Mus musculus

74 known processes

Ikbkb

inhibitor of kappaB kinase beta

(Aliases: IKK-2,IKKbeta,IKK2,IKK-beta,AI132552,IKK[b])

Ikbkb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
activation of nf kappab inducing kinase activityGO:000725041.000
antibacterial peptide productionGO:000277820.999
Fly
positive regulation of antibacterial peptide biosynthetic processGO:000696310.999
Fly
positive regulation of antimicrobial humoral responseGO:000276020.993
Fly
regulation of defense response to bacteriumGO:190042430.991
Fly
positive regulation of defense response to bacteriumGO:190042610.990
Fly
antimicrobial peptide biosynthetic processGO:000277720.984
Fly
i kappab phosphorylationGO:000725260.980
regulation of antibacterial peptide biosynthetic processGO:000280810.973
Fly
i kappab kinase nf kappab signalingGO:0007249850.970
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.969
Fly
regulation of antimicrobial humoral responseGO:000275930.967
Fly
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.963
antimicrobial peptide productionGO:000277520.942
Fly
negative regulation of necrotic cell deathGO:0060547110.934
interferon beta biosynthetic processGO:004535040.929
Mouse
apoptotic signaling pathwayGO:00971903060.921
regulation of defense responseGO:00313472330.917
Mouse Fly
regulation of necrotic cell deathGO:0010939130.915
regulation of necroptotic processGO:0060544100.908
ripoptosome assembly involved in necroptotic processGO:190102660.874
regulation of antibacterial peptide productionGO:000278610.873
Fly
activation of immune responseGO:00022531380.873
Mouse
positive regulation of interferon beta productionGO:003272880.863
Mouse
positive regulation of cytokine productionGO:00018191740.858
Mouse
regulation of antimicrobial peptide productionGO:000278410.850
Fly
cytokine biosynthetic processGO:0042089680.848
Mouse
peptide metabolic processGO:0006518460.836
Fly
regulation of establishment of protein localizationGO:00702011810.833
necroptotic processGO:0070266210.811
defense response to bacteriumGO:00427421190.810
Mouse Fly
programmed necrotic cell deathGO:0097300280.806
protein modification by small protein conjugationGO:00324461870.771
positive regulation of innate immune responseGO:0045089800.759
Mouse
cellular response to dna damage stimulusGO:00069742070.758
dna metabolic processGO:00062593030.752
intrinsic apoptotic signaling pathwayGO:00971931320.751
negative regulation of apoptotic signaling pathwayGO:20012341040.748
innate immune responseGO:00450871570.739
Mouse Fly
type i interferon biosynthetic processGO:004535190.730
Mouse
positive regulation of humoral immune responseGO:0002922110.728
Fly
defense response to other organismGO:00985421970.726
Mouse Fly
nik nf kappab signalingGO:0038061140.723
protein modification by small protein conjugation or removalGO:00706472070.722
response to endoplasmic reticulum stressGO:0034976530.713
negative regulation of intracellular signal transductionGO:19025321670.703
negative regulation of necroptotic processGO:006054690.696
negative regulation of molecular functionGO:00440922580.690
intracellular protein transportGO:00068862040.685
regulation of defense response to virusGO:0050688180.684
Fly
regulation of apoptotic signaling pathwayGO:20012331970.679
activation of innate immune responseGO:0002218560.669
Mouse
cellular amide metabolic processGO:0043603580.640
Fly
regulation of nik nf kappab signalingGO:1901222100.630
cellular protein catabolic processGO:00442571550.629
leukocyte differentiationGO:00025213420.623
Mouse
establishment of protein localization to organelleGO:00725941180.612
positive regulation of antimicrobial peptide productionGO:000222510.611
Fly
regulation of cytokine biosynthetic processGO:0042035590.607
Mouse
positive regulation of protein phosphorylationGO:00019342420.601
myeloid cell differentiationGO:00300992330.594
Mouse
b cell homeostasisGO:0001782340.594
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.587
Human Rat
protein importGO:00170381010.580
regulation of protein kinase activityGO:00458592320.573
lymphocyte differentiationGO:00300982420.571
regulation of protein localizationGO:00328802310.557
skeletal system developmentGO:00015013560.555
regulation of multi organism processGO:00439001110.548
Fly
positive regulation of sodium ion transportGO:0010765130.548
positive regulation of cytokine biosynthetic processGO:0042108400.530
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.494
homeostasis of number of cellsGO:00488722100.481
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.471
regulation of transferase activityGO:00513382630.469
negative regulation of response to endoplasmic reticulum stressGO:190357380.467
leukocyte proliferationGO:00706611720.461
Mouse
cellular response to lipopolysaccharideGO:0071222770.451
positive regulation of defense responseGO:00313491240.451
Mouse Fly
myeloid leukocyte differentiationGO:00025731190.444
Mouse
protein import into nucleusGO:0006606950.444
positive regulation of production of molecular mediator of immune responseGO:0002702450.439
Fly
cytokine productionGO:00018163190.436
Mouse
positive regulation of kinase activityGO:00336741550.422
regulation of reactive oxygen species metabolic processGO:2000377400.422
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.421
positive regulation of protein serine threonine kinase activityGO:00719021060.411
regulation of kinase activityGO:00435492490.405
response to molecule of bacterial originGO:00022371430.400
cellular response to cytokine stimulusGO:00713451890.398
Human
antibacterial peptide biosynthetic processGO:000278020.394
Fly
immune effector processGO:00022523210.394
Fly
cellular response to molecule of bacterial originGO:0071219830.393
protein ubiquitinationGO:00165671710.382
lymphocyte activation involved in immune responseGO:0002285930.382
humoral immune responseGO:0006959570.380
Fly
reactive oxygen species metabolic processGO:0072593840.374
positive regulation of nik nf kappab signalingGO:190122470.371
positive regulation of proteolysisGO:0045862850.364
regulation of intracellular protein transportGO:0033157820.362
mitochondrion organizationGO:00070051340.361
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.358
modification dependent macromolecule catabolic processGO:00436321330.355
t cell activationGO:00421102890.352
regulation of innate immune responseGO:0045088910.350
Mouse Fly
response to lipopolysaccharideGO:00324961280.350
mammary gland epithelial cell proliferationGO:0033598240.343
Mouse
positive regulation of apoptotic processGO:00430652170.342
production of molecular mediator of immune responseGO:00024401030.339
Fly
macromolecule catabolic processGO:00090572810.338
Fly
negative regulation of defense responseGO:0031348770.337
regulation of sequence specific dna binding transcription factor activityGO:00510901060.336
Human Rat
organonitrogen compound biosynthetic processGO:19015661920.335
Fly
regulation of map kinase activityGO:00434051200.334
regulation of cytokine productionGO:00018172660.327
Mouse
covalent chromatin modificationGO:00165691630.325
proteolysis involved in cellular protein catabolic processGO:00516031470.323
t cell activation involved in immune responseGO:0002286430.323
immunoglobulin mediated immune responseGO:0016064690.309
glycosyl compound metabolic processGO:19016572460.307
leukocyte activation involved in immune responseGO:00023661260.303
regulation of interferon gamma productionGO:0032649570.299
regulation of defense response to virus by hostGO:005069180.296
Fly
cell activation involved in immune responseGO:00022631260.295
nucleocytoplasmic transportGO:00069131390.290
muscle cell differentiationGO:00426922610.290
neuron deathGO:00709971540.286
Rat
cytoplasmic transportGO:00164822340.284
lipopolysaccharide mediated signaling pathwayGO:0031663250.279
cellular amino acid metabolic processGO:00065201030.277
lymphocyte mediated immunityGO:00024491390.276
regulation of cellular amino acid metabolic processGO:000652150.274
regulation of protein serine threonine kinase activityGO:00719001570.267
muscle tissue developmentGO:00605373080.266
cell type specific apoptotic processGO:00972852680.265
positive regulation of peptidase activityGO:0010952490.265
regulation of protein targetingGO:1903533610.262
protein maturationGO:00516041760.259
engulfment of apoptotic cellGO:004365230.258
regulation of transcription factor import into nucleusGO:0042990240.253
cellular response to lipidGO:00713961450.250
mammary gland epithelium developmentGO:0061180650.244
Mouse
neural tube developmentGO:00219151600.243
regulation of protein complex assemblyGO:0043254830.242
negative regulation of cellular component organizationGO:00511291940.242
nuclear transportGO:00511691390.240
modification dependent protein catabolic processGO:00199411330.238
type i interferon productionGO:0032606290.236
Mouse
phagocytosisGO:0006909660.235
regulation of intracellular transportGO:00323861590.234
protein localization to nucleusGO:00345041210.229
positive regulation of protein modification processGO:00314012990.226
bone developmentGO:00603481200.226
regulation of cell motilityGO:20001452360.225
cellular response to growth factor stimulusGO:00713631970.224
positive regulation of immune effector processGO:00026991070.218
Fly
immune response activating signal transductionGO:00027571160.210
peptidyl amino acid modificationGO:00181933360.208
Human Fly
compound eye developmentGO:004874910.206
response to organic cyclic compoundGO:00140701980.205
embryonic skeletal system developmentGO:00487061200.205
activation of jnkk activityGO:000725630.204
protein polyubiquitinationGO:0000209330.204
regulation of neuron projection developmentGO:00109751690.203
regulation of endopeptidase activityGO:0052548890.202
regulation of protein import into nucleusGO:0042306520.202
regulation of cellular response to stressGO:00801351590.202
positive regulation of protein import into nucleusGO:0042307260.201
ripoptosome assemblyGO:009734360.197
positive regulation of protein localization to nucleusGO:1900182300.197
peptidyl serine modificationGO:0018209830.196
Human Fly
negative regulation of immune system processGO:00026832090.195
regulation of cellular amine metabolic processGO:0033238200.195
regulation of nucleocytoplasmic transportGO:0046822730.192
positive regulation of nf kappab transcription factor activityGO:0051092300.191
Human Rat
regulation of hydrolase activityGO:00513362460.189
ubiquitin dependent protein catabolic processGO:00065111290.189
heterocycle catabolic processGO:00467002800.189
tumor necrosis factor superfamily cytokine productionGO:0071706510.187
positive regulation of intracellular protein transportGO:0090316420.186
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.186
embryonic organ morphogenesisGO:00485622760.186
positive regulation of interferon beta biosynthetic processGO:004535930.185
Mouse
myeloid dendritic cell activationGO:0001773250.184
activation of mapk activityGO:0000187590.183
regulation of neuron differentiationGO:00456642810.181
positive regulation of lymphocyte mediated immunityGO:0002708620.179
mitotic cell cycleGO:00002781950.178
aromatic compound catabolic processGO:00194392860.178
positive regulation of transferase activityGO:00513471670.176
response to oxidative stressGO:00069791230.176
negative regulation of cellular amino acid metabolic processGO:004576300.175
organelle fusionGO:0048284280.172
spermatogenesisGO:00072832840.171
protein localization to organelleGO:00333651850.169
protein processingGO:00164851630.168
negative regulation of protein modification processGO:00314001630.167
angiogenesisGO:00015252010.167
digestive system developmentGO:00551232000.165
neurotransmitter transportGO:0006836760.165
regulation of humoral immune responseGO:0002920220.165
Fly
regulation of peptidyl tyrosine phosphorylationGO:0050730930.163
organelle fissionGO:00482851700.163
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.161
male gamete generationGO:00482322850.160
ossificationGO:00015032160.159
epithelial cell proliferationGO:00506731740.158
Mouse
b cell mediated immunityGO:0019724710.158
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.158
positive regulation of protein kinase activityGO:00458601440.153
cytokine production involved in immune responseGO:0002367340.151
positive regulation of response to biotic stimulusGO:0002833150.151
Fly
regulation of cellular amide metabolic processGO:0034248100.151
Fly
cell divisionGO:00513011200.148
anatomical structure homeostasisGO:00602491450.147
chemotaxisGO:00069352470.145
cellular response to tumor necrosis factorGO:0071356210.144
Human
cellular macromolecule catabolic processGO:00442652060.143
negative regulation of myeloid cell differentiationGO:0045638380.143
positive regulation of cysteine type endopeptidase activityGO:2001056390.142
synaptic vesicle localizationGO:0097479590.141
epithelial tube morphogenesisGO:00605623030.141
negative regulation of reactive oxygen species metabolic processGO:2000378100.141
stress activated protein kinase signaling cascadeGO:0031098810.141
peptidyl tyrosine modificationGO:00182121450.140
regulation of response to biotic stimulusGO:0002831380.139
Fly
negative regulation of inflammatory responseGO:0050728610.139
response to tumor necrosis factorGO:0034612260.137
Human
positive regulation of apoptotic signaling pathwayGO:2001235950.136
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.135
vesicle localizationGO:0051648860.134
purine ribonucleotide metabolic processGO:00091502900.133
germ cell developmentGO:00072811850.132
proteasomal protein catabolic processGO:0010498980.132
regulation of neuron apoptotic processGO:00435231220.132
negative regulation of transferase activityGO:0051348850.131
organonitrogen compound catabolic processGO:19015652640.130
cytokine mediated signaling pathwayGO:00192211150.128
protein targetingGO:00066051430.128
amine metabolic processGO:0009308450.125
cellular protein complex assemblyGO:00436231160.125
purine ribonucleoside catabolic processGO:00461302050.125
morphogenesis of an epithelial sheetGO:0002011270.125
Mouse
negative regulation of cellular amine metabolic processGO:003323910.125
axonogenesisGO:00074092740.124
muscle cell developmentGO:00550011330.124
extracellular structure organizationGO:00430621480.122
t cell differentiationGO:00302171740.122
gland developmentGO:00487323300.121
Mouse
cellular response to transforming growth factor beta stimulusGO:0071560880.120
vacuole organizationGO:0007033380.120
execution phase of apoptosisGO:0097194190.119
embryonic epithelial tube formationGO:00018381300.119
positive regulation of type i interferon productionGO:0032481140.118
Mouse
gtp metabolic processGO:00460391440.117
positive regulation of cellular amine metabolic processGO:003324050.116
vesicle fusionGO:0006906160.116
positive regulation of myeloid leukocyte differentiationGO:0002763260.115
negative regulation of intracellular protein transportGO:0090317270.115
regulation of cell migrationGO:00303342190.115
cellular nitrogen compound catabolic processGO:00442702800.114
necrotic cell deathGO:0070265300.114
regulation of cysteine type endopeptidase activityGO:2000116650.112
lymphocyte proliferationGO:00466511640.111
Mouse
regulation of neurotransmitter levelsGO:0001505870.111
purine nucleoside catabolic processGO:00061522050.110
membrane organizationGO:00610242450.110
ribonucleoside catabolic processGO:00424542060.110
interferon beta productionGO:0032608160.110
Mouse
negative regulation of nf kappab transcription factor activityGO:0032088150.110
skeletal muscle organ developmentGO:00605381630.109
epidermis developmentGO:00085441870.109
gonad developmentGO:00084061410.108
nuclear importGO:0051170950.106
defense response to gram positive bacteriumGO:0050830500.106
Mouse
lactationGO:0007595250.105
Mouse
organic cyclic compound catabolic processGO:19013612950.105
regulation of cell projection organizationGO:00313442060.105
regulation of ripoptosome assembly involved in necroptotic processGO:190244230.104
peptidyl serine phosphorylationGO:0018105740.104
Human Fly
positive regulation of protein complex assemblyGO:0031334450.104
regulation of neuron deathGO:19012141340.104
Rat
regulation of mapk cascadeGO:00434082480.104
transmembrane transportGO:00550854120.104
regulation of cellular catabolic processGO:00313292420.103
glial cell apoptotic processGO:003434930.103
muscle contractionGO:00069361010.102
Rat
regulation of jun kinase activityGO:0043506400.102
regulation of peptide transportGO:0090087910.101
histone modificationGO:00165701590.100
rhythmic processGO:00485111740.100
nitrogen compound transportGO:00717052710.099
positive regulation of ion transmembrane transporter activityGO:0032414150.098
peptidyl tyrosine phosphorylationGO:00181081430.098
negative regulation of protein metabolic processGO:00512482820.097
somitogenesisGO:0001756690.097
positive regulation of programmed cell deathGO:00430682180.097
skin developmentGO:00435882200.097
blood vessel morphogenesisGO:00485142850.095
regulation of cytoplasmic transportGO:19036491120.094
t helper cell differentiationGO:0042093280.094
synaptic transmissionGO:00072683290.094
regulation of ossificationGO:00302781120.093
spleen developmentGO:0048536390.092
morphogenesis of embryonic epitheliumGO:00163311590.092
axon guidanceGO:00074111410.092
regulation of membrane potentialGO:00423911920.092
positive regulation of intracellular transportGO:0032388700.091
positive regulation of cytokine production involved in immune responseGO:0002720190.091
positive regulation of mapk cascadeGO:00434101700.090
regulation of ion transportGO:00432692150.090
embryonic skeletal system morphogenesisGO:0048704910.089
ribonucleoside metabolic processGO:00091192450.089
b cell activationGO:00421131610.089
internal peptidyl lysine acetylationGO:0018393420.088
regulation of inflammatory responseGO:00507271470.088
regulation of peptidase activityGO:0052547960.087
activation of cysteine type endopeptidase activityGO:0097202270.087
sensory organ morphogenesisGO:00905962420.086
hair cycleGO:0042633900.086
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.086
negative regulation of interleukin 6 productionGO:0032715170.086
positive regulation of jun kinase activityGO:0043507300.086
regulation of organelle organizationGO:00330432890.086
ion transmembrane transportGO:00342203610.085
neuron migrationGO:00017641220.085
activation of mapkk activityGO:0000186150.085
positive regulation of cellular catabolic processGO:00313311480.085
skeletal system morphogenesisGO:00487052030.085
purine nucleoside metabolic processGO:00422782410.085
digestive tract morphogenesisGO:00485461470.083
regulation of ion transmembrane transporter activityGO:0032412540.082
nuclear divisionGO:00002801580.082
tumor necrosis factor mediated signaling pathwayGO:0033209130.082
vesicle organizationGO:0016050600.081
neuron apoptotic processGO:00514021420.081
positive regulation of endopeptidase activityGO:0010950430.081
alpha beta t cell activationGO:0046631910.081
positive regulation of ion transportGO:0043270650.080
cd4 positive alpha beta t cell differentiationGO:0043367410.080
purine nucleotide metabolic processGO:00061633020.079
negative regulation of lymphocyte activationGO:0051250910.079
negative regulation of wnt signaling pathwayGO:0030178730.078
digestive tract developmentGO:00485651900.078
tumor necrosis factor productionGO:0032640500.078
purine nucleoside triphosphate catabolic processGO:00091462030.077
positive regulation of interleukin 2 productionGO:0032743190.077
nucleoside catabolic processGO:00091642060.076
regulation of interferon beta biosynthetic processGO:004535740.076
Mouse
protein catabolic processGO:00301632210.075
Fly
ribonucleoside triphosphate catabolic processGO:00092031990.075
positive regulation of secretionGO:00510471300.075
ribonucleotide metabolic processGO:00092592910.075
synaptic vesicle transportGO:0048489570.075
response to acid chemicalGO:00011011110.075
Rat
regulation of cellular component biogenesisGO:00440871810.075
membrane fusionGO:0061025380.075
appendage morphogenesisGO:00351071490.074
alpha beta t cell differentiationGO:0046632690.073
nucleoside triphosphate metabolic processGO:00091412300.073
segment specificationGO:0007379150.073
neural tube formationGO:00018411080.073
single organism nuclear importGO:1902593950.072
nucleotide catabolic processGO:00091662170.072
regulation of cation channel activityGO:2001257220.072
regulation of protein maturationGO:1903317960.071
striated muscle cell developmentGO:00550021250.071
regulation of jnk cascadeGO:0046328620.071
negative regulation of cell developmentGO:00107211690.071
chromatin organizationGO:00063252060.071
ensheathment of neuronsGO:0007272760.071
regulation of protein localization to nucleusGO:1900180600.070
response to muramyl dipeptideGO:003249590.070
tube formationGO:00351481400.070
regulation of tumor necrosis factor productionGO:0032680490.069
zymogen activationGO:0031638410.069
dephosphorylationGO:00163111290.068
purine ribonucleoside triphosphate metabolic processGO:00092052200.068
regulation of bindingGO:00510981110.068
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.068
antigen receptor mediated signaling pathwayGO:0050851640.068
regulation of proteolysisGO:00301621640.068
purine containing compound metabolic processGO:00725213110.067
cellular response to biotic stimulusGO:0071216920.067
response to amino acidGO:0043200370.066
negative regulation of protein transportGO:0051224460.066
regulation of protein bindingGO:0043393600.066
striated muscle tissue developmentGO:00147062930.066
mapk cascadeGO:00001652810.066
regulation of cytokine production involved in immune responseGO:0002718260.066
regulation of body fluid levelsGO:00508781620.065
Mouse
carbohydrate derivative catabolic processGO:19011362310.065
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.065
negative regulation of protein phosphorylationGO:00019331260.065
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.064
extrinsic apoptotic signaling pathwayGO:00971911260.064
purine containing compound catabolic processGO:00725232130.064
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.064
ribonucleotide catabolic processGO:00092612080.064
organelle localizationGO:00516401790.062
maintenance of locationGO:0051235890.062
leukocyte mediated immunityGO:00024431740.062
lymphocyte homeostasisGO:0002260640.062
blood coagulationGO:0007596760.062
osteoclast differentiationGO:0030316620.061
Mouse
regulation of protein secretionGO:0050708820.061
positive regulation of neuron differentiationGO:00456661410.061
positive regulation of angiogenesisGO:0045766460.060
regulation of adaptive immune responseGO:0002819900.060
regionalizationGO:00030023370.060
positive regulation of cell developmentGO:00107202370.060
positive regulation of map kinase activityGO:0043406840.060
cellular response to organic cyclic compoundGO:0071407870.060
gtp catabolic processGO:00061841430.060
regulation of cell cycle processGO:00105641600.060
negative regulation of proteolysisGO:0045861740.060
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.059
regulation of protein transportGO:00512231630.059
regulation of transporter activityGO:0032409570.059
histone acetylationGO:0016573410.059
pattern recognition receptor signaling pathwayGO:0002221470.058
positive regulation of organelle organizationGO:00106381280.058
nucleotide metabolic processGO:00091173320.058
odontogenesisGO:0042476780.058
Mouse
regulation of lymphocyte mediated immunityGO:0002706840.058
multicellular organismal homeostasisGO:00488711640.057
positive regulation of nervous system developmentGO:00519622210.057
regulation of cell cycleGO:00517262810.057
intracellular receptor signaling pathwayGO:0030522740.057
cellularizationGO:000734910.057
fibroblast proliferationGO:0048144350.057
oogenesisGO:0048477560.057
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.056
protein oligomerizationGO:0051259670.056
microtubule cytoskeleton organizationGO:00002261570.056
embryonic placenta developmentGO:0001892980.055
amide transportGO:00428861380.055
glial cell differentiationGO:00100011310.055
adaptive immune responseGO:00022501550.055
negative regulation of cell proliferationGO:00082852960.055
chromatin modificationGO:00165681870.054
innate immune response activating signal transductionGO:0002758500.054
cytokine metabolic processGO:0042107710.054
Mouse
regulation of stress activated mapk cascadeGO:0032872690.054
hair follicle developmentGO:0001942850.054
protein homooligomerizationGO:0051260430.054
t cell mediated immunityGO:0002456500.054
pigment metabolic processGO:0042440320.053
regulation of purine nucleotide metabolic processGO:19005421690.053
b cell activation involved in immune responseGO:0002312500.053
extracellular matrix organizationGO:00301981470.053
respiratory tube developmentGO:00303231670.053
positive regulation of cellular component biogenesisGO:0044089940.053
ribonucleoside triphosphate metabolic processGO:00091992200.053
positive regulation of growthGO:00459271040.052
determination of left right symmetryGO:0007368800.052
cellular homeostasisGO:00197252400.052
regulation of canonical wnt signaling pathwayGO:0060828820.051
regulation of production of molecular mediator of immune responseGO:0002700650.051
Fly
germinal center formationGO:0002467160.051
odontogenesis of dentin containing toothGO:0042475660.051
Mouse
regulation of cytoskeleton organizationGO:00514931220.051
regulation of leukocyte proliferationGO:00706631210.050
neurotransmitter secretionGO:0007269620.050
development of primary sexual characteristicsGO:00451371430.050
cd4 positive alpha beta t cell activationGO:0035710450.050
cellular amine metabolic processGO:0044106440.050
internal protein amino acid acetylationGO:0006475420.050
glycosyl compound catabolic processGO:19016582060.049
myeloid cell homeostasisGO:00022621140.049
purine nucleoside triphosphate metabolic processGO:00091442260.049
regulation of wnt signaling pathwayGO:00301111230.049
regulation of myeloid cell differentiationGO:0045637960.049
immunoglobulin productionGO:0002377730.049
negative regulation of cytokine productionGO:0001818840.048
gastrulationGO:00073691160.048
myeloid dendritic cell differentiationGO:0043011160.048
negative regulation of cytoplasmic transportGO:1903650290.048
epithelial tube formationGO:00721751300.048
muscle fiber developmentGO:0048747760.047
mitotic cell cycle processGO:19030471590.047
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.047
regulation of interleukin 10 secretionGO:200117940.047
interferon gamma productionGO:0032609670.047
long term synaptic potentiationGO:0060291250.047
regulation of organ morphogenesisGO:20000271440.047
canonical wnt signaling pathwayGO:00600701300.047
guanosine containing compound catabolic processGO:19010691440.046
jnk cascadeGO:0007254720.046
response to oxygen levelsGO:0070482620.046
positive regulation of t cell cytokine productionGO:000272650.046

Ikbkb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.144
skin diseaseDOID:3700.144
integumentary system diseaseDOID:1600.144
disease of cellular proliferationDOID:1456600.077