Mus musculus

32 known processes

Il1r1

interleukin 1 receptor, type I

(Aliases: IL-iR,Il1r-1,CD121a,MGC129154,CD121b)

Il1r1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cytokine mediated signaling pathwayGO:00192211151.000
cellular response to cytokine stimulusGO:00713451890.999
i kappab kinase nf kappab signalingGO:0007249850.998
Mouse
response to interleukin 1GO:0070555110.997
Human Rat
regulation of cell activationGO:00508652890.996
Mouse
cytokine productionGO:00018163190.996
Mouse
interleukin 18 mediated signaling pathwayGO:003565520.996
Mouse
chemokine biosynthetic processGO:004203380.992
Mouse
regulation of cytokine productionGO:00018172660.986
Mouse
positive regulation of protein secretionGO:0050714520.985
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.984
Mouse
regulation of response to woundingGO:19030341890.983
negative regulation of cytokine productionGO:0001818840.982
Mouse
cellular response to interleukin 18GO:007135130.973
Mouse
regulation of interleukin 6 productionGO:0032675550.973
Mouse
myeloid leukocyte activationGO:0002274830.972
Mouse
regulation of inflammatory responseGO:00507271470.972
positive regulation of defense responseGO:00313491240.972
Mouse
acute inflammatory responseGO:0002526410.969
Mouse
t helper cell differentiationGO:0042093280.969
Mouse
alpha beta t cell differentiation involved in immune responseGO:0002293300.968
Mouse
regulation of secretionGO:00510462740.960
Mouse
response to molecule of bacterial originGO:00022371430.959
positive regulation of inflammatory responseGO:0050729470.955
Mouse
cellular response to molecule of bacterial originGO:0071219830.954
negative regulation of chemokine productionGO:003268240.953
Mouse
cytokine metabolic processGO:0042107710.952
Mouse
regulation of acute inflammatory responseGO:0002673270.952
chemokine metabolic processGO:0050755100.951
Mouse
detection of molecule of bacterial originGO:003249020.949
regulation of cytokine biosynthetic processGO:0042035590.947
Mouse
t cell activationGO:00421102890.945
Mouse
positive regulation of cytokine productionGO:00018191740.943
Mouse
peptidyl tyrosine modificationGO:00182121450.942
response to lipopolysaccharideGO:00324961280.941
leukocyte apoptotic processGO:0071887710.939
regulation of adaptive immune responseGO:0002819900.930
Mouse
positive regulation of interleukin 6 productionGO:0032755370.927
Mouse
negative regulation of reactive oxygen species biosynthetic processGO:190342700.916
chemokine productionGO:0032602340.915
Mouse
defense response to other organismGO:00985421970.913
cellular ketone metabolic processGO:0042180840.909
regulation of peptidase activityGO:0052547960.907
inflammatory response to woundingGO:009059440.905
interleukin 6 productionGO:0032635580.897
Mouse
interleukin 2 biosynthetic processGO:0042094150.896
Mouse
positive regulation of cytokine secretionGO:0050715410.894
Mouse
peptidyl tyrosine phosphorylationGO:00181081430.890
lymphocyte activation involved in immune responseGO:0002285930.888
Mouse
response to peptide hormoneGO:00434341270.888
interleukin 2 productionGO:0032623330.886
Mouse
regulation of protein kinase activityGO:00458592320.885
cellular response to peptidoglycanGO:007122440.884
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.882
response to organonitrogen compoundGO:00102432460.874
positive regulation of protein transportGO:0051222930.871
Mouse
regulation of cytokine production involved in immune responseGO:0002718260.862
positive regulation of secretionGO:00510471300.860
Mouse
positive regulation of t cell activationGO:00508701010.857
Mouse
regulation of mapk cascadeGO:00434082480.854
regulation of establishment of protein localizationGO:00702011810.853
Mouse
positive regulation of response to woundingGO:1903036660.850
Mouse
regulation of peptide transportGO:0090087910.848
Mouse
regulation of cell migrationGO:00303342190.844
cd4 positive alpha beta t cell differentiationGO:0043367410.841
Mouse
negative regulation of immune system processGO:00026832090.840
Mouse
cellular response to lipopolysaccharideGO:0071222770.836
adaptive immune responseGO:00022501550.835
Mouse
regulation of lymphocyte differentiationGO:00456191070.829
Mouse
negative regulation of phosphorus metabolic processGO:00105631840.823
granulocyte chemotaxisGO:0071621390.821
regulation of t cell activationGO:00508631700.819
Mouse
negative regulation of cell proliferationGO:00082852960.818
regulation of chemokine productionGO:0032642300.814
Mouse
regulation of chemokine secretionGO:009019640.811
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.806
cytokine secretionGO:0050663720.804
Mouse
antibacterial peptide productionGO:000277820.797
protein processingGO:00164851630.796
response to organic cyclic compoundGO:00140701980.796
positive regulation of chemokine productionGO:0032722220.794
Mouse
protein secretionGO:00093061110.792
Mouse
regulation of lymphocyte activationGO:00512492400.792
Mouse
cellular response to lipidGO:00713961450.791
peptide transportGO:00158331330.786
Mouse
cellular response to biotic stimulusGO:0071216920.784
regulation of cellular amino acid metabolic processGO:000652150.780
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.776
regulation of protein targetingGO:1903533610.776
Mouse
mapk cascadeGO:00001652810.775
response to tumor necrosis factorGO:0034612260.775
protein localization to nucleusGO:00345041210.771
Mouse
establishment of protein localization to organelleGO:00725941180.770
Mouse
positive regulation of mapk cascadeGO:00434101700.761
regulation of endopeptidase activityGO:0052548890.761
regulation of natural killer cell differentiationGO:0032823110.759
positive regulation of cellular amine metabolic processGO:003324050.753
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.753
regulation of cellular catabolic processGO:00313292420.751
epithelial cell proliferationGO:00506731740.749
immune effector processGO:00022523210.749
Mouse
positive regulation of cell activationGO:00508671580.746
Mouse
production of molecular mediator of immune responseGO:00024401030.744
cellular amino acid metabolic processGO:00065201030.739
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.732
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.731
cellular amine metabolic processGO:0044106440.731
regulation of cellular ketone metabolic processGO:0010565660.731
positive regulation of protein modification processGO:00314012990.730
negative regulation of defense responseGO:0031348770.728
regulation of protein import into nucleusGO:0042306520.724
Mouse
positive regulation of programmed cell deathGO:00430682180.723
cell type specific apoptotic processGO:00972852680.719
regulation of hydrolase activityGO:00513362460.717
t cell differentiation involved in immune responseGO:0002292300.716
Mouse
chemotaxisGO:00069352470.714
cellular chemical homeostasisGO:00550822150.709
Rat
positive regulation of protein phosphorylationGO:00019342420.709
regulation of defense responseGO:00313472330.708
negative regulation of cellular protein metabolic processGO:00322692470.708
positive regulation by symbiont of defense related host nitric oxide productionGO:005234710.707
immune response activating signal transductionGO:00027571160.704
protein import into nucleusGO:0006606950.702
Mouse
macrophage activationGO:0042116270.700
Mouse
positive regulation of hydrolase activityGO:00513451480.699
regulation of chemokine biosynthetic processGO:004507380.696
Mouse
cholesterol metabolic processGO:0008203560.694
amine metabolic processGO:0009308450.691
cellular response to peptideGO:1901653920.682
lipopolysaccharide mediated signaling pathwayGO:0031663250.681
positive regulation of t cell proliferationGO:0042102520.679
myeloid cell apoptotic processGO:0033028220.678
protein targetingGO:00066051430.678
Mouse
regulation of insulin receptor signaling pathwayGO:0046626210.675
positive regulation of proteolysisGO:0045862850.673
positive regulation of production of molecular mediator of immune responseGO:0002702450.672
regulation of kinase activityGO:00435492490.672
transcription factor import into nucleusGO:0042991260.671
Mouse
regulation of intracellular protein transportGO:0033157820.669
Mouse
organ or tissue specific immune responseGO:0002251130.667
angiogenesisGO:00015252010.661
positive regulation of secretion by cellGO:19035321140.660
Mouse
inflammatory responseGO:00069542440.660
positive regulation of map kinase activityGO:0043406840.654
negative regulation of chemokine biosynthetic processGO:004507920.652
Mouse
regulation of secretion by cellGO:19035302490.651
Mouse
positive regulation of intracellular protein transportGO:0090316420.650
Mouse
defense response to gram positive bacteriumGO:0050830500.649
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.644
interferon beta biosynthetic processGO:004535040.636
immune response regulating signaling pathwayGO:00027641250.633
positive regulation of kinase activityGO:00336741550.627
regulation of alpha beta t cell activationGO:0046634530.624
regulation of leukocyte apoptotic processGO:2000106560.618
dna metabolic processGO:00062593030.618
cytokine biosynthetic processGO:0042089680.616
Mouse
response to defense related host nitric oxide productionGO:005256520.615
regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042430.612
lipid transportGO:0006869980.608
nuclear importGO:0051170950.605
Mouse
regulation of type 2 immune responseGO:0002828180.603
wound healing involved in inflammatory responseGO:000224640.603
induction by organism of immune response of other organism involved in symbiotic interactionGO:005255810.603
immunoglobulin mediated immune responseGO:0016064690.602
positive regulation of protein serine threonine kinase activityGO:00719021060.601
cellular response to oxidative stressGO:0034599760.601
negative regulation of interleukin 10 secretionGO:200118020.600
protein localization to organelleGO:00333651850.600
Mouse
regulation of membrane potentialGO:00423911920.596
regulation of leukocyte differentiationGO:19021051590.595
Mouse
regulation of protein localizationGO:00328802310.593
Mouse
regulation of transferase activityGO:00513382630.591
humoral immune responseGO:0006959570.588
regulation of b cell mediated immunityGO:0002712370.587
activation of cysteine type endopeptidase activityGO:0097202270.579
interleukin 5 secretionGO:007260320.578
protein maturationGO:00516041760.576
regulation of proteolysisGO:00301621640.573
cellular response to organonitrogen compoundGO:00714171450.572
regulation of lymphocyte proliferationGO:00506701170.564
negative regulation of protein metabolic processGO:00512482820.564
Mouse
cytoplasmic transportGO:00164822340.561
Mouse
response to glucocorticoidGO:0051384200.558
negative regulation of molecular functionGO:00440922580.556
leukocyte mediated immunityGO:00024431740.553
regulation of system processGO:00440572000.552
positive regulation of glial cell proliferationGO:006025240.547
tyrosine phosphorylation of stat1 proteinGO:004250830.546
type i interferon signaling pathwayGO:0060337100.544
cell adhesionGO:00071553290.544
negative regulation of phosphate metabolic processGO:00459361840.542
regulation of macrophage activationGO:0043030170.537
Mouse
regulation of protein localization to nucleusGO:1900180600.533
Mouse
growth involved in symbiotic interactionGO:0044110230.531
regulation of t cell differentiationGO:0045580830.529
Mouse
acute phase responseGO:0006953100.529
Mouse
cellular response to interferon gammaGO:0071346250.528
regulation of nucleocytoplasmic transportGO:0046822730.528
Mouse
leukocyte differentiationGO:00025213420.525
Mouse
organic acid transportGO:00158491010.524
defense response to virusGO:0051607680.523
positive regulation of leukocyte proliferationGO:0070665730.516
cellular response to hormone stimulusGO:00328701500.513
response to interleukin 15GO:007067230.512
regulation of peptidyl tyrosine phosphorylationGO:0050730930.510
activation of immune responseGO:00022531380.508
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.507
neuron deathGO:00709971540.504
regulation of nitric oxide synthase biosynthetic processGO:005176970.501
positive regulation of tyrosine phosphorylation of stat1 proteinGO:004251110.500
lymphocyte apoptotic processGO:0070227540.498
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.497
negative regulation of intracellular signal transductionGO:19025321670.497
Mouse
neutrophil migrationGO:1990266370.496
modulation by symbiont of defense related host nitric oxide productionGO:005216310.492
positive regulation of protein localization to nucleusGO:1900182300.490
Mouse
regulation of macrophage cytokine productionGO:001093580.488
erk1 and erk2 cascadeGO:0070371770.483
divalent inorganic cation homeostasisGO:00725071380.481
regulation of growth of symbiont in hostGO:0044126190.478
regulation of innate immune responseGO:0045088910.472
positive regulation of peptidase activityGO:0010952490.466
blood vessel morphogenesisGO:00485142850.466
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.463
cellular response to interleukin 4GO:0071353210.462
glial cell differentiationGO:00100011310.461
interleukin 6 mediated signaling pathwayGO:007010260.461
regulation of interleukin 2 productionGO:0032663280.451
positive regulation of transcription factor import into nucleusGO:004299380.450
Mouse
regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042830.441
reactive oxygen species biosynthetic processGO:190340980.440
cell activation involved in immune responseGO:00022631260.440
Mouse
positive t cell selectionGO:0043368230.438
fever generationGO:000166070.436
response to interleukin 4GO:0070670230.434
urogenital system developmentGO:00016552610.433
regulation of sequence specific dna binding transcription factor activityGO:00510901060.429
positive regulation of apoptotic cell clearanceGO:200042730.428
nuclear transportGO:00511691390.427
Mouse
positive regulation of apoptotic processGO:00430652170.425
positive regulation of innate immune responseGO:0045089800.423
negative regulation of phosphorylationGO:00423261660.420
tumor necrosis factor mediated signaling pathwayGO:0033209130.419
negative regulation of secretion by cellGO:1903531540.419
acylglycerol metabolic processGO:0006639550.413
negative regulation of interleukin 6 productionGO:0032715170.413
regulation of protein serine threonine kinase activityGO:00719001570.412
b cell mediated immunityGO:0019724710.412
positive regulation of lymphocyte differentiationGO:0045621610.409
Mouse
positive regulation of cell deathGO:00109422240.408
negative regulation of secretionGO:0051048610.408
regulation of neuron deathGO:19012141340.408
regulation of cellular amine metabolic processGO:0033238200.407
nitrogen compound transportGO:00717052710.407
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.399
leukocyte migrationGO:00509001240.397
regulation of inflammatory response to antigenic stimulusGO:0002861210.396
regulation of antibacterial peptide biosynthetic processGO:000280810.395
positive regulation of acute inflammatory responseGO:0002675160.395
positive regulation of antimicrobial peptide productionGO:000222510.394
negative regulation of inflammatory responseGO:0050728610.392
pattern recognition receptor signaling pathwayGO:0002221470.390
nik nf kappab signalingGO:0038061140.390
response to granulocyte macrophage colony stimulating factorGO:009701230.387
response to type i interferonGO:0034340120.385
negative regulation of erk1 and erk2 cascadeGO:0070373210.385
negative regulation of macrophage apoptotic processGO:200011030.383
modulation of growth of symbiont involved in interaction with hostGO:0044144190.381
cellular ion homeostasisGO:00068731650.380
alpha beta t cell proliferationGO:0046633210.379
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.378
response to defense related nitric oxide production by other organism involved in symbiotic interactionGO:005255120.376
negative regulation of interleukin 5 secretionGO:200066310.375
metal ion homeostasisGO:00550651890.373
protein importGO:00170381010.373
Mouse
response to corticosteroidGO:0031960200.371
t cell differentiationGO:00302171740.369
Mouse
nitric oxide synthase biosynthetic processGO:005176770.369
glycoprotein metabolic processGO:00091001160.366
positive regulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005234510.365
isotype switchingGO:0045190360.363
t cell lineage commitmentGO:0002360130.362
regulation of cytokine secretionGO:0050707610.361
Mouse
negative regulation of nik nf kappab signalingGO:190122320.359
homeostasis of number of cellsGO:00488722100.358
regulation of fatty acid metabolic processGO:0019217280.357
negative regulation of hydrolase activityGO:0051346710.356
regulation of cell motilityGO:20001452360.356
single organism nuclear importGO:1902593950.355
Mouse
allantoin metabolic processGO:000025530.354
regulation of production of molecular mediator of immune responseGO:0002700650.354
inflammatory cell apoptotic processGO:0006925110.353
interleukin 18 productionGO:003262140.351
regulation of neuron apoptotic processGO:00435231220.349
regulation of mast cell proliferationGO:007066640.346
cd4 positive alpha beta t cell lineage commitmentGO:004337360.343
t helper 1 cell differentiationGO:0045063130.342
Mouse
vascular endothelial growth factor productionGO:0010573130.342
regulation of interleukin 10 secretionGO:200117940.340
negative regulation of response to cytokine stimulusGO:006076190.338
Mouse
immunoglobulin productionGO:0002377730.335
response to interferon gammaGO:0034341340.333
t cell homeostasisGO:0043029350.332
alpha amino acid metabolic processGO:1901605590.330
regulation of vascular endothelial growth factor productionGO:0010574130.329
positive regulation of leukocyte differentiationGO:1902107860.327
Mouse
positive regulation of cell migrationGO:00303351090.326
positive regulation of macrophage activationGO:0043032100.326
Mouse
t cell extravasationGO:007268340.323
necroptotic signaling pathwayGO:009752730.321
creatinine metabolic processGO:004644930.321
regulation of map kinase activityGO:00434051200.319
positive regulation of lymphocyte proliferationGO:0050671700.319
regulation of humoral immune responseGO:0002920220.317
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005230210.317
zymogen activationGO:0031638410.316
b cell activationGO:00421131610.315
positive regulation of lymphocyte activationGO:00512511400.312
Mouse
regulation of interleukin 6 biosynthetic processGO:0045408110.310
fatty acid transportGO:0015908280.307
response to interleukin 18GO:007067340.307
Mouse
progesterone metabolic processGO:004244840.303
lymphocyte mediated immunityGO:00024491390.303
negative regulation of leukocyte apoptotic processGO:2000107310.302
cellular calcium ion homeostasisGO:00068741190.302
regulation of leukocyte proliferationGO:00706631210.300
regulation of immunoglobulin productionGO:0002637420.298
carboxylic acid transportGO:00469421000.298
alpha beta t cell activationGO:0046631910.298
Mouse
positive regulation of endopeptidase activityGO:0010950430.297
positive regulation of apoptotic signaling pathwayGO:2001235950.296
regulation of response to cytokine stimulusGO:0060759230.295
Mouse
positive regulation of cysteine type endopeptidase activityGO:2001056390.294
interleukin 11 mediated signaling pathwayGO:003815420.293
regulation of interleukin 5 secretionGO:200066220.293
t cell activation involved in immune responseGO:0002286430.292
Mouse
t cell receptor signaling pathwayGO:0050852460.289
regulation of cytokine secretion involved in immune responseGO:000273940.288
prolactin signaling pathwayGO:003816150.286
somatic recombination of immunoglobulin gene segmentsGO:0016447420.284
regulation of tyrosine phosphorylation of stat1 proteinGO:004251020.282
jak stat cascade involved in growth hormone signaling pathwayGO:006039740.282
cation homeostasisGO:00550802120.281
regulation of b cell proliferationGO:0030888390.280
positive regulation of lipid transportGO:0032370220.280
positive regulation of immune complex clearance by monocytes and macrophagesGO:009026520.280
regulation of lipid metabolic processGO:00192161180.279
fatty acid metabolic processGO:00066311210.279
organic anion transportGO:00157111370.278
organic hydroxy compound metabolic processGO:19016152030.277
regulation of cysteine type endopeptidase activityGO:2000116650.276
cellular response to interleukin 6GO:007135490.275
regulation of neutrophil chemotaxisGO:0090022140.274
somatic diversification of immune receptorsGO:0002200530.274
cellular response to granulocyte macrophage colony stimulating factor stimulusGO:009701130.273
phagocytosisGO:0006909660.272
interleukin 10 secretionGO:007260840.272
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.271
Mouse
leukocyte proliferationGO:00706611720.270
negative regulation of angiogenesisGO:0016525250.268
regulation of antimicrobial humoral responseGO:000275930.267
macrophage cytokine productionGO:001093490.267
peptidyl amino acid modificationGO:00181933360.266
regulation of protein transportGO:00512231630.266
Mouse
negative regulation of t helper 1 type immune responseGO:000282650.266
Mouse
positive regulation of epithelial cell proliferationGO:0050679680.264
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.260
cellular lipid metabolic processGO:00442553230.260
positive regulation of interleukin 2 productionGO:0032743190.258
immune complex clearance by monocytes and macrophagesGO:000243620.255
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007043010.253
connective tissue replacement involved in inflammatory response wound healingGO:000224830.253
positive regulation of nf kappab transcription factor activityGO:0051092300.252
regulation of cell adhesionGO:00301551540.251
response to oxygen levelsGO:0070482620.251
citrate metabolic processGO:000610130.249
response to steroid hormoneGO:0048545560.247
regulation of membrane protein ectodomain proteolysisGO:005104330.245
cytokine production involved in immune responseGO:0002367340.243
lymphocyte homeostasisGO:0002260640.243
myeloid leukocyte cytokine productionGO:0061082120.242
cell cell recognitionGO:0009988440.241
positive regulation of adaptive immune responseGO:0002821610.240
positive regulation of fever generationGO:003162260.240
lymphocyte proliferationGO:00466511640.238
lymphocyte migrationGO:0072676260.236
lipid homeostasisGO:0055088630.234
neutral lipid metabolic processGO:0006638570.233
response to bacterial lipoproteinGO:003249340.231
regulation of mast cell differentiationGO:006037530.230
dna recombinationGO:0006310920.229
acid secretionGO:0046717330.228
temperature homeostasisGO:0001659260.227
necroptotic processGO:0070266210.227
positive regulation of brown fat cell differentiationGO:009033640.226
negative regulation of b cell proliferationGO:0030889130.226
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.224
positive regulation of b cell mediated immunityGO:0002714260.223
negative regulation of growthGO:0045926990.222
positive regulation of organic acid transportGO:0032892110.222
negative regulation of immune effector processGO:0002698550.220
positive regulation of cytokine secretion involved in immune responseGO:000274120.220
immune response regulating cell surface receptor signaling pathwayGO:0002768800.219
toll like receptor signaling pathwayGO:0002224380.219
tissue remodelingGO:00487711020.217
negative regulation of blood vessel morphogenesisGO:2000181250.215
activation of mapk activityGO:0000187590.215
type 2 immune responseGO:0042092230.215
amide transportGO:00428861380.214
Mouse
positive regulation of gliogenesisGO:0014015270.214
gland developmentGO:00487323300.213
positive regulation of peptidyl serine phosphorylationGO:0033138250.213
digestive tract developmentGO:00485651900.213
positive regulation of activated t cell proliferationGO:004210480.212
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.211
growth of symbiont in hostGO:0044117230.209
cell chemotaxisGO:0060326810.209
regulation of natural killer cell proliferationGO:003281720.208
regulation of t cell proliferationGO:0042129920.207
t cell differentiation in thymusGO:0033077770.206
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.206
t cell proliferationGO:00420981200.205
interleukin 13 secretionGO:007261120.205
regulation of t helper 1 type immune responseGO:0002825170.203
Mouse
regulation of toll like receptor signaling pathwayGO:0034121200.202
jak stat cascadeGO:0007259420.201
epithelial tube morphogenesisGO:00605623030.201
response to dsrnaGO:0043331300.199
regulation of interleukin 18 productionGO:003266130.198
positive regulation of lipid metabolic processGO:0045834400.198
response to endoplasmic reticulum stressGO:0034976530.197
eosinophil activationGO:004330710.195
glucose homeostasisGO:00425931280.194
Rat
interleukin 4 mediated signaling pathwayGO:003577120.194
innate immune responseGO:00450871570.194
negative regulation of cell activationGO:00508661110.193
regulation of myeloid cell apoptotic processGO:0033032190.192
regulation of interleukin 8 productionGO:003267730.191
positive regulation of neuron apoptotic processGO:0043525250.190
regulation of prostaglandin endoperoxide synthase activityGO:006058420.188
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.187
lymphocyte differentiationGO:00300982420.187
Mouse
regulation of mast cell apoptotic processGO:003302550.187
defense response to bacteriumGO:00427421190.185
positive regulation of interleukin 12 productionGO:0032735210.185
regulation of ossificationGO:00302781120.184
phospholipid metabolic processGO:0006644870.182
defense response to gram negative bacteriumGO:0050829280.180
positive regulation of lipid biosynthetic processGO:0046889180.180
regulation of homeostatic processGO:00328441820.180
organonitrogen compound biosynthetic processGO:19015661920.179
positive regulation of defense response to bacteriumGO:190042610.178
regulation of interleukin 1 secretionGO:0050704150.177
small gtpase mediated signal transductionGO:0007264970.177
negative regulation of protein phosphorylationGO:00019331260.177
positive regulation of cell motilityGO:20001471160.176
anion transportGO:00068201770.176
response to peptidoglycanGO:003249490.176
granulocyte migrationGO:0097530430.176
positive regulation of nitric oxide synthase biosynthetic processGO:005177060.175
response to inorganic substanceGO:0010035960.174
Rat
lipid localizationGO:00108761260.173
regulation of alpha beta t cell proliferationGO:0046640180.172
positive regulation of cytoplasmic transportGO:1903651400.172
Mouse
positive regulation of b cell activationGO:0050871490.172
positive regulation of protein import into nucleusGO:0042307260.171
Mouse
positive regulation of behaviorGO:0048520400.169
regulation of intracellular transportGO:00323861590.168
Mouse
intrinsic apoptotic signaling pathwayGO:00971931320.168
isotype switching to ige isotypesGO:004828970.168
positive regulation of cell developmentGO:00107202370.166
regulation of erk1 and erk2 cascadeGO:0070372710.165
multicellular organismal homeostasisGO:00488711640.165
cellular response to amino acid stimulusGO:0071230290.163
regulation of protein secretionGO:0050708820.163
Mouse
reactive nitrogen species metabolic processGO:200105700.163
negative regulation of odontogenesis of dentin containing toothGO:004248910.162
peptide secretionGO:00027901140.161
isoleucine metabolic processGO:000654940.161
mammary gland lobule developmentGO:0061377220.161
positive regulation of interleukin 18 productionGO:003274120.159
response to molecule of fungal originGO:000223840.159
regulation of nucleoside metabolic processGO:00091181300.159
negative regulation of interferon gamma mediated signaling pathwayGO:006033610.159
regulation of carbohydrate metabolic processGO:0006109750.159
response to peptideGO:19016521360.158
regulation of reactive oxygen species biosynthetic processGO:190342620.158

Il1r1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.494
nervous system diseaseDOID:86300.494
retinal diseaseDOID:567900.458
retinal degenerationDOID:846600.458
sensory system diseaseDOID:005015500.458
macular degenerationDOID:444800.458
eye and adnexa diseaseDOID:149200.458
eye diseaseDOID:561400.458
disease of metabolismDOID:001466700.304
inflammatory bowel diseaseDOID:005058900.298
gastrointestinal system diseaseDOID:7700.298
intestinal diseaseDOID:529500.298