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