Mus musculus

307 known processes

Il2

interleukin 2

(Aliases: Il-2)

Il2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
t cell proliferationGO:00420981200.984
positive regulation of production of molecular mediator of immune responseGO:0002702450.960
regulation of mast cell activationGO:0033003210.953
adaptive immune responseGO:00022501550.952
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.950
immunoglobulin mediated immune responseGO:0016064690.946
somatic recombination of immunoglobulin gene segmentsGO:0016447420.930
leukocyte mediated immunityGO:00024431740.905
t cell differentiation in thymusGO:0033077770.905
lymphocyte differentiationGO:00300982420.887
dna metabolic processGO:00062593030.878
lymphocyte mediated immunityGO:00024491390.869
positive regulation of defense responseGO:00313491240.863
production of molecular mediator of immune responseGO:00024401030.861
regulation of leukocyte mediated immunityGO:00027031040.849
leukocyte activation involved in immune responseGO:00023661260.839
positive regulation of b cell activationGO:0050871490.837
regulation of regulated secretory pathwayGO:1903305200.828
positive regulation of regulatory t cell differentiationGO:004559140.824
positive regulation of lymphocyte mediated immunityGO:0002708620.803
regulation of cell activationGO:00508652890.791
mast cell activationGO:0045576270.787
positive regulation of t cell differentiationGO:0045582520.774
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.747
t cell differentiationGO:00302171740.739
somatic diversification of immunoglobulinsGO:0016445430.721
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.709
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.694
positive t cell selectionGO:0043368230.694
regulation of mast cell activation involved in immune responseGO:0033006170.685
positive regulation of gamma delta t cell differentiationGO:004558860.669
regulation of cd4 positive alpha beta t cell activationGO:2000514240.659
positive regulation of lymphocyte activationGO:00512511400.658
humoral immune response mediated by circulating immunoglobulinGO:0002455140.653
regulation of cytokine productionGO:00018172660.647
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.634
positive regulation of leukocyte mediated immunityGO:0002705700.631
leukocyte differentiationGO:00025213420.631
negative regulation of homeostatic processGO:0032845710.615
cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:000236140.615
leukocyte homeostasisGO:0001776790.615
t cell receptor signaling pathwayGO:0050852460.613
isotype switching to ige isotypesGO:004828970.593
positive regulation of cellular amine metabolic processGO:003324050.582
regulation of isotype switchingGO:0045191220.576
regulation of toll like receptor 2 signaling pathwayGO:003413530.575
immunoglobulin secretionGO:0048305170.575
mast cell mediated immunityGO:0002448200.566
regulation of intracellular transportGO:00323861590.562
positive regulation of t cell activationGO:00508701010.561
regulation of isotype switching to ige isotypesGO:004829370.561
positive regulation of immune effector processGO:00026991070.559
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.558
lymphocyte homeostasisGO:0002260640.553
somatic diversification of immune receptorsGO:0002200530.550
positive regulation of isotype switching to igg isotypesGO:004830470.540
somatic cell dna recombinationGO:0016444510.533
positive regulation of macrophage activationGO:0043032100.532
positive regulation of translational initiationGO:004594840.521
positive regulation of b cell mediated immunityGO:0002714260.519
regulation of alpha beta t cell differentiationGO:0046637350.511
positive regulation of cell killingGO:0031343330.511
regulation of b cell activationGO:0050864810.506
b cell proliferationGO:0042100530.504
regulation of lymphocyte differentiationGO:00456191070.496
t helper 2 cell differentiationGO:0045064120.484
immune response activating signal transductionGO:00027571160.483
regulation of b cell differentiationGO:0045577230.477
cd4 positive alpha beta t cell differentiationGO:0043367410.471
regulation of cellular amino acid metabolic processGO:000652150.464
cell fate commitmentGO:00451652100.464
immune response activating cell surface receptor signaling pathwayGO:0002429720.461
cytokine productionGO:00018163190.450
inflammatory responseGO:00069542440.446
regulation of cytokine biosynthetic processGO:0042035590.441
cellular response to molecule of bacterial originGO:0071219830.439
regulation of b cell mediated immunityGO:0002712370.439
cellular amine metabolic processGO:0044106440.437
positive regulation of isotype switchingGO:0045830150.435
chronic inflammatory response to antigenic stimulusGO:000243930.433
positive regulation of innate immune responseGO:0045089800.431
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.430
cellular response to cytokine stimulusGO:00713451890.430
myeloid leukocyte activationGO:0002274830.426
regulation of interleukin 6 productionGO:0032675550.425
t helper 1 cell lineage commitmentGO:000229620.423
positive regulation of alpha beta t cell differentiationGO:0046638280.422
positive regulation of lymphocyte proliferationGO:0050671700.410
regulation of chronic inflammatory response to antigenic stimulusGO:000287430.409
regulation of translational initiationGO:0006446150.408
regulation of mast cell proliferationGO:007066640.395
b cell activationGO:00421131610.391
positive regulation of protein phosphorylationGO:00019342420.384
positive regulation of isotype switching to ige isotypesGO:004829540.381
antigen receptor mediated signaling pathwayGO:0050851640.376
positive regulation of leukocyte differentiationGO:1902107860.370
positive regulation of immunoglobulin mediated immune responseGO:0002891260.367
antibacterial peptide productionGO:000277820.367
regulation of immunoglobulin productionGO:0002637420.363
v d j recombinationGO:0033151140.360
myeloid leukocyte differentiationGO:00025731190.352
regulation of secretion by cellGO:19035302490.349
regulation of myeloid leukocyte differentiationGO:0002761580.348
regulation of leukocyte proliferationGO:00706631210.347
regulation of immunoglobulin mediated immune responseGO:0002889370.338
inflammatory response to antigenic stimulusGO:0002437300.334
t helper cell differentiationGO:0042093280.315
peptidyl tyrosine phosphorylationGO:00181081430.315
leukocyte degranulationGO:0043299270.313
natural killer cell mediated cytotoxicityGO:0042267290.311
alpha beta t cell differentiationGO:0046632690.310
regulation of inflammatory responseGO:00507271470.301
b cell mediated immunityGO:0019724710.300
amine metabolic processGO:0009308450.298
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.293
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.293
syncytium formationGO:0006949430.291
regulation of t helper 17 cell differentiationGO:200031920.287
positive regulation of b cell proliferationGO:0030890240.284
regulation of jak stat cascadeGO:0046425340.283
activation of immune responseGO:00022531380.281
leukocyte apoptotic processGO:0071887710.279
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.271
positive regulation of protein kinase b signalingGO:0051897320.269
mast cell activation involved in immune responseGO:0002279200.267
regulation of ion transportGO:00432692150.263
negative regulation of interleukin 2 biosynthetic processGO:004508530.262
regulation of t cell differentiationGO:0045580830.261
cell activation involved in immune responseGO:00022631260.258
regulation of protein localizationGO:00328802310.257
regulation of b cell proliferationGO:0030888390.256
negative regulation of cytokine productionGO:0001818840.253
negative regulation of myeloid cell differentiationGO:0045638380.253
regulation of sequence specific dna binding transcription factor activityGO:00510901060.250
regulation of adaptive immune responseGO:0002819900.249
regulation of response to woundingGO:19030341890.244
lymphocyte proliferationGO:00466511640.240
myeloid cell activation involved in immune responseGO:0002275340.240
positive regulation of dna recombinationGO:0045911170.240
regulation of antimicrobial peptide productionGO:000278410.239
chronic inflammatory responseGO:000254490.237
regulation of inflammatory response to antigenic stimulusGO:0002861210.232
regulation of leukocyte differentiationGO:19021051590.228
alpha beta t cell activationGO:0046631910.227
negative regulation of adaptive immune responseGO:0002820250.226
eosinophil differentiationGO:003022210.222
positive regulation of cell activationGO:00508671580.222
positive regulation of stress activated mapk cascadeGO:0032874480.220
regulation of syncytium formation by plasma membrane fusionGO:0060142230.218
temperature homeostasisGO:0001659260.216
lysosome localizationGO:0032418200.212
cell type specific apoptotic processGO:00972852680.212
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.212
positive regulation of intracellular transportGO:0032388700.210
myeloid cell apoptotic processGO:0033028220.210
regulation of defense responseGO:00313472330.206
cell killingGO:0001906670.206
regulation of apoptotic signaling pathwayGO:20012331970.205
regulation of protein serine threonine kinase activityGO:00719001570.204
cellular response to lipidGO:00713961450.204
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.202
chemokine biosynthetic processGO:004203380.200
t cell homeostasisGO:0043029350.199
positive regulation of antibacterial peptide biosynthetic processGO:000696310.198
negative regulation of t helper cell differentiationGO:004562390.198
interleukin 10 secretionGO:007260840.198
regulation of tolerance induction dependent upon immune responseGO:000265210.197
carboxylic acid transportGO:00469421000.195
negative regulation of t cell activationGO:0050868650.192
regulation of peptidase activityGO:0052547960.186
regulation of cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:003282920.185
cell adhesionGO:00071553290.183
protein secretionGO:00093061110.183
protein maturationGO:00516041760.182
natural killer cell activationGO:0030101440.182
negative regulation of leukocyte differentiationGO:1902106510.181
detection of stimulusGO:0051606840.181
positive regulation of type iii hypersensitivityGO:000180530.176
peptidyl tyrosine modificationGO:00182121450.176
positive regulation of cysteine type endopeptidase activityGO:2001056390.175
gamma delta t cell activationGO:0046629130.174
negative regulation of chronic inflammatory responseGO:000267730.172
immunoglobulin productionGO:0002377730.171
regulation of endopeptidase activityGO:0052548890.170
regionalizationGO:00030023370.169
regulation of antimicrobial humoral responseGO:000275930.166
regulation of establishment of protein localizationGO:00702011810.165
cellular amino acid metabolic processGO:00065201030.165
cytokine secretionGO:0050663720.164
extrinsic apoptotic signaling pathwayGO:00971911260.163
negative regulation of interleukin 2 productionGO:003270380.161
regulation of mast cell degranulationGO:0043304160.161
interleukin 2 productionGO:0032623330.160
cytokine metabolic processGO:0042107710.159
t cell selectionGO:0045058340.159
b cell homeostasisGO:0001782340.154
regulation of t cell activationGO:00508631700.151
myeloid cell differentiationGO:00300992330.150
regulation of humoral immune responseGO:0002920220.149
negative regulation of immune effector processGO:0002698550.149
regulation of t cell proliferationGO:0042129920.148
t helper cell lineage commitmentGO:000229560.146
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.145
interleukin 6 productionGO:0032635580.145
b cell differentiationGO:0030183780.144
endodermal cell fate specificationGO:000171440.143
regulation of exocytosisGO:0017157610.143
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.143
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.142
positive regulation of myoblast differentiationGO:004566380.138
regulation of myeloid cell apoptotic processGO:0033032190.137
positive regulation of lymphocyte differentiationGO:0045621610.137
homeostasis of number of cellsGO:00488722100.136
regulation of interleukin 2 productionGO:0032663280.134
regulation of striated muscle cell differentiationGO:0051153810.134
negative regulation of mast cell apoptotic processGO:003302640.133
t cell lineage commitmentGO:0002360130.133
regulation of myeloid cell differentiationGO:0045637960.132
regulation of cytokine secretionGO:0050707610.132
regulation of dna recombinationGO:0000018340.132
lymph node developmentGO:0048535180.131
b cell activation involved in immune responseGO:0002312500.129
regulation of gamma delta t cell activationGO:004664390.128
negative regulation of myeloid dendritic cell activationGO:003088630.128
jak stat cascadeGO:0007259420.127
gonad developmentGO:00084061410.127
positive regulation of chronic inflammatory response to antigenic stimulusGO:000287620.127
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.126
positive regulation of immunoglobulin productionGO:0002639280.126
defense response to bacteriumGO:00427421190.126
regulation of secretionGO:00510462740.125
cell chemotaxisGO:0060326810.124
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.124
syncytium formation by plasma membrane fusionGO:0000768420.124
organelle localizationGO:00516401790.122
cellular response to biotic stimulusGO:0071216920.121
type 2 immune responseGO:0042092230.120
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.120
regulation of cysteine type endopeptidase activityGO:2000116650.120
b cell receptor signaling pathwayGO:0050853200.119
cytoplasmic transportGO:00164822340.119
t cell apoptotic processGO:0070231390.119
regulation of multi organism processGO:00439001110.118
cd4 positive alpha beta t cell activationGO:0035710450.117
negative regulation of multi organism processGO:0043901680.117
immune response regulating signaling pathwayGO:00027641250.116
regulation of lymphocyte mediated immunityGO:0002706840.116
regulation of hydrolase activityGO:00513362460.115
mast cell proliferationGO:007066240.115
mast cell degranulationGO:0043303190.115
negative regulation of molecular functionGO:00440922580.114
positive regulation of mhc class ii biosynthetic processGO:004534840.113
olfactory learningGO:000835520.113
positive regulation of proteolysisGO:0045862850.113
regulation of protein transportGO:00512231630.110
positive regulation of humoral immune responseGO:0002922110.109
maintenance of locationGO:0051235890.109
cytokine production involved in immune responseGO:0002367340.108
regulation of cell killingGO:0031341400.108
positive regulation of mast cell activation involved in immune responseGO:0033008100.108
cytokine mediated signaling pathwayGO:00192211150.107
negative regulation of apoptotic signaling pathwayGO:20012341040.104
t cell mediated immunityGO:0002456500.104
positive regulation of cell deathGO:00109422240.103
negative regulation of isotype switchingGO:004582940.103
striated muscle tissue developmentGO:00147062930.102
positive regulation of protein modification processGO:00314012990.101
chemotaxisGO:00069352470.101
positive regulation of map kinase activityGO:0043406840.101
positive regulation of organelle organizationGO:00106381280.101
positive regulation of adaptive immune responseGO:0002821610.100
positive regulation of cytokine secretionGO:0050715410.100
regulation of production of molecular mediator of immune responseGO:0002700650.099
positive regulation of cell developmentGO:00107202370.099
serotonin secretion involved in inflammatory responseGO:000244240.098
dephosphorylationGO:00163111290.096
gland developmentGO:00487323300.094
dna recombinationGO:0006310920.094
myeloid leukocyte mediated immunityGO:0002444420.094
response to organic cyclic compoundGO:00140701980.093
positive regulation of activation of membrane attack complexGO:000197020.093
regulation of acute inflammatory responseGO:0002673270.093
apoptotic signaling pathwayGO:00971903060.093
regulation of myotube differentiationGO:0010830620.091
positive regulation of exocytosisGO:0045921200.091
hemostasisGO:0007599780.091
regulation of alpha beta t cell activationGO:0046634530.090
cellular response to organonitrogen compoundGO:00714171450.090
nitrogen compound transportGO:00717052710.090
negative regulation of immune system processGO:00026832090.090
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.090
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.090
regulation of chronic inflammatory responseGO:000267670.089
negative regulation of t cell mediated immunityGO:000271090.088
positive regulation of alpha beta t cell activationGO:0046635390.087
positive regulation of protein kinase activityGO:00458601440.087
leukocyte proliferationGO:00706611720.087
cellular response to lipopolysaccharideGO:0071222770.086
glycoprotein metabolic processGO:00091001160.086
positive regulation of osteoclast developmentGO:200120630.086
growth involved in symbiotic interactionGO:0044110230.085
cd4 positive alpha beta t cell lineage commitmentGO:004337360.085
positive regulation of syncytium formation by plasma membrane fusionGO:0060143170.085
response to interleukin 15GO:007067230.084
response to lipopolysaccharideGO:00324961280.084
positive regulation of jun kinase activityGO:0043507300.083
regulation of leukocyte mediated cytotoxicityGO:0001910380.083
intrinsic apoptotic signaling pathwayGO:00971931320.081
regulated secretory pathwayGO:0045055320.080
cytokine biosynthetic processGO:0042089680.080
innate immune responseGO:00450871570.080
regulation of epithelial cell proliferationGO:00506781410.080
positive regulation of hydrolase activityGO:00513451480.079
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.079
positive regulation of endopeptidase activityGO:0010950430.078
detection of external stimulusGO:0009581610.077
regulation of kinase activityGO:00435492490.077
response to acid chemicalGO:00011011110.077
learned vocalization behavior or vocal learningGO:009859810.077
nuclear transportGO:00511691390.077
innate immune response activating signal transductionGO:0002758500.076
regulation of toll like receptor 4 signaling pathwayGO:003414340.076
regulation of protein kinase activityGO:00458592320.076
innate immune response in mucosaGO:000222730.075
positive regulation of peptidase activityGO:0010952490.075
sulfur compound metabolic processGO:00067901000.075
humoral immune responseGO:0006959570.075
natural killer cell proliferationGO:000178730.074
positive regulation of chronic inflammatory responseGO:000267840.074
i kappab kinase nf kappab signalingGO:0007249850.074
neuron deathGO:00709971540.074
negative regulation of myeloid leukocyte differentiationGO:0002762200.073
negative regulation of t cell mediated cytotoxicityGO:000191530.073
regulation of proteolysisGO:00301621640.072
cell cell recognitionGO:0009988440.071
negative regulation of protein metabolic processGO:00512482820.071
necroptotic signaling pathwayGO:009752730.070
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.070
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.070
progesterone metabolic processGO:004244840.069
regulation of vasculature developmentGO:1901342880.069
tyrosine phosphorylation of stat5 proteinGO:004250690.069
regulation of innate immune responseGO:0045088910.068
alpha beta t cell lineage commitmentGO:000236370.068
single organism cell adhesionGO:00986021560.068
negative regulation of phosphate metabolic processGO:00459361840.067
regulation of myeloid leukocyte mediated immunityGO:0002886250.067
translational initiationGO:0006413240.067
antimicrobial peptide productionGO:000277520.067
positive regulation of programmed cell deathGO:00430682180.067
regulation of peptidyl tyrosine phosphorylationGO:0050730930.067
antibacterial peptide biosynthetic processGO:000278020.066
cellular response to interleukin 15GO:007135020.066
t cell differentiation involved in immune responseGO:0002292300.066
negative regulation of cytokine production involved in immune responseGO:000271950.066
negative regulation of toll like receptor 2 signaling pathwayGO:003413630.066
protein processingGO:00164851630.064
activation of cysteine type endopeptidase activityGO:0097202270.064
platelet activationGO:0030168400.064
lipid localizationGO:00108761260.063
endoderm developmentGO:0007492450.063
skeletal muscle organ developmentGO:00605381630.062
cellular calcium ion homeostasisGO:00068741190.062
learningGO:0007612980.062
positive regulation of cytokine productionGO:00018191740.062
cellular chemical homeostasisGO:00550822150.062
regulation of transferase activityGO:00513382630.062
detection of abiotic stimulusGO:0009582600.061
cellular ketone metabolic processGO:0042180840.061
regulation of jun kinase activityGO:0043506400.061
divalent inorganic cation transportGO:00725111780.061
osteoclast differentiationGO:0030316620.060
regulation of lymphocyte activationGO:00512492400.060
lymphocyte activation involved in immune responseGO:0002285930.059
mast cell apoptotic processGO:003302450.059
negative regulation of myeloid cell apoptotic processGO:0033033110.059
defense response to gram negative bacteriumGO:0050829280.058
regulation of bindingGO:00510981110.058
reactive oxygen species metabolic processGO:0072593840.058
isotype switching to igg isotypesGO:0048291100.058
regulation of cellular amine metabolic processGO:0033238200.058
positive regulation of apoptotic processGO:00430652170.058
zymogen activationGO:0031638410.057
multicellular organismal homeostasisGO:00488711640.057
positive regulation of transferase activityGO:00513471670.057
negative regulation of interleukin 5 productionGO:003271440.057
myotube differentiationGO:00149021050.057
positive regulation of activated t cell proliferationGO:004210480.057
leukocyte mediated cytotoxicityGO:0001909620.056
positive regulation of mast cell activationGO:0033005120.055
muscle cell proliferationGO:0033002520.055
regulation of cellular ketone metabolic processGO:0010565660.054
regulation of activated t cell proliferationGO:0046006160.054
t cell activation involved in immune responseGO:0002286430.054
calcium ion transportGO:00068161590.053
positive regulation of protein transportGO:0051222930.053
regulation of leukocyte degranulationGO:0043300200.052
regulation of map kinase activityGO:00434051200.052
isotype switchingGO:0045190360.052
cell divisionGO:00513011200.052
immune effector processGO:00022523210.052
antimicrobial peptide biosynthetic processGO:000277720.052
negative regulation of nervous system developmentGO:00519611560.051
sensory perceptionGO:00076002450.051
tolerance induction dependent upon immune responseGO:000246110.051
protein modification by small protein conjugationGO:00324461870.051
positive regulation of cytokine biosynthetic processGO:0042108400.050
cellular zinc ion homeostasisGO:000688290.050
divalent metal ion transportGO:00708381720.050
metal ion homeostasisGO:00550651890.050
regulation of neuron deathGO:19012141340.050
alpha beta t cell differentiation involved in immune responseGO:0002293300.050
response to molecule of bacterial originGO:00022371430.049
mast cell homeostasisGO:003302350.049
positive regulation of myeloid leukocyte mediated immunityGO:0002888140.049
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.049
carbohydrate metabolic processGO:00059752300.049
lymphocyte costimulationGO:0031294150.049
immune response inhibiting signal transductionGO:000276540.049
sequestering of metal ionGO:0051238190.048
response to testosteroneGO:003357430.048
t helper 2 cell cytokine productionGO:003574540.048
regulation of protein kinase b signalingGO:0051896560.047
t cell activationGO:00421102890.047
positive regulation of reactive oxygen species biosynthetic processGO:190342820.047
regulation of mast cell differentiationGO:006037530.046
striated muscle cell developmentGO:00550021250.046
cellular ion homeostasisGO:00068731650.046
fever generationGO:000166070.046
positive regulation of myotube differentiationGO:0010831240.045
gamma delta t cell differentiationGO:0042492110.045
sensory organ morphogenesisGO:00905962420.045
hormone secretionGO:00468791280.045
circadian rhythmGO:00076231140.045
regulation of reactive oxygen species metabolic processGO:2000377400.045
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.044
positive regulation of myeloid cell differentiationGO:0045639430.043
skeletal muscle fiber developmentGO:0048741580.043
detection of mechanical stimulus involved in sensory perceptionGO:0050974230.043
response to protozoanGO:0001562280.043
negative regulation of muscle cell differentiationGO:0051148330.043
detection of mechanical stimulusGO:0050982270.042
positive regulation of defense response to bacteriumGO:190042610.042
regulation of humoral immune response mediated by circulating immunoglobulinGO:0002923100.042
muscle cell differentiationGO:00426922610.041
regulation of body fluid levelsGO:00508781620.041
positive regulation of kinase activityGO:00336741550.041
actin cytoskeleton organizationGO:00300362200.041
pre b cell differentiationGO:000232970.041
epidermis developmentGO:00085441870.041
erk1 and erk2 cascadeGO:0070371770.041
immune response regulating cell surface receptor signaling pathwayGO:0002768800.040
cellular lipid metabolic processGO:00442553230.040
defense response to gram positive bacteriumGO:0050830500.040
positive regulation of jak stat cascadeGO:0046427220.040
cellular response to transforming growth factor beta stimulusGO:0071560880.040
activation of innate immune responseGO:0002218560.039
negative regulation of leukocyte proliferationGO:0070664460.039
positive regulation of t cell proliferationGO:0042102520.039
mature dendritic cell differentiationGO:009702930.039
negative regulation of cytokine secretionGO:0050710150.038
regulation of natural killer cell mediated immunityGO:0002715190.038
protein localization to nucleusGO:00345041210.038
wnt signaling pathwayGO:00160551880.038
positive regulation of jnk cascadeGO:0046330460.038
exocytosisGO:00068871210.038
myoblast differentiationGO:0045445520.038
organelle assemblyGO:00709251770.038
organic hydroxy compound metabolic processGO:19016152030.038
negative regulation of interferon gamma productionGO:0032689180.038
tumor necrosis factor mediated signaling pathwayGO:0033209130.038
anatomical structure homeostasisGO:00602491450.038
intracellular protein transportGO:00068862040.038
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.037
response to organonitrogen compoundGO:00102432460.037
muscle cell developmentGO:00550011330.037
regulation of cellular component biogenesisGO:00440871810.037
pattern recognition receptor signaling pathwayGO:0002221470.037
defense response to other organismGO:00985421970.037
interleukin 2 mediated signaling pathwayGO:003811020.037
muscle tissue developmentGO:00605373080.037
cellular homeostasisGO:00197252400.037
cholesterol metabolic processGO:0008203560.037
positive regulation of protein localization to nucleusGO:1900182300.037
mammary gland lobule developmentGO:0061377220.037
neuromuscular synaptic transmissionGO:0007274160.036
positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292560.036
mammary gland epithelial cell proliferationGO:0033598240.035

Il2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.090
immune system diseaseDOID:291400.090
disease of cellular proliferationDOID:1456600.064
cancerDOID:16200.064
organ system cancerDOID:005068600.041
nervous system diseaseDOID:86300.040
carbohydrate metabolism diseaseDOID:005001300.037
glucose metabolism diseaseDOID:419400.037
disease of metabolismDOID:001466700.037
diabetes mellitusDOID:935100.037
acquired metabolic diseaseDOID:006015800.037