| serine phosphorylation of stat protein | GO:0042501 | 3 | 1.000 | |
| positive regulation of antimicrobial peptide production | GO:0002225 | 1 | 1.000 | |
| positive regulation of antibacterial peptide biosynthetic process | GO:0006963 | 1 | 1.000 | |
| antibacterial humoral response | GO:0019731 | 8 | 1.000 | |
| regulation of antibacterial peptide production | GO:0002786 | 1 | 1.000 | |
| negative regulation of necrotic cell death | GO:0060547 | 11 | 1.000 | |
| negative regulation of necroptotic process | GO:0060546 | 9 | 1.000 | |
| positive regulation of interferon beta biosynthetic process | GO:0045359 | 3 | 1.000 | |
| activation of nf kappab inducing kinase activity | GO:0007250 | 4 | 1.000 | |
| regulation of antibacterial peptide biosynthetic process | GO:0002808 | 1 | 1.000 | |
| antibacterial peptide production | GO:0002778 | 2 | 1.000 | |
| i kappab phosphorylation | GO:0007252 | 6 | 1.000 | Zebrafish |
| regulation of defense response to bacterium | GO:1900424 | 3 | 1.000 | |
| ripoptosome assembly involved in necroptotic process | GO:1901026 | 6 | 1.000 | |
| interferon beta biosynthetic process | GO:0045350 | 4 | 1.000 | |
| negative regulation of ripoptosome assembly involved in necroptotic process | GO:1902443 | 3 | 0.999 | |
| antibacterial peptide biosynthetic process | GO:0002780 | 2 | 0.999 | |
| regulation of interferon beta biosynthetic process | GO:0045357 | 4 | 0.999 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.999 | Human Zebrafish |
| positive regulation of defense response to bacterium | GO:1900426 | 1 | 0.998 | |
| positive regulation of antibacterial peptide production | GO:0002803 | 1 | 0.997 | |
| antimicrobial peptide production | GO:0002775 | 2 | 0.997 | |
| regulation of necroptotic process | GO:0060544 | 10 | 0.995 | |
| programmed necrotic cell death | GO:0097300 | 28 | 0.993 | |
| dendritic cell proliferation | GO:0044565 | 2 | 0.989 | |
| positive regulation of antimicrobial peptide biosynthetic process | GO:0002807 | 1 | 0.988 | |
| regulation of antimicrobial humoral response | GO:0002759 | 3 | 0.987 | |
| regulation of antimicrobial peptide biosynthetic process | GO:0002805 | 1 | 0.984 | |
| positive regulation of antimicrobial humoral response | GO:0002760 | 2 | 0.979 | |
| antimicrobial peptide biosynthetic process | GO:0002777 | 2 | 0.975 | |
| regulation of necrotic cell death | GO:0010939 | 13 | 0.974 | |
| regulation of defense response | GO:0031347 | 233 | 0.970 | |
| necroptotic process | GO:0070266 | 21 | 0.969 | |
| activation of innate immune response | GO:0002218 | 56 | 0.962 | |
| interferon beta production | GO:0032608 | 16 | 0.949 | |
| positive regulation of production of molecular mediator of immune response | GO:0002702 | 45 | 0.911 | |
| defense response to virus | GO:0051607 | 68 | 0.908 | |
| regulation of defense response to virus by host | GO:0050691 | 8 | 0.900 | |
| cellular amide metabolic process | GO:0043603 | 58 | 0.898 | |
| regulation of ripoptosome assembly involved in necroptotic process | GO:1902442 | 3 | 0.885 | |
| peptide metabolic process | GO:0006518 | 46 | 0.863 | |
| positive regulation of defense response to virus by host | GO:0002230 | 6 | 0.860 | |
| innate immune response | GO:0045087 | 157 | 0.860 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.857 | |
| positive regulation of innate immune response | GO:0045089 | 80 | 0.852 | |
| defense response to bacterium | GO:0042742 | 119 | 0.850 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 54 | 0.849 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.829 | |
| regulation of antimicrobial peptide production | GO:0002784 | 1 | 0.828 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.827 | |
| regulation of interferon beta production | GO:0032648 | 13 | 0.824 | |
| response to tumor necrosis factor | GO:0034612 | 26 | 0.819 | |
| activation of immune response | GO:0002253 | 138 | 0.815 | |
| b cell homeostasis | GO:0001782 | 34 | 0.813 | |
| nik nf kappab signaling | GO:0038061 | 14 | 0.808 | |
| type i interferon production | GO:0032606 | 29 | 0.808 | |
| defense response to other organism | GO:0098542 | 197 | 0.807 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.790 | |
| regulation of defense response to virus | GO:0050688 | 18 | 0.781 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.763 | |
| necrotic cell death | GO:0070265 | 30 | 0.753 | |
| immune effector process | GO:0002252 | 321 | 0.747 | |
| positive regulation of interferon beta production | GO:0032728 | 8 | 0.744 | |
| type i interferon biosynthetic process | GO:0045351 | 9 | 0.743 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.742 | |
| sodium ion transport | GO:0006814 | 73 | 0.730 | |
| humoral immune response | GO:0006959 | 57 | 0.725 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.724 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.712 | |
| positive regulation of cytokine biosynthetic process | GO:0042108 | 40 | 0.706 | |
| transmembrane transport | GO:0055085 | 412 | 0.690 | |
| striated muscle contraction | GO:0006941 | 45 | 0.678 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.677 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.677 | |
| cellular response to lipid | GO:0071396 | 145 | 0.672 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.667 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 83 | 0.663 | |
| cytokine biosynthetic process | GO:0042089 | 68 | 0.661 | |
| positive regulation of defense response | GO:0031349 | 124 | 0.656 | |
| peptide biosynthetic process | GO:0043043 | 11 | 0.654 | |
| cellular response to tumor necrosis factor | GO:0071356 | 21 | 0.649 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.641 | |
| cytokine metabolic process | GO:0042107 | 71 | 0.638 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.631 | |
| cation transport | GO:0006812 | 399 | 0.627 | |
| protein catabolic process | GO:0030163 | 221 | 0.610 | |
| production of molecular mediator of immune response | GO:0002440 | 103 | 0.605 | |
| positive regulation of type i interferon production | GO:0032481 | 14 | 0.599 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.597 | |
| regulation of transporter activity | GO:0032409 | 57 | 0.590 | |
| positive regulation of ion transmembrane transporter activity | GO:0032414 | 15 | 0.587 | |
| activation of jnkk activity | GO:0007256 | 3 | 0.587 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.584 | |
| regulation of response to biotic stimulus | GO:0002831 | 38 | 0.572 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.567 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.560 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.556 | |
| regulation of cation channel activity | GO:2001257 | 22 | 0.554 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.544 | |
| cytokine production | GO:0001816 | 319 | 0.535 | |
| defense response to gram positive bacterium | GO:0050830 | 50 | 0.529 | |
| regulation of cytokine biosynthetic process | GO:0042035 | 59 | 0.528 | |
| mammary gland lobule development | GO:0061377 | 22 | 0.519 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.512 | |
| dna metabolic process | GO:0006259 | 303 | 0.508 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.503 | |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 30 | 0.501 | Human |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.500 | |
| positive regulation of immune effector process | GO:0002699 | 107 | 0.474 | |
| intracellular protein transport | GO:0006886 | 204 | 0.467 | |
| regulation of innate immune response | GO:0045088 | 91 | 0.464 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.458 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.454 | |
| protein import into nucleus | GO:0006606 | 95 | 0.450 | |
| regulation of nik nf kappab signaling | GO:1901222 | 10 | 0.445 | |
| muscle contraction | GO:0006936 | 101 | 0.439 | |
| tumor necrosis factor mediated signaling pathway | GO:0033209 | 13 | 0.429 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.425 | |
| negative regulation of b cell activation | GO:0050869 | 27 | 0.423 | |
| response to oxidative stress | GO:0006979 | 123 | 0.415 | |
| lipopolysaccharide mediated signaling pathway | GO:0031663 | 25 | 0.412 | |
| regulation of production of molecular mediator of immune response | GO:0002700 | 65 | 0.410 | |
| positive regulation of humoral immune response | GO:0002922 | 11 | 0.409 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 61 | 0.404 | |
| positive regulation of t cell cytokine production | GO:0002726 | 5 | 0.400 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.393 | |
| regulation of cytokine production involved in immune response | GO:0002718 | 26 | 0.392 | |
| glial cell apoptotic process | GO:0034349 | 3 | 0.389 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.389 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.383 | |
| adaptive immune response | GO:0002250 | 155 | 0.376 | |
| positive regulation of intracellular protein transport | GO:0090316 | 42 | 0.372 | |
| regulation of type i interferon production | GO:0032479 | 22 | 0.369 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.367 | |
| t cell activation | GO:0042110 | 289 | 0.366 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.357 | |
| negative regulation of interleukin 6 production | GO:0032715 | 17 | 0.356 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.347 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.346 | |
| protein ubiquitination | GO:0016567 | 171 | 0.344 | |
| positive regulation of response to biotic stimulus | GO:0002833 | 15 | 0.343 | |
| osteoclast differentiation | GO:0030316 | 62 | 0.336 | |
| regulation of jun kinase activity | GO:0043506 | 40 | 0.336 | |
| protein import | GO:0017038 | 101 | 0.328 | |
| lactation | GO:0007595 | 25 | 0.328 | |
| mammary gland alveolus development | GO:0060749 | 22 | 0.327 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.325 | |
| positive regulation of protein localization to nucleus | GO:1900182 | 30 | 0.324 | |
| odontogenesis of dentin containing tooth | GO:0042475 | 66 | 0.322 | |
| regulation of protein transport | GO:0051223 | 163 | 0.321 | |
| jnk cascade | GO:0007254 | 72 | 0.319 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.313 | |
| positive regulation of protein import into nucleus | GO:0042307 | 26 | 0.313 | |
| mitochondrion organization | GO:0007005 | 134 | 0.309 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.305 | |
| tyrosine phosphorylation of stat1 protein | GO:0042508 | 3 | 0.304 | |
| positive regulation of cation channel activity | GO:2001259 | 8 | 0.303 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.300 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.299 | |
| positive regulation of cytokine production involved in immune response | GO:0002720 | 19 | 0.297 | |
| positive regulation of adaptive immune response | GO:0002821 | 61 | 0.296 | |
| lymphocyte activation involved in immune response | GO:0002285 | 93 | 0.293 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.292 | |
| regulation of humoral immune response | GO:0002920 | 22 | 0.289 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.288 | |
| body fluid secretion | GO:0007589 | 53 | 0.283 | |
| odontogenesis | GO:0042476 | 78 | 0.273 | |
| positive regulation of jun kinase activity | GO:0043507 | 30 | 0.272 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.271 | |
| regulation of jnk cascade | GO:0046328 | 62 | 0.265 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.260 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.258 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.249 | |
| cellular response to nitric oxide | GO:0071732 | 4 | 0.247 | |
| immune response activating signal transduction | GO:0002757 | 116 | 0.245 | |
| muscle system process | GO:0003012 | 141 | 0.244 | |
| compound eye development | GO:0048749 | 1 | 0.244 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.243 | |
| positive regulation of sodium ion transport | GO:0010765 | 13 | 0.240 | |
| regulation of tyrosine phosphorylation of stat1 protein | GO:0042510 | 2 | 0.236 | |
| skeletal system development | GO:0001501 | 356 | 0.236 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.235 | |
| positive regulation of ion transport | GO:0043270 | 65 | 0.234 | |
| lymphocyte homeostasis | GO:0002260 | 64 | 0.227 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.226 | |
| positive regulation of intracellular transport | GO:0032388 | 70 | 0.226 | |
| neuron death | GO:0070997 | 154 | 0.225 | |
| antigen receptor mediated signaling pathway | GO:0050851 | 64 | 0.224 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.224 | |
| negative regulation of response to wounding | GO:1903035 | 77 | 0.224 | |
| antimicrobial humoral response | GO:0019730 | 11 | 0.219 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.218 | |
| leukocyte homeostasis | GO:0001776 | 79 | 0.213 | |
| jak stat cascade | GO:0007259 | 42 | 0.211 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.210 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.209 | |
| positive regulation of transmembrane transport | GO:0034764 | 29 | 0.209 | |
| regulation of cellular amide metabolic process | GO:0034248 | 10 | 0.208 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.207 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.206 | |
| positive regulation of ion transmembrane transport | GO:0034767 | 24 | 0.205 | |
| pattern recognition receptor signaling pathway | GO:0002221 | 47 | 0.203 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.203 | |
| cytokine production involved in immune response | GO:0002367 | 34 | 0.202 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.198 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.198 | |
| cytoplasmic pattern recognition receptor signaling pathway | GO:0002753 | 10 | 0.197 | |
| cell cell recognition | GO:0009988 | 44 | 0.197 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 106 | 0.197 | |
| positive regulation of neuron death | GO:1901216 | 28 | 0.195 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.195 | Human |
| leukocyte differentiation | GO:0002521 | 342 | 0.195 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.187 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.187 | |
| regulation of anion transport | GO:0044070 | 27 | 0.186 | |
| mammary gland epithelial cell proliferation | GO:0033598 | 24 | 0.186 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.186 | |
| immune response regulating signaling pathway | GO:0002764 | 125 | 0.184 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.182 | |
| interleukin 6 production | GO:0032635 | 58 | 0.182 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.178 | |
| nucleotide binding oligomerization domain containing signaling pathway | GO:0070423 | 6 | 0.178 | |
| t cell mediated immunity | GO:0002456 | 50 | 0.176 | |
| positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002824 | 61 | 0.176 | |
| positive regulation of jnk cascade | GO:0046330 | 46 | 0.174 | |
| regulation of interleukin 2 production | GO:0032663 | 28 | 0.174 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.172 | |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 80 | 0.171 | |
| response to drug | GO:0042493 | 75 | 0.168 | |
| regulation of sodium ion transport | GO:0002028 | 29 | 0.168 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.167 | |
| activation of mapkk activity | GO:0000186 | 15 | 0.167 | |
| necroptotic signaling pathway | GO:0097527 | 3 | 0.166 | |
| positive regulation of activation of membrane attack complex | GO:0001970 | 2 | 0.166 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.161 | |
| activation of mapk activity | GO:0000187 | 59 | 0.160 | |
| positive regulation of t cell mediated immunity | GO:0002711 | 24 | 0.158 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.157 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.154 | |
| single organism nuclear import | GO:1902593 | 95 | 0.151 | |
| interleukin 8 production | GO:0032637 | 4 | 0.151 | |
| regulation of lymphocyte mediated immunity | GO:0002706 | 84 | 0.150 | |
| interleukin 5 secretion | GO:0072603 | 2 | 0.149 | |
| lymph node development | GO:0048535 | 18 | 0.149 | |
| b cell activation | GO:0042113 | 161 | 0.149 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.149 | |
| positive regulation of map kinase activity | GO:0043406 | 84 | 0.149 | |
| regulation of immunoglobulin secretion | GO:0051023 | 12 | 0.148 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.147 | |
| response to acid chemical | GO:0001101 | 111 | 0.147 | |
| myeloid dendritic cell activation | GO:0001773 | 25 | 0.143 | |
| morphogenesis of an epithelial sheet | GO:0002011 | 27 | 0.141 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.140 | |
| regulation of adaptive immune response | GO:0002819 | 90 | 0.140 | |
| muscle tissue development | GO:0060537 | 308 | 0.140 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 68 | 0.137 | Human |
| protein maturation | GO:0051604 | 176 | 0.137 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.136 | |
| autophagy | GO:0006914 | 45 | 0.136 | |
| regulation of interferon gamma production | GO:0032649 | 57 | 0.133 | |
| protein homooligomerization | GO:0051260 | 43 | 0.133 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.133 | |
| immunoglobulin mediated immune response | GO:0016064 | 69 | 0.131 | |
| regulation of protein import into nucleus | GO:0042306 | 52 | 0.131 | |
| mapk cascade | GO:0000165 | 281 | 0.130 | |
| positive regulation of intrinsic apoptotic signaling pathway | GO:2001244 | 25 | 0.128 | |
| ripoptosome assembly | GO:0097343 | 6 | 0.128 | |
| extrinsic apoptotic signaling pathway via death domain receptors | GO:0008625 | 34 | 0.125 | |
| positive regulation of lymphocyte proliferation | GO:0050671 | 70 | 0.124 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.123 | |
| positive regulation of transporter activity | GO:0032411 | 17 | 0.122 | |
| regulation of jak stat cascade | GO:0046425 | 34 | 0.121 | |
| regulation of tumor necrosis factor superfamily cytokine production | GO:1903555 | 50 | 0.120 | |
| t cell cytokine production | GO:0002369 | 10 | 0.118 | |
| negative regulation of defense response | GO:0031348 | 77 | 0.117 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 81 | 0.115 | |
| signal transduction in absence of ligand | GO:0038034 | 55 | 0.115 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.112 | |
| positive regulation of interleukin 6 production | GO:0032755 | 37 | 0.110 | |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.109 | |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 87 | 0.108 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.108 | Human |
| positive regulation of secretion | GO:0051047 | 130 | 0.108 | |
| t cell activation involved in immune response | GO:0002286 | 43 | 0.108 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 65 | 0.108 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.106 | |
| angiogenesis | GO:0001525 | 201 | 0.106 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.105 | |
| regulation of organ morphogenesis | GO:2000027 | 144 | 0.104 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.103 | |
| anion transport | GO:0006820 | 177 | 0.103 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.102 | |
| positive regulation of reactive oxygen species metabolic process | GO:2000379 | 11 | 0.100 | |
| amide biosynthetic process | GO:0043604 | 16 | 0.099 | |
| digestive system development | GO:0055123 | 200 | 0.098 | |
| somatic diversification of immunoglobulins involved in immune response | GO:0002208 | 36 | 0.098 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.098 | |
| regulation of interleukin 6 production | GO:0032675 | 55 | 0.098 | |
| rhythmic process | GO:0048511 | 174 | 0.098 | |
| nuclear transport | GO:0051169 | 139 | 0.095 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.094 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.093 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.092 | |
| negative regulation of lymphocyte proliferation | GO:0050672 | 45 | 0.092 | |
| response to steroid hormone | GO:0048545 | 56 | 0.091 | |
| activation induced cell death of t cells | GO:0006924 | 10 | 0.091 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.090 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.089 | |
| regulation of interleukin 8 production | GO:0032677 | 3 | 0.089 | |
| cellular response to acid chemical | GO:0071229 | 68 | 0.087 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.086 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 39 | 0.086 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.086 | |
| regulation of interleukin 10 secretion | GO:2001179 | 4 | 0.085 | |
| regulation of t cell mediated immunity | GO:0002709 | 34 | 0.085 | |
| keratinocyte differentiation | GO:0030216 | 48 | 0.082 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.082 | |
| regulation of cell activation | GO:0050865 | 289 | 0.082 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.081 | |
| l amino acid transport | GO:0015807 | 32 | 0.081 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.080 | |
| apoptotic mitochondrial changes | GO:0008637 | 48 | 0.079 | |
| response to growth factor | GO:0070848 | 198 | 0.079 | |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 30 | 0.079 | |
| gland development | GO:0048732 | 330 | 0.079 | |
| innate immune response activating signal transduction | GO:0002758 | 50 | 0.078 | |
| regulation of cd8 positive alpha beta cytotoxic t cell extravasation | GO:2000452 | 2 | 0.077 | |
| cellular response to inorganic substance | GO:0071241 | 37 | 0.077 | |
| tumor necrosis factor production | GO:0032640 | 50 | 0.076 | |
| positive regulation of neuron apoptotic process | GO:0043525 | 25 | 0.076 | |
| immunoglobulin secretion | GO:0048305 | 17 | 0.075 | |
| regulation of protein secretion | GO:0050708 | 82 | 0.075 | |
| protein targeting | GO:0006605 | 143 | 0.074 | |
| response to amino acid | GO:0043200 | 37 | 0.073 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.072 | |
| regulation of neuron death | GO:1901214 | 134 | 0.071 | |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 151 | 0.071 | |
| response to fatty acid | GO:0070542 | 8 | 0.070 | |
| execution phase of apoptosis | GO:0097194 | 19 | 0.070 | |
| ossification | GO:0001503 | 216 | 0.069 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.068 | |
| positive regulation of interleukin 2 production | GO:0032743 | 19 | 0.068 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.068 | |
| positive regulation of protein oligomerization | GO:0032461 | 4 | 0.068 | |
| negative regulation of mapk cascade | GO:0043409 | 65 | 0.068 | |
| protein oligomerization | GO:0051259 | 67 | 0.067 | |
| nuclear import | GO:0051170 | 95 | 0.067 | |
| interleukin 6 biosynthetic process | GO:0042226 | 12 | 0.066 | |
| response to endoplasmic reticulum stress | GO:0034976 | 53 | 0.066 | |
| regulation of lymphocyte proliferation | GO:0050670 | 117 | 0.065 | |
| organic acid transport | GO:0015849 | 101 | 0.064 | |
| organelle localization | GO:0051640 | 179 | 0.064 | |
| negative regulation of protein localization to nucleus | GO:1900181 | 23 | 0.064 | |
| transcription factor import into nucleus | GO:0042991 | 26 | 0.063 | |
| positive regulation of multi organism process | GO:0043902 | 26 | 0.063 | |
| regulation of protein import into nucleus translocation | GO:0033158 | 2 | 0.062 | |
| cellular response to amino acid stimulus | GO:0071230 | 29 | 0.062 | |
| protein localization to organelle | GO:0033365 | 185 | 0.062 | |
| response to interleukin 12 | GO:0070671 | 2 | 0.061 | |
| negative regulation of map kinase activity | GO:0043407 | 34 | 0.061 | |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.061 | |
| endodermal cell fate specification | GO:0001714 | 4 | 0.061 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.060 | |
| embryonic skeletal system development | GO:0048706 | 120 | 0.059 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.058 | |
| regulation of protein processing | GO:0070613 | 96 | 0.058 | |
| cell division | GO:0051301 | 120 | 0.058 | |
| positive regulation of protein transport | GO:0051222 | 93 | 0.058 | |
| positive regulation of cellular amide metabolic process | GO:0034250 | 5 | 0.056 | |
| embryonic epithelial tube formation | GO:0001838 | 130 | 0.056 | |
| regulation of alpha beta t cell proliferation | GO:0046640 | 18 | 0.056 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.056 | |
| negative regulation of inflammatory response | GO:0050728 | 61 | 0.055 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 86 | 0.055 | |
| positive regulation of peptidase activity | GO:0010952 | 49 | 0.055 | |
| toll like receptor signaling pathway | GO:0002224 | 38 | 0.054 | |
| t cell selection | GO:0045058 | 34 | 0.054 | |
| positive regulation of protein import into nucleus translocation | GO:0033160 | 1 | 0.054 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.053 | |
| somatic recombination of immunoglobulin genes involved in immune response | GO:0002204 | 36 | 0.053 | |
| hair follicle development | GO:0001942 | 85 | 0.053 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.053 | |
| release of cytochrome c from mitochondria | GO:0001836 | 23 | 0.052 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.052 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.051 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.051 | |
| b cell mediated immunity | GO:0019724 | 71 | 0.051 | |
| cellular response to type i interferon | GO:0071357 | 10 | 0.050 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.050 | |
| detection of stimulus | GO:0051606 | 84 | 0.050 | |
| protein deacetylation | GO:0006476 | 32 | 0.050 | |
| carboxylic acid transport | GO:0046942 | 100 | 0.050 | |
| regulation of osteoblast differentiation | GO:0045667 | 67 | 0.049 | |
| activation of cysteine type endopeptidase activity | GO:0097202 | 27 | 0.049 | |
| positive regulation of reactive oxygen species biosynthetic process | GO:1903428 | 2 | 0.049 | |
| peptidyl lysine acetylation | GO:0018394 | 45 | 0.049 | |
| negative regulation of inflammatory response to antigenic stimulus | GO:0002862 | 10 | 0.049 | |
| positive regulation of lymphocyte mediated immunity | GO:0002708 | 62 | 0.049 | |
| lipid localization | GO:0010876 | 126 | 0.049 | |
| regulation of leukocyte proliferation | GO:0070663 | 121 | 0.048 | |
| positive regulation of interleukin 8 production | GO:0032757 | 2 | 0.048 | |
| bone development | GO:0060348 | 120 | 0.048 | |
| positive regulation of tyrosine phosphorylation of stat1 protein | GO:0042511 | 1 | 0.048 | |
| regulation of protein localization | GO:0032880 | 231 | 0.048 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.048 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 104 | 0.047 | |
| binding of sperm to zona pellucida | GO:0007339 | 34 | 0.047 | |
| inositol phosphate catabolic process | GO:0071545 | 4 | 0.046 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.046 | |
| positive regulation of t cell proliferation | GO:0042102 | 52 | 0.046 | |
| embryonic skeletal system morphogenesis | GO:0048704 | 91 | 0.046 | |
| positive regulation of fever generation by positive regulation of prostaglandin secretion | GO:0071812 | 2 | 0.046 | |
| protein heterooligomerization | GO:0051291 | 14 | 0.046 | |
| defense response to gram negative bacterium | GO:0050829 | 28 | 0.045 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.045 | |
| negative regulation of protein transport | GO:0051224 | 46 | 0.045 | |
| amine metabolic process | GO:0009308 | 45 | 0.045 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.045 | |
| immunoglobulin production | GO:0002377 | 73 | 0.045 | |
| nucleotide binding oligomerization domain containing 2 signaling pathway | GO:0070431 | 6 | 0.044 | |
| organic anion transport | GO:0015711 | 137 | 0.044 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 36 | 0.044 | |
| inflammatory response | GO:0006954 | 244 | 0.043 | |
| regulation of autophagy | GO:0010506 | 30 | 0.043 | |
| positive regulation of alpha beta t cell differentiation | GO:0046638 | 28 | 0.043 | |
| lymphocyte apoptotic process | GO:0070227 | 54 | 0.043 | |
| regulation of cytokine secretion involved in immune response | GO:0002739 | 4 | 0.042 | |
| amino acid transport | GO:0006865 | 61 | 0.042 | |
| cellular homeostasis | GO:0019725 | 240 | 0.042 | |
| positive regulation of leukocyte mediated immunity | GO:0002705 | 70 | 0.042 | |
| muscle cell development | GO:0055001 | 133 | 0.042 | |
| segment specification | GO:0007379 | 15 | 0.042 | |
| regulation of system process | GO:0044057 | 200 | 0.042 | |
| regulation of neuron apoptotic process | GO:0043523 | 122 | 0.042 | |
| negative regulation of nf kappab transcription factor activity | GO:0032088 | 15 | 0.042 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.041 | |
| mammary gland epithelium development | GO:0061180 | 65 | 0.041 | |
| regulation of epidermis development | GO:0045682 | 33 | 0.041 | |
| negative regulation of endopeptidase activity | GO:0010951 | 44 | 0.041 | |
| regulation of interleukin 13 secretion | GO:2000665 | 2 | 0.040 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.040 | |
| heart growth | GO:0060419 | 45 | 0.040 | |
| regulation of protein ubiquitination | GO:0031396 | 52 | 0.039 | |
| b cell apoptotic process | GO:0001783 | 19 | 0.039 | |
| protein complex localization | GO:0031503 | 19 | 0.039 | |
| positive regulation of osteoclast differentiation | GO:0045672 | 15 | 0.039 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.039 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.038 | |
| fatty acid derivative transport | GO:1901571 | 14 | 0.038 | |
| acetylcholine secretion neurotransmission | GO:0014055 | 2 | 0.038 | |
| appendage development | GO:0048736 | 166 | 0.038 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.038 | |
| t cell proliferation | GO:0042098 | 120 | 0.038 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 40 | 0.038 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 49 | 0.038 | |
| positive regulation of autophagy | GO:0010508 | 9 | 0.037 | |
| regulation of action potential | GO:0098900 | 4 | 0.037 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 57 | 0.037 | |
| positive regulation of interferon alpha production | GO:0032727 | 4 | 0.037 | |
| positive regulation of myeloid cell differentiation | GO:0045639 | 43 | 0.037 | |
| positive regulation of cell cycle process | GO:0090068 | 61 | 0.037 | |
| cellularization | GO:0007349 | 1 | 0.037 | |
| natural killer cell activation | GO:0030101 | 44 | 0.037 | |
| regulation of b cell proliferation | GO:0030888 | 39 | 0.036 | |
| positive regulation of synaptic growth at neuromuscular junction | GO:0045887 | 1 | 0.036 | |
| regulation of interleukin 6 biosynthetic process | GO:0045408 | 11 | 0.036 | |
| somite specification | GO:0001757 | 4 | 0.036 | |
| t cell homeostasis | GO:0043029 | 35 | 0.036 | |
| positive regulation of leukocyte proliferation | GO:0070665 | 73 | 0.036 | |
| acetylcholine transport | GO:0015870 | 2 | 0.036 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.036 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.036 | |
| hepatocyte apoptotic process | GO:0097284 | 11 | 0.036 | |
| segmentation | GO:0035282 | 93 | 0.035 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.035 | |
| regulation of extrinsic apoptotic signaling pathway in absence of ligand | GO:2001239 | 26 | 0.035 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.035 | |
| phagocytosis | GO:0006909 | 66 | 0.035 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.035 | |
| regulation of secretion | GO:0051046 | 274 | 0.035 | |
| circadian rhythm | GO:0007623 | 114 | 0.035 | |
| positive regulation of angiogenesis | GO:0045766 | 46 | 0.035 | |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 93 | 0.035 | |
| regulation of transcription factor import into nucleus | GO:0042990 | 24 | 0.035 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.034 | |
| digestive tract development | GO:0048565 | 190 | 0.034 | |
| response to glucocorticoid | GO:0051384 | 20 | 0.034 | |
