Mus musculus

88 known processes

Il6st

interleukin 6 signal transducer

(Aliases: CD130,D13Ertd699e,gp130,BB405851,5133400A03Rik,AA389424)

Il6st biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.995
Human
amine metabolic processGO:0009308450.995
regulation of peptidyl tyrosine phosphorylationGO:0050730930.992
Human
activation of mapk activity involved in innate immune responseGO:003541920.992
regulation of cellular ketone metabolic processGO:0010565660.989
cellular ketone metabolic processGO:0042180840.980
peptidyl tyrosine phosphorylationGO:00181081430.980
Human Mouse
peptidyl amino acid modificationGO:00181933360.973
Human Mouse
positive regulation of adaptive immune responseGO:0002821610.970
Mouse
peptidyl tyrosine modificationGO:00182121450.968
Human Mouse
tyrosine phosphorylation of stat3 proteinGO:0042503120.967
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.966
positive regulation of cellular amino acid metabolic processGO:004576430.948
myeloid cell apoptotic processGO:0033028220.944
positive regulation of kinase activityGO:00336741550.940
leukocyte homeostasisGO:0001776790.931
regulation of cell activationGO:00508652890.913
Human Mouse
activation of janus kinase activityGO:004297620.910
regulation of mast cell apoptotic processGO:003302550.904
cellular response to interleukin 6GO:007135490.901
Human Rat
response to interleukin 15GO:007067230.889
regulation of mapk cascadeGO:00434082480.888
lactationGO:0007595250.881
positive regulation of cell developmentGO:00107202370.880
regulation of tyrosine phosphorylation of stat proteinGO:0042509200.878
Human
cellular amine metabolic processGO:0044106440.878
regulation of tyrosine phosphorylation of stat1 proteinGO:004251020.861
Human
regulation of tyrosine phosphorylation of stat3 proteinGO:0042516100.859
Human
t helper 1 cell differentiationGO:0045063130.853
gland developmentGO:00487323300.853
morphogenesis of a branching structureGO:00017632030.850
response to host defensesGO:005220030.847
leukocyte differentiationGO:00025213420.837
regulation of t cell activationGO:00508631700.829
Human
regulation of cellular amine metabolic processGO:0033238200.826
ion transmembrane transportGO:00342203610.825
myeloid cell homeostasisGO:00022621140.825
organ regenerationGO:003110020.823
jak stat cascade involved in growth hormone signaling pathwayGO:006039740.811
negative regulation of t cell activationGO:0050868650.807
regulation of leukocyte apoptotic processGO:2000106560.806
positive regulation of glial cell proliferationGO:006025240.801
angiogenesisGO:00015252010.800
positive regulation of t cell differentiationGO:0045582520.792
cellular amino acid metabolic processGO:00065201030.790
negative regulation of protein metabolic processGO:00512482820.784
regulation of chemotaxisGO:0050920530.782
cellular amide metabolic processGO:0043603580.781
regulation of adaptive immune responseGO:0002819900.780
Mouse
organonitrogen compound biosynthetic processGO:19015661920.778
regulation of cell adhesionGO:00301551540.777
positive regulation of protein modification processGO:00314012990.775
Human
adaptive immune responseGO:00022501550.769
Mouse
regulation of cellular response to stressGO:00801351590.766
Zebrafish
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729620.765
mapk cascadeGO:00001652810.760
tyrosine phosphorylation of stat1 proteinGO:004250830.757
Human
positive regulation of cytokine productionGO:00018191740.756
Mouse
positive regulation of mapk cascadeGO:00434101700.747
regulation of cell motilityGO:20001452360.742
Rat
mast cell apoptotic processGO:003302450.739
regulation of protein kinase activityGO:00458592320.731
regulation of cellular amino acid metabolic processGO:000652150.731
homeostasis of number of cellsGO:00488722100.729
regulation of cd4 positive alpha beta t cell activationGO:2000514240.728
negative regulation of leukocyte differentiationGO:1902106510.727
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.726
Mouse
regulation of alpha beta t cell differentiationGO:0046637350.725
retina morphogenesis in camera type eyeGO:0060042450.717
regulation of leukocyte differentiationGO:19021051590.717
establishment of protein localization to organelleGO:00725941180.715
regulation of peptidase activityGO:0052547960.709
natural killer cell proliferationGO:000178730.708
regulation of t cell differentiationGO:0045580830.707
cellular response to peptideGO:1901653920.705
positive t cell selectionGO:0043368230.705
mast cell proliferationGO:007066240.704
radial glia guided migration of purkinje cellGO:002194260.703
negative regulation of t helper 1 cell differentiationGO:004562630.702
regulation of canonical wnt signaling pathwayGO:0060828820.697
response to lipopolysaccharideGO:00324961280.696
Mouse
lipid homeostasisGO:0055088630.694
dna metabolic processGO:00062593030.690
Mouse
regulation of inflammatory responseGO:00507271470.690
cellular response to amino acid stimulusGO:0071230290.679
positive regulation of interleukin 2 biosynthetic processGO:004508680.679
regulation of cell migrationGO:00303342190.674
Rat
regulation of type 2 immune responseGO:0002828180.674
Mouse
nuclear transportGO:00511691390.671
ameboidal type cell migrationGO:00016671280.665
regenerationGO:0031099380.661
Zebrafish
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.659
regulation of protein import into nucleusGO:0042306520.657
negative regulation of lymphocyte differentiationGO:0045620320.651
regulation of smad protein import into nucleusGO:006039030.651
amide transportGO:00428861380.650
lymphocyte homeostasisGO:0002260640.649
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.640
Mouse
interleukin 6 mediated signaling pathwayGO:007010260.637
Human Rat
peptidyl serine phosphorylationGO:0018105740.632
cell adhesionGO:00071553290.629
regulation of mast cell proliferationGO:007066640.620
regulation of lymphocyte activationGO:00512492400.616
Human Mouse
response to interleukin 6GO:0070741100.609
Human Rat
protein localization to nucleusGO:00345041210.608
positive regulation of cell deathGO:00109422240.608
regulation of sequence specific dna binding transcription factor activityGO:00510901060.608
isotype switching to ige isotypesGO:004828970.601
positive regulation of leukocyte differentiationGO:1902107860.601
skeletal system morphogenesisGO:00487052030.597
type i interferon signaling pathwayGO:0060337100.596
positive regulation of map kinase activityGO:0043406840.588
cd4 positive alpha beta t cell differentiationGO:0043367410.588
cellular response to organonitrogen compoundGO:00714171450.587
macrophage fusionGO:003423830.586
nucleocytoplasmic transportGO:00069131390.578
citrate metabolic processGO:000610130.574
t helper cell differentiationGO:0042093280.571
cellular response to biotic stimulusGO:0071216920.568
positive regulation of cellular amine metabolic processGO:003324050.568
lateral line system developmentGO:004892510.564
regulation of myeloid cell differentiationGO:0045637960.563
t cell differentiationGO:00302171740.563
negative regulation of alpha beta t cell activationGO:0046636180.562
response to oxygen levelsGO:0070482620.562
regulation of activation of jak2 kinase activityGO:001053410.560
epidermis developmentGO:00085441870.554
cellular response to growth factor stimulusGO:00713631970.546
somatic recombination of immunoglobulin gene segmentsGO:0016447420.545
Mouse
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.544
cd4 positive alpha beta t cell lineage commitmentGO:004337360.543
progesterone metabolic processGO:004244840.540
activation of mapk activityGO:0000187590.539
positive regulation of apoptotic signaling pathwayGO:2001235950.534
positive regulation of tyrosine phosphorylation of stat3 proteinGO:004251770.532
Human
t cell differentiation in thymusGO:0033077770.531
muscle tissue developmentGO:00605373080.527
lymphocyte differentiationGO:00300982420.526
nuclear importGO:0051170950.520
response to amino acidGO:0043200370.517
ribose phosphate biosynthetic processGO:0046390590.515
cytokine productionGO:00018163190.514
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126930.514
response to radiationGO:00093141650.514
somatic diversification of immunoglobulinsGO:0016445430.514
Mouse
positive regulation of mast cell proliferationGO:007066830.510
t helper 1 type immune responseGO:0042088250.509
Mouse
regulation of system processGO:00440572000.507
response to organic cyclic compoundGO:00140701980.505
response to corticosteroidGO:0031960200.505
positive regulation of cell proliferation involved in heart valve morphogenesisGO:000325110.493
regulation of interleukin 8 productionGO:003267730.493
positive regulation of epidermal growth factor activated receptor activityGO:004574120.489
bone morphogenesisGO:0060349780.489
t helper 1 cell lineage commitmentGO:000229620.486
regulation of lymphocyte differentiationGO:00456191070.480
chemokine productionGO:0032602340.480
negative regulation of lymphocyte apoptotic processGO:0070229240.478
regulation of protein targetingGO:1903533610.466
morphogenesis of a branching epitheliumGO:00611381930.463
regulation of cytokine productionGO:00018172660.462
Mouse
response to decreased oxygen levelsGO:0036293590.460
regulation of insulin receptor signaling pathwayGO:0046626210.459
regulation of protein serine threonine kinase activityGO:00719001570.453
reactive oxygen species metabolic processGO:0072593840.451
response to molecule of bacterial originGO:00022371430.449
Mouse
negative regulation of t cell differentiationGO:0045581230.445
cellular response to hormone stimulusGO:00328701500.445
negative regulation of type 2 immune responseGO:000282980.443
Mouse
mucopolysaccharide metabolic processGO:1903510250.442
regulation of natural killer cell differentiationGO:0032823110.440
epidermal growth factor receptor signaling pathwayGO:0007173280.440
positive regulation of alpha beta t cell differentiationGO:0046638280.434
response to granulocyte macrophage colony stimulating factorGO:009701230.434
nitrogen compound transportGO:00717052710.431
positive regulation of apoptotic processGO:00430652170.430
b cell activationGO:00421131610.427
Mouse
negative regulation of tyrosine phosphorylation of stat proteinGO:004253230.424
hindbrain radial glia guided cell migrationGO:0021932120.422
peptidyl serine modificationGO:0018209830.421
glucose homeostasisGO:00425931280.418
epithelial cell proliferationGO:00506731740.415
macromolecule catabolic processGO:00090572810.413
negative regulation of growthGO:0045926990.413
embryonic placenta developmentGO:0001892980.411
stem cell differentiationGO:00488632680.408
ovulation cycleGO:0042698590.408
t helper cell lineage commitmentGO:000229560.400
regulation of map kinase activityGO:00434051200.399
negative regulation of cellular response to growth factor stimulusGO:0090288460.399
luteinizationGO:000155380.398
positive regulation of membrane protein ectodomain proteolysisGO:005104430.398
regulation of notch signaling pathwayGO:0008593350.397
defense response to other organismGO:00985421970.396
Mouse
phagocytosisGO:0006909660.394
mechanoreceptor differentiationGO:0042490670.394
regulation of isotype switching to ige isotypesGO:004829370.391
negative regulation of immune system processGO:00026832090.388
Mouse
cell chemotaxisGO:0060326810.386
Mouse
regulation of kinase activityGO:00435492490.381
modulation by virus of host morphology or physiologyGO:001904830.381
regulation of neuron projection regenerationGO:007057070.374
Zebrafish
positive regulation of reactive oxygen species metabolic processGO:2000379110.373
alcohol metabolic processGO:00060661160.373
negative regulation of t helper 2 cell differentiationGO:004562940.373
regulation of cysteine type endopeptidase activityGO:2000116650.372
fibronectin dependent thymocyte migrationGO:007268110.371
t cell lineage commitmentGO:0002360130.370
regulation of activation of janus kinase activityGO:001053310.368
erythrocyte differentiationGO:0030218880.367
lymphocyte activation involved in immune responseGO:0002285930.367
Mouse
wnt signaling pathwayGO:00160551880.367
t cell apoptotic processGO:0070231390.365
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126740.364
inflammatory responseGO:00069542440.363
cd4 positive alpha beta t cell activationGO:0035710450.362
connective tissue developmentGO:00614481790.360
t cell activationGO:00421102890.355
Human
positive regulation of protein serine threonine kinase activityGO:00719021060.355
extrinsic apoptotic signaling pathwayGO:00971911260.354
leukocyte activation involved in immune responseGO:00023661260.352
Mouse
extracellular matrix organizationGO:00301981470.351
regulation of body fluid levelsGO:00508781620.351
positive regulation of cyclin dependent protein serine threonine kinase activityGO:004573760.349
cellular response to cytokine stimulusGO:00713451890.348
regulation of myeloid leukocyte differentiationGO:0002761580.347
negative regulation of cell developmentGO:00107211690.346
positive regulation of chemotaxisGO:0050921380.339
regulation of natural killer cell proliferationGO:003281720.337
wound healingGO:00420601570.335
protein importGO:00170381010.334
regulation of defense responseGO:00313472330.333
cell activation involved in immune responseGO:00022631260.333
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.332
regulation of t helper cell differentiationGO:0045622140.331
regulation of protein secretionGO:0050708820.329
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.329
cellular lipid metabolic processGO:00442553230.329
Rat
multicellular organism growthGO:00352641610.328
prolactin signaling pathwayGO:003816150.325
negative regulation of tyrosine phosphorylation of stat3 proteinGO:004251810.325
positive regulation of isotype switching to ige isotypesGO:004829540.324
regulation of peptidyl serine phosphorylationGO:0033135390.323
positive regulation of reactive oxygen species biosynthetic processGO:190342820.319
negative regulation of blood vessel endothelial cell migrationGO:004353730.319
regulation of actin cytoskeleton organizationGO:0032956840.318
creatinine metabolic processGO:004644930.317
cellular response to growth hormone stimulusGO:007137870.316
negative regulation of phosphorylationGO:00423261660.315
regulation of b cell differentiationGO:0045577230.315
posttranscriptional regulation of gene expressionGO:00106081550.314
negative regulation of phosphorus metabolic processGO:00105631840.314
cell growth involved in cardiac muscle cell developmentGO:006104930.311
detection of chemical stimulus involved in sensory perception of tasteGO:005091230.310
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.310
Mouse
immunoglobulin mediated immune responseGO:0016064690.310
Mouse
response to glucocorticoidGO:0051384200.309
t cell activation involved in immune responseGO:0002286430.309
positive regulation of t cell activationGO:00508701010.309
Human
positive regulation of defense responseGO:00313491240.307
interleukin 4 mediated signaling pathwayGO:003577120.304
female sex differentiationGO:0046660840.301
regulation of chemokine productionGO:0032642300.294
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.293
cellular response to granulocyte macrophage colony stimulating factor stimulusGO:009701130.293
negative regulation of interferon gamma mediated signaling pathwayGO:006033610.292
positive regulation of programmed cell deathGO:00430682180.290
regulation of hormone levelsGO:00108172110.290
regulation of production of molecular mediator of immune responseGO:0002700650.289
Mouse
negative regulation of alpha beta t cell differentiationGO:0046639120.288
stem cell developmentGO:00488642190.287
signal transduction in absence of ligandGO:0038034550.286
regulation of endopeptidase activityGO:0052548890.286
isoleucine metabolic processGO:000654940.286
positive regulation of protein kinase activityGO:00458601440.285
negative regulation of immune effector processGO:0002698550.283
positive regulation of lymphocyte differentiationGO:0045621610.281
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720540.275
prostate gland morphogenesisGO:0060512320.272
bone developmentGO:00603481200.271
negative regulation of cell proliferationGO:00082852960.271
positive regulation of endopeptidase activityGO:0010950430.271
cartilage developmentGO:00512161400.269
isotype switchingGO:0045190360.269
Mouse
cellular response to peptide hormone stimulusGO:0071375920.268
replacement ossificationGO:0036075260.265
positive regulation of activated t cell proliferationGO:004210480.265
regulation of heart contractionGO:0008016770.264
ribonucleotide biosynthetic processGO:0009260590.262
regulation of neuron differentiationGO:00456642810.262
Zebrafish
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.262
regulation of establishment of protein localizationGO:00702011810.261
engulfment of apoptotic cellGO:004365230.261
organ or tissue specific immune responseGO:0002251130.259
leukocyte migrationGO:00509001240.259
Mouse
positive regulation of nervous system developmentGO:00519622210.259
digestive tract developmentGO:00485651900.257
mast cell homeostasisGO:003302350.257
carbohydrate homeostasisGO:00335001280.257
negative regulation of lymphocyte activationGO:0051250910.255
regulation of transcription factor import into nucleusGO:0042990240.254
negative regulation of intracellular transportGO:0032387380.253
cell fate commitmentGO:00451652100.252
regulation of protein localizationGO:00328802310.251
regulation of alpha beta t cell activationGO:0046634530.251
positive regulation of b cell differentiationGO:0045579130.250
type 2 immune responseGO:0042092230.250
Mouse
protein targetingGO:00066051430.249
regulation of cell morphogenesis involved in differentiationGO:00107691510.248
regulation of t helper 1 cell differentiationGO:004562570.248
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.247
t helper 2 cell differentiationGO:0045064120.245
alpha beta t cell differentiation involved in immune responseGO:0002293300.245
negative regulation of leukocyte apoptotic processGO:2000107310.245
positive regulation of gamma delta t cell differentiationGO:004558860.244
regulation of lymphocyte apoptotic processGO:0070228410.244
positive regulation of inflammatory responseGO:0050729470.242
salivary gland developmentGO:0007431370.240
positive regulation of jak stat cascadeGO:0046427220.240
Human
ripoptosome assembly involved in necroptotic processGO:190102660.239
regulation of myeloid cell apoptotic processGO:0033032190.239
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.239
aminoglycan metabolic processGO:0006022340.238
transforming growth factor beta receptor signaling pathwayGO:0007179710.236
chemotaxisGO:00069352470.235
Mouse
positive regulation of protein phosphorylationGO:00019342420.233
Human
negative regulation of cellular component organizationGO:00511291940.233
valine metabolic processGO:000657340.233
positive regulation of natural killer cell proliferationGO:003281920.233
protein import into nucleusGO:0006606950.232
necroptotic processGO:0070266210.230
collagen biosynthetic processGO:003296470.230
body fluid secretionGO:0007589530.230
t cell selectionGO:0045058340.230
negative regulation of inflammatory responseGO:0050728610.229
positive regulation of b cell mediated immunityGO:0002714260.229
collagen metabolic processGO:0032963170.227
mesenchyme developmentGO:00604851520.226
urogenital system developmentGO:00016552610.226
negative regulation of epithelial cell proliferationGO:0050680640.223
positive regulation of peptidase activityGO:0010952490.223
dna recombinationGO:0006310920.222
Mouse
intracellular protein transportGO:00068862040.222
alpha beta t cell activationGO:0046631910.222
antibacterial peptide productionGO:000277820.220
positive regulation of notch signaling pathwayGO:0045747180.219
regulation of cytoskeleton organizationGO:00514931220.219
taurine metabolic processGO:001953040.219
immunoglobulin productionGO:0002377730.218
Mouse
tyrosine phosphorylation of stat proteinGO:0007260230.218
Human
muscle system processGO:00030121410.217
digestive system developmentGO:00551232000.216
keratinocyte migrationGO:005154630.215
negative regulation of interleukin 8 productionGO:003271710.215
extracellular structure organizationGO:00430621480.214
salivary gland morphogenesisGO:0007435330.214
positive regulation of leukocyte proliferationGO:0070665730.214
Human
cytokine mediated signaling pathwayGO:00192211150.213
leukocyte apoptotic processGO:0071887710.212
biomineral tissue developmentGO:0031214640.211
positive regulation of tyrosine phosphorylation of stat1 proteinGO:004251110.210
Human
allantoin metabolic processGO:000025530.210
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.210
neutrophil apoptotic processGO:000178130.209
regulation of jak stat cascadeGO:0046425340.209
Human
transmembrane transportGO:00550854120.207
regulation of cell projection organizationGO:00313442060.207
Zebrafish
transcription factor import into nucleusGO:0042991260.206
muscle cell proliferationGO:0033002520.206
respiratory tube developmentGO:00303231670.203
cellular response to x rayGO:007148120.203
negative regulation of homeostatic processGO:0032845710.202
development of secondary male sexual characteristicsGO:004654430.201
cellular lactam metabolic processGO:007233830.201
prostate gland developmentGO:0030850480.201
regulation of organelle organizationGO:00330432890.199
single organism nuclear importGO:1902593950.199
alpha beta t cell differentiationGO:0046632690.199
sphingolipid metabolic processGO:0006665450.198
regulation of b cell mediated immunityGO:0002712370.195
Mouse
positive regulation of phosphatidylinositol 3 kinase signalingGO:0014068200.194
phospholipid metabolic processGO:0006644870.194
skeletal system developmentGO:00015013560.194
cell divisionGO:00513011200.193
b cell differentiationGO:0030183780.192
response to ionizing radiationGO:0010212420.191
regulation of t helper 2 cell differentiationGO:004562880.190
regulation of tight junction assemblyGO:200081020.190
response to growth factorGO:00708481980.189
protein maturationGO:00516041760.188
positive regulation of cell adhesionGO:0045785800.188
innate immune response in mucosaGO:000222730.188
regulation of wnt signaling pathwayGO:00301111230.187
response to organonitrogen compoundGO:00102432460.187
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.187
regulation of t cell anergyGO:000266740.187
positive regulation of peptidyl serine phosphorylationGO:0033138250.184
peptide transportGO:00158331330.184
response to defenses of other organism involved in symbiotic interactionGO:005217330.184
negative regulation of glycolytic processGO:004582040.183
regulation of leukocyte mediated immunityGO:00027031040.183
Mouse
negative regulation of protein modification processGO:00314001630.182
positive regulation of nucleotide biosynthetic processGO:0030810260.182
response to peptide hormoneGO:00434341270.182
purine ribonucleotide biosynthetic processGO:0009152590.180
mesenchymal cell differentiationGO:00487621070.180
single organism cell adhesionGO:00986021560.180
regulation of t cell apoptotic processGO:0070232280.179
negative regulation of cellular amino acid metabolic processGO:004576300.179
regulation of organ morphogenesisGO:20000271440.178
placenta developmentGO:00018901400.178
creatine metabolic processGO:000660040.177
regulation of cellular component biogenesisGO:00440871810.177
appendage developmentGO:00487361660.177
aminoglycan catabolic processGO:000602630.176
skin developmentGO:00435882200.175
response to interferon gammaGO:0034341340.174
positive regulation of lipid metabolic processGO:0045834400.174
negative regulation of reactive oxygen species biosynthetic processGO:190342700.173
regulation of intracellular protein transportGO:0033157820.173
protein localization to organelleGO:00333651850.173
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.170
prostate gland epithelium morphogenesisGO:0060740310.170
labyrinthine layer morphogenesisGO:0060713210.170
regulation of fibronectin dependent thymocyte migrationGO:200041310.169
positive regulation of immunoglobulin productionGO:0002639280.168
t cell differentiation involved in immune responseGO:0002292300.168
positive regulation of atp biosynthetic processGO:200117120.167
cytokine biosynthetic processGO:0042089680.167
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.166
endocrine system developmentGO:0035270980.166
negative regulation of cellular amine metabolic processGO:003323910.165
response to interleukin 2GO:007066920.165
interleukin 2 biosynthetic processGO:0042094150.165
branching morphogenesis of an epithelial tubeGO:00487541590.164
negative regulation of wnt signaling pathwayGO:0030178730.164
activation of cysteine type endopeptidase activityGO:0097202270.163
regulation of interleukin 2 productionGO:0032663280.163
negative regulation of cellular protein metabolic processGO:00322692470.163
regulation of acute inflammatory responseGO:0002673270.163
carbohydrate metabolic processGO:00059752300.162
cation transportGO:00068123990.162
positive regulation of hydrolase activityGO:00513451480.162
positive regulation of alkaline phosphatase activityGO:001069430.161
regulation of response to woundingGO:19030341890.161
Zebrafish
response to inactivityGO:001485440.161
blood vessel morphogenesisGO:00485142850.160
nitric oxide mediated signal transductionGO:000726340.160
regulation of membrane protein ectodomain proteolysisGO:005104330.160
positive regulation of transferase activityGO:00513471670.159
mitotic cell cycleGO:00002781950.158
immune response activating signal transductionGO:00027571160.158
hormone mediated signaling pathwayGO:0009755230.158
endochondral bone morphogenesisGO:0060350500.157
retina development in camera type eyeGO:00600411190.157
regulation of membrane potentialGO:00423911920.156
somatic cell dna recombinationGO:0016444510.156
Mouse
striated muscle tissue developmentGO:00147062930.155
regulation of protein maturationGO:1903317960.155
lipid localizationGO:00108761260.155
inflammatory response to antigenic stimulusGO:0002437300.155
liver developmentGO:0001889660.154
regulation of peptide transportGO:0090087910.154
prevention of polyspermyGO:006046840.154
cellular response to insulin stimulusGO:0032869780.154
interferon gamma mediated signaling pathwayGO:006033350.154
positive regulation of epithelial cell proliferationGO:0050679680.153
cell substrate adhesionGO:00315891300.153
negative regulation of intracellular protein transportGO:0090317270.152
reactive nitrogen species metabolic processGO:200105700.152
regulation of eosinophil migrationGO:200041620.152
maintenance of locationGO:0051235890.151
negative regulation of neuron differentiationGO:00456651010.150
defense response to gram negative bacteriumGO:0050829280.147
interleukin 2 mediated signaling pathwayGO:003811020.147
nuclear divisionGO:00002801580.147
astrocyte differentiationGO:0048708430.146
positive regulation of cd4 positive alpha beta t cell differentiationGO:0043372140.146
regulation of cell substrate adhesionGO:0010810730.146
positive regulation of smad protein import into nucleusGO:006039120.145
positive regulation of mast cell differentiationGO:006037610.145
cellular response to molecule of bacterial originGO:0071219830.144
regulation of epithelial cell proliferationGO:00506781410.144
regulation of thymocyte apoptotic processGO:0070243140.143
epithelial tube morphogenesisGO:00605623030.143
negative regulation of nik nf kappab signalingGO:190122320.142
regulation of actin filament based processGO:0032970990.142

Il6st disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inflammatory bowel diseaseDOID:005058900.343
disease of anatomical entityDOID:700.343
gastrointestinal system diseaseDOID:7700.343
intestinal diseaseDOID:529500.343
disease of metabolismDOID:001466700.216
acquired metabolic diseaseDOID:006015800.216
musculoskeletal system diseaseDOID:1700.188
connective tissue diseaseDOID:6500.188