| pigment accumulation | GO:0043476 | 1 | 1.000 | |
| establishment of melanosome localization | GO:0032401 | 11 | 0.993 | |
| pigment granule localization | GO:0051875 | 13 | 0.967 | |
| melanosome transport | GO:0032402 | 11 | 0.925 | |
| melanosome localization | GO:0032400 | 12 | 0.922 | |
| coagulation | GO:0050817 | 78 | 0.902 | |
| melanosome organization | GO:0032438 | 8 | 0.853 | |
| anterograde synaptic vesicle transport | GO:0048490 | 15 | 0.844 | |
| anterograde axon cargo transport | GO:0008089 | 20 | 0.826 | |
| microtubule based transport | GO:0010970 | 50 | 0.825 | |
| blood coagulation | GO:0007596 | 76 | 0.790 | |
| microtubule based movement | GO:0007018 | 84 | 0.773 | |
| hemostasis | GO:0007599 | 78 | 0.766 | |
| pigment granule transport | GO:0051904 | 12 | 0.731 | |
| regulation of natural killer cell activation | GO:0032814 | 22 | 0.712 | |
| vesicle localization | GO:0051648 | 86 | 0.687 | |
| cytoskeleton dependent intracellular transport | GO:0030705 | 50 | 0.679 | |
| pigment cell differentiation | GO:0050931 | 27 | 0.629 | |
| pigmentation | GO:0043473 | 71 | 0.627 | |
| cellular pigmentation | GO:0033059 | 20 | 0.583 | |
| secretion of lysosomal enzymes | GO:0033299 | 6 | 0.555 | |
| melanocyte differentiation | GO:0030318 | 25 | 0.550 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.525 | |
| developmental pigmentation | GO:0048066 | 40 | 0.492 | Zebrafish |
| synaptic vesicle localization | GO:0097479 | 59 | 0.436 | |
| secretory granule organization | GO:0033363 | 20 | 0.400 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.383 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.353 | |
| axon cargo transport | GO:0008088 | 33 | 0.345 | |
| natural killer cell degranulation | GO:0043320 | 3 | 0.329 | |
| pigment granule organization | GO:0048753 | 9 | 0.316 | |
| natural killer cell activation | GO:0030101 | 44 | 0.312 | |
| organelle localization | GO:0051640 | 179 | 0.304 | |
| synaptic transmission | GO:0007268 | 329 | 0.303 | |
| lytic vacuole organization | GO:0080171 | 21 | 0.284 | |
| positive regulation of natural killer cell activation | GO:0032816 | 15 | 0.283 | |
| vesicle organization | GO:0016050 | 60 | 0.273 | |
| positive regulation of lymphocyte activation | GO:0051251 | 140 | 0.272 | |
| wound healing | GO:0042060 | 157 | 0.268 | |
| natural killer cell activation involved in immune response | GO:0002323 | 10 | 0.245 | |
| establishment of synaptic vesicle localization | GO:0097480 | 57 | 0.220 | |
| regulation of pigment cell differentiation | GO:0050932 | 7 | 0.181 | |
| establishment of pigment granule localization | GO:0051905 | 12 | 0.175 | |
| microtubule based process | GO:0007017 | 236 | 0.174 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.165 | |
| synaptic vesicle transport | GO:0048489 | 57 | 0.153 | |
| endomembrane system organization | GO:0010256 | 147 | 0.148 | |
| neuroepithelial cell differentiation | GO:0060563 | 37 | 0.146 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.144 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.142 | |
| regulation of cell activation | GO:0050865 | 289 | 0.121 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.120 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.092 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.090 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 2 | 0.088 | |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 82 | 0.084 | |
| lysosome organization | GO:0007040 | 21 | 0.083 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.082 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.081 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.076 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.073 | |
| antigen processing and presentation of lipid antigen via mhc class ib | GO:0048003 | 3 | 0.072 | |
| positive regulation of reactive oxygen species biosynthetic process | GO:1903428 | 2 | 0.071 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.070 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.068 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.067 | |
| transmembrane transport | GO:0055085 | 412 | 0.067 | |
| exosomal secretion | GO:1990182 | 1 | 0.066 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.065 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.062 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.061 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.061 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.059 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.059 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.057 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.057 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.055 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.054 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.054 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.054 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.054 | |
| eye pigmentation | GO:0048069 | 3 | 0.053 | Zebrafish |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.053 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.052 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.051 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.051 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.051 | |
| camera type eye development | GO:0043010 | 266 | 0.049 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.049 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.048 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.045 | |
| cytotoxic t cell degranulation | GO:0043316 | 2 | 0.044 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.044 | |
| protein targeting | GO:0006605 | 143 | 0.044 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.043 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.043 | |
| gtp metabolic process | GO:0046039 | 144 | 0.043 | |
| neuromuscular process | GO:0050905 | 99 | 0.043 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.043 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.042 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.042 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.041 | |
| protein targeting to vacuole | GO:0006623 | 3 | 0.041 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.040 | |
| vacuole organization | GO:0007033 | 38 | 0.039 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.039 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.038 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.038 | |
| immune effector process | GO:0002252 | 321 | 0.038 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.038 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.038 | |
| t cell differentiation | GO:0030217 | 174 | 0.038 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.038 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.038 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.037 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.036 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.035 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.035 | |
| membrane organization | GO:0061024 | 245 | 0.035 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.034 | |
| lipid homeostasis | GO:0055088 | 63 | 0.034 | |
| establishment of protein localization to vacuole | GO:0072666 | 4 | 0.033 | |
| lipid localization | GO:0010876 | 126 | 0.033 | |
| regulation of endocytosis | GO:0030100 | 69 | 0.032 | |
| protein localization to vacuole | GO:0072665 | 4 | 0.032 | |
| intracellular protein transport | GO:0006886 | 204 | 0.031 | |
| defense response to bacterium | GO:0042742 | 119 | 0.031 | |
| natural killer cell mediated cytotoxicity | GO:0042267 | 29 | 0.030 | |
| protein secretion | GO:0009306 | 111 | 0.030 | |
| t cell activation | GO:0042110 | 289 | 0.029 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.028 | |
| positive regulation of pigment cell differentiation | GO:0050942 | 5 | 0.028 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.028 | |
| protein catabolic process | GO:0030163 | 221 | 0.028 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.028 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.028 | |
| positive regulation of phagocytosis | GO:0050766 | 26 | 0.027 | |
| neuromuscular process controlling balance | GO:0050885 | 59 | 0.027 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.027 | |
| positive regulation of reactive oxygen species metabolic process | GO:2000379 | 11 | 0.026 | |
| cellular homeostasis | GO:0019725 | 240 | 0.026 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.026 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.026 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.025 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 34 | 0.025 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.025 | |
| cell adhesion | GO:0007155 | 329 | 0.025 | |
| adaptive immune response | GO:0002250 | 155 | 0.025 | |
| cation transport | GO:0006812 | 399 | 0.024 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 86 | 0.024 | |
| amine metabolic process | GO:0009308 | 45 | 0.024 | |
| early endosome to late endosome transport | GO:0045022 | 2 | 0.024 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.024 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.024 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.023 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.023 | |
| regulation of ion transport | GO:0043269 | 215 | 0.023 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.023 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.022 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.022 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.022 | |
| phospholipid metabolic process | GO:0006644 | 87 | 0.022 | |
| gtp catabolic process | GO:0006184 | 143 | 0.021 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.021 | |
| protein targeting to lysosome | GO:0006622 | 2 | 0.021 | |
| ear morphogenesis | GO:0042471 | 118 | 0.021 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.021 | |
| endosome organization | GO:0007032 | 9 | 0.021 | |
| ear development | GO:0043583 | 200 | 0.021 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.021 | |
| leukocyte mediated cytotoxicity | GO:0001909 | 62 | 0.020 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.020 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.020 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.020 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.019 | |
| antigen processing and presentation | GO:0019882 | 47 | 0.019 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.019 | |
| natural killer cell mediated immunity | GO:0002228 | 29 | 0.019 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.019 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.019 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.019 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.018 | |
| cation homeostasis | GO:0055080 | 212 | 0.018 | |
| neurotransmitter transport | GO:0006836 | 76 | 0.018 | |
| retina development in camera type eye | GO:0060041 | 119 | 0.018 | |
| phagocytosis | GO:0006909 | 66 | 0.018 | |
| cell activation involved in immune response | GO:0002263 | 126 | 0.018 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.018 | |
| endocytosis | GO:0006897 | 168 | 0.018 | |
| membrane fusion | GO:0061025 | 38 | 0.018 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.017 | |
| protein maturation | GO:0051604 | 176 | 0.017 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.017 | |
| regulation of alpha beta t cell activation | GO:0046634 | 53 | 0.017 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.017 | |
| platelet activation | GO:0030168 | 40 | 0.017 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.017 | |
| maintenance of location | GO:0051235 | 89 | 0.016 | |
| glucose homeostasis | GO:0042593 | 128 | 0.016 | |
| interleukin 8 production | GO:0032637 | 4 | 0.016 | |
| lipid biosynthetic process | GO:0008610 | 179 | 0.016 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.016 | |
| innate immune response | GO:0045087 | 157 | 0.016 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.016 | |
| protein localization to organelle | GO:0033365 | 185 | 0.016 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.016 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.015 | |
| cell killing | GO:0001906 | 67 | 0.015 | |
| chromatin modification | GO:0016568 | 187 | 0.015 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.015 | |
| urogenital system development | GO:0001655 | 261 | 0.015 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.015 | |
| compound eye development | GO:0048749 | 1 | 0.015 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.014 | |
| regulation of phagocytosis | GO:0050764 | 33 | 0.014 | |
| alpha beta t cell differentiation | GO:0046632 | 69 | 0.014 | |
| lymphocyte activation involved in immune response | GO:0002285 | 93 | 0.014 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.014 | |
| oxidation reduction process | GO:0055114 | 342 | 0.014 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.014 | |
| platelet aggregation | GO:0070527 | 20 | 0.014 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.014 | |
| protein processing | GO:0016485 | 163 | 0.014 | |
| regulation of t cell differentiation | GO:0045580 | 83 | 0.014 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.014 | |
| muscle tissue development | GO:0060537 | 308 | 0.014 | |
| regulation of interleukin 8 production | GO:0032677 | 3 | 0.013 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.013 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.013 | |
| pigment metabolic process | GO:0042440 | 32 | 0.013 | |
| positive regulation of endocytosis | GO:0045807 | 42 | 0.013 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.013 | |
| glycoprotein metabolic process | GO:0009100 | 116 | 0.013 | |
| cytokine production | GO:0001816 | 319 | 0.012 | |
| adult behavior | GO:0030534 | 135 | 0.012 | |
| anion transport | GO:0006820 | 177 | 0.012 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.012 | |
| organelle assembly | GO:0070925 | 177 | 0.012 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.012 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.012 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.012 | |
| alpha amino acid metabolic process | GO:1901605 | 59 | 0.012 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.012 | |
| male gamete generation | GO:0048232 | 285 | 0.012 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.012 | |
| neuronal action potential | GO:0019228 | 54 | 0.012 | |
| glycoprotein biosynthetic process | GO:0009101 | 89 | 0.012 | |
| neurotransmitter secretion | GO:0007269 | 62 | 0.012 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.012 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.012 | |
| single organismal cell cell adhesion | GO:0016337 | 131 | 0.012 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.011 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.011 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.011 | |
| positive regulation of lymphocyte differentiation | GO:0045621 | 61 | 0.011 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.011 | |
| protein ubiquitination | GO:0016567 | 171 | 0.011 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.011 | |
| rna interference | GO:0016246 | 2 | 0.011 | |
| t cell mediated immunity | GO:0002456 | 50 | 0.011 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.011 | |
| dephosphorylation | GO:0016311 | 129 | 0.011 | |
| organic anion transport | GO:0015711 | 137 | 0.011 | |
| renal system development | GO:0072001 | 225 | 0.011 | |
| leukocyte activation involved in immune response | GO:0002366 | 126 | 0.011 | |
| asymmetric stem cell division | GO:0098722 | 3 | 0.011 | |
| positive regulation of t cell differentiation | GO:0045582 | 52 | 0.011 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.011 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.011 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.011 | |
| homotypic cell cell adhesion | GO:0034109 | 28 | 0.011 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.011 | |
| carboxylic acid biosynthetic process | GO:0046394 | 86 | 0.011 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.011 | |
| tissue remodeling | GO:0048771 | 102 | 0.011 | |
| calcium ion dependent exocytosis | GO:0017156 | 35 | 0.011 | |
| hormone secretion | GO:0046879 | 128 | 0.011 | |
| organic acid biosynthetic process | GO:0016053 | 86 | 0.011 | |
| small molecule biosynthetic process | GO:0044283 | 132 | 0.010 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.010 | |
| gonad development | GO:0008406 | 141 | 0.010 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.010 | |
| sulfur compound biosynthetic process | GO:0044272 | 37 | 0.010 | |
| positive regulation of interferon alpha production | GO:0032727 | 4 | 0.010 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.010 | |
| ossification | GO:0001503 | 216 | 0.010 | |
| myeloid leukocyte mediated immunity | GO:0002444 | 42 | 0.010 | |
| glycerolipid metabolic process | GO:0046486 | 122 | 0.010 | |
| regulation of exocytosis | GO:0017157 | 61 | 0.010 | |
| positive regulation of developmental pigmentation | GO:0048087 | 6 | 0.010 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.010 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.010 | |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.010 | |