Mus musculus

0 known processes

Igh

immunoglobulin heavy chain complex

(Aliases: MGC6529,MGC102662,MGC102661,MGC6628,MGC28019,MGC6740,MGC6522,MGC118125,MGC103226,MGC6486,MGC68378,MGC36307,MGC68276)

Igh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histamine production involved in inflammatory responseGO:000234911.000
immunoglobulin mediated immune responseGO:0016064691.000
adaptive immune responseGO:00022501551.000
b cell activationGO:00421131611.000
negative regulation of b cell proliferationGO:0030889131.000
interleukin 5 secretionGO:007260321.000
b cell proliferationGO:0042100531.000
regulation of cytokine biosynthetic processGO:0042035591.000
lymphocyte differentiationGO:00300982421.000
positive regulation of cytokine biosynthetic processGO:0042108401.000
interleukin 10 secretionGO:007260841.000
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822871.000
regulation of b cell differentiationGO:0045577231.000
humoral immune response mediated by circulating immunoglobulinGO:0002455141.000
positive regulation of adaptive immune responseGO:0002821610.999
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.999
positive regulation of b cell proliferationGO:0030890240.999
negative regulation of interleukin 5 secretionGO:200066310.999
lymphocyte homeostasisGO:0002260640.999
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.999
immunoglobulin secretionGO:0048305170.999
regulation of interleukin 13 secretionGO:200066520.999
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.999
b cell mediated immunityGO:0019724710.999
somatic diversification of immune receptorsGO:0002200530.998
myeloid dendritic cell differentiationGO:0043011160.998
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.998
regulation of b cell activationGO:0050864810.998
b cell receptor signaling pathwayGO:0050853200.998
lymphocyte mediated immunityGO:00024491390.997
cellular response to dna damage stimulusGO:00069742070.997
positive regulation of b cell activationGO:0050871490.997
positive regulation of immune effector processGO:00026991070.997
dna metabolic processGO:00062593030.997
regulation of inflammatory response to antigenic stimulusGO:0002861210.996
regulation of leukocyte apoptotic processGO:2000106560.996
regulation of calcium ion transport into cytosolGO:0010522310.996
regulation of leukocyte mediated immunityGO:00027031040.995
positive regulation of programmed cell deathGO:00430682180.995
tumor necrosis factor mediated signaling pathwayGO:0033209130.995
positive regulation of leukocyte mediated immunityGO:0002705700.995
toll like receptor signaling pathwayGO:0002224380.993
regulation of leukocyte proliferationGO:00706631210.993
regulation of b cell proliferationGO:0030888390.992
leukocyte mediated immunityGO:00024431740.992
sensitizationGO:004696020.992
regulation of lipid transportGO:0032368360.991
defense response to other organismGO:00985421970.991
b cell differentiationGO:0030183780.991
lymphocyte apoptotic processGO:0070227540.991
negative regulation of leukocyte differentiationGO:1902106510.990
regulation of b cell apoptotic processGO:0002902130.990
somatic diversification of immunoglobulinsGO:0016445430.990
immune response activating signal transductionGO:00027571160.989
alpha beta t cell differentiationGO:0046632690.988
negative regulation of b cell activationGO:0050869270.988
negative regulation of toll like receptor signaling pathwayGO:0034122140.988
positive regulation of leukocyte apoptotic processGO:2000108210.988
dna recombinationGO:0006310920.987
response to amino acidGO:0043200370.984
regulation of b cell mediated immunityGO:0002712370.983
regulation of neutrophil differentiationGO:004565820.983
positive regulation of lymphocyte mediated immunityGO:0002708620.983
homeostasis of number of cellsGO:00488722100.982
interleukin 13 secretionGO:007261120.981
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.980
leukocyte proliferationGO:00706611720.980
positive regulation of cell deathGO:00109422240.979
t cell proliferationGO:00420981200.979
regulation of interleukin 10 secretionGO:200117940.978
regulation of gamma delta t cell differentiationGO:004558690.974
regulation of interleukin 5 secretionGO:200066220.974
thymic t cell selectionGO:0045061220.972
positive regulation of lipid transportGO:0032370220.971
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.970
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.970
b cell homeostasisGO:0001782340.969
regulation of cellular amino acid metabolic processGO:000652150.968
positive regulation of t cell activationGO:00508701010.968
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.968
positive regulation of leukocyte proliferationGO:0070665730.965
positive regulation of interleukin 2 productionGO:0032743190.965
programmed necrotic cell deathGO:0097300280.964
t helper 2 cell differentiationGO:0045064120.963
antigen receptor mediated signaling pathwayGO:0050851640.962
cellular senescenceGO:0090398110.961
regulation of cellular ketone metabolic processGO:0010565660.960
lymph node developmentGO:0048535180.958
regulation of apoptotic signaling pathwayGO:20012331970.956
telomere cappingGO:001623340.953
positive regulation of homeostatic processGO:0032846640.949
regulation of toll like receptor 4 signaling pathwayGO:003414340.947
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.946
regulation of sequence specific dna binding transcription factor activityGO:00510901060.943
glial cell apoptotic processGO:003434930.942
innate immune response activating signal transductionGO:0002758500.942
regulation of lymphocyte proliferationGO:00506701170.940
b cell activation involved in immune responseGO:0002312500.938
t helper 2 cell cytokine productionGO:003574540.938
positive regulation of immunoglobulin mediated immune responseGO:0002891260.938
regulation of lymphocyte mediated immunityGO:0002706840.937
neutrophil differentiationGO:003022330.935
mammary gland epithelium developmentGO:0061180650.934
humoral immune responseGO:0006959570.933
release of cytochrome c from mitochondriaGO:0001836230.932
positive regulation of gamma delta t cell differentiationGO:004558860.927
somatic cell dna recombinationGO:0016444510.926
myd88 independent toll like receptor signaling pathwayGO:000275630.926
regulation of response to woundingGO:19030341890.926
regulation of tumor necrosis factor biosynthetic processGO:0042534100.924
interleukin 10 productionGO:0032613230.924
lipid transportGO:0006869980.923
positive regulation of cellular amine metabolic processGO:003324050.920
positive regulation of podosome assemblyGO:007180330.918
regulation of stress activated mapk cascadeGO:0032872690.918
cellular chemical homeostasisGO:00550822150.918
apoptotic signaling pathwayGO:00971903060.917
circadian rhythmGO:00076231140.916
cytokine production involved in immune responseGO:0002367340.916
immune response regulating signaling pathwayGO:00027641250.914
alpha beta t cell lineage commitmentGO:000236370.913
negative regulation of protein serine threonine kinase activityGO:0071901490.911
positive regulation of multi organism processGO:0043902260.910
negative regulation of cellular amine metabolic processGO:003323910.907
histamine secretionGO:000182110.906
leukocyte differentiationGO:00025213420.906
regulation of calcium ion transportGO:0051924690.905
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.904
response to inorganic substanceGO:0010035960.902
regulation of immunoglobulin mediated immune responseGO:0002889370.901
negative regulation of cell activationGO:00508661110.900
anatomical structure homeostasisGO:00602491450.900
positive regulation of cytokine productionGO:00018191740.899
hematopoietic progenitor cell differentiationGO:00022441430.897
cellular amine metabolic processGO:0044106440.897
regulation of homeostatic processGO:00328441820.895
regulation of toll like receptor 2 signaling pathwayGO:003413530.893
positive regulation of cell developmentGO:00107202370.889
immunoglobulin productionGO:0002377730.887
extrinsic apoptotic signaling pathwayGO:00971911260.886
t cell activation involved in immune responseGO:0002286430.884
regulation of intracellular transportGO:00323861590.881
t cell differentiationGO:00302171740.880
macromolecule methylationGO:00434141200.878
positive regulation of mapk cascadeGO:00434101700.878
chromatin organizationGO:00063252060.872
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.871
regulation of chromatin modificationGO:1903308570.870
positive regulation of isotype switching to igg isotypesGO:004830470.869
tissue remodelingGO:00487711020.868
immune response activating cell surface receptor signaling pathwayGO:0002429720.864
regulation of interleukin 2 productionGO:0032663280.861
regulation of endopeptidase activityGO:0052548890.860
metal ion homeostasisGO:00550651890.857
positive regulation of antibacterial peptide biosynthetic processGO:000696310.853
lymphocyte proliferationGO:00466511640.851
glycosphingolipid metabolic processGO:0006687180.851
tyrosine phosphorylation of stat proteinGO:0007260230.844
dendritic cell differentiationGO:0097028260.843
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.839
positive regulation of intracellular transportGO:0032388700.838
regulation of antigen receptor mediated signaling pathwayGO:0050854290.833
cellular response to external stimulusGO:0071496880.829
t cell differentiation in thymusGO:0033077770.828
regulation of zinc ion transmembrane transportGO:007158020.827
regulation of ion transportGO:00432692150.827
regulation of homotypic cell cell adhesionGO:0034110130.816
positive regulation of translational initiationGO:004594840.814
activation of immune responseGO:00022531380.813
positive t cell selectionGO:0043368230.812
positive regulation of apoptotic processGO:00430652170.812
positive regulation of interleukin 12 productionGO:0032735210.812
hypomethylation of cpg islandGO:004402910.808
regulation of cell activationGO:00508652890.808
amine metabolic processGO:0009308450.806
positive regulation of myeloid cell differentiationGO:0045639430.805
regulation of cytokine productionGO:00018172660.801
regulation of response to biotic stimulusGO:0002831380.800
cell agingGO:0007569350.799
t helper cell differentiationGO:0042093280.798
negative regulation of phosphorus metabolic processGO:00105631840.797
regulation of t helper 2 cell cytokine productionGO:200055130.794
response to dsrnaGO:0043331300.793
cellular response to molecule of fungal originGO:007122620.786
v d j recombinationGO:0033151140.786
myeloid leukocyte activationGO:0002274830.785
positive regulation of acute inflammatory response to antigenic stimulusGO:000286670.780
release of sequestered calcium ion into cytosolGO:0051209420.778
response to oxidative stressGO:00069791230.776
histamine secretion involved in inflammatory responseGO:000244110.776
inflammatory responseGO:00069542440.774
regulation of immunoglobulin secretionGO:0051023120.771
pattern recognition receptor signaling pathwayGO:0002221470.769
protein alkylationGO:0008213810.768
histamine transportGO:005160820.766
somatic recombination of immunoglobulin gene segmentsGO:0016447420.766
skin developmentGO:00435882200.765
regulation of cellular response to stressGO:00801351590.763
b cell apoptotic processGO:0001783190.762
regulation of map kinase activityGO:00434051200.757
spleen developmentGO:0048536390.753
negative regulation of protein phosphorylationGO:00019331260.753
negative regulation of t helper 2 cell differentiationGO:004562940.752
regulation of t cell activationGO:00508631700.752
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.751
negative regulation of b cell mediated immunityGO:000271370.748
positive regulation of chronic inflammatory responseGO:000267840.745
intrinsic apoptotic signaling pathwayGO:00971931320.744
antibacterial peptide productionGO:000277820.740
b cell lineage commitmentGO:000232640.739
positive regulation of protein modification processGO:00314012990.739
negative regulation of molecular functionGO:00440922580.738
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.734
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.732
positive regulation of leukocyte degranulationGO:0043302100.729
alpha beta t cell differentiation involved in immune responseGO:0002293300.726
dephosphorylationGO:00163111290.723
regulation of type ii hypersensitivityGO:000289240.721
positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181220.715
interleukin 12 biosynthetic processGO:004209080.714
azole transportGO:004511760.707
negative regulation of organelle organizationGO:0010639900.704
negative regulation of adaptive immune responseGO:0002820250.702
regulation of humoral immune response mediated by circulating immunoglobulinGO:0002923100.701
regulation of cysteine type endopeptidase activityGO:2000116650.700
apoptotic mitochondrial changesGO:0008637480.698
negative regulation of interleukin 13 secretionGO:200066610.698
regulation of organelle assemblyGO:1902115190.695
regulation of organ morphogenesisGO:20000271440.692
t cell receptor v d j recombinationGO:003315350.690
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.688
positive regulation of humoral immune responseGO:0002922110.687
response to platelet derived growth factorGO:003611960.687
protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:000184440.686
positive regulation of melanocyte differentiationGO:004563650.685
regulation of odontogenesisGO:0042481180.679
covalent chromatin modificationGO:00165691630.678
monocarboxylic acid transportGO:0015718440.676
hair cycleGO:0042633900.674
positive regulation of alpha beta t cell differentiationGO:0046638280.674
regulation of cytoplasmic transportGO:19036491120.674
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.672
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.671
leukocyte apoptotic processGO:0071887710.669
stress activated protein kinase signaling cascadeGO:0031098810.668
positive regulation of interleukin 13 productionGO:003273640.665
regulation of lymphocyte activationGO:00512492400.664
myeloid dendritic cell activationGO:0001773250.664
cytosolic calcium ion homeostasisGO:0051480700.663
positive regulation of mitochondrion organizationGO:0010822170.661
retinal cell programmed cell deathGO:004666680.659
regulation of interleukin 6 productionGO:0032675550.654
positive regulation of fever generationGO:003162260.651
t helper 17 cell differentiationGO:007253970.648
regulation of myeloid leukocyte differentiationGO:0002761580.644
cellular divalent inorganic cation homeostasisGO:00725031270.642
dna alkylationGO:0006305430.637
single organism cell adhesionGO:00986021560.634
regulation of reactive oxygen species metabolic processGO:2000377400.633
regulation of peptidase activityGO:0052547960.631
inflammatory response to antigenic stimulusGO:0002437300.629
activation of innate immune responseGO:0002218560.628
regulation of leukocyte differentiationGO:19021051590.625
regulation of chromosome organizationGO:0033044830.624
regulation of proteolysisGO:00301621640.623
mammary gland lobule developmentGO:0061377220.619
lymphocyte costimulationGO:0031294150.619
histamine secretion by mast cellGO:000255310.618
cellular response to lipidGO:00713961450.617
defense response to bacteriumGO:00427421190.616
calcium ion transport into cytosolGO:0060402480.608
regulation of defense response to virusGO:0050688180.607
immature b cell differentiationGO:0002327100.606
positive regulation of translational initiation by ironGO:004599420.605
t cell apoptotic processGO:0070231390.596
regulation of icosanoid secretionGO:003230380.595
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.593
mapk cascadeGO:00001652810.591
bone resorptionGO:0045453380.590
cellular response to oxidative stressGO:0034599760.586
negative regulation of apoptotic signaling pathwayGO:20012341040.585
nucleocytoplasmic transportGO:00069131390.582
antimicrobial peptide biosynthetic processGO:000277720.581
regulation of t cell proliferationGO:0042129920.581
divalent metal ion transportGO:00708381720.577
positive regulation of apoptotic signaling pathwayGO:2001235950.577
protein homooligomerizationGO:0051260430.567
toll like receptor 4 signaling pathwayGO:003414290.564
positive regulation of hydrolase activityGO:00513451480.558
erk1 and erk2 cascadeGO:0070371770.558
isotype switchingGO:0045190360.552
cellular amino acid metabolic processGO:00065201030.550
leukocyte homeostasisGO:0001776790.549
carboxylic acid transportGO:00469421000.548
positive regulation of calcium ion transport into cytosolGO:001052490.543
symbiosis encompassing mutualism through parasitismGO:0044403830.543
regulation of interleukin 6 biosynthetic processGO:0045408110.542
osteoclast differentiationGO:0030316620.538
cytokine secretion involved in immune responseGO:000237460.535
negative regulation of protein modification processGO:00314001630.534
negative regulation of intracellular signal transductionGO:19025321670.534
regulation of humoral immune responseGO:0002920220.532
regulation of membrane potentialGO:00423911920.532
regulation of metal ion transportGO:00109591060.530
regulation of antibacterial peptide biosynthetic processGO:000280810.528
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.525
regulation of protein homooligomerizationGO:003246230.525
cytokine biosynthetic processGO:0042089680.524
regulation of dendritic cell apoptotic processGO:200066830.522
regulation of adaptive immune responseGO:0002819900.516
response to starvationGO:0042594650.507
positive regulation of calcium ion transportGO:0051928270.507
cellular ketone metabolic processGO:0042180840.502
regulation of mitochondrion organizationGO:0010821270.502
glial cell developmentGO:0021782540.502
calcium ion homeostasisGO:00550741270.498
negative regulation of protein metabolic processGO:00512482820.492
negative regulation of interleukin 13 productionGO:003269620.490
response to retinoic acidGO:0032526560.489
positive regulation of cellular amino acid metabolic processGO:004576430.488
multicellular organismal response to stressGO:0033555620.486
negative regulation of lymphocyte proliferationGO:0050672450.486
regulation of inflammatory responseGO:00507271470.485
regulation of type i hypersensitivityGO:000181040.481
regulation of killing of cells of other organismGO:005170940.480
cellular response to abiotic stimulusGO:0071214560.480
glycerolipid metabolic processGO:00464861220.474
icosanoid transportGO:0071715140.473
detection of mechanical stimulus involved in sensory perception of painGO:005096640.468
regulation of ceramide biosynthetic processGO:200030310.466
cellular response to organonitrogen compoundGO:00714171450.466
mitochondrial outer membrane permeabilization involved in programmed cell deathGO:1902686110.460
positive regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902110110.458
antibacterial humoral responseGO:001973180.455
endodermal cell fate specificationGO:000171440.454
mammary gland epithelial cell proliferationGO:0033598240.454
mucosal associated lymphoid tissue developmentGO:0048537120.454
regulation of nuclear divisionGO:0051783560.453
positive regulation of b cell mediated immunityGO:0002714260.448
negative regulation of lymphocyte activationGO:0051250910.448
peptidyl amino acid modificationGO:00181933360.448
cellular response to acid chemicalGO:0071229680.444
cellular response to cytokine stimulusGO:00713451890.443
regulation of type iia hypersensitivityGO:000179640.438
regulation of antimicrobial peptide productionGO:000278410.438
regulation of neuron differentiationGO:00456642810.429
negative regulation of t cell differentiationGO:0045581230.428
reactive oxygen species metabolic processGO:0072593840.428
protein modification by small protein conjugation or removalGO:00706472070.427
phosphatidylinositol 3 phosphate biosynthetic processGO:003609260.422
cellular process regulating host cell cycle in response to virusGO:006015430.422
positive regulation of mitochondrial membrane permeabilityGO:0035794120.421
positive regulation of map kinase activityGO:0043406840.421
positive regulation of jnk cascadeGO:0046330460.420
developmental programmed cell deathGO:0010623410.419
aromatic compound catabolic processGO:00194392860.418
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.417
regulation of defense responseGO:00313472330.413
positive regulation of chronic inflammatory response to antigenic stimulusGO:000287620.409
negative regulation of myeloid leukocyte differentiationGO:0002762200.405
cellular response to inorganic substanceGO:0071241370.403
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217590.402
response to organonitrogen compoundGO:00102432460.400
positive regulation of interleukin 6 productionGO:0032755370.400
t helper 17 type immune responseGO:007253890.399
protein methylationGO:0006479810.398
regionalizationGO:00030023370.397
negative regulation of phosphorylationGO:00423261660.396
photoreceptor cell differentiationGO:0046530520.395
positive regulation of interleukin 3 productionGO:003275220.392
positive regulation of myeloid leukocyte differentiationGO:0002763260.390
multicellular organism growthGO:00352641610.387
regulation of cytokine production involved in immune responseGO:0002718260.387
cellular response to amino acid stimulusGO:0071230290.387
dna damage checkpointGO:0000077260.382
telencephalon developmentGO:00215371860.380
granulocyte macrophage colony stimulating factor biosynthetic processGO:004225320.380
cytoplasmic transportGO:00164822340.376
hemostasisGO:0007599780.374
regulation of skeletal muscle fiber developmentGO:0048742360.373
glycolipid metabolic processGO:0006664250.373
macromolecule catabolic processGO:00090572810.372
intracellular receptor signaling pathwayGO:0030522740.370
response to organic cyclic compoundGO:00140701980.370
cell type specific apoptotic processGO:00972852680.369
negative regulation of humoral immune response mediated by circulating immunoglobulinGO:000292430.364
icosanoid secretionGO:0032309120.364
regulation of myeloid leukocyte mediated immunityGO:0002886250.363
negative regulation of protein processingGO:0010955790.362
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.361
mitochondrion organizationGO:00070051340.359
response to uv bGO:001022450.356
negative regulation of hydrolase activityGO:0051346710.353
cellular response to tumor necrosis factorGO:0071356210.352
epidermis developmentGO:00085441870.352
regulation of peptidyl tyrosine phosphorylationGO:0050730930.350
negative regulation of gene expression epigeneticGO:0045814150.348
protein acylationGO:0043543640.347
cellular ion homeostasisGO:00068731650.347
dna repairGO:00062811070.342
extracellular matrix organizationGO:00301981470.337
regulation of cytokine secretion involved in immune responseGO:000273940.336
g1 s transition of mitotic cell cycleGO:0000082570.336
regulation of organelle organizationGO:00330432890.332
regulation of t helper 17 cell differentiationGO:200031920.330
neuron apoptotic processGO:00514021420.327
nitrogen compound transportGO:00717052710.327
salivary gland developmentGO:0007431370.327
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.326
acid secretionGO:0046717330.325
organic anion transportGO:00157111370.325
negative regulation of cell proliferationGO:00082852960.324
negative regulation of cysteine type endopeptidase activityGO:2000117220.324
regulation of mammary gland involutionGO:190351940.323
protein autophosphorylationGO:0046777610.323
regulation of mast cell degranulationGO:0043304160.323
regulation of mitotic cell cycleGO:00073461260.320
eye photoreceptor cell differentiationGO:0001754410.320
positive regulation of protein phosphorylationGO:00019342420.320
positive regulation of organelle organizationGO:00106381280.319
positive regulation of nervous system developmentGO:00519622210.319
production of molecular mediator of immune responseGO:00024401030.318
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.315
response to tumor necrosis factorGO:0034612260.315
regulation of protein complex assemblyGO:0043254830.312
regulation of lymphocyte apoptotic processGO:0070228410.311
chronic inflammatory responseGO:000254490.308
regulation of defense response to virus by hostGO:005069180.307
fever generationGO:000166070.302
regulation of antimicrobial humoral responseGO:000275930.299
myeloid leukocyte differentiationGO:00025731190.298
regulation of protein serine threonine kinase activityGO:00719001570.298
cerebral cortex developmentGO:0021987860.296
t cell mediated immunityGO:0002456500.295
myeloid cell differentiationGO:00300992330.294
negative regulation of regulatory t cell differentiationGO:004559020.293
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.289
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.289
regulation of histone modificationGO:0031056560.284
positive regulation of kinase activityGO:00336741550.284
positive regulation of transferase activityGO:00513471670.283
regulation of protein localizationGO:00328802310.282
response to hypoxiaGO:0001666580.282
posttranscriptional regulation of gene expressionGO:00106081550.282
negative regulation of cellular amino acid metabolic processGO:004576300.281
regulation of type i interferon productionGO:0032479220.281
monosaccharide transportGO:0015749580.276
positive regulation of cell activationGO:00508671580.275
regulation of striated muscle cell differentiationGO:0051153810.274
response to acid chemicalGO:00011011110.274
positive regulation of response to woundingGO:1903036660.269
positive regulation of lymphocyte apoptotic processGO:0070230130.268
negative regulation of cellular protein metabolic processGO:00322692470.267
platelet aggregationGO:0070527200.267
regulation of hydrolase activityGO:00513362460.264
positive regulation of response to biotic stimulusGO:0002833150.263
regulation of jnk cascadeGO:0046328620.263
epithelial tube morphogenesisGO:00605623030.262
cellular response to starvationGO:0009267570.262
positive regulation of b cell receptor signaling pathwayGO:005086140.261
negative regulation of cell agingGO:009034450.261
positive regulation of histone deacetylationGO:003106570.257
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.256
protein activation cascadeGO:0072376190.254
ensheathment of neuronsGO:0007272760.252
negative regulation of protein catabolic processGO:0042177360.249
cellular response to nutrient levelsGO:0031669640.248
regulation of protein maturationGO:1903317960.246
positive regulation of acute inflammatory responseGO:0002675160.245
positive regulation of stress activated mapk cascadeGO:0032874480.244
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathwayGO:190337630.243
phospholipid catabolic processGO:000939550.243
regulation of innate immune responseGO:0045088910.243
positive regulation of proteolysisGO:0045862850.242
regulation of myeloid cell differentiationGO:0045637960.242
positive regulation of defense response to bacteriumGO:190042610.241
branching involved in mammary gland duct morphogenesisGO:0060444270.238
protein catabolic processGO:00301632210.238
positive regulation of jun kinase activityGO:0043507300.236
negative regulation of odontogenesis of dentin containing toothGO:004248910.236
regulation of multi organism processGO:00439001110.234
maturation of ssu rrnaGO:003049010.233
positive regulation of osteoclast differentiationGO:0045672150.233
hepaticobiliary system developmentGO:0061008670.232
odontogenesisGO:0042476780.231
nuclear importGO:0051170950.231
endoplasmic reticulum calcium ion homeostasisGO:0032469110.229
positive regulation of translationGO:0045727190.228
regulation of erythrocyte differentiationGO:0045646230.227
positive regulation of lymphocyte activationGO:00512511400.226
cellular response to gamma radiationGO:007148040.226

Igh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
primary immunodeficiency diseaseDOID:61201.000
blood protein diseaseDOID:62001.000
immune system diseaseDOID:291401.000
agammaglobulinemiaDOID:258301.000
disease of anatomical entityDOID:701.000
common variable immunodeficiencyDOID:1217701.000
b cell deficiencyDOID:211501.000
hematopoietic system diseaseDOID:7401.000